Patents

US 11155835 B2: Prokaryotic-eukaryotic hybrid viral vector for delivery of large cargos of genes and proteins into human cells

Granted
2021-10-26
Filed
2020-08-11 application 16990289
Type
Utility · 27 claims
Elsewhere
Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗

Abstract

Described is hybrid viral vector comprising: a first virus such as bacteriophage T4; one or more second virus such as adeno-associated virus (AAV) attached to the first virus through cross-bridges, such as avidin-biotin cross-bridges; one or more DNA molecules packaged in the first virus; one or more nucleic acid molecules packaged in the second virus; and one or more proteins displayed on the surface of the first virus. Also described are methods of making and using such a hybrid viral vector.

Source: PVGPATDIS, file of 2026-04-10 (ipg211026.xml).

Assignees

AssigneeTypePlaceAlso on furp.orgSource
The Catholic University of America 38 patentsUS company or organizationWashington, DCThe Catholic University of America College or university EXACT high confidence: identical full name and state
THE CATHOLIC UNIVERSITY OF AMERICA Federal lobbying client EXACT high confidence: identical full name and state
CATHOLIC UNIVERSITY OF AMERICA Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state
PVGPATDIS, file of 2026-04-10

Inventors

InventorPlacePatentsPerson pageSource
Venigalla B. RaoSilver Spring, MD22PVGPATDIS, file of 2026-04-10
Jingen ZHUWashington, DC4PVGPATDIS, file of 2026-04-10

CPC categories

SubclassCategoryFirst groupSource
C12NMicroorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture mediaC12N15/86PVGPATDIS, file of 2026-04-10

Cooperative Patent Classification, as currently assigned (one row per subclass).

Assignments and security interests

RecordedWhatFromToReel/frameSource
2020-09-11Assignment
Assignment of assignor's interest
RAO, VENIGALLA B. signed 2020-09-09
ZHU, JINGEN signed 2020-09-09
THE CATHOLIC UNIVERSITY OF AMERICA WASHINGTON, DC53742/106ECORSEXC, file of 2026-09-25

Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.

USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.