GRACE SCIENCE FOUNDATION: Form 990, tax year 2018

View the entire original 990 at ProPublica ↗

Organization
GRACE SCIENCE FOUNDATION (EIN 46-5727883)
Tax period
2018-01-01 to 2018-12-31
Filed
2019-05-15
IRS object ID
201931359349311978
Schema version
2018v3.1
Source
Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header ReturnHeader

FieldValueIRS element (for citing)
Return2019-05-15T16:33:00-05:00ReturnTs
Tax Period End2018-12-31TaxPeriodEndDt

Preparer Firm PreparerFirmGrp

FieldValueIRS element (for citing)
Preparer Firm EIN942682998PreparerFirmEIN

Preparer Firm Name PreparerFirmName

FieldValueIRS element (for citing)
Business Name Line1OUM & CO LLPBusinessNameLine1Txt

Preparer US Address PreparerUSAddress

FieldValueIRS element (for citing)
Address Line1601 CALIFORNIA STREET SUITE 1800AddressLine1Txt
CitySAN FRANCISCOCityNm
State AbbreviationCAStateAbbreviationCd
ZIP94108ZIPCd
FieldValueIRS element (for citing)
Return Type990ReturnTypeCd
Tax Period Begin2018-01-01TaxPeriodBeginDt

Filer Filer

FieldValueIRS element (for citing)
EIN465727883EIN

Business Name BusinessName

FieldValueIRS element (for citing)
Business Name Line1GRACE SCIENCE FOUNDATIONBusinessNameLine1Txt
FieldValueIRS element (for citing)
Business Name ControlGRACBusinessNameControlTxt
Phone4152557666PhoneNum

US Address USAddress

FieldValueIRS element (for citing)
Address Line1235 KANSAS STREET SUITE 200AddressLine1Txt
CitySAN FRANCISCOCityNm
State AbbreviationCAStateAbbreviationCd
ZIP94103ZIPCd

Business Officer BusinessOfficerGrp

FieldValueIRS element (for citing)
PersonMATTHEW R WILSEYPersonNm
Person TitlePRESIDENTPersonTitleTxt
Phone4152557666PhoneNum
Signature2019-05-15SignatureDt
Discuss With Paid PreparerYes (1)DiscussWithPaidPreparerInd

Preparer Person PreparerPersonGrp

FieldValueIRS element (for citing)
Preparer PersonBRADFORD WEISERTPreparerPersonNm
PTINP00044664PTIN
Phone4154343744PhoneNum

Filing Security Information FilingSecurityInformation

IP Address IPAddress

FieldValueIRS element (for citing)
I Pv4 Address38.122.223.90IPv4AddressTxt
FieldValueIRS element (for citing)
IP2019-05-15IPDt
IP Tm13:42:10IPTm
IP TimezonePDIPTimezoneCd
Filing License TypePFilingLicenseTypeCd
At Submission Creation Device IdDA39A3EE5E6B4B0D3255BFEF95601890AFD80709AtSubmissionCreationDeviceId
At Submission Filing Device IdB2956A4CF5B6977AD3DAA1C1E57949EE5A3782BFAtSubmissionFilingDeviceId
FieldValueIRS element (for citing)
Tax2018TaxYr
Build TS2019-02-21 02:37:17ZBuildTS

Form 990 IRS990

FieldValueIRS element (for citing)
Principal OfficerMATTHEW R WILSEYPrincipalOfficerNm

US Address USAddress

FieldValueIRS element (for citing)
Address Line1235 KANSAS STREET SUITE 200AddressLine1Txt
CitySAN FRANCISCOCityNm
State AbbreviationCAStateAbbreviationCd
ZIP94103ZIPCd
FieldValueIRS element (for citing)
Gross Receipts$1,204,078GrossReceiptsAmt
Group Return For Affiliates0GroupReturnForAffiliatesInd
Organization501c3Yes (X)Organization501c3Ind
Website AddressWWW.GRACESCIENCE.ORGWebsiteAddressTxt
Type Of Organization CorpYes (X)TypeOfOrganizationCorpInd
Formation2014FormationYr
Legal Domicile StateCALegalDomicileStateCd
Activity Or MissionTHE MISSION OF THE FOUNDATION IS TO SUPPORT AND FUND THE DEVELOPMENT OF LIFE-SAVING TREATMENT FOR PATIENTS THAT ARE DEFICIENT IN THE N-GLYCANESE ENZYME AND THOSE SUFFERING FROM RELATED GENETIC DISEASES.ActivityOrMissionDesc
Voting Members Governing Body7VotingMembersGoverningBodyCnt
Voting Members Independent7VotingMembersIndependentCnt
Total Employee0TotalEmployeeCnt
Total Volunteers10TotalVolunteersCnt
Total Gross UBI$0TotalGrossUBIAmt
Net Unrelated Bus Txbl Incm$0NetUnrelatedBusTxblIncmAmt
PY Contributions Grants$1,651,481PYContributionsGrantsAmt
CY Contributions Grants$1,187,802CYContributionsGrantsAmt
PY Program Service Revenue$0PYProgramServiceRevenueAmt
CY Program Service Revenue$0CYProgramServiceRevenueAmt
PY Investment Income$0PYInvestmentIncomeAmt
CY Investment Income$12,186CYInvestmentIncomeAmt
PY Other Revenue$25,626PYOtherRevenueAmt
CY Other Revenue$0CYOtherRevenueAmt
PY Total Revenue$1,677,107PYTotalRevenueAmt
CY Total Revenue$1,199,988CYTotalRevenueAmt
PY Grants And Similar Paid$696,567PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid$898,851CYGrantsAndSimilarPaidAmt
PY Benefits Paid To Members$0PYBenefitsPaidToMembersAmt
CY Benefits Paid To Members$0CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid$0PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid$0CYSalariesCompEmpBnftPaidAmt
PY Total Prof Fndrsng Expns$0PYTotalProfFndrsngExpnsAmt
CY Total Prof Fndrsng Expns$0CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense$0CYTotalFundraisingExpenseAmt
PY Other Expenses$223,947PYOtherExpensesAmt
CY Other Expenses$175,213CYOtherExpensesAmt
PY Total Expenses$920,514PYTotalExpensesAmt
CY Total Expenses$1,074,064CYTotalExpensesAmt
PY Revenues Less Expenses$756,593PYRevenuesLessExpensesAmt
CY Revenues Less Expenses$125,924CYRevenuesLessExpensesAmt
Total Assets BOY$2,109,224TotalAssetsBOYAmt
Total Assets EOY$2,196,374TotalAssetsEOYAmt
Total Liabilities BOY$16,500TotalLiabilitiesBOYAmt
Total Liabilities EOY$0TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY$2,092,724NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY$2,196,374NetAssetsOrFundBalancesEOYAmt
Info In Schedule O Part IIIYes (X)InfoInScheduleOPartIIIInd
MissionTHE MISSION OF THE FOUNDATION IS TO SUPPORT AND FUND THE DEVELOPMENT OF LIFE-SAVING TREATMENT FOR PATIENTS THAT ARE DEFICIENT IN THE N-GLYCANESE ENZYME AND THOSE SUFFERING FROM RELATED GENETIC DISEASES. THE ACTIVITIES OF THE FOUNDATION WILL INVOLVE PROVIDING GRANT FUNDING TO HOSPITALS AND MEDICAL RESEARCH FACILITIES WHICH ARE CONDUCTING MEDICAL RESEARCH IN VARIOUS FIELDS RELATING TO THE SEARCH FOR UNDERSTANDING AND TREATMENT OF THIS CONDITION, AND FOSTERING COLLABORATION BETWEEN ACADEMIA, RESEARCH INSTITUTIONS, HOSPITALS, PRIVATE COMPANIES, AND GOVERNMENTAL AGENCIES.MissionDesc
Significant New Program Srvc0SignificantNewProgramSrvcInd
Significant Change0SignificantChangeInd
Expense$255,345ExpenseAmt
Grant$250,000GrantAmt
DescSTANFORD UNIVERSITY (BERTOZZI LAB) - TEAM BEGAN INVESTIGATING A POSSIBLE ROLE FOR FERROPTOSIS AND OXIDATIVE STRESS IN THE PATHOLOGIES ASSOCIATED WITH NGLY1 DEFICIENCY. THESE FINDINGS TOUCH ON KNOWN PATHWAYS AND COULD THEREFORE INFORM POTENTIAL THERAPEUTIC STRATEGIES. ADDITIONALLY, THE TEAM MADE SIGNIFICANT PROGRESS ON A FLUOROGENIC PROBE TO DETECT NGLY1 ACTIVITY IN LIVE CELLS THAT DOES NOT REQUIRE THE CELLS TO BE GENETICALLY ENGINEERED. THE TEAM ALSO DEVELOPED A FIRST VERSION OF NGLY1-TURBOID, A SYSTEM DESIGNED TO IDENTIFY NGLY1 INTERACTORS AND POTENTIAL SUBSTRATES. THIS IS CRITICAL TO UNCOVERING PROTEINS INVOLVED IN NGLY1 FUNCTION AS WELL AS ADDITIONAL PROTEINS, LIKE NFE2L1, THAT NGLY1 MAY REGULATE THROUGH DEGLYCOSYLATION. SUCH PROTEINS COULD SERVE AS POTENTIAL TARGETS FOR A SMALL COMPOUND THERAPEUTIC AND COULD PROVIDE ESSENTIAL INSIGHT INTO NGLY1 BIOLOGY.Desc

Prog Srvc Accom Acty2 ProgSrvcAccomActy2Grp

FieldValueIRS element (for citing)
Expense$170,966ExpenseAmt
Grant$165,621GrantAmt
DescSALK INSTITUTE FOR BIOLOICAL SCIENCES (GAGE LAB) - TEAM GENERATED NEURONS FROM THE INDUCED PLURIPOTENT STEM CELLS (IPSCS) OF NGLY1 DEFICIENT PATIENTS TO CHARACTERIZE THEIR FUNCTIONAL CHANGES COMPARED WITH CONTROL SAMPLES. THEY DISCOVERED NEURITIC BEADING IN PATIENT NEURONS, A HALLMARK OF NEURONAL TOXICITY IN SEVERAL PATHOGENIC CONDITIONS. THEY ALSO OBSERVED THE PRESENCE OF PROTEIN AGGREGATES AND REDUCED SYNAPTIC ACTIVITY IN PATIENT CELLS COMPARED WITH CONTROLS. IN ADDITION TO NEURONS, THE TEAM ALSO DERIVED GLIAL PROGENITOR CELLS (GPCS) FROM IPSCS AND DID NOT OBSERVE THE FUNCTIONAL DEFECTS IN PRIMARY ASTROCYTES AS FOUND IN NEURONS. THESE DISCOVERIES IDENTIFIED PHENOTYPES THAT CAN BE LEVERAGED FOR HIGH-THROUGHPUT DRUG SCREENS AND PROVIDE INSIGHT AS TO THE CELL TYPES AFFECTED BY THE DISEASE IN PATIENTS.Desc

Prog Srvc Accom Acty3 ProgSrvcAccomActy3Grp

FieldValueIRS element (for citing)
Expense$128,395ExpenseAmt
Grant$123,050GrantAmt
DescMASSACHUSETTS GENERAL HOSPITAL (RUVKUN LAB) - TEAM CONTINUED THEIR ANALYSIS OF THE GENETIC MODIFIERS OF PROTEASOME DYSFUNCTION THEY PREVIOUSLY IDENTIFIED IN PNG-1 / NGLY1 DEFICIENT C. ELEGANS. THIS LED TO THE IDENTIFICATION OF A SPECIFIC PATHWAY WHOSE DISRUPTION APPEARS BENEFICIAL TO PROTEASOME DYSFUNCTION IN NGLY1 DEFICIENT ANIMALS, A FINDING THAT COULD TRANSLATE INTO A POTENTIAL THERAPY FOR THE DISEASE IN HUMANS. THEY ALSO DEMONSTRATED NGLY1 UNIQUELY ALLOWS EDITING OF THE UNDERLYING CODING SEQUENCE OF A GENE AT THE POST-TRANSLATIONAL LEVEL TO INFLUENCE THE ACTIVITY OF ONE OF ITS SUBSTRATES, THE KEY TRANSCRIPTIONAL REGULATOR SKN-1A / NFE2L1. ADDITIONALLY, THE TEAM DEMONSTRATED THAT SKN-1A/NFE2L1 IS ACTIVATED BY MISFOLDED PROTEINS, A FINDING WITH POTENTIAL RELEVANCE TO NEURODEGENERATIVE DISEASES. COLLECTIVELY, THESE RESULTS WERE SUBMITTED TO TWO SEPARATE, INFLUENTIAL JOURNALS.Desc

Prog Srvc Accom Acty Other ProgSrvcAccomActyOtherGrp (4 entries)

ExpenseExpenseAmtGrantGrantAmtDescDesc
$113,085$107,740UNIVERSITY OF TEXAS SOUTHWESTERN (YAN LAB) - TEAM TESTED SEVERAL COMPOUNDS THAT ARE KNOWN TO ACTIVATE A SPECIFIC PROTEIN INVOLVED IN THE RESPONSE TO OXIDATIVE STRESS FOR RESCUE OF DEFECTS IN NGLY1 DEFICIENT CELLS. THEY FOUND SULFORAPHANE (SFN) COULD SUBSTANTIALLY RESCUE INNATE IMMUNE SIGNALING AND MITOPHAGY DEFECTS AND IMPROVE MITOCHONDRIAL MORPHOLOGY AND HOMEOSTASIS. SFN TREATMENT OF PREGNANT NGLY1 -/- MICE ALSO SHOWED PARTIAL RESCUE OF EMBRYONIC LETHALITY, PROVIDING A PRECLINICAL STUDY OF THE DRUG IN MICE. THROUGH A GENETIC APPROACH, THE TEAM GENERATED EVIDENCE THAT NGLY1 DEFICIENCY TRIGGERS THE STING-DEPENDENT INNATE IMMUNE SENSING PATHWAY IN MOUSE EMBRYONIC STEM CELLS. THE TEAM ALSO GENERATED A TAMOXIFEN INDUCIBLE NGLY1 KO MOUSE MODEL THAT CAN BE USED FOR A VARIETY OF PURPOSE, FOR INSTANCE THE STUDY OF DISEASE PHENOTYPES, BIOMARKER EVALUATION, AND GENE THERAPY PROOF OF CONCEPT EXPERIMENTS.
$65,345$60,000UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (GAO LAB) - TEAM CONSTRUCTED THREE DIFFERENT RAAV VECTORS CONTAINING THE HUMAN NGLY1 (HNGLY1) TRANSGENE FOR CHARACTERIZATION OF THEIR DELIVERY AND EXPRESSION IN MICE TO UNDERSTAND THE EFFECTS OF OVEREXPRESSING HNGLY1 AND EVALUATE THE SAFETY OF DELIVERING HNGLY1 USING RAAV. THEY QUANTIFIED THE PRESENCE OF THE RAAV VECTOR GENOME AND HNGLY1 IN THE VARIOUS MOUSE TISSUES (INCLUDING LIVER, HIPPOCAMPUS, CORTEX, AND CEREBELLUM) AND DID NOT OBSERVE ANY DELETERIOUS EFFECTS ON THE MICE. THESE EXPERIMENTS ARE IMPORTANT PROOF OF CONCEPT EXPERIMENTS FOR AN NGLY1 GENE THERAPY APPROACH AS THEY DEMONSTRATED SUCCESSFULLY DELIVERY OF HNGLY1 USING DIFFERENT CONFIGURATIONS OF A RAAV VECTOR AND A LACK OF TOXICITY TO THE ANIMAL.
$55,345$50,000THE JACKSON LABORATORY (CAT LUTZ) - THE TEAM GENERATED A TRANSGENIC MOUSE EXPRESSING HUMAN NGLY1 IN A CONDITIONAL CRE-DEPENDENT MANNER, SHOWING IT COULD RESCUE THE MOUSE EMBRYONIC LETHALITY PHENOTYPE OF AN NGLY1 DEFICIENT MOUSE MODEL. THEY ALSO DEMONSTRATED A DOUBLE NGLY -/- / ENGASE -/- KNOCKOUT IS PARTIALLY VIABLE FOR A CERTAIN ALLELE OF NGLY1 AND BEGAN DEEP PHENOTYPIC ANALYSIS OF THESE MICE TO DETERMINE WHETHER THEY EXHIBIT ANY PATHOLOGIES. IF SO, THESE MICE COULD BE A USEFUL MODEL FOR TESTING POTENTIAL THERAPIES THAT COULD REVERSE PATHOLOGIES ASSOCIATED WITH NGLY1 DEFICIENCY (SINCE THE SINGLE KNOCKOUT MOUSE IS EMBRYONIC LETHAL). LASTLY, THE TEAM GENERATED SEVERAL TISSUE-SPECIFIC CONDITIONAL KNOCK-IN CLINICAL ALLELES OF NGLY1 TO HELP UNDERSTAND WHICH TISSUES ARE IMPORTANT IN THE DISEASE PATHOLOGY.
$147,783$142,440OTHER PROGRAM SERVICES ARE RELATED TO RESEARCH AND DEVELOPMENT TO UNDERSTAND AND CURE CARE DISEASES BEGINNING WITH NGLY1 DEFICIENCY.
FieldValueIRS element (for citing)
Total Other Prog Srvc Expense$381,558TotalOtherProgSrvcExpenseAmt
Total Other Prog Srvc Grant$360,180TotalOtherProgSrvcGrantAmt
Total Program Service Expenses$936,264TotalProgramServiceExpensesAmt
Described In Section501c3Yes (1)DescribedInSection501c3Ind
Schedule B RequiredYes (1)ScheduleBRequiredInd
Political Campaign Acty0PoliticalCampaignActyInd
Lobbying Activities0LobbyingActivitiesInd
Subject To Proxy Tax0SubjectToProxyTaxInd
Donor Advised Fund0DonorAdvisedFundInd
Conservation Easements0ConservationEasementsInd
Collections Of Art0CollectionsOfArtInd
Credit Counseling0CreditCounselingInd
Temp Or Permanent Endowments0TempOrPermanentEndowmentsInd
Report Land Building Equipment0ReportLandBuildingEquipmentInd
Report Investments Other Sec0ReportInvestmentsOtherSecInd
Report Program Related Invst0ReportProgramRelatedInvstInd
Report Other Assets0ReportOtherAssetsInd
Report Other Liabilities0ReportOtherLiabilitiesInd
Include FIN48 Footnote0IncludeFIN48FootnoteInd
Independent Audit Fincl Stmt0IndependentAuditFinclStmtInd
Consolidated Audit Fincl Stmt0ConsolidatedAuditFinclStmtInd
School Operating0SchoolOperatingInd
Foreign Office0ForeignOfficeInd
Foreign Activities0ForeignActivitiesInd
More Than5000 K To OrgYes (1)MoreThan5000KToOrgInd
More Than5000 K To Individuals0MoreThan5000KToIndividualsInd
Professional Fundraising0ProfessionalFundraisingInd
Fundraising Activities0FundraisingActivitiesInd
Gaming Activities0GamingActivitiesInd
Operate Hospital0OperateHospitalInd
Grants To OrganizationsYes (1)GrantsToOrganizationsInd
Grants To Individuals0GrantsToIndividualsInd
Schedule J Required0ScheduleJRequiredInd
Tax Exempt Bonds0TaxExemptBondsInd
Engaged In Excess Benefit Trans0EngagedInExcessBenefitTransInd
PY Excess Benefit Trans0PYExcessBenefitTransInd
Loan Outstanding0LoanOutstandingInd
Grant To Related Person0GrantToRelatedPersonInd
Business Rln With Org Mem0BusinessRlnWithOrgMemInd
Business Rln With Fam Mem0BusinessRlnWithFamMemInd
Business Rln With Officer Ent0BusinessRlnWithOfficerEntInd
Deductible Non Cash ContriYes (1)DeductibleNonCashContriInd
Deductible Art Contribution0DeductibleArtContributionInd
Terminate Operations0TerminateOperationsInd
Partial Liquidation0PartialLiquidationInd
Disregarded Entity0DisregardedEntityInd
Related Entity0RelatedEntityInd
Related Organization Ctrl Ent0RelatedOrganizationCtrlEntInd
Trnsfr Exmpt Non Chrtbl Rltd Org0TrnsfrExmptNonChrtblRltdOrgInd
Activities Conducted Prtshp0ActivitiesConductedPrtshpInd
Schedule O RequiredYes (1)ScheduleORequiredInd
IRP Document5IRPDocumentCnt
IRP Document W2 G0IRPDocumentW2GCnt
Employee0EmployeeCnt
Unrelated Bus Incm Over Limit0UnrelatedBusIncmOverLimitInd
Foreign Financial Account0ForeignFinancialAccountInd
Prohibited Tax Shelter Trans0ProhibitedTaxShelterTransInd
Taxable Party Notification0TaxablePartyNotificationInd
Nondeductible Contributions0NondeductibleContributionsInd
Quid Pro Quo Contributions0QuidProQuoContributionsInd
Form8282 Property Disposed Of0Form8282PropertyDisposedOfInd
Indoor Tanning Services0IndoorTanningServicesInd
Subj To Tax Rmnrtn Ex Prcht Pymt0SubjToTaxRmnrtnExPrchtPymtInd
Subject To Excs Tax Net Invst Inc0SubjectToExcsTaxNetInvstIncInd
Info In Schedule O Part VIYes (X)InfoInScheduleOPartVIInd
Governing Body Voting Members7GoverningBodyVotingMembersCnt
Independent Voting Member7IndependentVotingMemberCnt
Family Or Business RlnYes (1)FamilyOrBusinessRlnInd
Delegation Of Mgmt Duties0DelegationOfMgmtDutiesInd
Change To Org Documents0ChangeToOrgDocumentsInd
Material Diversion Or Misuse0MaterialDiversionOrMisuseInd
Members Or Stockholders0MembersOrStockholdersInd
Election Of Board MembersYes (1)ElectionOfBoardMembersInd
Decisions Subject To Approva0DecisionsSubjectToApprovaInd
Minutes Of Governing Body0MinutesOfGoverningBodyInd
Minutes Of Committees0MinutesOfCommitteesInd
Officer Mailing Address0OfficerMailingAddressInd
Local Chapters0LocalChaptersInd
Form990 Provided To Gvrn Body0Form990ProvidedToGvrnBodyInd
Conflict Of Interest PolicyYes (1)ConflictOfInterestPolicyInd
Annual Disclosure Covered Prsn0AnnualDisclosureCoveredPrsnInd
Regular Monitoring Enfrc0RegularMonitoringEnfrcInd
Whistleblower Policy0WhistleblowerPolicyInd
Document Retention Policy0DocumentRetentionPolicyInd
Compensation Process CEO0CompensationProcessCEOInd
Compensation Process Other0CompensationProcessOtherInd
Investment In Joint Venture0InvestmentInJointVentureInd
States Where Copy Of Return Is FldCAStatesWhereCopyOfReturnIsFldCd
Other WebsiteYes (X)OtherWebsiteInd
Upon RequestYes (X)UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

Business Name BusinessName

FieldValueIRS element (for citing)
Business Name Line1GRACE SCIENCE FOUNDATIONBusinessNameLine1Txt
FieldValueIRS element (for citing)
Phone4152557666PhoneNum

US Address USAddress

FieldValueIRS element (for citing)
Address Line1235 KANSAS STREET SUITE 200AddressLine1Txt
CitySAN FRANCISCOCityNm
State AbbreviationCAStateAbbreviationCd
ZIP94103ZIPCd
FieldValueIRS element (for citing)
No Listed Persons CompensatedYes (X)NoListedPersonsCompensatedInd

Form990 Part VII Section A Form990PartVIISectionAGrp (7 entries)

TitleTitleTxtAverage Hours Per WeekAverageHoursPerWeekRtIndividual Trustee Or DirectorIndividualTrusteeOrDirectorIndOfficerOfficerIndReportable Comp From OrgReportableCompFromOrgAmtReportable Comp From Rltd OrgReportableCompFromRltdOrgAmtOther CompensationOtherCompensationAmt
MATTHEW WILSEY
PRESIDENT20.00Yes (X)Yes (X)$0$0$0
EGON DURBAN
CHIEF FINANCIAL OFFICER1.00Yes (X)Yes (X)$0$0$0
KEN DRAZAN
SECRETARY1.00Yes (X)Yes (X)$0$0$0
PETE BRIGER
DIRECTOR1.00Yes (X)$0$0$0
CHELSEA CLINTON
DIRECTOR1.00Yes (X)$0$0$0
J TAYLOR CRANDALL
DIRECTOR1.00Yes (X)$0$0$0
ELLE STEPHENS
DIRECTOR1.00Yes (X)$0$0$0
FieldValueIRS element (for citing)
Total Reportable Comp From Org$0TotalReportableCompFromOrgAmt
Tot Reportable Comp Rltd Org$0TotReportableCompRltdOrgAmt
Total Other Compensation$0TotalOtherCompensationAmt
Indiv Rcvd Greater Than100 K0IndivRcvdGreaterThan100KCnt
Former Ofcr Employees Listed0FormerOfcrEmployeesListedInd
Total Comp Greater Than150 K0TotalCompGreaterThan150KInd
Compensation From Other Srcs0CompensationFromOtherSrcsInd
Cntrct Rcvd Greater Than100 K0CntrctRcvdGreaterThan100KCnt
All Other Contributions$1,187,802AllOtherContributionsAmt
Noncash Contributions$30,437NoncashContributionsAmt
Total Contributions$1,187,802TotalContributionsAmt

Investment Income InvestmentIncomeGrp

FieldValueIRS element (for citing)
Total Revenue Column$5,825TotalRevenueColumnAmt
Exclusion$5,825ExclusionAmt

Gross Amount Sales Assets GrossAmountSalesAssetsGrp

FieldValueIRS element (for citing)
Securities$10,451SecuritiesAmt

Less Cost Oth Basis Sales Expnss LessCostOthBasisSalesExpnssGrp

FieldValueIRS element (for citing)
Securities$4,090SecuritiesAmt

Gain Or Loss GainOrLossGrp

FieldValueIRS element (for citing)
Securities$6,361SecuritiesAmt

Net Gain Or Loss Investments NetGainOrLossInvestmentsGrp

FieldValueIRS element (for citing)
Total Revenue Column$6,361TotalRevenueColumnAmt
Exclusion$6,361ExclusionAmt

Total Revenue TotalRevenueGrp

FieldValueIRS element (for citing)
Total Revenue Column$1,199,988TotalRevenueColumnAmt
Related Or Exempt Func Income$0RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue$0UnrelatedBusinessRevenueAmt
Exclusion$12,186ExclusionAmt

Grants To Domestic Orgs GrantsToDomesticOrgsGrp

FieldValueIRS element (for citing)
Total$861,351TotalAmt
Program Services$861,351ProgramServicesAmt

Foreign Grants ForeignGrantsGrp

FieldValueIRS element (for citing)
Total$37,500TotalAmt
Program Services$37,500ProgramServicesAmt

Fees For Services Legal FeesForServicesLegalGrp

FieldValueIRS element (for citing)
Total$12,413TotalAmt
Management And General$12,413ManagementAndGeneralAmt

Fees For Services Accounting FeesForServicesAccountingGrp

FieldValueIRS element (for citing)
Total$4,275TotalAmt
Management And General$4,275ManagementAndGeneralAmt

Fees For Services Other FeesForServicesOtherGrp

FieldValueIRS element (for citing)
Total$81,250TotalAmt
Management And General$81,250ManagementAndGeneralAmt

Advertising AdvertisingGrp

FieldValueIRS element (for citing)
Total$8,760TotalAmt
Management And General$8,760ManagementAndGeneralAmt

Office Expenses OfficeExpensesGrp

FieldValueIRS element (for citing)
Total$12,086TotalAmt
Program Services$861ProgramServicesAmt
Management And General$11,225ManagementAndGeneralAmt

Travel TravelGrp

FieldValueIRS element (for citing)
Total$41,991TotalAmt
Program Services$36,552ProgramServicesAmt
Management And General$5,439ManagementAndGeneralAmt

Insurance InsuranceGrp

FieldValueIRS element (for citing)
Total$955TotalAmt
Management And General$955ManagementAndGeneralAmt

Other Expenses OtherExpensesGrp (3 entries)

DescDescTotalTotalAmtManagement And GeneralManagementAndGeneralAmt
BRANDING/LOGO/VIDEO/WEB$13,150$13,150
OTHER FEES (BANK, CREDI$173$173
FILING FEES$160$160

Total Functional Expenses TotalFunctionalExpensesGrp

FieldValueIRS element (for citing)
Total$1,074,064TotalAmt
Program Services$936,264ProgramServicesAmt
Management And General$137,800ManagementAndGeneralAmt
Fundraising$0FundraisingAmt

Cash Non Interest Bearing CashNonInterestBearingGrp

FieldValueIRS element (for citing)
BOY$2,109,224BOYAmt
EOY$2,192,300EOYAmt

Investments Pub Traded Sec InvestmentsPubTradedSecGrp

FieldValueIRS element (for citing)
EOY$4,074EOYAmt

Total Assets TotalAssetsGrp

FieldValueIRS element (for citing)
BOY$2,109,224BOYAmt
EOY$2,196,374EOYAmt

Grants Payable GrantsPayableGrp

FieldValueIRS element (for citing)
BOY$16,500BOYAmt
EOY$0EOYAmt

Total Liabilities TotalLiabilitiesGrp

FieldValueIRS element (for citing)
BOY$16,500BOYAmt
EOY$0EOYAmt
FieldValueIRS element (for citing)
Org Does Not Follow SFAS117Yes (X)OrgDoesNotFollowSFAS117Ind

Cap Stk Tr Prin Current Funds CapStkTrPrinCurrentFundsGrp

FieldValueIRS element (for citing)
BOY$0BOYAmt
EOY$0EOYAmt

Pd In Cap Srpls Land Bldg Eqp Fund PdInCapSrplsLandBldgEqpFundGrp

FieldValueIRS element (for citing)
BOY$0BOYAmt
EOY$0EOYAmt

Rtn Earn Endowment Incm Oth Fnds RtnEarnEndowmentIncmOthFndsGrp

FieldValueIRS element (for citing)
BOY$2,092,724BOYAmt
EOY$2,196,374EOYAmt

Total Net Assets Fund Balance TotalNetAssetsFundBalanceGrp

FieldValueIRS element (for citing)
BOY$2,092,724BOYAmt
EOY$2,196,374EOYAmt

Tot Liab Net Assets Fund Balance TotLiabNetAssetsFundBalanceGrp

FieldValueIRS element (for citing)
BOY$2,109,224BOYAmt
EOY$2,196,374EOYAmt
FieldValueIRS element (for citing)
Reconcilation Revenue Expnss$125,924ReconcilationRevenueExpnssAmt
Net Unrlzd Gains Losses Invst-$22,274NetUnrlzdGainsLossesInvstAmt
Other Changes In Net Assets$0OtherChangesInNetAssetsAmt
Method Of Accounting CashYes (X)MethodOfAccountingCashInd
Accountant Compile Or Review0AccountantCompileOrReviewInd
FS Audited0FSAuditedInd
Federal Grant Audit Required0FederalGrantAuditRequiredInd

Schedule A IRS990ScheduleA

FieldValueIRS element (for citing)
Public Organization170Yes (X)PublicOrganization170Ind

Gifts Grants Contri Rcvd170 GiftsGrantsContriRcvd170Grp

FieldValueIRS element (for citing)
Current Tax Year Minus4 Years$664,490CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years$1,560,381CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years$600,124CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year$1,677,107CurrentTaxYearMinus1YearAmt
Current Tax Year$1,157,365CurrentTaxYearAmt
Total$5,659,467TotalAmt

Total Calendar Year170 TotalCalendarYear170Grp

FieldValueIRS element (for citing)
Current Tax Year Minus4 Years$664,490CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years$1,560,381CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years$600,124CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year$1,677,107CurrentTaxYearMinus1YearAmt
Current Tax Year$1,157,365CurrentTaxYearAmt
Total$5,659,467TotalAmt
FieldValueIRS element (for citing)
Substantial Contributors Tot$1,760,433SubstantialContributorsTotAmt
Public Support Total170$3,899,034PublicSupportTotal170Amt
Total Support$5,659,467TotalSupportAmt
First5 Years170Yes (X)First5Years170Ind

Form990 Schedule A Part VI Form990ScheduleAPartVIGrp

FieldValueIRS element (for citing)
Form And Line ReferencePART II AND LINE 13FormAndLineReferenceDesc
ExplanationGRACE SCIENCE FOUNDATION WAS FORMED ON MAY 19, 2014. 2018 IS THE FOUNDATION'S FIFTH YEAR OF EXISTENCE.ExplanationTxt

Schedule B IRS990ScheduleB

Schedule F IRS990ScheduleF

FieldValueIRS element (for citing)
Subtotal Offices0SubtotalOfficesCnt
Subtotal Employees0SubtotalEmployeesCnt
Continuation Total Office0ContinuationTotalOfficeCnt
Continuation Total Employee0ContinuationTotalEmployeeCnt
Total Office0TotalOfficeCnt
Total Employee0TotalEmployeeCnt
Subtotal Spent$0SubtotalSpentAmt
Continuation Spent$0ContinuationSpentAmt
Total Spent$0TotalSpentAmt

Grants To Org Outside US GrantsToOrgOutsideUSGrp

FieldValueIRS element (for citing)
RegionCANADARegionTxt
Purpose Of GrantNGYL1 WORK IN MOFFAT'S LABS AT UNIVERSITY OF TORONTOPurposeOfGrantTxt
Cash Grant$37,500CashGrantAmt
Manner Of Cash DisbursementCHECKMannerOfCashDisbursementTxt
FieldValueIRS element (for citing)
Total501c3 Org1Total501c3OrgCnt
Transfer To Foreign Corp0TransferToForeignCorpInd
Interest In Foreign Trust0InterestInForeignTrustInd
Foreign Corp Ownership0ForeignCorpOwnershipInd
Passive Foreign Investmest Co0PassiveForeignInvestmestCoInd
Foreign Partnership0ForeignPartnershipInd
Boycott Countries0BoycottCountriesInd

Schedule I IRS990ScheduleI

FieldValueIRS element (for citing)
Grant Records MaintainedYes (1)GrantRecordsMaintainedInd

Recipient Table RecipientTable (8 entries)

Address Line1USAddress/AddressLine1TxtCityUSAddress/CityNmState AbbreviationUSAddress/StateAbbreviationCdZIPUSAddress/ZIPCdCash GrantCashGrantAmtPurpose Of GrantPurposeOfGrantTxtRecipient EINRecipientEINIRC SectionIRCSectionDesc
PERLARA PBC
6000 SHORELINE CT SUITE 204S SAN FRANCISCOCA94080$100,000ASSAY DEVELOPMENT & COMPOUND SCREENING
STANFORD UNIVERSITY
3145 PORTER DRIVEPALO ALTOCA94304$268,187NGLY1 WORK IN BERTOZZI/SNYDER/STEINMETZ LABS & NATURAL HISTORY PROTOCOL DEVELOPMENT941156365501(C)(3)
BROAD INSTITUTE
415 MAIN STREETCAMBRIDGEMA02142$39,050CMAP STUDY & GENETIC SEQUENCING263428781501(C)(3)
BAYLOR COLLEGE OF MEDICINE
1102 BATES AVENUE SUITE 48002HOUSTONTX77030$178,158NGLY1 WORK IN JAFAR-NEJAD LAB741613878501(C)(3)
SALK INSTITUTE FOR BIOLOGICAL STUDIES
10010 N TORREY PINES ROADLA JOLLACA92037$124,215NGLY1 WORK IN GAGE LAB952160097501(C)(3)
THE JACKSON LABORATORY
600 MAIN STREETBAR HARBORME04609$50,000NGLY1 WORK WITH CAT LUTZ010211513501(C)(3)
UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL
55 LAKE AVENUE NORTHWORCESTERMA01655$30,000NGLY1 WORK IN GAO LAB043167352501(C)(6)
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER
5323 HARRY HINES BLVDDALLASTX75390$71,741NGLY1 WORK IN YAN LAB756002868501(C)(6)
FieldValueIRS element (for citing)
Total501c3 Org7Total501c3OrgCnt
Total Other Org1TotalOtherOrgCnt

Supplemental Information Detail SupplementalInformationDetail

FieldValueIRS element (for citing)
Form And Line ReferencePART I, LINE 2:FormAndLineReferenceDesc
Explanation* BEFORE FUNDING A PRINCIPAL INVESTIGATOR, THE FOUNDATION REQUIRES A DETAILED PROPOSAL WITH OBJECTIVES AND MILESTONES * THE PROPOSALS ARE REVIEWED BY THE FOUNDATION AND SCIENTIFIC ADVISORY BOARD * THE PROPOSALS ARE OFTEN REVISED SEVERAL TIMES TO GET THE CORRECT FIT * ONCE FUNDED, EACH PRINCIPAL INVESTIGATOR SUBMITS A WRITTEN SUMMARY EVERY QUARTER * THIS UPDATE IS TWO TO THREE PAGES IN LENGTH * THE REPORTS DISCUSS PROGRESS, HIGHLIGHT ROADBLOCKS AND IDENTIFY WHERE THEY NEED HELP * THE FOUNDATION STEPS-IN WHERE APPROPRIATE TO MAKE SURE OBJECTIVES AND MILESTONES ARE MET * IN ADDITION TO QUARTERLY REPORTS, THE FOUNDATION HOLDS A MONTHLY CONFERENCE CALL WHERE TWO TO THREE PRINCIPAL INVESTIGATORS PRESENT THEIR LATEST WORK * BEYOND THE ABOVE TWO INITIATIVES, THE FOUNDATION HOLDS ONE TO TWO IN-PERSON MEETINGS PER YEAR * DR. KEVIN LEE (CHIEF SCIENTIFIC OFFICER), DR. SELINA DWIGHT (PROGRAM MANAGER), AND MATT WILSEY(PRESIDENT) CONTACT RESEARCHERS AND PRINCIPAL INVESTIGATORS ON A REGULAR BASIS VIA EMAIL, PHONE, OR ONE ON ONE MEETINGS THE PRESIDENT ENSURES THAT EVERY DOLLAR IS USED TO SUPPORT THE GRACE SCIENCE FOUNDATION'S MISSION.ExplanationTxt

Schedule M IRS990ScheduleM

Securities Publicly Traded SecuritiesPubliclyTradedGrp

FieldValueIRS element (for citing)
Non Cash CheckboxYes (X)NonCashCheckboxInd
Contribution3ContributionCnt
Noncash Contributions Rpt F990$30,437NoncashContributionsRptF990Amt
Method Of Determining RevenuesFAIR MARKET VALUEMethodOfDeterminingRevenuesTxt
FieldValueIRS element (for citing)
Any Property That Must Be Held0AnyPropertyThatMustBeHeldInd
Review Process Unusual NC Gifts0ReviewProcessUnusualNCGiftsInd
Third Parties Used0ThirdPartiesUsedInd

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (7 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
FORM 990, PART VI, SECTION A, LINE 2THE PRESIDENT OF THE FOUNDATION HAS IMMATERIAL OWNERSHIP INTEREST, IN THE INVESTMENTS OF FORTRESS AND SILVER LAKE, WHICH ARE MANAGED BY TWO OF THE DIRECTORS.
FORM 990, PART VI, SECTION A, LINE 7ATHE PRESIDENT OF THE FOUNDATION HAS AUTHORITY TO ELECT ONE OR MORE MEMBERS OF THE GOVERNING BODY.
FORM 990, PART VI, SECTION A, LINE 8ATHE GOVERNING BODY OF THE FOUNDATION DID NOT MEET DURING THE YEAR.
FORM 990, PART VI, SECTION A, LINE 8BTHE FOUNDATION DOES NOT HAVE ANY COMMITTEES.
FORM 990, PART VI, SECTION B, LINE 11BPRIOR TO FILING FROM 990, THE FOUNDATION'S PRESIDENT WILL REVIEW THE FORM.
FORM 990, PART VI, SECTION C, LINE 18AVAILABLE UPON REQUEST.
FORM 990, PART VI, SECTION C, LINE 19AVAILABLE UPON REQUEST.

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