Patents
US 10519213 B2: Fusion proteins of collagen-binding domain and parathyroid hormone
- Granted
- 2019-12-31
- Filed
- 2019-07-22 application 16517988
- Type
- Utility · 13 claims
- Elsewhere
- Google Patents ↗ · USPTO patent document ↗ · USPTO Patent Center record ↗
Abstract
Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.
Source: PVGPATDIS, file of 2026-04-10 (ipg191231.xml).
Assignees
| Assignee | Type | Place | Also on furp.org | Source |
|---|---|---|---|---|
| THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS 225 patents | US company or organization | Little Rock, AR | PVGPATDIS, file of 2026-04-10 | |
| OCHSNER CLINIC FOUNDATION 9 patents | US company or organization | New Orleans, LA | OCHSNER CLINIC FOUNDATION Nonprofit EXACT high confidence: identical full name and state | PVGPATDIS, file of 2026-04-10 |
| NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY 117 patents | Foreign company or organization | Samukawa, JP | PVGPATDIS, file of 2026-04-10 |
Inventors
| Inventor | Place | Patents | Person page | Source |
|---|---|---|---|---|
| Robert C. Gensure | Lexington, MA | 11 | PVGPATDIS, file of 2026-04-10 | |
| Joshua Sakon | Fayetteville, AR | 15 | PVGPATDIS, file of 2026-04-10 | |
| Osamu Matsushita | Okayama, JP | 14 | PVGPATDIS, file of 2026-04-10 | |
| Tulasi Ponnapakkam | Metairie, LA | 10 | PVGPATDIS, file of 2026-04-10 |
CPC categories
| Subclass | Category | First group | Source |
|---|---|---|---|
| C12N | Microorganisms or enzymes; compositions thereof; propagating, preserving, or maintaining microorganisms; mutation or genetic engineering; culture media | C12N9/64 | PVGPATDIS, file of 2026-04-10 |
| A61K | Preparations for medical, dental or toiletry purposes | A61K8/64 | PVGPATDIS, file of 2026-04-10 |
| A61P | Specific therapeutic activity of chemical compounds or medicinal preparations | A61P5/18 | PVGPATDIS, file of 2026-04-10 |
| A61Q | Specific use of cosmetics or similar toiletry preparations | A61Q7/00 | PVGPATDIS, file of 2026-04-10 |
| C07K | Peptides | C07K14/635 | PVGPATDIS, file of 2026-04-10 |
| C12Y | Enzymes | C12Y205/01018 | PVGPATDIS, file of 2026-04-10 |
Cooperative Patent Classification, as currently assigned (one row per subclass).
Assignments and security interests
| Recorded | What | From | To | Reel/frame | Source |
|---|---|---|---|---|---|
| 2019-09-10 | Assignment Assignment of assignor's interest | MATSUSHITA, OSAMU signed 2009-09-30 | NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY KAGAWA | 50329/254 | ECORSEXC, file of 2026-09-25 |
| 2019-09-10 | Assignment Assignment of assignor's interest | GENSURE, ROBERT C. signed 2013-03-15 PONNAPAKKAM, TULASI signed 2013-03-15 | OCHSNER CLINIC FOUNDATION NEW ORLEANS, LA | 50329/148 | ECORSEXC, file of 2026-09-25 |
| 2019-09-10 | Assignment Assignment of assignor's interest | SAKON, JOSHUA signed 2009-09-30 | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS LITTLE ROCK, AR | 50329/1 | ECORSEXC, file of 2026-09-25 |
Documents recorded with the USPTO Assignment Recordation Branch that list this patent. A security interest is a lender’s claim on the patent as collateral; a release ends it.
USPTO bulk data: PatentsView granted patents, disambiguated (PVGPATDIS) for patents, assignees, inventors, places and CPC categories; the USPTO Patent Assignment Dataset (ECORSEXC) for assignments and security interests. Patents filed in the last 20 years. No claims or full text. Links to other records are by name (and state): EXACT means the identical full name and state; FUZZY means a looser name match, with the confidence shown.