Patents
US 12674206 B2: Systems and methods for treating patients having a genetic predisposition to develop prostate cancer
- Granted
- 2026-07-07
- Filed
- 2020-06-16 application 16902552
- Type
- Utility · 22 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Systems and methods for mitigating prostate cancer development are provided. Peripheral blood cells may be evaluated for the presence or quantity of gamma-H2AX foci, and/or for gene alterations encoding a protein with impaired or lack of function, for example, because the encoded protein is truncated, and correlating with prostate cancer development. Such nucleic acids may encode proteins from or peripheral to the DNA damage repair pathway and/or androgen receptor signaling pathway, or that are otherwise correlated with prostate cancer development. Such genes include one or more of AKR1C1, PALB2, APTX, BLM, BRCA1, CTBP1, DDB2, FANCA, FANCL, MBD5, MSH3, NEIL3, RAD51D, RAD54L2, SP1, TP53BP1, UBE2D3, UBE2V2, NRIP1, EFCAB6, CRISP3, PAPSS2, ATP6V0A2, ALG13, MGAT2, B3GAT3, DOLK, FLT3, ASXL1, KDR, or NOTCH2.
Source: PTBLXML, file of 2026-07-07 (ipgb20260707.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| INSTITUTE FOR CANCER RESEARCH 70 patents | US company or organization | Philadelphia, PA | INSTITUTE FOR CANCER RESEARCH Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-07-07 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Sanjeevani Arora | Philadelphia, PA | 3 | PTBLXML, file of 2026-07-07 | |
| Greg Enders | Philadelphia, PA | PTBLXML, file of 2026-07-07 | ||
| Erica Golemis | Philadelphia, PA | PTBLXML, file of 2026-07-07 | ||
| Emmanuelle Nicolas | Philadelphia, PA | 2 | PTBLXML, file of 2026-07-07 | |
| Ilya Serebriiskii | Philadelphia, PA | 6 | PTBLXML, file of 2026-07-07 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12Q | Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processes | C12Q1/6886 | PTBLXML, file of 2026-07-07 |
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N33/57555 | PTBLXML, file of 2026-07-07 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.