Patents

US 12428638 B2: Three-component CRISPR/Cas complex system and uses thereof

Granted
2025-09-30
Filed
2022-07-28 application 17815621
Type
Utility · 20 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The invention described herein provides compositions and reagents for assembling a tripartite complex at a specific location of a target DNA. The invention also provides methods for using the complex to, for example, label a specific genomic locus, to regulate the expression of a target gene, or to create a gene regulatory network.

Source: PVGPATDIS, file of 2026-04-10 (ipg250930.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
The Jackson Laboratory 76 patentsUS company or organizationBar Harbor, MEJACKSON LABORATORY Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and statePVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Haoyi WangBeijing, CN3PVGPATDIS, file of 2026-04-10
Albert ChengBar Harbor, ME8PVGPATDIS, file of 2026-04-10
Nathaniel JilletteBar Harbor, ME3PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
C12NMicroorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture mediaC12N15/11PVGPATDIS, file of 2026-04-10
C07KPeptidesC07K2319/09PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2022-11-02Assignment
Assignment of assignor's interest
WANG, HAOYI signed 2018-02-08
CHENG, ALBERT signed 2018-03-20
JILLETTE, NATHANIEL signed 2018-03-20
THE JACKSON LABORATORY BAR HARBOR, ME61632/91ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.