Patents
US 12622975 B2: Peptide-conjugated prodrugs
- Granted
- 2026-05-12
- Filed
- 2020-09-18 application 17761496
- Type
- Utility · 14 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present disclosure relates to a conjugated prodrug comprising a peptide conjugated to an antibiotic molecules via a cleavable linker and pharmaceutical compositions thereof. Also disclosed are methods of enhancing the intracellular concentration of an antibiotic agent in a bacterium and methods of treating a patient for a bacterial infection.
Source: PTBLXML, file of 2026-05-12 (ipgb20260512.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| BRANDEIS UNIVERSITY 165 patents | US company or organization | Waltham, MA | Brandeis University College or university EXACT high confidence: identical full name and state BRANDEIS UNIVERSITY Federal lobbying client EXACT high confidence: identical full name and state BRANDEIS UNIVERSITY Nonprofit EXACT high confidence: identical full name and state BRANDEIS UNIVERSITY INC. State business registration FUZZY medium confidence: same name (legal endings aside) and state | PTBLXML, file of 2026-05-12 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Bing Xu | Newton, MA | 27 | PTBLXML, file of 2026-05-12 | |
| Jiaqing Wang | Waltham, MA | PTBLXML, file of 2026-05-12 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K47/64 | PTBLXML, file of 2026-05-12 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P31/04 | PTBLXML, file of 2026-05-12 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-12-09 | Assignment Assignment of assignor's interest | XU, BING signed 2022-07-14 WANG, JIAQING signed 2022-07-19 | BRANDEIS UNIVERSITY WALTHAM, MA | 62037/347 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.