LA JOLLA INSTITUTE FOR IMMUNOLOGY: Form 990, tax year 2019

View the entire original 990 at ProPublica ↗

Organization
LA JOLLA INSTITUTE FOR IMMUNOLOGY (EIN 33-0328688)
Tax period
2019-01-01 to 2019-12-31
Filed
2020-11-16
IRS object ID
202023219349307427
Schema version
2019v5.1
Source
Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header ReturnHeader

FieldValueIRS element (for citing)
Return2020-11-16T11:03:40-06:00ReturnTs
Tax Period End2019-12-31TaxPeriodEndDt

Preparer Firm PreparerFirmGrp

FieldValueIRS element (for citing)
Preparer Firm EIN861065772PreparerFirmEIN

Preparer Firm Name PreparerFirmName

FieldValueIRS element (for citing)
Business Name Line1Deloitte Tax LLPBusinessNameLine1Txt

Preparer US Address PreparerUSAddress

FieldValueIRS element (for citing)
Address Line1695 Town Center Drive Suite 1200AddressLine1Txt
CityCosta MesaCityNm
State AbbreviationCAStateAbbreviationCd
ZIP926261924ZIPCd
FieldValueIRS element (for citing)
Return Type990ReturnTypeCd
Tax Period Begin2019-01-01TaxPeriodBeginDt

Filer Filer

FieldValueIRS element (for citing)
EIN330328688EIN

Business Name BusinessName

FieldValueIRS element (for citing)
Business Name Line1La Jolla Institute for ImmunologyBusinessNameLine1Txt
FieldValueIRS element (for citing)
Business Name ControlLAJOBusinessNameControlTxt
Phone8587526500PhoneNum

US Address USAddress

FieldValueIRS element (for citing)
Address Line19420 Athena CircleAddressLine1Txt
CityLa JollaCityNm
State AbbreviationCAStateAbbreviationCd
ZIP920371387ZIPCd

Business Officer BusinessOfficerGrp

FieldValueIRS element (for citing)
PersonMichael DollarPersonNm
Person TitleCFOPersonTitleTxt
Phone8587526500PhoneNum
Signature2020-11-16SignatureDt
Discuss With Paid PreparerYes (1)DiscussWithPaidPreparerInd

Preparer Person PreparerPersonGrp

FieldValueIRS element (for citing)
Preparer PersonRebecca L LyonsPreparerPersonNm
PTINP01487105PTIN
Phone7144367100PhoneNum

Filing Security Information FilingSecurityInformation

IP Address IPAddress

FieldValueIRS element (for citing)
I Pv4 Address24.3.244.63IPv4AddressTxt
FieldValueIRS element (for citing)
IP2020-11-16IPDt
IP Tm10:49:16IPTm
IP TimezoneESIPTimezoneCd
Filing License TypePFilingLicenseTypeCd
At Submission Creation Device IdDA39A3EE5E6B4B0D3255BFEF95601890AFD80709AtSubmissionCreationDeviceId
At Submission Filing Device Id92426507D63AB8DCB9F8A2EED31D9394E8F3722BAtSubmissionFilingDeviceId
FieldValueIRS element (for citing)
Tax2019TaxYr
Build TS2021-01-29 14:40:06ZBuildTS

Form 990 IRS990

FieldValueIRS element (for citing)
Principal OfficerMichael DollarPrincipalOfficerNm

US Address USAddress

FieldValueIRS element (for citing)
Address Line19420 Athena CircleAddressLine1Txt
CityLa JollaCityNm
State AbbreviationCAStateAbbreviationCd
ZIP920371387ZIPCd
FieldValueIRS element (for citing)
Gross Receipts$68,642,455GrossReceiptsAmt
Group Return For Affiliates0GroupReturnForAffiliatesInd
Organization501c3Yes (X)Organization501c3Ind
Website Addresswww.lji.orgWebsiteAddressTxt
Type Of Organization CorpYes (X)TypeOfOrganizationCorpInd
Formation1988FormationYr
Legal Domicile StateCALegalDomicileStateCd
Activity Or MissionBiomedical research dedicated to improving human health through studies of the immune system.ActivityOrMissionDesc
Voting Members Governing Body26VotingMembersGoverningBodyCnt
Voting Members Independent25VotingMembersIndependentCnt
Total Employee479TotalEmployeeCnt
Total Volunteers65TotalVolunteersCnt
Total Gross UBI$710,139TotalGrossUBIAmt
Net Unrelated Bus Txbl Incm$112,962NetUnrelatedBusTxblIncmAmt
PY Contributions Grants$50,878,842PYContributionsGrantsAmt
CY Contributions Grants$58,096,830CYContributionsGrantsAmt
PY Program Service Revenue$5,548,673PYProgramServiceRevenueAmt
CY Program Service Revenue$7,349,335CYProgramServiceRevenueAmt
PY Investment Income-$249,669PYInvestmentIncomeAmt
CY Investment Income$1,740,790CYInvestmentIncomeAmt
PY Other Revenue$1,788,428PYOtherRevenueAmt
CY Other Revenue$1,455,500CYOtherRevenueAmt
PY Total Revenue$57,966,274PYTotalRevenueAmt
CY Total Revenue$68,642,455CYTotalRevenueAmt
PY Grants And Similar Paid$8,250PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid$769,190CYGrantsAndSimilarPaidAmt
PY Benefits Paid To Members$0PYBenefitsPaidToMembersAmt
CY Benefits Paid To Members$0CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid$32,116,302PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid$34,553,331CYSalariesCompEmpBnftPaidAmt
PY Total Prof Fndrsng Expns$0PYTotalProfFndrsngExpnsAmt
CY Total Prof Fndrsng Expns$0CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense$921,617CYTotalFundraisingExpenseAmt
PY Other Expenses$28,212,354PYOtherExpensesAmt
CY Other Expenses$34,836,716CYOtherExpensesAmt
PY Total Expenses$60,336,906PYTotalExpensesAmt
CY Total Expenses$70,159,237CYTotalExpensesAmt
PY Revenues Less Expenses-$2,370,632PYRevenuesLessExpensesAmt
CY Revenues Less Expenses-$1,516,782CYRevenuesLessExpensesAmt
Total Assets BOY$36,958,419TotalAssetsBOYAmt
Total Assets EOY$50,722,461TotalAssetsEOYAmt
Total Liabilities BOY$11,952,548TotalLiabilitiesBOYAmt
Total Liabilities EOY$27,233,372TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY$25,005,871NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY$23,489,089NetAssetsOrFundBalancesEOYAmt
MissionAt La Jolla Institute for Immunology, our scientists focus on understanding how the immune system works in order to promote human health and prevent disease. Our discoveries apply to many diseases, ranging from diabetes to heart disease, infectious diseases to cancer.MissionDesc
Significant New Program Srvc0SignificantNewProgramSrvcInd
Significant Change0SignificantChangeInd
Expense$60,998,379ExpenseAmt
Grant$769,190GrantAmt
Revenue$7,349,335RevenueAmt
DescLa Jolla Institute for Immunology ("LJI") is a private, nonprofit medical research organization that is recognized as a world leader in comprehensive research dedicated to understanding the intricacies and power of the immune system and applying that knowledge toward its goal of Life Without Disease. The Institute is home to 21 independent laboratories, each operated by a leading scientist handpicked for their creativity and pioneering spirit. Each of these labs is dedicated to understanding the far-reaching influence of the immune system and to training to the next generation of scientists, to promote human health and prevent a wide range of diseases.Desc
Total Program Service Expenses$60,998,379TotalProgramServiceExpensesAmt
Described In Section501c3Yes (1)DescribedInSection501c3Ind
Schedule B RequiredYes (1)ScheduleBRequiredInd
Political Campaign Acty0PoliticalCampaignActyInd
Lobbying Activities0LobbyingActivitiesInd
Subject To Proxy Tax0SubjectToProxyTaxInd
Donor Advised Fund0DonorAdvisedFundInd
Conservation Easements0ConservationEasementsInd
Collections Of Art0CollectionsOfArtInd
Credit Counseling0CreditCounselingInd
Donor Rstr Or Quasi Endowments0DonorRstrOrQuasiEndowmentsInd
Report Land Building EquipmentYes (1)ReportLandBuildingEquipmentInd
Report Investments Other Sec0ReportInvestmentsOtherSecInd
Report Program Related Invst0ReportProgramRelatedInvstInd
Report Other Assets0ReportOtherAssetsInd
Report Other Liabilities0ReportOtherLiabilitiesInd
Include FIN48 FootnoteYes (1)IncludeFIN48FootnoteInd
Independent Audit Fincl StmtYes (1)IndependentAuditFinclStmtInd
Consolidated Audit Fincl Stmt0ConsolidatedAuditFinclStmtInd
School Operating0SchoolOperatingInd
Foreign Office0ForeignOfficeInd
Foreign ActivitiesYes (1)ForeignActivitiesInd
More Than5000 K To OrgYes (1)MoreThan5000KToOrgInd
More Than5000 K To Individuals0MoreThan5000KToIndividualsInd
Professional Fundraising0ProfessionalFundraisingInd
Fundraising Activities0FundraisingActivitiesInd
Gaming Activities0GamingActivitiesInd
Operate Hospital0OperateHospitalInd
Grants To OrganizationsYes (1)GrantsToOrganizationsInd
Grants To Individuals0GrantsToIndividualsInd
Schedule J RequiredYes (1)ScheduleJRequiredInd
Tax Exempt Bonds0TaxExemptBondsInd
Engaged In Excess Benefit Trans0EngagedInExcessBenefitTransInd
PY Excess Benefit Trans0PYExcessBenefitTransInd
Loan OutstandingYes (1)LoanOutstandingInd
Grant To Related Person0GrantToRelatedPersonInd
Business Rln With Org Mem0BusinessRlnWithOrgMemInd
Business Rln With Fam MemYes (1)BusinessRlnWithFamMemInd
Business Rln With35 Ctrl EntYes (1)BusinessRlnWith35CtrlEntInd
Deductible Non Cash Contri0DeductibleNonCashContriInd
Deductible Art Contribution0DeductibleArtContributionInd
Terminate Operations0TerminateOperationsInd
Partial Liquidation0PartialLiquidationInd
Disregarded Entity0DisregardedEntityInd
Related Entity0RelatedEntityInd
Related Organization Ctrl Ent0RelatedOrganizationCtrlEntInd
Trnsfr Exmpt Non Chrtbl Rltd Org0TrnsfrExmptNonChrtblRltdOrgInd
Activities Conducted Prtshp0ActivitiesConductedPrtshpInd
Schedule O RequiredYes (1)ScheduleORequiredInd
IRP Document160IRPDocumentCnt
IRP Document W2 G0IRPDocumentW2GCnt
Backup Wthld ComplianceYes (1)BackupWthldComplianceInd
Employee479EmployeeCnt
Employment Tax Returns FiledYes (1)EmploymentTaxReturnsFiledInd
Unrelated Bus Incm Over LimitYes (1)UnrelatedBusIncmOverLimitInd
Form990 T FiledYes (1)Form990TFiledInd
Foreign Financial Account0ForeignFinancialAccountInd
Prohibited Tax Shelter Trans0ProhibitedTaxShelterTransInd
Taxable Party Notification0TaxablePartyNotificationInd
Nondeductible Contributions0NondeductibleContributionsInd
Quid Pro Quo Contributions0QuidProQuoContributionsInd
Form8282 Property Disposed Of0Form8282PropertyDisposedOfInd
Rcv Fnds To Pay Prsnl Bnft Cntrct0RcvFndsToPayPrsnlBnftCntrctInd
Pay Premiums Prsnl Bnft Cntrct0PayPremiumsPrsnlBnftCntrctInd
Indoor Tanning Services0IndoorTanningServicesInd
Subj To Tax Rmnrtn Ex Prcht Pymt0SubjToTaxRmnrtnExPrchtPymtInd
Subject To Excs Tax Net Invst Inc0SubjectToExcsTaxNetInvstIncInd
Info In Schedule O Part VIYes (X)InfoInScheduleOPartVIInd
Governing Body Voting Members26GoverningBodyVotingMembersCnt
Independent Voting Member25IndependentVotingMemberCnt
Family Or Business RlnYes (1)FamilyOrBusinessRlnInd
Delegation Of Mgmt Duties0DelegationOfMgmtDutiesInd
Change To Org Documents0ChangeToOrgDocumentsInd
Material Diversion Or Misuse0MaterialDiversionOrMisuseInd
Members Or Stockholders0MembersOrStockholdersInd
Election Of Board Members0ElectionOfBoardMembersInd
Decisions Subject To Approva0DecisionsSubjectToApprovaInd
Minutes Of Governing BodyYes (1)MinutesOfGoverningBodyInd
Minutes Of CommitteesYes (1)MinutesOfCommitteesInd
Officer Mailing Address0OfficerMailingAddressInd
Local Chapters0LocalChaptersInd
Form990 Provided To Gvrn BodyYes (1)Form990ProvidedToGvrnBodyInd
Conflict Of Interest PolicyYes (1)ConflictOfInterestPolicyInd
Annual Disclosure Covered PrsnYes (1)AnnualDisclosureCoveredPrsnInd
Regular Monitoring EnfrcYes (1)RegularMonitoringEnfrcInd
Whistleblower PolicyYes (1)WhistleblowerPolicyInd
Document Retention PolicyYes (1)DocumentRetentionPolicyInd
Compensation Process CEOYes (1)CompensationProcessCEOInd
Compensation Process OtherYes (1)CompensationProcessOtherInd
Investment In Joint Venture0InvestmentInJointVentureInd
States Where Copy Of Return Is FldAKStatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is FldALStatesWhereCopyOfReturnIsFldCd
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Upon RequestYes (X)UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

Business Name BusinessName

FieldValueIRS element (for citing)
Business Name Line1Michael DollarBusinessNameLine1Txt
FieldValueIRS element (for citing)
Phone8587526500PhoneNum

US Address USAddress

FieldValueIRS element (for citing)
Address Line19420 Athena CircleAddressLine1Txt
CityLa JollaCityNm
State AbbreviationCAStateAbbreviationCd
ZIP920371387ZIPCd

Form990 Part VII Section A Form990PartVIISectionAGrp (35 entries)

TitleTitleTxtAverage Hours Per WeekAverageHoursPerWeekRtAverage Hours Per Week Rltd OrgAverageHoursPerWeekRltdOrgRtIndividual Trustee Or DirectorIndividualTrusteeOrDirectorIndOfficerOfficerIndReportable Comp From OrgReportableCompFromOrgAmtReportable Comp From Rltd OrgReportableCompFromRltdOrgAmtOther CompensationOtherCompensationAmtKey EmployeeKeyEmployeeIndHighest Compensated EmployeeHighestCompensatedEmployeeIndFormer Ofcr Director TrusteeFormerOfcrDirectorTrusteeInd
Mitchell Kronenberg
President & CSO40.000.00Yes (X)Yes (X)$541,764$0$85,071
Richard S Bodman
Director2.000.00Yes (X)$0$0$0
Mark V Bowles
Director2.000.00Yes (X)$0$0$0
David A Brenner MD
Director2.000.00Yes (X)$0$0$0
Anthony Carr
Director2.000.00Yes (X)$0$0$0
Kristine Charton JD
Director2.000.00Yes (X)$0$0$0
Barton J Cohen
Director2.000.00Yes (X)$0$0$0
Michael D Coit
Director2.000.00Yes (X)$0$0$0
David Dominguez
Director2.000.00Yes (X)$0$0$0
Robert C Dynes PhD
Director2.000.00Yes (X)$0$0$0
Franois Ferre PhD
Director2.000.00Yes (X)$0$0$0
Genevive T Jacobs
Director2.000.00Yes (X)$0$0$0
Robert W Mahley MD PhD
Director2.000.00Yes (X)$0$0$0
John E Major Chair
Director2.000.00Yes (X)$0$0$0
Gail K Naughton PhD
Director2.000.00Yes (X)$0$0$0
Hunt Pettit
Director2.000.00Yes (X)$0$0$0
Mitsuo Satoh PhD
Director2.000.00Yes (X)$0$0$0
Sandor W Shapery JD
Director2.000.00Yes (X)$0$0$0
Larry S Spitcaufsky
Director2.000.00Yes (X)$0$0$0
Lynda Stuart MD PhD
Director2.000.00Yes (X)$0$0$0
Paul Thiel
Director (Start 08/2019)2.000.00Yes (X)$0$0$0
Thomas L Tullie
Director2.000.00Yes (X)$0$0$0
Pamela K Wasserman MPH
Director2.000.00Yes (X)$0$0$0
David R Webb PhD
Director2.000.00Yes (X)$0$0$0
Vanessa V Wertheim PhD MBA RN
Director2.000.00Yes (X)$0$0$0
Eric V Zwisler
Director2.000.00Yes (X)$0$0$0
Michael Dollar
CFO (Start 06/24/2019)40.000.00Yes (X)$146,986$0$13,682
Stephen Wilson
EVP, COO & CTO40.000.00$386,862$0$98,035Yes (X)
Michael Croft
Director Scientific Affairs40.000.00$323,176$0$71,232Yes (X)
Alessandro Sette
Division Head/Center Head/Prof40.000.00$425,416$0$96,752Yes (X)
Catherine Hedrick
Professor40.000.00$325,110$0$68,183Yes (X)
Klaus Ley
Division Head/Professor40.000.00$316,529$0$58,977Yes (X)
Stephen P Schoenberger
Professor40.000.00$288,333$0$82,469Yes (X)
Hilde Cheroutre
Division Head/Professor40.000.00$294,002$0$55,624Yes (X)
Jennifer K Keyes
CFO (End 06/18/2019)40.000.00$215,861$0$21,211Yes (X)
FieldValueIRS element (for citing)
Total Reportable Comp From Org$3,264,039TotalReportableCompFromOrgAmt
Tot Reportable Comp Rltd Org$0TotReportableCompRltdOrgAmt
Total Other Compensation$651,236TotalOtherCompensationAmt
Indiv Rcvd Greater Than100 K54IndivRcvdGreaterThan100KCnt
Former Ofcr Employees ListedYes (1)FormerOfcrEmployeesListedInd
Total Comp Greater Than150 KYes (1)TotalCompGreaterThan150KInd
Compensation From Other Srcs0CompensationFromOtherSrcsInd

Contractor Compensation ContractorCompensationGrp (5 entries)

Address Line1ContractorAddress/USAddress/AddressLine1TxtCityContractorAddress/USAddress/CityNmState AbbreviationContractorAddress/USAddress/StateAbbreviationCdZIPContractorAddress/USAddress/ZIPCdServicesServicesDescCompensationCompensationAmt
Finley & Cook
601 N Broadway PO Drawer 1447ShawneeOK748021447ERP software$303,686
A&A Labs LLC
9863 Pacific Heights Blvd Ste FSan DiegoCA92121Lab Supplies$273,099
Pestotnik LLP
501 West Broadway Ste 1025San DiegoCA92101Patient Related (Legal and Prof. Sv)$121,902
Moss-Adams LLP
PO Box 101822PasadenaCA911891822Auditor (Audit Organization Financial)$112,300
1903 Solutions LLC
2549 Eastbluff Dr Ste 378Newport BeachCA92660Computer Hardware/Fortigate and security$109,957
FieldValueIRS element (for citing)
Cntrct Rcvd Greater Than100 K5CntrctRcvdGreaterThan100KCnt
Government Grants$38,900,595GovernmentGrantsAmt
All Other Contributions$19,196,235AllOtherContributionsAmt
Total Contributions$58,096,830TotalContributionsAmt

Program Service Revenue ProgramServiceRevenueGrp

FieldValueIRS element (for citing)
DescConsortium RevenueDesc
Business900099BusinessCd
Total Revenue Column$7,349,335TotalRevenueColumnAmt
Related Or Exempt Func Income$7,349,335RelatedOrExemptFuncIncomeAmt
FieldValueIRS element (for citing)
Total Program Service Revenue$7,349,335TotalProgramServiceRevenueAmt

Investment Income InvestmentIncomeGrp

FieldValueIRS element (for citing)
Total Revenue Column$444,536TotalRevenueColumnAmt
Exclusion$444,536ExclusionAmt

Royalties Revenue RoyaltiesRevenueGrp

FieldValueIRS element (for citing)
Total Revenue Column$160,837TotalRevenueColumnAmt
Exclusion$160,837ExclusionAmt

Gross Amount Sales Assets GrossAmountSalesAssetsGrp

FieldValueIRS element (for citing)
Securities$1,296,254SecuritiesAmt

Less Cost Oth Basis Sales Expnss LessCostOthBasisSalesExpnssGrp

FieldValueIRS element (for citing)
Securities$0SecuritiesAmt

Gain Or Loss GainOrLossGrp

FieldValueIRS element (for citing)
Securities$1,296,254SecuritiesAmt

Net Gain Or Loss Investments NetGainOrLossInvestmentsGrp

FieldValueIRS element (for citing)
Total Revenue Column$1,296,254TotalRevenueColumnAmt
Exclusion$1,296,254ExclusionAmt

Other Revenue Misc OtherRevenueMiscGrp (3 entries)

DescDescBusinessBusinessCdTotal Revenue ColumnTotalRevenueColumnAmtUnrelated Business RevenueUnrelatedBusinessRevenueAmtExclusionExclusionAmt
Technical Services541900$441,832$441,832
Building Management541900$268,307$268,307
Contract Service900099$259,949$259,949

Miscellaneous Revenue MiscellaneousRevenueGrp

FieldValueIRS element (for citing)
Total Revenue Column$324,575TotalRevenueColumnAmt
Exclusion$324,575ExclusionAmt
FieldValueIRS element (for citing)
Other Revenue Total$1,294,663OtherRevenueTotalAmt

Total Revenue TotalRevenueGrp

FieldValueIRS element (for citing)
Total Revenue Column$68,642,455TotalRevenueColumnAmt
Related Or Exempt Func Income$7,349,335RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue$710,139UnrelatedBusinessRevenueAmt
Exclusion$2,486,151ExclusionAmt

Grants To Domestic Orgs GrantsToDomesticOrgsGrp

FieldValueIRS element (for citing)
Total$19,009TotalAmt
Program Services$19,009ProgramServicesAmt

Foreign Grants ForeignGrantsGrp

FieldValueIRS element (for citing)
Total$750,181TotalAmt
Program Services$750,181ProgramServicesAmt

Comp Current Ofcr Directors CompCurrentOfcrDirectorsGrp

FieldValueIRS element (for citing)
Total$1,666,808TotalAmt
Program Services$1,414,208ProgramServicesAmt
Management And General$216,919ManagementAndGeneralAmt
Fundraising$35,681FundraisingAmt

Comp Disqual Persons CompDisqualPersonsGrp

FieldValueIRS element (for citing)
Total$237,072TotalAmt
Program Services$201,156ProgramServicesAmt
Management And General$35,916ManagementAndGeneralAmt

Other Salaries And Wages OtherSalariesAndWagesGrp

FieldValueIRS element (for citing)
Total$24,931,232TotalAmt
Program Services$21,075,216ProgramServicesAmt
Management And General$3,394,139ManagementAndGeneralAmt
Fundraising$461,877FundraisingAmt

Pension Plan Contributions PensionPlanContributionsGrp

FieldValueIRS element (for citing)
Total$2,572,417TotalAmt
Program Services$2,155,532ProgramServicesAmt
Management And General$358,357ManagementAndGeneralAmt
Fundraising$58,528FundraisingAmt

Other Employee Benefits OtherEmployeeBenefitsGrp

FieldValueIRS element (for citing)
Total$3,322,820TotalAmt
Program Services$2,861,979ProgramServicesAmt
Management And General$379,780ManagementAndGeneralAmt
Fundraising$81,061FundraisingAmt

Payroll Taxes PayrollTaxesGrp

FieldValueIRS element (for citing)
Total$1,822,982TotalAmt
Program Services$1,527,551ProgramServicesAmt
Management And General$253,955ManagementAndGeneralAmt
Fundraising$41,476FundraisingAmt

Fees For Services Legal FeesForServicesLegalGrp

FieldValueIRS element (for citing)
Total$837,238TotalAmt
Program Services$572,941ProgramServicesAmt
Management And General$264,297ManagementAndGeneralAmt

Fees For Services Accounting FeesForServicesAccountingGrp

FieldValueIRS element (for citing)
Total$312,402TotalAmt
Management And General$312,402ManagementAndGeneralAmt

Fees For Services Other FeesForServicesOtherGrp

FieldValueIRS element (for citing)
Total$327,513TotalAmt
Program Services$67,222ProgramServicesAmt
Management And General$181,085ManagementAndGeneralAmt
Fundraising$79,206FundraisingAmt

Advertising AdvertisingGrp

FieldValueIRS element (for citing)
Total$246,802TotalAmt
Program Services$6,361ProgramServicesAmt
Management And General$238,855ManagementAndGeneralAmt
Fundraising$1,586FundraisingAmt

Office Expenses OfficeExpensesGrp

FieldValueIRS element (for citing)
Total$155,030TotalAmt
Program Services$107,069ProgramServicesAmt
Management And General$29,477ManagementAndGeneralAmt
Fundraising$18,484FundraisingAmt

Information Technology InformationTechnologyGrp

FieldValueIRS element (for citing)
Total$1,682,425TotalAmt
Program Services$565,763ProgramServicesAmt
Management And General$1,107,760ManagementAndGeneralAmt
Fundraising$8,902FundraisingAmt

Occupancy OccupancyGrp

FieldValueIRS element (for citing)
Total$7,137,151TotalAmt
Program Services$6,479,208ProgramServicesAmt
Management And General$623,523ManagementAndGeneralAmt
Fundraising$34,420FundraisingAmt

Travel TravelGrp

FieldValueIRS element (for citing)
Total$728,607TotalAmt
Program Services$570,409ProgramServicesAmt
Management And General$126,833ManagementAndGeneralAmt
Fundraising$31,365FundraisingAmt

Conferences Meetings ConferencesMeetingsGrp

FieldValueIRS element (for citing)
Total$211,092TotalAmt
Program Services$176,687ProgramServicesAmt
Management And General$25,546ManagementAndGeneralAmt
Fundraising$8,859FundraisingAmt

Depreciation Depletion DepreciationDepletionGrp

FieldValueIRS element (for citing)
Total$1,886,851TotalAmt
Program Services$1,758,919ProgramServicesAmt
Management And General$127,932ManagementAndGeneralAmt

Insurance InsuranceGrp

FieldValueIRS element (for citing)
Total$219,493TotalAmt
Program Services$202,123ProgramServicesAmt
Management And General$16,275ManagementAndGeneralAmt
Fundraising$1,095FundraisingAmt

Other Expenses OtherExpensesGrp (4 entries)

DescDescTotalTotalAmtProgram ServicesProgramServicesAmtManagement And GeneralManagementAndGeneralAmtFundraisingFundraisingAmt
Lab Supplies Service$10,015,899$10,015,899
Consortium$6,021,321$6,021,321
Other Expenses$2,170,425$2,170,425
Manuscripts Costs$1,693,741$1,200,978$433,686$59,077

All Other Expenses AllOtherExpensesGrp

FieldValueIRS element (for citing)
Total$1,190,726TotalAmt
Program Services$1,078,222ProgramServicesAmt
Management And General$112,504ManagementAndGeneralAmt

Total Functional Expenses TotalFunctionalExpensesGrp

FieldValueIRS element (for citing)
Total$70,159,237TotalAmt
Program Services$60,998,379ProgramServicesAmt
Management And General$8,239,241ManagementAndGeneralAmt
Fundraising$921,617FundraisingAmt

Cash Non Interest Bearing CashNonInterestBearingGrp

FieldValueIRS element (for citing)
BOY$1,667BOYAmt
EOY$0EOYAmt

Savings And Temp Cash Invst SavingsAndTempCashInvstGrp

FieldValueIRS element (for citing)
BOY$4,256,004BOYAmt
EOY$7,517,882EOYAmt

Pledges And Grants Receivable PledgesAndGrantsReceivableGrp

FieldValueIRS element (for citing)
BOY$10,565,755BOYAmt
EOY$14,223,696EOYAmt

Receivables From Officers Etc ReceivablesFromOfficersEtcGrp

FieldValueIRS element (for citing)
BOY$32,144BOYAmt
EOY$17,858EOYAmt

Oth Notes Loans Receivable Net OthNotesLoansReceivableNetGrp

FieldValueIRS element (for citing)
BOY$614,032BOYAmt
EOY$1,008,011EOYAmt

Prepaid Expenses Defrd Charges PrepaidExpensesDefrdChargesGrp

FieldValueIRS element (for citing)
BOY$1,298,030BOYAmt
EOY$949,703EOYAmt
FieldValueIRS element (for citing)
Land Bldg Equip Cost Or Other Bss$38,240,150LandBldgEquipCostOrOtherBssAmt
Land Bldg Equip Accum Deprec$20,489,441LandBldgEquipAccumDeprecAmt

Land Bldg Equip Basis Net LandBldgEquipBasisNetGrp

FieldValueIRS element (for citing)
BOY$6,890,783BOYAmt
EOY$17,750,709EOYAmt

Investments Pub Traded Sec InvestmentsPubTradedSecGrp

FieldValueIRS element (for citing)
BOY$13,300,004BOYAmt
EOY$9,254,602EOYAmt

Total Assets TotalAssetsGrp

FieldValueIRS element (for citing)
BOY$36,958,419BOYAmt
EOY$50,722,461EOYAmt

Accounts Payable Accr Expnss AccountsPayableAccrExpnssGrp

FieldValueIRS element (for citing)
BOY$9,643,229BOYAmt
EOY$16,281,365EOYAmt

Deferred Revenue DeferredRevenueGrp

FieldValueIRS element (for citing)
BOY$2,309,319BOYAmt
EOY$3,213,029EOYAmt

Mortg Notes Pybl Scrd Invst Prop MortgNotesPyblScrdInvstPropGrp

FieldValueIRS element (for citing)
BOY$0BOYAmt
EOY$7,738,978EOYAmt

Total Liabilities TotalLiabilitiesGrp

FieldValueIRS element (for citing)
BOY$11,952,548BOYAmt
EOY$27,233,372EOYAmt
FieldValueIRS element (for citing)
Organization Follows FASB117Yes (X)OrganizationFollowsFASB117Ind

No Donor Restriction Net Assets NoDonorRestrictionNetAssetsGrp

FieldValueIRS element (for citing)
BOY$16,604,913BOYAmt
EOY$15,627,555EOYAmt

Donor Restriction Net Assets DonorRestrictionNetAssetsGrp

FieldValueIRS element (for citing)
BOY$8,400,958BOYAmt
EOY$7,861,534EOYAmt

Total Net Assets Fund Balance TotalNetAssetsFundBalanceGrp

FieldValueIRS element (for citing)
BOY$25,005,871BOYAmt
EOY$23,489,089EOYAmt

Tot Liab Net Assets Fund Balance TotLiabNetAssetsFundBalanceGrp

FieldValueIRS element (for citing)
BOY$36,958,419BOYAmt
EOY$50,722,461EOYAmt
FieldValueIRS element (for citing)
Reconcilation Revenue Expnss-$1,516,782ReconcilationRevenueExpnssAmt
Other Changes In Net Assets$0OtherChangesInNetAssetsAmt
Method Of Accounting AccrualYes (X)MethodOfAccountingAccrualInd
Accountant Compile Or Review0AccountantCompileOrReviewInd
FS AuditedYes (1)FSAuditedInd

FS Audited Basis FSAuditedBasisGrp

FieldValueIRS element (for citing)
Separate Basis Fincl StmtYes (X)SeparateBasisFinclStmtInd
FieldValueIRS element (for citing)
Audit CommitteeYes (1)AuditCommitteeInd
Federal Grant Audit RequiredYes (1)FederalGrantAuditRequiredInd
Federal Grant Audit PerformedYes (1)FederalGrantAuditPerformedInd

Schedule A IRS990ScheduleA

FieldValueIRS element (for citing)
Medical Research OrganizationYes (X)MedicalResearchOrganizationInd

Hospital Name And Address HospitalNameAndAddressGrp

Supported Organization Name SupportedOrganizationName

FieldValueIRS element (for citing)
Business Name Line1The University of California San DiegoBusinessNameLine1Txt
FieldValueIRS element (for citing)
CitySan DiegoCityNm
State AbbreviationCAStateAbbreviationCd

Schedule B IRS990ScheduleB

Contributor Information ContributorInformationGrp

FieldValueIRS element (for citing)
ContributorRESTRICTEDContributorNum

Contributor Business Name ContributorBusinessName

FieldValueIRS element (for citing)
Business Name Line1RESTRICTEDBusinessNameLine1

Contributor US Address ContributorUSAddress

FieldValueIRS element (for citing)
Address Line1RESTRICTEDAddressLine1
Address Line2RESTRICTEDAddressLine2
CityRESTRICTEDCity
StateRESTRICTEDState
ZIP CodeRESTRICTEDZIPCode
FieldValueIRS element (for citing)
Total ContributionsRESTRICTEDTotalContributionsAmt

Schedule D IRS990ScheduleD

Buildings BuildingsGrp

FieldValueIRS element (for citing)
Other Cost Or Other Basis$92,333OtherCostOrOtherBasisAmt
Depreciation$92,333DepreciationAmt
Book Value$0BookValueAmt

Leasehold Improvements LeaseholdImprovementsGrp

FieldValueIRS element (for citing)
Other Cost Or Other Basis$7,613,303OtherCostOrOtherBasisAmt
Depreciation$4,280,642DepreciationAmt
Book Value$3,332,661BookValueAmt

Equipment EquipmentGrp

FieldValueIRS element (for citing)
Other Cost Or Other Basis$30,519,514OtherCostOrOtherBasisAmt
Depreciation$16,116,466DepreciationAmt
Book Value$14,403,048BookValueAmt

Other Land Buildings OtherLandBuildingsGrp

FieldValueIRS element (for citing)
Other Cost Or Other Basis$15,000OtherCostOrOtherBasisAmt
Book Value$15,000BookValueAmt
FieldValueIRS element (for citing)
Total Book Value Land Buildings$17,750,709TotalBookValueLandBuildingsAmt
Footnote TextYes (X)FootnoteTextInd
Total Rev Etc Audited Fincl Stmt$68,642,455TotalRevEtcAuditedFinclStmtAmt
Revenue Not Reported$0RevenueNotReportedAmt
Revenue Subtotal$68,642,455RevenueSubtotalAmt
Revenue Not Reported Fincl Stmt$0RevenueNotReportedFinclStmtAmt
Total Revenue Per Form990$68,642,455TotalRevenuePerForm990Amt
Tot Expns Etc Audited Fincl Stmt$70,159,234TotExpnsEtcAuditedFinclStmtAmt
Expenses Not Reported$0ExpensesNotReportedAmt
Expenses Subtotal$70,159,234ExpensesSubtotalAmt
Other Expenses Not Included$3OtherExpensesNotIncludedAmt
Expenses Not Rpt Fincl Stmt$3ExpensesNotRptFinclStmtAmt
Total Expenses Per Form990$70,159,237TotalExpensesPerForm990Amt

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Part X, Line 2:The Institute is subject to federal and state income taxes on unrelated business income as defined under IRC Sections 511 through 515. For each of the years ended December 31, 2019 and 2018, taxes are recorded when paid and no provision for income tax has been made. The Institute had no unrecognized tax benefits or liabilities as of December 31, 2019 and 2018.
Part XII, Line 4b - Other Adjustments:ROUNDING 3.

Schedule F IRS990ScheduleF

Account Activities Outside US AccountActivitiesOutsideUSGrp (3 entries)

RegionRegionTxtOfficesOfficesCntEmployeeEmployeeCntType Of Activities ConductedTypeOfActivitiesConductedTxtSpecific Services ProvidedSpecificServicesProvidedTxtRegion Total ExpendituresRegionTotalExpendituresAmt
Sub-Saharan Africa00Program ServicesResearch$15,298
Europe (Including Iceland & Greenland)00Program ServicesResearch$628,654
South Asia00Program ServicesResearch$106,229
FieldValueIRS element (for citing)
Subtotal Offices0SubtotalOfficesCnt
Subtotal Employees0SubtotalEmployeesCnt
Continuation Total Office0ContinuationTotalOfficeCnt
Continuation Total Employee0ContinuationTotalEmployeeCnt
Total Office0TotalOfficeCnt
Total Employee0TotalEmployeeCnt
Subtotal Spent$750,181SubtotalSpentAmt
Continuation Spent$0ContinuationSpentAmt
Total Spent$750,181TotalSpentAmt

Grants To Org Outside US GrantsToOrgOutsideUSGrp (8 entries)

RegionRegionTxtPurpose Of GrantPurposeOfGrantTxtCash GrantCashGrantAmt
Sub-Saharan AfricaRESEARCH$6,000
South AsiaRESEARCH$106,229
Europe (Including Iceland & Greenland)RESEARCH$79,219
Europe (Including Iceland & Greenland)RESEARCH$11,040
Europe (Including Iceland & Greenland) - Albania, Andorra, Austria, BelgiumRESEARCH$167,793
Europe (Including Iceland & Greenland)RESEARCH$69,938
Sub-Saharan Africa - Angola, Benin, Botswana, Burkina Faso,RESEARCH$9,298
Europe (Including Iceland & Greenland)RESEARCH$300,664
FieldValueIRS element (for citing)
Transfer To Foreign Corp0TransferToForeignCorpInd
Interest In Foreign Trust0InterestInForeignTrustInd
Foreign Corp Ownership0ForeignCorpOwnershipInd
Passive Foreign Investmest Co0PassiveForeignInvestmestCoInd
Foreign Partnership0ForeignPartnershipInd
Boycott Countries0BoycottCountriesInd

Supplemental Information Detail SupplementalInformationDetail (4 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Part I, Line 2:Detailed invoices are received, compared to budgeted subcontract amounts, and approved, prior to payment by LJI faculty. LJI may request additional detail or support for any unusual items. Additionally, scientific reports from subcontractors are received and reviewed by LJI investigators.
Part III Accounting Method:
Part I, Line 3, Column (F):Accrual method
Part II, Line 1Accrual method

Schedule I IRS990ScheduleI

FieldValueIRS element (for citing)
Grant Records MaintainedYes (1)GrantRecordsMaintainedInd

Recipient Table RecipientTable

Recipient Business Name RecipientBusinessName

FieldValueIRS element (for citing)
Business Name Line1JDRFBusinessNameLine1Txt

US Address USAddress

FieldValueIRS element (for citing)
Address Line15665 Oberline Drive Suite 106AddressLine1Txt
CitySan DiegoCityNm
State AbbreviationCAStateAbbreviationCd
ZIP92121ZIPCd
FieldValueIRS element (for citing)
Recipient EIN231907729RecipientEIN
IRC Section501(c)(3)IRCSectionDesc
Cash Grant$6,000CashGrantAmt
Purpose Of GrantTo Cure Type I DiabetesPurposeOfGrantTxt
FieldValueIRS element (for citing)
Total501c3 Org1Total501c3OrgCnt
Total Other Org0TotalOtherOrgCnt

Supplemental Information Detail SupplementalInformationDetail

FieldValueIRS element (for citing)
Form And Line ReferencePart I, Line 2:FormAndLineReferenceDesc
ExplanationLJI supports certain charities whose mission is inline with our research. This support is not in the form of grants, but rather contributions. Therefore, documentation exists over payment of contributions. Formal monitoring and selections procedures not considered necessary.ExplanationTxt

Schedule J IRS990ScheduleJ

FieldValueIRS element (for citing)
First Class Or Charter TravelYes (X)FirstClassOrCharterTravelInd
Written Policy Ref T And E ExpnssYes (1)WrittenPolicyRefTAndEExpnssInd
Substantiation RequiredYes (1)SubstantiationRequiredInd
Compensation CommitteeYes (X)CompensationCommitteeInd
Form990 Of Other OrganizationsYes (X)Form990OfOtherOrganizationsInd
Compensation SurveyYes (X)CompensationSurveyInd
Board Or Committee ApprovalYes (X)BoardOrCommitteeApprovalInd
Severance PaymentYes (1)SeverancePaymentInd
Supplemental Nonqual Rtr Plan0SupplementalNonqualRtrPlanInd
Equity Based Comp Arrngm0EquityBasedCompArrngmInd
Comp Based On Revenue Of Flng Org0CompBasedOnRevenueOfFlngOrgInd
Comp Bsd On Rev Related Orgs0CompBsdOnRevRelatedOrgsInd
Comp Bsd Net Earns Flng Org0CompBsdNetEarnsFlngOrgInd
Comp Bsd Net Earns Rltd Orgs0CompBsdNetEarnsRltdOrgsInd
Any Non Fixed Payments0AnyNonFixedPaymentsInd
Initial Contract Exception0InitialContractExceptionInd

Rltd Org Officer Trst Key Empl RltdOrgOfficerTrstKeyEmplGrp (10 entries)

TitleTitleTxtBase Compensation Filing OrgBaseCompensationFilingOrgAmtCompensation Based On Rltd OrgsCompensationBasedOnRltdOrgsAmtBonus Filing OrganizationBonusFilingOrganizationAmountBonus Related OrganizationsBonusRelatedOrganizationsAmtOther Compensation Filing OrgOtherCompensationFilingOrgAmtOther Compensation Rltd OrgsOtherCompensationRltdOrgsAmtDeferred Compensation Flng OrgDeferredCompensationFlngOrgAmtDeferred Comp Rltd OrgsDeferredCompRltdOrgsAmtNontaxable Benefits Filing OrgNontaxableBenefitsFilingOrgAmtNontaxable Benefits Rltd OrgsNontaxableBenefitsRltdOrgsAmtTotal Compensation Filing OrgTotalCompensationFilingOrgAmtTotal Compensation Rltd OrgsTotalCompensationRltdOrgsAmtComp Report Prior990 Filing OrgCompReportPrior990FilingOrgAmtComp Report Prior990 Rltd OrgsCompReportPrior990RltdOrgsAmt
Mitchell Kronenberg
President & CSO$513,979$0$0$0$27,785$0$61,000$0$24,071$0$626,835$0$0$0
Michael Dollar
CFO (Start 06/24/2019)$125,923$0$0$0$21,063$0$0$0$13,682$0$160,668$0$0$0
Stephen Wilson
EVP, COO & CTO$366,469$0$0$0$20,393$0$60,225$0$37,810$0$484,897$0$0$0
Michael Croft
Director Scientific Affairs$319,939$0$0$0$3,237$0$48,750$0$22,482$0$394,408$0$0$0
Alessandro Sette
Division Head/Center Head/Prof$403,175$0$0$0$22,241$0$61,000$0$35,752$0$522,168$0$0$0
Catherine Hedrick
Professor$307,584$0$0$0$17,526$0$46,892$0$21,291$0$393,293$0$0$0
Klaus Ley
Division Head/Professor$311,770$0$0$0$4,759$0$46,933$0$12,044$0$375,506$0$0$0
Stephen P Schoenberger
Professor$285,092$0$0$0$3,241$0$46,717$0$35,752$0$370,802$0$0$0
Hilde Cheroutre
Division Head/Professor$289,399$0$0$0$4,603$0$43,606$0$12,018$0$349,626$0$0$0
Jennifer K Keyes
CFO (End 06/18/2019)$120,847$0$0$0$95,014$0$15,073$0$6,138$0$237,072$0$0$0

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Part I, Line 1aThe President/Chief Scientific Officer took one first class business related flight which was in accordance with LJI Policy. No amount was treated as taxable to the listed person.
Part II, Line 10Jennifer K. Keyes, former, CFO, received a severance payment of $85,833 in 2019.

Schedule L IRS990ScheduleL

Loans Btwn Org Interested Prsn LoansBtwnOrgInterestedPrsnGrp

Business Name BusinessName

FieldValueIRS element (for citing)
Business Name Line1SEE PART VBusinessNameLine1Txt
FieldValueIRS element (for citing)
Loan From OrganizationYes (X)LoanFromOrganizationInd
Original Principal$100,000OriginalPrincipalAmt
Balance Due$17,858BalanceDueAmt
Default0DefaultInd
Board Or Committee ApprovalYes (1)BoardOrCommitteeApprovalInd
Written AgreementYes (1)WrittenAgreementInd
FieldValueIRS element (for citing)
Total Balance Due$17,858TotalBalanceDueAmt

Bus Tr Involve Interested Prsn BusTrInvolveInterestedPrsnGrp

Name Of Interested NameOfInterested

Business Name BusinessName

FieldValueIRS element (for citing)
Business Name Line1SEE PART VBusinessNameLine1Txt
FieldValueIRS element (for citing)
Sharing Of Revenues0SharingOfRevenuesInd

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Sch L, Part II, Loans to and / or From Interested Persons:(a) Name of Person: Catherine Hedrick(b) Relationship Between Interested Person and Organization:Highest Compensated Employee(c) Purpose of Loan: Faculty Housing Loan(d) Loan to or From the Organization: From(e) Original Principal Amount $100,000(f) Balance Due: $17,858(g) In Default: No(h) Approved by board or Committee: Yes(i) Written Agreement: Yes
Sch L, Part IV, Business Transactions Involving Interested Persons:(a) Name of Person: Hilde Cheroutre(b) Relationship Between Interested Person and Organization: Spouse of President and CSO (c) Amount of Transaction: $294,002(d) Description of Transaction: Full Time Employee(e) Sharing of Organization Revenues?: No(a) Name of Person: Kyowa Kirin Pharmaceutical Research, Inc.(b) Relationship Between Interested Person and Organization:KKR is a Substantial Contributor to the Organization.(c) Amount of Transaction: $3,326,659(d) Description of Transaction: Research Funding, Facility Rent, Cost Reimbursements (e) Sharing of Organization Revenues?: No

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (7 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Form 990, Part III, Line 4a;Dr. Erica Ollmann Saphire, one of the world's leading experts in pandemic and emerging viruses, joined LJI faculty in the spring of 2019. Dr. Saphire directs an international consortium analyzing antibody therapeutics and vaccine responses. Her lab studies the three-dimensional structures of viral proteins to understand, at the molecular level, how viruses like Ebola, Marburg and Lassa are so deadly. In a series of groundbreaking discoveries, her team has determined the molecular structures of the Ebola, Sudan, Bundibugyo, Marburg, LCMV and Lassa virus surface glycoproteins; how these viruses suppress immune function and where human antibodies dock to defeat these viruses. A widely recognized structural biologist, Dr. Saphire has established a molecular imaging facility at La Jolla Institute for cryo-electron microscopy (cryo-EM). The extremely detailed images produced by cryo-EM reveal precisely how essential mechanisms of the immune system operate. Bringing Dr. Saphire's expertise and state-of-the-art cryo-EM capabilities to the Institute will help LJI scientists drive pioneering advances from molecular structure to human immunology to global health. Among the flood of research papers published by scientists and scholars in academic journals year in and year out, by some estimates their numbers now exceed 2,500,000 papers annually; the research contributions of scientists at La Jolla Institute for Immunology stand out for their global impact. Four researchers, or 19 percent of La Jolla Institute for Immunology's faculty, have been named in the Highly Cited Researchers 2019 list from the Web of Science Group. The 2019 Highly Cited Researchers list, released November 19 by the Web of Science Group, identifies scientists who produced multiple papers ranking in the top 1% by citations for their field and year of publication, demonstrating significant research influence among their peers. La Jolla Institute for Immunology faculty on the list include Professor Shane Crotty, Ph.D., whose ground breaking work on the immunology underlying vaccines earned him a spot on the list for the fourth year in a row; Professor Alessandro Sette, Dr. Biol.Sci., whose sustained efforts to systematically dissect the immune response to a wide range of microbes and allergens has a tremendous impact on the field of immunology, made the list for the second year. This year, they are joined by Professor Bjoern Peters, Ph.D., who helped established the Immune Epitope Database, a free, searchable site that houses data from more than 1.6 million experiments, making it a one-stop shop for understanding and predicting the body's response to viruses, bacteria, cancer, allergens and more, and Professor Anjana Rao, Ph.D., whose pioneering insights into the fundamentals of T cell biology have the potential to successfully address T cell exhaustion, which, in the past, has limited the success of cancer immunotherapies. In 2019, professors Crotty and Sette were named as Fellows of the American Association for the Advancement of Science (AAAS). Election as an AAAS Fellow is an honor bestowed upon AAAS members by their peers. Dr. Crotty was elected an AAAS fellow in recognition of his distinguished contributions to the field of vaccine immunology, particularly defining and characterizing T follicular helper (Tfh) cells and their roles in humoral immunity. Dr. Sette was recognized for his distinguished contributions to the field of immunology, particularly for providing insights into T-cell specificity and immune-profiling of T-cells in human disease, and for pioneering immuno-informatics. Dr. Crotty also was selected to receive the 2019 Frederick W. Alt Award for New Discoveries in Immunology for his pioneering insights in the fundamentals of what makes a good immune response to help custom-engineer vaccine candidates so they elicit a protective immune response. The award is given annually to a former Cancer Research Institute postdoctoral fellow in recognition of outstanding success in academia or industry for research that has had a major impact in the field of immunology. The American Association of Immunologists (AAI) has named LJI President and Chief Scientific Officer Dr. Mitchell Kronenberg, a world expert in T cell biology, as an AAI 2019 Distinguished Fellow. He is among 52 immunologists, including five Nobel Laureates, selected for the inaugural class of fellows. Election as a Distinguished Fellow is among the highest honors bestowed by AAI and recognizes members for distinguished careers and outstanding scientific contributions as well as their service to AAI and the immunology community. Dr. Kronenberg is best known for his extensive studies of a subset of specialized T cells known as invariant natural killer T (iNKT) cells and their brethren, mucosal-associated invariant T (MAIT) cells. Both cell types are an integral part of the innate immune response, which reacts almost immediately to foreign invaders. Sara McArdle, Ph.D., a microscopy specialist at La Jolla Institute for Immunology (LJI) who helps scientists take advantage of the latest imaging technology by bridging the gap between engineering, software development, data processing and biology, was selected as one of seventeen "Imaging Scientists" by the Chan Zuckerberg Initiative (CZI). CZI initiated the Imaging Scientists program to break down the walls between disciplines and empower biologists to reap the most benefit from new technical advances in the field of imaging. It funds imaging specialists who can move creatively between different fields, from physics and medicine, to engineering and biology. In 2019, La Jolla Institute for Immunology (LJI) has been awarded a $22 million contract renewal over seven years from the National Institutes of Health (NIH) to host and expand the Immune Epitope Database (IEDB). The database is the world's most comprehensive collection of scientific data on how the immune system responds to a wide range of infectious agents, allergy-causing substances, and other stimuli that activate the immune system. A La Jolla Institute-led consortium was awarded up to $35 million by the National Institutes of Health. It brings together experts from around the world to streamline and accelerate the development of immunotherapeutics against emerging and re-emerging viral threats under the leadership of Dr. Saphire. The Viral Immunotherapeutic Consortium (VIC) continues a tremendously successful international program that Dr. Saphire initiated and directed to bridge the gap between results obtained in the lab and effective treatments that can be deployed in the field. The consortium, now headquartered at La Jolla Institute for Immunology, will specifically focus on the clinical development of therapeutic candidates identified by the VIC for Ebola and other related filoviruses, arenaviruses, such as Lassa virus as well as a third major global threat, alphaviruses, which infect millions of people across the world. 2019 Notable Research Results In 2019, LJI research teams made discoveries meriting publication in leading peer-reviewed scientific journals 147 papers in all, continuing a trend of very high productivity. 45 of them appeared in high impact journals, which is a measure of the research's pioneering nature and influence. Together, they illustrate the range and power of immunology research, the caliber of LJI's faculty and their impact on a broad group of human health issues. Some of the highlights among papers published in 2019 include: Dr. Crotty showed that new HIV vaccine delivery strategy appears to enhance the protective immune response in a preclinical model. He and his colleagues discovered that delivering an HIV vaccine in small doses over a series of days leads to a stronger immune response than when the same vaccine is given all at once. A similar escalating dose method could be the best way to administer an HIV vaccine in future clinical trials. In an unrelated study, Dr. Crotty and his team discovered why some kids are prone to repeated bouts of strep throat while others appear to be more or less immune. His findings suggest that recurrent tonsillitis is a multifactorial disease where immunological factors combined with an underlying genetic susceptibility allow group A strep to invade the throats of certain individuals time and again. Gaining a better understanding of why some children fail to develop protective immunity also opens the door to developing a vaccine to protect against strep throat, the researchers predict.
Form 990, Part III, Line 4a;Dr. Anjana Rao and her team devised a strategy to counteract T cell exhaustion in CAR T cancer therapies. A growing number of cancer patients are being offered a promising new treatment called CAR T cell therapy. In this therapy, a patients' own T cells are removed and genetically engineered to better recognize cancer cells. The cells are then returned to the patient's body, where they can mount an immune response. CAR T-cell therapies have saved lives, but there has been a downside: T cells can get overstimulated over time and can stop working due to a phenomenon called T cell exhaustion. The scientists' new study shows that a family of proteins, called Nr4a transcription factors, have a prominent role in regulating the genes associated with T cell exhaustion. Using a mouse model, the scientists demonstrated that treating mice with CAR T cells lacking these Nr4a transcription factors led to smaller tumors and better survival. Dr. Saphire and her team revealed Lassa virus' soft spot. CAAs this year's Lassa fever outbreak in Nigeria is finally ebbing, the total tally came to more than 600 infected people, one-quarter of them dead. Thousands more die each year, uncounted in rural villages throughout West Africa. With an annual wave of infections and new viral strains emerging, it has never been more important to understand the characteristics of a broadly protective immune response in order to develop effective treatments, or better yet, a vaccine. A new study led by Instructor Kathryn Hastie, Ph.D., and Professor Erica Ollmann Saphire, Ph.D., identified and then reverse engineered the molecular properties shared by antibodies that are particularly efficient at inactivating or "neutralizing" the virus. The team's findings also revealed that most neutralizing antibodies bind to the same spot on the surface of Lassa virus, providing a map for rational vaccine design. A study by Dr. Pandurangan Vijayanand identified a type of T cell that possesses superior tumor killing potential. Immunotherapies hold promise as a way to prompt a patient's own immune system to fight cancer cells. Yet immunotherapies only work in about 30 percent of patientsand they can cause dangerous side effects. In their new study, LJI scientists collaborated with a team from the University of Southampton to better understand a group of immune cells called tissue-resident memory T cells (TRMs). These cells are known to help the body fight infection, but there is increasing evidence that they also play a key role in fighting tumors. According to the new Journal of Experimental Medicine study, published in the June 21, 2019 edition, TRMs are indeed key tumor fighters. These cells are unique for their ability to seek out and kill tumor cells without suffering from the common phenomenon of T cell "exhaustion." Competitive Research Grant Funding & Research Awards & Distinctions During 2019, LJI scientists worked with the support of hundreds of grants, contracts and fellowships. The granting or prime institutions included: AbViro, American Association for Cancer Research, American Diabetes Association, American Heart Association, Bill & Melinda Gates Foundation, Boston Children's Hospital, Cancer Research Institute, Celsense, Chan Zuckerberg Initiative, CIRM, Columbia University, Crohn's and Colitis Foundation, Cue BioPharma, Eli Lilly, Emergent, Evotec, Expres2ion fund, Gritstone, Human Vaccines Project, Icahn School of Medicine at Mount Sinai, Incyte Corporation, Jane Coffin Childs, Kiowa Kirin Pharmaceuticals Research Inc., Lurie Children's Hospital of Chicago, Lyell Immunopharma, Michael J. Fox Foundation, Nektar Therapeutics, Neon Therapeutics, Novo Nordisk, Ondek, Parker Institute, Pew Charitable Trust, Pfizer, RythRx Therapeutics, SBP Medical Discovery Institute, Scripps Research Institute, Takeda, Tremeau Pharmaceuticals, Tulane University, Turnstone, Ukko Inc., Umea University/EU Commission, University of Oxford, University of California Berkeley, University of California Los Angeles, University of California Riverside, University of California San Diego, University of Pennsylvania, University of Virginia, Vanderbilt University, Vasculitis Foundation, Washington University, St Louis, Zalgen, AALAS, Albert Einstein College of Medicine, American Association of Immunologists, Bristol-Myers Squibb, Cedars Sinai Medical Center, Chicago Biosolutions, Emory University, Flow Pharma, Integrated Biotherapeutics, International AIDS Vaccine Initiative, iTeos Therapeutics, Leukemia & Lymphoma Society, Medical College of Wisconsin/Doris Duke Charitable Foundation, Moores Cancer Center, National Institute for Biotechnology, National Institutes of Health, Naval Medical Research Center, Oregon University, Quality Biological, Inc., Regeneron Pharmaceuticals, Inc, University of Washington With new and recurring grant support, the Institute received more than $54 million in research funding in 2019, which is supplemented by corporate funding sources as well as philanthropic support.
Form 990, Part VI, Section A, line 2Mitchell Kronenberg, Ph.D. and Hilde Cheroutre have a family relationship.
Form 990, Part VI, Section B, line 11bIn accordance with written Institute Policy, a draft of Form 990 is provided to all Board Members for their review and comment approximately 10 days prior to filing. This provides an opportunity for members of the Board to ask questions and obtain additional information. Comments and suggested changes to the draft are incorporated into the final version of Form 990.
Form 990, Part VI, Section B, line 12cThe Institute administers three separate conflict of interest policies applying to 1) The Board of Directors, 2) Faculty and Senior Administration, and 3) An investigator financial conflict of interest policy required under National Institutes of Health Regulations. The Institute regularly and consistently monitors and enforces these policies in accordance with written procedures, which include the completion of disclosure forms by covered individuals, evaluation of completed forms by a designated conflict review officer, and as necessary, further evaluation and determination by a designated conflict review committee. If a conflict is determined, a management plan is designed and monitored for the specific situation. Such plan may require the covered individual to eliminate the conflict.
Form 990, Part VI, Section B, line 15Compensation decisions for the institute's CEO and other key employees are made annually. Adjustments, if any, typically take effect on a January 1st Cycle. For these purposes, the institute's Human Resources Department Obtains relevant market comparability data for each position on an annual Basis. The institute also periodically engages an independent compensation Consulting firm to perform compensation studies for key individuals and to Evaluate the institute's executive compensation and benefits programs for Reasonableness. In accordance with its charter, the compensation committee Of the board of directors reviews and discusses this information, and the Performance of the institute's CEO and key employees, and formulates Recommended compensation actions to the full board of directors. The board Of directors reviews these recommendations and related information in Deciding compensation levels for each position.
Form 990, Part VI, Section C, line 19The Institute makes its governing documents, Conflict of Interest Policy, and Financial Statements available to the public upon request. Summarized Financial data is also made available as part of the Institute's Annual Report, which is widely distributed, and can be downloaded from the Institute's web site.

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