TRANSLATIONAL GENOMICS RESEARCH INSTITUTE FOUNDATION: Form 990, tax year 2009
View the entire original 990 at ProPublica ↗
- Organization
- TRANSLATIONAL GENOMICS RESEARCH INSTITUTE FOUNDATION (EIN 33-1092191)
- Tax period
- 2009-07-01 to 2010-06-30
- Filed
- 2011-05-25
- IRS object ID
- 201111459349300116
- Schema version
- 2009v1.7
- Source
- Download XML · Original 990 at ProPublica
Every field in the e-filed return. Faint text is the IRS element name, for citing.
Return header ReturnHeader
| Field | Value | IRS element (for citing) |
|---|---|---|
| Timestamp | 2011-05-25T16:26:35-05:00 | Timestamp |
| Tax Period End Date | 2010-06-30 | TaxPeriodEndDate |
Preparer Firm PreparerFirm
Preparer Firm Business Name PreparerFirmBusinessName
| Field | Value | IRS element (for citing) |
|---|---|---|
| Business Name Line1 | ERNST & YOUNG US LLP | BusinessNameLine1 |
Preparer Firm US Address PreparerFirmUSAddress
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | TWO NORTH CENTRAL AVENUE STE 2300 | AddressLine1 |
| City | PHOENIX | City |
| State | AZ | State |
| ZIP Code | 85004 | ZIPCode |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Return Type | 990 | ReturnType |
| Tax Period Begin Date | 2009-07-01 | TaxPeriodBeginDate |
Filer Filer
| Field | Value | IRS element (for citing) |
|---|---|---|
| EIN | 331092191 | EIN |
Name Name
| Field | Value | IRS element (for citing) |
|---|---|---|
| Business Name Line1 | THE TRANSLATIONAL GENOMICS RESEARCH INST FDN | BusinessNameLine1 |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Name Control | TRAN | NameControl |
| Phone | 6023438423 | Phone |
US Address USAddress
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | 400 E VAN BUREN SUITE 850 | AddressLine1 |
| City | PHOENIX | City |
| State | AZ | State |
| ZIP Code | 85004 | ZIPCode |
Officer Officer
| Field | Value | IRS element (for citing) |
|---|---|---|
| Name | MICHAEL BASSOFF | Name |
| Title | PRESIDENT | Title |
| Date Signed | 2011-05-16 | DateSigned |
Preparer Preparer
| Field | Value | IRS element (for citing) |
|---|---|---|
| Phone | 6023223000 | Phone |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Tax Year | 2009 | TaxYear |
| Build TS | 2016-02-24 21:20:13Z | BuildTS |
Form 990 IRS990
| Field | Value | IRS element (for citing) |
|---|---|---|
| Name Of Principal Officer Person | MICHAEL BASSOFF | NameOfPrincipalOfficerPerson |
Address Principal Officer US AddressPrincipalOfficerUS
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | 400 E VAN BUREN SUITE 850 | AddressLine1 |
| City | PHOENIX | City |
| State | AZ | State |
| ZIP Code | 85004 | ZIPCode |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Gross Receipts | 8955393 | GrossReceipts |
| Group Return For Affiliates | false | GroupReturnForAffiliates |
| Organization501c | X | Organization501c |
| Web Site | WWW.HELPTGEN.ORG | WebSite |
| Type Of Organization Corporation | X | TypeOfOrganizationCorporation |
| Year Formation | 2004 | YearFormation |
| State Legal Domicile | AZ | StateLegalDomicile |
| Activity Or Mission Description | BIOGENOMIC MEDICAL RESEARCH FUNDRAISING FOR THE TRANSLATIONAL GENOMICS RESEARCH INSITUTE (TGEN) | ActivityOrMissionDescription |
| Nbr Voting Members Governing Body | 19 | NbrVotingMembersGoverningBody |
| Nbr Independent Voting Members | 16 | NbrIndependentVotingMembers |
| Total Nbr Employees | 0 | TotalNbrEmployees |
| Total Nbr Volunteers | 63 | TotalNbrVolunteers |
| Total Gross UBI | 0 | TotalGrossUBI |
| Net Unrelated Business Txbl Income | 0 | NetUnrelatedBusinessTxblIncome |
| Contributions Grants Prior Year | 4359865 | ContributionsGrantsPriorYear |
| Contributions Grants Current Year | 8918909 | ContributionsGrantsCurrentYear |
| Program Service Revenue Prior Year | 0 | ProgramServiceRevenuePriorYear |
| Program Service Revenue CY | 0 | ProgramServiceRevenueCY |
| Investment Income Prior Year | 49477 | InvestmentIncomePriorYear |
| Investment Income Current Year | 36484 | InvestmentIncomeCurrentYear |
| Other Revenue Prior Year | 0 | OtherRevenuePriorYear |
| Other Revenue Current Year | 0 | OtherRevenueCurrentYear |
| Total Revenue Prior Year | 4409342 | TotalRevenuePriorYear |
| Total Revenue Current Year | 8955393 | TotalRevenueCurrentYear |
| Grants And Similar Amnts Prior Year | 4545907 | GrantsAndSimilarAmntsPriorYear |
| Grants And Similar Amnts CY | 4259390 | GrantsAndSimilarAmntsCY |
| Benefits Paid To Members Prior Year | 0 | BenefitsPaidToMembersPriorYear |
| Benefits Paid To Members CY | 0 | BenefitsPaidToMembersCY |
| Salaries Etc Prior Year | 1077559 | SalariesEtcPriorYear |
| Salaries Etc Current Year | 1094471 | SalariesEtcCurrentYear |
| Total Prof Fundrsng Exp Prior Year | 0 | TotalProfFundrsngExpPriorYear |
| Total Prof Fundrsng Exp CY | 0 | TotalProfFundrsngExpCY |
| Total Fundrsng Exp Current Year | 1298565 | TotalFundrsngExpCurrentYear |
| Other Expense Prior Year | 369195 | OtherExpensePriorYear |
| Other Expenses Current Year | 534251 | OtherExpensesCurrentYear |
| Total Expenses Prior Year | 5992661 | TotalExpensesPriorYear |
| Total Expenses Current Year | 5888112 | TotalExpensesCurrentYear |
| Revenues Less Expenses Prior Year | -1583319 | RevenuesLessExpensesPriorYear |
| Revenues Less Expenses CY | 3067281 | RevenuesLessExpensesCY |
| Total Assets BOY | 7543043 | TotalAssetsBOY |
| Total Assets EOY | 10267142 | TotalAssetsEOY |
| Total Liabilities BOY | 369491 | TotalLiabilitiesBOY |
| Total Liabilities EOY | 785648 | TotalLiabilitiesEOY |
| Net Assets Or Fund Balances BOY | 7173552 | NetAssetsOrFundBalancesBOY |
| Net Assets Or Fund Balances EOY | 9481494 | NetAssetsOrFundBalancesEOY |
| Mission Description | BIOGENOMIC MEDICAL RESEARCH FUNDRAISING FOR THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN). | MissionDescription |
| Significant New Program Services | false | SignificantNewProgramServices |
| Significant Change | false | SignificantChange |
| Expense | 4259390 | Expense |
| Grants | 4259390 | Grants |
| Description | SEE SCHEDULE O | Description |
| Total Program Service Expense | 4259390 | TotalProgramServiceExpense |
| Described In501 C3 | true | DescribedIn501C3 |
| Schedule B Required | true | ScheduleBRequired |
| Political Activities | false | PoliticalActivities |
| Lobbying Activities | false | LobbyingActivities |
| Donor Advised Funds | false | DonorAdvisedFunds |
| Conservation Easements | false | ConservationEasements |
| Collections Of Art | false | CollectionsOfArt |
| Credit Counseling | false | CreditCounseling |
| Term Or Permanent Endowments | true | TermOrPermanentEndowments |
| Balance Sheet Amounts Reported | true | BalanceSheetAmountsReported |
| Independent Audit Financial Stmt | false | IndependentAuditFinancialStmt |
| Consolidated Audit Financial Stmt | true | ConsolidatedAuditFinancialStmt |
| School | false | School |
| Foreign Office | false | ForeignOffice |
| Foreign Activities | false | ForeignActivities |
| More Than5000 K To Organizations | false | MoreThan5000KToOrganizations |
| More Than5000 K To Individuals | false | MoreThan5000KToIndividuals |
| Professional Fundraising | false | ProfessionalFundraising |
| Fundraising Activities | false | FundraisingActivities |
| Gaming | false | Gaming |
| Hospital | false | Hospital |
| Grants To Organizations | true | GrantsToOrganizations |
| Grants To Individuals | false | GrantsToIndividuals |
| Schedule J Required | true | ScheduleJRequired |
| Tax Exempt Bonds | false | TaxExemptBonds |
| Excess Benefit Transaction | false | ExcessBenefitTransaction |
| Prior Excess Benefit Transaction | false | PriorExcessBenefitTransaction |
| Loan To Officer Or DQP | false | LoanToOfficerOrDQP |
| Grant To Related Person | false | GrantToRelatedPerson |
| Bsnss Rltnshp With Organization | false | BsnssRltnshpWithOrganization |
| Bsnss Rltnshp Thru Family Member | false | BsnssRltnshpThruFamilyMember |
| Officer Entity With Bsnss Rltnshp | false | OfficerEntityWithBsnssRltnshp |
| Deductible Non Cash Contributions | false | DeductibleNonCashContributions |
| Deductible Contributions Of Art | false | DeductibleContributionsOfArt |
| Terminated | false | Terminated |
| Partial Liquidation | false | PartialLiquidation |
| Disregarded Entity | false | DisregardedEntity |
| Related Entity | true | RelatedEntity |
| Related Org Controlled Entity | true | RelatedOrgControlledEntity |
| Transfers To Exempt Non Chrtbl Org | false | TransfersToExemptNonChrtblOrg |
| Activities Conducted Partnership | false | ActivitiesConductedPartnership |
| Schedule O Required | true | ScheduleORequired |
| Number Forms Transmitted With1096 | 2 | NumberFormsTransmittedWith1096 |
| Number W2 G Included | 0 | NumberW2GIncluded |
| Compliance With Backup Witholding | true | ComplianceWithBackupWitholding |
| Number Of Employees | 0 | NumberOfEmployees |
| Unrelated Business Income | false | UnrelatedBusinessIncome |
| Foreign Financial Account | false | ForeignFinancialAccount |
| Prohibited Tax Shelter Trans | false | ProhibitedTaxShelterTrans |
| Taxable Party Notification | false | TaxablePartyNotification |
| Non Deductible Contributions | false | NonDeductibleContributions |
| Quid Pro Quo Contributions | false | QuidProQuoContributions |
| Form8282 Property Disposed Of | false | Form8282PropertyDisposedOf |
| Funds To Pay Premiums | false | FundsToPayPremiums |
| Premiums Paid | false | PremiumsPaid |
| Nbr Voting Governing Body Members | 19 | NbrVotingGoverningBodyMembers |
| Number Independent Voting Members | 16 | NumberIndependentVotingMembers |
| Family Or Business Relationship | false | FamilyOrBusinessRelationship |
| Delegation Of Management Duties | false | DelegationOfManagementDuties |
| Changes To Organizing Docs | false | ChangesToOrganizingDocs |
| Material Diversion Or Misuse | false | MaterialDiversionOrMisuse |
| Members Or Stockholders | true | MembersOrStockholders |
| Election Of Board Members | true | ElectionOfBoardMembers |
| Decisions Subject To Approval | true | DecisionsSubjectToApproval |
| Minutes Of Governing Body | true | MinutesOfGoverningBody |
| Minutes Of Committees | true | MinutesOfCommittees |
| Officer Mailing Address | false | OfficerMailingAddress |
| Local Chapters | false | LocalChapters |
| Form990 Provided To Governing Body | true | Form990ProvidedToGoverningBody |
| Conflict Of Interest Policy | true | ConflictOfInterestPolicy |
| Annual Disclosure Covered Persons | true | AnnualDisclosureCoveredPersons |
| Regular Monitoring Enforcement | true | RegularMonitoringEnforcement |
| Whistleblower Policy | true | WhistleblowerPolicy |
| Document Retention Policy | true | DocumentRetentionPolicy |
| Compensation Process CEO | true | CompensationProcessCEO |
| Compensation Process Other | true | CompensationProcessOther |
| Investment In Joint Venture | false | InvestmentInJointVenture |
| States Where Copy Of Return Is Filed | AZ | StatesWhereCopyOfReturnIsFiled |
| Upon Request | X | UponRequest |
The Books Are In Care Of TheBooksAreInCareOf
| Field | Value | IRS element (for citing) |
|---|---|---|
| Name Person | ELIZABETH MONTEMAYOR | NamePerson |
| Telephone Number | 6023438508 | TelephoneNumber |
Address US AddressUS
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | 400 E VAN BUREN SUITE 850 | AddressLine1 |
| City | PHOENIX | City |
| State | AZ | State |
| ZIP Code | 85004 | ZIPCode |
Form990 Part VII Section A Form990PartVIISectionA (20 entries)
| TitleTitle | Average Hours Per WeekAverageHoursPerWeek | Individual Trustee Or DirectorIndividualTrusteeOrDirector | OfficerOfficer | Reportable Comp From OrganizationReportableCompFromOrganization | Reportable Comp From Related OrgsReportableCompFromRelatedOrgs | Other CompensationOtherCompensation | Highest Compensated EmployeeHighestCompensatedEmployee |
|---|---|---|---|---|---|---|---|
| MICHAEL BASSOFF | |||||||
| DIRECTOR/PRESIDENT | 40.0 | X | X | 0 | 437239 | 15791 | |
| JOSE CARDENAS | |||||||
| DESIGNATED DIRECTOR/TGEN CHAIR | 1.0 | X | 0 | 0 | 0 | ||
| BENNETT DORRANCE | |||||||
| CHAIRMAN/DESIGNATED DIRECTOR | 1.0 | X | X | 0 | 0 | 0 | |
| JERRY BISGROVE | |||||||
| DIRECTOR | 1.0 | X | 0 | 0 | 0 | ||
| KARL ELLER | |||||||
| DIRECTOR | 1.0 | X | 0 | 0 | 0 | ||
| DIANE HALLE | |||||||
| DIRECTOR | 1.0 | X | 0 | 0 | 0 | ||
| LEE HANLEY | |||||||
| DIRECTOR | 1.0 | X | 0 | 0 | 0 | ||
| MIKE INGRAM | |||||||
| DIRECTOR | 1.0 | X | 0 | 0 | 0 | ||
| CATHERINE IVY | |||||||
| DIRECTOR | 1.0 | X | 0 | 0 | 0 | ||
| KEN KENDRICK | |||||||
| SECRETARY/DIRECTOR | 1.0 | X | X | 0 | 0 | 0 | |
| RICHARD LEHMANN | |||||||
| TREASURER/DIRECTOR | 1.0 | X | X | 0 | 0 | 0 | |
| F FRANCIS NAJAFI | |||||||
| DIRECTOR | 1.0 | X | 0 | 0 | 0 | ||
| THE HONORABLE SKIP RIMSZA | |||||||
| DIRECTOR | 1.0 | X | 0 | 0 | 0 | ||
| RAY THURSTON | |||||||
| DIRECTOR | 1.0 | X | 0 | 0 | 0 | ||
| PHIL FRANCIS | |||||||
| DIRECTOR | 1.0 | X | 0 | 0 | 0 | ||
| JEFFREY M TRENT PHD | |||||||
| DESIGNATED DIRECTOR/TGEN PRES | 1.0 | X | 0 | 1046046 | 17553 | ||
| TERESA BURLESON | |||||||
| DESIGNATED DIRECTOR/TGEN COO | 1.0 | X | 0 | 375130 | 17553 | ||
| TROY RICHARDS | |||||||
| DIRECTOR | 1.0 | X | 0 | 0 | 0 | ||
| HOWARD YOUNG | |||||||
| DIRECTOR | 1.0 | X | 0 | 0 | 0 | ||
| DENISE MCCLINTIC | |||||||
| ASSOCIATE VP MAJOR GIFTS | 40.0 | 0 | 166962 | 10071 | X | ||
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Reportable Comp From Org | 0 | TotalReportableCompFromOrg |
| Total Reportable Comp Frm Rltd Orgs | 2025377 | TotalReportableCompFrmRltdOrgs |
| Total Other Compensation | 60968 | TotalOtherCompensation |
| Number Individuals GT100 K | 0 | NumberIndividualsGT100K |
| Formers Listed | false | FormersListed |
| Total Comp GT150 K | true | TotalCompGT150K |
| Compensation From Other Sources | false | CompensationFromOtherSources |
Contractor Compensation ContractorCompensation
Name Of Contractor NameOfContractor
| Field | Value | IRS element (for citing) |
|---|---|---|
| Name Person | TRANSLATIONAL GENOMICS RESEARCH INS | NamePerson |
Address Of Contractor AddressOfContractor
Address US AddressUS
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | 445 NORTH 5TH STREET STE 600 | AddressLine1 |
| City | PHOENIX | City |
| State | AZ | State |
| ZIP Code | 85004 | ZIPCode |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Description Of Services | MANAGEMENT | DescriptionOfServices |
| Compensation | 108000 | Compensation |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Number Of Contractors GT100 K | 2 | NumberOfContractorsGT100K |
| All Other Contributions | 8918909 | AllOtherContributions |
| Noncash Contributions | 12595 | NoncashContributions |
| Total Contributions | 8918909 | TotalContributions |
| Total Program Service Revenue | 0 | TotalProgramServiceRevenue |
Investment Income InvestmentIncome
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 36484 | TotalRevenueColumn |
| Exclusion | $36,484 | ExclusionAmount |
Income From Invest Bond Proceeds IncomeFromInvestBondProceeds
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 0 | TotalRevenueColumn |
Royalties Revenue RoyaltiesRevenue
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 0 | TotalRevenueColumn |
Net Gain Or Loss Investments NetGainOrLossInvestments
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 0 | TotalRevenueColumn |
Net Income From Fundraising Events NetIncomeFromFundraisingEvents
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 0 | TotalRevenueColumn |
Net Income From Gaming NetIncomeFromGaming
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 0 | TotalRevenueColumn |
Net Income Or Loss NetIncomeOrLoss
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 0 | TotalRevenueColumn |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Other Revenue | 0 | TotalOtherRevenue |
Total Revenue TotalRevenue
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 8955393 | TotalRevenueColumn |
| Exclusion | $36,484 | ExclusionAmount |
Grants To Domestic Orgs GrantsToDomesticOrgs
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 4259390 | Total |
| Program Services | 4259390 | ProgramServices |
Grants To Domestic Individuals GrantsToDomesticIndividuals
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Foreign Grants ForeignGrants
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Benefits To Members BenefitsToMembers
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Comp Current Officers Directors CompCurrentOfficersDirectors
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 617000 | Total |
| Management And General | 61700 | ManagementAndGeneral |
| Fundraising | 555300 | Fundraising |
Comp Disqual Persons CompDisqualPersons
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Other Salaries And Wages OtherSalariesAndWages
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 329659 | Total |
| Management And General | 32966 | ManagementAndGeneral |
| Fundraising | 296693 | Fundraising |
Pension Plan Contributions PensionPlanContributions
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Other Employee Benefits OtherEmployeeBenefits
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 147812 | Total |
| Management And General | 14781 | ManagementAndGeneral |
| Fundraising | 133031 | Fundraising |
Payroll Taxes PayrollTaxes
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Fees For Services Management FeesForServicesManagement
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 113712 | Total |
| Management And General | 113712 | ManagementAndGeneral |
| Fundraising | 0 | Fundraising |
Fees For Services Legal FeesForServicesLegal
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 5335 | Total |
| Management And General | 5335 | ManagementAndGeneral |
| Fundraising | 0 | Fundraising |
Fees For Services Accounting FeesForServicesAccounting
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Fees For Services Lobbying FeesForServicesLobbying
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Fees For Services Prof Fundraising FeesForServicesProfFundraising
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Fees For Services Invst Mgmnt Fees FeesForServicesInvstMgmntFees
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Fees For Services Other FeesForServicesOther
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 15151 | Total |
| Management And General | 15151 | ManagementAndGeneral |
| Fundraising | 0 | Fundraising |
Advertising Advertising
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 33081 | Total |
| Management And General | 3308 | ManagementAndGeneral |
| Fundraising | 29773 | Fundraising |
Office Expenses OfficeExpenses
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 149787 | Total |
| Management And General | 14979 | ManagementAndGeneral |
| Fundraising | 134808 | Fundraising |
Information Technology InformationTechnology
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Royalties Royalties
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Occupancy Occupancy
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 74383 | Total |
| Management And General | 7438 | ManagementAndGeneral |
| Fundraising | 66945 | Fundraising |
Travel Travel
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 31855 | Total |
| Management And General | 0 | ManagementAndGeneral |
| Fundraising | 31855 | Fundraising |
Travel Entrtnmnt Public Officials TravelEntrtnmntPublicOfficials
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Conferences Meetings ConferencesMeetings
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 84272 | Total |
| Management And General | 42136 | ManagementAndGeneral |
| Fundraising | 42136 | Fundraising |
Interest Interest
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Payments To Affiliates PaymentsToAffiliates
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Depreciation Depletion DepreciationDepletion
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 18112 | Total |
| Management And General | 18112 | ManagementAndGeneral |
| Fundraising | 0 | Fundraising |
Insurance Insurance
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 0 | Total |
Other Expenses OtherExpenses (2 entries)
| DescriptionDescription | TotalTotal | Management And GeneralManagementAndGeneral | FundraisingFundraising |
|---|---|---|---|
| SEMINARS AND EDUCATION | 5393 | 539 | 4854 |
| DUES AND SUBSCRIPTIONS | 3170 | 0 | 3170 |
Total Functional Expenses TotalFunctionalExpenses
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 5888112 | Total |
| Program Services | 4259390 | ProgramServices |
| Management And General | 330157 | ManagementAndGeneral |
| Fundraising | 1298565 | Fundraising |
Savings And Temp Cash Investments SavingsAndTempCashInvestments
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 4985857 | BOY |
| EOY | 5732940 | EOY |
Pledges And Grants Receivable PledgesAndGrantsReceivable
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 2227657 | BOY |
| EOY | 4362848 | EOY |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Accounts Receivable | AccountsReceivable |
Prepaid Expenses Deferred Charges PrepaidExpensesDeferredCharges
| Field | Value | IRS element (for citing) |
|---|---|---|
| EOY | 13833 | EOY |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Land Buildings Equipment Basis | 168169 | LandBuildingsEquipmentBasis |
| Land Bldg Equipment Accum Deprec | 153594 | LandBldgEquipmentAccumDeprec |
Land Buildings Equipment Basis Net LandBuildingsEquipmentBasisNet
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 32687 | BOY |
| EOY | 14575 | EOY |
Investments Pub Traded Securities InvestmentsPubTradedSecurities
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 285972 | BOY |
| EOY | 68117 | EOY |
Investments Other Securities InvestmentsOtherSecurities
| Field | Value | IRS element (for citing) |
|---|---|---|
| EOY | 67964 | EOY |
Other Assets Total OtherAssetsTotal
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 10870 | BOY |
| EOY | 6865 | EOY |
Total Assets TotalAssets
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 7543043 | BOY |
| EOY | 10267142 | EOY |
Accounts Payable Accrued Expenses AccountsPayableAccruedExpenses
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 66121 | BOY |
| EOY | 83573 | EOY |
Other Liabilities OtherLiabilities
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 303370 | BOY |
| EOY | 702075 | EOY |
Total Liabilities TotalLiabilities
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 369491 | BOY |
| EOY | 785648 | EOY |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Follow SFAS117 | X | FollowSFAS117 |
Unrestricted Net Assets UnrestrictedNetAssets
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 1716947 | BOY |
| EOY | 580912 | EOY |
Temporarily Restricted Net Assets TemporarilyRestrictedNetAssets
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 5394512 | BOY |
| EOY | 8838489 | EOY |
Permanently Restricted Net Assets PermanentlyRestrictedNetAssets
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 62093 | BOY |
| EOY | 62093 | EOY |
Total Net Assets Fund Balances TotalNetAssetsFundBalances
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 7173552 | BOY |
| EOY | 9481494 | EOY |
Total Liab Net Assets Fund Balances TotalLiabNetAssetsFundBalances
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 7543043 | BOY |
| EOY | 10267142 | EOY |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Method Of Accounting Accrual | X | MethodOfAccountingAccrual |
| Accountant Compile Or Review | false | AccountantCompileOrReview |
| FS Audited | true | FSAudited |
| Audit Committee | true | AuditCommittee |
| Financial Statement Consolidated | X | FinancialStatementConsolidated |
| Federal Grant Audit Required | false | FederalGrantAuditRequired |
Schedule A IRS990ScheduleA
| Field | Value | IRS element (for citing) |
|---|---|---|
| Publicly Supported Org170b1 Avi | X | PubliclySupportedOrg170b1Avi |
Gifts Grants Contrib Received170 GiftsGrantsContribReceived170
| Field | Value | IRS element (for citing) |
|---|---|---|
| Current Tax Year Minus4 Years | 10836405 | CurrentTaxYearMinus4Years |
| Current Tax Year Minus3 Years | 4804855 | CurrentTaxYearMinus3Years |
| Current Tax Year Minus2 Years | 5598863 | CurrentTaxYearMinus2Years |
| Current Tax Year Minus1 Year | 4359865 | CurrentTaxYearMinus1Year |
| Current Tax Year | 721605 | CurrentTaxYear |
| Total | 26321593 | Total |
Total170 Total170
| Field | Value | IRS element (for citing) |
|---|---|---|
| Current Tax Year Minus4 Years | 10836405 | CurrentTaxYearMinus4Years |
| Current Tax Year Minus3 Years | 4804855 | CurrentTaxYearMinus3Years |
| Current Tax Year Minus2 Years | 5598863 | CurrentTaxYearMinus2Years |
| Current Tax Year Minus1 Year | 4359865 | CurrentTaxYearMinus1Year |
| Current Tax Year | 721605 | CurrentTaxYear |
| Total | 26321593 | Total |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Amounts Subst Contributors Total | 9891364 | AmountsSubstContributorsTotal |
| Public Support Total170 | 16430229 | PublicSupportTotal170 |
Gross Investment Income170 GrossInvestmentIncome170
| Field | Value | IRS element (for citing) |
|---|---|---|
| Current Tax Year Minus4 Years | 175433 | CurrentTaxYearMinus4Years |
| Current Tax Year Minus3 Years | 250673 | CurrentTaxYearMinus3Years |
| Current Tax Year Minus2 Years | 188867 | CurrentTaxYearMinus2Years |
| Current Tax Year Minus1 Year | 74077 | CurrentTaxYearMinus1Year |
| Current Tax Year | 33934 | CurrentTaxYear |
| Total | 722984 | Total |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Support | 27044577 | TotalSupport |
| Public Support Pertcentage170 | 0.60752 | PublicSupportPertcentage170 |
| Public Support Pertcent Prior Year | 0.63509 | PublicSupportPertcentPriorYear |
| Thirty Three Percnt Tests CY170 | X | ThirtyThreePercntTestsCY170 |
Schedule B IRS990ScheduleB
Contributor Info ContributorInfo
| Field | Value | IRS element (for citing) |
|---|---|---|
| Contributor Number | RESTRICTED | ContributorNumber |
Contributor Name Business ContributorNameBusiness
| Field | Value | IRS element (for citing) |
|---|---|---|
| Business Name Line1 | RESTRICTED | BusinessNameLine1 |
Contributor Address US ContributorAddressUS
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | RESTRICTED | AddressLine1 |
| Address Line2 | RESTRICTED | AddressLine2 |
| City | RESTRICTED | City |
| State | RESTRICTED | State |
| ZIP Code | RESTRICTED | ZIPCode |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Aggregate Contributions | RESTRICTED | AggregateContributions |
Schedule D IRS990ScheduleD
| Field | Value | IRS element (for citing) |
|---|---|---|
| Art Public Exhibition Amts | ArtPublicExhibitionAmts | |
| Held Works Of Art Amts | HeldWorksOfArtAmts |
Current Year CurrentYear
| Field | Value | IRS element (for citing) |
|---|---|---|
| Beginning Of Year Balance | 62093 | BeginningOfYearBalance |
| Investment Earnings Or Losses | 7353 | InvestmentEarningsOrLosses |
| Other Expenditures | 7353 | OtherExpenditures |
| End Of Year Balance | 62093 | EndOfYearBalance |
Current Year Minus1 Year CurrentYearMinus1Year
| Field | Value | IRS element (for citing) |
|---|---|---|
| Beginning Of Year Balance | 62093 | BeginningOfYearBalance |
| Investment Earnings Or Losses | 6606 | InvestmentEarningsOrLosses |
| Other Expenditures | 6606 | OtherExpenditures |
| End Of Year Balance | 62093 | EndOfYearBalance |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Permanent Endowment EOY Balance | 1.00000 | PermanentEndowmentEOYBalance |
| Endowments Held By Unrelated Orgs | false | EndowmentsHeldByUnrelatedOrgs |
| Endowments Held By Related Orgs | true | EndowmentsHeldByRelatedOrgs |
| Are Related Orgs Listed Schedule R | true | AreRelatedOrgsListedScheduleR |
| Land | Land | |
| Buildings | Buildings |
Leasehold Improvements LeaseholdImprovements
| Field | Value | IRS element (for citing) |
|---|---|---|
| Other Cost Or Other Basis | 11053 | OtherCostOrOtherBasis |
| Depreciation | 11053 | Depreciation |
| Book Value | 0 | BookValue |
Equipment Equipment
| Field | Value | IRS element (for citing) |
|---|---|---|
| Other Cost Or Other Basis | 40791 | OtherCostOrOtherBasis |
| Depreciation | 40791 | Depreciation |
| Book Value | 0 | BookValue |
Other Land Buildings OtherLandBuildings
| Field | Value | IRS element (for citing) |
|---|---|---|
| Other Cost Or Other Basis | 116325 | OtherCostOrOtherBasis |
| Depreciation | 101750 | Depreciation |
| Book Value | 14575 | BookValue |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Of Book Value Land Buildings | 14575 | TotalOfBookValueLandBuildings |
| Federal Income Tax Liability | 0 | FederalIncomeTaxLiability |
Other Liabilities OtherLiabilities
| Field | Value | IRS element (for citing) |
|---|---|---|
| Description | DUE TO/FROM TGEN | Description |
| Amount | $702,075 | Amount |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Of Amounts | 702075 | TotalOfAmounts |
Form990 Schedule D Part XIV Form990ScheduleDPartXIV (2 entries)
| IdentifierIdentifier | Return ReferenceReturnReference | ExplanationExplanation |
|---|---|---|
| SCHEDULE D, PART V | SUPPLEMENTAL INFORMATION - ENDOWMENTS | THE INSTITUTE'S POLICY FOR APPROPRIATING THE DISTRIBUTION OF ITS SUMMER INTERNSHIP PROGRAM ENDOWMENT HAS BEEN DESIGNED TO SUPPORT A SPECIFIC NUMBER OF SUMMER INTERNS EACH YEAR FOR THE NEXT 25 YEARS. THE INSTITUTE CONSIDERED THE LONG-TERM EXPECTED RETURN ON ITS ENDOWMENT. THE INSTITUTE CLASSIFIES AS PERMANENTLY RESTRICTED NET ASSETS (1) THE ORIGINAL VALUE OF THE GIFT DONATED TO THE PERMANENT ENDOWMENT, (2) THE ORIGINAL VALUE OF SUBSEQUENT GIFTS TO THE PERMANENT ENDOWMENT, AND (3) ACCUMULATIONS TO THE PERMANENT ENDOWMENT MADE IN ACCORDANCE WITH THE DIRECTION OF THE APPLICABLE DONOR GIFT INSTRUMENT. |
| SCHEDULE D, PART X - FIN 48 FOOTNOTE | IN FISCAL 2009, THE INSTITUTE ADOPTED A "MORE LIKELY THAN NOT" THRESHOLD FOR FINANCIAL STATEMENT RECOGNITION AND MEASUREMENT OF AN UNCERTAIN TAX POSITION TAKEN OR EXPECTED TO BE TAKEN IN A TAX RETURN. THE INSTITUTE RECOGNIZES INTEREST AND PENALTIES RELATED TO UNCERTAIN TAX POSITIONS IN OTHER EXPENSES, IF THEY EXIST. THE ADOPTION OF THE MORE LIKELY THAN NOT THRESHOLD FOR FINANCIAL STATEMENT RECOGNITION AND MEASUREMENT OF UNCERTAIN TAX POSITIONS HAD NO SIGNIFICANT IMPACT ON THE INSTITUTE'S CONSOLIDATED FINANCIAL STATEMENTS FOR THE YEARS ENDED JUNE 30, 2010 AND 2009. |
Schedule I IRS990ScheduleI
| Field | Value | IRS element (for citing) |
|---|---|---|
| Records Maintained | true | RecordsMaintained |
Recipient Table RecipientTable
Recipient Name Business RecipientNameBusiness
| Field | Value | IRS element (for citing) |
|---|---|---|
| Business Name Line1 | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE | BusinessNameLine1 |
Address US AddressUS
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | 445 N 5TH STREET SUITE 600 | AddressLine1 |
| City | PHOENIX | City |
| State | AZ | State |
| ZIP Code | 85004 | ZIPCode |
| Field | Value | IRS element (for citing) |
|---|---|---|
| EIN Of Recipient | 753065445 | EINOfRecipient |
| IRC Section | 501(C)(3) | IRCSection |
| Amount Of Cash Grant | 4259390 | AmountOfCashGrant |
| Purpose Of Grant | SUPPORT GENOMICS RESEARCH | PurposeOfGrant |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Nbr Of501 C3 And Govt Grants | 1 | TotalNbrOf501C3AndGovtGrants |
| Total Nbr Of Other Organizations | 0 | TotalNbrOfOtherOrganizations |
Form990 Schedule I Part IV Form990ScheduleIPartIV
| Field | Value | IRS element (for citing) |
|---|---|---|
| Identifier | SCHEDULE I, PART I, LINE 2 | Identifier |
| Return Reference | PROCESS FOR MONITORING USE OF GRANT FUNDS IN THE U.S. | ReturnReference |
| Explanation | THE FOUNDATION IS ORGANIZED EXCLUSIVELY TO BENEFIT TGEN, A RELATED 501(C)(3) TAX-EXEMPT ORGANIZATION, BY SUPPORTING TGEN'S FUNDRAISING AND DEVELOPMENT FUNCTIONS. | Explanation |
Schedule J IRS990ScheduleJ
| Field | Value | IRS element (for citing) |
|---|---|---|
| First Class Or Charter Travel | X | FirstClassOrCharterTravel |
| Club Dues Or Fees | X | ClubDuesOrFees |
| Written Policy Re T And E Expenses | true | WrittenPolicyReTAndEExpenses |
| Substantiation Required | true | SubstantiationRequired |
| Compensation Committee | X | CompensationCommittee |
| Independent Consultant | X | IndependentConsultant |
| Compensation Survey | X | CompensationSurvey |
| Board Or Committee Approval | X | BoardOrCommitteeApproval |
| Severance Payment | false | SeverancePayment |
| Supplemental Nonqual Retire Plan | false | SupplementalNonqualRetirePlan |
| Equity Based Comp Arrangement | false | EquityBasedCompArrangement |
| Comp Based On Revenue Of Filing Org | false | CompBasedOnRevenueOfFilingOrg |
| Comp Based On Revenue Related Orgs | false | CompBasedOnRevenueRelatedOrgs |
| Comp Based Net Earnings Filing Org | false | CompBasedNetEarningsFilingOrg |
| Comp Based Net Earnings Relate Orgs | false | CompBasedNetEarningsRelateOrgs |
| Any Non Fixed Payments | false | AnyNonFixedPayments |
| Initial Contract Exception | false | InitialContractException |
Form990 Schedule J Part II Form990ScheduleJPartII (4 entries)
| Base Compensation Filing OrgBaseCompensationFilingOrg | Comp Based On Related OrgsCompBasedOnRelatedOrgs | Bonus Filing OrgBonusFilingOrg | Bonus Related OrgsBonusRelatedOrgs | Other Compensation Filing OrgOtherCompensationFilingOrg | Other Compensation Related OrgsOtherCompensationRelatedOrgs | Deferred Comp Filing OrgDeferredCompFilingOrg | Deferred Comp Related OrgsDeferredCompRelatedOrgs | Nontaxable Benefits Filing OrgNontaxableBenefitsFilingOrg | Nontaxable Benefits Related OrgsNontaxableBenefitsRelatedOrgs | Total Compensation Filing OrgTotalCompensationFilingOrg | Total Compensation Related OrgsTotalCompensationRelatedOrgs | Comp Report Prior990 Filing OrgCompReportPrior990FilingOrg | Comp Report Prior990 Related OrgsCompReportPrior990RelatedOrgs |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MICHAEL BASSOFF | |||||||||||||
| 0 | 415239 | 0 | 0 | 0 | 22000 | 0 | 9800 | 0 | 5991 | 0 | 453030 | 0 | 0 |
| DENISE MCCLINTIC | |||||||||||||
| 0 | 159098 | 0 | 0 | 0 | 7864 | 0 | 6292 | 0 | 3779 | 0 | 177033 | 0 | 0 |
| JEFFREY M TRENT PHD | |||||||||||||
| 0 | 746703 | 0 | 232685 | 0 | 66658 | 0 | 9800 | 0 | 7753 | 0 | 1063599 | 0 | 0 |
| TERESA BURLESON | |||||||||||||
| 0 | 334354 | 0 | 24276 | 0 | 16500 | 0 | 9800 | 0 | 7753 | 0 | 392683 | 0 | 0 |
Form990 Schedule J Part III Form990ScheduleJPartIII (2 entries)
| IdentifierIdentifier | ExplanationExplanation |
|---|---|
| SCHEDULE J, PART I, LINE 1A | FIRST CLASS TRAVEL IS PERMITTED BY EXECUTIVE STAFF ONLY AND MUST, PER TGEN POLICY, BE PRE-APPROVED BY THE CHIEF OPERATING OFFICER. TGEN DOES PROVIDE MEMBERSHIP TO DR. TRENT AT THE PARADISE VALLEY COUNTRY CLUB. THIS EXPENSE WAS PRE-APPROVED BY THE CHIEF OPERATING OFFICER. THESE EXPENSES WERE NOT CONSIDERED AS TAXABLE COMPENSATION TO THE RECIPIENT. |
| SCHEDULE J, PART I, LINE 7 | SOME OF THE PERSONS LISTED IN FORM 990, PART VII WERE PAID BONUSES WHICH WERE BASED ON ACCOMPLISHMENTS OF SPECIFIC MILESTONES AND/OR PERFORMANCE BASES. |
Schedule O IRS990ScheduleO
General Explanation GeneralExplanation (12 entries)
| IdentifierIdentifier | Return ReferenceReturnReference | ExplanationExplanation |
|---|---|---|
| FORM 990, PART III, LINE 4 | PROGRAM SERVICE ACCOMPLISHMENTS | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE FOUNDATION RAISES FUNDS FOR THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN). THE PROGRAM SERVICE ACCOMPLISHMENTS OF TGEN ARE LISTED BELOW: INTRODUCTION TGEN RESEARCH MOVED FORWARD IN FY10 AT A PACE FAR GREATER THAN ANY PREVIOUS YEAR. THIS NARRATIVE PROVIDES AN OVERVIEW OF THESE SUCCESSES AND REINFORCES OUR MISSION OF DETERMINING THE ROOT GENETIC CAUSES OF NUMEROUS DISEASES AND DISORDERS AND THEN CONVERTING THAT KNOWLEDGE AS QUICKLY AS POSSIBLE INTO DIAGNOSTIC TESTS AND THERAPEUTICS FOR IMPROVED PATIENT CARE. OUR RESEARCH COLLABORATIONS WERE MANY AND VARIED IN TERMS OF BREADTH AND SCOPE AND LOCATION - MANY LOCALLY, OTHERS NATIONALLY AND GLOBALLY. LOCALLY, OUR COLLABORATIONS WITH BANNER HEALTH, MAYO CLINIC, SCOTTSDALE HEALTHCARE, BANNER RESEARCH INSITUTE AND OTHER HOSPITALS AND HEALTH CARE PROVIDERS FOCUSED ON NUMEROUS TYPES OF CANCER, NEUROLOGIC IMPAIRMENTS, AND METABOLIC DISORDERS. TGEN'S RESEARCH HAD A PRESENCE ACROSS THE STATE. THIS INCLUDED OUR ONGOING EFFORTS TO ASSIST THE ARIZONA DEPARTMENT OF HEALTH SERVICES (ADHS) WITH STATE-OF-THE-ART TESTING FOR THE H1N1 SWINE FLU, LOOKING FOR WAYS TO HELP TRACK DRUG-RESISTANT MUTATIONS, FIND NEW TREATMENTS AND AVOID A PANDEMIC. TGEN FACULTY PRESENTED DETAILS ABOUT TGEN'S TEST IN EARLY NOVEMBER 2009 AT THE 47TH ANNUAL MEETING OF THE INFECTIOUS DISEASES SOCIETY OF AMERICA (IDSA) IN PHILADELPHIA. THE H1N1 WORK OCCURRED IN OUR FLAGSTAFF FACILITY, TGEN NORTH, WHILE TO THE SOUTH, TGEN AND THE UNIVERSITY OF ARIZONA ESTABLISHED THE SOUTHWEST COMPREHENSIVE CENTER FOR DRUG DISCOVERY AND DEVELOPMENT THROUGH A $7.5 MILLION NIH GRANT. THE NEW CENTER WILL ALLEVIATE BOTTLENECKS THAT EXIST BETWEEN THE LABORATORY-BASED DISCOVERY OF PROMISING THERAPEUTIC TARGETS AND THE ULTIMATE GOAL OF DELIVERING NEW, SAFE AND EFFECTIVE DRUGS TO ADDRESS UNMET MEDICAL NEEDS OF THE PATIENT. LOCALLY, TGEN'S WORK WITH ASU INCLUDED THE PARTNERSHIP FOR PERSONALIZED MEDICINE, WHICH CONTINUED TO DEVELOP A ROBUST PROTEOMICS APPROACH TO MEDICINE AND HEALTH CARE, AND BUILDING OUT A SUPERCOMPUTER INFRASTRUCTURE THAT RANKS AMONG THE FASTEST IN THE BIOMEDICAL SCIENCES. IN EARLY FEBRUARY 2010, TGEN ANNOUNCED THE COMPLETION OF A STRATEGIC ALLIANCE AND AFFILIATION AGREEMENT WITH THE VAN ANDEL RESEARCH INSTITUTE (VARI) THAT WILL MAXIMIZE THE RESEARCH CAPABILITIES OF BOTH NON-PROFIT INSTITUTES. TGEN EXPECTS THE AGREEMENT TO CREATE A ROBUST BASIC-SCIENCE-TO-TRANSLATIONAL DELIVERY PLATFORM AIMED AT DEVELOPING NEW TESTS AND TREATMENTS FOR PATIENT BENEFIT. TGEN'S FINAL CONTRACT REVISION, SIGNED JANUARY 15, ENABLED THE ARIZONA BIOMEDICAL RESEARCH COMMISSION (ABRC) TO CONTINUE FUNDING TGEN THROUGH STATE TOBACCO-TAX REVENUES. THE NEW STATE CONTRACT, FACILITATED THROUGH ABRC LEADERSHIP AND THE ARIZONA ATTORNEY GENERAL'S OFFICE, ENSURES CONTINUED STATE FUNDING THROUGH FISCAL YEAR 2012. TGEN, THROUGH ITS AFFILIATION WITH SCOTTSDALE HEALTHCARE, INITIATED A NUMBER OF CLINICAL TRIALS FOCUSED ON NUMEROUS TYPES OF CANCER. CLINICAL TRIALS DETERMINE THE ACTIONS OF DRUGS IN HUMANS BY IDENTIFYING THE SIDE EFFECTS ASSOCIATED WITH INCREASING DOSES AND PROVIDING EVIDENCE OF EFFECTIVENESS. IN SEPTEMBER 2009, TGEN PUBLISHED ITS SECOND INDEPENDENT, THIRD PARTY ECONOMIC IMPACT REPORT, WHICH PROVIDED ENCOURAGING RESULTS IN TERMS OF TGEN AS A POSITIVE RETURN ON THE STATE INVESTMENT. WE FOLLOWED THAT REPORT IN JANUARY 2010 WITH THE PUBLICATION OF OUR FIRST INDEPENDENT ANALYSIS OF THE ECONOMIC IMPACT OF TGEN DRUG DEVELOPMENT (TD2) ON EMPLOYMENT, REVENUES AND BUSINESS DEVELOPMENT IN SCOTTSDALE. ADDITIONALLY, A DESCRIPTION OF PEER REVIEWED PUBLICATION, GRANT, CONTRACT, PHILANTHROPIC, EDUCATIONAL AND MEDIA ACTIVITY FOLLOWS. PEER-REVIEWED LABORATORY RESEARCH PUBLICATIONS AND PRESENTATIONS SINCE ITS INCEPTION, THE RESEARCH AND CLINICAL ASPECTS OF TGEN HAVE FOCUSED SOLELY ON THE PATIENT AS AN END POINT. AT TGEN, OUR FACULTY WORK TO DISCOVER THE UNDERLYING CAUSE OF DISEASE PROGRESSION AND RESISTANCE TO THERAPY AND WHY SOME INDIVIDUALS ENCOUNTER DEBILITATING DISEASES AND OTHERS LIVE HEALTHY LIVES. OUR CLINICAL TRIALS -IN COLLABORATION WITH SCOTTSDALE HEALTHCARE- NOT ONLY OFFER HOPE TO PATIENTS SUFFERING FROM MANY TYPES OF CANCER, THE RESULTS SERVE TO INFORM OUR RESEARCH STUDIES. SUPPORTED BY A NEW WAVE OF TECHNOLOGY, TGEN'S RESEARCH AND CLINICAL EFFORTS REMAIN EQUAL TO THE STRENGTHS AND CAPABILITIES OF ANY OF TODAY'S LEADING RESEARCH AND CLINICAL INSTITUTES. NOWHERE IS THIS MORE EVIDENT THAN WITH TGEN'S SEQUENCING CAPABILITIES. TGEN HAS "CENTER OF EXCELLENCE" STATUS WITH THREE OF THE WORLD'S LARGEST GENOMICS TECHNOLOGY PROVIDERS - AFFYMETRIX, AGILENT AND LIFE TECHNOLOGIES. TGEN'S NEXT-GENERATION OR "NEXT-GEN" SEQUENCING, SYSTEMS ALLOW US TO DIG DEEPER INTO THE GENOME THAN EVER BEFORE BY PROVIDING MORE INFORMATION AND INCREASING OUR PROBABILITY OF IDENTIFYING SOMETHING SIGNIFICANT. THE LONG-TERM HOPE IS THAT DOCTORS WILL LEVERAGE THIS INFORMATION TO INFORM DECISIONS ABOUT PATIENT CARE. A MAJOR INITIATIVE CENTERS ON CANINE GENETICS. THE PROGRAM FOR CANINE HEALTH AND PERFORMANCE (PCHP) IS A TGEN/VARI INTER-INSTITUTIONAL PROGRAM DEVELOPED TO ACCELERATE THE PATH TO DISCOVERY OF CAUSATIVE GENETIC LESIONS ACROSS SEVERAL DISEASES IN DOGS THAT SIMILARLY AFFLICT HUMANKIND (INCLUDING CANCER, DEAFNESS, MULTIPLE SCLEROSIS, HEART DEFECTS, OBESITY, NEUROLOGIC DISORDERS AND OTHERS). AN IMPORTANT PART OF THE PCHP IS THE CANINE HEREDITARY CANCER CONSORTIUM (CHCC), WHICH WAS A RECENTLY FUNDED AARA NATIONAL CANCER INSTITUTE AWARD TO TGEN. TGEN, THE VAN ANDEL RESEARCH INSTITUTE (VARI) AND THE NATIONAL CANCER INSTITUTE LAUNCHED THE CHCC TO STUDY NATURALLY OCCURRING CANCERS IN DOGS TO BETTER UNDERSTAND WHY BOTH PETS AND PEOPLE GET SICK. TGEN'S RESEARCH RESULTS APPEAR IN A NUMBER OF SCIENTIFIC AND MEDICAL JOURNALS, AND ADD TO THE GROWING KNOWLEDGE BASE OF MOLECULAR RESEARCH AND MEDICINE. IN FY10, TGEN RESEARCHERS PUBLISHED THEIR RESEARCH RESULTS IN NUMEROUS SCHOLARLY PEER-REVIEWED ACADEMIC JOURNALS AND THROUGH PRESENTATIONS AT LEADING NATIONAL AND INTERNATIONAL CONFERENCES. THESE INCLUDE PUBLICATION IN LEADING SCIENTIFIC JOURNALS SUCH AS NEW ENGLAND JOURNAL OF MEDICINE, NATURE GENETICS, PLOS, BLOOD, CANCER RESEARCH, AND A HOST OF OTHER DISEASE-ASSOCIATED PUBLICATIONS (E.G. DIABETES, MOLECULAR CANCER THERAPEUTICS, NEUROLOGY, JOURNAL OF WOMEN'S HEALTH, ETC.) |
| SELECT HIGHLIGHTS FOR FY10 | 1. TGEN AND UC BERKELEY RESEARCHERS REPORTED IN THE JULY 20 NATURE GENETICS IDENTIFICATION OF A GENE VARIANT THAT CARRIES NEARLY TWICE THE RISK OF DEVELOPING AN INCREASINGLY COMMON TYPE OF BLOOD CANCER. INVESTIGATORS FOUND THAT MUTATIONS IN A GENE CALLED C6ORF15, OR STG, ARE ASSOCIATED WITH THE RISK OF DEVELOPING FOLLICULAR LYMPHOMA. THIS IS A CANCER OF THE BODY'S DISEASE-FIGHTING NETWORK WHOSE RATES HAVE NEARLY DOUBLED IN THE PAST THREE DECADES. CITATION: GENETIC VARIANTS AT 6P21.33 INFLUENCE FOLLICULAR LYMPHOMA RISK CHRISTINE F. SKIBOLA, PAIGE M. BRACCI, ERAN HALPERIN, LUCIA CONDE, DAVID W. CRAIG, LUZ AGANA, KELLY IYADURAI, NIKOLAUS BECKER, ANGELA BROOKES-WILSON, JOHN D. CURRY, JOHN SPINELLI, ELIZABETH A. HOLLY, JACQUES RIBY, LUOPING ZHANG, ALEXANDRA NIETERS, MARTYN T. SMITH, KEVIN M. BROWN. NATURE GENETICS 41, 873-875 (20 JULY 2009) 2. ANALYSES OF CLINICAL TRIAL RESULTS, PUBLISHED SEPTEMBER 2 IN THE NEW ENGLAND JOURNAL OF MEDICINE, SHOW A POTENTIAL NEW INVESTIGATIONAL THERAPY FOR ADVANCED AND METASTATIC BASAL CELL SKIN CANCER. THE STUDY, CONDUCTED AT TGEN CLINICAL RESEARCH SERVICE (TCRS) AT SCOTTSDALE HEALTHCARE AND TWO OTHER SITES APPEARS TO DEMONSTRATE TUMOR SHRINKAGE AND LIMITED SIDE EFFECTS. THESE FINDINGS ARE SIGNIFICANT BECAUSE NO PROVEN THERAPY EXISTS FOR ADVANCED BASAL CELL CARCINOMA (BCC). BCC IS THE MOST COMMON CANCER IN THE UNITED STATES WITH ABOUT ONE MILLION NEW CASES DIAGNOSED EACH YEAR. ARIZONA HAS ONE OF THE HIGHEST INCIDENCES OF SKIN CANCER IN THE WORLD. CITATION: INHIBITION OF THE HEDGEHOG PATHWAY IN ADVANCED BASAL-CELL CARCINOMA DANIEL D. VON HOFF, M.D., PATRICIA M. LORUSSO, D.O., CHARLES M. RUDIN, M.D., PH.D., JOSINA C. REDDY, M.D., PH.D., ROBERT L. YAUCH, PH.D., RAOUL TIBES, M.D., GLEN J. WEISS, M.D., MITESH J. BORAD, M.D., CHRISTINE L. HANN, M.D., PH.D., JULIE R. BRAHMER, M.D., HOWARD M. MACKEY, PH.D., BERTRAM L. LUM, PHARM.D., WALTER C. DARBONNE, M.S., JAMES C. MARSTERS, JR., PH.D., FREDERIC J. DE SAUVAGE, PH.D., AND JENNIFER A. LOW, M.D., PH.D. PUBLISHED AT WWW.NEJM.ORG SEPT. 2, 2009 3. TGEN CLINICAL RESEARCH SERVICES AT SCOTTSDALE HEALTHCARE ANNOUNCED SEPTEMBER 22 THE START OF A CLINICAL TRIAL FOR A DRUG DESIGNED TO COMBAT ADRENOCORTICAL CARCINOMA (ACC), A RARE BUT DEADLY CANCER THAT ATTACKS THE ADRENAL GLANDS. OTHER THAN SURGERY, THE ONLY TREATMENT FOR ACC IS THE EXACTING USE OF A COMPOUND CALLED MITOTANE, A CHEMICAL RELATIVE OF DDT, WHICH THE U.S. BANNED AS AN INSECTICIDE IN 1972. 4. DR. GLEN WEISS OF TGEN AND SCOTTSDALE HEALTHCARE IN JULY ANNOUNCED TWO SIGNIFICANT ADVANCES IN TREATING LUNG CANCER. DR. WEISS, AN ASSOCIATE INVESTIGATOR IN TGEN'S CANCER AND CELL BIOLOGY DIVISION AND DIRECTOR OF THORACIC ONCOLOGY AT TGEN CLINICAL RESEARCH SERVICES AT SCOTTSDALE HEALTHCARE, MADE BOTH ANNOUNCEMENTS AT THE 13TH WORLD CONFERENCE ON LUNG CANCER IN SAN FRANCISCO, OCTOBER 2009. 5. A SCIENTIFIC PAPER ABOUT USING MICRORNAS, SMALL MOLECULES THAT REGULATE GENE EXPRESSION IN CELLS, TO HELP UNDERSTAND AND PREDICT HOW MALIGNANT LUNG CANCER OFTEN SPREADS TO THE BRAIN. THIS PAPER WAS SELECTED AS THE BEST OF 233 SCIENTIFIC PAPERS AT THE INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS INTERNATIONAL CONFERENCE ON BIOINFORMATICS & BIOMEDICINE, HELD NOV. 1-4 IN WASHINGTON, D.C. CITATION: IDENTIFYING MIRNA AND IMAGING FEATURES ASSOCIATED WITH METASTASIS OF LUNG CANCER TO THE BRAIN - SARA NASSER, AARATI R. RANADE, SHRAVAN SRIDHART, LISA HANEY, RONALD L. KORN, MICHAEL B. GOTWAY, GLEN J. WEISS, SEUNGCHAN KIM. 6. A STUDY PUBLISHED IN THE DECEMBER EDITION OF DIABETIC MEDICINE, SHOWED IT IS POSSIBLE TO IDENTIFY BIOMARKERS ASSOCIATED WITH END-STAGE RENAL DISEASE (ESRD) FROM THE POOLED DNA OF MORE THAN 1,000 DIABETICS. SPECIFICALLY, TGEN RESEARCHERS IDENTIFIED GENES THAT COULD POTENTIALLY CONTRIBUTE TO ESRD AMONG THOSE WITH TYPE 1 DIABETES. CITATION: IDENTIFICATION OF SPECIFIC DNA VARIANTS MAY ENHANCE OUR UNDERSTANDING OF GENETIC RISK FACTORS FOR RENAL DISEASE AND MAY PROVIDE DIAGNOSTIC VALUE IN DETERMINING WHICH PATIENTS ARE AT GREATEST RISK OF DEVELOPING ESRD - DAVID W. CRAIG, MEREDITH P. MILLIS AND JOHANNA K. DISTEFANO. 7. AS PART OF AN OVERALL EFFORT BY THE NATIONAL INSTITUTES OF HEALTH TO IDENTIFY ALL MICROBIOMS ON AND IN THE HUMAN BODY, TGEN CONDUCTED A STUDY IN CONJUNCTION WITH JOHNS HOPKINS UNIVERSITY PUBLISHED JAN. 6 BY THE SCIENTIFIC JOURNAL PLOS ONE, WHICH DOCUMENTED FOR THE FIRST TIME THE DRAMATIC CHANGES IN BACTERIAL COMMUNITIES FOLLOWING CIRCUMCISION AND THE POSSIBLE EFFECTS ON HIV INFECTION. CITATION: THE EFFECTS OF CIRCUMCISION ON THE PENIS MICROBIOME - LANCE B. PRICE, CINDY M. LIU, KRISTINE E. JOHNSON, MALIHA AZIZ, MATTHEW K. LAU, JOLENE BOWERS, JACQUES RAVEL, PAUL S. KEIM, DAVID SERWADDA, MARIA J. WAWER AND RONALD H. GRAY. 8. A STUDY IN CONJUNCTION WITH SCOTTSDALE HEALTHCARE - AND WITH THE HELP OF SCIENTISTS AT THE VAN ANDEL RESEARCH INSTITUTE - SHOWED HOW TO PREDICT WHICH PATIENTS WITH SMALL-CELL LUNG CANCER MAY BE RESISTANT TO FIRST-LINE CHEMOTHERAPY. THIS STUDY WAS PRESENTED IN JANUARY IN SAN DIEGO AT THE AACR-IASLC'S JOINT CONFERENCE ON MOLECULAR ORIGINS OF LUNG CANCER. CITATION: TUMOR MICRORNA BIOMARKERS ASSOCIATED WITH DE NOVO CHEMORESISTANCE IN SMALL CELL LUNG CANCER - GLEN J. WEISS, AARATI R. RANADE, DAVID CHERBA, SHRAVAN SRIDHAR, PATRICK RICHARDSON, ANOOR PARIPATI, BRAD BOWLES AND CRAIG WEBB. 9. AS PART OF A MULTI-YEAR STUDY IN CONJUNCTION WITH THE ARIZONA ALZHEIMER'S CONSORTIUM, TGEN SCIENTISTS PUBLISHED A PAPER IN THE JANUARY EDITION OF BMC GENOMICS, SHOWING HOW THREE KINASES, OR PROTEINS, DISMANTLE CONNECTIONS WITHIN BRAIN CELLS, WHICH MAY LEAD TO MEMORY LOSS ASSOCIATED WITH ALZHEIMER'S DISEASE. CITATION: HIGH-CONTENT SIRNA SCREENING OF THE "KINOME" IDENTIFIES EIF2AK2 AND DYRK1A AS CRITICAL MEDIATORS OF AD-RELATED TAU HYPERPHOSPHORYLATION - AZORSA, ROBESON, FROST, MEECHOOVET, BRAUTIGAM, DICKEY, BEAUDRY, BASU, HOLZ, HERNANDEZ, BISANZ, GWINN, GROVER, ROGERS, REIMAN, HUTTON, STEPHAN, MOUSSES AND DUNCKLEY. 10. TGEN WAS PART OF A NATIONAL CONSORTIUM THAT CONDUCTED THE LARGEST GENOME-WIDE ASSOCIATION STUDY IN ALZHEIMER'S DISEASE TO DATE, IDENTIFYING TWO NEW GENETIC VARIANTS AND CONFIRMING TWO OTHERS. THEIR FINDINGS WERE PUBLISHED MAY 12 IN THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. CITATION: SESHADRI S, ET AL "GENOME-WIDE ANALYSIS OF GENETIC LOCI ASSOCIATED WITH ALZHEIMER DISEASE" JAMA 2010; 303: 1832-40. 11. DR. DANIEL D. VON HOFF, TGEN'S PHYSICIAN-IN-CHIEF, RECEIVED A TOP AWARD FROM THE AMERICAN SOCIETY OF CLINICAL ONCOLOGY (ASCO) FOR HIS CANCER RESEARCH. DR. VON HOFF RECEIVED THE 2010 DAVID A. KARNOFSKY MEMORIAL AWARD AND LECTURE AT ASCO'S 46TH ANNUAL MEETING THIS PAST WEEK (JUNE 4-8) AT THE MCCORMICK PLACE IN CHICAGO. ASCO PRESENTED THE AWARD TO DR. VON HOFF "FOR HIS OUTSTANDING ACHIEVEMENTS IN CANCER RESEARCH AND FOR HIS IMPACT ON THE TREATMENT OF PATIENTS WITH CANCER." CITATION: ANALYSIS OF SOMATIC COPY NUMBER ALTERATIONS ASSOCIATED WITH POOR PROGNOSIS AND PROGRESSION OF MULTIPLE MYELOMA IN AFRICAN AMERICANS. 12. TGEN SCIENTISTS HAVE IDENTIFIED FIVE GENETIC BIOMARKERS THAT COULD HELP LEAD TO IMPROVED TREATMENTS, WITH FEWER SIDE EFFECTS, FOR PATIENTS WITH DIABETES. TGEN SENIOR INVESTIGATOR DR. JOHANNA DISTEFANO PRESENTED THE FINDINGS IN NEW ORLEANS ON JUNE 6, 2010, AT THE 69TH SCIENTIFIC SESSIONS OF THE AMERICAN DIABETES ASSOCIATION. CITATION: IMPROVED INSULIN SENSITIVITY (SI), A PRIMARY RESPONSE TO THIAZOLIDINEDIONE (TZD) THERAPY, VARIES AMONG TREATED INDIVIDUALS. AMERICAN DIABETES ASSOCIATION. | |
| CLINICAL RESEARCH | ESTABLISHED IN 2006, TGEN CLINICAL RESEARCH SERVICES (TCRS), A STRATEGIC ALLIANCE WITH SCOTTSDALE HEALTHCARE (SHC), PROVIDES A DIRECT CLINICAL RESEARCH SITE FOR TGEN. TCRS BRINGS NEW CLINICAL RESEARCH INTO THE COMMUNITY, TO THOSE PATIENTS WHO WOULD OTHERWISE HAVE TO TRAVEL SOMEPLACE ELSE FOR ACCESS TO NEW THERAPIES OR PREVENTION AGENTS. THESE CLINICAL TRIALS GIVE OPTIONS THAT DID NOT EXIST BEFORE TO PHOENIX-AREA PATIENTS AS WELL AS PATIENTS FROM ALL OVER THE COUNTRY. TCRS CLINICIAN, UNDER THE DIRECTION TGEN PHYSICIAN-IN-CHIEF DR. DANIEL VON HOFF, FOCUS ON CLINICAL TRIALS WITH TARGETED AGENTS AND GENOMICS-BASED INDIVIDUALIZED THERAPY. TCRS WORKS IN COLLABORATION WITH PHYSICIANS IN THE LOCAL ARIZONA COMMUNITY AND ACROSS THE U.S. TO PROVIDE OPTIONS FOR THE CARE OF THEIR PATIENTS. TCRS SERVES AS AN INTERNATIONAL REFERRAL CENTER FOR PATIENTS FROM ANYWHERE IN THE WORLD. EVERY PATIENT WITH A PHYSICIAN REFERRAL IS WELCOME, PROVIDED THEY MEET THE REQUIREMENTS. IN SOME CASES, THE PATIENT MAY BE EVALUATED THROUGH THE NEW CLINIC, BUT RECEIVE TREATMENT FROM THEIR REFERRING PHYSICIAN. WE WORK FLEXIBLY TO ENSURE THE BEST AND MOST COMPLETE CARE FOR PATIENTS. PATIENT PARTICIPATION IN CLINICAL TRIALS AT TCRS - 125 VISITS PER MONTH - 35-45 NEW PATIENTS PER MONTH - 400-600 PATIENT SAMPLES COLLECTED PER MONTH GRANT SUPPORT GRANT FUNDING IS OFTEN THE LIFEBLOOD OF RESEARCH. IN FY09, TGEN INVESTIGATORS SUBMITTED 149 GRANTS TOTALING $160,926,066. TGEN WAS AWARDED 15 GRANTS, TOTALING $9,256,581, WITH AN ADDITIONAL 64 GRANTS PENDING AND IN REVIEWS TOTALING $54,142,798. ADDITIONALLY, TGEN RECEIVED $29,844,531 FROM PREVIOUS FY PENDING GRANTS, BRINGING THE AWARDED TOTAL FOR FY09 TO $39,101,112. TGEN'S SUCCESS RATE CURRENTLY RESTS AT 26 PERCENT OF TOTAL GRANTS SUBMITTED, PLACING THE INSTITUTE NEARLY SIX PERCENT HIGHER THAN THE NATIONAL AVERAGE (NIH OVERALL SUCCESS RATE). FY10 HIGHLIGHTS 1. A 5-YEAR NIH GRANT, TOTALING $4,059,520 TO DR. DAVID DUGGAN FOR A WECARE GENOME-WIDE ASSOCIATION STUDY OF RADIATION EXPOSURE AND BILATERAL BREAST CANCER. 2. A 2-YEAR NIH GRANT, TOTALING $1,887,446 TO DR. DUGGAN FOR FOLLOW-UP STUDIES ABOUT GENETICALLY DETERMINED RISK FACTORS FOR HIP FRACTURES. 3. A 5-YEAR NIH GRANT, TOTALING $1,532,579 TO DR. DUGGAN FOR A STUDY OF INFLAMMATION AND THROMBOSIS GENE PATHWAYS AND CARDIOVASCULAR DISEASE. 4. A 3-YEAR NIH GRANT, TOTALING $2,065,512 TO JOHN PEARSON FOR AN IN SILICO CENTER OF EXCELLENCE. 5. A 2-YEAR NIH GRANT, TOTALING $416,780, TO DR. PAUL KEIM FOR GENOMICS-BASED DIAGNOSTICS FOR COCCIDIOIDES, THE CAUSATIVE AGENTS OF VALLEY FEVER. 6. A 2-YEAR GRANT TOTALING $1,000,000 FROM THE MELANOMA RESEARCH ALLIANCE TO DR. JEFFREY TRENT FOR THE STUDY TO IDENTIFY NOVEL MELANOMA RISK GENES. 7. 3-YEAR GRANT FROM THE AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR), TOTALING $8,180,465 (A TOTAL OF NEARLY $18 MILLION WHEN INCLUDING FUNDS IN PARTNERSHIP WITH THE UNIVERSITY OF PENNSYLVANIA) TO DR. DANIEL VON HOFF TO DEVELOP REVOLUTIONARY TREATMENTS FOR PANCREATIC CANCER. 8. 2-YEAR GRANT FOR THE NATIONAL INSTITUTES OF HEALTH (NIH), TOTALING $7,551,533, TO DR. NATHALIE MEURICE AND DR. SPYRO MOUSSES TO ESTABLISH, IN CONJUNCTION WITH THE UNIVERSITY OF ARIZONA, THE SOUTHWEST COMPREHENSIVE CENTER FOR DRUG DISCOVERY AND DEVELOPMENT TO HELP TRANSFORM LABORATORY DISCOVERIES INTO NEW DRUG COMPOUNDS. 9. 2-YEAR NIH GRANT, TOTALING $4,259,456, TO DR. JEFFREY TRENT TO START, IN CONJUNCTION WITH THE VAN ANDEL RESEARCH INSTITUTE, THE CANINE HEREDITARY CANCER CONSORTIUM, WHICH WILL USE STUDIES OF DOGS TO HELP DISCOVER NEW TREATMENTS FOR RARE CANCERS IN BOTH HUMANS AND DOGS. 10. 2-YEAR NIH GRANT, TOTALING $3,576,502, TO DR. DAVID DUGGAN FOR A GENOME-WIDE ASSOCIATION STUDY TO HELP IDENTIFY THE GENETIC ORIGINS OF ARTHRITIS OF THE KNEE. 11. 2-YEAR GRANT FROM THE U.S. DEPARTMENT OF DEFENSE AND THE TELEMEDICINE & ADVANCED TECHNOLOGY RESEARCH CENTER, TOTALING $1,697,999, TO DR. PAUL KEIM TO CREATE TESTS THAT WOULD RAPIDLY CHARACTERIZE AND IDENTIFY THE NATURAL OR MAN-MADE SOURCES OF DISEASE OUTBREAKS. 12. 2-YEAR NIH GRANT, TOTALING $1,436,000, TO DR. DAVID CRAIG FOR DATA PROCESSING AND VISUALIZATION IN CONJUNCTION WITH THE INTERNATIONAL 1000 GENOMES PROJECT, WHICH WOULD CATALOGUE COMMON HUMAN GENETIC VARIABILITY. 13. TWO, 2-YEAR NIH GRANTS, TOTALING $1,093,274 AND $225, 044, TO DR. DAVID DUGGAN FOR ADVANCING THE STUDY OF THE EPIDEMIOLOGY OF PUTATIVE GENUINE GENETIC VARIANTS. ENTERPRISE EFFORTS AND COLLABORATION TGEN'S OFFICES OF BUSINESS DEVELOPMENT AND TECHNOLOGY TRANSFER WORK TO DEVELOP AN APPROPRIATE ADMINISTRATIVE STRUCTURE TO HANDLE COMMERCIALIZATION OF ITS INTELLECTUAL PROPERTY, AS WELL AS TO DEVELOP EFFECTIVE WAYS TO PARTNER WITH THE COMMERCIAL SECTOR. THE TECHNOLOGY TRANSFER OFFICE (TTO) FACILITATES AND ACCELERATES THE COMMERCIALIZATION OF TGEN'S SCIENTIFIC DISCOVERIES FOR THE BENEFIT OF HUMAN HEALTH BY: - IDENTIFYING, PATENTING AND LICENSING NEW TECHNOLOGY; - FACILITATING ACCESS AND EXCHANGE OF RESEARCH MATERIALS, TECHNOLOGIES, AND DATA VIA MATERIAL TRANSFER AGREEMENTS (MTAS) OR CONFIDENTIAL DISCLOSURE AGREEMENTS (CDAS); - NEGOTIATING COLLABORATIVE RESEARCH AGREEMENTS; AND - ASSISTING IN THE FORMATION OF START-UP COMPANIES WHEN APPROPRIATE. INVENTION DISCLOSURES TGEN SCIENTISTS WORK WITH THE OFFICE OF TECHNOLOGY TRANSFER (OTT) TO FILE INVENTION DISCLOSURES AS THE FIRST STEP TOWARD A POSSIBLE PATENT APPLICATION OR OTHER APPROPRIATE FORM OF INTELLECTUAL PROPERTY PROTECTION. TGEN FILED 26 INVENTION DISCLOSURES IN FY10 BASED ON DISCOVERIES STEMMING FROM TGEN-LED RESEARCH AND FILED 21 PROVISIONAL PATENT APPLICATIONS. COMMERCIALIZATION / SPIN OFFS IN TERMS OF COMMERCIALIZATION AND COMPANY FORMATION, TGEN SIGNED 3 LICENSE AGREEMENTS IN FY10. | |
| CONTRACTS AND COLLABORATIONS | TGEN SIGNED A TOTAL OF 386 CONTRACTS IN FY10, BROKEN DOWN AS FOLLOWS: 1. TGEN SIGNED 87 CONFIDENTIAL DISCLOSURE AGREEMENTS (CDA) IN FY10. 2. TGEN SIGNED 102 MATERIAL TRANSFER AGREEMENTS (MTA) IN FY10. 3. TGEN SIGNED 85 RESEARCH COLLABORATIONS (ANY WITH LOCAL AND STATE AFFILIATIONS) IN FY10, INCLUDING AGREEMENTS THAT FURTHER RESEARCH INTO A HOST OF DISEASES, INCLUDING BRAIN CANCER, MELANOMA, ALZHEIMER'S AND AUTISM. 4. ADDITIONALLY, TGEN SIGNED 18 CONSULTING AGREEMENTS, 69 PROFESSIONAL SERVICES AGREEMENTS, 9 COMMERCIALIZATION LICENSES, AND 16 AGREEMENTS COVERING MISCELLANEOUS ACTIVITIES. JOB CREATION 36 NEW FULL-TIME EQUIVALENT POSITIONS WERE CREATED IN FY10 WITH SALARIES AND BENEFITS TOTALING APPROXIMATELY $2,550,475. SALARIES FOR TEMPORARY POSITIONS (THOSE POSITIONS CREATED FOR A FINITE PERIOD OF TIME) TOTALED $160,000 AND STUDENT SALARIES WERE JUST OVER $390,000, BRINGING THE OVERALL TOTAL TO $3,100.475. TGEN STAFF NOW TOTAL 284, OF WHICH 83 PERCENT HOLD A COLLEGE DEGREE (48 PERCENT HOLD AN ADVANCED DEGREE). FY10 POSITIONS FILLED INCLUDE: ADMINISTRATIVE ASSISTANT ASSOCIATE INVESTIGATOR DEVELOPMENT ASSOCIATE BIOINFORMATICIAN BIOINFORMATICIAN II CLINICAL INFORMATICS PROGRAMMER CLINICAL TRANSLATIONAL RESEARCH DIVISION, DEPUTY DIRECTOR DESKTOP SUPPORT SPECIALIST GRANT PROGRAM MANAGER OPERATIONS MANAGER POST-DOCTORAL FELLOW RESEARCH ASSOCIATE RESEARCH ASSOCIATE II SOFTWARE ENGINEER SOFTWARE QA ENGINEER SENIOR INVESTIGATOR SENIOR STAFF SCIENTIST STAFF SCIENTIST WE HAVE STRESSED IN THE PAST THAT INTERNSHIPS SERVE AS A PIPELINE TO TGEN IN TERMS OF FUTURE RECRUITMENT AND SUPPORT THE STATEWIDE INITIATIVE TOWARDS EDUCATION AND DEVELOPMENT FOR THE STUDENTS IN THE LIFE SCIENCES. ADDITIONALLY, TGEN IS A PROVING GROUND WHERE TALENTED UNDERGRADUATES GAIN VALUABLE EXPERIENCE PRIOR TO RETURNING TO EARN ADVANCED DEGREES AT ONE OF THE STATE'S THREE UNIVERSITIES. TGEN HIRED FOUR SUCH CANDIDATES IN FY10, WHILE 14 EMPLOYEES RETURNED TO UNIVERSITY TO FURTHER THEIR BIOMEDICAL EDUCATION. EDUCATION AND PUBLIC OUTREACH INTERNSHIPS 2010 SAW 44 BIOSCIENCE STUDENTS COMPLETING THE 2010 HELIOS SCHOLARS PROGRAM AT TGEN, AND 23 NON-HELIOS STUDENTS CONDUCTING INTERNSHIPS - SCIENTIFIC AND ADMINISTRATIVE - IN A NUMBER OF TGEN LABS AND DEPARTMENTS. SIXTEEN FEMALES AND 28 MALES COMPRISED THE HELIOS SCHOLARS, BROKEN DOWN AS FOLLOWS: 32 PERCENT HIGH SCHOOL, 57 PERCENT UNDERGRADUATE, AND 11 PERCENT GRADUATE/MEDICAL SCHOOL. SEVENTEEN FEMALES AND SIX MALES COMPRISED THE 23 NON HELIOS STUDENTS CONDUCTING INTERNSHIPS AT TGEN IN FY10, BROKEN DOWN AS FOLLOWS: 9 PERCENT HIGH SCHOOL, 70 PERCENT UNDERGRADUATE, AND 21 PERCENT GRADUATE/MEDICAL SCHOOL. NEW IN FY10 (FALL '09), TGEN AND THE PHOENIX BIOSCIENCE HIGH SCHOOL LAUNCHED A PILOT INTERNSHIP PROGRAM FOR THEIR SENIOR STUDENTS. THE STUDENTS RECEIVE CREDIT IN EXCHANGE FOR THE COMPLETION OF A MINIMUM NUMBER OF HOURS (120) IN A RESEARCH LAB ENVIRONMENT. TEACHER TRAINING PROGRAM IN FY10, TGEN COMPLETED ITS SECOND YEAR OF A 5-YEAR TRAINING AWARD IN COLLABORATION WITH NORTHERN ARIZONA UNIVERSITY TO CONDUCT A SUMMER GENOMICS WORKSHOP FOR TEACHERS AND GRADUATE STUDENTS AS PART OF AN NSF GRANT CALLED BIOTECHNOLOGY INTEGRATION OPPORTUNITIES FOR TEACHER EDUCATION AND CONTENT (BIOTEC). THIS GRANT PARTNERS THE COLLEGE OF ENGINEERING AND NATURAL SCIENCES, THE COLLEGE OF EDUCATION AT NORTHERN ARIZONA UNIVERSITY, AND TGEN IN ORDER TO ENHANCE INQUIRY-BASED SCIENCE TEACHING IN GRADES 5, 7, AND 9 WHILE EXPANDING THE INTERDISCIPLINARY PREPARATION OF GRADUATE STUDENTS IN BIOTECHNOLOGY. EDUCATIONAL AND PUBLIC TOURS IN FY10, TGEN HOSTED 46 PUBLIC TOURS FOR A DIVERSE RANGE OF COMMUNITY MEMBERS AND ORGANIZATIONS (TOTALING NEARLY 1,000 IN NUMBER), AS WELL AS SENT REPRESENTATIVES INTO THE COMMUNITY TO PRESENT AT FUNCTIONS, CAREER AND EDUCATIONAL FAIRS. STIMULATING GROWTH OF ARIZONA'S LIFE SCIENCE INDUSTRIES AN IMPORTANT FACTOR IN CONTINUING TGEN'S SUCCESS IS COMMUNICATION WITH VARIOUS STAKEHOLDERS AND THE BROADER ARIZONA COMMUNITY. TOWARD THAT GOAL, TGEN SR. LEADERSHIP PARTICIPATES IN A MYRIAD OF COMMUNITY-RELATED ACTIVITIES THROUGH PRESENTATIONS AT REGIONAL MEETINGS AND AS A MEMBER OR PARTICIPANT OF VARIOUS COMMITTEES AND GROUPS, INCLUDING THE ARIZONA ALZHEIMER'S CONSORTIUM BOARD, ARIZONA BIOSCIENCE ROADMAP STEERING COMMITTEE AND ARIZONA BIOSCIENCE ROADMAP EDUCATION & WORKFORCE DEVELOPMENT COMMITTEE, ARIZONA SKILL STANDARDS COMMISSION, ARIZONA TECHNOLOGY COUNCIL, GREATER PHOENIX LEADERSHIP, NSF STEP GRANT ADVISORY BOARD- FOR ESTRELLA MOUNTAIN CC AND MORE. | |
| MEDIA | TGEN REMAINS ACTIVE IN PURSUING POSITIVE EARNED MEDIA EXPOSURE FOR THE INSTITUTE'S RESEARCH AND PHILANTHROPIC ACTIVITIES. MEDIA EXPOSURE RAISES AWARENESS AND BRINGS ADDED CREDIBILITY TO THE INSTITUTE AND THE STATE. IN TOTAL, TGEN RECEIVED GREATER THAN 1300 MEDIA MENTIONS IN FY10 IN VARIOUS TRADE AND PUBLIC MEDIA: LOCALLY, NATIONALLY AND INTERNATIONALLY. WHILE CITING TGEN SPECIFICALLY, THESE ARTICLES AND NEWS BRIEFS HELP BUILD A GREATER PRESENCE FOR THE CONTINUOUSLY EXPANDING BIOMEDICAL SCIENCE INITIATIVES OCCURRING IN ARIZONA. MEDIA OUTLETS INCLUDE: FOX10 NEWSMAKER SUNDAY BUSINESS WIRE STATES NEWS SERVICE THE ARIZONA REPUBLIC PHOENIX BUSINESS JOURNAL ARIZONA BUSINESS GAZETTE ARIZONA DAILY STAR JEWISH NEWS OF GREATER PHOENIX GRAND RAPIDS PRESS THE STAR-LEDGER (NEWARK, N.J.) PLAIN DEALER (CLEVELAND) ASIAN NEWS INTERNATIONAL (ANI) BIOTECH WEEK PR NEWSWIRE MARKETWIRE THE HILL LIFE SCIENCE WEEKLY HEALTH & MEDICINE WEEK GENOMEWEB ON-LINE TGEN'S ON-LINE PRESENCE CONTINUES TO INCREASE ON AN ANNUAL BASIS. WITH TWO ACTIVE SITES (TGEN AND THE TGEN FOUNDATION) MORE THAN 1.2 MILLION PAGE VIEWS WERE RECORDED IN FY10. THE WEB SERVES AS A PORTAL TO ALLOW ARIZONANS - AND OTHERS WORLDWIDE- TO LEARN ABOUT THE RESEARCH AND DISCOVERIES COMING OUT OF TGEN LABS. ADDITIONALLY, THE TGEN FOUNDATION WEB PAGES ALLOW SUPPORTERS TO CREATE MEMORIALS AND FUNDRAISING PAGES IN SUPPORT OF TGEN'S EFFORTS TO DEVELOP IMPROVED DIAGNOSTIC TOOLS AND NEW THERAPEUTICS THAT TARGET A HOST OF DISEASES. TGEN'S RECENTLY LAUNCHED SOCIAL MEDIA (FACEBOOK, TWITTER) PROVIDES A FURTHER OPPORTUNITY TO COMMUNICATE WITH NUMEROUS CONSTITUENCIES THROUGH EVER-INCREASING MEDIUMS. | |
| FORM 990, PART VI, LINE 6 | DESCRIPTION OF SIGNIFICANT CHANGES TO BYLAWS | FORM 990, PART VI, LINE 6 CLASSES OF MEMBERS AND THE NATURE OF THEIR RIGHTS LINE 6 - THE SOLE CORPORATE MEMBER OF THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE FOUNDATION (TGEN FOUNDATION) IS THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN). |
| FORM 990, PART VI, LINES 7A & 7B | DECISIONS REQUIRING APPROVAL | LINE 7A - TGEN, AS THE SOLE CORPORATE MEMBER OF TGEN FOUNDATION, HAS THE RIGHT TO ELECT THE BOARD OF DIRECTORS OF TGEN FOUNDATION. LINE 7B - THE SOLE CORPORATE MEMBER'S VOTE SHALL BE REQUIRED ON: A) THE ELECTION AND REMOVAL OF ELECTED DIRECTORS AS SET FORTH IN THE BYLAWS; B) THE ADOPTION OF ANY PLAN OF MERGER OR CONSOLIDATION; C) THE SALE OF ALL OR SUBSTANTIALLY ALL THE FOUNDATION'S ASSETS IN A SINGLE TRANSACTION OR SERIES OF RELATED TRANSACTIONS; D) THE AMENDMENT OF THE FOUNDATION'S ARTICLES OF INCORPORATION OR BYLAWS; E) THE INSTITUTION, OR CONSENT TO INSTITUTION, OF PROCEEDINGS TO ADJUDICATE THE FOUNDATION BANKRUPT OR INSOLVENT, OR THE FILING OF A PETITION SEEKING OR CONSENTING TO REORGANIZATION OR RELIEF UNDER ANY LAW RELATING TO BANKRUPTCY, INSOLVENCY, OR OTHER RELIEF FOR DEBTORS, OR THE CONSENT TO THE APPOINTMENT OF A RECEIVER, LIQUIDATOR, ASSIGNEE, TRUSTEE, SEQUESTRATOR (OR SIMILAR OFFICIAL) OF THE FOUNDATION OR OF ALL OR ANY SUBSTANTIAL PART OF ITS PROPERTY, OR THE MAKING OF ANY ASSIGNMENT FOR THE BENEFIT OF CREDITORS, OR THE ADMISSION IN WRITING OF THE FOUNDATION'S INABILITY TO PAY ITS DEBTS GENERALLY AS THEY BECOME DUE, OR ANY STEPS IN FURTHERANCE OF SUCH ACTION; AND F) THOSE MATTERS UPON WHICH THE MEMBER IS GRANTED VOTING RIGHTS IN THE ARTICLES OF INCORPORATION, BYLAWS, OR THE ARIZONA NONPROFIT CORPORATION ACT. THE SOLE CORPORATE MEMBER HAS THE FOLLOWING RESERVE POWERS: A) APPOINT AND REMOVE THE PRESIDENT; B) APPROVE THE ESTABLISHMENT OF NEW CORPORATE PARTNERSHIP ENTITIES CREATED OR JOINED BY THE FOUNDATION; C) APPROVE THE FOUNDATION'S EXECUTION OF MATERIAL CONTRACTS; AND D) APPROVE THE FOUNDATION'S INCURRENCE OF MATERIAL DEBTS. |
| FORM 990, PART VI, LINE 11 | PROCESS USED BY MANAGEMENT AND/OR GOVERNING BODY TO REVIEW FORM 990 | THE FORM 990 IS PREPARED BY AN OUTSIDE ACCOUNTING FIRM BASED ON INFORMATION PROVIDED BY THE FINANCE DEPARTMENT. THE 990 IS THEN REVIEWED BY MANAGEMENT IN THE FINANCE DEPARTMENT AND POSTED ON THE BOARD WEBSITE. |
| FORM 990, PART VI, LINE 12C | PROCESS USED TO MONITOR TRANSACTIONS FOR CONFLICTS OF INTEREST | TGEN Foundation issues a conflict of interest questionnaire on an annual basis to all Foundation Director level positions and above in addition to any key employees designated by the Foundation President and/or Chief Operating Officer. The questionnaires are reviewed by the Chief Financial Officer and those employees with conflicts are sent for further review to the Foundation President and/or Chief Operating Officer to ensure a plan is set forth. Updates to the list are handled on an as needed basis based on contract reviews and employee information. |
| FORM 990, PART VI, LINES 15A AND 15B | PROCESS USED TO DETERMINE COMPENSATION | TGen Foundation does not have any direct employees. Compensation is determined by The Translational Genomics Research Institute (Tgen) using the following process: TGen's Governance and Executive Compensation Committee will act in an "advice and consent" capacity reviewing the recommendations for the President and Scientific Director regarding the compensation of disqualified persons and forwarding final recommendations to the full Board for approval. Disqualified persons (except for the President and Scientific Director) will not be present for, or participate in, Committee deliberations concerning their compensation (other than to answer questions). The President and Scientific Director will participate in the deliberations concerning the compensation of direct reports. During the decision-making process, the Committee will adhere to the Executive Compensation philosophy. The Committee is authorized (and provided with sufficient funding) to annually engage outside independent compensation and legal advisors when deemed necessary and advisable. The Committee will comply with the "Rebuttable Presumption of Reasonableness" under Section 4958 of the Internal Revenue Code whenever possible. The Committee will review and understand the Internal Revenue Code provisions dealing with "excess benefit transactions concerning Disqualified Persons' compensation". When developing a compensation philosophy, TGen kept in mind the following factors: The TGen mission and strategy The TGen culture Trends in compensation in the external environment Trends in recruitment of new employees Trends in organizational employee turnover TGen's life cycle stage |
| FORM 990, PART VI, LINE 19 | AVAILABILITY OF GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY, AND | FINANCIAL STATEMENTS TO THE GENERAL PUBLIC TGEN FOUNDATION PROVIDES ITS GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY AND FINANCIAL STATEMENTS TO THE GENERAL PUBLIC UPON REQUEST. |
| FORM 990, PART VII | HOURS DEVOTED TO RELATED ORGANIZATIONS | THE ORGANIZATION DOES NOT DIRECTLY HAVE ANY EMPLOYEES. THE FOLLOWING INDIVIDUALS REPORTED IN PART VII ARE PAID BY THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN), A RELATED TAX-EXEMPT ORGANIZATION, FOR SERVICES PROVIDED TO TGEN FOUNDATION: MICHAEL BASSOFF DENISE MCCLINTIC THESE INDIVIDUALS DEVOTE 40 HOURS PER WEEK TO TGEN FOUNDATION AND NO HOURS PER WEEK TO TGEN. THE FOLLOWING INDIVIDUALS REPORTED IN PART VII ARE PAID BY THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN), A RELATED TAX-EXEMPT ORGANIZATION, FOR SERVICES PROVIDED TO TGEN: JEFFREY TRENT TERESA BURLESON THEY DEVOTE 40 HOURS PER WEEK TO TGEN AND 1 HOUR PER WEEK TO TGEN FOUNDATION. |
Schedule R IRS990ScheduleR
Form990 Schedule R Part II Form990ScheduleRPartII (2 entries)
| Address Line1AddressUS/AddressLine1 | CityAddressUS/City | StateAddressUS/State | ZIP CodeAddressUS/ZIPCode | EINEIN | Primary ActivitiesPrimaryActivities | Legal Domicile StateLegalDomicileState | Exempt Code SectionExemptCodeSection | Public Charity StatusPublicCharityStatus | Business Name Line1DirectControllingEntityName/BusinessNameLine1 |
|---|---|---|---|---|---|---|---|---|---|
| THE TRANSLATIONAL GENOMICS RESEARCH INST | |||||||||
| 445 NORTH 5TH STREET | PHOENIX | AZ | 85004 | 753065445 | RESEARCH | AZ | 501(C)(3) | 7 | VARI |
| VAN ANDEL RESEARCH INSTITUTE | |||||||||
| 333 BOSTWICK AVE STE 850 | GRAND RAPIDS | MI | 49503 | 522000823 | MEDICAL RSCH | MI | 501(C)(3) | 4 | NA |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Receipt Of Int Ann Rents Royalties | false | ReceiptOfIntAnnRentsRoyalties |
| Gift Grant Or Cap Contr To Other Org | true | GiftGrantOrCapContrToOtherOrg |
| Gift Grant Or Cap Contr Fr Other Org | false | GiftGrantOrCapContrFrOtherOrg |
| Loans Or Guarantees To Other Org | false | LoansOrGuaranteesToOtherOrg |
| Loans Or Guarantees From Other Org | false | LoansOrGuaranteesFromOtherOrg |
| Sale Of Assets To Other Org | false | SaleOfAssetsToOtherOrg |
| Purchase Of Assets From Other Org | false | PurchaseOfAssetsFromOtherOrg |
| Exchange Of Assets | false | ExchangeOfAssets |
| Rental Of Facilities To Other Orgs | false | RentalOfFacilitiesToOtherOrgs |
| Rental Of Facilities Fr Other Orgs | false | RentalOfFacilitiesFrOtherOrgs |
| Perform Of Services For Other Orgs | true | PerformOfServicesForOtherOrgs |
| Perform Of Services By Other Orgs | false | PerformOfServicesByOtherOrgs |
| Sharing Of Facilities | false | SharingOfFacilities |
| Sharing Of Paid Employees | false | SharingOfPaidEmployees |
| Reimbursement Paid To Other Org | false | ReimbursementPaidToOtherOrg |
| Reimbursement Paid By Other Org | true | ReimbursementPaidByOtherOrg |
| Other Transfer To Other Org | false | OtherTransferToOtherOrg |
| Other Transfer From Other Org | false | OtherTransferFromOtherOrg |
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