Patents
US 12595490 B2: Non-HLA matched humanized NSG mouse model with patient-derived xenograft
- Granted
- 2026-04-07
- Filed
- 2022-01-06 application 17569788
- Type
- Utility · 4 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The invention described herein provides non-HLA matched humanized mouse model (e.g., NSG mouse model) with patient-derived xenograft (PDX), as well as methods of making and using the same.
Source: PTBLXML, file of 2026-04-07 (ipgb20260407.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The Jackson Laboratory 76 patents | US company or organization | Bar Harbor, ME | JACKSON LABORATORY Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PTBLXML, file of 2026-04-07 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| James Keck | Granite Bay, CA | 9 | PTBLXML, file of 2026-04-07 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/8509 | PTBLXML, file of 2026-04-07 |
| A01K | Animal husbandry; aviculture; apiculture; pisciculture; fishing; rearing or breeding animals, not otherwise provided for; new breeds of animals | A01K67/0271 | PTBLXML, file of 2026-04-07 |
| C07K | Peptides | C07K14/55 | PTBLXML, file of 2026-04-07 |
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N33/5088 | PTBLXML, file of 2026-04-07 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-10-07 | Assignment Assignment of assignor's interest | KECK, JAMES signed 2018-07-17 | THE JACKSON LABORATORY BAR HARBOR, ME | 61349/238 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.