NATIONAL TUBEROUS SCLEROSIS ASSOCIATION INC: Form 990, tax year 2016

View the entire original 990 at ProPublica ↗

Organization: NATIONAL TUBEROUS SCLEROSIS ASSOCIATION INC (EIN 95-3018799)
Tax period: 2016-01-01 to 2016-12-31
Filed: 2017-04-17
IRS object ID: 201711079349300606
Schema version: 2016v3.0
Source: Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header
Form 990
Schedule A
Schedule B
Schedule C
Schedule D
Schedule F
Schedule G
Schedule I
Schedule J
Schedule O
Schedule R

Return header ReturnHeader

Field	Value	IRS element (for citing)
Return	2017-04-17T08:47:57-05:00	ReturnTs
Tax Period End	2016-12-31	TaxPeriodEndDt

Preparer Firm PreparerFirmGrp

Preparer Firm Name PreparerFirmName

Field	Value	IRS element (for citing)
Business Name Line1	BOND BEEBE PC	BusinessNameLine1Txt

Preparer US Address PreparerUSAddress

Field	Value	IRS element (for citing)
Address Line1	4600 EAST-WEST HIGHWAY SUITE 900	AddressLine1Txt
City	BETHESDA	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	208143423	ZIPCd

Field	Value	IRS element (for citing)
Return Type	990	ReturnTypeCd
Tax Period Begin	2016-01-01	TaxPeriodBeginDt

Filer Filer

Field	Value	IRS element (for citing)
EIN	953018799	EIN

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	NATIONAL TUBEROUS SCLEROSIS ASSOCIATION	BusinessNameLine1Txt
Business Name Line2	INC	BusinessNameLine2Txt

Field	Value	IRS element (for citing)
In Care Of	% THE ORGANIZATION	InCareOfNm
Business Name Control	NATI	BusinessNameControlTxt
Phone	3015629890	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	801 ROEDER ROAD Suite 750	AddressLine1Txt
City	SILVER SPRING	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20910	ZIPCd

Business Officer BusinessOfficerGrp

Field	Value	IRS element (for citing)
Person	KARI L ROSBECK	PersonNm
Person Title	PRESIDENT AND CEO	PersonTitleTxt
Phone	3015629890	PhoneNum
Signature	2017-04-07	SignatureDt
Discuss With Paid Preparer	Yes (true)	DiscussWithPaidPreparerInd

Preparer Person PreparerPersonGrp

Field	Value	IRS element (for citing)
Preparer Person	LAWRENCE J HOFFMAN	PreparerPersonNm
PTIN	P00167087	PTIN
Phone	3012726000	PhoneNum

Filing Security Information FilingSecurityInformation

IP Address IPAddress

Field	Value	IRS element (for citing)
I Pv4 Address	66.195.210.98	IPv4AddressTxt

Field	Value	IRS element (for citing)
Federal Original Submission Id	52746520171075000021	FederalOriginalSubmissionId
Federal Original Submission Id	2017-04-17	FederalOriginalSubmissionIdDt
Filing License Type	P	FilingLicenseTypeCd
At Submission Creation Device Id	483B3F99E9CD71719F6CCAA667530D61A598C20D	AtSubmissionCreationDeviceId
At Submission Filing Device Id	483B3F99E9CD71719F6CCAA667530D61A598C20D	AtSubmissionFilingDeviceId

Field	Value	IRS element (for citing)
Tax	2016	TaxYr
Build TS	2021-01-29 14:40:06Z	BuildTS

Form 990 IRS990

Doing Business As Name DoingBusinessAsName

Field	Value	IRS element (for citing)
Business Name Line1	TUBEROUS SCLEROSIS ALLIANCE	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Principal Officer	KARI L ROSBECK	PrincipalOfficerNm

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	801 ROEDER ROAD STE 750	AddressLine1Txt
City	SILVER SPRING	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20910	ZIPCd

Field	Value	IRS element (for citing)
Gross Receipts	$5,334,129	GrossReceiptsAmt
Group Return For Affiliates	false	GroupReturnForAffiliatesInd
Organization501c3	Yes (X)	Organization501c3Ind
Website Address	WWW.TSALLIANCE.ORG	WebsiteAddressTxt
Type Of Organization Corp	Yes (X)	TypeOfOrganizationCorpInd
Formation	1975	FormationYr
Legal Domicile State	CA	LegalDomicileStateCd
Activity Or Mission	THE TS ALLIANCE IS DEDICATED TO FINDING A CURE FOR TUBEROUS SCLEROSIS COMPLEX WHILE IMPROVING THE LIVES OF THOSE AFFECTED.	ActivityOrMissionDesc
Voting Members Governing Body	19	VotingMembersGoverningBodyCnt
Voting Members Independent	19	VotingMembersIndependentCnt
Total Employee	17	TotalEmployeeCnt
Total Volunteers	1566	TotalVolunteersCnt
Total Gross UBI	$0	TotalGrossUBIAmt
PY Contributions Grants	$3,514,873	PYContributionsGrantsAmt
CY Contributions Grants	$4,517,826	CYContributionsGrantsAmt
PY Program Service Revenue	$478,813	PYProgramServiceRevenueAmt
CY Program Service Revenue	$629,254	CYProgramServiceRevenueAmt
PY Investment Income	$13,679	PYInvestmentIncomeAmt
CY Investment Income	$13,638	CYInvestmentIncomeAmt
PY Other Revenue	$1,071	PYOtherRevenueAmt
CY Other Revenue	$46,841	CYOtherRevenueAmt
PY Total Revenue	$4,008,436	PYTotalRevenueAmt
CY Total Revenue	$5,207,559	CYTotalRevenueAmt
PY Grants And Similar Paid	$488,698	PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid	$940,040	CYGrantsAndSimilarPaidAmt
PY Benefits Paid To Members	$0	PYBenefitsPaidToMembersAmt
CY Benefits Paid To Members	$0	CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid	$1,544,461	PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid	$1,650,060	CYSalariesCompEmpBnftPaidAmt
PY Total Prof Fndrsng Expns	$0	PYTotalProfFndrsngExpnsAmt
CY Total Prof Fndrsng Expns	$0	CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense	$635,871	CYTotalFundraisingExpenseAmt
PY Other Expenses	$1,877,431	PYOtherExpensesAmt
CY Other Expenses	$2,302,337	CYOtherExpensesAmt
PY Total Expenses	$3,910,590	PYTotalExpensesAmt
CY Total Expenses	$4,892,437	CYTotalExpensesAmt
PY Revenues Less Expenses	$97,846	PYRevenuesLessExpensesAmt
CY Revenues Less Expenses	$315,122	CYRevenuesLessExpensesAmt
Total Assets BOY	$8,707,847	TotalAssetsBOYAmt
Total Assets EOY	$10,004,341	TotalAssetsEOYAmt
Total Liabilities BOY	$287,236	TotalLiabilitiesBOYAmt
Total Liabilities EOY	$738,137	TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY	$8,420,611	NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY	$9,266,204	NetAssetsOrFundBalancesEOYAmt
Info In Schedule O Part III	Yes (X)	InfoInScheduleOPartIIIInd
Mission	THE NATIONAL TUBEROUS SCLEROSIS ASSOCIATION, D/B/A TUBEROUS SCLEROSIS ALLIANCE, IS DEDICATED TO FINDING A CURE FOR TUBEROUS SCLEROSIS COMPLEX WHILE IMPROVING THE LIVES OF THOSE AFFECTED.	MissionDesc
Significant New Program Srvc	false	SignificantNewProgramSrvcInd
Significant Change	false	SignificantChangeInd
Expense	$2,469,977	ExpenseAmt
Grant	$887,095	GrantAmt
Revenue	$599,604	RevenueAmt
Desc	Research Program stimulates and supports basic, translational, and clinical research on the various manifestations of tuberous sclerosis complex (TSC) to further the development of clinical therapies and, ultimately, a cure for TSC. The TS Alliance has funded more than $19.7 million in research on TSC since 1984. Directed by Steven L. Roberds, Ph.D., Chief Scientific Officer, the TS Alliance research grants program funds research focused on TSC proposed by researchers and aligned with the research priorities of the TS Alliance. Collaborations between basic and clinical researchers are encouraged and fostered, for example, by biennial International TSC Research Conferences. Through the TS Alliance research grants program, applications can be submitted for postdoctoral fellowships and research grants. Grants are reviewed in a three-step process: (1) all grant applications are reviewed by a committee comprised of scientists knowledgeable about the topic area for scientific merit and of adults affected by TSC for potential impact on the lives of those affected by TSC, (2) the Science and Medical Committee of the Board of Directors evaluates the grant review committees recommendations and the relevance of the applications to the TS Alliances funding priorities, and (3) the Board of Directors then reviews the recommendations of the Science and Medical Committee and makes final approval for funding. Implemented in 2006, the TSC Natural History Database captures clinical data to document the impact of the disease on a persons health over their lifetime. As of December 2016, 2,070 people with tuberous sclerosis complex were enrolled in the project from among 18 U.S.-based sites. The TS Alliance provides funding to participating clinics to perform data entry, monitors the integrity of the database, and makes data available to investigators to answer specific research questions and identify potential participants for clinical trials and studies. In 2016, the TS Alliance invested $431,054 in the TSC Natural History Database and implemented sub-projects on renal angiomyolipomas and subepyndymal giant cell astrocytomas to address detailed questions about these life-threatening manifestations of TSC. A contract with Novartis executed in November 2012 was extended to provide TS Alliance with funding to enhance and grow the depth of data in the TSC Natural History Database through 2018. A total of 15 research awards were funded during 2016 for $887,095. The TS Alliance continued to support eight research grants awarded in previous years. Additionally, seven new research awards were funded beginning in 2016 to (1) Dr. Heng-Jia Liu (Brigham and Womens Hospital) for a postdoctoral fellowship to study T-cell dysfunction in TSC, (2) Dr. Peter Davis (Boston Childrens Hospital) to study brain network biomarkers of epilepsy in TSC, (3) Dr. Jonathan Lipton (Boston Childrens Hospital) to study the circadian clock as a capacitor for TSC-related phenotypes, (4) Dr. Mark Nellist (Erasmus Universitair Medisch Centrum Rotterdam) to functionally characterize TSC1 and TSC2 variants associated with TSC, (5) Dr. Carmen Priolo (Brigham and Womens Hospital) to study the lysophosphatidic acid pathway in TSC, (6) Dr. Peter Tsai (University of Texas Southwestern Medical Center) to study the impact of cerebellar-medial prefrontal cortical circuits in TSC, and (7) Dr. Darcy Krueger (Cincinnati Childrens Hospital Medical Center) to develop a clinical protocol to test the ability of mTOR inhibitors to prevent manifestiations of TSC. With the eight ongoing grants, the TS Alliance continued supporting (1) Dr. Brendan Manning (Harvard School of Public Health) to study the repurposing of inhibitors of purine synthesis for TSC treatment, (2) Dr. Polina Kosillo (University of California, Berkeley) for a postdoctoral fellowship to study the impact of TSC1 gene deletion on dopamine neurons, (3) Dr. Mustafa Sahin (Boston Children's Hospital) to study the "hedgehog" gene and ciliary signaling in TSC, (4) Dr. Sue Povey (University College London) to curate additional mutations in TSC1 and TSC2 genes and make them openly available to the public in a database that is highly utilized by genetic researchers in TSC, (5) Dr. Wei Shi (Childrens Hospital, Los Angeles) to develop and test a novel mouse model of LAM, (6) Dr. Gerta Hoxhaj (Harvard School of Public Health) to study the role of the protein TBC1D7 in cell migration in neurons and angiomyolipomas, (7) Dr. Michael Higley (Yale University) to learn how loss of TSC1 disrupts brain signaling circuits in mice, and (8) Dr. Mustafa Sahin (Boston Childrens Hospital) for supplemental support of imaging analysis in the Rare Diseases Clinical Research Network. The TSC Biosample Repository is a TS Alliance-directed project initiated in 2014 that will impact research over the next ten years or more. High-quality biosamples such as blood, DNA, and tissues linked to detailed clinical data are required for researchers to understand why TSC is so different from person to person. Such samples are currently unavailable, and the TS Alliances Science and Medical Committee identified this as a gap that can only be filled effectively with leadership of the TS Alliance, guided by a steering committee of clinicians and researchers. Samples in the repository are linked to detailed clinical data in our existing TSC Natural History Database and are available to qualified researchers worldwide. Samples are housed at and distributed from the Van Andel Institute in Grand Rapids, Michigan, under control of the TS Alliance. The TSC Biosample Repository has collected 176 blood samples from voluntary participants enrolled in the TSC Natural History Database at Texas Scottish Rite Hospital, Nicklaus Childrens Hospital in Miami, and Minnesota Epilepsy Group, and from RDCRN participants at Boston Childrens Hospital, Cincinnati Childrens Hospital, the University of Alabama at Birmingham, University of Texas Health Science Center at Houston, and UCLA. The TS Alliance launched a new TSC Preclinical Consortium in 2015, which will enable prioritization of candidate treatments based on comparing head-to-head data using consistent animal models and rigorous testing procedures. The TS Alliance is ideally positioned to drive this collaboration - with input from academic, regulatory, and industry stakeholders - by maintaining constant focus on the needs of people with TSC. To drive this project, the TS Alliance contracted with Dr. Daniela Brunner, who has more than 20 years of experience validating in vivo experimental protocols and testing drugs in many animal models of developmental, psychiatric, and neurodegenerative diseases. The TS Alliance has licenses to use specific TSC mouse models for experiments carried out by the Preclinical Consortium, and all mouse license agreements include the rights for the TS Alliance to perform experiments under contract for commercial entities. This ensures that data generated by the Preclinical Consortium can be used to accelerate the development of new treatments by commercial entities as well as academic investigators. Three pharmaceutical companies joined the Preclinical Consortium in 2016. Additionally, four other companies have expressed serious interest. The consortium began running epilepsy experiments in August 2016 at a contract research organization, PsychoGenics, Inc. The TS Alliance continued to be a key part of the TSC Clinical Research Consortium although only a small amount of TS Alliance financial support was required because of the consortiums success in obtaining NATIONAL INSTITUTES OF HEALTH (NIH) funding. Now consisting of seven sites - Boston Childrens Hospital, Cincinnati Childrens Hospital, the University of Alabama at Birmingham, the University of Texas Health Science Center at Houston, UCLA, Stanford University, and Minnesota Epilepsy Group - the consortium has received $29 million in competitive grant funding from the NIH to support clinical studies in TSC. The Clinical Research Consortium is making history with the PREVeNT trial - Preventing epilepsy using vigabatrin in infants with tuberous sclerosis complex. PREVeNT is the first preventative trial for any form of epilepsy in the US and began enrolling participants in December 2016. The PREVeNT trial builds directly upon the Consortiums first clinical study from which interim results have been published (www.ncbi.nlm.nih.gov/pubmed/26498039) showing that all infants who developed abnormal activity on EEGs went on to develop seizures. This trial will determine whether treatment with vigabatrin prior to the onset of clinical seizures in TSC is beneficial to childrens developmental and neurologic outcomes. The TS Alliances Chief Scientific Officer is on the consortiums leadership team.	Desc

Prog Srvc Accom Acty2 ProgSrvcAccomActy2Grp

Field	Value	IRS element (for citing)
Expense	$780,145	ExpenseAmt
Grant	$52,945	GrantAmt
Revenue	$10,250	RevenueAmt
Desc	Family Services develops programs and services that provide individuals with TSC direct access to information, resources, and specialists experienced in the diagnosis, treatment and management of TSC. The Family Services Department provided support and resources to 3,307 individuals and families dealing with TSC throughout 2016. The Vice President of Outreach attended 65 school meetings (IEPs, Evaluation Team Meetings, 504 Plan Meetings, Resolution Meetings, and Mediations) in person, through SKYPE or Facetime, and via conference calls to support families in attaining educational services for their children throughout the country. In 2016, 24 Educational Liaison volunteers worked in 24 states to connect families to free educational advocacy trainings in collaboration with the states Parent Training and Information Centers. As a result, more than 2,344 free parent trainings/webinars on educational advocacy were offered to families dealing with educational issues for their children. In addition, the Educator Mentor Program supported 89 school systems in understanding the learning needs of children with TSC. Through a network of 37 volunteer branches of the organization, called Community Alliances, local education and support group meetings were held throughout the country. Through these Community Alliances, the TS Alliance hosted 76 educational meetings and gatherings. Among these 76 meetings was a 13-meeting Town Hall educational series. The series highlighted transition services offered by The Arc. These Town Hall meetings were hosted in TSC clinics and other venues across the United States with 160 people attending. One new Community Alliance, the TS Alliance of Kentucky/West Virginia, was added in 2016. The TS Alliance facilitated 13,540 peer-to-peer supports from Adult Regional Coordinators, Clinic Ambassadors and Dependent Adult Transition Resource Coordinators and through Community Alliance meetings. In 2016, the TS Alliance hosted three Regional TSC Conferences in partnership with The LAM Foundation held in Nashville, TN; Seattle, WA; and Cleveland, OH with 247 combined attendees. These conferences brought together individuals, parents, caregivers and members of the medical community to provide the most up-to-date information so parents and adults with TSC and LAM can make informed decisions when evaluating treatment options. These one-day symposiums offered educational outreach, information on the latest treatments in TSC and LAM, research updates, and support options. They featured the regions top experts and in a nurturing, supportive environment. Regional TSC Conferences provide much-needed forums for the growing number of people facing the daily challenges of TSC and LAM. To address unmet needs within the global TSC Community, the TS Global Alliance program was launched in 2014 with the TS Alliance of Israel. The program provides the opportunity for the TS Alliance to share experiences and assist in the start-up of support of TSC-related organizations in other countries. A Global Alliance is a structured group of empowered and caring volunteers who work closely with the TS Alliance to facilitate local connections for individuals and families affected by TSC, and raise revenue and awareness while supporting the mission of the organization. In 2016, the TS Alliance signed global agreements with TS Canada ST, TS Alliance of Mexico and the TS Alliance ASEAN Foundation and issued grants of $52,945 to global alliance partners.	Desc

Prog Srvc Accom Acty3 ProgSrvcAccomActy3Grp

Field	Value	IRS element (for citing)
Expense	$293,296	ExpenseAmt
Revenue	$1,500	RevenueAmt
Desc	Public Health Education heightens awareness of TSC throughout the general public to broaden the scope of support and understanding beyond TSC individuals and their families. During 2016, the TS Alliance produced three issues of its national magazine, Perspective, which is mailed to 15,000-plus constituents as well as posted on the website. The TS Alliances website increases awareness and provides extensive education through an average of more than 40,000 unique visitors each month; the site was completely redesigned in 2016 and launched December 14. The TS Alliance also relies heavily on social media to educate constituents and promote new resources and events. Its Facebook Group boasts more than 7,800 members, while its Twitter account has 1,600-plus followers. To increase public awareness, the TS Alliance once again participated in TSC Global Awareness Day on May 15 as well as TSC Awareness Month thoughout May; a TSC Global Awareness Day news release garnered 13.6 million impressions. The TS Alliance again heavily promoted Infantile Spasms Awareness Week with 16 partner organizations, December 1 to 7. This awareness campaign included social media, advertising to first line physicians and parents, and a media tour. Facebook advertising to reach misdiagnosed or those seeking a diagnosis reached 272,936 people. Advertising to first line physicians included an American College of Emergency Physicians newsletter ad with 37,249 subscribers and an American Academy of Pediatrics News ad reaching 64,805 readers. The satellite media tour with 33 aired interviews (21 TV/12 radio) reached a total audience of 6.1 million (309,712 broadcast 5,801,947 radio).	Desc

Field	Value	IRS element (for citing)
Total Other Prog Srvc Expense	$211,911	TotalOtherProgSrvcExpenseAmt
Total Other Prog Srvc Revenue	$17,900	TotalOtherProgSrvcRevenueAmt
Total Program Service Expenses	$3,755,329	TotalProgramServiceExpensesAmt
Described In Section501c3	Yes (true)	DescribedInSection501c3Ind
Schedule B Required	Yes (true)	ScheduleBRequiredInd
Political Campaign Acty	false	PoliticalCampaignActyInd
Lobbying Activities	Yes (true)	LobbyingActivitiesInd
Subject To Proxy Tax	false	SubjectToProxyTaxInd
Donor Advised Fund	false	DonorAdvisedFundInd
Conservation Easements	false	ConservationEasementsInd
Collections Of Art	false	CollectionsOfArtInd
Credit Counseling	false	CreditCounselingInd
Temp Or Permanent Endowments	Yes (true)	TempOrPermanentEndowmentsInd
Report Land Building Equipment	Yes (true)	ReportLandBuildingEquipmentInd
Report Investments Other Sec	false	ReportInvestmentsOtherSecInd
Report Program Related Invst	false	ReportProgramRelatedInvstInd
Report Other Assets	Yes (true)	ReportOtherAssetsInd
Report Other Liabilities	Yes (true)	ReportOtherLiabilitiesInd
Include FIN48 Footnote	Yes (true)	IncludeFIN48FootnoteInd
Independent Audit Fincl Stmt	false	IndependentAuditFinclStmtInd
Consolidated Audit Fincl Stmt	Yes (true)	ConsolidatedAuditFinclStmtInd
School Operating	false	SchoolOperatingInd
Foreign Office	false	ForeignOfficeInd
Foreign Activities	Yes (true)	ForeignActivitiesInd
More Than5000 K To Org	Yes (true)	MoreThan5000KToOrgInd
More Than5000 K To Individuals	false	MoreThan5000KToIndividualsInd
Professional Fundraising	false	ProfessionalFundraisingInd
Fundraising Activities	Yes (true)	FundraisingActivitiesInd
Gaming Activities	false	GamingActivitiesInd
Operate Hospital	false	OperateHospitalInd
Grants To Organizations	Yes (true)	GrantsToOrganizationsInd
Grants To Individuals	false	GrantsToIndividualsInd
Schedule J Required	Yes (true)	ScheduleJRequiredInd
Tax Exempt Bonds	false	TaxExemptBondsInd
Engaged In Excess Benefit Trans	false	EngagedInExcessBenefitTransInd
PY Excess Benefit Trans	false	PYExcessBenefitTransInd
Loan Outstanding	false	LoanOutstandingInd
Grant To Related Person	false	GrantToRelatedPersonInd
Business Rln With Org Mem	false	BusinessRlnWithOrgMemInd
Business Rln With Fam Mem	false	BusinessRlnWithFamMemInd
Business Rln With Officer Ent	false	BusinessRlnWithOfficerEntInd
Deductible Non Cash Contri	false	DeductibleNonCashContriInd
Deductible Art Contribution	false	DeductibleArtContributionInd
Terminate Operations	false	TerminateOperationsInd
Partial Liquidation	false	PartialLiquidationInd
Disregarded Entity	false	DisregardedEntityInd
Related Entity	Yes (true)	RelatedEntityInd
Related Organization Ctrl Ent	false	RelatedOrganizationCtrlEntInd
Activities Conducted Prtshp	false	ActivitiesConductedPrtshpInd
Schedule O Required	Yes (true)	ScheduleORequiredInd
IRP Document	35	IRPDocumentCnt
IRP Document W2 G	0	IRPDocumentW2GCnt
Backup Wthld Compliance	Yes (true)	BackupWthldComplianceInd
Employee	17	EmployeeCnt
Employment Tax Returns Filed	Yes (true)	EmploymentTaxReturnsFiledInd
Unrelated Bus Incm Over Limit	false	UnrelatedBusIncmOverLimitInd
Foreign Financial Account	false	ForeignFinancialAccountInd
Prohibited Tax Shelter Trans	false	ProhibitedTaxShelterTransInd
Taxable Party Notification	false	TaxablePartyNotificationInd
Nondeductible Contributions	false	NondeductibleContributionsInd
Quid Pro Quo Contributions	Yes (true)	QuidProQuoContributionsInd
Quid Pro Quo Contri Discl	Yes (true)	QuidProQuoContriDisclInd
Form8282 Property Disposed Of	false	Form8282PropertyDisposedOfInd
Rcv Fnds To Pay Prsnl Bnft Cntrct	false	RcvFndsToPayPrsnlBnftCntrctInd
Pay Premiums Prsnl Bnft Cntrct	false	PayPremiumsPrsnlBnftCntrctInd
Indoor Tanning Services	false	IndoorTanningServicesInd
Info In Schedule O Part VI	Yes (X)	InfoInScheduleOPartVIInd
Governing Body Voting Members	19	GoverningBodyVotingMembersCnt
Independent Voting Member	19	IndependentVotingMemberCnt
Family Or Business Rln	false	FamilyOrBusinessRlnInd
Delegation Of Mgmt Duties	false	DelegationOfMgmtDutiesInd
Change To Org Documents	false	ChangeToOrgDocumentsInd
Material Diversion Or Misuse	false	MaterialDiversionOrMisuseInd
Members Or Stockholders	Yes (true)	MembersOrStockholdersInd
Election Of Board Members	Yes (true)	ElectionOfBoardMembersInd
Decisions Subject To Approva	false	DecisionsSubjectToApprovaInd
Minutes Of Governing Body	Yes (true)	MinutesOfGoverningBodyInd
Minutes Of Committees	Yes (true)	MinutesOfCommitteesInd
Officer Mailing Address	false	OfficerMailingAddressInd
Local Chapters	Yes (true)	LocalChaptersInd
Policies Reference Chapters	Yes (true)	PoliciesReferenceChaptersInd
Form990 Provided To Gvrn Body	Yes (true)	Form990ProvidedToGvrnBodyInd
Conflict Of Interest Policy	Yes (true)	ConflictOfInterestPolicyInd
Annual Disclosure Covered Prsn	Yes (true)	AnnualDisclosureCoveredPrsnInd
Regular Monitoring Enfrc	Yes (true)	RegularMonitoringEnfrcInd
Whistleblower Policy	Yes (true)	WhistleblowerPolicyInd
Document Retention Policy	Yes (true)	DocumentRetentionPolicyInd
Compensation Process CEO	Yes (true)	CompensationProcessCEOInd
Compensation Process Other	Yes (true)	CompensationProcessOtherInd
Investment In Joint Venture	false	InvestmentInJointVentureInd
States Where Copy Of Return Is Fld	AL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	AZ	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	AR	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	CA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	CT	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	FL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	GA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	HI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	IL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	IN	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	KS	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	KY	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	ME	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MD	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MN	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MS	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NH	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NJ	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NM	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NY	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NC	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OK	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OR	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	PA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	RI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	SC	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	TN	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	UT	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	VA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	WV	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	WI	StatesWhereCopyOfReturnIsFldCd
Own Website	Yes (X)	OwnWebsiteInd
Other Website	Yes (X)	OtherWebsiteInd
Upon Request	Yes (X)	UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

Field	Value	IRS element (for citing)
Person	THE ORGANIZATION	PersonNm
Phone	3015629890	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	801 ROEDER ROAD STE 750	AddressLine1Txt
City	SILVER SPRING	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20910	ZIPCd

Field	Value	IRS element (for citing)
Info In Schedule O Part VII	Yes (X)	InfoInScheduleOPartVIIInd

Form990 Part VII Section A Form990PartVIISectionAGrp (23 entries)

TitleTitleTxt	Average Hours Per WeekAverageHoursPerWeekRt	Average Hours Per Week Rltd OrgAverageHoursPerWeekRltdOrgRt	Individual Trustee Or DirectorIndividualTrusteeOrDirectorInd	OfficerOfficerInd	Reportable Comp From OrgReportableCompFromOrgAmt	Reportable Comp From Rltd OrgReportableCompFromRltdOrgAmt	Other CompensationOtherCompensationAmt	Key EmployeeKeyEmployeeInd	Highest Compensated EmployeeHighestCompensatedEmployeeInd
DAVID FITZMAURICE
CHAIR	5.0	0.0	Yes (X)	Yes (X)	$0	$0	$0
TIM DILLS
VICE CHAIR	5.0	0.0	Yes (X)	Yes (X)	$0	$0	$0
LAURA S LUBBERS
IMMEDIATE PAST CHAIR	5.0	0.0	Yes (X)	Yes (X)	$0	$0	$0
BETH DEAN
SECRETARY	5.0	0.0	Yes (X)	Yes (X)	$0	$0	$0
DARREN MILES
TREASURER	5.0	0.0	Yes (X)	Yes (X)	$0	$0	$0
REBECCA ANHANG PRICE
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
MARTINA BEBIN MD MPA
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
JOHN J BISSLER MD
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
MICHAEL CAGGIANO
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
CASSANDRA CARROLL
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
APRIL COOPER
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
BONNIE HOGUE DUFFY
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
KEITH A HALL
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
JIM MAGINN
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
BRENDAN D MANNING PHD
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
THEODORE MASTROIANNI
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
DAVID MICHAELS
BOARD MEMBER	2.0	2.0	Yes (X)		$0	$0	$0
DEBORA L MORITZ
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
MATTHEW SIMONIAN
BOARD MEMBER	2.0	0.0	Yes (X)		$0	$0	$0
KARI L ROSEBECK
PRESIDENT & CEO	54.0	1.0		Yes (X)	$170,716	$0	$26,641
RICHARD A GOLLUB
CONTROLLER & CFO	46.5	3.5		Yes (X)	$132,717	$0	$30,661
STEVEN L ROBERDS
CHIEF SCIENTIFIC OFFICER	45.0	0.0			$184,985	$0	$29,172	Yes (X)
JAYE D ISHAM
VP, COMMUNICATIONS STRATEGY	45.0	0.0			$100,926	$0	$3,670		Yes (X)

Field	Value	IRS element (for citing)
Total Reportable Comp From Org	$589,344	TotalReportableCompFromOrgAmt
Tot Reportable Comp Rltd Org	$0	TotReportableCompRltdOrgAmt
Total Other Compensation	$90,144	TotalOtherCompensationAmt
Indiv Rcvd Greater Than100 K	4	IndivRcvdGreaterThan100KCnt
Former Ofcr Employees Listed	false	FormerOfcrEmployeesListedInd
Total Comp Greater Than150 K	Yes (true)	TotalCompGreaterThan150KInd
Compensation From Other Srcs	false	CompensationFromOtherSrcsInd

Contractor Compensation ContractorCompensationGrp

Contractor Name ContractorName

Field	Value	IRS element (for citing)
Person	CAVAROCCHI RUSCIO DENNIS ASSOCIAT	PersonNm

Contractor Address ContractorAddress

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	600 MARYLAND AVE SW STE 835W	AddressLine1Txt
City	WASHINGTON	CityNm
State Abbreviation	DC	StateAbbreviationCd
ZIP	20024	ZIPCd

Field	Value	IRS element (for citing)
Services	GOVT RELATIONS	ServicesDesc
Compensation	$103,884	CompensationAmt

Field	Value	IRS element (for citing)
Cntrct Rcvd Greater Than100 K	1	CntrctRcvdGreaterThan100KCnt
Info In Schedule O Part VIII	Yes (X)	InfoInScheduleOPartVIIIInd
Federated Campaigns	$36,891	FederatedCampaignsAmt
Membership Dues	$9,045	MembershipDuesAmt
Fundraising	$1,284,683	FundraisingAmt
All Other Contributions	$3,187,207	AllOtherContributionsAmt
Noncash Contributions	$19,494	NoncashContributionsAmt
Total Contributions	$4,517,826	TotalContributionsAmt

Program Service Revenue ProgramServiceRevenueGrp

Field	Value	IRS element (for citing)
Desc	CONTRACT REVENUE	Desc
Business	900099	BusinessCd
Total Revenue Column	$629,254	TotalRevenueColumnAmt
Related Or Exempt Func Income	$629,254	RelatedOrExemptFuncIncomeAmt

Field	Value	IRS element (for citing)
Total Program Service Revenue	$629,254	TotalProgramServiceRevenueAmt

Investment Income InvestmentIncomeGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$14,763	TotalRevenueColumnAmt
Exclusion	$14,763	ExclusionAmt

Incm From Invest Bond Proceeds IncmFromInvestBondProceedsGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt

Royalties Revenue RoyaltiesRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$668	TotalRevenueColumnAmt
Exclusion	$668	ExclusionAmt

Rental Income Or Loss RentalIncomeOrLossGrp

Field	Value	IRS element (for citing)
Real	$0	RealAmt
Personal	$0	PersonalAmt

Net Rental Income Or Loss NetRentalIncomeOrLossGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt

Gross Amount Sales Assets GrossAmountSalesAssetsGrp

Field	Value	IRS element (for citing)
Securities	$20,269	SecuritiesAmt

Less Cost Oth Basis Sales Expnss LessCostOthBasisSalesExpnssGrp

Field	Value	IRS element (for citing)
Securities	$19,494	SecuritiesAmt
Other	$1,900	OtherAmt

Gain Or Loss GainOrLossGrp

Field	Value	IRS element (for citing)
Securities	$775	SecuritiesAmt
Other	-$1,900	OtherAmt

Net Gain Or Loss Investments NetGainOrLossInvestmentsGrp

Field	Value	IRS element (for citing)
Total Revenue Column	-$1,125	TotalRevenueColumnAmt
Exclusion	-$1,125	ExclusionAmt

Field	Value	IRS element (for citing)
Fundraising Gross Income	$149,666	FundraisingGrossIncomeAmt
Contri Rpt Fundraising Event	$1,284,683	ContriRptFundraisingEventAmt
Fundraising Direct Expenses	$105,176	FundraisingDirectExpensesAmt

Net Incm From Fundraising Evt NetIncmFromFundraisingEvtGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$44,490	TotalRevenueColumnAmt
Exclusion	$44,490	ExclusionAmt

Net Income From Gaming NetIncomeFromGamingGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt

Net Income Or Loss NetIncomeOrLossGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt

Other Revenue Misc OtherRevenueMiscGrp

Field	Value	IRS element (for citing)
Desc	MISCELLANEOUS	Desc
Business	900099	BusinessCd
Total Revenue Column	$1,683	TotalRevenueColumnAmt
Exclusion	$1,683	ExclusionAmt

Field	Value	IRS element (for citing)
Other Revenue Total	$1,683	OtherRevenueTotalAmt

Total Revenue TotalRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$5,207,559	TotalRevenueColumnAmt
Related Or Exempt Func Income	$629,254	RelatedOrExemptFuncIncomeAmt
Exclusion	$60,479	ExclusionAmt

Grants To Domestic Orgs GrantsToDomesticOrgsGrp

Field	Value	IRS element (for citing)
Total	$748,650	TotalAmt
Program Services	$748,650	ProgramServicesAmt

Grants To Domestic Individuals GrantsToDomesticIndividualsGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Foreign Grants ForeignGrantsGrp

Field	Value	IRS element (for citing)
Total	$191,390	TotalAmt
Program Services	$191,390	ProgramServicesAmt

Benefits To Members BenefitsToMembersGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Comp Current Ofcr Directors CompCurrentOfcrDirectorsGrp

Field	Value	IRS element (for citing)
Total	$580,223	TotalAmt
Program Services	$315,695	ProgramServicesAmt
Management And General	$201,956	ManagementAndGeneralAmt
Fundraising	$62,572	FundraisingAmt

Comp Disqual Persons CompDisqualPersonsGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Other Salaries And Wages OtherSalariesAndWagesGrp

Field	Value	IRS element (for citing)
Total	$863,353	TotalAmt
Program Services	$490,279	ProgramServicesAmt
Management And General	$125,398	ManagementAndGeneralAmt
Fundraising	$247,676	FundraisingAmt

Pension Plan Contributions PensionPlanContributionsGrp

Field	Value	IRS element (for citing)
Total	$27,060	TotalAmt
Program Services	$16,808	ProgramServicesAmt
Management And General	$2,984	ManagementAndGeneralAmt
Fundraising	$7,268	FundraisingAmt

Other Employee Benefits OtherEmployeeBenefitsGrp

Field	Value	IRS element (for citing)
Total	$82,706	TotalAmt
Program Services	$53,411	ProgramServicesAmt
Management And General	$515	ManagementAndGeneralAmt
Fundraising	$28,780	FundraisingAmt

Payroll Taxes PayrollTaxesGrp

Field	Value	IRS element (for citing)
Total	$96,718	TotalAmt
Program Services	$55,027	ProgramServicesAmt
Management And General	$19,893	ManagementAndGeneralAmt
Fundraising	$21,798	FundraisingAmt

Fees For Services Management FeesForServicesManagementGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Fees For Services Legal FeesForServicesLegalGrp

Field	Value	IRS element (for citing)
Total	$51,675	TotalAmt
Program Services	$33,241	ProgramServicesAmt
Management And General	$15,684	ManagementAndGeneralAmt
Fundraising	$2,750	FundraisingAmt

Fees For Services Accounting FeesForServicesAccountingGrp

Field	Value	IRS element (for citing)
Total	$27,915	TotalAmt
Management And General	$27,915	ManagementAndGeneralAmt

Fees For Services Lobbying FeesForServicesLobbyingGrp

Field	Value	IRS element (for citing)
Total	$104,376	TotalAmt
Program Services	$104,376	ProgramServicesAmt

Fees For Services Prof Fundraising FeesForServicesProfFundraising

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Fees For Srvc Invst Mgmnt Fees FeesForSrvcInvstMgmntFeesGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Fees For Services Other FeesForServicesOtherGrp

Field	Value	IRS element (for citing)
Total	$112,001	TotalAmt
Program Services	$71,314	ProgramServicesAmt
Management And General	$7,391	ManagementAndGeneralAmt
Fundraising	$33,296	FundraisingAmt

Advertising AdvertisingGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Office Expenses OfficeExpensesGrp

Field	Value	IRS element (for citing)
Total	$318,858	TotalAmt
Program Services	$136,411	ProgramServicesAmt
Management And General	$77,990	ManagementAndGeneralAmt
Fundraising	$104,457	FundraisingAmt

Information Technology InformationTechnologyGrp

Field	Value	IRS element (for citing)
Total	$118,628	TotalAmt
Program Services	$25,916	ProgramServicesAmt
Management And General	$92,712	ManagementAndGeneralAmt

Royalties RoyaltiesGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Occupancy OccupancyGrp

Field	Value	IRS element (for citing)
Total	$81,757	TotalAmt
Program Services	$270	ProgramServicesAmt
Management And General	$81,217	ManagementAndGeneralAmt
Fundraising	$270	FundraisingAmt

Travel TravelGrp

Field	Value	IRS element (for citing)
Total	$218,353	TotalAmt
Program Services	$169,816	ProgramServicesAmt
Management And General	$2,496	ManagementAndGeneralAmt
Fundraising	$46,041	FundraisingAmt

Pymt Travel Entrtnmnt Pub Ofcl PymtTravelEntrtnmntPubOfclGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Conferences Meetings ConferencesMeetingsGrp

Field	Value	IRS element (for citing)
Total	$135,409	TotalAmt
Program Services	$105,535	ProgramServicesAmt
Management And General	$27,503	ManagementAndGeneralAmt
Fundraising	$2,371	FundraisingAmt

Interest InterestGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Payments To Affiliates PaymentsToAffiliatesGrp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Depreciation Depletion DepreciationDepletionGrp

Field	Value	IRS element (for citing)
Total	$50,471	TotalAmt
Program Services	$3,147	ProgramServicesAmt
Management And General	$47,324	ManagementAndGeneralAmt

Insurance InsuranceGrp

Field	Value	IRS element (for citing)
Total	$7,348	TotalAmt
Management And General	$7,348	ManagementAndGeneralAmt

Other Expenses OtherExpensesGrp (4 entries)

DescDesc	TotalTotalAmt	Program ServicesProgramServicesAmt	Management And GeneralManagementAndGeneralAmt	FundraisingFundraisingAmt
PRECLINICAL CONSORTIUM	$492,760	$492,760
NATURAL HISTORY DATABASE	$431,054	$431,054
BIOSAMPLE REPOSITORY	$82,925	$82,925
OVERHEAD ALLOCATION		$188,625	-$262,909	$74,284

All Other Expenses AllOtherExpensesGrp

Field	Value	IRS element (for citing)
Total	$68,807	TotalAmt
Program Services	$38,679	ProgramServicesAmt
Management And General	$25,820	ManagementAndGeneralAmt
Fundraising	$4,308	FundraisingAmt

Total Functional Expenses TotalFunctionalExpensesGrp

Field	Value	IRS element (for citing)
Total	$4,892,437	TotalAmt
Program Services	$3,755,329	ProgramServicesAmt
Management And General	$501,237	ManagementAndGeneralAmt
Fundraising	$635,871	FundraisingAmt

Field	Value	IRS element (for citing)
Joint Costs	Yes (X)	JointCostsInd

Total Joint Costs TotalJointCostsGrp

Field	Value	IRS element (for citing)
Total	$104,180	TotalAmt
Program Services	$52,090	ProgramServicesAmt
Fundraising	$52,090	FundraisingAmt

Cash Non Interest Bearing CashNonInterestBearingGrp

Field	Value	IRS element (for citing)
BOY	$2,873,836	BOYAmt
EOY	$1,840,325	EOYAmt

Savings And Temp Cash Invst SavingsAndTempCashInvstGrp

Field	Value	IRS element (for citing)
BOY	$499,163	BOYAmt
EOY	$779,808	EOYAmt

Pledges And Grants Receivable PledgesAndGrantsReceivableGrp

Field	Value	IRS element (for citing)
BOY	$316,197	BOYAmt
EOY	$1,480,988	EOYAmt

Accounts Receivable AccountsReceivableGrp

Field	Value	IRS element (for citing)
BOY	$2,450	BOYAmt
EOY	$262,025	EOYAmt

Receivables From Officers Etc ReceivablesFromOfficersEtcGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Rcvbl From Disqualified Prsn RcvblFromDisqualifiedPrsnGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Oth Notes Loans Receivable Net OthNotesLoansReceivableNetGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Inventories For Sale Or Use InventoriesForSaleOrUseGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Prepaid Expenses Defrd Charges PrepaidExpensesDefrdChargesGrp

Field	Value	IRS element (for citing)
BOY	$107,800	BOYAmt
EOY	$182,942	EOYAmt

Field	Value	IRS element (for citing)
Land Bldg Equip Cost Or Other Bss	$360,151	LandBldgEquipCostOrOtherBssAmt
Land Bldg Equip Accum Deprec	$169,819	LandBldgEquipAccumDeprecAmt

Land Bldg Equip Basis Net LandBldgEquipBasisNetGrp

Field	Value	IRS element (for citing)
BOY	$146,437	BOYAmt
EOY	$190,332	EOYAmt

Investments Pub Traded Sec InvestmentsPubTradedSecGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Investments Other Securities InvestmentsOtherSecuritiesGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Investments Program Related InvestmentsProgramRelatedGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Intangible Assets IntangibleAssetsGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Other Assets Total OtherAssetsTotalGrp

Field	Value	IRS element (for citing)
BOY	$4,761,964	BOYAmt
EOY	$5,267,921	EOYAmt

Total Assets TotalAssetsGrp

Field	Value	IRS element (for citing)
BOY	$8,707,847	BOYAmt
EOY	$10,004,341	EOYAmt

Accounts Payable Accr Expnss AccountsPayableAccrExpnssGrp

Field	Value	IRS element (for citing)
BOY	$270,808	BOYAmt
EOY	$523,259	EOYAmt

Grants Payable GrantsPayableGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Deferred Revenue DeferredRevenueGrp

Field	Value	IRS element (for citing)
BOY	$16,428	BOYAmt
EOY	$131,976	EOYAmt

Tax Exempt Bond Liabilities TaxExemptBondLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Escrow Account Liability EscrowAccountLiabilityGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Loans From Officers Directors LoansFromOfficersDirectorsGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Mortg Notes Pybl Scrd Invst Prop MortgNotesPyblScrdInvstPropGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Unsecured Notes Loans Payable UnsecuredNotesLoansPayableGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Other Liabilities OtherLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$82,902	EOYAmt

Total Liabilities TotalLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$287,236	BOYAmt
EOY	$738,137	EOYAmt

Field	Value	IRS element (for citing)
Organization Follows SFAS117	Yes (X)	OrganizationFollowsSFAS117Ind

Unrestricted Net Assets UnrestrictedNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$5,643,768	BOYAmt
EOY	$5,303,111	EOYAmt

Temporarily Rstr Net Assets TemporarilyRstrNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$1,897,399	BOYAmt
EOY	$3,083,649	EOYAmt

Permanently Rstr Net Assets PermanentlyRstrNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$879,444	BOYAmt
EOY	$879,444	EOYAmt

Total Net Assets Fund Balance TotalNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$8,420,611	BOYAmt
EOY	$9,266,204	EOYAmt

Tot Liab Net Assets Fund Balance TotLiabNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$8,707,847	BOYAmt
EOY	$10,004,341	EOYAmt

Field	Value	IRS element (for citing)
Info In Schedule O Part XI	Yes (X)	InfoInScheduleOPartXIInd
Reconcilation Revenue Expnss	$315,122	ReconcilationRevenueExpnssAmt
Other Changes In Net Assets	$530,471	OtherChangesInNetAssetsAmt
Info In Schedule O Part XII	Yes (X)	InfoInScheduleOPartXIIInd
Method Of Accounting Accrual	Yes (X)	MethodOfAccountingAccrualInd
Accountant Compile Or Review	false	AccountantCompileOrReviewInd
FS Audited	Yes (true)	FSAuditedInd

FS Audited Basis FSAuditedBasisGrp

Field	Value	IRS element (for citing)
Consolidated Basis Fincl Stmt	Yes (X)	ConsolidatedBasisFinclStmtInd

Field	Value	IRS element (for citing)
Audit Committee	Yes (true)	AuditCommitteeInd
Federal Grant Audit Required	false	FederalGrantAuditRequiredInd

Schedule A IRS990ScheduleA

Field	Value	IRS element (for citing)
Public Organization170	Yes (X)	PublicOrganization170Ind

Gifts Grants Contri Rcvd170 GiftsGrantsContriRcvd170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$3,199,643	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$3,239,048	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$3,124,386	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$3,514,873	CurrentTaxYearMinus1YearAmt
Current Tax Year	$4,517,826	CurrentTaxYearAmt
Total	$17,595,776	TotalAmt

Tax Rev Levied Orgnztnl Bnft170 TaxRevLeviedOrgnztnlBnft170Grp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Govt Furn Srvc Fclts Vl170 GovtFurnSrvcFcltsVl170Grp

Field	Value	IRS element (for citing)
Total	$0	TotalAmt

Total Calendar Year170 TotalCalendarYear170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$3,199,643	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$3,239,048	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$3,124,386	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$3,514,873	CurrentTaxYearMinus1YearAmt
Current Tax Year	$4,517,826	CurrentTaxYearAmt
Total	$17,595,776	TotalAmt

Field	Value	IRS element (for citing)
Substantial Contributors Tot	$3,168,321	SubstantialContributorsTotAmt
Public Support Total170	$14,427,455	PublicSupportTotal170Amt

Gross Investment Income170 GrossInvestmentIncome170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$9,794	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$13,335	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$13,455	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$16,038	CurrentTaxYearMinus1YearAmt
Current Tax Year	$15,431	CurrentTaxYearAmt
Total	$68,053	TotalAmt

Unrelated Business Net Incm170 UnrelatedBusinessNetIncm170Grp

Field	Value	IRS element (for citing)
Current Tax Year	$44,490	CurrentTaxYearAmt
Total	$44,490	TotalAmt

Other Income170 OtherIncome170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$23,048	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$5,984	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$9,351	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$1,401	CurrentTaxYearMinus1YearAmt
Current Tax Year	$1,683	CurrentTaxYearAmt
Total	$41,467	TotalAmt

Field	Value	IRS element (for citing)
Total Support	$17,749,786	TotalSupportAmt
Gross Receipts Rltd Activities	$3,531,539	GrossReceiptsRltdActivitiesAmt
Public Support CY170	0.81282	PublicSupportCY170Pct
Public Support PY170	0.85040	PublicSupportPY170Pct
Thirty Thr Pct Suprt Tests CY170	Yes (X)	ThirtyThrPctSuprtTestsCY170Ind

Schedule B IRS990ScheduleB

Contributor Information ContributorInformationGrp

Field	Value	IRS element (for citing)
Contributor	RESTRICTED	ContributorNum

Contributor Business Name ContributorBusinessName

Field	Value	IRS element (for citing)
Business Name Line1	RESTRICTED	BusinessNameLine1

Contributor US Address ContributorUSAddress

Field	Value	IRS element (for citing)
Address Line1	RESTRICTED	AddressLine1
Address Line2	RESTRICTED	AddressLine2
City	RESTRICTED	City
State	RESTRICTED	State
ZIP Code	RESTRICTED	ZIPCode

Field	Value	IRS element (for citing)
Total Contributions	RESTRICTED	TotalContributionsAmt

Schedule C IRS990ScheduleC

Total Grassroots Lobbying TotalGrassrootsLobbyingGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$986	FilingOrganizationsTotalAmt

Total Direct Lobbying TotalDirectLobbyingGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$145,927	FilingOrganizationsTotalAmt

Total Lobbying Expend TotalLobbyingExpendGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$146,913	FilingOrganizationsTotalAmt

Other Exempt Purpose Expend OtherExemptPurposeExpendGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$4,745,524	FilingOrganizationsTotalAmt

Total Exempt Purpose Expend TotalExemptPurposeExpendGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$4,892,437	FilingOrganizationsTotalAmt

Lobbying Nontaxable Amount LobbyingNontaxableAmountGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$394,622	FilingOrganizationsTotalAmt

Grassroots Nontaxable GrassrootsNontaxableGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$98,656	FilingOrganizationsTotalAmt

Field	Value	IRS element (for citing)
Tot Lbbyng Grassroot Mns Non Tx		TotLbbyngGrassrootMnsNonTxGrp
Tot Lbby Expend Mns Lbbyng Non Tx		TotLbbyExpendMnsLbbyngNonTxGrp

Avg Lobbying Nontaxable Amount AvgLobbyingNontaxableAmountGrp

Field	Value	IRS element (for citing)
Current Year Minus3	$354,161	CurrentYearMinus3Amt
Current Year Minus2	$362,797	CurrentYearMinus2Amt
Current Year Minus1	$364,719	CurrentYearMinus1Amt
Current Year	$394,622	CurrentYearAmt
Total	$1,476,299	TotalAmt

Field	Value	IRS element (for citing)
Lobbying Ceiling	$2,214,449	LobbyingCeilingAmt

Avg Total Lobbying Expend AvgTotalLobbyingExpendGrp

Field	Value	IRS element (for citing)
Current Year Minus3	$142,520	CurrentYearMinus3Amt
Current Year Minus2	$178,975	CurrentYearMinus2Amt
Current Year Minus1	$126,441	CurrentYearMinus1Amt
Current Year	$145,927	CurrentYearAmt
Total	$593,863	TotalAmt

Avg Grassroots Nontaxable AvgGrassrootsNontaxableGrp

Field	Value	IRS element (for citing)
Current Year Minus3	$88,540	CurrentYearMinus3Amt
Current Year Minus2	$90,699	CurrentYearMinus2Amt
Current Year Minus1	$91,180	CurrentYearMinus1Amt
Current Year	$98,656	CurrentYearAmt
Total	$369,075	TotalAmt

Field	Value	IRS element (for citing)
Grassroots Ceiling	$553,613	GrassrootsCeilingAmt

Avg Grassroots Lobbying Expend AvgGrassrootsLobbyingExpendGrp

Field	Value	IRS element (for citing)
Current Year Minus3	$919	CurrentYearMinus3Amt
Current Year Minus2	$905	CurrentYearMinus2Amt
Current Year Minus1	$5,047	CurrentYearMinus1Amt
Current Year	$986	CurrentYearAmt
Total	$7,857	TotalAmt

Schedule D IRS990ScheduleD

Field	Value	IRS element (for citing)
Art Public Exhibition Amounts		ArtPublicExhibitionAmountsGrp
Held Works Art		HeldWorksArtGrp

CY Endwmt Fund CYEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$4,763,517	BeginningYearBalanceAmt
Contributions	$58,749	ContributionsAmt
Investment Earnings Or Losses	$525,868	InvestmentEarningsOrLossesAmt
Administrative Expenses	$54,145	AdministrativeExpensesAmt
End Year Balance	$5,293,989	EndYearBalanceAmt

CY Minus1 Yr Endwmt Fund CYMinus1YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$5,061,299	BeginningYearBalanceAmt
Contributions	$29,940	ContributionsAmt
Investment Earnings Or Losses	$93,294	InvestmentEarningsOrLossesAmt
Other Expenditures	$202,000	OtherExpendituresAmt
Administrative Expenses	$32,428	AdministrativeExpensesAmt
End Year Balance	$4,950,105	EndYearBalanceAmt

CY Minus2 Yr Endwmt Fund CYMinus2YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$4,994,766	BeginningYearBalanceAmt
Contributions	$47,153	ContributionsAmt
Investment Earnings Or Losses	$179,553	InvestmentEarningsOrLossesAmt
Other Expenditures	$97,500	OtherExpendituresAmt
Administrative Expenses	$62,673	AdministrativeExpensesAmt
End Year Balance	$5,061,299	EndYearBalanceAmt

CY Minus3 Yr Endwmt Fund CYMinus3YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$4,457,365	BeginningYearBalanceAmt
Contributions	$42,690	ContributionsAmt
Investment Earnings Or Losses	$718,381	InvestmentEarningsOrLossesAmt
Other Expenditures	$197,200	OtherExpendituresAmt
Administrative Expenses	$26,470	AdministrativeExpensesAmt
End Year Balance	$4,994,766	EndYearBalanceAmt

CY Minus4 Yr Endwmt Fund CYMinus4YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$4,221,150	BeginningYearBalanceAmt
Contributions	$43,996	ContributionsAmt
Investment Earnings Or Losses	$420,983	InvestmentEarningsOrLossesAmt
Other Expenditures	$202,000	OtherExpendituresAmt
Administrative Expenses	$26,764	AdministrativeExpensesAmt
End Year Balance	$4,457,365	EndYearBalanceAmt

Field	Value	IRS element (for citing)
Board Designated Balance EOY	0.81390	BoardDesignatedBalanceEOYPct
Prmnnt Endowment Balance EOY	0.16610	PrmnntEndowmentBalanceEOYPct
Term Endowment Balance EOY	0.02000	TermEndowmentBalanceEOYPct
Endowments Held Unrelated Org	false	EndowmentsHeldUnrelatedOrgInd
Endowments Held Related Org	Yes (true)	EndowmentsHeldRelatedOrgInd
Related Org List Sch R	Yes (true)	RelatedOrgListSchRInd
Land		LandGrp
Buildings		BuildingsGrp

Leasehold Improvements LeaseholdImprovementsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$156,545	OtherCostOrOtherBasisAmt
Depreciation	$84,224	DepreciationAmt
Book Value	$72,321	BookValueAmt

Equipment EquipmentGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$19,886	OtherCostOrOtherBasisAmt
Depreciation	$8,450	DepreciationAmt
Book Value	$11,436	BookValueAmt

Other Land Buildings OtherLandBuildingsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$183,720	OtherCostOrOtherBasisAmt
Depreciation	$77,145	DepreciationAmt
Book Value	$106,575	BookValueAmt

Field	Value	IRS element (for citing)
Total Book Value Land Buildings	$190,332	TotalBookValueLandBuildingsAmt

Other Assets Org OtherAssetsOrgGrp (2 entries)

DescDesc	Book ValueBookValueAmt
INTEREST IN NET ASSETS OF AFFI	$5,293,962
DUE FROM AFFILIATE	-$26,041

Field	Value	IRS element (for citing)
Total Book Value Other Assets	$5,267,921	TotalBookValueOtherAssetsAmt
Federal Income Tax Liability	$0	FederalIncomeTaxLiabilityAmt

Other Liabilities Org OtherLiabilitiesOrgGrp

Field	Value	IRS element (for citing)
Desc	DEFERRED RENT & LEASE INCENTIVE	Desc
Amt	$82,902	Amt

Field	Value	IRS element (for citing)
Total Liability	$82,902	TotalLiabilityAmt
Footnote Text	Yes (X)	FootnoteTextInd
Total Rev Etc Audited Fincl Stmt	$5,794,361	TotalRevEtcAuditedFinclStmtAmt
Net Unrealized Gains Invst	$161,688	NetUnrealizedGainsInvstAmt
Donated Services And Use Fclts	$26,947	DonatedServicesAndUseFcltsAmt
Other Revenue	$398,167	OtherRevenueAmt
Revenue Not Reported	$586,802	RevenueNotReportedAmt
Revenue Subtotal	$5,207,559	RevenueSubtotalAmt
Total Revenue Per Form990	$5,207,559	TotalRevenuePerForm990Amt
Tot Expns Etc Audited Fincl Stmt	$4,948,768	TotExpnsEtcAuditedFinclStmtAmt
Donated Services Use Fclts	$26,947	DonatedServicesUseFcltsAmt
Other Expenses Included	$29,384	OtherExpensesIncludedAmt
Expenses Not Reported	$56,331	ExpensesNotReportedAmt
Expenses Subtotal	$4,892,437	ExpensesSubtotalAmt
Total Expenses Per Form990	$4,892,437	TotalExpensesPerForm990Amt

Supplemental Information Detail SupplementalInformationDetail (4 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
PART V, LINE 4:	THE ALLIANCE'S ENDOWMENTS CONSIST OF TWO FUNDS ESTABLISHED FOR DIFFERENT PURPOSES. THE ALLIANCE'S ENDOWMENT INCLUDE ONE TRADITIONAL DONOR-RESTRICTED ENDOWMENT FUNDS AND ONE BOARD-DESIGNATED ENDOWMENT FUND. THE BOARD-DESIGNATED ENDOWMENT FUND SOLELY CONSISTS OF THE ENDOWMENT FUND'S UNRESTRICTED NET ASSET BALANCE.
PART X, LINE 2:	Accounting principles generally accepted in the United States of America require management to evaluate income tax positions taken and accrue an income tax liability if the organization has taken an uncertain position that more likely than not would not be sustained upon examination by the Internal Revenue Service. Management has evaluated the income tax positions taken and concluded that as of December 31, 2016 there are no uncertain positions taken or expected to be taken that would require accrual of a liability in the consolidated financial statements. The Alliance is subject to routine audits by taxing jurisdictions; however, there are currently no audits in progress for any tax periods. As of December 31, 2016 the statute of limitations for tax years 2013 through 2015 remains open with the U.S. federal jurisdiction or the various states and local jurisdictions in which the Alliance files tax returns.
PART XI, LINE 2D - OTHER ADJUSTMENTS:	$398,167 REVENUES FROM RELATED ORGANIZATION
PART XII, LINE 2D - OTHER ADJUSTMENTS:	$29,384 EXPENSES FROM RELATED ORGANIZATION

Schedule F IRS990ScheduleF

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (true)	GrantRecordsMaintainedInd

Account Activities Outside US AccountActivitiesOutsideUSGrp (3 entries)

RegionRegionTxt	Type Of Activities ConductedTypeOfActivitiesConductedTxt	Region Total ExpendituresRegionTotalExpendituresAmt
Europe (Including Iceland and Greenland)	Grantmaking	$138,445
North America	Grantmaking	$25,000
East Asia and the Pacific	Grantmaking	$27,945

Field	Value	IRS element (for citing)
Subtotal Spent	$191,390	SubtotalSpentAmt
Total Spent	$191,390	TotalSpentAmt

Grants To Org Outside US GrantsToOrgOutsideUSGrp (4 entries)

RegionRegionTxt	Purpose Of GrantPurposeOfGrantTxt	Cash GrantCashGrantAmt	Manner Of Cash DisbursementMannerOfCashDisbursementTxt	Valuation Method UsedValuationMethodUsedDesc
Europe (Including Iceland and Greenland)	RESEARCH	$63,445	CHECK & WIRE	CASH
Europe (Including Iceland and Greenland)	RESEARCH	$75,000	WIRE	CASH
North America	RESEARCH	$25,000	WIRE	CASH
East Asia and the Pacific	RESEARCH	$24,000	WIRE	CASH

Field	Value	IRS element (for citing)
Total501c3 Org	2	Total501c3OrgCnt
Total Other Org	3	TotalOtherOrgCnt
Transfer To Foreign Corp	false	TransferToForeignCorpInd
Interest In Foreign Trust	false	InterestInForeignTrustInd
Foreign Corp Ownership	false	ForeignCorpOwnershipInd
Passive Foreign Investmest Co	false	PassiveForeignInvestmestCoInd
Foreign Partnership	false	ForeignPartnershipInd
Boycott Countries	false	BoycottCountriesInd

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	PART I, LINE 2:	FormAndLineReferenceDesc
Explanation	GRANTEE ORGANIZATIONS ARE EXPECTED TO FILE ANNUAL PROGRESS REPORTS TO OUTLINED GRANT GOALS AND MILESTONES. THESE REPORTS ARE REVIEWED BY A COMMITTEE OF PEERS. THIS COMMITTEE MAKES DETERMINATIONS BASED ON QUALITY OF WORK TO GOALS IF THE GRANTEE ORGANIZATION WILL CONTINUE TO RECEIVE FUNDING. A FINAL WRITTEN AND FINANCIAL REPORT IS REQUIRED OF ALL GRANTEES.	ExplanationTxt

Schedule G IRS990ScheduleG

Fundraising Event Information FundraisingEventInformationGrp

Field	Value	IRS element (for citing)
Event1	walks	Event1Nm
Gross Receipts Event1	$1,052,858	GrossReceiptsEvent1Amt
Charitable Contri Event1	$937,858	CharitableContriEvent1Amt
Gross Revenue Event1	$115,000	GrossRevenueEvent1Amt
Non Cash Prizes Event1	$25,309	NonCashPrizesEvent1Amt
Rent Facility Costs Event1	$20,104	RentFacilityCostsEvent1Amt
Food And Beverage Event1	$4,664	FoodAndBeverageEvent1Amt
Entertainment Event1	$4,709	EntertainmentEvent1Amt
Event2	comedy for cure	Event2Nm
Gross Receipts Event2	$199,449	GrossReceiptsEvent2Amt
Charitable Contri Event2	$174,127	CharitableContriEvent2Amt
Gross Revenue Event2	$25,322	GrossRevenueEvent2Amt
Non Cash Prizes Event2	$196	NonCashPrizesEvent2Amt
Rent Facility Costs Event2	$9,885	RentFacilityCostsEvent2Amt
Food And Beverage Event2	$25,449	FoodAndBeverageEvent2Amt
Entertainment Event2	$1,186	EntertainmentEvent2Amt
Other Events Total	9	OtherEventsTotalCnt
Gross Receipts Other Events	$182,042	GrossReceiptsOtherEventsAmt
Charitable Contri Other Events	$172,698	CharitableContriOtherEventsAmt
Gross Revenue Other Events	$9,344	GrossRevenueOtherEventsAmt
Non Cash Prizes Other Events	$1,168	NonCashPrizesOtherEventsAmt
Rent Fclty Costs Other Events	$200	RentFcltyCostsOtherEventsAmt
Food And Beverage Other Events	$11,574	FoodAndBeverageOtherEventsAmt
Entertainment Other Events	$732	EntertainmentOtherEventsAmt
Gross Receipts Total	$1,434,349	GrossReceiptsTotalAmt
Charitable Contributions Tot	$1,284,683	CharitableContributionsTotAmt
Gross Revenue Total Events	$149,666	GrossRevenueTotalEventsAmt
Non Cash Prizes Total Events	$26,673	NonCashPrizesTotalEventsAmt
Rent Fclty Costs Total Events	$30,189	RentFcltyCostsTotalEventsAmt
Food And Beverage Total Events	$41,687	FoodAndBeverageTotalEventsAmt
Entertainment Total Events	$6,627	EntertainmentTotalEventsAmt
Direct Expense Summary Events	$105,176	DirectExpenseSummaryEventsAmt
Net Income Summary	$44,490	NetIncomeSummaryAmt

Schedule I IRS990ScheduleI

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (true)	GrantRecordsMaintainedInd

Recipient Table RecipientTable (10 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	Recipient EINRecipientEIN	IRC SectionIRCSectionDesc	Cash GrantCashGrantAmt	Purpose Of GrantPurposeOfGrantTxt
BRIGHAM & WOMEN'S HOSPITAL
75 ST FRANCIS STREET	BOSTON	MA	02115	042312909	501(C)(3)	$68,750	RESEARCH GRANTS
HARVARD TH CHAN SCHOOL OF PUBLIC HEALTH
PO BOX 415649	BOSTON	MA	02241	042103580	501(C)(3)	$100,000	RESEARCH GRANT
UC BERKELEY
2150 SHATTUCK AVE 300	BERKELEY	CA	94704	946002123	501(C)(3)	$75,000	RESEARCH GRANT
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER
5323 HARRY HINES BLVD	DALLAS	TX	75287	756002868	501(C)(3)	$18,750	RESEARCH GRANT
BOSTON CHILDREN'S HOSPITAL
RSRCH FIN PO BOX 414413	BOSTON	MA	02241	042774441	501(C)(3)	$225,000	RESEARCH GRANTS
AMERICAN EPILEPSY SOCIETY
135 SOUTH LASALLE ST	CHICAGO	IL	60603	046112600	501(C)(3)	$40,000	RESEARCH GRANT
CHILDREN'S HOSPITAL LOS ANGELES
4650 SUNSET BLVD	LOS ANGELES	CA	90027	959121916	501(C)(3)	$56,250	RESEARCH GRANT
CHILDREN'S HOSPITAL MEDICAL CENTER
3333 BURNET AVENUE	CINCINNATI	OH	45229	310833936	501(C)(3)	$50,000	RESEARCH GRANT
PRESIDENT & FELLOWS OF HARVARD COLLEGE
PO BOX 415649	BOSTON	MA	042103580	042103580	501(C)(3)	$56,250	RESEARCH GRANT
YALE UNIVERSITY
PO BOX 1873	NEW HAVEN	CT	06508	060646973	501(C)(3)	$56,250	RESEARCH GRANT

Field	Value	IRS element (for citing)
Total501c3 Org	9	Total501c3OrgCnt

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	PART I, LINE 2:	FormAndLineReferenceDesc
Explanation	THE TS ALLIANCE HAS FUNDED MORE THAN $19.7 MILLION IN RESEARCH ON TSC SINCE 1984. DIRECTED BY STEVEN L. ROBERDS, PH.D, CHIEF SCIENTIFIC OFFICER, THE TS ALLIANCE RESEARCH GRANTS PROGRAM FUNDS RESEARCH FOCUSED ON TSC WITH PRIORITIES SET BY THE RESEARCHERS TOGETHER WITH THE TS ALLIANCE. COLLABORATIONS BETWEEN BASIC AND CLINICAL RESEARCHERS ARE ENCOURAGED AND FOSTERED, AND THE TS ALLIANCE IS WORKING TO INCREASE FUNDING FOR RESEARCH ON TSC. THROUGH THE TS ALLIANCE RESEARCH GRANTS PROGRAM, APPLICATIONS CAN BE SUBMITTED FOR: - POSTDOCTORAL FELLOWSHIPS - TSC RESEARCH GRANTS GRANTS ARE REVIEWED IN A THREE-STEP PROCESS: - A GRANT REVIEW COMMITTEE COMPOSED OF INDIVIDUALS KNOWLEDGEABLE ABOUT THE CLINICAL AND BASIC COMPONENTS OF TSC, REVIEW ALL GRANT APPLICATIONS FOR SCIENTIFIC MERIT, RELEVANCY TO THE FUNDING PRIORITIES OF THE ORGANIZATION AND WITH A FOCUS ON UNDERSTANDING THE MECHANISMS OF TSC AND/OR THE DEVELOPMENT OF TREATMENTS AND THERAPIES FOR THE MANIFESTATIONS OF THE DISEASE. - THE SCIENCE AND MEDICAL COMMITTEE OF THE BOARD OF DIRECTORS THEN REVIEWS THE GRANT REVIEW COMMITTEE'S CONCLUSIONS AND MAKES FUNDING RECOMMENDATIONS TO THE BOARD OF DIRECTORS. - THE BOARD OF DIRECTORS THEN REVIEWS THE RECOMMENDATIONS OF THE SCIENCE AND MEDICAL COMMITTEE AND MAKES FINAL APPROVAL FOR THE FUNDING OF GRANT APPLICATIONS.	ExplanationTxt

Schedule J IRS990ScheduleJ

Field	Value	IRS element (for citing)
Compensation Committee	Yes (X)	CompensationCommitteeInd
Form990 Of Other Organizations	Yes (X)	Form990OfOtherOrganizationsInd
Compensation Survey	Yes (X)	CompensationSurveyInd
Board Or Committee Approval	Yes (X)	BoardOrCommitteeApprovalInd
Severance Payment	false	SeverancePaymentInd
Supplemental Nonqual Rtr Plan	false	SupplementalNonqualRtrPlanInd
Equity Based Comp Arrngm	false	EquityBasedCompArrngmInd
Comp Based On Revenue Of Flng Org	Yes (true)	CompBasedOnRevenueOfFlngOrgInd
Comp Bsd On Rev Related Orgs	false	CompBsdOnRevRelatedOrgsInd
Comp Bsd Net Earns Flng Org	Yes (true)	CompBsdNetEarnsFlngOrgInd
Comp Bsd Net Earns Rltd Orgs	false	CompBsdNetEarnsRltdOrgsInd
Any Non Fixed Payments	false	AnyNonFixedPaymentsInd
Initial Contract Exception	false	InitialContractExceptionInd

Rltd Org Officer Trst Key Empl RltdOrgOfficerTrstKeyEmplGrp (3 entries)

TitleTitleTxt	Base Compensation Filing OrgBaseCompensationFilingOrgAmt	Compensation Based On Rltd OrgsCompensationBasedOnRltdOrgsAmt	Bonus Filing OrganizationBonusFilingOrganizationAmount	Deferred Compensation Flng OrgDeferredCompensationFlngOrgAmt	Deferred Comp Rltd OrgsDeferredCompRltdOrgsAmt	Nontaxable Benefits Filing OrgNontaxableBenefitsFilingOrgAmt	Nontaxable Benefits Rltd OrgsNontaxableBenefitsRltdOrgsAmt	Total Compensation Filing OrgTotalCompensationFilingOrgAmt	Total Compensation Rltd OrgsTotalCompensationRltdOrgsAmt	Comp Report Prior990 Filing OrgCompReportPrior990FilingOrgAmt	Comp Report Prior990 Rltd OrgsCompReportPrior990RltdOrgsAmt
KARI L ROSEBECK
PRESIDENT & CEO	$159,924	$0	$10,792	$5,296	$0	$24,028	$0	$200,040	$0	$0	$0
RICHARD A GOLLUB
CONTROLLER & CFO	$124,917	$0	$7,800	$4,191	$0	$29,153	$0	$166,061	$0	$0	$0
STEVEN L ROBERDS
CHIEF SCIENTIFIC OFFICER	$172,812	$0	$12,173	$5,747	$0	$26,108	$0	$216,840	$0	$0	$0

Supplemental Information Detail SupplementalInformationDetail (3 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
PART I, LINE 5A:	KARI LUTHER ROSBECK, RICHARD GOLLUB, STEVE ROBERDS AND JAYE ISHAM ALL HAVE INCENTIVE COMPENSATION EQUAL TO A PERCENTAGE OF THEIR SALARIES BASED ON KEY PERFORMANCE OBJECTIVES AS ESTABLISHED BY THE COMPENSATION COMMITTEE.
PART I, LINE 6A:	KARI LUTHER ROSBECK, RICHARD GOLLUB, STEVE ROBERDS AND JAYE ISHAM ALL HAVE INCENTIVE COMPENSATION EQUAL TO A PERCENTAGE OF THEIR SALARIES BASED ON KEY PERFORMANCE OBJECTIVES AS ESTABLISHED BY THE COMPENSATION COMMITTEE.
PART I & PART II:	KARI LUTHER ROSBECK AND RICHARD GOLLUB ARE EMPLOYEES OF TUBEROUS SCLEROSIS ALLIANCE AND ARE COMPENSATED THROUGH TS ALLIANCE. THESE INDIVIDUALS SERVE THE ENDOWMENT WITHOUT COMPENSATION.

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (9 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
FORM 990, PART III, LINE 4D, OTHER PROGRAM SERVICES:	Government Relations focuses on educating members of Congress about TSC to further TSC research, awareness and clinical care. The annual TS Alliance March on Capitol Hill to advocate for federal funding for the Tuberous Sclerosis Complex Research Program (TSCRP) at the Department of Defenses (DoD) Congressionally Directed Medical Research Program (CDMRP) took place in early March 2016. More than 100 members of the TSC community participated and asked their senators and representatives to sign onto Dear Colleague letters in support of the TSCRP. Many other advocates who were not able to travel to Washington, DC met with their senators and representatives back in their home states to make the case for continued funding. In the House, 165 Democratic and Republican Representatives signed a bipartisan Dear Colleague letter of support from Representatives Loretta Sanchez (D-CA) and Mike Fitzpatrick (R-PA). The Senate letter was sponsored by Senators Chris Murphy (D-CT) and Johnny Isakson (R-GA) and ended with 25 signatures. In FY2016, the TSC Research Program at the CDMRP received a $6 million appropriation, bringing the cumulative funding to $65 million since 2002 as a result of our successful grassroots efforts. Funding for FY2017 is pending on Congress passing the FY2017 budget but is currently included at $6 million. A $2 million increase over past years was added as an amendment put forth by Rep. Fitzpatrick during the House floor debate on the Defense Appropriations Act on June 15, 2016, but was removed in conference committee. Research performed through this program has recently led to additional clinical trials including determining if imatinib, a drug FDA-approved for cancer, can safely improve levels of VEGF-D, a biomarker of lymphangioleiomyomatosis (LAM), a life-threatening lung manifestation of TSC, funded in FY2013; testing a combination of two drugs to treat LAM funded in FY2012; a multi-site clinical trial testing the efficacy of an experimental topical rapamycin cream to treat the disfiguring facial tumors, called facial angiofibromas, caused by TSC funded in FY2010; a clinical research network was created to test potential new therapies, to validate biomarkers, and to learn the natural history of leading to a clinical trial funded in FY2012. Building upon FY2010-funded research on glutamate receptors (mGluR5), several companies are now looking at the link between cognitive impairments in TSC to autism, anxiety, and other mental disorders. The TSCRP has also funded research to develop animal models of TSC that have seizures, enabling a better understanding of the etiology of TSC. Based on data from TSCRP-funded animal models of TSC that have seizures and share pathology related to that of traumatic brain injury, an industry-sponsored clinical trial demonstrated the effectiveness the mTOR inhibitor, everolimus, at treating epilepsy in many individuals with TSC. None of this progress would have been possible without the critical support provided through the TSCRP. Additional Government Relations efforts included a Congressional Briefing on Capitol Hill on March 2, 2016. Congressional staff and key members of the TSC research and grassroots communities attended the event. Professional Education expands programs to target researchers and healthcare providers caring for individuals with TSC, medical students, genetic counselors and educators to minimize the consequences of ignorance and misinformation. The TS Alliance participated in and presented at 27 professional meetings including: The Child Neurology Society Meeting; LAMposium and the LAM and Rare Lung Disease Conference; World Orphan Drug Congress; Association of Clinical Research Professionals Conference; Interagency Collaborative To Advance Research In Epilepsy (ICARE); FDA Patient Engagement Workshop; Partners Against Mortality in Epilepsy (PAME) Conference; 2016 Vancouver TSC Educational Conference in British Columbia; The NINDS Nonprofit Forum; Disability Policy Seminar; the Indication Expansion and Drug Repurposing Summit; CBIs Patient Registries Summit; 3rd Rare Disease Collaborative Summit hosted by EXL Events; Society for Neuroscience Annual Meeting; BIO Patient and Health Advocacy Summit; NORD Summit; the International TSC Research Conference in Portugal; and the American Thoracic Society. In addition, at the American Epilepsy Society (AES) annual meeting the TS Alliance hosted an Infantile Spasms Awareness Innovation Pavilion exhibit and a TSC reception for more than 100 researchers, clinicians, and community members. The TS Alliance also participated in two Special Interest Group scientific sessions, one on TSC and another on research resources made available by non-profit organizations advocating for rare disorders that involve epilepsy. Further, the Vice President of Outreach has ongoing collaboration with national educational networks, such as the Association for Middle Level Education (AMLE). She also collaborates with Parent Training Information Centers (PTIs) throughout the country. Providing children with appropriate education is one key to individuals having a good quality of life. EXPENSES $211,911. INCLUDING GRANTS OF $-0- REVENUES $17,900.
FORM 990, PART VI, SECTION A, LINE 6:	MEMBERSHIP IS AVAILABLE TO ANY PERSON WHO SUBSCRIBES TO THE PURPOSES AND OBJECTIVES OF THE CORPORATION, WITHOUT REGARD TO RACE, RELIGION, GENDER, SEXUAL ORIENTATION, AGE, COLOR, NATIONAL ORIGIN OR MENTAL OR PHYSICAL HANDICAP OR DISABILITY. THERE SHALL BE NO LIMIT TO THE NUMBER OF MEMBERS IN THE CORPORATION. 1) THERE MAY BE ONE OR MORE CLASSES OF MEMBERSHIP AS DETERMINED BY THE BOARD. 2) MEMBERSHIP IS NOT TRANSFERABLE OR ASSIGNABLE.
FORM 990, PART VI, SECTION A, LINE 7A:	THE TS ALLIANCE IS A MEMBERSHIP-BASED ORGANIZATION, WHICH MEANS MEMBERS HELP ELECT THE BOARD OF DIRECTORS. THE TS ALLIANCE MEMBERSHIP PROGRAM ALLOWED INDIVIDUALS TO STATE THEIR INTENT TO BE A MEMBER FOR THE PURPOSE OF GOVERNANCE. THERE WERE NO LEVELS TO MEMBERSHIP IN 2016. ANYONE CAN BE A MEMBER AT NO COST.
FORM 990, PART VI, SECTION B, LINE 11:	THE FORM 990 IS REVIEWED, IN DETAIL, BY THE BOARD OF DIRECTORS AUDIT AND FINANCE COMMITTEES. RECOMMENDATIONS ARE MADE BY THE COMMITTEE MEMBERS FOR ANY CHANGES/EDITS/ADDITIONS. AFTER THOSE HAVE BEEN INCORPORATED BOTH COMMITTEES VOTE WHETHER TO APPROVE AND THEN FORWARD THE 990 TO THE EXECUTIVE COMMITTEE. THE EXECUTIVE COMMITTEE PERFORMS THE FINAL REVIEW AND THEN VOTES WHETHER TO APPROVE ON BEHALF OF THE BOARD OF DIRECTORS. A COPY OF THE APPROVED 990 IS SHARED WITH THE ENTIRE BOARD.
FORM 990, PART VI, SECTION B, LINE 12C:	ANNUALLY EACH MEMBER OF THE BOARD OF DIRECTORS WILL RECEIVE NOTICE OF THE ORGANIZATION'S CONFLICT OF INTEREST STATEMENT. EACH MEMBER WILL BE PROVIDED WITH A STATEMENT TO MAKE DISCLOSURE OF ANY POTENTIAL CONFLICT OF INTEREST. IF DURING THE COURSE OF THE YEAR A POTENTIAL CONFLICT OF INTEREST ARISES THAT HAS NOT PREVIOUSLY BEEN DISCLOSED, THE BOARD MEMBERS WILL MAKE WRITTEN NOTICE OF A POTENTIAL CONFLICT OF INTEREST AND RECUSE HIMSELF OR HERSELF FROM ANY DISCUSSIONS AND VOTES IN CONNECTION WITH THE ISSUE IDENTIFIED. ANY TIME A MEMBER IS RECUSED FROM DISCUSSION ON AN ISSUE, THE MINUTES OF COMMITTEE MEETING AND BOARD MEETING WILL DULY RECORD SUCH ACTIONS. THE FOLLOWING POTENTIAL CONFLICTS OF INTEREST WERE DISCLOSED FOR 2016: BOARD MEMBER BRENDAN MANNING, PH.D, IS EMPLOYED AT HARVARD COLLEGE, WHICH RECEIVED $100,000 ROTHBERG COURAGE AWARD GRANT TO STUDY REPURPOSING APPROVED INHIBITORS OF PURINE SYNTHESIS FOR TSC TREATMENT. BOARD MEMBER MARTINA BEBIN, MD IS EMPLOYED BY THE UNIVERSITY OF ALABAMA BIRMINGHAM, WHICH RECEIVED A $19,800 FEE FOR SERVICE FOR ENTERING DATA INTO THE NATURAL HISTORY DATABASE. COMMITTEE MEETING AND BOARD MEETING WILL DULY RECORD SUCH ACTIONS.
FORM 990, PART VI, SECTION B, LINE 15:	THE COMPENSATION COMMITTEE REVIEWS AND APPROVES THE SALARIES OF THE PRESIDENT/CEO, CHIEF SCIENTIFIC OFFICER, CONTROLLER & CFO, AND ANY EMPLOYEE APPEARING ON THE FORM 990, IN ACCORDANCE WITH THE TUBEROUS SCLEROSIS ALLIANCE BYLAWS. SUCH REVIEW AND APPROVAL OCCURS INITIALLY UPON HIRING, UPON ANNUAL REVIEWS AND WHENEVER MODIFIED. THE ORGANIZATION'S EXECUTIVE REMUNERATION HAS BEEN STRUCTURED TO ENSURE THAT IT: IS REASONABLE; PROVIDES A COMPETITIVE COMPENSATION PROGRAM TO RETAIN, ATTRACT AND REWARD KEY EMPLOYEES AND ACHIEVES CLEAR ALIGNMENT BETWEEN TOTAL REMUNERATION AND DELIVERED BUSINESS AND PERSONAL PERFORMANCE OVER THE SHORT AND LONG-TERMS. THE COMPENSATION IS REVIEWED BY THE COMPENSATION COMMITTEE TO ENSURE: - COMPARABILITY, - PROPER REVIEW, AND - SUBSTANTIATION IN SETTING THE COMPENSATION.
FORM 990, PART VI, SECTION C, LINE 19:	ALL GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY AND FINANCIAL STATEMENTS ARE AVAILABLE UPON WRITTEN REQUEST.
FORM 990, PART XI, LINE 9, CHANGES IN NET ASSETS:	CHANGE IN INTEREST IN AFFLIIATE $530,471.
FORM 990, PART XII, LINE 2C	THE AUDIT REVIEW PROCESS HAS REMAINED UNCHANGED FROM THE PRIOR YEAR.

Schedule R IRS990ScheduleR

Id Related Tax Exempt Org IdRelatedTaxExemptOrgGrp

Disregarded Entity Name DisregardedEntityName

Field	Value	IRS element (for citing)
Business Name Line1	TUBEROUS SCLEROSIS ALLIANCE ENDOWMENT FD	BusinessNameLine1Txt

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	801 ROEDER ROAD STE 750	AddressLine1Txt
City	SILVER SPRING	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20910	ZIPCd

Field	Value	IRS element (for citing)
EIN	521926919	EIN
Primary Activities	SUPPORT ORG	PrimaryActivitiesTxt
Legal Domicile State	MD	LegalDomicileStateCd
Exempt Code Section	501(C)(3)	ExemptCodeSectionTxt
Public Charity Status	11B, III	PublicCharityStatusTxt
Direct Controlling NA	N/A	DirectControllingNACd
Controlled Organization	false	ControlledOrganizationInd

Field	Value	IRS element (for citing)
Receipt Of Int Annts Rnts Rylts	false	ReceiptOfIntAnntsRntsRyltsInd
Gift Grnt Or Cap Contri To Oth Org	false	GiftGrntOrCapContriToOthOrgInd
Gift Grnt Cap Contri From Oth Org	false	GiftGrntCapContriFromOthOrgInd
Loans Or Guarantees To Other Org	false	LoansOrGuaranteesToOtherOrgInd
Loans Or Guarantees From Oth Org	false	LoansOrGuaranteesFromOthOrgInd
Div Related Organization	false	DivRelatedOrganizationInd
Asset Sale To Other Org	false	AssetSaleToOtherOrgInd
Asset Purchase From Other Org	false	AssetPurchaseFromOtherOrgInd
Asset Exchange	false	AssetExchangeInd
Rental Of Facilities To Oth Org	false	RentalOfFacilitiesToOthOrgInd
Rental Of Fclts From Oth Org	false	RentalOfFcltsFromOthOrgInd
Perform Of Services For Oth Org	false	PerformOfServicesForOthOrgInd
Perform Of Services By Other Org	false	PerformOfServicesByOtherOrgInd
Sharing Of Facilities	Yes (true)	SharingOfFacilitiesInd
Paid Employees Sharing	Yes (true)	PaidEmployeesSharingInd
Reimbursement Paid To Other Org	false	ReimbursementPaidToOtherOrgInd
Reimbursement Paid By Other Org	false	ReimbursementPaidByOtherOrgInd
Transfer To Other Org	false	TransferToOtherOrgInd
Transfer From Other Org	false	TransferFromOtherOrgInd