Patents
US 12146166 B2: Generation of induced pluripotent cells by CRISPR activation
- Granted
- 2024-11-19
- Filed
- 2018-12-27 application 16957086
- Type
- Utility · 13 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
The present Application is related to methods and compositions for reprogramming adult somatic cells into induced pluripotent stem cells by targeting and remodeling endogenous gene loci without relying on ectopic expression of transcription factors.
Source: PVGPATDIS, file of 2026-04-10 (ipg241119.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| The J. David Gladstone Institutes 72 patents | US company or organization | San Francisco, CA | J. DAVID GLADSTONE INSTITUTES State business registration FUZZY medium confidence: same name (legal endings aside) and state J DAVID GLADSTONE INSTITUTES Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Peng Liu | San Francisco, CA | 25 | PVGPATDIS, file of 2026-04-10 | |
| Sheng Ding | San Francisco, CA | 49 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N5/0696 | PVGPATDIS, file of 2026-04-10 |
| C07K | Peptides | C07K14/4702 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2022-03-15 | Assignment Assignment of assignor's interest | LIU, PENG signed 2019-08-09 DING, SHENG signed 2019-08-09 | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE SAN FRANCISCO, CA | 59267/421 | PASDL, file of 2026-10-15 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.