Patents
US 11732260 B2: Compounds and methods for the modulation of amyloid-β precursor protein
- Granted
- 2023-08-22
- Filed
- 2019-03-01 application 16977649
- Type
- Utility · 39 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Certain embodiments disclosed herein are directed to compounds and methods for modulating APP expression. In certain embodiments, modulating the splicing of amyloid precursor protein (APP) reduces amyloid β (Aβ) production.
Source: PVGPATDIS, file of 2026-04-10 (ipg230822.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Ionis Pharmaceuticals, Inc. 290 patents | US company or organization | Carlsbad, CA | IONIS PHARMACEUTICALS INC SEC filer EXACT medium confidence: identical full name, one of each nationally | PVGPATDIS, file of 2026-04-10 |
| Rosalind Franklin University of Medicine and Science 42 patents | US company or organization | North Chicago, IL | Rosalind Franklin University of Medicine and Science State business registration EXACT high confidence: identical full name and state Rosalind Franklin University of Medicine and Science College or university EXACT high confidence: identical full name and state ROSALIND FRANKLIN UNIVERSITY OF MEDICINE & SCIENCE Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Frank Rigo | Carlsbad, CA | 51 | PVGPATDIS, file of 2026-04-10 | |
| Michelle L. Hastings | North Chicago, IL | 13 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N15/113 | PVGPATDIS, file of 2026-04-10 |
| C07K | Peptides | C07K14/4711 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
No recorded assignments or security interests on file for this patent.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.