Patents
US 8632983 B2: Biomarkers for pancreatic cancer and diagnostic methods
- Granted
- 2014-01-21
- Filed
- 2010-11-22 application 12951718
- Type
- Utility · 10 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Methods and related kits for differentiating pancreatic cancer from a benign pancreatic disease. The method includes assaying a patient biological sample for a total level of CA 19-9 antigen and for a glycan level in specific mucin(s), and comparing the total level of CA 19-9 antigen and the glycan level in the specific mucin(s) to statistically validated thresholds, wherein a different level of total CA 19-9 antigen in the patient biological sample as compared to a statistically validated threshold and a different level of glycan level in the specific mucin(s) as compared to statistically validated thresholds indicate pancreatic cancer in the patient rather than a benign pancreatic disease.
Source: PVGPATDIS, file of 2026-04-10 (ipg140121.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| VAN ANDEL RESEARCH INSTITUTE 19 patents | US company or organization | Grand Rapids, MI | VAN ANDEL RESEARCH INSTITUTE Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
| University of Pittsburgh—Of the Commonwealth System of Higher Education 1,390 patents | US company or organization | Pittsburgh, PA | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Brian B. Haab | Jenison, MI | 3 | PVGPATDIS, file of 2026-04-10 | |
| Tingting Yue | Cary, NC | 1 | PVGPATDIS, file of 2026-04-10 | |
| Randall E. Brand | Dorpsstraat, PA | 5 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N33/5308 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2012-08-20 | Government interest Confirmatory license | VAN ANDEL RESEARCH INSTITUTE signed 2012-08-03 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT BETHESDA, MD | 28812/615 | ECORSEXC, file of 2026-09-25 |
| 2011-06-29 | Assignment Assignment of assignor's interest | BRAND, RANDALL E. signed 2011-03-28 | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION PITTSBURGH, PA | 26522/704 | ECORSEXC, file of 2026-09-25 |
| 2011-06-29 | Assignment Assignment of assignor's interest | YUE, TINGTING signed 2011-06-17 | VAN ANDEL RESEARCH INSTITUTE GRAND RAPIDS, MI | 26522/621 | ECORSEXC, file of 2026-09-25 |
| 2011-06-29 | Assignment Assignment of assignor's interest | HAAB, BRIAN B. signed 2011-02-11 | VAN ANDEL RESEARCH INSTITUTE GRAND RAPIDS, MI | 26522/417 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.