Patents
US 11559231 B2: System and method for determining a discrimination index for fear-potentiated startle
- Granted
- 2023-01-24
- Filed
- 2019-05-17 application 16414951
- Type
- Utility · 12 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
A method and system is provided for determining a discrimination index in a subject that may be suffering from or at risk for a stress-induced psychiatric disorder. The discrimination index may be equal to a ratio of a subject's cued fear response and non-cued fear response measured during a fear-potentiated startle (FPS) paradigm. Such a value may allow a physician or researcher to quantify how well a subject discriminates between signaled (cued) fear and un-signaled (non-cued) fear, which may be a biomarker for psychiatric disorders like post-traumatic stress disorder, panic disorder, phobias, and/or generalized anxiety disorder. The determined discrimination index may provide a standardized way of diagnosing and evaluating mental illnesses, more uniform treatment of patients, and/or more precise monitoring and evaluation of treatment efficacy.
Source: PVGPATDIS, file of 2026-04-10 (ipg230124_r1.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Rosalind Franklin University of Medicine and Science 42 patents | US company or organization | North Chicago, IL | Rosalind Franklin University of Medicine and Science State business registration EXACT high confidence: identical full name and state Rosalind Franklin University of Medicine and Science College or university EXACT high confidence: identical full name and state ROSALIND FRANKLIN UNIVERSITY OF MEDICINE & SCIENCE Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Joanna Dabrowska | North Chicago, IL | 1 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| A61B | Diagnosis; surgery; identification | A61B5/165 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K9/0043 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P25/22 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2023-08-10 | Government interest Confirmatory license | ROSALIND FRANKLIN UNIV OF MEDICINE & SCI signed 2021-02-01 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT BETHESDA, MD | 64548/910 | ECORSEXC, file of 2026-09-25 |
| 2019-05-17 | Assignment Assignment of assignor's interest | DABROWSKA, JOANNA signed 2019-05-16 | ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE NORTH CHICAGO, IL | 49208/633 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.