Patents
US 12409237 B1: Methods and models for assessing efficacy of immunotherapies
- Granted
- 2025-09-09
- Filed
- 2024-06-28 application 18758838
- Type
- Utility · 10 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A method of identifying anti-tumor activity of a test substance is provided along with a genetically-modified, immunodeficient mouse and methods of use, wherein the genetically-modified, immunodeficient mouse enables in vivo investigation of the interactions between the human immune system and human cancer.
Source: PVGPATDIS, file of 2026-04-10 (ipg250909.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The Jackson Laboratory 76 patents | US company or organization | Bar Harbor, ME | JACKSON LABORATORY Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PVGPATDIS, file of 2026-04-10 |
| University of Massachusetts 1,152 patents | US company or organization | Westborough, MA | UNIVERSITY OF MASSACHUSETTS Federal lobbying client EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Leonard D. Shultz | Bar Harbor, ME | 10 | PVGPATDIS, file of 2026-04-10 | |
| James Keck | Bar Harbor, ME | 9 | PVGPATDIS, file of 2026-04-10 | |
| Dale L. Greiner | Westborough, MA | 8 | PVGPATDIS, file of 2026-04-10 | |
| Michael A. Brehm | Westborough, MA | 7 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A01K | Animal husbandry; aviculture; apiculture; pisciculture; fishing; rearing or breeding animals, not otherwise provided for; new breeds of animals | A01K67/0278 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K49/0008 | PVGPATDIS, file of 2026-04-10 |
| C07K | Peptides | C07K14/53 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2024-10-18 | Correction Corrective assignment to correct the the name of the first name of the first inventor previously recorded at reel: 68772 frame: 983. assignor(s) hereby confirms the assignment. | KECK, JAMES G. signed 2021-08-02 SHULTZ, LEONARD D. signed 2021-08-02 | THE JACKSON LABORATORY BAR HARBOR, ME | 69208/353 | ECORSEXC, file of 2026-09-25 |
| 2024-10-02 | Assignment Assignment of assignor's interest | BREHM, MICHAEL A. signed 2021-08-02 GREINER, DALE L. signed 2021-08-02 | UNIVERSITY OF MASSACHUSETTS WESTBOROUGH, MA | 68773/68 | ECORSEXC, file of 2026-09-25 |
| 2024-10-02 | Assignment Assignment of assignor's interest | KECK, JAMES G. signed 2021-08-02 SHULTZ, LENNY D. signed 2021-08-02 | THE JACKSON LABORATORY BAR HARBOR, ME | 68772/963 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.