HOWARD HUGHES MEDICAL INSTITUTE: Form 990, tax year 2016

View the entire original 990 at ProPublica ↗

Organization: HOWARD HUGHES MEDICAL INSTITUTE (EIN 59-0735717)
Tax period: 2016-09-01 to 2017-08-31
Filed: 2018-04-20
IRS object ID: 201801109349300120
Schema version: 2016v3.0
Source: Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header
Form 990
Schedule A
Schedule B
Schedule C
Schedule D
Schedule F
Schedule I
Schedule J
Schedule K
Schedule K
Schedule O
Schedule R

Return header ReturnHeader

Field	Value	IRS element (for citing)
Return	2018-04-20T15:00:13-05:00	ReturnTs
Tax Period End	2017-08-31	TaxPeriodEndDt

Preparer Firm PreparerFirmGrp

Field	Value	IRS element (for citing)
Preparer Firm EIN	134008324	PreparerFirmEIN

Preparer Firm Name PreparerFirmName

Field	Value	IRS element (for citing)
Business Name Line1	PRICEWATERHOUSECOOPERS LLP	BusinessNameLine1Txt

Preparer US Address PreparerUSAddress

Field	Value	IRS element (for citing)
Address Line1	600 13TH STREET NW STE 1000	AddressLine1Txt
City	WASHINGTON	CityNm
State Abbreviation	DC	StateAbbreviationCd
ZIP	20005	ZIPCd

Field	Value	IRS element (for citing)
Return Type	990	ReturnTypeCd
Tax Period Begin	2016-09-01	TaxPeriodBeginDt

Filer Filer

Field	Value	IRS element (for citing)
EIN	590735717	EIN

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	Howard Hughes Medical Institute	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Business Name Control	HOWA	BusinessNameControlTxt
Phone	3012158500	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	4000 JONES BRIDGE ROAD	AddressLine1Txt
City	CHEVY CHASE	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20815	ZIPCd

Business Officer BusinessOfficerGrp

Field	Value	IRS element (for citing)
Person	Monique L Marcus	PersonNm
Person Title	Controller	PersonTitleTxt
Signature	2018-04-20	SignatureDt
Discuss With Paid Preparer	Yes (true)	DiscussWithPaidPreparerInd

Preparer Person PreparerPersonGrp

Field	Value	IRS element (for citing)
Preparer Person	Marci Krause	PreparerPersonNm
Phone	2024141000	PhoneNum

Field	Value	IRS element (for citing)
Tax	2016	TaxYr
Build TS	2021-01-29 14:40:06Z	BuildTS

Form 990 IRS990

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	4000 JONES BRIDGE ROAD	AddressLine1Txt
City	CHEVY CHASE	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20815	ZIPCd

Field	Value	IRS element (for citing)
Gross Receipts	$48,467,077,301	GrossReceiptsAmt
Group Return For Affiliates	false	GroupReturnForAffiliatesInd
Organization501c3	Yes (X)	Organization501c3Ind
Website Address	WWW.HHMI.ORG	WebsiteAddressTxt
Type Of Organization Corp	Yes (X)	TypeOfOrganizationCorpInd
Formation	1953	FormationYr
Legal Domicile State	DE	LegalDomicileStateCd
Activity Or Mission	THE HOWARD HUGHES MEDICAL INSTITUTE IS A PHILANTHROPY THAT SERVES SOCIETY THROUGH THE DIRECT CONDUCT OF BIOMEDICAL RESEARCH AND SUPPORT FOR PROGRAMS IN SCIENCE EDUCATION.	ActivityOrMissionDesc
Voting Members Governing Body	10	VotingMembersGoverningBodyCnt
Voting Members Independent	10	VotingMembersIndependentCnt
Total Employee	3255	TotalEmployeeCnt
Total Volunteers	0	TotalVolunteersCnt
Total Gross UBI	$19,685,078	TotalGrossUBIAmt
Net Unrelated Bus Txbl Incm	$0	NetUnrelatedBusTxblIncmAmt
PY Contributions Grants	$19,321,241	PYContributionsGrantsAmt
CY Contributions Grants	$961,418	CYContributionsGrantsAmt
PY Program Service Revenue	$2,223,162	PYProgramServiceRevenueAmt
CY Program Service Revenue	$2,593,242	CYProgramServiceRevenueAmt
PY Investment Income	$921,724,327	PYInvestmentIncomeAmt
CY Investment Income	$1,525,605,714	CYInvestmentIncomeAmt
PY Other Revenue	$257,052,143	PYOtherRevenueAmt
CY Other Revenue	$21,387,517	CYOtherRevenueAmt
PY Total Revenue	$1,200,320,873	PYTotalRevenueAmt
CY Total Revenue	$1,550,547,891	CYTotalRevenueAmt
PY Grants And Similar Paid	$138,793,048	PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid	$94,758,743	CYGrantsAndSimilarPaidAmt
CY Benefits Paid To Members	$0	CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid	$438,554,171	PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid	$405,021,233	CYSalariesCompEmpBnftPaidAmt
CY Total Prof Fndrsng Expns	$0	CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense	$0	CYTotalFundraisingExpenseAmt
PY Other Expenses	$556,129,969	PYOtherExpensesAmt
CY Other Expenses	$543,673,945	CYOtherExpensesAmt
PY Total Expenses	$1,133,477,188	PYTotalExpensesAmt
CY Total Expenses	$1,043,453,921	CYTotalExpensesAmt
PY Revenues Less Expenses	$66,843,685	PYRevenuesLessExpensesAmt
CY Revenues Less Expenses	$507,093,970	CYRevenuesLessExpensesAmt
Total Assets BOY	$21,082,502,290	TotalAssetsBOYAmt
Total Assets EOY	$22,594,415,758	TotalAssetsEOYAmt
Total Liabilities BOY	$3,306,942,737	TotalLiabilitiesBOYAmt
Total Liabilities EOY	$3,285,217,733	TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY	$17,775,559,553	NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY	$19,309,198,025	NetAssetsOrFundBalancesEOYAmt
Mission	THE HOWARD HUGHES MEDICAL INSTITUTE ("INSTITUTE" OR "HHMI") IS THE NATION'S LARGEST PRIVATE BIOMEDICAL RESEARCH INSTITUTION, WITH JUST OVER $19 BILLION IN NET ASSETS AT THE END OF ITS 2017 FISCAL YEAR. THE MISSION OF THE INSTITUTE HAS REMAINED CONSTANT SINCE ITS FOUNDING IN 1953. AS ITS CHARTER STATES "THE PRIMARY PURPOSE AND OBJECTIVE OF THE HOWARD HUGHES MEDICAL INSTITUTE SHALL BE THE PROMOTION OF HUMAN KNOWLEDGE WITHIN THE FIELD OF BASIC SCIENCES (PRINCIPALLY THE FIELD OF MEDICAL RESEARCH AND EDUCATION) AND THE EFFECTIVE APPLICATION THEREOF FOR THE BENEFIT OF MANKIND."	MissionDesc
Significant New Program Srvc	false	SignificantNewProgramSrvcInd
Significant Change	false	SignificantChangeInd
Expense	$659,754,981	ExpenseAmt
Revenue	$2,552,736	RevenueAmt
Desc	MEDICAL RESEARCH ORGANIZATION ACTIVITIES (A) THE HHMI INVESTIGATOR PROGRAM (B) JANELIA RESEARCH CAMPUS (C) HIGHLIGHTS FROM HHMI RESEARCH LABORATORIES (FISCAL YEAR 2017) (D) HONORS AND AWARDS RECEIVED BY HHMI SCIENTISTS (A) THE HHMI INVESTIGATOR PROGRAM The Howard Hughes Medical Institute's approach to biomedical research can be summarized in three words: people, not projects. By employing scientists as HHMI investigators - rather than awarding research grants - the Institute provides long-term, flexible funding that enables its researchers to pursue their scientific interests wherever they lead. HHMI believes that scientists of exceptional talent and imagination will make fundamental discoveries of lasting scientific value and benefit to humanity if they are given the resources, time, and freedom to pursue challenging questions. The Institute nurtures the creativity and intellectual daring of scientists who are willing to set aside conventional wisdom or the "easy" question for a fundamental problem that may take many years to solve. Among the characteristics that distinguish this group of scientists are qualities such as creativity, a penchant for risk-taking, and a commitment to discovery, productivity, and perseverance. This unique research model is an imaginative and powerful alternative to funding biomedical research through grants. The HHMI Investigator Program employs more than 290 HHMI researchers, among them 15 Nobel laureates and 164 members of the National Academy of Sciences. HHMI investigators direct Institute research laboratories on the campuses of 63 universities and other research organizations throughout the United States. Since the early 1990s, investigators have been selected through rigorous national competitions. The Institute solicits applications directly from scientists at medical schools and other research institutions in the United States, with the aim of identifying those who have the potential to make significant contributions to science. HHMI employs an open application process to ensure that it is selecting its researchers from a broad and deep pool of scientific talent. In March 2017, HHMI announced that it would seek to appoint up to 20 new biomedical researchers through a national open competition. HHMI recently increased the standard term for HHMI investigators from five to seven years, providing longer term, flexible support as these scientists explore new research territory. The addition of 20 new investigators to this initiative represents a new investment of approximately $168 million in basic biomedical research over the next seven years. Finalists will be announced in Spring 2018, with appointments starting as early as September 1, 2018. Highlights of research conducted, and awards received, by HHMI scientists during its year ended August 31, 2017 are included below. (B) Janelia Research Campus The Janelia Research Campus offers a collaborative research environment for scientists across an array of disciplines who have focused on two broad scientific areas of scientific inquiry: the identification of general principles governing how neuronal circuits process information and development of imaging technologies and computational methods that support image analysis. In the current fiscal year, there were 42 group leaders, eight fellows and 15 senior fellows at Janelia, in addition to graduate students, other scientific trainees, and visiting scientists. Janelia also operates a vibrant scientific conference program, bringing many scientists to its campus each year for educational meetings.	Desc

Prog Srvc Accom Acty2 ProgSrvcAccomActy2Grp

Field	Value	IRS element (for citing)
Expense	$87,600,256	ExpenseAmt
Grant	$59,883,743	GrantAmt
Revenue	$40,506	RevenueAmt
Desc	SCIENCE EDUCATION AND RESEARCH GRANT PROGRAMS (A) GRADUATE SCIENCE EDUCATION AND MEDICAL RESEARCH TRAINING (B) PRECOLLEGE AND UNDERGRADUATE SCIENCE EDUCATION PROGRAM (C) EDUCATIONAL MEDIA (D) TANGLED BANK STUDIOS (E) HANNA GRAY FELLOWS (F) FACULTY SCHOLARS (G) E-LIFE OPEN ACCESS JOURNAL HHMI'S DEPARTMENT OF SCIENCE EDUCATION EMPHASIZES INITIATIVES WITH THE POWER TO TRANSFORM GRADUATE, UNDERGRADUATE, AND PRECOLLEGE EDUCATION IN THE LIFE SCIENCES. HHMI IS THE LARGEST PRIVATE FUNDER OF SCIENCE EDUCATION IN THE UNITED STATES. DURING THE FISCAL YEAR, THE INSTITUTE DISTRIBUTED $38 MILLION IN GRANTS TO SUPPORT SCIENCE EDUCATION. The Institute's science education programs support ties between scientific research and teaching with the goal of increasing and enhancing student research opportunities; improving science courses, curricula, and instruction; and providing enhanced graduate and medical training opportunities. Most HHMI grants are awarded through competitions with specific objectives and eligibility criteria and awards are made following a stringent process of peer review. HHMI's educational activities are funded through three major programs; the goals of each program and the major activities for the year are summarized below. (A) Undergraduate Science Education Program These programs recruit and develop the future leaders of science and enhance science literacy among all students. Precollege grants support teacher training and inquiry-based student learning. Grants to colleges and universities support undergraduate student research, faculty and curriculum development, and science education outreach activities. In June, 2017, HHMI announced the first 24 schools selected in its Inclusive Excellence initiative. The initiative's broad objective is to help colleges and universities to increase their capacity for inclusion in science of all students, especially those students who come to college via non-traditional pathways. These "new majority" students include underrepresented ethnic minorities, first-generation college students, students who transfer from community colleges, and working adults with families. Inclusive Excellence is not simply making sure everyone can participate; rather, it means that the institution makes it clear that the students are welcome and are expected to succeed. HHMI continued its partnership with the University of Maryland, Baltimore County (UMBC), the Pennsylvania State University, and the University of North Carolina at Chapel Hill (UNC), in the collaborative Meyerhoff Adaptation Project. The project aims to learn whether elements of UMBC's highly regarded Meyerhoff Scholars Program can be adapted at Penn State and UNC. The participating schools hope to share what they learn so other institutions might follow. During the five-year Meyerhoff Adaptation Project, Penn State and UNC, working closely with UMBC and HHMI, will expand and study the Meyerhoff model, while applying it to newly created programs on their campuses. The HHMI Professors Program empowers accomplished science faculty at leading research universities to apply the rigor and creativity that make them successful in research to important challenges in undergraduate science education. The professors model fundamental reform in the way undergraduate science is taught at research universities through innovative teaching and are encouraged to share ideas and collaborate with their peers to improve science education. Fifty-five scientists have been named HHMI professors since the program began in 2002. In addition to their commitment to student learning, these highly visible scientists have developed new educational resources and implemented novel mentoring programs to support students. In FY2018, HHMI will make awards to a new cohort of HHMI professors. The HHMI's Exceptional Research Opportunities Program (EXROP) is designed to encourage talented students to pursue careers in science by placing selected undergraduates in summer research experiences in the labs of HHMI investigators, professors, and at the Janelia Research Campus. In 2017, a total of 85 college students (63 first-year students and 22 second-year, "EXROP Capstone" students) were selected to participate in EXROP. The 2017 cohort marked the 15th year of the program.	Desc

Prog Srvc Accom Acty3 ProgSrvcAccomActy3Grp

Field	Value	IRS element (for citing)
Expense	$35,913,012	ExpenseAmt
Grant	$34,875,000	GrantAmt
Desc	SUPPORT FOR INTERNATIONAL SCIENCE (A) NEW INTERNATIONAL RESEARCH SCHOLARS PROGRAM (B) SENIOR INTERNATIONAL RESEARCH SCHOLARS PROGRAM (C) INTERNATIONAL EARLY CAREER SCIENTIST PROGRAM (D) AFRICA HEALTH RESEARCH INSTITUTE IN SOUTH AFRICA (A) New International Research Scholars Program Forty-one scientists from 16 countries have been chosen as International Research Scholars, exceptional early-career scientists poised to advance biomedical research across the globe. HHMI teamed up with the Bill & Melinda Gates Foundation, the Wellcome Trust, and the Calouste Gulbenkian Foundation to develop scientific talent around the world, and will award a total of nearly $26.7 million to this group of scholars. Each researcher will receive a total of $650,000 over five years. The award is a big boon for scientists early in their careers, and offers the freedom to pursue new research directions and creative projects that could develop into top-notch scientific programs. (B) Senior International Research Scholars Program HHMI continues to support 13 of the world's leading basic science researchers as Senior International Research Scholar (SIRS). The awards support outstanding biomedical scientists working outside the United States who have made significant contributions to fundamental research in the biological sciences. The SIRS awardees, selected from a group of previous HHMI international research scholars, are respected leaders in their fields. Each HHMI senior international research scholar receives a grant of $100,000 per year over five years, and presents their research at scientific meetings held at HHMI. The gatherings are intended to facilitate the exchange of ideas, stimulate new research, and provide an opportunity for collaboration with other HHMI scientists. The senior international research scholars' participation helps strengthen the growing network of international biomedical researchers. (C) International Early Career Scientist Program HHMI continues to support 24 international early career scientists who were selected for awards in 2012. Each selected scientist will receive $650,000 over a period of five years with the goal of helping these talented individuals establish independent research programs. In this pilot program, HHMI identified scientists who are, or have the potential to become, scientific leaders. The 24 HHMI international early career scientists conduct research at 20 institutions in 12 countries. Each scientist who was selected had directed his or her own laboratory for less than seven years when they applied to HHMI. The countries represented by the HHMI international early career scientists are Argentina, Brazil, Chile, China, Hungary, India, Italy, Poland, Portugal, South Africa, Spain, and South Korea. (D) Africa Health Research Institute in South Africa In 2009, HHMI helped launch the KwaZulu-Natal Research Institute for TB-HIV (K-RITH) in collaboration with the University of KwaZulu-Natal (UKZN), and has provided significant funding to support its research efforts. In 2016, in a move to improve the health of people locally and globally, K-RITH joined forces with the Africa Centre for Population Health to form a groundbreaking new interdisciplinary institute to fight tuberculosis (TB), HIV and related diseases. The new organization, the Africa Health Research Institute (AHRI), is located at the heart of South Africa's TB and HIV co-epidemic in KwaZulu-Natal Province. The effort brings together the Africa Centre's detailed population data from over 100,000 participants, with K-RITH's expertise in basic science and its world-class laboratory facilities. HHMI, together with the Wellcome Trust, continues to provide grant support to AHRI, with the University College London and UKZN serving as significant academic partners. AHRI is committed to working towards the elimination of HIV and TB. To achieve this, the institute will bring together leading researchers from different fields, use cutting-edge science to improve people's health, and will help to train the next generation of African scientists.	Desc

Field	Value	IRS element (for citing)
Total Program Service Expenses	$783,268,249	TotalProgramServiceExpensesAmt
Described In Section501c3	Yes (true)	DescribedInSection501c3Ind
Schedule B Required	Yes (true)	ScheduleBRequiredInd
Political Campaign Acty	false	PoliticalCampaignActyInd
Lobbying Activities	Yes (true)	LobbyingActivitiesInd
Subject To Proxy Tax	false	SubjectToProxyTaxInd
Donor Advised Fund	false	DonorAdvisedFundInd
Conservation Easements	false	ConservationEasementsInd
Collections Of Art	false	CollectionsOfArtInd
Credit Counseling	false	CreditCounselingInd
Temp Or Permanent Endowments	false	TempOrPermanentEndowmentsInd
Report Land Building Equipment	Yes (true)	ReportLandBuildingEquipmentInd
Report Investments Other Sec	Yes (true)	ReportInvestmentsOtherSecInd
Report Program Related Invst	false	ReportProgramRelatedInvstInd
Report Other Assets	false	ReportOtherAssetsInd
Report Other Liabilities	Yes (true)	ReportOtherLiabilitiesInd
Include FIN48 Footnote	false	IncludeFIN48FootnoteInd
Independent Audit Fincl Stmt	false	IndependentAuditFinclStmtInd
Consolidated Audit Fincl Stmt	Yes (true)	ConsolidatedAuditFinclStmtInd
School Operating	false	SchoolOperatingInd
Foreign Office	false	ForeignOfficeInd
Foreign Activities	Yes (true)	ForeignActivitiesInd
More Than5000 K To Org	Yes (true)	MoreThan5000KToOrgInd
More Than5000 K To Individuals	Yes (true)	MoreThan5000KToIndividualsInd
Professional Fundraising	false	ProfessionalFundraisingInd
Fundraising Activities	false	FundraisingActivitiesInd
Gaming Activities	false	GamingActivitiesInd
Operate Hospital	false	OperateHospitalInd
Grants To Organizations	Yes (true)	GrantsToOrganizationsInd
Grants To Individuals	Yes (true)	GrantsToIndividualsInd
Schedule J Required	Yes (true)	ScheduleJRequiredInd
Tax Exempt Bonds	Yes (true)	TaxExemptBondsInd
Invest Tax Exempt Bonds	false	InvestTaxExemptBondsInd
Escrow Account	false	EscrowAccountInd
On Behalf Of Issuer	false	OnBehalfOfIssuerInd
Engaged In Excess Benefit Trans	false	EngagedInExcessBenefitTransInd
PY Excess Benefit Trans	false	PYExcessBenefitTransInd
Loan Outstanding	false	LoanOutstandingInd
Grant To Related Person	false	GrantToRelatedPersonInd
Business Rln With Org Mem	false	BusinessRlnWithOrgMemInd
Business Rln With Fam Mem	false	BusinessRlnWithFamMemInd
Business Rln With Officer Ent	false	BusinessRlnWithOfficerEntInd
Deductible Non Cash Contri	false	DeductibleNonCashContriInd
Deductible Art Contribution	false	DeductibleArtContributionInd
Terminate Operations	false	TerminateOperationsInd
Partial Liquidation	false	PartialLiquidationInd
Disregarded Entity	Yes (true)	DisregardedEntityInd
Related Entity	Yes (true)	RelatedEntityInd
Related Organization Ctrl Ent	Yes (true)	RelatedOrganizationCtrlEntInd
Transaction With Control Ent	Yes (true)	TransactionWithControlEntInd
Trnsfr Exmpt Non Chrtbl Rltd Org	false	TrnsfrExmptNonChrtblRltdOrgInd
Activities Conducted Prtshp	false	ActivitiesConductedPrtshpInd
Schedule O Required	Yes (true)	ScheduleORequiredInd
IRP Document	754	IRPDocumentCnt
IRP Document W2 G	0	IRPDocumentW2GCnt
Backup Wthld Compliance	Yes (true)	BackupWthldComplianceInd
Employee	3255	EmployeeCnt
Employment Tax Returns Filed	Yes (true)	EmploymentTaxReturnsFiledInd
Unrelated Bus Incm Over Limit	Yes (true)	UnrelatedBusIncmOverLimitInd
Form990 T Filed	Yes (true)	Form990TFiledInd
Foreign Financial Account	Yes (true)	ForeignFinancialAccountInd
Foreign Country	AS	ForeignCountryCd
Foreign Country	AU	ForeignCountryCd
Foreign Country	BD	ForeignCountryCd
Foreign Country	BR	ForeignCountryCd
Foreign Country	VI	ForeignCountryCd
Foreign Country	CA	ForeignCountryCd
Foreign Country	BE	ForeignCountryCd
Foreign Country	CJ	ForeignCountryCd
Foreign Country	CI	ForeignCountryCd
Foreign Country	CH	ForeignCountryCd
Foreign Country	CO	ForeignCountryCd
Foreign Country	EZ	ForeignCountryCd
Foreign Country	DA	ForeignCountryCd
Foreign Country	EG	ForeignCountryCd
Foreign Country	EN	ForeignCountryCd
Foreign Country	FI	ForeignCountryCd
Foreign Country	FR	ForeignCountryCd
Foreign Country	GM	ForeignCountryCd
Foreign Country	GK	ForeignCountryCd
Foreign Country	HU	ForeignCountryCd
Foreign Country	AR	ForeignCountryCd
Foreign Country	HK	ForeignCountryCd
Foreign Country	IN	ForeignCountryCd
Foreign Country	EI	ForeignCountryCd
Foreign Country	IS	ForeignCountryCd
Foreign Country	IT	ForeignCountryCd
Foreign Country	JA	ForeignCountryCd
Foreign Country	JE	ForeignCountryCd
Foreign Country	JO	ForeignCountryCd
Foreign Country	KS	ForeignCountryCd
Foreign Country	ID	ForeignCountryCd
Foreign Country	KE	ForeignCountryCd
Foreign Country	LU	ForeignCountryCd
Foreign Country	MY	ForeignCountryCd
Foreign Country	MP	ForeignCountryCd
Foreign Country	MX	ForeignCountryCd
Foreign Country	MO	ForeignCountryCd
Foreign Country	NL	ForeignCountryCd
Foreign Country	NZ	ForeignCountryCd
Foreign Country	NO	ForeignCountryCd
Foreign Country	PL	ForeignCountryCd
Foreign Country	PO	ForeignCountryCd
Foreign Country	PE	ForeignCountryCd
Foreign Country	RO	ForeignCountryCd
Foreign Country	RS	ForeignCountryCd
Foreign Country	SN	ForeignCountryCd
Foreign Country	SF	ForeignCountryCd
Foreign Country	SP	ForeignCountryCd
Foreign Country	CE	ForeignCountryCd
Foreign Country	SW	ForeignCountryCd
Foreign Country	SZ	ForeignCountryCd
Foreign Country	TH	ForeignCountryCd
Foreign Country	TU	ForeignCountryCd
Foreign Country	AE	ForeignCountryCd
Foreign Country	UK	ForeignCountryCd
Foreign Country	UY	ForeignCountryCd
Foreign Country	ZI	ForeignCountryCd
Foreign Country	UC	ForeignCountryCd
Prohibited Tax Shelter Trans	false	ProhibitedTaxShelterTransInd
Taxable Party Notification	false	TaxablePartyNotificationInd
Nondeductible Contributions	false	NondeductibleContributionsInd
Quid Pro Quo Contributions	false	QuidProQuoContributionsInd
Form8282 Property Disposed Of	false	Form8282PropertyDisposedOfInd
Rcv Fnds To Pay Prsnl Bnft Cntrct	false	RcvFndsToPayPrsnlBnftCntrctInd
Pay Premiums Prsnl Bnft Cntrct	false	PayPremiumsPrsnlBnftCntrctInd
Indoor Tanning Services	false	IndoorTanningServicesInd
Info In Schedule O Part VI	Yes (X)	InfoInScheduleOPartVIInd
Governing Body Voting Members	10	GoverningBodyVotingMembersCnt
Independent Voting Member	10	IndependentVotingMemberCnt
Family Or Business Rln	false	FamilyOrBusinessRlnInd
Delegation Of Mgmt Duties	false	DelegationOfMgmtDutiesInd
Change To Org Documents	false	ChangeToOrgDocumentsInd
Material Diversion Or Misuse	false	MaterialDiversionOrMisuseInd
Members Or Stockholders	false	MembersOrStockholdersInd
Election Of Board Members	false	ElectionOfBoardMembersInd
Decisions Subject To Approva	false	DecisionsSubjectToApprovaInd
Minutes Of Governing Body	Yes (true)	MinutesOfGoverningBodyInd
Minutes Of Committees	Yes (true)	MinutesOfCommitteesInd
Officer Mailing Address	false	OfficerMailingAddressInd
Local Chapters	false	LocalChaptersInd
Form990 Provided To Gvrn Body	Yes (true)	Form990ProvidedToGvrnBodyInd
Conflict Of Interest Policy	Yes (true)	ConflictOfInterestPolicyInd
Annual Disclosure Covered Prsn	Yes (true)	AnnualDisclosureCoveredPrsnInd
Regular Monitoring Enfrc	Yes (true)	RegularMonitoringEnfrcInd
Whistleblower Policy	Yes (true)	WhistleblowerPolicyInd
Document Retention Policy	Yes (true)	DocumentRetentionPolicyInd
Compensation Process CEO	Yes (true)	CompensationProcessCEOInd
Compensation Process Other	Yes (true)	CompensationProcessOtherInd
Investment In Joint Venture	false	InvestmentInJointVentureInd
States Where Copy Of Return Is Fld	AK	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	AZ	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	CA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	IL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MD	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NY	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OK	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OR	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	IN	StatesWhereCopyOfReturnIsFldCd
Upon Request	Yes (X)	UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	MONIQUE L MARCUS	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Phone	3012158500	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	4000 JONES BRIDGE ROAD	AddressLine1Txt
City	CHEVY CHASE	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20815	ZIPCd

Form990 Part VII Section A Form990PartVIISectionAGrp (34 entries)

TitleTitleTxt	Average Hours Per WeekAverageHoursPerWeekRt	Individual Trustee Or DirectorIndividualTrusteeOrDirectorInd	Reportable Comp From OrgReportableCompFromOrgAmt	Reportable Comp From Rltd OrgReportableCompFromRltdOrgAmt	Other CompensationOtherCompensationAmt	OfficerOfficerInd	Key EmployeeKeyEmployeeInd	Highest Compensated EmployeeHighestCompensatedEmployeeInd	Former Ofcr Director TrusteeFormerOfcrDirectorTrusteeInd
JAMES A BAKER III ESQ
TRUSTEE	2.0	Yes (X)	$40,000	$0	$0
CHARLENE BARSHEFSKY ESQ
TRUSTEE	2.0	Yes (X)	$40,000	$0	$0
JOSEPH L GOLDSTEIN MD
TRUSTEE, CHAIRMAN RESEARCH COMM	4.0	Yes (X)	$48,000	$0	$0
FRED R LUMMIS
TRUSTEE, CHAIRMAN FINANCE COMM	4.0	Yes (X)	$50,000	$0	$0
PAUL M NURSE PHD
TRUSTEE	2.0	Yes (X)	$40,000	$0	$0
ALISON F RICHARD PHD
TRUSTEE, CHAIRMAN EDUCATION COMM	4.0	Yes (X)	$50,000	$0	$0
CLAYTON S ROSE PHD
TRUSTEE, CHAIRMAN AUDIT & COMP	6.0	Yes (X)	$50,000	$0	$0
KURT L SCHMOKE ESQ
TRUSTEE, CHAIRMAN	6.0	Yes (X)	$60,000	$0	$0
DEBORAH L SPAR PHD
TRUSTEE	2.0	Yes (X)	$33,911	$0	$0
ANNE M TATLOCK
TRUSTEE	2.0	Yes (X)	$40,000	$0	$0
ERIN K O'SHEA PHD
PRESIDENT	40.0		$831,324	$0	$45,716	Yes (X)
DENNIS MCKEARIN PHD
VP OF OPERATIONS	40.0		$618,252	$0	$98,759	Yes (X)
SEAN B CARROLL PHD
VP FOR SCIENCE EDUCATION	40.0		$702,062	$0	$52,549	Yes (X)
HEIDI E HENNING ESQ
VP,GENERAL COUNSEL/SEC	40.0		$588,945	$0	$56,526	Yes (X)
DAVID CLAPHAM PHD
VP & CHIEF SCI OFF	40.0		$506,885	$0	$54,464	Yes (X)
GERALD M RUBIN PHD
VP&EXEC DIR,JANELIA RES CAMPUS	40.0		$773,105	$0	$114,626	Yes (X)
LANDIS ZIMMERMAN
VP & CHIEF INVESTMENT OFFICER	40.0		$2,943,434	$0	$56,307	Yes (X)
NITIN V KOTAK
CFO & TREASURER thru 6/17	40.0		$411,844	$0	$52,709	Yes (X)
LAUREN T SPILIOTES ESQ
DEP GENCOUNSEL/ASST SEC	40.0		$403,384	$0	$55,496	Yes (X)
SUSAN S PLOTNICK
ASSISTANT TREASURER & DIRECTOR-FINANCE	40.0		$242,544	$0	$56,211	Yes (X)
MONIQUE L MARCUS
CONTROLLER	40.0		$197,419	$0	$47,863	Yes (X)
RICHARD A PENDER
MAN DIR - US EQUITIES	40.0		$1,024,984	$0	$53,643		Yes (X)
GREGORY DENINNO
MAN DIR - PRIVATE EQUITIES	40.0		$451,846	$0	$59,943		Yes (X)
ROBERT J KOLYER JR
MAN DIR - DIVERSIFIED ASSETS	40.0		$1,379,765	$0	$53,381		Yes (X)
STEPHEN M KITSOULIS
MAN DIR - FIXED INCOME	40.0		$784,355	$0	$46,813		Yes (X)
MARK A BARNARD
MAN DIR - PRIVATE EQUITIES thru 6/16	40.0		$689,350	$0	$32,021		Yes (X)
DONALD KOCH
MAN DIR - PORTFOLIO STRATEGY	40.0		$1,052,044	$0	$54,365			Yes (X)
ANIL MADHOK
MAN DIR - INVESTMENTS & COO	40.0		$958,364	$0	$41,739			Yes (X)
THOMAS R CECH PHD
INVESTIGATOR	40.0		$655,133	$0	$47,933			Yes (X)
ERIC R KANDEL MD
SENIOR INVESTIGATOR	40.0		$615,568	$0	$59,965			Yes (X)
ROBERT TJIAN PHD
PRESIDENT thru 8/16	40.0		$1,294,848	$0	$61,563			Yes (X)
CHERYL A MOORE
EXECUTIVE VP & COO thru 1/16	40.0		$129,023	$0	$3,659				Yes (X)
JOHN PALMISANO
VP FOR INFORMATION TECHNOLOGY thru 8/16	40.0		$286,424	$0	$35,335				Yes (X)
KATHY WYSZYNSKI
VP, HUMAN RESOURCES thru 8/16	40.0		$282,175	$0	$40,923				Yes (X)

Field	Value	IRS element (for citing)
Total Reportable Comp From Org	$18,274,988	TotalReportableCompFromOrgAmt
Tot Reportable Comp Rltd Org	$0	TotReportableCompRltdOrgAmt
Total Other Compensation	$1,282,509	TotalOtherCompensationAmt
Indiv Rcvd Greater Than100 K	711	IndivRcvdGreaterThan100KCnt
Former Ofcr Employees Listed	Yes (true)	FormerOfcrEmployeesListedInd
Total Comp Greater Than150 K	Yes (true)	TotalCompGreaterThan150KInd
Compensation From Other Srcs	Yes (true)	CompensationFromOtherSrcsInd

Contractor Compensation ContractorCompensationGrp (5 entries)

Address Line1ContractorAddress/USAddress/AddressLine1Txt	CityContractorAddress/USAddress/CityNm	State AbbreviationContractorAddress/USAddress/StateAbbreviationCd	ZIPContractorAddress/USAddress/ZIPCd	ServicesServicesDesc	CompensationCompensationAmt	Address Line2ContractorAddress/USAddress/AddressLine2Txt
ARAMARK HARRISON LODGING
1101 MARKET ST	PHILADELPHIA	PA	19107	CONFERENCE CTR MGT	$4,241,380
SELECT EQUITY GROUP INC
380 LAFEYETTE STREET	NEW YORK	NY	10003	INVESTMENT MGT	$3,377,853
CHARLES RIVER LABS INC
251 BALLARADVALE STREET	WILMINGTON	MA	01887	RESEARCH SERVICES	$2,959,367
JONES LANG LASALLE AMERICAS INC
525 WILLIAM PENN PLACE	PITTSBURGH	PA	15259	FACILITIES MGT	$2,737,201	SUITE 2500
GOLDEN GATE CAPITAL
ONE EMBARCADERO CENTER	SAN FRANCISCO	CA	94111	INVESTMENT MGT	$2,634,722	39TH FLOOR

Field	Value	IRS element (for citing)
Cntrct Rcvd Greater Than100 K	156	CntrctRcvdGreaterThan100KCnt
Info In Schedule O Part VIII	Yes (X)	InfoInScheduleOPartVIIIInd
All Other Contributions	$961,418	AllOtherContributionsAmt
Total Contributions	$961,418	TotalContributionsAmt

Program Service Revenue ProgramServiceRevenueGrp (2 entries)

DescDesc	BusinessBusinessCd	Total Revenue ColumnTotalRevenueColumnAmt	Related Or Exempt Func IncomeRelatedOrExemptFuncIncomeAmt
RENTAL INCOME	900099	$2,552,736	$2,552,736
TV & Film Income	900099	$40,506	$40,506

Total Oth Program Service Rev TotalOthProgramServiceRevGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$0	TotalRevenueColumnAmt
Related Or Exempt Func Income	$0	RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue	$0	UnrelatedBusinessRevenueAmt
Exclusion	$0	ExclusionAmt

Field	Value	IRS element (for citing)
Total Program Service Revenue	$2,593,242	TotalProgramServiceRevenueAmt

Investment Income InvestmentIncomeGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$192,721,183	TotalRevenueColumnAmt
Unrelated Business Revenue	$20,486,398	UnrelatedBusinessRevenueAmt
Exclusion	$172,234,785	ExclusionAmt

Royalties Revenue RoyaltiesRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$21,446,583	TotalRevenueColumnAmt
Exclusion	$21,446,583	ExclusionAmt

Gross Rents GrossRentsGrp

Field	Value	IRS element (for citing)
Real	$696,011	RealAmt

Less Rental Expenses LessRentalExpensesGrp

Field	Value	IRS element (for citing)
Real	$1,517,914	RealAmt

Rental Income Or Loss RentalIncomeOrLossGrp

Field	Value	IRS element (for citing)
Real	-$821,903	RealAmt
Personal	$0	PersonalAmt

Net Rental Income Or Loss NetRentalIncomeOrLossGrp

Field	Value	IRS element (for citing)
Total Revenue Column	-$821,903	TotalRevenueColumnAmt
Unrelated Business Revenue	-$801,320	UnrelatedBusinessRevenueAmt
Exclusion	-$20,583	ExclusionAmt

Gross Amount Sales Assets GrossAmountSalesAssetsGrp

Field	Value	IRS element (for citing)
Securities	$48,247,896,027	SecuritiesAmt

Less Cost Oth Basis Sales Expnss LessCostOthBasisSalesExpnssGrp

Field	Value	IRS element (for citing)
Securities	$46,915,011,496	SecuritiesAmt

Gain Or Loss GainOrLossGrp

Field	Value	IRS element (for citing)
Securities	$1,332,884,531	SecuritiesAmt
Other	$0	OtherAmt

Net Gain Or Loss Investments NetGainOrLossInvestmentsGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$1,332,884,531	TotalRevenueColumnAmt
Exclusion	$1,332,884,531	ExclusionAmt

Other Revenue Misc OtherRevenueMiscGrp (3 entries)

DescDesc	BusinessBusinessCd	Total Revenue ColumnTotalRevenueColumnAmt	ExclusionExclusionAmt
CAFETERIA INCOME	900099	$293,881	$293,881
INVESTMENT EXPENSE REBATE	900099	$155,161	$155,161
CASH DISCOUNTS	900099	$120,983	$120,983

Miscellaneous Revenue MiscellaneousRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$192,812	TotalRevenueColumnAmt
Related Or Exempt Func Income	$0	RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue	$0	UnrelatedBusinessRevenueAmt
Exclusion	$192,812	ExclusionAmt

Field	Value	IRS element (for citing)
Other Revenue Total	$762,837	OtherRevenueTotalAmt

Total Revenue TotalRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$1,550,547,891	TotalRevenueColumnAmt
Related Or Exempt Func Income	$2,593,242	RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue	$19,685,078	UnrelatedBusinessRevenueAmt
Exclusion	$1,527,308,153	ExclusionAmt

Grants To Domestic Orgs GrantsToDomesticOrgsGrp

Field	Value	IRS element (for citing)
Total	$51,079,820	TotalAmt
Program Services	$51,079,820	ProgramServicesAmt

Grants To Domestic Individuals GrantsToDomesticIndividualsGrp

Field	Value	IRS element (for citing)
Total	$8,803,923	TotalAmt
Program Services	$8,803,923	ProgramServicesAmt

Foreign Grants ForeignGrantsGrp

Field	Value	IRS element (for citing)
Total	$34,875,000	TotalAmt
Program Services	$34,875,000	ProgramServicesAmt

Comp Current Ofcr Directors CompCurrentOfcrDirectorsGrp

Field	Value	IRS element (for citing)
Total	$10,536,023	TotalAmt
Program Services	$2,591,102	ProgramServicesAmt
Management And General	$7,944,921	ManagementAndGeneralAmt

Comp Disqual Persons CompDisqualPersonsGrp

Field	Value	IRS element (for citing)
Total	$1,592,293	TotalAmt
Management And General	$1,592,293	ManagementAndGeneralAmt

Other Salaries And Wages OtherSalariesAndWagesGrp

Field	Value	IRS element (for citing)
Total	$265,167,113	TotalAmt
Program Services	$228,057,145	ProgramServicesAmt
Management And General	$37,109,968	ManagementAndGeneralAmt

Pension Plan Contributions PensionPlanContributionsGrp

Field	Value	IRS element (for citing)
Total	$22,292,801	TotalAmt
Program Services	$19,142,119	ProgramServicesAmt
Management And General	$3,150,682	ManagementAndGeneralAmt

Other Employee Benefits OtherEmployeeBenefitsGrp

Field	Value	IRS element (for citing)
Total	$88,149,078	TotalAmt
Program Services	$74,945,558	ProgramServicesAmt
Management And General	$13,203,520	ManagementAndGeneralAmt

Payroll Taxes PayrollTaxesGrp

Field	Value	IRS element (for citing)
Total	$17,283,925	TotalAmt
Program Services	$14,595,234	ProgramServicesAmt
Management And General	$2,688,691	ManagementAndGeneralAmt

Fees For Services Legal FeesForServicesLegalGrp

Field	Value	IRS element (for citing)
Total	$3,452,762	TotalAmt
Program Services	$1,590,278	ProgramServicesAmt
Management And General	$1,862,484	ManagementAndGeneralAmt

Fees For Services Accounting FeesForServicesAccountingGrp

Field	Value	IRS element (for citing)
Total	$959,641	TotalAmt
Program Services	$8,166	ProgramServicesAmt
Management And General	$951,475	ManagementAndGeneralAmt

Fees For Services Lobbying FeesForServicesLobbyingGrp

Field	Value	IRS element (for citing)
Total	$15,000	TotalAmt
Management And General	$15,000	ManagementAndGeneralAmt

Fees For Srvc Invst Mgmnt Fees FeesForSrvcInvstMgmntFeesGrp

Field	Value	IRS element (for citing)
Total	$69,931,386	TotalAmt
Management And General	$69,931,386	ManagementAndGeneralAmt

Fees For Services Other FeesForServicesOtherGrp

Field	Value	IRS element (for citing)
Total	$44,488,346	TotalAmt
Program Services	$28,646,161	ProgramServicesAmt
Management And General	$15,842,185	ManagementAndGeneralAmt
Fundraising	$0	FundraisingAmt

Office Expenses OfficeExpensesGrp

Field	Value	IRS element (for citing)
Total	$3,821,547	TotalAmt
Program Services	$2,801,374	ProgramServicesAmt
Management And General	$1,020,173	ManagementAndGeneralAmt

Information Technology InformationTechnologyGrp

Field	Value	IRS element (for citing)
Total	$8,021,641	TotalAmt
Program Services	$981,939	ProgramServicesAmt
Management And General	$7,039,702	ManagementAndGeneralAmt

Royalties RoyaltiesGrp

Field	Value	IRS element (for citing)
Total	$5,331	TotalAmt
Program Services	$4,431	ProgramServicesAmt
Management And General	$900	ManagementAndGeneralAmt

Occupancy OccupancyGrp

Field	Value	IRS element (for citing)
Total	$74,004,149	TotalAmt
Program Services	$68,415,394	ProgramServicesAmt
Management And General	$5,588,755	ManagementAndGeneralAmt

Travel TravelGrp

Field	Value	IRS element (for citing)
Total	$8,071,498	TotalAmt
Program Services	$6,448,905	ProgramServicesAmt
Management And General	$1,622,593	ManagementAndGeneralAmt

Conferences Meetings ConferencesMeetingsGrp

Field	Value	IRS element (for citing)
Total	$3,216,060	TotalAmt
Program Services	$2,537,925	ProgramServicesAmt
Management And General	$678,135	ManagementAndGeneralAmt

Interest InterestGrp

Field	Value	IRS element (for citing)
Total	$78,550,828	TotalAmt
Program Services	$309,496	ProgramServicesAmt
Management And General	$78,241,332	ManagementAndGeneralAmt

Depreciation Depletion DepreciationDepletionGrp

Field	Value	IRS element (for citing)
Total	$80,354,035	TotalAmt
Program Services	$71,941,589	ProgramServicesAmt
Management And General	$8,412,446	ManagementAndGeneralAmt

Insurance InsuranceGrp

Field	Value	IRS element (for citing)
Total	$396,982	TotalAmt
Program Services	$73,268	ProgramServicesAmt
Management And General	$323,714	ManagementAndGeneralAmt

Other Expenses OtherExpensesGrp (4 entries)

DescDesc	TotalTotalAmt	Program ServicesProgramServicesAmt	Management And GeneralManagementAndGeneralAmt
LAB & OTHER SCIENTIFIC SUPPLIES	$126,394,492	$125,199,931	$1,194,561
MINOR EQUIPMENT & RENOVATIONS	$16,959,235	$16,814,515	$144,720
EQUIPMENT MAINTENANCE	$14,893,026	$13,899,351	$993,675
Income Tax	$821,185		$821,185

All Other Expenses AllOtherExpensesGrp

Field	Value	IRS element (for citing)
Total	$9,316,801	TotalAmt
Program Services	$9,505,625	ProgramServicesAmt
Management And General	-$188,824	ManagementAndGeneralAmt
Fundraising	$0	FundraisingAmt

Total Functional Expenses TotalFunctionalExpensesGrp

Field	Value	IRS element (for citing)
Total	$1,043,453,921	TotalAmt
Program Services	$783,268,249	ProgramServicesAmt
Management And General	$260,185,672	ManagementAndGeneralAmt
Fundraising	$0	FundraisingAmt

Savings And Temp Cash Invst SavingsAndTempCashInvstGrp

Field	Value	IRS element (for citing)
BOY	$331,496,720	BOYAmt
EOY	$313,788,984	EOYAmt

Receivables From Officers Etc ReceivablesFromOfficersEtcGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt
EOY	$0	EOYAmt

Rcvbl From Disqualified Prsn RcvblFromDisqualifiedPrsnGrp

Field	Value	IRS element (for citing)
EOY	$0	EOYAmt

Prepaid Expenses Defrd Charges PrepaidExpensesDefrdChargesGrp

Field	Value	IRS element (for citing)
BOY	$10,034,921	BOYAmt
EOY	$10,916,217	EOYAmt

Field	Value	IRS element (for citing)
Land Bldg Equip Cost Or Other Bss	$1,781,885,694	LandBldgEquipCostOrOtherBssAmt
Land Bldg Equip Accum Deprec	$1,069,964,696	LandBldgEquipAccumDeprecAmt

Land Bldg Equip Basis Net LandBldgEquipBasisNetGrp

Field	Value	IRS element (for citing)
BOY	$738,818,110	BOYAmt
EOY	$711,920,998	EOYAmt

Investments Pub Traded Sec InvestmentsPubTradedSecGrp

Field	Value	IRS element (for citing)
BOY	$6,611,550,109	BOYAmt
EOY	$7,234,725,303	EOYAmt

Investments Other Securities InvestmentsOtherSecuritiesGrp

Field	Value	IRS element (for citing)
BOY	$13,078,172,731	BOYAmt
EOY	$14,044,326,015	EOYAmt

Investments Program Related InvestmentsProgramRelatedGrp

Field	Value	IRS element (for citing)
BOY	$0	BOYAmt

Other Assets Total OtherAssetsTotalGrp

Field	Value	IRS element (for citing)
BOY	$312,429,699	BOYAmt
EOY	$278,738,241	EOYAmt

Total Assets TotalAssetsGrp

Field	Value	IRS element (for citing)
BOY	$21,082,502,290	BOYAmt
EOY	$22,594,415,758	EOYAmt

Accounts Payable Accr Expnss AccountsPayableAccrExpnssGrp

Field	Value	IRS element (for citing)
BOY	$555,985,053	BOYAmt
EOY	$503,181,931	EOYAmt

Grants Payable GrantsPayableGrp

Field	Value	IRS element (for citing)
BOY	$161,167,676	BOYAmt
EOY	$173,350,134	EOYAmt

Tax Exempt Bond Liabilities TaxExemptBondLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$716,130,000	BOYAmt
EOY	$716,130,000	EOYAmt

Unsecured Notes Loans Payable UnsecuredNotesLoansPayableGrp

Field	Value	IRS element (for citing)
BOY	$1,234,673,954	BOYAmt
EOY	$1,235,453,517	EOYAmt

Other Liabilities OtherLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$638,986,054	BOYAmt
EOY	$657,102,151	EOYAmt

Total Liabilities TotalLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$3,306,942,737	BOYAmt
EOY	$3,285,217,733	EOYAmt

Field	Value	IRS element (for citing)
Organization Follows SFAS117	Yes (X)	OrganizationFollowsSFAS117Ind

Unrestricted Net Assets UnrestrictedNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$17,775,559,553	BOYAmt
EOY	$19,309,198,025	EOYAmt

Total Net Assets Fund Balance TotalNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$17,775,559,553	BOYAmt
EOY	$19,309,198,025	EOYAmt

Tot Liab Net Assets Fund Balance TotLiabNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$21,082,502,290	BOYAmt
EOY	$22,594,415,758	EOYAmt

Field	Value	IRS element (for citing)
Info In Schedule O Part XI	Yes (X)	InfoInScheduleOPartXIInd
Reconcilation Revenue Expnss	$507,093,970	ReconcilationRevenueExpnssAmt
Net Unrlzd Gains Losses Invst	$934,015,853	NetUnrlzdGainsLossesInvstAmt
Other Changes In Net Assets	$92,528,649	OtherChangesInNetAssetsAmt
Method Of Accounting Accrual	Yes (X)	MethodOfAccountingAccrualInd
Accountant Compile Or Review	false	AccountantCompileOrReviewInd
FS Audited	Yes (true)	FSAuditedInd

FS Audited Basis FSAuditedBasisGrp

Field	Value	IRS element (for citing)
Consolidated Basis Fincl Stmt	Yes (X)	ConsolidatedBasisFinclStmtInd

Field	Value	IRS element (for citing)
Audit Committee	Yes (true)	AuditCommitteeInd
Federal Grant Audit Required	false	FederalGrantAuditRequiredInd

Schedule A IRS990ScheduleA

Field	Value	IRS element (for citing)
Medical Research Organization	Yes (X)	MedicalResearchOrganizationInd

Hospital Name And Address HospitalNameAndAddressGrp

Supported Organization Name SupportedOrganizationName

Field	Value	IRS element (for citing)
Business Name Line1	Brigham and Womens Hospital	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
City	Boston	CityNm
State Abbreviation	MA	StateAbbreviationCd

Schedule B IRS990ScheduleB

Contributor Information ContributorInformationGrp

Field	Value	IRS element (for citing)
Contributor	RESTRICTED	ContributorNum

Contributor Business Name ContributorBusinessName

Field	Value	IRS element (for citing)
Business Name Line1	RESTRICTED	BusinessNameLine1

Contributor US Address ContributorUSAddress

Field	Value	IRS element (for citing)
Address Line1	RESTRICTED	AddressLine1
Address Line2	RESTRICTED	AddressLine2
City	RESTRICTED	City
State	RESTRICTED	State
ZIP Code	RESTRICTED	ZIPCode

Field	Value	IRS element (for citing)
Total Contributions	RESTRICTED	TotalContributionsAmt

Schedule C IRS990ScheduleC

Field	Value	IRS element (for citing)
Volunteers	false	VolunteersInd
Paid Staff Or Management	false	PaidStaffOrManagementInd
Media Advertisements	false	MediaAdvertisementsInd
Mailings Members	false	MailingsMembersInd
Publications Or Broadcast	false	PublicationsOrBroadcastInd
Grants Other Organizations	false	GrantsOtherOrganizationsInd
Direct Contact Legislators	Yes (true)	DirectContactLegislatorsInd
Direct Contact Legislators	$15,000	DirectContactLegislatorsAmt
Rallies Demonstrations	false	RalliesDemonstrationsInd
Other Activities	Yes (true)	OtherActivitiesInd
Other Activities	$1,529	OtherActivitiesAmt
Total Lobbying Expenditures	$16,529	TotalLobbyingExpendituresAmt
Not Described Section501c3	false	NotDescribedSection501c3Ind

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDesc

ExplanationExplanationTxt

Schedule C, Part II-B, Line 1 DETAILED DESCRIPTION OF THE LOBBYING ACTIVITY

OTHER ACTIVITIES, SCHEDULE C, PART II-B, LINE 1g (OTHER ACTIVITIES) Amounts spent to paid lobbying firm for direct contact with federal legislators and their staffs on pending legislative matters. OTHER ACTIVITIES, SCHEDULE C, PART II-B, LINE 1I (OTHER ACTIVITIES) DURING THE FISCAL YEAR, HHMI WAS A MEMBER OF A NUMBER OF NON-PROFIT ORGANIZATIONS THAT ENGAGED IN LOBBYING ACTIVITIES ON BEHALF OF THEIR MEMBERSHIPS. HHMI IS REPORTING AS LOBBYING EXPENDITURES A PORTION OF THE MEMBERSHIP DUES THAT HHMI PAID TO THESE ORGANIZATIONS.

Schedule C, Part II-B, Line 1 DETAILED DESCRIPTION OF THE LOBBYING ACTIVITY

Schedule D IRS990ScheduleD

Land LandGrp

Field	Value	IRS element (for citing)
Investment Cost Or Other Basis	$807,737	InvestmentCostOrOtherBasisAmt
Other Cost Or Other Basis	$84,964,142	OtherCostOrOtherBasisAmt
Book Value	$85,771,879	BookValueAmt

Buildings BuildingsGrp

Field	Value	IRS element (for citing)
Investment Cost Or Other Basis	$10,248,413	InvestmentCostOrOtherBasisAmt
Other Cost Or Other Basis	$754,831,405	OtherCostOrOtherBasisAmt
Depreciation	$296,137,655	DepreciationAmt
Book Value	$468,942,163	BookValueAmt

Leasehold Improvements LeaseholdImprovementsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$362,328,370	OtherCostOrOtherBasisAmt
Depreciation	$339,158,083	DepreciationAmt
Book Value	$23,170,287	BookValueAmt

Equipment EquipmentGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$535,533,028	OtherCostOrOtherBasisAmt
Depreciation	$427,155,384	DepreciationAmt
Book Value	$108,377,644	BookValueAmt

Other Land Buildings OtherLandBuildingsGrp

Field	Value	IRS element (for citing)
Investment Cost Or Other Basis	$921,448	InvestmentCostOrOtherBasisAmt
Other Cost Or Other Basis	$32,251,151	OtherCostOrOtherBasisAmt
Depreciation	$7,513,574	DepreciationAmt
Book Value	$25,659,025	BookValueAmt

Field	Value	IRS element (for citing)
Total Book Value Land Buildings	$711,920,998	TotalBookValueLandBuildingsAmt

Other Securities OtherSecuritiesGrp (5 entries)

DescDesc	Book ValueBookValueAmt	Method ValuationMethodValuationCd
PRIVATE EQUITY & REAL ESTATE	$5,111,939,362	F
DISTRESSED & CREDIT SENSITIVE	$2,346,503,266	F
HEDGED EQUITY	$2,271,749,523	F
MARKET NEUTRAL	$1,680,540,584	F
EQUITY COMMINGLED	$2,633,593,280	F

Field	Value	IRS element (for citing)
Total Book Value Securities	$14,044,326,015	TotalBookValueSecuritiesAmt

Other Liabilities Org OtherLiabilitiesOrgGrp (11 entries)

DescDesc	AmtAmt
DERIVATIVE LIABILITIES
SHORT POSITIONS	$383,977,061
INVESTMENT PURCH PENDING SALES	$62,445,239
CURRENCY EXCH CONTRACTS PAY	$1,796,543
PAY REALIZED GAINS ON FUTURES
DEFERRED COMPENSATION LIAB	$44,712,169
SWAP UNREALIZED LOSS	$148,892,160
INVESTMENT MANAGEMENT FEES PAYABLE	$7,062,641
DEFERRED INCOME	$1,811,590
INTEREST & DIVIDENDS ON SHORT STOCKS & BONDS	$640,554
CONTRACT FOR DIFFERENCES LIABILITY	$5,764,194

Field	Value	IRS element (for citing)
Total Liability	$657,102,151	TotalLiabilityAmt
Total Rev Etc Audited Fincl Stmt	$2,382,777,960	TotalRevEtcAuditedFinclStmtAmt
Net Unrealized Gains Invst	$934,015,853	NetUnrealizedGainsInvstAmt
Other Revenue	$0	OtherRevenueAmt
Revenue Not Reported	$934,015,853	RevenueNotReportedAmt
Revenue Subtotal	$1,448,762,107	RevenueSubtotalAmt
Investment Expenses Not Incld	$103,303,698	InvestmentExpensesNotIncldAmt
Other Revenues Not Included	-$1,517,914	OtherRevenuesNotIncludedAmt
Revenue Not Reported Fincl Stmt	$101,785,784	RevenueNotReportedFinclStmtAmt
Total Revenue Per Form990	$1,550,547,891	TotalRevenuePerForm990Amt
Tot Expns Etc Audited Fincl Stmt	$936,514,488	TotExpnsEtcAuditedFinclStmtAmt
Other Expenses Included	$0	OtherExpensesIncludedAmt
Expenses Not Reported	$0	ExpensesNotReportedAmt
Expenses Subtotal	$936,514,488	ExpensesSubtotalAmt
Investment Expenses Not Incld2	$103,303,698	InvestmentExpensesNotIncld2Amt
Other Expenses Not Included	$3,635,735	OtherExpensesNotIncludedAmt
Expenses Not Rpt Fincl Stmt	$106,939,433	ExpensesNotRptFinclStmtAmt
Total Expenses Per Form990	$1,043,453,921	TotalExpensesPerForm990Amt

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
Schedule D, Part XI, Line 4(b) Other revenues in form 990 not in audited financial statements	Rental Expenses - -1517914
Schedule D, Part XII, Line 4(b) Other expenses in form 990 not in audited financial statements	Rental Expenses - -1517914 Grants refunds, write-offs etc. - 5153649

Schedule F IRS990ScheduleF

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (true)	GrantRecordsMaintainedInd

Account Activities Outside US AccountActivitiesOutsideUSGrp (16 entries)

RegionRegionTxt	Type Of Activities ConductedTypeOfActivitiesConductedTxt	Region Total ExpendituresRegionTotalExpendituresAmt	Specific Services ProvidedSpecificServicesProvidedTxt
Central America and the Caribbean	Investments	$7,278,535,754
North America (Canada & Mexico only)	Investments	$189,356,445
Europe (Including Iceland and Greenland)	Investments	$1,384,284,104
East Asia and the Pacific	Investments	$599,713,335
South America	Investments	$50,628,290
South Asia	Investments	$47,838,272
Middle East and North Africa	Investments	$9,894,925
Russia and Neighboring States	Investments	$683,463
Sub-Saharan Africa	Investments	$38,821,976
East Asia and the Pacific	Grantmaking	$5,720,000
Europe (Including Iceland and Greenland)	Grantmaking	$5,720,000
Middle East and North Africa	Grantmaking	$2,860,000
South America	Grantmaking	$2,145,000
South Asia	Grantmaking	$715,000
Sub-Saharan Africa	Grantmaking	$17,715,000
Europe (Including Iceland and Greenland)	Program Services	$3,052,102	Open Access

Field	Value	IRS element (for citing)
Subtotal Offices	0	SubtotalOfficesCnt
Subtotal Employees	0	SubtotalEmployeesCnt
Continutation Total Office	0	ContinutationTotalOfficeCnt
Continutation Total Employee	0	ContinutationTotalEmployeeCnt
Total Office	0	TotalOfficeCnt
Total Employee	0	TotalEmployeeCnt
Subtotal Spent	$9,637,683,666	SubtotalSpentAmt
Continuation Spent	$0	ContinuationSpentAmt
Total Spent	$9,637,683,666	TotalSpentAmt

Grants To Org Outside US GrantsToOrgOutsideUSGrp (22 entries)

RegionRegionTxt	Purpose Of GrantPurposeOfGrantTxt	Cash GrantCashGrantAmt	Manner Of Cash DisbursementMannerOfCashDisbursementTxt
Sub-Saharan Africa	Medical Research	$17,000,000	WT
Sub-Saharan Africa	Medical Research	$715,000	WT
East Asia and the Pacific	Medical Research	$715,000	WT
East Asia and the Pacific	Medical Research	$715,000	WT
East Asia and the Pacific	Medical Research	$1,430,000	WT
East Asia and the Pacific	Medical Research	$715,000	WT
East Asia and the Pacific	Medical Research	$715,000	WT
East Asia and the Pacific	Medical Research	$715,000	WT
East Asia and the Pacific	Medical Research	$715,000	WT
Europe (Including Iceland and Greenland)	Medical Research	$715,000	WT
Europe (Including Iceland and Greenland)	Medical Research	$715,000	WT
Europe (Including Iceland and Greenland)	Medical Research	$715,000	WT
Europe (Including Iceland and Greenland)	Medical Research	$1,430,000	WT
Europe (Including Iceland and Greenland)	Medical Research	$715,000	WT
Europe (Including Iceland and Greenland)	Medical Research	$715,000	WT
Europe (Including Iceland and Greenland)	Medical Research	$715,000	WT
Middle East and North Africa	Medical Research	$1,430,000	WT
Middle East and North Africa	Medical Research	$1,430,000	WT
South America	Medical Research	$715,000	WT
South America	Medical Research	$715,000	WT
South America	Medical Research	$715,000	WT
South Asia	Medical Research	$715,000	WT

Field	Value	IRS element (for citing)
Total501c3 Org	3	Total501c3OrgCnt
Total Other Org	18	TotalOtherOrgCnt
Transfer To Foreign Corp	Yes (true)	TransferToForeignCorpInd
Interest In Foreign Trust	Yes (true)	InterestInForeignTrustInd
Foreign Corp Ownership	Yes (true)	ForeignCorpOwnershipInd
Passive Foreign Investmest Co	Yes (true)	PassiveForeignInvestmestCoInd
Foreign Partnership	Yes (true)	ForeignPartnershipInd
Boycott Countries	false	BoycottCountriesInd

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDesc

ExplanationExplanationTxt

Schedule F, Part I, Line 2 Procedures for monitoring use of grant funds

During its 2017 fiscal year, HHMI continued to support International Research Scholars selected through one or more competitions open to all eligible applicants. Eligibility requirements included, but were not limited to, a full-time appointment at a nonprofit scientific research organization in a country other than the United States, and a research focus on basic biological processes or disease mechanisms. Qualified applicants were evaluated by a panel of scientific experts with final selections made by HHMI leadership. The disbursement of grant funds to support the work of International Early Career Scientists and Senior International Research Scholars is made in accordance with all applicable U.S. laws. Funds are paid to an institutional account. In order to monitor the activities and productivity of the grants, each scientist is required to submit an annual progress report concerning his or her research and each grantee institution is required to submit annual financial reports. These reports are reviewed by HHMI staff. site visits and audits are conducted if warranted and grantees attend scientific meetings of HHMI US-based scientists.

Schedule F, Part I, Line 2 PROCEDURES FOR MONITORING USE OF GRANT FUNDS

Schedule I IRS990ScheduleI

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (true)	GrantRecordsMaintainedInd

Recipient Table RecipientTable (88 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	Recipient EINRecipientEIN	IRC SectionIRCSectionDesc	Cash GrantCashGrantAmt	Non Cash AssistanceNonCashAssistanceAmt	Purpose Of GrantPurposeOfGrantTxt
UC - Santa Barbara
UC - Santa Barbara	Santa Barbara	CA	93106	956006145	501 (c) 3	$50,000	$0	Ugrad Science Ed
UC- Los Angeles
UC- Los Angeles	Los Angeles	CA	90095	956006143	501 (c) 3	$45,722	$0	Ugrad Science Ed
Univ of Washington
Univ of Washington	Seattle	WA	98195	916001537	501 (c) 3	$9,732	$0	Ugrad Science Ed
Univ Of Miami
Univ Of Miami	Coral Gables	FL	33146	590624458	501 (c) 3	$5,855	$0	Ugrad Science Ed
Univ Of Wisconsin
Univ Of Wisconsin	Madison	WI	53706	396006492	501 (c) 3	$30,587	$0	Ugrad Science Ed
Univ of Washington
Univ of Washington	Seattle	WA	98195	916001537	501 (c) 3	$55,000	$0	University (Doctoral)
Chaminade Univ
Chaminade Univ	Honolulu	HI	96816	990272261	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Delaware State Univ
Delaware State Univ	Dover	DE	19901	510305893	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Humboldt State Univ
Humboldt State Univ	Arcata	CA	95521	946050071	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Kenyon College
Kenyon College	Gambier	OH	43022	314379507	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Lawrence Technological Univ
Lawrence Technological Univ	Southfield	MI	48075	381369604	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Northeastern Univ
Northeastern Univ	Boston	MA	02115	041679980	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Oberlin College
Oberlin College	Oberlin	OH	44074	340714363	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Radford Univ
Radford Univ	Radford	VA	24141	546001789	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Rochester Institute of Technology
Rochester Inst of Technology	Rochester	NY	14623	160743140	501 (c) 3	$1,000,000	$0	Inclusive Excellence
San Francisco State Univ
San Francisco State Univ	San Francisco	CA	94132	931137247	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Stony Brook Univ
Stony Brook Univ	Stony Brook	NY	11794	141368361	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Towson Univ
Towson Univ	Towson	MD	21252	526002033	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Trinity Washington Univ
Trinity Washington Univ	Washington	DC	20017	530196640	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Tufts Univ
Tufts Univ	Boston	MA	02111	042103648	501 (c) 3	$1,000,000	$0	Inclusive Excellence
UC- Davis
UC- Davis	Davis	CA	95616	946036494	501 (c) 3	$1,000,000	$0	Inclusive Excellence
UC- Los Angeles
UC- Los Angeles	Los Angeles	CA	90095	956006143	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Univ of Colorado
Univ of Colorado	Denver	CO	80203	846000555	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Univ of Northern Colorado
Univ of Northern Colorado	Greeley	CO	80639	846000546	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Univ of South Dakota
Univ of South Dakota	Vermillion	SD	57069	466003541	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Univ of Texas Rio Grande Valley
UT Rio Grande Valley	Brownsville	TX	78520	465292740	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Univ of Utah
Univ of Utah	Salt Lake City	UT	84112	876000525	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Virginia Tech Univ
Virginia Tech Univ	Blacksburg	VA	24061	546001805	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Washington Univ
Washington Univ	St Louis	MO	63130	430653611	501 (c) 3	$1,000,000	$0	Inclusive Excellence
Western Washington Univ
Western Washington Univ	Bellingham	WA	98225	916000562	501 (c) 3	$1,000,000	$0	Inclusive Excellence
UC - San Francisco
UC - San Francisco	San Francisco	CA	94143	946036493	501 (c) 3	$24,812	$0	EXROP Program - Housing
Travel Expense paid on behalf of grantees-Calista Hotel
1485 Bush Street	San Francisco	CA	94109			$10,850	$0	EXROP Program - Housing
CA Inst of Technology
CA Inst of Technology	Pasadena	CA	91125	951643307	501 (c) 3	$5,157	$0	EXROP Program - Housing
Cornell Univ
Cornell Univ	Ithaca	NY	14853	150532082	501 (c) 3	$5,492	$0	EXROP Program - Housing
Univ of Washington
Univ of Washington	Seattle	WA	98195	916001537	501 (c) 3	$15,240	$0	EXROP Program - Housing
Travel Expense paid on behalf of grantees-AMR Corp
4333 Amon Carter Blvd	Fort Worth	TX	76155	751825172		$7,440	$0	EXROP Program - Travel
UC - Berkeley
UC - Berkeley	Berkeley	CA	94720	946002123	501 (c) 3	$23,595	$0	EXROP Program - Housing
Travel Expense paid on behalf of grantees-Southwest Air
PO Box 36611	Dallas	TX	75235	741563240		$5,497	$0	EXROP Program - Travel
Columbia University
Columbia University	New York	NY	10027	135598093	501 (c) 3	$19,000	$0	EXROP Program - Housing
Harvard University
Harvard University	Cambridge	MA	02138	042103580	501 (c) 3	$35,297	$0	EXROP Program - Housing
Yale University
Yale University	New Haven	CT	06520	060646973	501 (c) 3	$18,819	$0	EXROP Program - Housing
Travel Expense paid on behalf of grantees-La Jolla Cove Ste
1155 Coast Blvd	La Jolla	CA	92037	952099802		$6,259	$0	EXROP Program - Housing
Travel Expense paid on behalf of grantees-Longwood Inn
342 Longwood Avenue	Brookline	MA	02446	042932331		$10,347	$0	EXROP Program - Housing
Marine Biological Lab
Marine Biological Lab	Woods Hole	MA	02543	042104690	501 (c) 3	$6,394	$0	EXROP Program - Housing
UC- Los Angeles
UC- Los Angeles	Los Angeles	CA	90095	956006143	501 (c) 3	$16,172	$0	EXROP Program - Housing
Baylor Univ
Baylor Univ	Houston	TX	77030	741613878	501 (c) 3	$6,117	$0	EXROP Program - Housing
Univ of Texas
Univ of Texas	Austin	TX	78712	746000203	501 (c) 3	$5,550	$0	EXROP Program - Housing
Univ of Maryland
Univ of Maryland	Baltimore	MD	21201	526002033	501 (c) 3	$10,000	$0	Minority Serving Inst
Audubon Naturalist Soc
8940 Jones Mill Rd	Chevy Chase	MD	20815	530233715	501 (c) 3	$98,750	$0	Local Inititative
Chesapeake Bay Foundation
162 Prince George St	Annapolis	MD	21401	526065757	501 (c) 3	$300,000	$0	Local Inititative
PG County Public Schools
14201 School Lane	Upper Marlboro	MD	20772	526000992	501 (c) 3	$78,125	$0	Local Inititative
Montgomery Cty PS Educ Found
850 Hungerford Dr	Rockville	MD	20850	521804509	501 (c) 3	$1,090,000	$0	Local Inititative
Loudoun Cty Public Schools
21000 Education Court	Leesburg	VA	20176	546001395	501 (c) 3	$2,000,000	$0	PreCollege Science - Other
Yale Univ
Yale Univ	New Haven	CT	06520	060646973	501 (c) 3	$16,465	$0	Science Education Alliance
Gonzaga Univ
Gonzaga Univ	Spokane	WA	99258	910236600	501 (c) 3	$18,030	$0	Science Education Alliance
Univ of Pennsylvania
Univ of Pennsylvania	Philadelphia	PA	19104	231352685	501 (c) 3	$320,000	$0	Hanna Gray Scholars
Harvard Medical School
Harvard Medical School	Boston	MA	02115	042103580	501 (c) 3	$960,000	$0	Hanna Gray Scholars
UC - San Francisco
UC - San Francisco	San Francisco	CA	94143	946036493	501 (c) 3	$640,000	$0	Hanna Gray Scholars
Stanford Univ
Stanford Univ	Palo Alto	CA	94305	941156365	501 (c) 3	$320,000	$0	Hanna Gray Scholars
UC - Berkeley
UC - Berkeley	Berkeley	CA	94720	946002123	501 (c) 3	$320,000	$0	Hanna Gray Scholars
Memorial Sloan Kettering
Memorial Sloan Kettering	New York	NY	10021	131624182	501 (c) 3	$320,000	$0	Hanna Gray Scholars
Yale Univ
Yale Univ	New Haven	CT	06520	060646973	501 (c) 3	$320,000	$0	Hanna Gray Scholars
Univ of Texas-Southwestern
UT-Southwestern	Dallas	TX	75390	175600286	501 (c) 3	$320,000	$0	Hanna Gray Scholars
Brown Univ
Brown Univ	Providence	RI	02912	050258809	501 (c) 3	$320,000	$0	Hanna Gray Scholars
CA Inst of Technology
CA Inst of Technology	Pasadena	CA	91125	951643307	501 (c) 3	$640,000	$0	Hanna Gray Scholars
Salk Institute
Salk Institute	La Jolla	CA	92037	952160097	501 (c) 3	$320,000	$0	Hanna Gray Scholars
Brigham Young Univ
Brigham Young Univ	Provo	UT	84602	870217280	501 (c) 3	$28,993	$0	Science Education
Amer Soc - Cell Biology
8120 Woodmont Avenue	Bethesda	MD	20814	396054285	501 (c) 3	$450,000	$0	Science Education
National Academy of Sciences
2101 Constitution Avenue NW	Washington	DC	20001	530196932	501 (c) 3	$300,000	$0	Science Education
UC - San Diego
UC - San Diego	La Jolla	CA	92093	956006144	501 (c) 3	$3,068,831	$0	Medical Research
Fred Hutchinson Cancer Ctr
Fred Hutchinson Cancer Ctr	Seattle	WA	98109	237156071	501 (c) 3	$3,592,163	$0	Medical Research
Duke Univ
Duke Univ	Durham	NC	27706	560532129	501 (c) 3	$287,860	$0	Medical Research
Rutgers Univ
Rutgers Univ	Piscataway	NJ	08854	226001086	501 (c) 3	$1,328,545	$0	Medical Research
Texas A&M Univ
Texas AM Univ	College Station	TX	77843	746000531	501 (c) 3	$500,000	$0	Medical Research
National Jewish Center
National Jewish Center	Denver	CO	80206	742044647	501 (c) 3	$444,863	$0	Medical Research
UC- Los Angeles
UC- Los Angeles	Los Angeles	CA	90095	956006143	501 (c) 3	$500,000	$0	Medical Research
Columbia University
Columbia University	New York	NY	10027	135598093	501 (c) 3	$500,000	$0	Medical Research
Stanford Univ
Stanford Univ	Palo Alto	CA	94305	941156365	501 (c) 3	$500,000	$0	Medical Research
Univ of Washington
Univ of Washington	Seattle	WA	98195	916001537	501 (c) 3	$1,414,934	$0	Medical Research
Washington Univ
Washington Univ	St Louis	MO	63130	546001805	501 (c) 3	$279,685	$0	Medical Research
Univ of Colorado
Univ of Colorado	Boulder	CO	80309	846000555	501 (c) 3	$434,247	$0	Medical Research
CA Inst of Technology
CA Inst of Technology	Pasadena	CA	91125	951643307	501 (c) 3	$1,650,393	$0	Medical Research
Salk Institute
Salk Institute	La Jolla	CA	92037	952160097	501 (c) 3	$1,097,337	$0	Medical Research
Memorial Sloan Kettering
Memorial Sloan Kettering	New York	NY	10021	131624182	501 (c) 3	$500,000	$0	Medical Research
Tufts Univ
Tufts Univ	Boston	MA	02111	042103648	501 (c) 3	$340,892	$0	Medical Research
Yale Univ
Yale Univ	New Haven	CT	06520	060646973	501 (c) 3	$828,685	$0	Medical Research
Boston University
Boston University	Boston	MA	02215	042103547	501(c)3	$5,000	$0	Professors
Brandeis University
Brandeis University	Waltham	MA	02454	042103552	501(c)3	$74,500	$0	Professors

Field	Value	IRS element (for citing)
Total501c3 Org	83	Total501c3OrgCnt
Total Other Org	5	TotalOtherOrgCnt

Grants Other Asst To Indiv In US GrantsOtherAsstToIndivInUSGrp (3 entries)

Grant TypeGrantTypeTxt	RecipientRecipientCnt	Cash GrantCashGrantAmt
EXROP PROGRAM	85	$472,367
GILLIAM FELLOWSHIPS	96	$5,186,555
MEDICAL RESEARCH FELLOWSHIPS	79	$3,145,000

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	Schedule I, Part I, Line 2 Procedures for monitoring use of grant funds.	FormAndLineReferenceDesc
Explanation	HHMI awards institutional grants in support of precollege, undergraduate, and graduate education in the US through periodic national competitions for which select institutions are eligible to apply. Each program sets out specific criteria and objectives, proposals are evaluated by a panel of experts with the final selection made by HHMI leadership. The Institute also awards fellowships to international predoctoral students, to medical students seeking to conduct basic laboratory research, and to doctoral students (the Gilliam Fellows). These grants are also awarded on a competitive basis. A small number of grants are awarded based on direct application to HHMI for specific initiatives directly related to science education. The disbursement of funds occurs principally through biomedical research institutions, universities, and colleges. HHMI grantees are required to file annual progress reports that detail expenditures in accordance with the terms of the grant, as well as full description of program activities undertaken with the funds. These are subject to careful review and analysis by HHMI staff with more detailed review by the Institute auditors as warranted. The Institute continues to assess reporting requirements to ensure the quality and timeliness of both financial and programmatic reports. In addition to site visits made by HHMI staff, program directors meet on a regular basis to discuss their activities and share information about best educational practices.	ExplanationTxt

Schedule J IRS990ScheduleJ

Field	Value	IRS element (for citing)
First Class Or Charter Travel	Yes (X)	FirstClassOrCharterTravelInd
Travel For Companions	Yes (X)	TravelForCompanionsInd
Idemnification Gross Up Pmts	Yes (X)	IdemnificationGrossUpPmtsInd
Housing Allowance Or Residence	Yes (X)	HousingAllowanceOrResidenceInd
Written Policy Ref T And E Expnss	Yes (true)	WrittenPolicyRefTAndEExpnssInd
Substantiation Required	Yes (true)	SubstantiationRequiredInd
Compensation Committee	Yes (X)	CompensationCommitteeInd
Independent Consultant	Yes (X)	IndependentConsultantInd
Form990 Of Other Organizations	Yes (X)	Form990OfOtherOrganizationsInd
Written Employment Contract	Yes (X)	WrittenEmploymentContractInd
Compensation Survey	Yes (X)	CompensationSurveyInd
Board Or Committee Approval	Yes (X)	BoardOrCommitteeApprovalInd
Severance Payment	false	SeverancePaymentInd
Supplemental Nonqual Rtr Plan	false	SupplementalNonqualRtrPlanInd
Equity Based Comp Arrngm	false	EquityBasedCompArrngmInd
Comp Based On Revenue Of Flng Org	false	CompBasedOnRevenueOfFlngOrgInd
Comp Bsd On Rev Related Orgs	false	CompBsdOnRevRelatedOrgsInd
Comp Bsd Net Earns Flng Org	false	CompBsdNetEarnsFlngOrgInd
Comp Bsd Net Earns Rltd Orgs	false	CompBsdNetEarnsRltdOrgsInd
Any Non Fixed Payments	Yes (true)	AnyNonFixedPaymentsInd
Initial Contract Exception	Yes (true)	InitialContractExceptionInd
Rebuttable Presumption Proc	Yes (true)	RebuttablePresumptionProcInd

Rltd Org Officer Trst Key Empl RltdOrgOfficerTrstKeyEmplGrp (24 entries)

TitleTitleTxt	Base Compensation Filing OrgBaseCompensationFilingOrgAmt	Compensation Based On Rltd OrgsCompensationBasedOnRltdOrgsAmt	Bonus Filing OrganizationBonusFilingOrganizationAmount	Bonus Related OrganizationsBonusRelatedOrganizationsAmt	Other Compensation Filing OrgOtherCompensationFilingOrgAmt	Other Compensation Rltd OrgsOtherCompensationRltdOrgsAmt	Deferred Compensation Flng OrgDeferredCompensationFlngOrgAmt	Deferred Comp Rltd OrgsDeferredCompRltdOrgsAmt	Nontaxable Benefits Filing OrgNontaxableBenefitsFilingOrgAmt	Nontaxable Benefits Rltd OrgsNontaxableBenefitsRltdOrgsAmt	Total Compensation Filing OrgTotalCompensationFilingOrgAmt	Total Compensation Rltd OrgsTotalCompensationRltdOrgsAmt	Comp Report Prior990 Filing OrgCompReportPrior990FilingOrgAmt	Comp Report Prior990 Rltd OrgsCompReportPrior990RltdOrgsAmt
ERIN K O'SHEA PHD
PRESIDENT	$767,036	$0	$0	$0	$64,288	$0	$26,500	$0	$19,216	$0	$877,040	$0	$0	$0
DENNIS MCKEARIN PHD
VP OF OPERATIONS	$359,882	$0	$0	$0	$258,370	$0	$26,500	$0	$72,259	$0	$717,011	$0	$0	$0
SEAN B CARROLL PHD
VP FOR SCIENCE EDUCATION	$681,039	$0	$0	$0	$21,023	$0	$26,500	$0	$26,049	$0	$754,611	$0	$0	$0
HEIDI E HENNING ESQ
VP,GENERAL COUNSEL/SEC	$568,416	$0	$0	$0	$20,529	$0	$26,500	$0	$30,026	$0	$645,471	$0	$0	$0
DAVID CLAPHAM PHD
VP & CHIEF SCI OFF	$434,495	$0	$0	$0	$72,390	$0	$26,500	$0	$27,964	$0	$561,349	$0	$0	$0
GERALD M RUBIN PHD
VP&EXEC DIR,JANELIA RES CAMPUS	$744,547	$0	$0	$0	$28,558	$0	$26,500	$0	$88,126	$0	$887,731	$0	$0	$0
LANDIS ZIMMERMAN
VP & CHIEF INVESTMENT OFFICER	$951,269	$0	$1,969,944	$0	$22,221	$0	$26,500	$0	$29,807	$0	$2,999,741	$0	$0	$0
NITIN V KOTAK
CFO & TREASURER thru 6/17	$392,110	$0	$0	$0	$19,734	$0	$26,500	$0	$26,209	$0	$464,553	$0	$0	$0
LAUREN T SPILIOTES ESQ
DEP GENCOUNSEL/ASST SEC	$383,682	$0	$0	$0	$19,702	$0	$26,500	$0	$28,996	$0	$458,880	$0	$0	$0
SUSAN S PLOTNICK
ASSISTANT TREASURER & DIRECTOR-FINANCE	$239,602	$0	$2,000	$0	$942	$0	$23,036	$0	$33,175	$0	$298,755	$0	$0	$0
MONIQUE L MARCUS
CONTROLLER	$192,301	$0	$4,000	$0	$1,118	$0	$18,973	$0	$28,890	$0	$245,282	$0	$0	$0
RICHARD A PENDER
MAN DIR - US EQUITIES	$488,965	$0	$515,867	$0	$20,152	$0	$26,500	$0	$27,143	$0	$1,078,627	$0	$0	$0
GREGORY DENINNO
MAN DIR - PRIVATE EQUITIES	$285,204	$0	$163,622	$0	$3,020	$0	$26,500	$0	$33,443	$0	$511,789	$0	$0	$0
ROBERT J KOLYER JR
MAN DIR - DIVERSIFIED ASSETS	$482,645	$0	$875,903	$0	$21,217	$0	$26,500	$0	$26,881	$0	$1,433,146	$0	$0	$0
STEPHEN M KITSOULIS
MAN DIR - FIXED INCOME	$404,600	$0	$378,067	$0	$1,688	$0	$26,500	$0	$20,313	$0	$831,168	$0	$0	$0
MARK A BARNARD
MAN DIR - PRIVATE EQUITIES thru 6/16	$268,723	$0	$409,491	$0	$11,136	$0	$16,893	$0	$15,128	$0	$721,371	$0	$0	$0
DONALD KOCH
MAN DIR - PORTFOLIO STRATEGY	$357,254	$0	$676,456	$0	$18,334	$0	$26,500	$0	$27,865	$0	$1,106,409	$0	$0	$0
ANIL MADHOK
MAN DIR - INVESTMENTS & COO	$351,551	$0	$587,988	$0	$18,825	$0	$26,500	$0	$15,239	$0	$1,000,103	$0	$0	$0
THOMAS R CECH PHD
INVESTIGATOR	$623,602	$0	$0	$0	$31,531	$0	$26,500	$0	$21,433	$0	$703,066	$0	$0	$0
ERIC R KANDEL MD
SENIOR INVESTIGATOR	$586,736	$0	$0	$0	$28,832	$0	$26,500	$0	$33,465	$0	$675,533	$0	$0	$0
ROBERT TJIAN PHD
PRESIDENT thru 8/16	$1,079,206	$0	$0	$0	$215,642	$0	$26,500	$0	$35,063	$0	$1,356,411	$0	$0	$0
CHERYL A MOORE
EXECUTIVE VP & COO thru 1/16	$28,771	$0	$0	$0	$100,252	$0	$2,794	$0	$865	$0	$132,682	$0	$0	$0
JOHN PALMISANO
VP FOR INFORMATION TECHNOLOGY thru 8/16	$267,207	$0	$0	$0	$19,217	$0	$26,500	$0	$8,835	$0	$321,759	$0	$0	$0
KATHY WYSZYNSKI
VP, HUMAN RESOURCES thru 8/16	$263,028	$0	$0	$0	$19,147	$0	$26,500	$0	$14,423	$0	$323,098	$0	$0	$0

Supplemental Information Detail SupplementalInformationDetail (6 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
Schedule J, Part I, Line 1a First-class or charter travel	Under HHMI policies, HHMI reimburses its Trustees, President, Vice Presidents, and certain advisory group members for the reasonable cost of airfare at one class above coach for domestic or international flights of three hours or more. If a particular aircraft does not have a business class section, one class above coach may be first class. As an alternative, HHMI may reimburse for the cost of coach airfare plus the cost of an upgrade to travel at one level above coach for a flight of three hours or more. Such travel reimbursements are excluded from taxable compensation in accordance with HHMI's accountable plan. During fiscal year 2017, one key employee, two officers and four trustees flew first class.
Schedule J, Part I, Line 1a Travel for companions	Travel was provided for the former President's wife when he relocated to another HHMI site. This amount was included in the compensation of the former officer.
Schedule J, Part I, Line 1a Tax indemnification and gross-up payments	Under HHMI's moving expense reimbursement policy, if an employee is relocating at HHMI's request, HHMI will ordinarily provide a tax gross-up for the reimbursable moving expenses that must be treated as taxable to the employee. HHMI continued to follow this standard practice during the 2017 fiscal year. Internationally-assigned employees may receive tax gross-ups in respect of certain tax compliance and personal expenses incurred because of, and during, their overseas assignment. During fiscal year 2017, one of the officers received a tax gross-up.
Schedule J, Part I, Line 1a Housing allowance or residence for personal use	In fiscal year 2017, HHMI's President resided in an HHMI-owned house on the headquarters campus, for which she paid HHMI at a fair market rental rate. Because HHMI's President was also required to spend time at HHMI's Janelia campus, where she ran a research laboratory as well as attended meetings and participated in conferences, HHMI made an apartment available to her at that location. HHMI's Vice President and Executive Director, Janelia Research Campus, is required as a condition of employment to reside on the Janelia campus in housing built for that purpose. HHMI's Vice President and Chief Scientific Officer currently resides in an HHMI-owned apartment on the headquarters campus, for which he pays HHMI at a fair market rental rate. The Institute provides a housing assistance program for one individual who relocated to take a position with HHMI, which may be used to cover such individuals' mortgage or rent payments. In each case, the subsidy is treated as additional taxable compensation.
Schedule J, Part I, Line 7 Non-fixed payments	HHMI has an incentive compensation plan for its senior investment staff under which a portion of their compensation is determined based on performance of HHMI's portfolio against market benchmarks. HHMI also makes one-time payments to some of its other employees, including but not limited to officers, in recognition of exceptional performance.
Schedule J, Part I, Line 8 Payments on contract that is subject to the initial contract exception	When recruiting individuals for high-level positions, HHMI typically enters into initial contracts. HHMI has entered into initial contracts with a number of Vice Presidents. HHMI's standard practice is to have independent compensation consultants regularly review and confirm the reasonableness of compensation of HHMI's officers and key employees, regardless of whether the initial contract exception applies.

Schedule K IRS990ScheduleK

Tax Exempt Bonds Issues TaxExemptBondsIssuesGrp (4 entries)

Bond ReferenceBondReferenceCd	Bond Issuer EINBondIssuerEIN	CUSIPCUSIPNum	Bond IssuedBondIssuedDt	Issue PriceIssuePriceAmt	PurposePurposeDesc	DefeasedDefeasedInd	On Behalf Of IssuerOnBehalfOfIssuerInd	Pool FinancingPoolFinancingInd
LOUDOUN COUNTY IDA
A	521310230	545910AL5	2003-02-27	$500,000,000	FINANCE CONSTRUCTION OF JANELIA RESEARCH CAMPUS	false	false	false
LOUDOUN COUNTY IDA
B	521310230	545910AP6	2009-10-02	$23,000,000	FINANCE CONSTRUCTION OF JANELIA APT	false	false	false
LOUDOUN COUNTY IDA
C	521310230	545910AQ4	2013-05-15	$33,130,000	FINANCE CONSTRUCTION OF JANELIA APT B	false	false	false
MEDCO
D	521376562	574205FY1	2008-02-15	$83,500,000	FINANCE CONSTRUCTION OF HQ EXPANSION	false	false	false

Tax Exempt Bonds Proceeds TaxExemptBondsProceedsGrp (4 entries)

Bond ReferenceBondReferenceCd	RetiredRetiredAmt	Bond DefeasedBondDefeasedAmt	Total ProceedsTotalProceedsAmt	In Reserve FundInReserveFundAmt	Capitalized InterestCapitalizedInterestAmt	Refunding EscrowRefundingEscrowAmt	Issuance Costs From ProceedsIssuanceCostsFromProceedsAmt	Credit EnhancementCreditEnhancementAmt	Working Capital ExpendituresWorkingCapitalExpendituresAmt	Capital ExpendituresCapitalExpendituresAmt	Other Spent ProceedsOtherSpentProceedsAmt	UnspentUnspentAmt	Substantial CompletionSubstantialCompletionYr	Current RefundingCurrentRefundingInd	Advance RefundingAdvanceRefundingInd	Final Allocation MadeFinalAllocationMadeInd	Adequate Books And Rec MaintAdequateBooksAndRecMaintInd
A	$0	$0	$534,028,000	$0	$54,203,000	$0	$200,000	$0	$0	$479,625,000	$0	$0	2006	false	false	Yes (true)	Yes (true)
B	$0	$0	$23,022,042	$0	$904,914	$0	$0	$0	$43,305	$22,073,823	$0	$0	2011	false	false	Yes (true)	Yes (true)
C	$0	$0	$33,145,417	$0	$1,173,864	$0	$397,311	$0	$0	$31,574,242	$0	$0	2015	false	false	Yes (true)	Yes (true)
D	$0	$0	$84,953,297	$0	$5,954,687	$0	$631,673	$0	$0	$78,366,937	$0	$0	2010	false	false	Yes (true)	Yes (true)

Tax Exempt Bonds Private Bus Use TaxExemptBondsPrivateBusUseGrp (4 entries)

Bond ReferenceBondReferenceCd	Owning Bond Financed PropertyOwningBondFinancedPropertyInd	Any Lease ArrangementsAnyLeaseArrangementsInd	Mgmt Contract Bond Fincd PropMgmtContractBondFincdPropInd	Engage Bond Counsel ContractsEngageBondCounselContractsInd	Any Research AgreementsAnyResearchAgreementsInd	Engage Bond Counsel ResearchEngageBondCounselResearchInd	Bond Iss Meet Prvt Sec Pymt TestBondIssMeetPrvtSecPymtTestInd	Change In Use Bond Financed PropChangeInUseBondFinancedPropInd	Procs Nonqualified Bond RemdtdProcsNonqualifiedBondRemdtdInd
A	false	false	Yes (true)	Yes (true)	Yes (true)	Yes (true)	false	false	false
B	false	false	Yes (true)	Yes (true)	false		false	false	false
C	false	false	Yes (true)	Yes (true)	false		false	false	false
D	false	false	Yes (true)	Yes (true)	false		false	false	false

Tax Exempt Bonds Arbitrage TaxExemptBondsArbitrageGrp (4 entries)

Bond ReferenceBondReferenceCd	Form8038 T FiledForm8038TFiledInd	Variable Rate IssueVariableRateIssueInd	Hedge Identified In Bks And RecHedgeIdentifiedInBksAndRecInd	Term Of HedgeTermOfHedgePct	Superintegrated HedgeSuperintegratedHedgeInd	Hedge TerminatedHedgeTerminatedInd	Gross Proceeds Invested In GICGrossProceedsInvestedInGICInd	Gross Proceeds InvestedGrossProceedsInvestedInd	Written Proc To Monitor ReqsWrittenProcToMonitorReqsInd	Rebate Not Due YetRebateNotDueYetInd	Exception To RebateExceptionToRebateInd	No Rebate DueNoRebateDueInd
WELLS FARGO
A	Yes (true)	Yes (true)	Yes (true)	20.0	false	false	false	false	Yes (true)
JPMORGAN CHASE
B	false	Yes (true)	Yes (true)	30.0	false	false	false	false	Yes (true)	false	false	Yes (true)
WELLS FARGO BANK
C	false	Yes (true)	Yes (true)	30.0	false	false	false	false	Yes (true)	Yes (true)
JP MORGAN
D	false	Yes (true)	Yes (true)	30.0	false	false	false	false	Yes (true)	false	false	Yes (true)

Procedures Corrective Action ProceduresCorrectiveActionGrp (4 entries)

Bond ReferenceBondReferenceCd	Procedures Corrective ActionProceduresCorrectiveActionInd
A	false
B	false
C	false
D	false

Supplemental Information Detail SupplementalInformationDetail (6 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
Schedule K, Part I Part I	The bond issued February 27, 2003 also includes CUSIPS 545910AM3, 545910AG6, 545910AH4, 545910AJO, and 545910AK7.
Schedule K, Part II, Line 3 Part II, Line 3 - Total Proceeds	The bonds issued on 2/27/2003, 10/2/2009, 2/15/2008 and 5/15/2013 included interest income that made up the difference between the amount of the bond issue and the total proceeds.
Schedule K, Part IV Part IV - Name of Provider	For the bond issued on 2/27/2003 $375 million notional amount of the $500 million notional amount of swaps pertaining to this bond were integrated. The other counterparties pertaining to the bond issued on 2/27/2003 were Bank of America (30 years), Goldman Sachs (30 years) and JP Morgan (30 years.)
Schedule K, Part IV, Line 4a Part IV, Line 4a	Yes, In part for the bonds issued on 2/27/2003, 10/2/2009, 2/15/2008, 5/15/2008 and 5/15/2013.
Schedule K, Part IV, Line 2c COLUMN B	Issuer name: LOUDOUN COUNTY IDA The calculation for computing no rebate due was performed on 10/08/2014
Schedule K, Part IV, Line 2c COLUMN D	Issuer name: MEDCO The calculation for computing no rebate due was performed on 02/12/2013

Schedule K IRS990ScheduleK

Tax Exempt Bonds Issues TaxExemptBondsIssuesGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd

Issuer Name IssuerName

Field	Value	IRS element (for citing)
Business Name Line1	MEDCO	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Bond Issuer EIN	521376562	BondIssuerEIN
CUSIP	574205FZ8	CUSIPNum
Bond Issued	2008-05-15	BondIssuedDt
Issue Price	$76,500,000	IssuePriceAmt
Purpose	REFUNDING OF ISSUE TO FINANCE HQ CONSTRUCTION	PurposeDesc
Defeased	false	DefeasedInd
On Behalf Of Issuer	false	OnBehalfOfIssuerInd
Pool Financing	false	PoolFinancingInd

Tax Exempt Bonds Proceeds TaxExemptBondsProceedsGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Retired	$0	RetiredAmt
Bond Defeased	$0	BondDefeasedAmt
Total Proceeds	$76,500,000	TotalProceedsAmt
In Reserve Fund	$0	InReserveFundAmt
Capitalized Interest	$0	CapitalizedInterestAmt
Refunding Escrow	$0	RefundingEscrowAmt
Issuance Costs From Proceeds	$0	IssuanceCostsFromProceedsAmt
Credit Enhancement	$0	CreditEnhancementAmt
Working Capital Expenditures	$0	WorkingCapitalExpendituresAmt
Capital Expenditures	$0	CapitalExpendituresAmt
Other Spent Proceeds	$76,500,000	OtherSpentProceedsAmt
Unspent	$0	UnspentAmt
Substantial Completion	1993	SubstantialCompletionYr
Current Refunding	Yes (true)	CurrentRefundingInd
Advance Refunding	false	AdvanceRefundingInd
Final Allocation Made	Yes (true)	FinalAllocationMadeInd
Adequate Books And Rec Maint	Yes (true)	AdequateBooksAndRecMaintInd

Tax Exempt Bonds Private Bus Use TaxExemptBondsPrivateBusUseGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Private Bus Use By Others	0.0	PrivateBusUseByOthersPct
Private Bus Concerning UBI	0.0	PrivateBusConcerningUBIPct
Total Private Business Use	0.0	TotalPrivateBusinessUsePct

Tax Exempt Bonds Arbitrage TaxExemptBondsArbitrageGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Form8038 T Filed	Yes (true)	Form8038TFiledInd
Variable Rate Issue	Yes (true)	VariableRateIssueInd
Hedge Identified In Bks And Rec	Yes (true)	HedgeIdentifiedInBksAndRecInd

Hedge Provider Name HedgeProviderName

Field	Value	IRS element (for citing)
Business Name Line1	GOLDMAN SACHS	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Term Of Hedge	30.0	TermOfHedgePct
Superintegrated Hedge	false	SuperintegratedHedgeInd
Hedge Terminated	false	HedgeTerminatedInd
Gross Proceeds Invested In GIC	false	GrossProceedsInvestedInGICInd
Gross Proceeds Invested	false	GrossProceedsInvestedInd
Written Proc To Monitor Reqs	Yes (true)	WrittenProcToMonitorReqsInd

Procedures Corrective Action ProceduresCorrectiveActionGrp

Field	Value	IRS element (for citing)
Bond Reference	A	BondReferenceCd
Procedures Corrective Action	false	ProceduresCorrectiveActionInd

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (13 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
Form 990, Part III, Line 4a Program Service Description (continued)	(C) HIGHLIGHTS FROM HHMI RESEARCH LABORATORIES (FISCAL YEAR 2017) (1) Programming the Immune System to Attack Tumors Wendell Lim, University of California, San Francisco https://www.hhmi.org/news/programming-immune-system-attack-tumors HHMI scientists have developed a flexible method of programming cells to find and respond to molecular signals of disease. The highly customizable system, known as synNotch, can be used to deliver therapeutic molecules to a disease site or modulate local immune activity. Ultimately, its developers say, synNotch could enable a wide range of cellular therapies for cancer, autoimmune diseases, and other ailments. (2) New Tool Will Help Expand Scope of Neural Circuit Research Alla Karpova, Joshua Dudman, Adam Hantman, Loren Looger Janelia Research Campus https://www.hhmi.org/news/new-tool-will-help-expand-scope-neural-circuit-research Scientists at HHMI's Janelia Research Campus and the University of California, Berkeley have developed a powerful new tool for neuroscientists-a viral vector called rAAV2-retro, which efficiently enters and travels through the long neuronal projections that connect different regions of the brain. Genetically-encoded tools for labeling cells or monitoring or manipulating their activity can be packaged inside the virus and delivered to groups of neurons that signal to a specific part of the brain, creating new opportunities to study large-scale neural networks. (3) How the African Striped Mouse Got Its Stripes Hopi Hoekstra, Harvard University https://www.hhmi.org/news/how-african-striped-mouse-got-its-stripes A gene called Alx3 blocks the differentiation of pigment-producing cells in the skin of the African striped mouse, thus generating the mouse's characteristic light-colored stripes, new HHMI research shows. The same gene also determines the stripe pattern of North American chipmunks, and the similar stripe patterns evolved independently in these two groups of animals. How animal color patterns develop and evolve is a longstanding question in developmental biology. (4) Smart Microscope Adapts to Changes in Live Specimens Philipp Keller, Janelia Research Campus https://www.hhmi.org/news/smart-microscope-adapts-changes-live-specimens Janelia scientists have developed the first adaptive light-sheet microscope - an instrument that continuously analyzes and adapts to dynamic changes in a specimen and thereby improves spatial resolution. This "smart" light-sheet microscope analyzes a specimen continuously and adjusts its settings to optimize image quality. (5) Bacteria Spread Infection in Plants by Manipulating Water Level in Leaves Sheng Yang He, Michigan State University https://www.hhmi.org/news/bacteria-spread-infection-plants-manipulating-water-level-leaves HHMI researchers have identified the mechanisms that pathogenic bacteria use to waterlog the space between plant cells in the leaves, allowing the bacteria to reproduce and spread infection. About 30 percent of crop yields are lost to pathogens each year, but how plant diseases occur is still incompletely understood. (6) New Tools Will Drive Greater Understanding of Wheat Genes Jorge Dubcovsky, University of California, Davis https://www.hhmi.org/news/new-tools-will-drive-greater-understanding-wheat-genes HHMI scientists have developed a much-needed genetic resource that will greatly accelerate the study of gene functions in wheat. The resource, a collection of wheat seeds with more than 10 million sequenced and carefully catalogued genetic mutations, is freely available to wheat breeders and researchers, and is already aiding in the development of wheat plants with improved traits. (7) Abnormal Chromosome Number Sparks Large Variation in Yeast and Mice Angelika Amon, Massachusetts Institute of Technology https://www.hhmi.org/news/abnormal-chromosome-number-sparks-large-variation-yeast-and-mice New HHMI research reveals that adding or deleting chromosomes in cells and animals prompts a wide variety of outcomes. The work could help scientists better understand chromosomal abnormalities in humans. (8) Low Oxygen Reverses Mitochondrial Disease in Mice Vamsi Mootha, Massachusetts General Hospital https://www.hhmi.org/news/low-oxygen-reverses-mitochondrial-disease-mice HHMI researchers have demonstrated in mice that hypoxia (low oxygen) reverses brain damage caused by mitochondrial dysfunction. The approach might one day point to new therapies for people with Leigh syndrome and other mitochondrial disorders. (9) Artificial Intelligence Helps Build Brain Atlas of Fly Behavior Kristin Branson, Janelia Research Campus https://www.hhmi.org/news/artificial-intelligence-helps-build-brain-atlas-fly-behavior Scientists at HHMI's Janelia Research Campus created comprehensive brain maps linking different groups of neurons to specific behaviors, using a machine-learning program that annotated more than 225 days of videos of flies - a feat that would have taken humans some 3,800 years. (10) In-Depth Analysis of Metastatic Cancer Could Enable More Precise Treatments Arul Chinnaiyan, University of Michigan https://www.hhmi.org/news/depth-analysis-metastatic-cancer-could-enable-more-precise-treatments Five hundred cancer patients are getting an in-depth look at their genomes as part of a new clinical study that is revealing some of the key molecular drivers of metastatic cancers. Some of the patients, who were diagnosed with more than 20 different types of cancer among them, are now working with their physicians to use their genomic information to guide treatment options. The data are helping physicians match patients to clinical trials that address the precise DNA mutations that enable their cancers' growth. (11) Genetically Engineered Ants Showcase Smell's Role in Social Behavior Danny Reinberg, New York University https://www.hhmi.org/news/genetically-engineered-ants-showcase-smell-s-role-social-behavior After creating mutant Indian jumping ants with no sense of smell, HHMI researchers and their colleagues saw profound abnormalities in the ants' behavior and brains. The results show that the sense of smell is fundamental to maintaining harmony in ant colonies. (12) Origins of DNA Folding Suggested in Archaea Karolin Luger, University of Colorado, Boulder https://www.hhmi.org/news/origins-dna-folding-suggested-archaea By studying the 3-D structure of proteins bound to DNA in microbes called archaea, researchers have turned up surprising similarities to DNA packing in more complicated organisms. The archaeal DNA folding hints at the evolutionary origins of genome folding, a process that involves bending DNA and one that is remarkably conserved across all eukaryotes (organisms that have a defined nucleus surrounded by a membrane). (13) Expanding Access to New Tools to Study Childhood Cancers Michael Dyer, St. Jude Children's Research Hospital https://www.hhmi.org/news/expanding-access-new-tools-study-childhood-cancers HHMI scientists have created an extensive resource for studying pediatric cancers, which they are sharing widely to help accelerate research. The team grew cells from patient tumors in laboratory mice, and created nearly 100 models of 12 types of pediatric cancer. The researchers implanted the tumor cells into their organ of origin in the mice and carefully characterized them to ensure clinical relevance. Now, they are making samples freely available to the scientific community through the Childhood Solid Tumor Network. Researchers worldwide will also have access to data about the tumors' sensitivity to drugs, molecular profiles, and other features.
Form 990, Part III, Line 4b Program Service Description (continued)	(B) Graduate Science Education and Medical Research Training These programs focus on the development of innovative graduate education through grants to institutions and fellowships to students. HHMI's Gilliam Fellowships for Advanced Study Program supports PhD students who plan to pursue careers in academic science and who are committed to advancing diversity and inclusion in science. In FY17, HHMI awarded 39 fellowships. Each fellow will receive an annual award totaling $46,000, which includes a stipend, a training allowance, and an allowance for each fellow's institution, for up to three years. The applicant pool consists of alumni from HHMI's EXROP Program, and graduate students nominated by the program directors of non-MSTP T32 training grants and the INBRE grants awarded through the National Institute of General Medical Sciences (NIGMS). To be eligible, applicants must be enrolled in their second or third year of a PhD program in the life sciences, and not in an MD/PhD program. Applicants must be from racial, ethnic and other underrepresented groups in the sciences, including those from disadvantaged backgrounds, must aspire to careers in academic science, and must demonstrate a commitment to the advancement of diversity and inclusion in the sciences. A total of 135 students applied for the fellowships this year, including 26 EXROP alumni. This fiscal year, HHMI selected 79 medical and veterinary students to participate in the Medical Research Fellows Program. The fellowships enable students to take a year off from professional school to conduct laboratory research. The hope is that these students will one day choose to work at the crossroads of basic research and clinical medicine. Now, 28 years after the Medical Research Fellows Program was first launched, it has helped more than 1,700 medical, veterinary, and dental students establish a foothold in the research world. In this year's group, 18% of the fellows are from groups typically underrepresented in the biomedical sciences. In collaboration with HHMI, five partners - the American Society of Human Genetics (ASHG), Burroughs Wellcome Fund (BWF), Citizens United for Research in Epilepsy (CURE), Foundation Fighting Blindness (FFB), and Parkinson's Foundation (PF) - will fund eight of the 79 aspiring physician- and veterinarian- scientists, bringing the program's total investment to $3.4 million. This year, seven fellows from the 2016 class are supported by HHMI for an additional year. (C) Educational Media HHMI's Educational Media Group is comprised of BioInteractive and Tangled Bank Studios. BioInteractive, a resource for AP biology and college-level introductory biology teachers, has been in existence for more than 15 years and receives 2.5 million unique visitors per year through its website. The Educational Media Group produces science education resources including interactive multimedia materials, scientific animations, videos, in-class activities, educational lectures, as well as award-winning, broadcast-quality short films. The resources are then made available to educators online, through the BioInteractive.org website and YouTube channel, and at workshops and conventions. In February 2017, HHMI's Department of Science Education announced a yearlong collaboration with the Associated Press (AP) on two pilot projects designed to expand AP's science journalism. In the first project, AP will create and distribute a yearlong series of stories, profiles, videos and graphics dedicated to exploring new frontiers of genetic medicine. The content will focus on how new research and innovation in this rapidly evolving arena are increasing understanding of the causes of disease and leading to new kinds of treatments. The second project will examine a broad range of science topics in the news by presenting scientific evidence and putting it in context. The goal is to help readers stay up-to-date on the science community's latest research so they can make informed decisions on subjects ranging from the environment to public health. The multimedia series is set to include text, video, infographics and data visualizations. In October 2016, HHMI hosted a series of lectures exploring the topic "Ecology of Rivers and Coasts-Food Webs and Human Impacts." Two leading ecologists, Mary Power of the University of California, Berkeley, and Brian Silliman of Duke University, described the complex interactions between species and their environment in aquatic ecosystems to an audience of high school students from around the greater Washington, D.C., region. Using field experiments, the researchers illustrated how interactions among organisms such as fish, crab, insects, snails, and algae determine the vitality of rivers and coastal ecosystems and how these factors are affected by human activities. The se lectures, which are available on the BioInteractive website, bring current research into the science classroom, helping to bridge the gap between textbook curriculum and exciting new research developments. The Educational Media Group also developed and released its newest app, BiomeViewer. In the spirit of the very-popular EarthViewer app previously released by HHMI, BiomeViewer allows users to look at different biomes around the world, compare biomes, analyze temperature ranges, and study the fauna present there. (D) Tangled Bank Studios Tangled Bank Studios, LLC, HHMI's documentary film production unit, is dedicated to the creation of original science documentaries for broadcast, theatrical, and digital distribution. As an extension of HHMI's longstanding science education mission, the company aims to produce programs that capture compelling stories of discovery across all branches of scientific inquiry, with particular focus on the life sciences. New films released this year: The world premiere of The Lucky Specials took place in February 2017 in Johannesburg, South Africa. The film also aired on SABC1 in in South Africa. The feature-length film combines the best of fiction and non-fiction storytelling to demystify tuberculosis (TB), explaining how it spreads and how it can be treated. The film was produced by Discovery Learning Alliance and Quizzical Pictures in association with Tangled Bank Studios with additional support from the Wellcome Trust, USAID, and PEPFAR. In April 2017, Amazon Adventure, a giant screen film chronicling the adventures of Henry Walter Bates premiered at Smithsonian's National Museum of Natural History IMAX theatre. Bates, a contemporary of Charles Darwin, spent 11 years virtually alone in the Amazon collecting and documenting more than 14,000 species. He made the first scientific account of mimicry in animals and insects and provided an essential underpinning for the understanding of evolution and natural selection. As of December 2017, the film has engagements in 35 museums and science centers in the United States, China, Mexico Canada, Denmark, Australia and Hong Kong. The film was produced by SK Films in association with Tangled Bank Studios. It won five awards including Best Film and Best Film for Livelong Learning at the Giant Screen Cinema Association's 2017 conference; Tangled Bank's prior release - Spillover-Zika, Ebola & Beyond - was nominated for Outstanding Graphic Design and Art Direction. In August 2017, PBS premiered The Farthest - Voyager in Space, a two-hour special about NASA's historic Voyager mission to explore our solar system and beyond. The film debuted in conjunction with the 40th anniversary of the first Voyager launch. The documentary was an official selection in the 2017 Tribeca Film Festival as part of the festival's Viewpoints program.
Form 990, Part III, Line 4a Program Service Description (continued-1)	(D) Honors and Awards Received by HHMI Scientists (Fiscal Year 2017) Kaelin Receives Lasker Basic Medical Research Award The Albert and Mary Lasker Foundation selected HHMI investigator William G. Kaelin, Jr., of the Dana-Farber Cancer Institute, together with Peter J. Ratcliffe of the University of Oxford/Francis Crick Institute and Gregg L. Semenza of Johns Hopkins University School of Medicine, as recipients of the 2016 Albert Lasker Basic Medical Research Award. The Lasker Awards - considered among the most respected science prizes in the world - honor visionaries whose insight and perseverance have led to dramatic advances that will prevent disease and prolong life. The trio of scientists were honored for their discovery of the pathway by which cells from humans and most animals sense and adapt to changes in oxygen availability, a process that is essential for survival. Zoghbi Receives Canada Gairdner International Award for Research on Rett Syndrome The Gairdner Foundation selected HHMI Investigator Huda Zoghbi of Baylor College of Medicine as a recipient of the prestigious 2017 Canada Gairdner International Award in recognition of her contributions to medical science. The awards, which are presented annually, recognize scientists responsible for some of the world's most significant medical discoveries. Zoghbi, who became an HHMI investigator in 1996, was honored for the discovery of the genetic basis of Rett syndrome and its implications for autism spectrum disorders. HHMI Scientists Selected to Receive Breakthrough Prizes The Breakthrough Prize Foundation announced that HHMI investigators Stephen Elledge of Brigham and Women's Hospital, Roel Nusse of Stanford University, and Huda Zoghbi of Baylor College of Medicine are among scientists awarded the 2016 Breakthrough Prizes in Life Sciences. The prizes honor transformative advances toward understanding living systems and extending human life. The Breakthrough Prizes recognize pioneering work in physics and genetics, cosmology, and neurology and mathematics. Elledge was recognized for elucidating how eukaryotic cells sense and respond to damage in their DNA and for providing insights into the development and treatment of cancer. Nusse was selected for pioneering research on the Wnt pathway, one of the crucial intercellular signaling systems in development, cancer and stem cell biology. Zoghbi was honored for discoveries of the genetic causes and biochemical mechanisms of spinocerebellar ataxia and Rett syndrome, findings that have provided insight into the pathogenesis of neurodegenerative and neurological diseases. Each prize carries an award of $3 million. Vale Awarded Shaw Prize Ronald Vale, an HHMI investigator at the University of California, San Francisco, has won the Shaw Prize in Life Sciences and Medicine, which is awarded by the Shaw Prize Foundation in Hong Kong. Vale shared the $1.2 million award with molecular biologist Ian Gibbons, a visiting scholar at the University of California, Berkeley. The pair were honored for their discovery of microtubule-associated motor proteins, cellular engines that drive nerve cell growth and chromosome segregation. The Shaw Prize consists of three annual awards in astronomy, life science and medicine, and mathematical sciences. These international awards honor individuals who have achieved distinguished breakthroughs in academic and scientific research. The awards are dedicated to furthering societal progress, enhancing quality of life, and enriching humanity's spiritual civilization. Five HHMI Researchers Elected to National Academy of Medicine Five HHMI researchers have been elected to the National Academy of Medicine (NAM). The three HHMI investigators and two HHMI professors were among 70 new NAM members and nine international members elected. Established originally as the Institute of Medicine in 1970 by the National Academy of Sciences, the National Academy of Medicine addresses critical issues in health, science, medicine, and related policy and inspires positive actions across sectors. The new members are HHMI investigators, Bonnie Bassler, Princeton University; K. Christopher Garcia, Stanford University; Mark Krasnow, Stanford University; and HHMI professors, David Walt, Tufts University, and Huntington Willard, University of Chicago, President and Director, Marine Biological Laboratory. HHMI Scientists Elected to National Academy of Sciences Thirteen Howard Hughes Medical Institute scientists were elected to membership in the National Academy of Sciences. They are among 84 new members and 21 foreign associates from 15 countries elected in recognition of their distinguished and continuing achievements in original research. The National Academy of Sciences is a private organization of scientists and engineers dedicated to the furtherance of science and its use for the general welfare. The scientists are HHMI investigators, Stephen Bell, Massachusetts Institute of Technology; Dominique Bergmann, Stanford University; Sangeeta Bhatia, Massachusetts Institute of Technology; Chris Doe, University of Oregon; David Ginty, Harvard Medical School; Leemor Joshua-Tor, Cold Spring Harbor Laboratory; Richard Locksley, University of California, San Francisco; Scott Lowe, Memorial Sloan-Kettering Cancer Center; Ardem Patapoutian, The Scripps Research Institute; Craig Pikaard, Indiana University; Robert Siliciano, Johns Hopkins University; Rachel Wilson, Harvard Medical School; and HHMI professor, Jeffrey Moore, University of Illinois, Urbana Champaign. Deisseroth Awarded Else Krner Fresenius Prize for Medical Research Karl Deisseroth, an HHMI investigator at Stanford University was awarded the Else Krner Fresenius Prize, which was dedicated this year to research into the biological basis of psychiatric disorders. The international prize honors groundbreaking scientific contributions to the field and supports awardees' future work in medical research. Deisseroth was honored for his discoveries in optogenetics and hydrogel-tissue chemistry, as well as his research into the neural circuit basis of depression.
Form 990, Part III, Line 4b Program Service Description (Continued-1)	(E) Hanna Gray Fellows In June 2016, HHMI announced a new program to recruit and retain early-career scientists who are from gender, racial, ethnic, and other groups underrepresented in the life sciences, including those from disadvantaged backgrounds. Through an open competition, HHMI selects scientists early in their training to become Hanna H. Gray Fellows. Each fellow will receive funding for up to eight years, with mentoring and active involvement within the HHMI community. In this two-phase program, fellows will be supported from early postdoctoral training through several years of a tenure-track faculty position. In the first competition cycle, HHMI selected 15 fellows at the end of September 2017, and will invest a total of up to $25 million for their support over eight years. (F) Faculty Scholars HHMI, together with the Simons Foundation, and the Bill & Melinda Gates Foundation continued to provide grant support to 84 Faculty Scholars, early-career scientists who have great potential to make unique contributions to their field. The scientists represent 43 institutions across the United States. Through the Faculty Scholars Program, HHMI and its partner philanthropies will spend about $83 million over five years to support the first cohort of scientists selected to receive grants. The range of five-year grant award totals is $600,000-$1.8 million, including indirect costs. Faculty Scholars are required to devote at least 50 percent of their total effort to the direct conduct of research. (G) eLife - Open Access Journal HHMI, together with the Wellcome Trust and the Max Planck Society, continues to support a top tier scientific journal called eLife. The online journal follows an open access model and is directed by practicing scientists. eLife Sciences Publications, Ltd., is an independent non-profit entity governed by a separate board of directors. eLife began publishing research articles in late 2012 and is publishing articles online on a regular basis.
Form 990, Part VI, Line 11b Review of form 990 by governing body	The Howard Hughes Medical Institute's Form 990 is initially prepared by its Tax Compliance Department, in coordination with other HHMI departments as needed. The draft return is reviewed by senior management of HHMI and by attorneys in HHMI's Office of the General Counsel. Following these reviews and the resolution of any questions that have been raised, the draft return is reviewed by HHMI's outside tax preparer. Finally, a copy of the return is provided to the members of HHMI's Board of Trustees so that they have an opportunity to review and comment on the return before it is filed.
Form 990, Part VI, Line 12c Conflict of interest policy	In addition to HHMI's code of conduct, which addresses conflicts of interest and applies to all HHMI employees, officers, Trustees, and advisors, HHMI has specific conflict of interest policies for different categories of personnel. Under the HHMI policies that apply to Trustees, officers, and key employees, these individuals must disclose annually interests that could give rise to conflicts of interest, and must certify annually their compliance with the conflict of interest policy that applies to them. Annual disclosures and certifications are reviewed by HHMI's Office of the General Counsel, and by other HHMI managers as needed. The conflict of interest policy covering HHMI's Trustees also requires each Trustee to disclose to the other Trustees any actual or apparent conflict of interest with respect to a proposed HHMI transaction. If the other Trustees decide that there is only the appearance of a conflict of interest, and that it could not reasonably be considered to affect the independent, unbiased judgment of the disclosing Trustee with respect to the transaction at issue, no further action is required to address the apparent conflict. In all other cases, including all actual conflicts of interest, the disclosing Trustee is not permitted to participate in the deliberation or decision regarding the transaction under consideration, and must leave the room during the deliberation and vote. The conflict of interest policies covering HHMI's officers and key employees require each covered individual to obtain supervisory approval up to the level of HHMI's President before entering into an affiliation with or acquiring an interest of 1% or more in any entity that is or may become a recipient of HHMI funds. HHMI's President, in consultation with HHMI's General Counsel, may permit the affiliation or interest if it would not interfere with the covered individual's performance of his or her HHMI responsibilities, would not create the appearance of a conflict of interest, and would be consistent with sound business judgment. HHMI's President may set conditions on approval, for example that there be no remuneration to the covered individual. Proposed affiliations and interests of 1% or more of HHMI's President are subject to the approval of the Chairman of the Trustees.
Form 990, Part VI, Line 15a Process to establish compensation of top management official	The compensation for HHMI's President, other officers, and key employees is set using the following procedures: Every other year, the Audit and Compensation Committee of HHMI's Board of Trustees engages one or more independent compensation consultants to conduct a study of comparable market data. The study includes data for HHMI's President, other officers, and key employees. The independent compensation consultants also provide an opinion regarding the reasonableness of the compensation arrangements for the positions included in the study. The study includes comparable market data for all components of compensation for each person covered by the study, including base salary, incentive compensation (if any), and benefits. The Committee relies on the market data and opinion provided by the compensation consultant in making recommendations to the Board of Trustees regarding compensation for HHMI's President, other officers and key employees. The decision is made by independent Trustees. Any Trustee who has a conflict of interest with respect to a specific officer or key employee must recuse himself or herself from the decision on that person's compensation, and leave the meeting room during the debate and voting on it. In the alternate years when a study is not done, the Audit and Compensation Committee confirms with the independent compensation consultants that the range of any proposed merit increases for HHMI employees, including senior management, is reasonable compared with generally prevailing compensation increases in the market over the past year. The Committee relies on this advice in recommending compensation for HHMI's President, other officers and key employees, and the Board of Trustees relies on this advice in making compensation decisions. Recusal procedures are the same as in the years when a study is done. In each year, minutes of the discussions and decisions regarding compensation are prepared after each meeting and are submitted for approval at the next meeting. Approved minutes are kept in HHMI's records. All minutes include the date of the meeting, identify those Trustees who attended and voted on the compensation arrangements, and note any recusals of Trustees with a conflict of interest. The comparability studies and opinions relied on at the meeting are referenced in the minutes, and copies of these materials are also kept in HHMI's records. HHMI's Board of Trustees followed this process in August 2016 in determining compensation for the following positions for fiscal year 2017: President, Vice Presidents, and Managing Directors - Investments.
Form 990, Part VI, Line 15b Process to establish compensation of other employees	The compensation for HHMI's President, other officers, and key employees is set using the following procedures: Every other year, the Audit and Compensation Committee of HHMI's Board of Trustees engages one or more independent compensation consultants to conduct a study of comparable market data. The study includes data for HHMI's President, other officers, and key employees. The independent compensation consultants also provide an opinion regarding the reasonableness of the compensation arrangements for the positions included in the study. The study includes comparable market data for all components of compensation for each person covered by the study, including base salary, incentive compensation (if any), and benefits. The Committee relies on the market data and opinion provided by the compensation consultant in making recommendations to the Board of Trustees regarding compensation for HHMI's President, other officers and key employees. The decision is made by independent Trustees. Any Trustee who has a conflict of interest with respect to a specific officer or key employee must recuse himself or herself from the decision on that person's compensation, and leave the meeting room during the debate and voting on it. In the alternate years when a study is not done, the Audit and Compensation Committee confirms with the independent compensation consultants that the range of any proposed merit increases for HHMI employees, including senior management, is reasonable compared with generally prevailing compensation increases in the market over the past year. The Committee relies on this advice in recommending compensation for HHMI's President, other officers and key employees, and the Board of Trustees relies on this advice in making compensation decisions. Recusal procedures are the same as in the years when a study is done. In each year, minutes of the discussions and decisions regarding compensation are prepared after each meeting and are submitted for approval at the next meeting. Approved minutes are kept in HHMI's records. All minutes include the date of the meeting, identify those Trustees who attended and voted on the compensation arrangements, and note any recusals of Trustees with a conflict of interest. The comparability studies and opinions relied on at the meeting are referenced in the minutes, and copies of these materials are also kept in HHMI's records. HHMI's Board of Trustees followed this process in August 2016 in determining compensation for the following positions for fiscal year 2017: President, Vice Presidents, and Managing Directors - Investments.
Form 990, Part VI, Line 19 Required documents available to the public	HHMI's practice has been to make a copy of its charter and by-laws available on request. HHMI's code of conduct, which addresses conflicts of interest, is available to the public on the HHMI website. A downloadable copy of HHMI's most recent audited financial statements is also available to the public on the website. In addition, HHMI publishes "Year in Review" that provides a summary of each year's activity, expenditures, and financial performance.
Form 990, Part VIII, Line 11d Other Miscellaneous Revenue	Miscellaneous - Total Revenue: 129788, Related or Exempt Function Revenue: , Unrelated Business Revenue: , Revenue Excluded from Tax Under Sections 512, 513, or 514: 129788; Innovation Dissemination - Total Revenue: 58024, Related or Exempt Function Revenue: , Unrelated Business Revenue: , Revenue Excluded from Tax Under Sections 512, 513, or 514: 58024; External Shared Resources - Total Revenue: 5000, Related or Exempt Function Revenue: , Unrelated Business Revenue: , Revenue Excluded from Tax Under Sections 512, 513, or 514: 5000;
Form 990, Part XI, Line 9 Other changes in net assets or fund balances	Postretirement Changes Other Than Net Periodic Costs - 87375000; Grants refunds, write-offs etc. - 5153649;
Schedule A, Part I, Line 4 List of Hospital Affiliations	List of hospital affiliations for e-filing: Hospital, City, State, Zip Code- B&W Hospital, Boston, MA, 02115/ Children's Hosp, Boston, MA, 02115/ Children's Hosp, Cincinnati, OH, 45229/ Dana-Farber, Boston, MA, 02115/ Fred Hutch, Seattle, WA, 98109/ JHopkins Hosp, Baltimore, MD, 21205/ Mass Gen Hosp, Boston, MA, 02129/ MSKCC, New York, NY, 10021/ Nat'l Jewish, Denver, CO, 80206/ St Jude, Memphis, TN, 38105/ Duke-Duke Hosp, Durham, NC, 27706/ NYU-NYU Hosps, New York, NY, 10016/ OHSU-OHSU Hosp, Portland, OR, 97239/ Rockefeller-Hosp, New York, NY,10021/ Penn State Univ-Hosp, University Park, PA 16802/ Stanford-Hosp, Palo Alto, CA, 94305/ UCLA-Med Ctr, Los Angeles, CA, 90095/ UCSD-Med Ctr, San Diego, CA, 92093/ UCSF-UCSF Hosps, San Francisco, CA, 94143/ UIowa-UIowa Hosps, Iowa City, IA, 52242/ UMass-Med Ctr, Worcester, MA, 01605/ UMich-UMich Hosp, Ann Arbor, MI, 48109/ UPenn-UPenn Hosp, Philadelphia, PA, 19104/ UT-Austin-UT Hosp, Austin, TX, 78712/ UTSW-UTSW Hosps, Dallas, TX, 75390/ UUtah-UUtah Hosps, Salt Lake City, UT, 84112/ UWash-Med Ctr, Seattle, WA, 98195/ ADARC-aff hosp, New York, NY, 10016/ AECOM-affil hosps, New York, NY, 10461/ Baylor-aff hosps, Houston, TX, 77O3O/ Brandeis-aff hsps, Waltham, MA, 02254/ CalTech-aff hosps, Pasadena, CA, 91125/ CSHL-affil hosps, Cold Spring Harbor, NY, 11724/ Columbia-aff hsps, New York, NY, 10027/ Cornell-aff hosps, New York, NY, 14853/ Harvard-aff hosps, Cambridge, MA, 02138/ Indiana-affil hosp, Bloomington, IN, 47405/ JHU-affil hosps, Baltimore, MD, 21218/ MichSU-affil hosps, Lansing, MI, 48824/ MIT-affil hosps, Boston, MA, 02139/ NWU-affil hosps, Evanston, IL, 60208/ Princeton-aff hosps, Princeton, NJ, 08544/ Rutgers-affil hosp, Piscataway, NJ, 08854/ Salk-affil hosps ,La Jolla, CA, 92093/ Scripps-affil hosps, La Jolla, CA 92037/ Stowers-aff hosps, Kansas City, MO, 64110/ Tufts-aff hosps, Boston, MA, 02111/ UCB-affil hosps, Berkeley, CA, 94720/ UCDavis-affil hsps, Davis, CA, 95616/ UCR-affil hosps, Riversde, CA, 92521/ UCSC-aff hosps, Santa Cruz, CA, 95064/ UChi-affil hosp, Chicago, IL, 60637/ UColo-aff hosp, Boulder, CO, 80309/ Uillinois-aff hsp, Urbana, IL, 61801/ UMD-affil hosp, Baltimore, MD, 21201/ UMN-affil hosp, Minneapolis, MN 55414/ UNC-affil hosps, Chapel Hill, NC, 27599/ UOregon-aff hsp, Eugene, OR,97403/ UWisc-affil hosps, Madison, WI, 53706/ WashU-aff hosp, St Louis, MO, 63130/ YaleU-affil hosp, New Haven, CT, 06520/
Schedule A, Part I, Line 4 MRO Qualification	The Institute is a medical research organization for its taxable year ended August 31, 2017, as its expenditures of $ 782,251,870 on a cash basis for the year ended August 31 , 2016 exceeded the MRO requirement of $700,270,397 (3.5% of the HHMI endowment).

Schedule R IRS990ScheduleR

Id Disregarded Entities IdDisregardedEntitiesGrp (53 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	Primary ActivitiesPrimaryActivitiesTxt	Legal Domicile StateLegalDomicileStateCd	Total IncomeTotalIncomeAmt	End Of Year AssetsEndOfYearAssetsAmt	Business Name Line1DirectControllingEntityName/BusinessNameLine1Txt	EINEIN	Address Line1ForeignAddress/AddressLine1Txt	Province Or StateForeignAddress/ProvinceOrStateNm	CountryForeignAddress/CountryCd	Foreign PostalForeignAddress/ForeignPostalCd	Legal Domicile Foreign CountryLegalDomicileForeignCountryCd	Address Line2USAddress/AddressLine2Txt
HHMI II LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$38,953,403	$539,892,068	HHMI
HHMI IV LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI V LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI XII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$19,907,209	$93,410,990	HHMI
HHMI XVI LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$3,425	$0	HHMI
SPRUGOS INVESTMENTS II LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
SPRUGOS INVESTMENTS V LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$7,887,053	$0	HHMI
SPRUGOS INVESTMENTS VII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$59,660,624	$289,117,682	HHMI
SPRUGOS INVESTMENTS VIII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$50,126,781	$262,639,526	HHMI
SPRUGOS INVESTMENTS X LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
SPRUGOS INVESTMENTS XI LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$24,360,155	$94,502,975	HHMI
SPRUGOS INVESTMENTS XII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$26,071	$135,004	HHMI
SPRUGOS INVESTMENTS XIII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-AHEAD LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-ALEXA LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-CS CAPITAL LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-EUROCASTLE LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$1,928,694	$4,325,675	HHMI
PRIVATE EQUITY HOLDING-FAVRILLE LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-KAP LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-ROYCE LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-STORERETRO LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING-XENOPORT LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI FI I LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
JANELIA FARM HOLDING LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	VA	$0	$0	HHMI
SELDEN ISLAND HOLDING LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	VA	$0	$0	HHMI
HHMI I LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI III LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI VI LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI VII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI VIII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI IX LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI X LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI XI LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI XIII LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI XIV LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI XV LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
SPRUGOS INVESTMENTS LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
SPRUGOS INVESTMENTS III LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$66,889,007	$394,494,124	HHMI
SPRUGOS INVESTMENTS IV LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
SPRUGOS INVESTMENTS VI LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
SPRUGOS INVESTMENTS IX LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$29,479,552	$414,893,098	HHMI
SPRUGOS-FRENCH LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING II LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PRIVATE EQUITY HOLDING III LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
RELATIVE VALUE STRATEGIES LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
PSG LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	INVESTMENT	DE	$0	$0	HHMI
HHMI-SA LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	RESEARCH	DE	$0	$0	HHMI
TANGLED BANK STUDIOS LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	FILM PROD	DE	$0	$0	HHMI
MISSING LINK PRODUCTIONS LLC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	FILM PROD	DE	$0	$126	HHMI	471329820
LSV ADVANTAGE INTL III (CAYMAN) LTD
				INVESTMENT		$595,383	$19,488,965	HHMI	980689621	89 NEXUS WAY 2/F CANAMA BAY	GRAND CAYMAN	CJ	KY11205	CJ
LSV ADVANTAGE INTL III-B (CAYMAN) LTD
				INVESTMENT		$20,269,204	$96,323,748	HHMI	981087158	89 NEXUS WAY 2/F CAMANA BAY	GRAND CAYMAN	CJ	KY11205	CJ
Arosa Capital Management Midstream Fund LLC
c/o Arosa Capital Management LP	New York	NY	10036	Investment	DE	$31,196,866	$209,180,714	HHMI							120 West 45th St Ste 3700

Id Related Org Txbl Partnership IdRelatedOrgTxblPartnershipGrp (15 entries)

Address Line1ForeignAddress/AddressLine1Txt	CityForeignAddress/CityNm	CountryForeignAddress/CountryCd	Foreign PostalForeignAddress/ForeignPostalCd	EINEIN	Primary ActivitiesPrimaryActivitiesTxt	Legal Domicile Foreign CountryLegalDomicileForeignCountryCd	Business Name Line1DirectControllingEntityName/BusinessNameLine1Txt	Predominant Income TypePredominantIncomeTypeTxt	Share Of Total IncomeShareOfTotalIncomeAmt	Share Of EOY AssetsShareOfEOYAssetsAmt	Disproportionate AllocationsDisproportionateAllocationsInd	UBI Code VUBICodeVAmt	General Or Managing PartnerGeneralOrManagingPartnerInd	OwnershipOwnershipPct	Address Line1USAddress/AddressLine1Txt	Address Line2USAddress/AddressLine2Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	Legal Domicile StateLegalDomicileStateCd	Province Or StateForeignAddress/ProvinceOrStateNm
CERBERUS HH PARTNERS LP
190 ELGIN AVENUE	GEORGETOWN	CJ	KY19005	981102879	INVESTMENT	CJ	HHMI	Excluded	$12,838,539	$123,046,097	false	$0	false	0.94
GEM NPL CO-INV FUND LP
				464232021	INVESTMENT		HHMI	Excluded	$994,125	$2,263,375	Yes (true)	$446,435	false	0.67	900 NORTH MICHIGAN AVENUE SUITE 14	SUITE 1450	CHICAGO	IL	60611	IL
HHLF LP
				462823996	INVESTMENT		HHMI	Excluded	$4,755,424	$13,130,092	false	$0	false	0.84	555 5TH AVENUE FL18		NEW YORK	NY	10017	NY
LUMINUS CREDIT OPPORTUNITIES PIE I LP
				261963557	INVESTMENT		HHMI	Excluded	$737,722	$8,902,285	false	$0	false	0.99	1700 BROADWAY 38TH FLOOR		NEW YORK	NY	10019	NY
SOLUS OPPORTUNITIES FUND 2 LP
				463541945	INVESTMENT		HHMI	Excluded	-$1,123,881	$72,175,446	false	$0	false	0.95	410 PARK AVENUE 11TH FLOOR		NEW YORK	NY	10022	NY
CVI HH INVESTMENTS LP
				901010136	INVESTMENT		HHMI	Excluded	$11,904,786	$230,416,680	false	$0	false	1	9320 EXCELSIOR BLVD	MS144-7-2	HOPKINS	MN	55343	MN
ECHO STREET GOODCO SELECT II LP
				474827277	INVESTMENT		HHMI	Excluded	$11,946,949	$246,644,239	false	$0	false	0.99	10 EAST 53RD STREET	32ND FLOOR	NEW YORK	NY	10022	NY
GEM BVP CO-INV-A LP
				472251559	INVESTMENT		HHMI	Excluded	$0	$9,019,194	false	$0	false	1	900 NORTH MICHIGAN AVENUE	SUITE 1450	CHICAGO	IL	60611	IL
HH HOLDCO CO-INVESTMENT FUND LP
				300864915	INVESTMENT		HHMI	Excluded	$3,420,291	$80,904,923	false	$0	false	1	32 BROADWAY SUITE 1201		NEW YORK	NY	10004	NY
HH SG SECONDARY FUND LP
				473358493	INVESTMENT		HHMI	Excluded	-$1,870,626	$11,864,823	false	$51,960	false	0.93	825 THIRD AVENUE	10TH FLOOR	NEW YORK	NY	10022	NY
TOURMALET MATAWIN OFFSHORE FUND VI-A LP
89 NEXUS WAY CAMANA BAY		CJ	KY19007		INVESTMENT	CJ	HHMI	Excluded	$4,542,838	$67,643,062	false	$0	false	1							GRAND CAYMAN
HH ELLINGTON MASTER FUND LTD
				981020904	INVESTMENT		HHMI	Excluded	$2,696,817	$0	false	$1,005,760	false	0.82	53 FOREST AVENUE		OLD GREENWICH	CT	06870	CT
HH SG SECONDARY FUND II LP
				811581915	INVESTMENT		HHMI	Excluded	$406,009	$24,263,653	false	$0	false	0.96	825 THIRD AVENUE 10TH FLOOR		NEW YORK	NY	10022	NY
Arosa Midstream Fund LP
				811723636	Investment		Arosa Capital Management Midstream Fund LLC	Excluded	$31,196,866	$209,180,714	false	$0	false	0.9901	C/O Arosa Capital Management LP	120 West 45th St Ste 3700	New York	NY	10036	DE
ColHM Strategic Partners LP
				453436140	Investment		HHMI	Excluded	$5,562,880	$75,215,604	false	$0	false	0.9986	515 South Flower St 44th Fl		Los Angeles	CA	90071	CA

Id Related Org Txbl Corp Tr IdRelatedOrgTxblCorpTrGrp (14 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	EINEIN	Primary ActivitiesPrimaryActivitiesTxt	Legal Domicile StateLegalDomicileStateCd	Business Name Line1DirectControllingEntityName/BusinessNameLine1Txt	Entity TypeEntityTypeTxt	Share Of Total IncomeShareOfTotalIncomeAmt	Share Of EOY AssetsShareOfEOYAssetsAmt	OwnershipOwnershipPct	Controlled OrganizationControlledOrganizationInd	Address Line1ForeignAddress/AddressLine1Txt	Address Line2ForeignAddress/AddressLine2Txt	CityForeignAddress/CityNm	CountryForeignAddress/CountryCd	Legal Domicile Foreign CountryLegalDomicileForeignCountryCd	Province Or StateForeignAddress/ProvinceOrStateNm	Foreign PostalForeignAddress/ForeignPostalCd
HHMI REAL ESTATE INC
4000 JONES BRIDGE ROAD	CHEVY CHASE	MD	20815	203967202	INVESTMENT	DE	HHMI	C Corporation	$7,303	$950,676	1	Yes (true)
PLEASANT VALLEY INVESTMENTS LP
				980586696	INVESTMENT		HHMI	C Corporation	$20,269,190	$8,766,998	0.51	Yes (true)	99 QUEENS ROAD CENTRAL	UNIT 2112 21/F THE CENTER	HONG KONG	HK	CJ
HH ELLINGTON FUND LTD
					INVESTMENT		HHMI	C Corporation	$2,696,817	$0	1	Yes (true)	WALKER HOUSE 87 MARY STREET		GEORGETOWN	CJ	CJ	GR	KY19005
SPRUGOS MAURITIUS I LTD
					INVESTMENT		HHMI	C Corporation	-$2,873,897	$994,528	1	Yes (true)	33 EDITH CAVELL STREET		PORT LOUIS	MP	MP
HHMI CAYMAN I COMPANY
					INVESTMENT		HHMI	C Corporation	-$40,618	$218,554	1	Yes (true)	WALKER WALKER HOUSE MARY STREET	PO BOX 265GT	GEORGETOWN	CJ	CJ
CHALKSTREAM KOREA FUND INTERNATIONAL LP
				981248058	INVESTMENT		HHMI	C Corporation	$5,824,078	$50,448,527	1	Yes (true)	27 Hospital Road		George Town	CJ	CJ	Grand Cayman	KY19008
LSV ADVANTAGE INTERNATIONAL III LTD
				981300995	INVESTMENT		HHMI	C Corporation	-$251,148	$1,001,276	1	Yes (true)	89 NEXUS WAY 2/F CAMANA BAY			CJ	CJ	GRAND CAYMAN	KY11205
LSV ADVANTAGE INTERNATIONAL III-B LTD
				981315328	INVESTMENT		HHMI	C Corporation	$8,342,844	$27,224,468	1	Yes (true)	89 NEXUS WAY 2/F CAMANA BAY			CJ	CJ	GRAND CAYMAN	KY11205
COASTLAND RELATIVE VALUE FUND LTD
					INVESTMENT		HHMI	C Corporation	$22,131,938	$63,857,412	0.7	Yes (true)	WALKER HOUSE 87 MARY STREET		GEORGE TOWN	CJ	CJ	GRAND CAYMAN	KY19005
IRONSIDES PARTNERS SPECIAL SITUATIONS OFFSHORE FUND LTD
					INVESTMENT		HHMI	C Corporation	$893,539	$3,243,185	0.58	Yes (true)	PO BOX 309 UGLAND HOUSE			CJ	CJ	GRAND CAYMAN	11104
MARSHALL WACE MANAGED ACCOUNTS PLC-MW EUROPA FUND II
					INVESTMENT		HHMI	C Corporation	-$9,925,078	$157,078,640	1	Yes (true)	BEAUX LANE HOUSEMERCER ST LOWER		DUBLIN	EI	EI		2
NEWFOUNDLAND TERRANOVA OFFSHORE FUND
					INVESTMENT		HHMI	C Corporation	$17,132,548	$154,797,117	0.89	Yes (true)	89 NEXUS WAY CAMANA BAY			CJ	CJ	GRAND CAYMAN	KY19007
STEYN CAPITAL OFFSHORE HEDGE FUND
					INVESTMENT		HHMI	C Corporation	-$840,614	$117,249,960	1	Yes (true)	CASSIA COURT STE 716 10 MARKET ST		CAMANA BAY	CJ	CJ	GRAND CAYMAN	KY19006
LSV ADVANTAGE INTERNATIONAL III-C LTD
				981331158	INVESTMENT		HHMI	C Corporation	-$10,672	$10,672	1	Yes (true)	89 NEXUS WAY 2/F CAMANA BAY			CJ	CJ	GRAND CAYMAN	KY11205

Field	Value	IRS element (for citing)
Receipt Of Int Annts Rnts Rylts	false	ReceiptOfIntAnntsRntsRyltsInd
Gift Grnt Or Cap Contri To Oth Org	Yes (true)	GiftGrntOrCapContriToOthOrgInd
Gift Grnt Cap Contri From Oth Org	false	GiftGrntCapContriFromOthOrgInd
Loans Or Guarantees To Other Org	false	LoansOrGuaranteesToOtherOrgInd
Loans Or Guarantees From Oth Org	false	LoansOrGuaranteesFromOthOrgInd
Asset Sale To Other Org	false	AssetSaleToOtherOrgInd
Asset Purchase From Other Org	false	AssetPurchaseFromOtherOrgInd
Asset Exchange	false	AssetExchangeInd
Rental Of Facilities To Oth Org	false	RentalOfFacilitiesToOthOrgInd
Rental Of Fclts From Oth Org	false	RentalOfFcltsFromOthOrgInd
Perform Of Services For Oth Org	false	PerformOfServicesForOthOrgInd
Perform Of Services By Other Org	false	PerformOfServicesByOtherOrgInd
Sharing Of Facilities	false	SharingOfFacilitiesInd
Paid Employees Sharing	false	PaidEmployeesSharingInd
Reimbursement Paid To Other Org	false	ReimbursementPaidToOtherOrgInd
Reimbursement Paid By Other Org	false	ReimbursementPaidByOtherOrgInd
Transfer To Other Org	false	TransferToOtherOrgInd
Transfer From Other Org	Yes (true)	TransferFromOtherOrgInd

Transactions Related Org TransactionsRelatedOrgGrp (27 entries)

Transaction TypeTransactionTypeTxt	InvolvedInvolvedAmt	Method Of Amount DeterminationMethodOfAmountDeterminationTxt
CERBERUS HH PARTNERS LP
B	$10,305,040	FMV
ECHO STREET GOODCO SELECT II LP
B	$130,000,000	FMV
GEM BVP CO-INV-A LP
B	$2,000,000	FMV
HH HOLDCO CO-INVESTMENT FUND LP
B	$31,742,670	FMV
HH SG SECONDARY FUND II LP
B	$29,902,122	FMV
SOLUS OPPORTUNITIES FUND 2 LP
B	$20,046,436	FMV
TOURMALET MATAWIN OFFSHORE FUND VI-A LP
B	$46,000,000	FMV
SPRUGOS MAURITIUS I LTD
B	$26,146,856	FMV
LSV ADVANTAGE INTERNATIONAL III LTD
B	$622,067	FMV
LSV ADVANTAGE INTERNATIONAL III-B LTD
B	$3,538,063	FMV
NEWFOUNDLAND TERRANOVA OFFSHORE FUND
B	$100,450,049	FMV
STEYN CAPITAL OFFSHORE HEDGE FUND
B	$50,000,000	FMV
CERBERUS HH PARTNERS LP
S	$41,032,984	FMV
HH ELLINGTON FUND LTD
S	$32,772,287	FMV
HH HOLDCO CO-INVESTMENT FUND LP
S	$24,353,431	FMV
HH SG SECONDARY FUND LP
S	$3,851,789	FMV
HH SG SECONDARY FUND II LP
S	$12,737,363	FMV
HHLF LP
S	$26,739,354	FMV
LUMINUS CREDIT OPPORTUNITIES PIE I LP
S	$36,803,385	FMV
SOLUS OPPORTUNITIES FUND 2 LP
S	$48,488,708	FMV
TOURMALET MATAWIN OFFSHORE FUND VI-A LP
S	$16,385,433	FMV
SPRUGOS MAURITIUS I LTD
S	$25,139,919	FMV
NEWFOUNDLAND TERRANOVA OFFSHORE FUND
S	$75,450,048	FMV
CVI HH INVESTMENTS LP
S	$80,000,000	FMV
LSV ADVANTAGE INTERNATIONAL III-C LTD
B	$25,679,537	FMV
Arosa Midstream Fund LP
B	$29,180,714	FMV
ColHM Strategic Partners LP
S	$11,830,816	FMV