Patents
US 12723075 B2: Humanized antibodies directed against KCNK9
- Granted
- 2026-09-01
- Filed
- 2021-06-03 application 17928996
- Type
- Utility · 17 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Provided herein are humanized monoclonal antibodies that bind to potassium two pore domain channel subfamily K member 9 (KCNK9). The humanized monoclonal antibodies comprise (a) a heavy chain variable region comprising an amino acid sequence of SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, or SEQ ID NO: 13; and (b) a light chain variable region comprising an amino acid sequence of SEQ ID NO: 14, SEQ ID NO: 15, or SEQ ID NO: 16. Methods of using the antibodies to inhibit the growth of KCNK9-expressing cells also are provided.
Source: PTBLXML, file of 2026-09-01 (ipgb20260901.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| THE JOHNS HOPKINS UNIVERSITY 2,182 patents | US company or organization | Baltimore, MD | Johns Hopkins University College or university FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PTBLXML, file of 2026-09-01 |
| UNIVERSITY OF MARYLAND, BALTIMORE 656 patents | US company or organization | Baltimore, MD | University of Maryland, Baltimore College or university EXACT high confidence: identical full name and state UNIVERSITY OF MARYLAND, BALTIMORE Federal lobbying client EXACT high confidence: identical full name and state | PTBLXML, file of 2026-09-01 |
| THE KENNEDY KRIEGER INSTITUTE, INC. 20 patents | US company or organization | Baltimore, MD | KENNEDY KRIEGER INSTITUTE, INC. State business registration EXACT high confidence: identical full name and state KENNEDY KRIEGER INSTITUTE INC Nonprofit EXACT high confidence: identical full name and state KENNEDY KRIEGER INSTITUTE Federal lobbying client FUZZY medium confidence: same name (legal endings aside) and state | PTBLXML, file of 2026-09-01 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| John J. Laterra | Baltimore, MD | PTBLXML, file of 2026-09-01 | ||
| Amy M. Fulton | Baltimore, MD | PTBLXML, file of 2026-09-01 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07K | Peptides | C07K16/28 | PTBLXML, file of 2026-09-01 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PTBLXML, file of 2026-09-01 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K2039/505 | PTBLXML, file of 2026-09-01 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.