Patents
US 10927398 B2: Compositions for CYP450 phenotyping using saliva samples
- Granted
- 2021-02-23
- Filed
- 2016-11-30 application 15779788
- Type
- Utility · 18 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Disclosed are methods and compositions which may be used in human cytochrome P450 (CYP450) enzyme phenotyping. The methods and compositions typically utilize a mélange of substrates for different CYP450 enzymes which may be administered orally to a patient. Subsequently, the metabolites of the substrates may be detected in the patient's saliva as well as any non-metabolized substrates to calculate a metabolic ratio for any given CYP450 enzyme in order to generate a phenotypic CYP450 enzyme profile for the patient.
Source: PVGPATDIS, file of 2026-04-10 (ipg210223.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| Concordia University 17 patents | US company or organization | Mequon, WI | Concordia University-Wisconsin College or university FUZZY medium confidence: through the nonprofit with the college's EIN (same name (governing-board words and legal endings aside) and state) CONCORDIA UNIVERSITY INC Nonprofit FUZZY medium confidence: same name (governing-board words and legal endings aside) and state | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Joseph McGraw | Germantown, WI | 2 | PVGPATDIS, file of 2026-04-10 | |
| Armin Henry Gerhardt | Mettawa, IL | 6 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12Q | Measuring or testing processes involving enzymes, nucleic acids or microorganisms ; compositions or test papers therefor; processes of preparing such compositions; condition-responsive control in microbiological or enzymological processes | C12Q1/26 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K31/192 | PVGPATDIS, file of 2026-04-10 |
| G01N | Investigating or analysing materials by determining their chemical or physical properties | G01N33/743 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2025-04-04 | Assignment Assignment of assignor's interest | CONCORDIA UNIVERSITY, INC. signed 2025-03-25 | CU VENTURES, INC. MEQUON, WI | 70741/569 | ECORSEXC, file of 2026-09-25 |
| 2018-06-05 | Assignment Assignment of assignor's interest | GERHARDT, ARMIN signed 2016-11-30 MCGRAW, JOSEPH signed 2016-11-30 | CONCORDIA UNIVERSITY INC. MEQUON, WI | 45987/624 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.