Patents
US 12485174 B2: HDAC6-activated macrophages, compositions, and uses thereof
- Granted
- 2025-12-02
- Filed
- 2020-06-26 application 17623050
- Type
- Utility · 10 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present disclosure provides histone deacetylase 6 (HDAC6)-activated macrophages, compositions comprising HDAC6-activated macrophages, methods of making HDAC6-activated macrophages, and methods of treating diseases, e.g., cancer, by administering a therapeutically effective amount of HDAC6-activated macrophages.
Source: PVGPATDIS, file of 2026-04-10 (ipg251202.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION 31 patents | US company or organization | Washington, DC | PVGPATDIS, file of 2026-04-10 | |
| MEDSTAR HEALTH, INC. 21 patents | US company or organization | Columbia, MD | MEDSTAR HEALTH, INC. State business registration EXACT high confidence: identical full name and state MEDSTAR HEALTH, INC. Federal lobbying client EXACT high confidence: identical full name and state MEDSTAR HEALTH INC Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Alejandro V. Villagra | Falls Church, VA | 11 | PVGPATDIS, file of 2026-04-10 | |
| Nima Aghdam | Alexandria, VA | 1 | PVGPATDIS, file of 2026-04-10 | |
| Satish NOONEPALLE | Falls Church, VA | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61K | Preparations for medical, dental or toiletry purposes | A61K45/06 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P35/04 | PVGPATDIS, file of 2026-04-10 |
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N5/0645 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2026-06-01 | Correction Corrective assignment to correct the assignee name: medstar health, inc. previously recorded on reel 58487 frame 503. assignor(s) hereby confirms the assignment. | AGHDAM, NIMA signed 2020-07-08 | MEDSTAR HEALTH, INC. COLUMBIA, MD | 76200/17 | PASDL, file of 2026-10-07 |
| 2021-12-28 | Assignment Assignment of assignor's interest | AGHDAM, NIMA signed 2020-07-08 | MEDSTAR HEALTH COLUMBIA, MD | 58487/503 | ECORSEXC, file of 2026-09-25 |
| 2021-12-28 | Assignment Assignment of assignor's interest | NOONEPALLE, SATISH signed 2020-07-07 VILLAGRA, ALEJANDRO signed 2020-07-07 | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION WASHINGTON, DC | 58487/441 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.