VAN ANDEL RESEARCH INSTITUTE: Form 990, tax year 2010
View the entire original 990 at ProPublica ↗
- Organization
- VAN ANDEL RESEARCH INSTITUTE (EIN 52-2000823)
- Tax period
- 2010-12-01 to 2011-11-30
- Filed
- 2012-10-12
- IRS object ID
- 201202869349300330
- Schema version
- 2010v3.4
- Source
- Download XML · Original 990 at ProPublica
Every field in the e-filed return. Faint text is the IRS element name, for citing.
- Return header
- Form 990
- Schedule A
- Schedule B
- Schedule C
- Schedule D
- Schedule F
- Schedule I
- Schedule J
- Schedule K
- Schedule O
- Schedule R
Return header ReturnHeader
| Field | Value | IRS element (for citing) |
|---|---|---|
| Timestamp | 2012-10-12T13:21:17-05:00 | Timestamp |
| Tax Period End Date | 2011-11-30 | TaxPeriodEndDate |
Preparer Firm PreparerFirm
Preparer Firm Business Name PreparerFirmBusinessName
| Field | Value | IRS element (for citing) |
|---|---|---|
| Business Name Line1 | DELOITTE TAX LLP | BusinessNameLine1 |
Preparer Firm US Address PreparerFirmUSAddress
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | 200 RENAISSANCE CENTER STE 3900 | AddressLine1 |
| City | DETROIT | City |
| State | MI | State |
| ZIP Code | 48243 | ZIPCode |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Return Type | 990 | ReturnType |
| Tax Period Begin Date | 2010-12-01 | TaxPeriodBeginDate |
Filer Filer
| Field | Value | IRS element (for citing) |
|---|---|---|
| EIN | 522000823 | EIN |
Name Name
| Field | Value | IRS element (for citing) |
|---|---|---|
| Business Name Line1 | VAN ANDEL RESEARCH INSTITUTE | BusinessNameLine1 |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Name Control | VANA | NameControl |
| Phone | 6162345000 | Phone |
US Address USAddress
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | 333 BOSTWICK AVENUE NE | AddressLine1 |
| City | GRAND RAPIDS | City |
| State | MI | State |
| ZIP Code | 49503 | ZIPCode |
Officer Officer
| Field | Value | IRS element (for citing) |
|---|---|---|
| Name | TIMOTHY J MYERS | Name |
| Title | CFO | Title |
| Phone | 6162345368 | Phone |
| Date Signed | 2012-10-12 | DateSigned |
| Authorize Third Party | 1 | AuthorizeThirdParty |
Preparer Preparer
| Field | Value | IRS element (for citing) |
|---|---|---|
| Name | LORI BOYCE | Name |
| Phone | 3133963000 | Phone |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Tax Year | 2010 | TaxYear |
| Build TS | 2016-02-24 21:20:13Z | BuildTS |
Form 990 IRS990
| Field | Value | IRS element (for citing) |
|---|---|---|
| Name Of Principal Officer Person | TIMOTHY J MYERS | NameOfPrincipalOfficerPerson |
Address Principal Officer US AddressPrincipalOfficerUS
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | 333 BOSTWICK AVENUE NE | AddressLine1 |
| City | GRAND RAPIDS | City |
| State | MI | State |
| ZIP Code | 49503 | ZIPCode |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Gross Receipts | 64949975 | GrossReceipts |
| Group Return For Affiliates | 0 | GroupReturnForAffiliates |
| Organization501c3 | X | Organization501c3 |
| Web Site | WWW.VAI.ORG | WebSite |
| Type Of Organization Trust | X | TypeOfOrganizationTrust |
| Year Formation | 1996 | YearFormation |
| State Legal Domicile | MI | StateLegalDomicile |
| Activity Or Mission Description | MEDICAL RESEARCH ORGANIZATION | ActivityOrMissionDescription |
| Nbr Voting Members Governing Body | 7 | NbrVotingMembersGoverningBody |
| Nbr Independent Voting Members | 4 | NbrIndependentVotingMembers |
| Total Nbr Employees | 345 | TotalNbrEmployees |
| Total Nbr Volunteers | 0 | TotalNbrVolunteers |
| Total Gross UBI | 1293324 | TotalGrossUBI |
| Net Unrelated Business Txbl Income | 319272 | NetUnrelatedBusinessTxblIncome |
| Contributions Grants Prior Year | 69868505 | ContributionsGrantsPriorYear |
| Contributions Grants Current Year | 57012820 | ContributionsGrantsCurrentYear |
| Program Service Revenue Prior Year | 1332729 | ProgramServiceRevenuePriorYear |
| Program Service Revenue CY | 1522584 | ProgramServiceRevenueCY |
| Investment Income Prior Year | -272304 | InvestmentIncomePriorYear |
| Investment Income Current Year | 819423 | InvestmentIncomeCurrentYear |
| Other Revenue Prior Year | 5766282 | OtherRevenuePriorYear |
| Other Revenue Current Year | 4334013 | OtherRevenueCurrentYear |
| Total Revenue Prior Year | 76695212 | TotalRevenuePriorYear |
| Total Revenue Current Year | 63688840 | TotalRevenueCurrentYear |
| Grants And Similar Amnts Prior Year | 221029 | GrantsAndSimilarAmntsPriorYear |
| Grants And Similar Amnts CY | 340825 | GrantsAndSimilarAmntsCY |
| Benefits Paid To Members Prior Year | 0 | BenefitsPaidToMembersPriorYear |
| Benefits Paid To Members CY | 0 | BenefitsPaidToMembersCY |
| Salaries Etc Prior Year | 22508665 | SalariesEtcPriorYear |
| Salaries Etc Current Year | 26065382 | SalariesEtcCurrentYear |
| Total Prof Fundrsng Exp Prior Year | 0 | TotalProfFundrsngExpPriorYear |
| Total Prof Fundrsng Exp CY | 0 | TotalProfFundrsngExpCY |
| Total Fundrsng Exp Current Year | 465513 | TotalFundrsngExpCurrentYear |
| Other Expense Prior Year | 69776826 | OtherExpensePriorYear |
| Other Expenses Current Year | 39147197 | OtherExpensesCurrentYear |
| Total Expenses Prior Year | 92506520 | TotalExpensesPriorYear |
| Total Expenses Current Year | 65553404 | TotalExpensesCurrentYear |
| Revenues Less Expenses Prior Year | -15811308 | RevenuesLessExpensesPriorYear |
| Revenues Less Expenses CY | -1864564 | RevenuesLessExpensesCY |
| Total Assets BOY | 253776425 | TotalAssetsBOY |
| Total Assets EOY | 270167888 | TotalAssetsEOY |
| Total Liabilities BOY | 312690617 | TotalLiabilitiesBOY |
| Total Liabilities EOY | 358085475 | TotalLiabilitiesEOY |
| Net Assets Or Fund Balances BOY | -58914192 | NetAssetsOrFundBalancesBOY |
| Net Assets Or Fund Balances EOY | -87917587 | NetAssetsOrFundBalancesEOY |
| Mission Description | MEDICAL RESEARCH ORGANIZATION | MissionDescription |
| Significant New Program Services | 0 | SignificantNewProgramServices |
| Significant Change | 0 | SignificantChange |
| Expense | 2294558 | Expense |
| Description | THE LABORATORY OF STRUCTURAL SCIENCES IS FOCUSED ON STUDYING THE STRUCTURES AND FUNCTIONS OF PROTEIN/ LIGAND COMPLEXES THAT PLAY KEY ROLES IN MAJOR HORMONE SIGNALING PATHWAYS. SEE SCHEDULE O FOR FURTHER INFORMATION ABOUT THIS PROGRAM. | Description |
Activity2 Activity2
| Field | Value | IRS element (for citing) |
|---|---|---|
| Expense | 1913728 | Expense |
| Description | THE LABORATORY OF MOLECULAR ONCOLOGY HAS FOCUSED ON UNDERSTANDING THE NUMEROUS AND DIVERSE ROLES THAT MET PLAYS IN MALIGNANT PROGRESSION AND METASTASIS. SCHEDULE O PROVIDES FURTHER INFORMATION REGARDING THIS PROGRAM'S ACCOMPLISHMENTS. | Description |
Activity3 Activity3
| Field | Value | IRS element (for citing) |
|---|---|---|
| Expense | 1374533 | Expense |
| Revenue | 1137649 | Revenue |
| Description | THE LABORATORY FOR TRANSLATIONAL MEDICINE IS FOCUSED ON THE DEVELOPMENT AND UTILIZATION OF MOLECULAR AND COMPUTATIONAL TECHNOLOGIES TO STUDY HOW A TUMOR SPREADS TO DISTANT PARTS OF THE BODY FROM ITS ORIGINAL LOCATION (METASTASIS), AND IDENTIFYING APPROACHES TO TREAT SUCH AGGRESSIVE CANCERS USING A "PERSONALIZED MEDICINE" APPROACH. SEE SCHEDULE O FOR FURTHER INFORMATION ABOUT THIS PROGRAM. | Description |
Activity Other ActivityOther
| Field | Value | IRS element (for citing) |
|---|---|---|
| Expense | 38027999 | Expense |
| Grants | 490825 | Grants |
| Revenue | 2080528 | Revenue |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Of Other Program Service Exp | 38027999 | TotalOfOtherProgramServiceExp |
| Total Of Other Program Service Grnt | 490825 | TotalOfOtherProgramServiceGrnt |
| Total Of Other Program Service Rev | 2080528 | TotalOfOtherProgramServiceRev |
| Total Program Service Expense | 43610818 | TotalProgramServiceExpense |
| Described In501 C3 | 1 | DescribedIn501C3 |
| Schedule B Required | 1 | ScheduleBRequired |
| Political Activities | 0 | PoliticalActivities |
| Lobbying Activities | 1 | LobbyingActivities |
| Donor Advised Funds | 0 | DonorAdvisedFunds |
| Conservation Easements | 0 | ConservationEasements |
| Collections Of Art | 1 | CollectionsOfArt |
| Credit Counseling | 0 | CreditCounseling |
| Term Or Permanent Endowments | 0 | TermOrPermanentEndowments |
| Report Land Bldg Equip | 1 | ReportLandBldgEquip |
| Report Invest Oth Securities | 0 | ReportInvestOthSecurities |
| Report Prog Rel Invest | 0 | ReportProgRelInvest |
| Report Other Assets | 1 | ReportOtherAssets |
| Report Other Liabilities | 1 | ReportOtherLiabilities |
| Report Fin48 Footnote | 0 | ReportFin48Footnote |
| Independent Audit Financial Stmt | 0 | IndependentAuditFinancialStmt |
| Consolidated Audit Financial Stmt | 1 | ConsolidatedAuditFinancialStmt |
| School | 0 | School |
| Foreign Office | 1 | ForeignOffice |
| Foreign Activities | 1 | ForeignActivities |
| More Than5000 K To Organizations | 0 | MoreThan5000KToOrganizations |
| More Than5000 K To Individuals | 0 | MoreThan5000KToIndividuals |
| Professional Fundraising | 0 | ProfessionalFundraising |
| Fundraising Activities | 0 | FundraisingActivities |
| Gaming | 0 | Gaming |
| Hospital | 0 | Hospital |
| Grants To Organizations | 0 | GrantsToOrganizations |
| Grants To Individuals | 1 | GrantsToIndividuals |
| Schedule J Required | 1 | ScheduleJRequired |
| Tax Exempt Bonds | 1 | TaxExemptBonds |
| Invest Tax Exempt Bonds | 0 | InvestTaxExemptBonds |
| Escrow Account | 0 | EscrowAccount |
| On Behalf Of Issuer | 0 | OnBehalfOfIssuer |
| Excess Benefit Transaction | 0 | ExcessBenefitTransaction |
| Prior Excess Benefit Transaction | 0 | PriorExcessBenefitTransaction |
| Loan To Officer Or DQP | 0 | LoanToOfficerOrDQP |
| Grant To Related Person | 0 | GrantToRelatedPerson |
| Bsnss Rltnshp With Organization | 0 | BsnssRltnshpWithOrganization |
| Bsnss Rltnshp Thru Family Member | 0 | BsnssRltnshpThruFamilyMember |
| Officer Entity With Bsnss Rltnshp | 0 | OfficerEntityWithBsnssRltnshp |
| Deductible Non Cash Contributions | 0 | DeductibleNonCashContributions |
| Deductible Contributions Of Art | 0 | DeductibleContributionsOfArt |
| Terminated | 0 | Terminated |
| Partial Liquidation | 0 | PartialLiquidation |
| Disregarded Entity | 1 | DisregardedEntity |
| Related Entity | 1 | RelatedEntity |
| Related Org Controlled Entity | 1 | RelatedOrgControlledEntity |
| Transaction Related Entity | 1 | TransactionRelatedEntity |
| Transfers To Exempt Non Chrtbl Org | 0 | TransfersToExemptNonChrtblOrg |
| Activities Conducted Partnership | 0 | ActivitiesConductedPartnership |
| Schedule O Required | 1 | ScheduleORequired |
| Number Forms Transmitted With1096 | 91 | NumberFormsTransmittedWith1096 |
| Number W2 G Included | 0 | NumberW2GIncluded |
| Number Of Employees | 345 | NumberOfEmployees |
| Employment Tax Returns Filed | 1 | EmploymentTaxReturnsFiled |
| Unrelated Business Income | 1 | UnrelatedBusinessIncome |
| Form990-T Filed | 1 | Form990-TFiled |
| Foreign Financial Account | 0 | ForeignFinancialAccount |
| Prohibited Tax Shelter Trans | 0 | ProhibitedTaxShelterTrans |
| Taxable Party Notification | 0 | TaxablePartyNotification |
| Non Deductible Contributions | 0 | NonDeductibleContributions |
| Quid Pro Quo Contributions | 0 | QuidProQuoContributions |
| Form8282 Property Disposed Of | 0 | Form8282PropertyDisposedOf |
| Funds To Pay Premiums | 0 | FundsToPayPremiums |
| Premiums Paid | 0 | PremiumsPaid |
| Indoor Tanning Services | 0 | IndoorTanningServices |
| Info In Schedule O Part VI | X | InfoInScheduleOPartVI |
| Nbr Voting Governing Body Members | 7 | NbrVotingGoverningBodyMembers |
| Number Independent Voting Members | 4 | NumberIndependentVotingMembers |
| Family Or Business Relationship | 1 | FamilyOrBusinessRelationship |
| Delegation Of Management Duties | 1 | DelegationOfManagementDuties |
| Changes To Organizing Docs | 0 | ChangesToOrganizingDocs |
| Material Diversion Or Misuse | 0 | MaterialDiversionOrMisuse |
| Members Or Stockholders | 0 | MembersOrStockholders |
| Election Of Board Members | 1 | ElectionOfBoardMembers |
| Decisions Subject To Approval | 0 | DecisionsSubjectToApproval |
| Minutes Of Governing Body | 1 | MinutesOfGoverningBody |
| Minutes Of Committees | 1 | MinutesOfCommittees |
| Officer Mailing Address | 0 | OfficerMailingAddress |
| Local Chapters | 0 | LocalChapters |
| Form990 Provided To Governing Body | 1 | Form990ProvidedToGoverningBody |
| Conflict Of Interest Policy | 0 | ConflictOfInterestPolicy |
| Whistleblower Policy | 0 | WhistleblowerPolicy |
| Document Retention Policy | 0 | DocumentRetentionPolicy |
| Compensation Process CEO | 1 | CompensationProcessCEO |
| Compensation Process Other | 1 | CompensationProcessOther |
| Investment In Joint Venture | 1 | InvestmentInJointVenture |
| Written Policy Or Procedure | 0 | WrittenPolicyOrProcedure |
| States Where Copy Of Return Is Filed | MI | StatesWhereCopyOfReturnIsFiled |
| Upon Request | X | UponRequest |
The Books Are In Care Of TheBooksAreInCareOf
Name Business NameBusiness
| Field | Value | IRS element (for citing) |
|---|---|---|
| Business Name Line1 | TIMOTHY J MYERS CFO | BusinessNameLine1 |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Telephone Number | 6162345368 | TelephoneNumber |
Address US AddressUS
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | 333 BOSTWICK AVENUE NE | AddressLine1 |
| City | GRAND RAPIDS | City |
| State | MI | State |
| ZIP Code | 495032518 | ZIPCode |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Info In Schedule O Part VII | X | InfoInScheduleOPartVII |
Form990 Part VII Section A Form990PartVIISectionA (17 entries)
| TitleTitle | Average Hours Per WeekAverageHoursPerWeek | Individual Trustee Or DirectorIndividualTrusteeOrDirector | OfficerOfficer | Reportable Comp From OrganizationReportableCompFromOrganization | Reportable Comp From Related OrgsReportableCompFromRelatedOrgs | Other CompensationOtherCompensation | Highest Compensated EmployeeHighestCompensatedEmployee | FormerFormer |
|---|---|---|---|---|---|---|---|---|
| DAVID VAN ANDEL | ||||||||
| CHAIRMAN / CEO | 28.00 | X | X | 412250 | 0 | 129965 | ||
| GEORGE VANDE WOUDE | ||||||||
| TRUSTEE/ DIST INVESTIGATOR | 50.00 | X | 325763 | 0 | 44345 | |||
| DR JAMES FAHNER | ||||||||
| TRUSTEE | 1.00 | X | 10000 | 0 | 0 | |||
| DR FRITZ ROTTMAN PHD | ||||||||
| TRUSTEE | 1.00 | X | 10000 | 2000 | 0 | |||
| DR JEFFREY TRENT | ||||||||
| PRESIDENT & RESEARCH DIREC | 50.00 | X | X | 1043405 | 0 | 303030 | ||
| JOSE CARDENAS | ||||||||
| TRUSTEE | 1.00 | X | 10000 | 0 | 0 | |||
| WILLIAM POST | ||||||||
| TRUSTEE | 1.00 | X | 0 | 0 | 0 | |||
| R JACK FRICK | ||||||||
| CHIEF ADMINISTRATIVE OFFICER | 50.00 | X | 265597 | 0 | 101087 | |||
| TIMOTHY MYERS | ||||||||
| CHIEF FINANCIAL OFFICER | 50.00 | X | 156599 | 0 | 90958 | |||
| JEFFREY BATTERSHALL | ||||||||
| SECRETARY/ INTERIM CHIEF LEGAL | 1.00 | X | 0 | 0 | 0 | |||
| DAVID WHITESCARVER | ||||||||
| SECRETARY/ CHIEF LEGAL OFFICER | 50.00 | X | 0 | 0 | 0 | |||
| KATHLEEN VOGELSANG | ||||||||
| DIR OF INVESTMENTS | 45.00 | 180737 | 0 | 35576 | X | |||
| DR H ERIC XU | ||||||||
| DIST INVESTIGATOR | 45.00 | 267231 | 0 | 48773 | X | |||
| DR JAMES RESAU | ||||||||
| DIST INVESTIGATOR | 45.00 | 192433 | 0 | 39977 | X | |||
| JOHN BENDER | ||||||||
| CLINICAL OPERATIONS DIRECT | 45.00 | 233240 | 0 | 31603 | X | |||
| BRYON CAMPBELL | ||||||||
| CHIEF INFORMATION OFFICER | 45.00 | 179498 | 0 | 35557 | X | |||
| STEVE HEACOCK FORMER | ||||||||
| CAO / GENERAL COUNSEL | 8.00 | 615119 | 0 | 23095 | X | |||
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Reportable Comp From Org | 3901872 | TotalReportableCompFromOrg |
| Total Reportable Comp Frm Rltd Orgs | 2000 | TotalReportableCompFrmRltdOrgs |
| Total Other Compensation | 883966 | TotalOtherCompensation |
| Number Individuals GT100 K | 36 | NumberIndividualsGT100K |
| Formers Listed | 1 | FormersListed |
| Total Comp GT150 K | 1 | TotalCompGT150K |
| Compensation From Other Sources | 0 | CompensationFromOtherSources |
Contractor Compensation ContractorCompensation (5 entries)
| Address Line1AddressOfContractor/AddressUS/AddressLine1 | CityAddressOfContractor/AddressUS/City | StateAddressOfContractor/AddressUS/State | ZIP CodeAddressOfContractor/AddressUS/ZIPCode | Description Of ServicesDescriptionOfServices | CompensationCompensation |
|---|---|---|---|---|---|
| HUNT - OWEN AMES & KIMBALL (SEE SCHEDULE | |||||
| 6720 SCOTTSDALE DR STE 300 | SCOTTSDALE | AZ | 85253 | CONSTRUCTION SERVICES | 12393896 |
| BANK OF AMERICAMERRILL LYNCH | |||||
| 100 N TRYON ST | CHARLOTTE | NC | 28202 | CREDIT ENHANCEMENT FEES | 3600486 |
| AON RISK SERVICES CENTER INC | |||||
| 75 REMITTANCE DR STE 1943 | CHICAGO | IL | 606751943 | INSURANCE | 543679 |
| WARNER NORCROSS & JUDD | |||||
| 111 LYON ST 900 OLD KENT | GRAND RAPIDS | MI | 495032487 | LEGAL/ CONSULTING | 444669 |
| DK SECURITY INC | |||||
| 5160 FALCONVIEW AVE SE | KENTWOOD | MI | 49512 | SECURITY SERVICES | 420458 |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Number Of Contractors GT100 K | 24 | NumberOfContractorsGT100K |
| Related Organizations | 47313999 | RelatedOrganizations |
| Government Grants | 6982060 | GovernmentGrants |
| All Other Contributions | 2716761 | AllOtherContributions |
| Total Contributions | 57012820 | TotalContributions |
Program Service Revenue ProgramServiceRevenue
| Field | Value | IRS element (for citing) |
|---|---|---|
| Description | RESEARCH BILLED REV | Description |
| Business Code | 541700 | BusinessCode |
| Total Revenue Column | 1522584 | TotalRevenueColumn |
| Related Or Exempt Function Income | 235284 | RelatedOrExemptFunctionIncome |
| Unrelated Business Revenue | 1287300 | UnrelatedBusinessRevenue |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Program Service Revenue | 1522584 | TotalProgramServiceRevenue |
Investment Income InvestmentIncome
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 159959 | TotalRevenueColumn |
| Exclusion | $159,959 | ExclusionAmount |
Royalties Revenue RoyaltiesRevenue
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 242481 | TotalRevenueColumn |
| Exclusion | $242,481 | ExclusionAmount |
Gross Rents GrossRents
| Field | Value | IRS element (for citing) |
|---|---|---|
| Real | 2183955 | Real |
| Personal | 11679 | Personal |
Less Rental Expenses LessRentalExpenses
| Field | Value | IRS element (for citing) |
|---|---|---|
| Real | 1147826 | Real |
| Personal | 5655 | Personal |
Rental Income Or Loss RentalIncomeOrLoss
| Field | Value | IRS element (for citing) |
|---|---|---|
| Real | 1036129 | Real |
| Personal | 6024 | Personal |
Net Rental Income Or Loss NetRentalIncomeOrLoss
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 1042153 | TotalRevenueColumn |
| Related Or Exempt Function Income | 1036129 | RelatedOrExemptFunctionIncome |
| Unrelated Business Revenue | 6024 | UnrelatedBusinessRevenue |
Gross Amount Sales Assets GrossAmountSalesAssets
| Field | Value | IRS element (for citing) |
|---|---|---|
| Other | 767118 | Other |
Less Cost Oth Basis Sales Expenses LessCostOthBasisSalesExpenses
| Field | Value | IRS element (for citing) |
|---|---|---|
| Other | 107654 | Other |
Gain Or Loss GainOrLoss
| Field | Value | IRS element (for citing) |
|---|---|---|
| Other | 659464 | Other |
Net Gain Or Loss Investments NetGainOrLossInvestments
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 659464 | TotalRevenueColumn |
| Related Or Exempt Function Income | 659464 | RelatedOrExemptFunctionIncome |
Other Revenue Misc OtherRevenueMisc (3 entries)
| DescriptionDescription | Business CodeBusinessCode | Total Revenue ColumnTotalRevenueColumn | ExclusionExclusionAmount |
|---|---|---|---|
| REL. PARTY ADMIN SUPPO | 561000 | 4274282 | $4,274,282 |
| REIMBURSED EXPENSES | 900099 | 263846 | $263,846 |
| LOSS ON INVESTMENTS | 523000 | -1491927 | -$1,491,927 |
Miscellaneous Revenue MiscellaneousRevenue
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 3178 | TotalRevenueColumn |
| Exclusion | $3,178 | ExclusionAmount |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Other Revenue | 3049379 | TotalOtherRevenue |
Total Revenue TotalRevenue
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Revenue Column | 63688840 | TotalRevenueColumn |
| Related Or Exempt Function Income | 1930877 | RelatedOrExemptFunctionIncome |
| Unrelated Business Revenue | 1293324 | UnrelatedBusinessRevenue |
| Exclusion | $3,451,819 | ExclusionAmount |
Grants To Domestic Individuals GrantsToDomesticIndividuals
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 340825 | Total |
| Program Services | 340825 | ProgramServices |
Comp Current Officers Directors CompCurrentOfficersDirectors
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 2799911 | Total |
| Program Services | 1527558 | ProgramServices |
| Management And General | 1272353 | ManagementAndGeneral |
Other Salaries And Wages OtherSalariesAndWages
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 18030691 | Total |
| Program Services | 9952428 | ProgramServices |
| Management And General | 7662767 | ManagementAndGeneral |
| Fundraising | 415496 | Fundraising |
Pension Plan Contributions PensionPlanContributions
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 1517854 | Total |
| Program Services | 904745 | ProgramServices |
| Management And General | 587999 | ManagementAndGeneral |
| Fundraising | 25110 | Fundraising |
Other Employee Benefits OtherEmployeeBenefits
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 2388416 | Total |
| Program Services | 1423583 | ProgramServices |
| Management And General | 925003 | ManagementAndGeneral |
| Fundraising | 39830 | Fundraising |
Payroll Taxes PayrollTaxes
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 1328510 | Total |
| Program Services | 791961 | ProgramServices |
| Management And General | 514902 | ManagementAndGeneral |
| Fundraising | 21647 | Fundraising |
Fees For Services Legal FeesForServicesLegal
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 1133197 | Total |
| Program Services | 69871 | ProgramServices |
| Management And General | 1063326 | ManagementAndGeneral |
Fees For Services Accounting FeesForServicesAccounting
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 176968 | Total |
| Management And General | 176968 | ManagementAndGeneral |
Fees For Services Lobbying FeesForServicesLobbying
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 50000 | Total |
| Management And General | 50000 | ManagementAndGeneral |
Fees For Services Other FeesForServicesOther
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 2384795 | Total |
| Program Services | 1805653 | ProgramServices |
| Management And General | 579142 | ManagementAndGeneral |
Advertising Advertising
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 452400 | Total |
| Program Services | 36261 | ProgramServices |
| Management And General | 416139 | ManagementAndGeneral |
Office Expenses OfficeExpenses
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 141280 | Total |
| Program Services | 82483 | ProgramServices |
| Management And General | 58797 | ManagementAndGeneral |
Information Technology InformationTechnology
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 317986 | Total |
| Program Services | 134979 | ProgramServices |
| Management And General | 183007 | ManagementAndGeneral |
Occupancy Occupancy
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 2570936 | Total |
| Program Services | 1985561 | ProgramServices |
| Management And General | 585375 | ManagementAndGeneral |
Travel Travel
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 768754 | Total |
| Program Services | 551253 | ProgramServices |
| Management And General | 217501 | ManagementAndGeneral |
Conferences Meetings ConferencesMeetings
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 126927 | Total |
| Program Services | 94418 | ProgramServices |
| Management And General | 32509 | ManagementAndGeneral |
Interest Interest
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 11205203 | Total |
| Program Services | 8647481 | ProgramServices |
| Management And General | 2557722 | ManagementAndGeneral |
Depreciation Depletion DepreciationDepletion
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 10123630 | Total |
| Program Services | 8209616 | ProgramServices |
| Management And General | 1914014 | ManagementAndGeneral |
Insurance Insurance
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 370573 | Total |
| Program Services | 239644 | ProgramServices |
| Management And General | 130929 | ManagementAndGeneral |
Other Expenses OtherExpenses (5 entries)
| DescriptionDescription | TotalTotal | Program ServicesProgramServices | Management And GeneralManagementAndGeneral |
|---|---|---|---|
| LAB SUPPLIES & SERVICES | 3464855 | 3464855 | |
| EQUIPMENT & SOFTWARE | 1944232 | 1106860 | 837372 |
| OTHER SCIENTIFIC | 764424 | 764424 | |
| SCIENTIFIC PURCHASED SE | 705358 | 705358 | |
| RECRUITING AND RELOCATI | 586227 | 227871 | 358356 |
All Other Expenses AllOtherExpenses
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 1859452 | Total |
| Program Services | 543130 | ProgramServices |
| Management And General | 1352892 | ManagementAndGeneral |
| Fundraising | -36570 | Fundraising |
Total Functional Expenses TotalFunctionalExpenses
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total | 65553404 | Total |
| Program Services | 43610818 | ProgramServices |
| Management And General | 21477073 | ManagementAndGeneral |
| Fundraising | 465513 | Fundraising |
Savings And Temp Cash Investments SavingsAndTempCashInvestments
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 6671503 | BOY |
| EOY | 954773 | EOY |
Pledges And Grants Receivable PledgesAndGrantsReceivable
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 2623400 | BOY |
| EOY | 1194099 | EOY |
Accounts Receivable AccountsReceivable
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 1236706 | BOY |
| EOY | 2551038 | EOY |
Other Notes Loans Receivable Net OtherNotesLoansReceivableNet
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 2351000 | BOY |
| EOY | 1664455 | EOY |
Prepaid Expenses Deferred Charges PrepaidExpensesDeferredCharges
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 823236 | BOY |
| EOY | 1271897 | EOY |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Land Buildings Equipment Basis | 263656878 | LandBuildingsEquipmentBasis |
| Land Bldg Equipment Accum Deprec | 52776208 | LandBldgEquipmentAccumDeprec |
Land Buildings Equipment Basis Net LandBuildingsEquipmentBasisNet
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 219778822 | BOY |
| EOY | 210880670 | EOY |
Investments Other Securities InvestmentsOtherSecurities
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 1887951 | BOY |
| EOY | 1367061 | EOY |
Investments Program Related InvestmentsProgramRelated
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 97917 | BOY |
| EOY | 97917 | EOY |
Other Assets Total OtherAssetsTotal
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 18305890 | BOY |
| EOY | 50185978 | EOY |
Total Assets TotalAssets
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 253776425 | BOY |
| EOY | 270167888 | EOY |
Accounts Payable Accrued Expenses AccountsPayableAccruedExpenses
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 25465798 | BOY |
| EOY | 55926177 | EOY |
Deferred Revenue DeferredRevenue
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 1453448 | BOY |
| EOY | 1756331 | EOY |
Tax Exempt Bond Liabilities TaxExemptBondLiabilities
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 220000000 | BOY |
| EOY | 220385000 | EOY |
Other Liabilities OtherLiabilities
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 65771371 | BOY |
| EOY | 80017967 | EOY |
Total Liabilities TotalLiabilities
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 312690617 | BOY |
| EOY | 358085475 | EOY |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Follow SFAS117 | X | FollowSFAS117 |
Unrestricted Net Assets UnrestrictedNetAssets
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | -39862048 | BOY |
| EOY | -80494164 | EOY |
Temporarily Restricted Net Assets TemporarilyRestrictedNetAssets
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | -19053644 | BOY |
| EOY | -7425523 | EOY |
Permanently Restricted Net Assets PermanentlyRestrictedNetAssets
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 1500 | BOY |
| EOY | 2100 | EOY |
Total Net Assets Fund Balances TotalNetAssetsFundBalances
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | -58914192 | BOY |
| EOY | -87917587 | EOY |
Total Liab Net Assets Fund Balances TotalLiabNetAssetsFundBalances
| Field | Value | IRS element (for citing) |
|---|---|---|
| BOY | 253776425 | BOY |
| EOY | 270167888 | EOY |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Info In Schedule O Part XI | X | InfoInScheduleOPartXI |
| Reconcilation Revenue Expenses | -1864564 | ReconcilationRevenueExpenses |
| Reconcilation Other Changes | -27138831 | ReconcilationOtherChanges |
| Info In Schedule O Part XII | X | InfoInScheduleOPartXII |
| Method Of Accounting Accrual | X | MethodOfAccountingAccrual |
| Accountant Compile Or Review | 0 | AccountantCompileOrReview |
| FS Audited | 1 | FSAudited |
| Audit Committee | 1 | AuditCommittee |
| Financial Statement Consolidated | X | FinancialStatementConsolidated |
| Federal Grant Audit Required | 1 | FederalGrantAuditRequired |
| Federal Grant Audit Performed | 1 | FederalGrantAuditPerformed |
Schedule A IRS990ScheduleA
| Field | Value | IRS element (for citing) |
|---|---|---|
| Medical Research Org170b1 Aiii | X | MedicalResearchOrg170b1Aiii |
Hospital Name And Address HospitalNameAndAddress
Name Name
| Field | Value | IRS element (for citing) |
|---|---|---|
| Business Name Line1 | SPECTRUM HEALTH | BusinessNameLine1 |
| Field | Value | IRS element (for citing) |
|---|---|---|
| City | GRAND RAPIDS | City |
| State | MI | State |
Schedule B IRS990ScheduleB
Contributor Info ContributorInfo
| Field | Value | IRS element (for citing) |
|---|---|---|
| Contributor Number | RESTRICTED | ContributorNumber |
Contributor Name Business ContributorNameBusiness
| Field | Value | IRS element (for citing) |
|---|---|---|
| Business Name Line1 | RESTRICTED | BusinessNameLine1 |
Contributor Address US ContributorAddressUS
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | RESTRICTED | AddressLine1 |
| Address Line2 | RESTRICTED | AddressLine2 |
| City | RESTRICTED | City |
| State | RESTRICTED | State |
| ZIP Code | RESTRICTED | ZIPCode |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Aggregate Contributions | RESTRICTED | AggregateContributions |
Schedule C IRS990ScheduleC
| Field | Value | IRS element (for citing) |
|---|---|---|
| Volunteers | 0 | Volunteers |
| Paid Staff Or Management | 1 | PaidStaffOrManagement |
| Media Advertisements | 0 | MediaAdvertisements |
| Mailings Members | 0 | MailingsMembers |
| Publications Or Broadcast | 0 | PublicationsOrBroadcast |
| Grants Other Organizations | 0 | GrantsOtherOrganizations |
| Direct Contact Legislators | 1 | DirectContactLegislators |
| Direct Contact Legislators | $50,000 | DirectContactLegislatorsAmount |
| Rallies Demonstrations | 0 | RalliesDemonstrations |
| Other Activities | 0 | OtherActivities |
| Total Lobbying Expenditures IIB | 50000 | TotalLobbyingExpendituresIIB |
| Not Described In501c3 | 0 | NotDescribedIn501c3 |
Form990 Schedule C Part IV Form990ScheduleCPartIV
| Field | Value | IRS element (for citing) |
|---|---|---|
| Identifier | PART IV, SUPPLEMENTAL INFORMATION: | Identifier |
| Explanation | PAID MANAGEMENT WAS ONLY UTILIZED TO MANAGE RELATIONSHIPS WITH OUTSIDE CONSULTANTS AND DID NOT PARTICIPATE IN DIRECT LOBBYING. THEREFORE, NO COMPENSATION EXPENSE HAS BEEN ALLOCATED TO LOBBYING EXPENSE. | Explanation |
Schedule D IRS990ScheduleD
Art Public Exhibition Amts ArtPublicExhibitionAmts
| Field | Value | IRS element (for citing) |
|---|---|---|
| Assets In Part X | 435037 | AssetsInPartX |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Collect Used For Public Exhibition | X | CollectUsedForPublicExhibition |
| Solicited Assets For Sale | 0 | SolicitedAssetsForSale |
| Endowments Held By Related Orgs | 1 | EndowmentsHeldByRelatedOrgs |
| Are Related Orgs Listed Schedule R | 1 | AreRelatedOrgsListedScheduleR |
Land Land
| Field | Value | IRS element (for citing) |
|---|---|---|
| Other Cost Or Other Basis | 5288315 | OtherCostOrOtherBasis |
| Book Value | 5288315 | BookValue |
Buildings Buildings
| Field | Value | IRS element (for citing) |
|---|---|---|
| Other Cost Or Other Basis | 218665823 | OtherCostOrOtherBasis |
| Depreciation | 26474773 | Depreciation |
| Book Value | 192191050 | BookValue |
Equipment Equipment
| Field | Value | IRS element (for citing) |
|---|---|---|
| Other Cost Or Other Basis | 38310415 | OtherCostOrOtherBasis |
| Depreciation | 26272369 | Depreciation |
| Book Value | 12038046 | BookValue |
Other Land Buildings OtherLandBuildings
| Field | Value | IRS element (for citing) |
|---|---|---|
| Other Cost Or Other Basis | 1392325 | OtherCostOrOtherBasis |
| Depreciation | 29066 | Depreciation |
| Book Value | 1363259 | BookValue |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Of Book Value Land Buildings | 210880670 | TotalOfBookValueLandBuildings |
Other Assets OtherAssets (2 entries)
| DescriptionDescription | Book ValueBookValue |
|---|---|
| BOND ISSUANCE COSTS NET OF ACCUMULATED AMORTIZATION | 1565978 |
| PLEDGED SECURITIES | 48620000 |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Book Value Other Assets | 50185978 | TotalBookValueOtherAssets |
Other Liabilities OtherLiabilities (5 entries)
| DescriptionDescription | AmountAmount |
|---|---|
| ACCRUED POSTRETIREMENT BENEFIT OBLIGATION | $1,364,665 |
| UNREALIZED LOSS ON BOND SWAP | $62,909,361 |
| MSU MED SCHOOL - CONTRIBUTION PAYABLE | $7,696,315 |
| CAPITAL LEASE | $47,626 |
| TGEN - CONTRIBUTION PAYABLE | $8,000,000 |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Of Amounts | 80017967 | TotalOfAmounts |
| Total Revenue | 63688840 | TotalRevenue |
| Total Expenses | 65553404 | TotalExpenses |
| Excess Or Deficit For Year | -1864564 | ExcessOrDeficitForYear |
| Net Unrealized GL On Investments | -251644 | NetUnrealizedGLOnInvestments |
| Other | -$26,887,187 | OtherAmount |
| Total Adjustments | -27138831 | TotalAdjustments |
| Excess Or Deficit Per FS | -29003395 | ExcessOrDeficitPerFS |
| Tot Revenue Etc Audited Fincl Stmt | 59181889 | TotRevenueEtcAuditedFinclStmt |
| Net Unrealized Gains Investments | -251644 | NetUnrealizedGainsInvestments |
| Other Revenues | 18975 | OtherRevenues |
| Revenue Not Rptd F990 | -232669 | RevenueNotRptdF990 |
| Revenue Subtotal | 59414558 | RevenueSubtotal |
| Other Revenues Not Included | 4274282 | OtherRevenuesNotIncluded |
| Revenue Not Rptd On Fin Stmt | 4274282 | RevenueNotRptdOnFinStmt |
| Total Revenue Per Form990 | 63688840 | TotalRevenuePerForm990 |
| Tot Expenses Etc Audited Fincl Stmt | 88185284 | TotExpensesEtcAuditedFinclStmt |
| Other Expenses Included | 26906162 | OtherExpensesIncluded |
| Expenses Not Rptd F990 | 26906162 | ExpensesNotRptdF990 |
| Expenses Subtotal | 61279122 | ExpensesSubtotal |
| Other Expenses Not Included | 4274282 | OtherExpensesNotIncluded |
| Expenses Not Rptd On Fin Stmt | 4274282 | ExpensesNotRptdOnFinStmt |
| Total Expenses Per Form990 | 65553404 | TotalExpensesPerForm990 |
Form990 Schedule D Part XIV Form990ScheduleDPartXIV (6 entries)
| Return ReferenceReturnReference | ExplanationExplanation | IdentifierIdentifier |
|---|---|---|
| PART III, LINE 4: | THE GLASS CHIHULY SCULPTURE IS A UNIQUE, ONE-OF-A-KIND CHANDELIER REMINISCENT OF THE DNA DOUBLE HELIX. THE CHANDELIER, WHICH IS PLACED IN THE RECEPTION AREA, PROVIDES MOTIVATION AND INSPIRATION AS SCIENTISTS ARE DRIVEN TO UNDERSTAND THE GENETIC BASIS OF DISEASES IN THEIR PURSUIT OF CURES AND OTHER THERAPIES. | |
| PART V, LINE 4: | TO SUPPORT THE CORE RESEARCH OF VARI BY SUPPLYING A STEADY SOURCE OF INCOME FOR ITS OPERATING BUDGETS. | DESCRIPTION OF INTENDED USE OF ENDOWMENT FUNDS: |
| PART X: IN JUNE 2006, FASB ISSUED ASC 740, INCOME TAXES (FORMERLY FASB INTERPRETATION (FIN) NO. 48, ACCOUNTING FOR UNCERTAINTY IN INCOME TAXES - AN INTERPRETATION OF FASB STATEMENT NO. 109). ASC 740 PRESCRIBES A RECOGNITION THRESHOLD AND MEASUREMENT ATTRIBUTE FOR THE FINANCIAL STATEMENT RECOGNITION AND MEASUREMENT OF A TAX POSITION TAKEN OR EXPECTED TO BE TAKEN IN A TAX RETURN. ASC 740 ALSO PROVIDES GUIDANCE ON DERECOGNITION, CLASSIFICATION, INTEREST AND PENALTIES, ACCOUNTING FOR INTERIM PERIODS, DISCLOSURE, AND TRANSITION. ASC 740 IS EFFECTIVE FOR FISCAL YEARS BEGINNING AFTER DECEMBER 15, 2008. THIS STANDARD WAS ADOPTED FOR FISCAL YEAR ENDED NOVEMBER 30, 2010. THERE WAS NO MATERIAL IMPACT ON THE CONSOLIDATED FINANCIAL STATEMENTS FOR THE YEAR ENDED NOVEMBER 30, 2011. | ||
| PART XI, LINE 8: NET LOSS RELATED TO THE INTEREST RATE SWAP. PART XII, LINE 2D: RECLASS OF TMS COST OF GOODS SOLD TO PRESENT ON STATEMENT OF REVENUE RATHER THAN STATEMENT OF FUNCTIONAL EXPENSES. PART XIII, LINE 2D: INCLUDES BOTH THE NET LOSS RELATED TO THE INTEREST RATE SWAP AND RECLASS OF TMS COST OF GOODS SOLD TO PRESENT ON STATEMENT OF REVENUE RATHER THAN STATEMENT OF FUNCTIONAL EXPENSES. | ||
| PART XII AND XIII, LINE 4B: EXPENSE ALLOCATIONS | ||
| PART V - ALL ENDOWMENT FUNDS ARE HELD AT THE VAN ANDEL INSTITUTE (A RELATED ORGANIZATION). |
Schedule F IRS990ScheduleF
| Field | Value | IRS element (for citing) |
|---|---|---|
| Grant Records Maintained | 1 | GrantRecordsMaintained |
Accts Actvs Out US Table AcctsActvsOutUSTable
| Field | Value | IRS element (for citing) |
|---|---|---|
| Region | EAST ASIA & THE PACIFIC | Region |
| Number Of Offices | 0 | NumberOfOffices |
| Number Of Employees | 2 | NumberOfEmployees |
| Type Of Activities Conducted | PROGRAM SERVICES | TypeOfActivitiesConducted |
| Specific Services Provided | RESEARCH COLLABORATION - RESEARCH SERVICES | SpecificServicesProvided |
| Total Expenditures | 429197 | TotalExpenditures |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Subtotal Number Of Employees | 2 | SubtotalNumberOfEmployees |
| Cont Number Of Employees | 0 | ContNumberOfEmployees |
| Total Number Of Employees | 2 | TotalNumberOfEmployees |
| Subtotal Amount Spent | 429197 | SubtotalAmountSpent |
| Cont Amount Spent | 0 | ContAmountSpent |
| Total Amount Spent | 429197 | TotalAmountSpent |
| Transfer To Foreign Corp | 0 | TransferToForeignCorp |
| Interest In Foreign Trust | 0 | InterestInForeignTrust |
| Own Foreign Corp | 0 | OwnForeignCorp |
| Passive Foreign Invest Co | 0 | PassiveForeignInvestCo |
| Foreign Partnership | 0 | ForeignPartnership |
| Boycott Countries | 0 | BoycottCountries |
Schedule I IRS990ScheduleI
| Field | Value | IRS element (for citing) |
|---|---|---|
| Records Maintained | 1 | RecordsMaintained |
Form990 Schedule I Part III Form990ScheduleIPartIII (2 entries)
| Type Of GrantTypeOfGrant | Number Of RecipientsNumberOfRecipients | Amount Of Cash GrantAmountOfCashGrant | Amount Of Non Cash AssistanceAmountOfNonCashAssistance | Method Of ValuationMethodOfValuation |
|---|---|---|---|---|
| GRADUATE STUDENT STIPENDS FOR VAN ANDEL GRADUATE SCHOOL AND MICHIGAN STATE UNIVERSITY STUDENTS | 8 | 235354 | 10500 | TUITION PAID |
| FOREIGN NATIONAL STUDENT STIPENDS | 14 | 94971 |
Form990 Schedule I Part IV Form990ScheduleIPartIV
| Field | Value | IRS element (for citing) |
|---|---|---|
| Identifier | OTHER INFORMATION: | Identifier |
| Return Reference | PART IV: | ReturnReference |
| Explanation | SCHEDULE I, PART I, LINE 2: FUNDS PROVIDED TO THE RESEARCH STUDENTS ARE CONTINUALLY MONITORED TO ENSURE THAT ALL FUNDS ARE USED FOR MISSION-DRIVEN PURPOSES. STIPENDS ARE PROVIDED DIRECTLY TO THE STUDENTS FOR LIVING ASSISTANCE. | Explanation |
Schedule J IRS990ScheduleJ
| Field | Value | IRS element (for citing) |
|---|---|---|
| First Class Or Charter Travel | X | FirstClassOrCharterTravel |
| Housing Allowance Or Residence | X | HousingAllowanceOrResidence |
| Club Dues Or Fees | X | ClubDuesOrFees |
| Written Policy Re T And E Expenses | 0 | WrittenPolicyReTAndEExpenses |
| Substantiation Required | 1 | SubstantiationRequired |
| Compensation Committee | X | CompensationCommittee |
| Independent Consultant | X | IndependentConsultant |
| Written Employment Contract | X | WrittenEmploymentContract |
| Compensation Survey | X | CompensationSurvey |
| Board Or Committee Approval | X | BoardOrCommitteeApproval |
| Severance Payment | 1 | SeverancePayment |
| Supplemental Nonqual Retire Plan | 1 | SupplementalNonqualRetirePlan |
| Equity Based Comp Arrangement | 0 | EquityBasedCompArrangement |
| Comp Based On Revenue Of Filing Org | 0 | CompBasedOnRevenueOfFilingOrg |
| Comp Based On Revenue Related Orgs | 0 | CompBasedOnRevenueRelatedOrgs |
| Comp Based Net Earnings Filing Org | 0 | CompBasedNetEarningsFilingOrg |
| Comp Based Net Earnings Relate Orgs | 0 | CompBasedNetEarningsRelateOrgs |
| Any Non Fixed Payments | 0 | AnyNonFixedPayments |
| Initial Contract Exception | 0 | InitialContractException |
Form990 Schedule J Part II Form990ScheduleJPartII (11 entries)
| Base Compensation Filing OrgBaseCompensationFilingOrg | Comp Based On Related OrgsCompBasedOnRelatedOrgs | Bonus Filing OrgBonusFilingOrg | Bonus Related OrgsBonusRelatedOrgs | Other Compensation Filing OrgOtherCompensationFilingOrg | Other Compensation Related OrgsOtherCompensationRelatedOrgs | Deferred Comp Filing OrgDeferredCompFilingOrg | Deferred Comp Related OrgsDeferredCompRelatedOrgs | Nontaxable Benefits Filing OrgNontaxableBenefitsFilingOrg | Nontaxable Benefits Related OrgsNontaxableBenefitsRelatedOrgs | Total Compensation Filing OrgTotalCompensationFilingOrg | Total Compensation Related OrgsTotalCompensationRelatedOrgs | Comp Report Prior990 Filing OrgCompReportPrior990FilingOrg | Comp Report Prior990 Related OrgsCompReportPrior990RelatedOrgs |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DAVID VAN ANDEL | |||||||||||||
| 300014 | 0 | 89284 | 0 | 22952 | 0 | 129426 | 0 | 539 | 0 | 542215 | 0 | 0 | 0 |
| GEORGE VANDE WOUDE | |||||||||||||
| 281791 | 0 | 15000 | 0 | 28972 | 0 | 43022 | 0 | 1323 | 0 | 370108 | 0 | 0 | 0 |
| DR JEFFREY TRENT | |||||||||||||
| 853335 | 0 | 130000 | 0 | 60070 | 0 | 291278 | 0 | 11752 | 0 | 1346435 | 0 | 0 | 0 |
| R JACK FRICK | |||||||||||||
| 217709 | 0 | 45908 | 0 | 1980 | 0 | 92939 | 0 | 8148 | 0 | 366684 | 0 | 0 | 0 |
| TIMOTHY MYERS | |||||||||||||
| 146863 | 0 | 9449 | 0 | 287 | 0 | 82810 | 0 | 8148 | 0 | 247557 | 0 | 0 | 0 |
| KATHLEEN VOGELSANG | |||||||||||||
| 164031 | 0 | 16016 | 0 | 690 | 0 | 27429 | 0 | 8147 | 0 | 216313 | 0 | 0 | 0 |
| DR H ERIC XU | |||||||||||||
| 245796 | 0 | 20985 | 0 | 450 | 0 | 40626 | 0 | 8147 | 0 | 316004 | 0 | 0 | 0 |
| DR JAMES RESAU | |||||||||||||
| 186741 | 0 | 3712 | 0 | 1980 | 0 | 31830 | 0 | 8147 | 0 | 232410 | 0 | 0 | 0 |
| JOHN BENDER | |||||||||||||
| 209861 | 0 | 10000 | 0 | 13379 | 0 | 23455 | 0 | 8148 | 0 | 264843 | 0 | 0 | 0 |
| BRYON CAMPBELL | |||||||||||||
| 172363 | 0 | 6445 | 0 | 690 | 0 | 27410 | 0 | 8147 | 0 | 215055 | 0 | 0 | 0 |
| STEVE HEACOCK FORMER | |||||||||||||
| 90579 | 0 | 60371 | 0 | 464169 | 0 | 18751 | 0 | 4344 | 0 | 638214 | 0 | 0 | 0 |
Form990 Schedule J Part III Form990ScheduleJPartIII (3 entries)
| Return ReferenceReturnReference | ExplanationExplanation | IdentifierIdentifier |
|---|---|---|
| PART I, LINE 1A | VARI ALLOWS FOR FIRST-CLASS OR CHARTER TRAVEL TO OFFICERS AND TRUSTEES. FITNESS CENTER MEMBERSHIP DUES WERE PAID BY VARI FOR STEVE HEACOCK TOTALING $500 FOR CALENDAR YEAR 2010. PART I, LINE 1B: THERE IS NOT A POLICY FOR HOUSING ALLOWANCE OR RESIDENCE FOR PERSONAL USE. THIS IS OFFERED ONLY ON RARE OCCASIONS AND FOR SPECIAL CIRCUMSTANCES. HUMAN RESOURCES MANAGES THIS ON A CASE BY CASE BASIS. | |
| PART I, LINE 1B | A WRITTEN POLICY IS IN PLACE FOR FIRST CLASS/ CHARTER TRAVEL AND HEALTH/ SOCIAL CLUB DUES/ FEES. | |
| PART III | PART I, LINE 4A: SEVERANCE PAID TO STEVE HEACOCK TOTALED $0 IN FISCAL YEAR 2011, $448,871 IN CALENDAR YEAR 2010 PART I, LINE 4B: STEVE HEACOCK $0 FOR FISCAL YEAR 2011 AND $3,808 CALENDAR YEAR 2010 GEORGE VANDE WOUDE $16,500 FISCAL YEAR 2011 AND CALENDAR YEAR 2010 | SUPPLEMENTAL INFORMATION |
Schedule K IRS990ScheduleK
Form990 Schedule K Part I Form990ScheduleKPartI
Issuer Name IssuerName
| Field | Value | IRS element (for citing) |
|---|---|---|
| Business Name Line1 | MICHIGAN STRATEGIC FUND LIMITED OBLIGATION REVENUE | BusinessNameLine1 |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Issuer EIN | 521417332 | IssuerEIN |
| CUSIP Number | 594698EG3 | CUSIPNumber |
| Date Issued | 2008-04-10 | DateIssued |
| Issue Price | 220000000 | IssuePrice |
| Description Of Purpose | BUILD, EQUIP & FURNISH PHASE II RESEARCH FACILITY, & REFUND $50M PRIOR LTD | DescriptionOfPurpose |
| Defeased | 0 | Defeased |
| On Behalf Of Issuer | 0 | OnBehalfOfIssuer |
| Pool Financing | 0 | PoolFinancing |
Form990 Schedule K Part II Form990ScheduleKPartII
| Field | Value | IRS element (for citing) |
|---|---|---|
| Total Proceeds | 223154512 | TotalProceeds |
| Capital Expenditures | 113036720 | CapitalExpenditures |
| Other Spent Proceeds | 110117792 | OtherSpentProceeds |
| Year Of Subst Completion | 2009 | YearOfSubstCompletion |
| Current Refunding | 1 | CurrentRefunding |
| Advance Refunding | 0 | AdvanceRefunding |
| Final Allocation Made | 1 | FinalAllocationMade |
| Adequate Books And Recds Maintaind | 1 | AdequateBooksAndRecdsMaintaind |
Form990 Schedule K Part III Form990ScheduleKPartIII
| Field | Value | IRS element (for citing) |
|---|---|---|
| Owning Bond Financed Property | 0 | OwningBondFinancedProperty |
| Any Lease Arrangements | 1 | AnyLeaseArrangements |
| Mngment Cntrct Bond Financd Prprty | 1 | MngmentCntrctBondFinancdPrprty |
| Any Research Agreements | 1 | AnyResearchAgreements |
| Bond Counsel Routinely Engaged | 1 | BondCounselRoutinelyEngaged |
| Percentage Of Prvt Business Re UBI | 0.00860 | PercentageOfPrvtBusinessReUBI |
| Total Private Business Use | 0.00860 | TotalPrivateBusinessUse |
| Post Issuance Compliance Procdrs | 1 | PostIssuanceComplianceProcdrs |
Form990 Schedule K Part IV Form990ScheduleKPartIV
| Field | Value | IRS element (for citing) |
|---|---|---|
| Form8038 T Filed | 1 | Form8038TFiled |
| Variable Rate Issue | 1 | VariableRateIssue |
| Hedge Identified In Books And Recds | 0 | HedgeIdentifiedInBooksAndRecds |
| Gross Proceeds Invested In GIC | 0 | GrossProceedsInvestedInGIC |
| Gross Proceeds Invested | 0 | GrossProceedsInvested |
| Exception To Rebate | 0 | ExceptionToRebate |
Schedule O IRS990ScheduleO
General Explanation GeneralExplanation (17 entries)
| IdentifierIdentifier | ExplanationExplanation | Return ReferenceReturnReference |
|---|---|---|
| FORM 990, PART VI, SECTION A, LINE 2 | VARI AND VAEI SHARE COMMON MANAGEMENT. AS OFFICERS OF VARI, DAVID VAN ANDEL, R. JACK FRICK, TIMOTHY MYERS AND DAVID WHITESCARVER INTERACT AND WORK TOGETHER WITH STEVE TRIEZENBERG, A KEY EMPLOYEE OF VAEI. | |
| FORM 990, PART VI, SECTION A, LINE 3 | JERRY CALLAHAN, AN INDEPENDENT CONTRACTOR, SERVES AS THE VICE PRESIDENT OF BUSINESS DEVELOPMENT, TECHNOLOGY TRANSFER, AND OFFICE OF GRANTS AND CONTRACTS. | |
| FORM 990, PART VI, SECTION A, LINE 7A | THE TRUSTEES OF VAN ANDEL INSTITUTE HAVE THE AUTHORITY TO ELECT ONE OR MORE MEMBERS OF VARI'S GOVERNING BODY. | |
| FORM 990, PART VI, SECTION B, LINE 11 | FOLLOWING COMPLETION OF THE FINANCIAL AUDIT, THE FORM 990 IS PREPARED AND REVIEWED BY MANAGEMENT. IT IS THEN CIRCULATED TO THE FULL BOARD FOR REVIEW AND FINAL APPROVAL PRIOR TO FILING WITH THE IRS. | |
| VARI HAS A WRITTEN CONFLICT OF INTEREST POLICY FOR WHICH THE ORGANIZATION ENFORCES A PROCESS TO IDENTIFY, EVALUATE, AND CORRECT OR REMOVE POTENTIAL CONFLICTS OF INTEREST. THE VAN ANDEL INSTITUTE ADMINISTERS THE CONFLICT OF INTEREST (COI) POLICY THROUGH TWO COMMITTEES: THE INDIVIDUAL COI COMMITTEE AND THE INSTITUTIONAL COI COMMITTEE. THE COI POLICY SERVES AS GUIDE FOR ALL STAFF MEMBERS OF THE ORGANIZATION. THE POLICY IS INTENDED TO 1) PROVIDE STAFF WITH A USEFUL RESOURCE WHEN DEVELOPING ACTIVITIES WITH OUTSIDE INDUSTRY AND 2) PROVIDE ASSURANCE TO STAFF THAT THERE IS A COMMITTEE TO REVIEW AND RESOLVE POTENTIAL CONFLICTS OF INTEREST IF / WHEN THEY ARISE. THE INDIVIDUAL COI COMMITTEE, CHAIRED BY THE DIRECTOR OF COMPLIANCE, GENERATES AN ANNUAL DISCLOSURE QUESTIONNAIRE DISTRIBUTED TO ALL STAFF TO ENFORCE THE POLICY. THE CONFLICTS COMMITTEE IS RESPONSIBLE FOR MAKING RECOMMENDATIONS TO THE DIRECTOR. RESOLUTIONS ARE IMPLEMENTED WITH APPROVAL OF THE COMMITTEE AND IN DISCUSSION WITH THE VAI CHAIRMAN. THE COI POLICY ALSO SERVES AS A GUIDE FOR ALL MEMBERS OF THE BOARD OF TRUSTEES AND SENIOR EXECUTIVES. THE INSTITUTIONAL COI COMMITTEE REQUIRES TRUSTEES TO COMPLETE AN ANNUAL DISCLOSURE STATEMENT. THIS STATEMENT AFFIRMS THEIR UNDERSTANDING OF THE POLICY, REQUIRES THEIR ACKNOWLEDGEMENT OF THE ORGANIZATION'S NONPROFIT STATUS, AND REQUESTS DISCLOSURE IF / WHEN POTENTIAL CONFLICTS ARISE. IN THE EVENT A POTENTIAL CONFLICT ARISES AT THE BOARD OR SENIOR OFFICER LEVEL, THE OFFICE OF THE GENERAL COUNSEL REVIEWS AND MEETS WITH THE BOARD OF TRUSTEES TO RESOLVE POTENTIAL CONFLICTS. | FORM 990, PART VI, SECTION B, LINE 12 | |
| COMPENSATION FOR THE CEO, EXECUTIVE MANAGEMENT OFFICIALS, EXECUTIVE DIRECTOR, OFFICERS, AND KEY EMPLOYEES IS REVIEWED AND APPROVED ANNUALLY BY THE VAN ANDEL INSTITUTE'S INDEPENDENT COMPENSATION COMMITTEE. RECORDS AND DOCUMENTATION, INCLUDING COMPARABILITY DATA, ARE KEPT AND SUPPORT DECISIONS MADE ON BEHALF OF THESE ARRANGEMENTS AND ARE CONTEMPORANEOUSLY DOCUMENTED. | FORM 990, PART VI, SECTION B, LINE 15 | |
| THESE DOCUMENTS ARE AVAILABLE TO THE PUBLIC UPON REQUEST. | FORM 990, PART VI, SECTION C, LINE 19 | |
| COMPENSATION FOR HUNT - OWEN AMES & KIMBALL EXCLUDES ESTIMATED MATERIALS AND INCLUDES ESTIMATED LABOR ON HUNT MANAGED SUB-CONTRACTORS. | FORM 990, PART VII, SECTION B | |
| JEFFREY BATTERSHALL IS LISTED AS SECRETARY ON PAGE 7. HE SERVED ON AN INTERIM BASIS AND WAS CONTRACTED FOR THIS PURPOSE THROUGH THE LAW FIRM WARNER, NORCROSS, & JUDD THROUGH OCTOBER 2011. ALL PAYMENTS FOR HIS SERVICES WERE PAID DIRECTLY TO WARNER, NORCROSS, & JUDD. | FORM 990, PART VII, SECTION B | |
| DAVID VAN ANDEL, R. JACK FRICK, TIMOTHY MYERS, JEFFREY BATTERSHALL, AND DAVID WHITESCARVER ALSO PERFORMED WORK FOR VAN ANDEL INSTITUTE, VAN ANDEL EDUCATION INSTITUTE, AND VAN ANDEL INSTITUTE GRADUATE SCHOOL (RELATED ENTITIES). | FORM 990, PART VII, PAGE 7 | |
| CHANGES IN NET ASSETS OR FUND BALANCES: | NET UNREALIZED LOSSES ON INVESTMENTS: -251,644. LOSS ON BOND INTEREST SWAP -26,887,187. TOTAL TO FORM 990, PART XI, LINE 5: -27,138,831. | FORM 990, PART XI, LINE 5: |
| THE PROCESS FOR SELECTING THE AUDITOR FOR VAN ANDEL RESEARCH INSTITUTE'S FINANCIAL STATEMENTS DID NOT CHANGE DURING 2011. | FORM 990, PART XII, LINE 2C | |
| VARI'S THREE LARGEST PROGRAM SERVICES BY EXPENSES | LINE 4A - PROGRAM SERVICE ACTIVITY #1 THE LABORATORY OF STRUCTURAL SCIENCES IS FOCUSED ON STUDYING THE STRUCTURES AND FUNCTIONS OF PROTEIN/ LIGAND COMPLEXES THAT PLAY KEY ROLES IN MAJOR HORMONE SIGNALING PATHWAYS. THE LABORATORY ALSO WORKS ON EXPLORING THE STRUCTURAL INFORMATION TO DEVELOP THERAPEUTIC AGENTS FOR TREATING HUMAN DISEASE, INCLUDING CANCER AND DIABETES. LAB STUDIES USE MULTIDISCIPLINARY APPROACHES, INCLUDING MOLECULAR AND CELLULAR BIOLOGY, BIOCHEMISTRY, ANIMAL PHYSIOLOGY, X-RAY CRYSTALLOGRAPHY, AND PLANT HORMONE ABSCISIC ACID (ABA) RECEPTORS. RESEARCH IN THIS GROUP CURRENTLY FOCUSES ON THREE AREAS: NUCLEAR HORMONE RECEPTORS, THE MET TYROSINE KINASE RECEPTOR, AND G PROTEIN-COUPLED RECEPTORS. THESE PROTEINS, BEYOND THEIR FUNDAMENTAL ROLES IN BIOLOGY, ARE IMPORTANT DRUG TARGETS. RECENT DISCOVERIES INCLUDE: THE CRYSTAL STRUCTURES OF EACH PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) LIGAND-BINDING DOMAIN (LBD) BOUND TO MANY DIVERSE LIGANDS IN ORDER TO UNDERSTAND THE MOLECULAR BASIS OF LIGAND-MEDIATED SIGNALING BY PPAR'S; THE CRYSTAL STRUCTURES OF THE RECEPTORS BOUND TO COACTIVATORS OR CO-REPRESSORS, WHICH PROVIDES A FRAMEWORK FOR UNDERSTANDING THE MECHANISMS OF PPAR AGONISTS AND ANTAGONIST AND THE RECRUITMENT OF COACTIVATORS AND CO-REPRESSORS; ANDROGEN RECEPTOR (AR) MUTATION IN PROSTATE CANCERS OFTEN RESULTS IN ENHANCED BINDING TO A PARTICULAR COACTIVATOR, SRC-3 (WHICH IS ALSO CALLED "AMPLIFIED IN BREAST CANCER1", OR AIB1); AND RETINOIC ACID IS A LOW-AFFINITY LIGAND FOR COUP-TF, WHICH IS ONE OF THE MOST CONSERVED NUCLEAR RECEPTORS AND HAS ESSENTIAL ROLES IN ANGIOGENESIS, HEART DEVELOPMENT, CNS ACTIVITY, AND METABOLIC HOMEOSTASIS. LINE 4B - PROGRAM SERVICE ACTIVITY #2 SINCE DISCOVERING THE C-MET RECEPTOR AND ITS LIGAND HEPATOCYTE GROWTH FACTOR (HGF/SF) IN THE MID-1980S, THE LABORATORY OF MOLECULAR ONCOLOGY HAS FOCUSED ON INVESTIGATING THE PARAMOUNT ROLE THESE PROTEINS PLAY IN MALIGNANT PROGRESSION AND METASTASIS. MET IS OVEREXPRESSED IN MANY TYPES OF HUMAN CANCER, AND ITS EXPRESSION CORRELATES WITH AN AGGRESSIVE DISEASE AND POOR PROGNOSIS (HTTP://WWW.VAI.ORG/MET/). THE MAJOR ADVANCES MADE IN THE PAST DECADE IN UNDERSTANDING HGF/SF-MET CELLULAR SIGNALING HAVE PROVIDED POWERFUL RATIONALE FOR THE DEVELOPMENT OF INHIBITORS TARGETING IT. SEVERAL OF THESE INNOVATIVE INHIBITORS ARE CURRENTLY BEING EVALUATED IN CLINICAL TRIALS (HTTP://WWW.VAI.ORG/METCLINICALTRIALS/). THE ABERRANT EXPRESSION OF MET IN MANY HUMAN TUMORS ALSO NECESSITATED THE DEVELOPMENT OF COMPANION DIAGNOSTICS TO IDENTIFY THOSE PATIENTS WHO COULD BENEFIT FROM MET TARGETED THERAPIES. IN COLLABORATION WITH DR. BRIAN CAO, WE HAVE DEVELOPED A MONOCLONAL ANTIBODY (DESIGNATED MET4), WHICH WE BELIEVE WILL PROVE VALUABLE AS A DIAGNOSTIC REAGENT AS WELL AS AN ESSENTIAL RESEARCH TOOL. AS PART OF THE ONGOING EFFORT TO FURTHER ENHANCE OUR UNDERSTATING OF THE HGF/SF-MET SIGNALING SYSTEM, OUR LAB CURRENTLY FOCUSES ON THE PROJECTS DESCRIBED BELOW: -CONTINUING TO DEVELOP AND CHARACTERIZE NOVEL RESEARCH MODELS FOR A VARIETY OF HUMAN CANCERS (LIVER, BRAIN, BREAST, LUNG AND OTHERS) AND USING THEM IN PRE-CLINICAL EVALUATION OF NEW C-MET INHIBITORS AS WELL AS OTHER THERAPEUTIC STRATEGIES -EVALUATING HGF AUTOCRINE AS A THERAPEUTIC MARKER PREDICTING SENSITIVITY TO C-MET INHIBITION USING VARIOUS GLIOBLASTOMA AND HEPATOCELLULAR CARCINOMA MODELS -INVESTIGATING THE UNIQUE ROLES THAT C-MET AND ERBB2 PLAY IN THE PROGRESSION AND METASTASIS OF AGGRESSIVE BREAST CANCERS -STUDYING THE MECHANISMS RESPONSIBLE FOR PHENOTYPIC SWITCHING (E-MT/M-ET) AND EVALUATING THE ROLE OF CHROMOSOME INSTABILITY IN TUMOR PROGRESSION -DETERMINING THE TUMOR SUPPRESSOR ROLE OF MIG-6 AS WELL AS INVESTIGATING THE MOLECULAR MECHANISM UNDERLYING ITS FUNCTION IN BOTH CANCER AND OSTEOARTHRITIS LINE 4C - PROGRAM SERVICE ACTIVITY #3 THE LABORATORY OF TRANSLATIONAL MEDICINE (LTM) IS FOCUSED ON TWO CRITICAL AREAS OF CANCER RESEARCH. AT THE BASIC SCIENCE LEVEL, THE LAB IS UTILIZING A RANGE OF MOLECULAR AND COMPUTATIONAL TECHNOLOGIES TO STUDY HOW TUMORS SPREAD TO DISTANT PARTS OF THE BODY FROM ITS ORIGINAL LOCATION - THIS PROCESS, KNOWN AS METASTASIS, IS ACCOUNTABLE FOR >90% OF CANCER RELATED DEATHS, AND THE IDENTIFICATION OF NEW DIAGNOSTIC AND TREATMENT STRATEGIES TARGETING THIS LETHAL PHENOTYPE OF CANCER ARE OF UTTERMOST IMPORTANCE. IN THE AREA OF APPLIED RESEARCH, THE LTM IS FOCUSED ON DEVELOPING AND IMPLEMENTING STRATEGIES TO "PERSONALIZE" THE TREATMENT OF A RANGE OF AGGRESSIVE CANCERS WITH MOLECULARLY-GUIDED THERAPIES. THE LTM CONTINUES TO BE AT THE FOREFRONT OF DESIGNING AND IMPLEMENTING APPROACHES IN WHICH THE TREATMENT OF AN INDIVIDUAL PATIENT'S CANCER IS BASED UPON THE MOLECULAR ANALYSIS OF THAT PATIENT AND THEIR SPECIFIC DISEASE. TO FACILITATE THIS, THE LAB DESIGNED AND DEVELOPED AN INTEGRATED, BIOMEDICAL INFORMATICS SYSTEM FOR DATA MANAGEMENT, ANALYSIS, AND REPORTING (KNOWN AS XENOBASE BIOINTEGRATION SUITE (XB-BIS)). IN ADDITION, THE LAB HAS BEEN HEAVILY INVOLVED IN COMMUNITY FOUNDING PARTNERSHIPS THAT HAVE INCLUDED THE FORMATION OF A BIOMARKER-DRIVEN CLINICAL TRIALS CONSORTIUM (CLINXUS), A HIGH COMPLEXITY CLIA CERTIFIED LABORATORY (THE CENTER FOR MOLECULAR MEDICINE), AND A PERSONALIZED MEDICINE INFORMATION SERVICE COMPANY (INTERVENTION INSIGHTS) WHICH COLLECTIVELY, PERMIT THE APPLICATION OF PERSONALIZED THERAPY FOR LATE STAGE CANCER PATIENTS. RECENT ACCOMPLISHMENTS INCLUDE THE DEVELOPMENT AND COMMERCIALIZATION OF AN INTEGRATED INFORMATICS SOLUTION (XB-BIS), WHICH ENABLES EFFICIENT EXCHANGE OF INFORMATION BETWEEN THE BASIC RESEARCH LABORATORY AND THE CLINIC FOR EFFECTIVE TRANSLATIONAL RESEARCH. XB-BIS HAS BEEN LICENSED TO TRANSMED SYSTEMS WHICH IS NOW SUPPORTING ITS ADOPTION ACROSS MULTIPLE GROUPS ENGAGED IN TRANSLATIONAL RESEARCH BOTH WITHIN THE UNITED STATES AND BEYOND. IN PART THROUGH THE USE OF XB-BIS, THE LAB RECENTLY COMPLETED A FEASIBILITY STUDY OF 50 LATE-STAGE PEDIATRIC AND ADULT CANCER PATIENTS IN WHICH TUMOR-DERIVED GENE EXPRESSION PROFILES WERE ANALYZED TO IDENTIFY POTENTIAL DRUGS TO TARGET PERTURBED MOLECULAR COMPONENTS OF EACH PATIENT'S SPECIFIC TUMOR. ANECDOTAL SIGNS OF SUCCESS IN A HANDFUL OF PATIENTS PROVIDED THE IMPETUS TO LAUNCH A SERIES OF FOLLOW-UP STUDIES WITHIN FOCUSED PATIENT POPULATIONS, AND ALSO LED TO THE FORMATION OF INTERVENTION INSIGHTS, A PERSONALIZED MEDICINE INFORMATION SERVICE THAT SUPPORTS COMMUNITY AND ACADEMIC ONCOLOGISTS ACROSS THE UNITED STATES. AT VARI, THE LTM CONTINUES TO ADVANCE THE MOLECULAR AND COMPUTATIONAL TECHNOLOGIES AND IS CURRENTLY INVESTIGATING THE POTENTIAL USE OF NEXT GENERATION SEQUENCING TECHNOLOGIES IN TARGETED TRIALS OF NEUROBLASTOMA (SPONSORED BY THE NEUROBLASTOMA AND MEDULLOBLASTOMA TRANSLATIONAL RESEARCH CONSORTIUM (NMTRC) AND IN PARTNERSHIP WITH DELL AND INTERVENTION INSIGHTS), METASTATIC MELANOMA (SPONSORED BY A RECENT STAND UP 2 CANCER GRANT), TRIPLE NEGATIVE BREAST CANCER (SPONSORED BY A KOMEN PROMISE GRANT), AND GLIOBLASTOMA (SPONSORED BY HENRY FORD HOSPITAL AND A RECENT NIH GRANT). | FORM 990, PART III, LINES 4A-4C |
| ALL OTHER PROGRAM SERVICE ACTIVITIES IN 2011, VARI RESEARCHERS FOUND WAYS TO POTENTIALLY DIAGNOSE AND FIGHT SEVERAL DIFFERENT TYPES OF CANCER. IN 2011, VARI ALSO ANNOUNCED A PATENT WITH GENTEL BIOSCIENCES, A LEADER IN PROTEOMICS TOOLS, FOR A NEW APPROACH TO IDENTIFY BIOLOGICAL MARKERS TO HELP DIAGNOSE DISEASES SUCH AS CANCER. BELOW ARE OTHER EXAMPLES OF SIGNIFICANT RESEARCH FINDINGS: -VARI ANNOUNCED THE CREATION OF THE VARI PEDIATRIC CANCER TRANSLATIONAL RESEARCH PROGRAM, A PROJECT THAT UNITES BASIC RESEARCH AND CLINICAL CARE THROUGH A NATIONWIDE CONSORTIUM OF PARTNERS. -RESEARCHERS DETERMINED HOW THE ANTI-CANCER ANTIBIOTIC GELDANAMYCIN AND ITS DERIVATIVE 17AAG WORK IN MORE DETAIL AND HAVE UNCOVERED A POSSIBLE EXPLANATION FOR SIDE EFFECTS, WHICH COULD INFORM FUTURE DRUG DESIGN. -RESEARCHERS IDENTIFIED MK-STYX AS AN ENZYME THAT HELPS TO REGULATE CELL DEATH, AND FOUND OUT MORE ABOUT SPECIFICALLY HOW MK-STYX WORKS. -RESEARCHERS IDENTIFIED THE GENE POLO-LIKE KINASE 1 (PLK1) AS A NEW POTENTIAL DRUG TARGET TO TREAT CLEAR CELL RENAL CELL CARCINOMA (CCRCC), THE MOST COMMON FORM OF KIDNEY CANCER. THEY ALSO FOUND THAT THE PLK1 INHIBITOR BI 2536, CURRENTLY IN CLINICAL TRIALS FOR THE TREATMENT OF SEVERAL CANCERS, LED TO DRAMATIC REGRESSION OF CCRCC TUMORS. -RESEARCHERS IDENTIFIED AN ENZYME, LRRK2, THAT SEEMS TO COOPERATE WITH MET, AN IMPORTANT GENE IN SEVERAL CANCERS, TO PROMOTE TUMOR CELL GROWTH AND SURVIVAL, SPECIFICALLY IN PAPILLARY RENAL AND THYROID CARCINOMAS. -RESEARCHERS IDENTIFIED SPECIFIC PROTEINS THAT CARRY THE CA 19-9, THE BEST INDICATOR OF PANCREATIC CANCER, ANTIGEN AND MEASURED CA 19-9 LEVELS ON EACH PROTEIN IN AN EFFORT TO ENHANCE BLOOD TESTING. BETTER KNOWLEDGE OF THESE CARRIERS IN VARIOUS DISEASE STATES COULD LEAD TO IMPROVED DIAGNOSTIC TESTS. -RESEARCHERS INVESTIGATED THE ROLE OF THE PROTEIN HEPATOMA-DERIVED GROWTH FACTOR (HDGF) IN BREAST AND PROSTATE CANCERS AND FOUND THAT IT MAY PROMOTE CELL GROWTH IN THESE CANCERS AND COULD BE A THERAPEUTIC TARGET. -RESEARCHERS FOUND THAT IN SK-MEL-28 MELANOMA CELLS, MEK2, AND NOT MEK1, IS SUFFICIENT FOR CELL PROLIFERATION, BUT THAT MEK1 CAN COMPENSATE FOR THE LOSS OF MEK2 ACTIVITY. THESE INSIGHTS MAY AID IN THE DESIGN OF MORE EFFECTIVE THERAPIES FOR TREATING MELANOMA AND OTHER MEK-DEPENDENT CANCERS. -IN COLLABORATION WITH RESEARCHERS FROM ANOTHER ORGANIZATION, RESEARCHERS IDENTIFIED A NOVEL MARKER THAT COULD HELP DIAGNOSE TYPE II EATL, WHICH IS THE TYPE MORE COMMON IN ASIA AND NOT ASSOCIATED WITH COELIAC DISEASE. -IN ADDITION TO THOSE LISTED ABOVE, THERE WERE ALSO FINDINGS WITHIN MELANOMA, BRAIN CANCER, HEAD AND NECK CANCER, ALZHEIMER'S DIABETES, AUTOIMMUNE DISEASE, RETINOPATHY, AND HOOKWORM. | FORM 990, PART III, LINE 4D | |
| VARI NET ASSETS SHOULD BE CONSIDERED ON A CONSOLIDATED BASIS WITH VAN ANDEL INSTITUTE (VAI), VAN ANDEL EDUCATION INSTITUTE (VAEI), AND THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN), RELATED PARTIES. ON A CONSOLIDATED BASIS, NET ASSETS ARE $896,445,000 PER AUDITED FINANCIAL STATEMENTS. THE NEGATIVE NET ASSETS AT VARI ARE DUE TO VAI FUNDING EXPENSES ON A CASH BASIS AND GUARANTEEING VARI'S LONG-TERM DEBT AND UNREALIZED BOND SWAP LOSS. | FORM 990, PART X, LINE 33 | |
| FUNDRAISING EXPENSES AT VARI WERE INCURRED TO SUPPORT THE MISSION OF THE RESEARCH INSTITUTE THROUGH GRANT SOLICITATION AND EXTRAMURAL PROPOSAL PREPARATION. | FORM 990, PART IX, COLUMN D | |
| THE INSTITUTE DOES HAVE A WRITTEN CONFLICT OF INTEREST POLICY, A WRITTEN WHISTLEBLOWER POLICY, AND A WRITTEN DOCUMENT RETENTION POLICY; HOWEVER, IS REQUIRED TO CHECK NO BASED ON THE IRS INSTRUCTIONS AS THESE POLICIES HAVE NOT BEEN OFFICIALLY APPROVED BY OUR BOARD. | FORM 990, PART VI, LINES 12-14 |
Schedule R IRS990ScheduleR
Form990 Schedule R Part I Form990ScheduleRPartI (4 entries)
| Address Line1AddressUS/AddressLine1 | CityAddressUS/City | StateAddressUS/State | ZIP CodeAddressUS/ZIPCode | EINEIN | Primary ActivitiesPrimaryActivities | Legal Domicile StateLegalDomicileState | Total IncomeTotalIncome | EOY AssetsEOYAssets | Business Name Line1DirectControllingEntityName/BusinessNameLine1 |
|---|---|---|---|---|---|---|---|---|---|
| VAI INNOVATIONS LLC | |||||||||
| 333 BOSTWICK AVENUE NE | GRAND RAPIDS | MI | 495032518 | 522000823 | LICENSING INTELLECTUAL PROPERTY OF VARI | MI | -677549 | 10457 | VAN ANDEL RESEARCH INSTITUTE |
| VARI INTERNATIONAL | |||||||||
| 333 BOSTWICK AVENUE NE | GRAND RAPIDS | MI | 495032518 | 262615936 | BIOMEDICAL RESEARCH | MI | -27104 | 172207 | VAN ANDEL RESEARCH INSTITUTE |
| BOSTWICK EVENT MANAGEMENT | |||||||||
| 333 BOSTWICK AVENUE NE | GRAND RAPIDS | MI | 495032518 | 522000823 | EVENT MANAGEMENT | MI | -74494 | 561 | VAN ANDEL RESEARCH INSTITUTE |
| VARI-CLINXUS LLC | |||||||||
| 333 BOSTWICK AVENUE NE | GRAND RAPIDS | MI | 495032518 | 274015168 | CLINICAL TRIALS | MI | -47858 | 80282 | VAN ANDEL RESEARCH INSTITUTE |
Form990 Schedule R Part II Form990ScheduleRPartII (5 entries)
| Address Line1AddressUS/AddressLine1 | CityAddressUS/City | StateAddressUS/State | ZIP CodeAddressUS/ZIPCode | EINEIN | Primary ActivitiesPrimaryActivities | Legal Domicile StateLegalDomicileState | Exempt Code SectionExemptCodeSection | Public Charity StatusPublicCharityStatus | Direct Controlling Entity NADirectControllingEntityNA | Controlled OrgControlledOrg | Business Name Line1DirectControllingEntityName/BusinessNameLine1 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| VAN ANDEL INSTITUTE | |||||||||||
| 333 BOSTWICK AVENUE NE | GRAND RAPIDS | MI | 495032518 | 522000820 | SUPPORTING ORGANIZATION FOR VARI AND VAEI | MI | 501(C)(3) | 11C | N/A | 0 | |
| VAN ANDEL EDUCATION INSTITUTE | |||||||||||
| 333 BOSTWICK AVENUE NE | GRAND RAPIDS | MI | 495032518 | 522000824 | OPERATING A SCHOOL | MI | 501(C)(3) | 2 | 1 | VAN ANDEL INSTITUTE | |
| VAN ANDEL INSTITUTE GRADUATE SCHOOL | |||||||||||
| 333 BOSTWICK AVENUE NE | GRAND RAPIDS | ME | 495032518 | 203340886 | OPERATING A SCHOOL | MI | 501(C)(3) | 2 | 1 | VAN ANDEL EDUCATION INSTITUTE | |
| THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE | |||||||||||
| 445 N 5TH STREET SUITE 600 | PHOENIX | AZ | 85004 | 753065445 | MEDICAL RESEARCH | AZ | 501(C)(3) | 7 | 1 | VAN ANDEL RESEARCH INSTITUTE | |
| TGEN RESEARCH INSTITUTE FOUNDATION | |||||||||||
| 400 E VAN BUREN SUITE 850 | PHOENIX | AZ | 85004 | 331092191 | FUNDRAISING | AZ | 501(C)(3) | 7 | 1 | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE | |
Form990 Schedule R Part IV Form990ScheduleRPartIV
Name Of Related Org NameOfRelatedOrg
| Field | Value | IRS element (for citing) |
|---|---|---|
| Business Name Line1 | TRANSMED SYSTEMS INC | BusinessNameLine1 |
Address US AddressUS
| Field | Value | IRS element (for citing) |
|---|---|---|
| Address Line1 | 21170 CANYON OAK WAY | AddressLine1 |
| City | CUPERTINO | City |
| State | CA | State |
| ZIP Code | 95014 | ZIPCode |
| Field | Value | IRS element (for citing) |
|---|---|---|
| EIN | 272358859 | EIN |
| Primary Activity | TRANSLATIONAL MEDICAL SOFTWARE AND SERVICES | PrimaryActivity |
| Legal Domicile State | CA | LegalDomicileState |
Direct Controlling Entity Name DirectControllingEntityName
| Field | Value | IRS element (for citing) |
|---|---|---|
| Business Name Line1 | VAI INNOVATIONS LLC | BusinessNameLine1 |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Type Of Entity | C | TypeOfEntity |
| Share Of Total Income | -697483 | ShareOfTotalIncome |
| Share Of EOY Assets | 478524 | ShareOfEOYAssets |
| Percentage Ownership | 0.55900 | PercentageOwnership |
| Field | Value | IRS element (for citing) |
|---|---|---|
| Receipt Of Int Ann Rents Royalties | 1 | ReceiptOfIntAnnRentsRoyalties |
| Gift Grant Or Cap Contr To Other Org | 1 | GiftGrantOrCapContrToOtherOrg |
| Gift Grant Or Cap Contr Fr Other Org | 1 | GiftGrantOrCapContrFrOtherOrg |
| Loans Or Guarantees To Other Org | 0 | LoansOrGuaranteesToOtherOrg |
| Loans Or Guarantees From Other Org | 1 | LoansOrGuaranteesFromOtherOrg |
| Sale Of Assets To Other Org | 1 | SaleOfAssetsToOtherOrg |
| Purchase Of Assets From Other Org | 0 | PurchaseOfAssetsFromOtherOrg |
| Exchange Of Assets | 0 | ExchangeOfAssets |
| Rental Of Facilities To Other Orgs | 0 | RentalOfFacilitiesToOtherOrgs |
| Rental Of Facilities Fr Other Orgs | 0 | RentalOfFacilitiesFrOtherOrgs |
| Perform Of Services For Other Orgs | 1 | PerformOfServicesForOtherOrgs |
| Perform Of Services By Other Orgs | 0 | PerformOfServicesByOtherOrgs |
| Sharing Of Facilities | 1 | SharingOfFacilities |
| Sharing Of Paid Employees | 1 | SharingOfPaidEmployees |
| Reimbursement Paid To Other Org | 1 | ReimbursementPaidToOtherOrg |
| Reimbursement Paid By Other Org | 1 | ReimbursementPaidByOtherOrg |
| Other Transfer To Other Org | 1 | OtherTransferToOtherOrg |
| Other Transfer From Other Org | 0 | OtherTransferFromOtherOrg |
Transactions Related Orgs Table TransactionsRelatedOrgsTable (18 entries)
| Transaction TypeTransactionType | Amount InvolvedAmountInvolved | Method Of Amt DeterminationMethodOfAmtDetermination |
|---|---|---|
| VAN ANDEL INSTITUTE | ||
| C | 47313999 | ACTUAL AMOUNT PAID |
| VAN ANDEL INSTITUTE | ||
| E | 48620000 | TOTAL RECORDED |
| VAN ANDEL INSTITUTE | ||
| M | 297622 | ALLOCATION BASED ON SQ. FOOTAGE |
| VAN ANDEL INSTITUTE | ||
| O | 189048 | ACTUAL AMOUNT PAID |
| VAN ANDEL EDUCATION INSTITUTE | ||
| O | 61273 | ACTUAL AMOUNT PAID |
| VAN ANDEL EDUCATION INSTITUTE | ||
| P | 296896 | ACTUAL AMOUNT RECEIVED |
| VAN ANDEL EDUCATION INSTITUTE | ||
| N | 63099 | APPORTIONED SALARY AND BENEFITS |
| VAN ANDEL INSTITUTE GRADUATE SCHOOL | ||
| M | 178573 | ALLOCATION BASED ON SQ. FOOTAGE |
| VAN ANDEL INSTITUTE GRADUATE SCHOOL | ||
| P | 139244 | ACTUAL AMOUNT RECEIVED |
| THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE | ||
| Q | 10928790 | ACTUAL AMOUNT PAID |
| THE TRANSLATIONAL GENOMIC RESEARCH INSTITUTE | ||
| N | 465845 | NET AMOUNT INVOICED |
| THE TRANSLATIONAL GENOMIC RESEARCH INSTITUTE | ||
| C | 1578641 | ACTUAL GRANT TOTAL |
| THE TRANSLATIONAL GENOMIC RESEARCH INSTITUTE | ||
| K | 452155 | ACTUAL AMOUNT PAID |
| THE TRANSLATIONAL GENOMIC RESEARCH INSTITUTE | ||
| B | 36865 | ACCRUED PER CONTRACT |
| THE TRANSLATIONAL GENOMIC RESEARCH INSTITUTE | ||
| O | 17472 | ACTUAL AMOUNT PAID |
| THE TRANSLATIONAL GENOMIC RESEARCH INSTITUTE | ||
| F | 9000 | ACTUAL AMOUNT RECEIVED |
| TRANSMED SYSTEMS INC | ||
| A | 374185 | ACCRUED PER CONTRACT |
| TRANSMED SYSTEMS INC | ||
| B | 500000 | ACTUAL AMOUNT PAID |
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