Patents
US 8563513 B2: Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
- Granted
- 2013-10-22
- Filed
- 2010-03-26 application 13260699
- Type
- Utility · 31 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Provided herein are Parathyroid hormone (PTH) peptides and parathyroid hormone-related protein (PTHrP) peptides (e.g., PTH analogs, PTHrP analogs), and related variants, chemical derivatives, fusion polypeptides, multimeric polypeptides, and peptidomimetics, peptoids, the like. Also provided are their use in methods for activating the PTH receptor in a cell (e.g., an osteoblast), methods of treating a subject with bone loss (e.g., by administration of a PTH peptide or PTHrP peptide (e.g., a PTH analog or PTHrP analog)), methods of ameliorating a symptom associated with osteoporosis in a subject, methods of retarding the progression of osteoporosis in a subject, and methods of regenerating bone in a subject.
Source: PVGPATDIS, file of 2026-04-10 (ipg131022.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| VAN ANDEL RESEARCH INSTITUTE 19 patents | US company or organization | Grand Rapids, MI | VAN ANDEL RESEARCH INSTITUTE Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
| The General Hospital Corporation 1,995 patents | US company or organization | Boston, MA | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Huaqiang Eric Xu | Grand Rapids, MI | 11 | PVGPATDIS, file of 2026-04-10 | |
| Augen A. Pioszak | Edmond, OK | 4 | PVGPATDIS, file of 2026-04-10 | |
| Thomas J. Gardella | Needham, MA | 12 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07K | Peptides | C07K14/635 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P19/10 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K38/00 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2023-02-18 | Government interest Confirmatory license | MASSACHUSETTS GENERAL HOSPITAL signed 2023-02-16 | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR BETHESDA, MD | 62737/822 | ECORSEXC, file of 2026-09-25 |
| 2013-06-06 | Government interest Confirmatory license | THE GENERAL HOSPITAL CORPORATION signed 2013-06-03 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT BETHESDA, MD | 30572/327 | ECORSEXC, file of 2026-09-25 |
| 2011-11-02 | Assignment Assignment of assignor's interest | PIOSZAK, AUGEN A. signed 2010-08-20 XU, HUAQIANG ERIC signed 2010-08-30 | VAN ANDEL RESEARCH INSTITUTE GRAND RAPIDS, MI | 27160/614 | ECORSEXC, file of 2026-09-25 |
| 2011-11-02 | Assignment Assignment of assignor's interest | GARDELLA, THOMAS J. signed 2010-05-18 | THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL BOSTON, MA | 27160/592 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.