Patents

US 11618926 B2: Methods for diagnosing, prognosing, and treating colorectal cancer using biomarker expression

Granted
2023-04-04
Filed
2018-02-28 application 16489597
Type
Utility · 10 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Dysregulated expression of microRNAs (miRNAs) has emerged as a hallmark feature in human cancers. Aspects of the disclosure relate to methods for selecting optimal therapy for a patient from several alternative treatment options. A major clinical challenge in cancer treatment is to identify the subset of patients who will benefit from a therapeutic regimen, both in metastatic and adjuvant settings. The number of anti-cancer drugs and multi-drug combinations has increased substantially in the past decade, however, treatments continue to be applied empirically using a trial-and-error approach. Here methods and compositions are provided to determine the optimal treatment option for cancer patients.

Source: PVGPATDIS, file of 2026-04-10 (ipg230404_r1.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
BAYLOR RESEARCH INSTITUTE 79 patentsUS company or organizationDallas, TXBAYLOR RESEARCH INSTITUTE State business registration EXACT high confidence: identical full name and state
BAYLOR RESEARCH INSTITUTE Nonprofit EXACT high confidence: identical full name and state
PVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Ajay GoelDallas, TX11PVGPATDIS, file of 2026-04-10
Raju KandimallaDallas, TX1PVGPATDIS, file of 2026-04-10
Shusuke TodenDallas, TX1PVGPATDIS, file of 2026-04-10
Roshni RoyBaltimore, MD1PVGPATDIS, file of 2026-04-10
Tsuyoshi OzawaDallas, TX5PVGPATDIS, file of 2026-04-10
Takatoshi MatsuyamaDallas, TX1PVGPATDIS, file of 2026-04-10
Wenhao WengDallas, TX1PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
C12QMeasuring or testing processes involving enzymes, nucleic acids or microorganisms ; compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processesC12Q1/6886PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2019-08-28Assignment
Assignment of assignor's interest
GOEL, AJAY signed 2017-07-17
KANDIMALLA, RAJU signed 2017-07-20
ROY, ROSHNI signed 2017-07-20
TODEN, SHUSUKE signed 2017-07-20
OZAWA, TSUYOSHI signed 2017-07-21
MATSUYAMA, TAKATOSHI signed 2017-07-22
WENG, WENHAO signed 2017-07-25
BAYLOR RESEARCH INSTITUTE DALLAS, TX50203/31ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.