Patents
US 12637502 B2: Netrin G1 polypeptides
- Granted
- 2026-05-26
- Filed
- 2020-04-24 application 17604891
- Type
- Utility · 6 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present disclosure provides polypeptides of netrin G1 (NetG1) and its cell surface receptor netrin G1 ligand (NGL1), and antibodies thereto, and methods of making such antibodies. The disclosure also provides uses of these NetG1 and NGL1 polypeptides, and antibodies thereto, in methods of treating cancers and diseases, including chronic fibrosis, inflammation, and inflammation-related diseases.
Source: PTBLXML, file of 2026-05-26 (ipgb20260526.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| INSTITUTE FOR CANCER RESEARCH 70 patents | US company or organization | Philadelphia, PA | INSTITUTE FOR CANCER RESEARCH Nonprofit EXACT high confidence: identical full name and state | PTBLXML, file of 2026-05-26 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Edna Cukierman | Philadelphia, PA | 2 | PTBLXML, file of 2026-05-26 | |
| Ralph Francescone | Philadelphia, PA | 2 | PTBLXML, file of 2026-05-26 | |
| Debora Vendramini-Costa | Philadelphia, PA | PTBLXML, file of 2026-05-26 | ||
| Kristopher Raghavan | Philadelphia, PA | 2 | PTBLXML, file of 2026-05-26 | |
| Janusz Franco-Barraza | Philadelphia, PA | 2 | PTBLXML, file of 2026-05-26 | |
| Roland Dunbrack | Philadelphia, PA | 5 | PTBLXML, file of 2026-05-26 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C07K | Peptides | C07K14/71 | PTBLXML, file of 2026-05-26 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/00 | PTBLXML, file of 2026-05-26 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-03-04 | Assignment Assignment of assignor's interest | CUKIERMAN, EDNA signed 2022-02-23 FRANCESCONE, RALPH signed 2022-02-21 VENDRAMINI-COSTA, DEBORA signed 2022-02-22 RAGHAVAN, KRISTOPHER signed 2022-03-02 FRANCO-BARRAZA, JANUSZ signed 2022-02-23 DUNBRACK, ROLAND signed 2022-02-22 | INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER PHILADELPHIA, PA | 59173/972 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.