Patents

US 12414979 B2: Compositions and methods for treating Sjogren's syndrome

Granted
2025-09-16
Filed
2021-11-03 application 17517886
Type
Utility · 10 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

The present invention provides compositions and methods for treating Sjogren's syndrome (SS), including primary or secondary SS, as well as methods for preventing clinical disease in patients at risk of developing clinical SS. In various embodiments, the invention relates to administering a regimen of larazotide (or derivative) and/or 4-APAA compounds or 5-ASA compounds (e.g., 5-ASA, 4-ASA, 4-Ac APAA, and 4-APAA) to a patient in need thereof.

Source: PVGPATDIS, file of 2026-04-10 (ipg250916.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
Interlude Biopharma Co. 2 patentsUS company or organizationMiami, FLPVGPATDIS, file of 2026-04-10
Oklahoma Medical Research Foundation 57 patentsUS company or organizationOklahoma City, OKOKLAHOMA MEDICAL RESEARCH FOUNDATION Nonprofit EXACT high confidence: identical full name and statePVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Jay P. MADANRaleigh, NC6PVGPATDIS, file of 2026-04-10
Kathy L. SivilsOklahoma City, OK1PVGPATDIS, file of 2026-04-10
Umesh DeshmukhOklahoma City, OK1PVGPATDIS, file of 2026-04-10
Balasingham RadhakrishnanRaleigh, NC3PVGPATDIS, file of 2026-04-10
Kendyle KennsengtenRaleigh, NC1PVGPATDIS, file of 2026-04-10
Harini BagavantOklahoma City, OK1PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
A61KPreparations for medical, dental or toiletry purposesA61K38/08PVGPATDIS, file of 2026-04-10
A61PSpecific therapeutic activity of chemical compounds or medicinal preparationsA61P1/02PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2024-05-21Name change
Change of name
EBRIS PHARMA CO. signed 2024-04-01INTERLUDE BIOPHARMA CO. MIAMI, FL67485/755ECORSEXC, file of 2026-09-25
2024-05-21Assignment
Assignment of assignor's interest
9 METERS BIOPHARMA, INC. signed 2024-01-08EBRIS PHARMA CO. MIAMI, FL67485/438ECORSEXC, file of 2026-09-25
2023-04-10Security interest Security interest
Intellectual property security agreement
9 METERS BIOPHARMA, INC. signed 2022-07-15
NAIA RARE DISEASES, LLC signed 2022-07-15
HIGH TRAIL SPECIAL SITUATIONS LLC HOBOKEN, NJ63281/653PASDL, file of 2026-10-15
2023-01-25Name change
Change of name
INNOVATE BIOPHARMACEUTICALS, INC. signed 2020-04-309 METERS BIOPHARMA, INC. RALEIGH, NC62493/13ECORSEXC, file of 2026-09-25
2023-01-25Assignment
Assignment of assignor's interest
MADAN, JAY P. signed 2020-04-13
RADHAKRISHNAN, BALASINGHAM signed 2020-04-13
WOODARD, KENDYLE signed 2020-04-13
BAGAVANT, HARINI signed 2020-04-20
DESHMUKH, UMESH signed 2020-04-20
SIVILS, KATHY L. signed 2020-04-20
INNOVATE BIOPHARMACEUTICALS, INC. RALEIGH, NC62480/265ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.