NATIONAL TUBEROUS SCLEROSIS ASSOCIATION INC: Form 990, tax year 2021

View the entire original 990 at ProPublica ↗

Organization: NATIONAL TUBEROUS SCLEROSIS ASSOCIATION INC (EIN 95-3018799)
Tax period: 2021-01-01 to 2021-12-31
Filed: 2022-04-11
IRS object ID: 202241019349300349
Schema version: 2021v4.2
Source: Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header
Form 990
Schedule A
Schedule B
Schedule C
Schedule D
Schedule F
Schedule G
Schedule I
Schedule J
Schedule M
Schedule O
Schedule R

Return header ReturnHeader

Field	Value	IRS element (for citing)
Return	2022-04-11T17:00:01-05:00	ReturnTs
Tax Period End	2021-12-31	TaxPeriodEndDt

Preparer Firm PreparerFirmGrp

Field	Value	IRS element (for citing)
Preparer Firm EIN	420714325	PreparerFirmEIN

Preparer Firm Name PreparerFirmName

Field	Value	IRS element (for citing)
Business Name Line1	RSM US LLP	BusinessNameLine1Txt

Preparer US Address PreparerUSAddress

Field	Value	IRS element (for citing)
Address Line1	2021 L STREET NW SUITE 400	AddressLine1Txt
City	WASHINGTON	CityNm
State Abbreviation	DC	StateAbbreviationCd
ZIP	20036	ZIPCd

Field	Value	IRS element (for citing)
Return Type	990	ReturnTypeCd
Tax Period Begin	2021-01-01	TaxPeriodBeginDt

Filer Filer

Field	Value	IRS element (for citing)
EIN	953018799	EIN

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	NATIONAL TUBEROUS SCLEROSIS ASSOCIATION	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Business Name Control	NATI	BusinessNameControlTxt
Phone	3015629890	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	8737 COLESVILLE ROAD 400	AddressLine1Txt
City	SILVER SPRING	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20910	ZIPCd

Business Officer BusinessOfficerGrp

Field	Value	IRS element (for citing)
Person	KARI L ROSBECK	PersonNm
Person Title	PRESIDENT & CEO	PersonTitleTxt
Phone	3015629890	PhoneNum
Signature	2022-04-08	SignatureDt
Discuss With Paid Preparer	Yes (1)	DiscussWithPaidPreparerInd

Signing Officer SigningOfficerGrp

Person Full Name PersonFullName

Field	Value	IRS element (for citing)
Person First	KARI	PersonFirstNm
Person Last	ROSBECK	PersonLastNm

Field	Value	IRS element (for citing)
SSN	XXX-XX-XXXX	SSN

Preparer Person PreparerPersonGrp

Field	Value	IRS element (for citing)
Preparer Person	ELIZABETH W HELLER	PreparerPersonNm
PTIN	P00397829	PTIN
Phone	2022932200	PhoneNum
Preparation	2022-04-08	PreparationDt

Additional Filer Information AdditionalFilerInformation

Trusted Customer TrustedCustomerGrp

Field	Value	IRS element (for citing)
Trusted Customer	3	TrustedCustomerCd
Authentication Assurance Level	AAL1	AuthenticationAssuranceLevelCd
Identity Assurance Level	IAL1	IdentityAssuranceLevelCd

Field	Value	IRS element (for citing)
Tax	2021	TaxYr
Build TS	2022-09-23 18:48:47Z	BuildTS

Form 990 IRS990

Doing Business As Name DoingBusinessAsName

Field	Value	IRS element (for citing)
Business Name Line1	TSC ALLIANCE	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Principal Officer	KARI L ROSBECK	PrincipalOfficerNm

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	8737 COLESVILLE ROAD 400	AddressLine1Txt
City	SILVER SPRING	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20910	ZIPCd

Field	Value	IRS element (for citing)
Gross Receipts	$9,061,703	GrossReceiptsAmt
Group Return For Affiliates	0	GroupReturnForAffiliatesInd
Organization501c3	Yes (X)	Organization501c3Ind
Website Address	WWW.TSCALLIANCE.ORG	WebsiteAddressTxt
Type Of Organization Corp	Yes (X)	TypeOfOrganizationCorpInd
Formation	1975	FormationYr
Legal Domicile State	CA	LegalDomicileStateCd
Activity Or Mission	FINDING A CURE FOR TUBEROUS SCLEROSIS COMPLEX WHILE IMPROVING THE LIVES OF THOSE AFFECTED.	ActivityOrMissionDesc
Voting Members Governing Body	29	VotingMembersGoverningBodyCnt
Voting Members Independent	29	VotingMembersIndependentCnt
Total Employee	22	TotalEmployeeCnt
Total Volunteers	2234	TotalVolunteersCnt
Total Gross UBI	$0	TotalGrossUBIAmt
Net Unrelated Bus Txbl Incm	$0	NetUnrelatedBusTxblIncmAmt
PY Contributions Grants	$4,345,011	PYContributionsGrantsAmt
CY Contributions Grants	$5,769,053	CYContributionsGrantsAmt
PY Program Service Revenue	$792,685	PYProgramServiceRevenueAmt
CY Program Service Revenue	$2,234,262	CYProgramServiceRevenueAmt
PY Investment Income	$11,770	PYInvestmentIncomeAmt
CY Investment Income	$5,670	CYInvestmentIncomeAmt
PY Other Revenue	-$21,302	PYOtherRevenueAmt
CY Other Revenue	$1,007,002	CYOtherRevenueAmt
PY Total Revenue	$5,128,164	PYTotalRevenueAmt
CY Total Revenue	$9,015,987	CYTotalRevenueAmt
PY Grants And Similar Paid	$685,788	PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid	$948,236	CYGrantsAndSimilarPaidAmt
PY Benefits Paid To Members	$0	PYBenefitsPaidToMembersAmt
CY Benefits Paid To Members	$0	CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid	$2,382,792	PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid	$2,455,940	CYSalariesCompEmpBnftPaidAmt
PY Total Prof Fndrsng Expns	$0	PYTotalProfFndrsngExpnsAmt
CY Total Prof Fndrsng Expns	$0	CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense	$886,523	CYTotalFundraisingExpenseAmt
PY Other Expenses	$2,353,610	PYOtherExpensesAmt
CY Other Expenses	$3,465,386	CYOtherExpensesAmt
PY Total Expenses	$5,422,190	PYTotalExpensesAmt
CY Total Expenses	$6,869,562	CYTotalExpensesAmt
PY Revenues Less Expenses	-$294,026	PYRevenuesLessExpensesAmt
CY Revenues Less Expenses	$2,146,425	CYRevenuesLessExpensesAmt
Total Assets BOY	$11,657,873	TotalAssetsBOYAmt
Total Assets EOY	$14,046,866	TotalAssetsEOYAmt
Total Liabilities BOY	$2,195,312	TotalLiabilitiesBOYAmt
Total Liabilities EOY	$2,437,880	TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY	$9,462,561	NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY	$11,608,986	NetAssetsOrFundBalancesEOYAmt
Info In Schedule O Part III	Yes (X)	InfoInScheduleOPartIIIInd
Mission	THE NATIONAL TUBEROUS SCLEROSIS ASSOCIATION, D/B/A TSC ALLIANCE, IS DEDICATED TO FINDING A CURE FOR TUBEROUS SCLEROSIS COMPLEX WHILE IMPROVING THE LIVES OF THOSE AFFECTED.	MissionDesc
Significant New Program Srvc	0	SignificantNewProgramSrvcInd
Significant Change	0	SignificantChangeInd
Expense	$3,939,485	ExpenseAmt
Grant	$948,236	GrantAmt
Revenue	$3,190,730	RevenueAmt
Desc	RESEARCH PROGRAM STIMULATES AND SUPPORTS BASIC, TRANSLATIONAL, AND CLINICAL RESEARCH ON THE VARIOUS MANIFESTATIONS OF TUBEROUS SCLEROSIS COMPLEX (TSC) TO FURTHER THE DEVELOPMENT OF CLINICAL THERAPIES AND, ULTIMATELY, A CURE FOR TSC. DIRECTED BY STEVEN L. ROBERDS, PHD, CHIEF SCIENTIFIC OFFICER, THE TSC ALLIANCE RESEARCH PROGRAM BUILDS AND FOSTERS COLLABORATIONS BETWEEN BASIC AND CLINICAL RESEARCHERS BY COLLECTING AND DISTRIBUTING TSC NATURAL HISTORY DATA AND BIOSAMPLES, THROUGH COLLABORATIVE PRECLINICAL AND CLINICAL RESEARCH PROGRAMS, AND BY HOSTING BIENNIAL INTERNATIONAL TSC RESEARCH CONFERENCES.SINCE 1984, THE TSC ALLIANCE HAS INVESTED $31 MILLION INTO TSC RESEARCH PROJECTS THROUGH GRANTS AND CONTRACTS: $19.5 MILLION IN RESEARCH GRANTS AND POSTDOCTORAL FELLOWSHIPS, $4.6 MILLION INTO THE NATURAL HISTORY DATABASE AND BIOSAMPLE REPOSITORY, $5.9 MILLION INTO THE PRECLINICAL CONSORTIUM, AND $0.95 MILLION INTO THE CLINICAL RESEARCH CONSORTIUM. GRANT AND FELLOWSHIP APPLICATIONS ARE REVIEWED IN A THREE-STEP PROCESS: (1) ALL APPLICATIONS ARE REVIEWED BY A COMMITTEE COMPRISED OF SCIENTISTS KNOWLEDGEABLE ABOUT THE TOPIC AREA FOR SCIENTIFIC MERIT AND OF CAREGIVERS OR ADULTS AFFECTED BY TSC FOR POTENTIAL IMPACT ON THE LIVES OF THOSE AFFECTED BY TSC; (2) THE SCIENCE AND MEDICAL COMMITTEE OF THE BOARD OF DIRECTORS EVALUATES THE GRANT REVIEW COMMITTEE'S RECOMMENDATIONS AND THE RELEVANCE OF THE APPLICATIONS TO THE TSC ALLIANCE'S FUNDING PRIORITIES; AND (3) THE BOARD OF DIRECTORS THEN REVIEWS THE RECOMMENDATIONS OF THE SCIENCE AND MEDICAL COMMITTEE AND MAKES FINAL APPROVAL FOR FUNDING. FOR A COMPLETE LIST OF CURRENTLY FUNDED PROJECTS AND AN ARCHIVE OF PAST AWARDEES, PLEASE VISIT TSCALLIANCE.ORG/GRANTS.IMPLEMENTED IN 2006, THE TSC NATURAL HISTORY DATABASE (NHD) CAPTURES CLINICAL DATA TO DOCUMENT THE IMPACT OF THE DISEASE ON A PERSON'S HEALTH OVER THEIR LIFETIME. THE DATABASE SERVES AS A RESOURCE OF INFORMATION THAT HELPS TSC RESEARCHERS BETTER UNDERSTAND THE PROGRESSION OF THE DISEASE, DESIGN HYPOTHESIS-DRIVEN QUESTIONS TO HASTEN THE DISCOVERY OF NEW TREATMENTS AND IDENTIFY PERSONS WITH TSC WHO ARE ELIGIBLE TO PARTICIPATE IN RESEARCH STUDIES. AS OF DECEMBER 2021, 2,357 PEOPLE WITH TSC WERE ENROLLED IN THE PROJECT FROM AMONG 18 U.S.-BASED SITES AND THROUGH THE TSC ALLIANCE. THE TSC ALLIANCE PROVIDES FUNDING TO PARTICIPATING CLINICS TO PERFORM DATA ENTRY, MONITORS THE INTEGRITY OF THE DATABASE, AND MAKES DATA AVAILABLE TO INVESTIGATORS TO ANSWER SPECIFIC RESEARCH QUESTIONS AND IDENTIFY POTENTIAL PARTICIPANTS FOR CLINICAL TRIALS AND STUDIES. IN 2020, THE TSC ALLIANCE ADDED A COVID-19 SUB-PROJECT TO ADDRESS DETAILED QUESTIONS ABOUT COVID-19 INFECTION IN INDIVIDUALS WITH TSC. FOR THIS PROJECT, THE TSC ALLIANCE OPENED THIS NHD SUB-PROJECT UP TO PARTICIPANTS WITH SPORADIC LYMPHANGIOLEIOMYOMATOSIS (S-LAM) IN PARTNERSHIP WITH THE LAM FOUNDATION. IN 2021, THE TSC ALLIANCE EXPANDED THE SUB-PROJECT'S VARIABLES TO INCLUDE ENTRIES FOR COVID-19 VACCINATIONS AND ANTIBODY TESTS. BUILDING UPON THE NATURAL HISTORY DATABASE, THE TSC BIOSAMPLE REPOSITORY IS A TSC ALLIANCE-DIRECTED PROJECT INITIATED IN 2014 THAT WILL IMPACT RESEARCH OVER THE NEXT 10 YEARS OR MORE. THE TSC ALLIANCE'S SCIENCE AND MEDICAL COMMITTEE IDENTIFIED THIS AS A GAP THAT CAN ONLY BE FILLED EFFECTIVELY WITH LEADERSHIP OF THE TSC ALLIANCE, GUIDED BY A STEERING COMMITTEE OF CLINICIANS AND RESEARCHERS. HIGH-QUALITY BIOSAMPLES SUCH AS BLOOD, DNA, AND TISSUES LINKED TO DETAILED CLINICAL DATA ARE CRITICAL FOR RESEARCHERS TO UNDERSTAND WHY TSC IS SO DIFFERENT FROM PERSON TO PERSON. SAMPLES IN THE REPOSITORY ARE LINKED TO DETAILED CLINICAL DATA IN OUR EXISTING TSC NATURAL HISTORY DATABASE AND ARE AVAILABLE TO QUALIFIED RESEARCHERS WORLDWIDE. SAMPLES ARE HOUSED AT AND DISTRIBUTED FROM THE VAN ANDEL INSTITUTE IN GRAND RAPIDS, MI, UNDER CONTROL OF THE TSC ALLIANCE. AS OF DECEMBER 31, 2021, THE TSC BIOSAMPLE REPOSITORY HAS ACQUIRED 2,000 BIOSAMPLES: 615 BLOOD SAMPLES FROM INDIVIDUALS WITH TSC ENROLLED IN THE NHD, 367 BUCCAL SAMPLES FROM INDIVIDUALS WITH TSC ENROLLED IN THE NHD, 154 TISSUE SAMPLES FROM INDIVIDUALS WITH TSC ENROLLED IN THE NHD, 465 BLOOD SAMPLES FROM THE TSC CLINICAL RESEARCH CONSORTIUM COLLABORATIVE PROJECTS, AND 389 DNA SAMPLES FROM THE TSC AUTISM CENTER OF EXCELLENCE NETWORK AUTISM BIOMARKER STUDY. THE ORGANIZATION CONTINUES TO GROW THE BIOSAMPLE REPOSITORY BY COLLECTING BLOOD SAMPLES ANNUALLY FROM PARTICIPANTS WHO VOLUNTEER TO DO SO, ENABLING RESEARCHERS TO STUDY CHANGES IN PROTEINS AND OTHER MOLECULES IN THE BLOOD OVER TIME; ADDING ADDITIONAL TSC CLINICS AS PARTICIPATING BIOSAMPLE REPOSITORY COLLECTION SITES; AND COLLECTING BLOOD USING MOBILE PHLEBOTOMY, ENABLING PEOPLE TO DONATE SAMPLES REGARDLESS OF WHERE THEY LIVE IN THE US AND WHETHER THEY ARE SEEN AT A TSC CLINIC. SINCE THE INCEPTION OF OUR MOBILE PHLEBOTOMY INITIATIVE, WE HAVE ACQUIRED 187 BLOOD SAMPLES VIA MOBILE PHLEBOTOMY. UNIQUE ADDITIONS IN 2021 INCLUDED THE ACQUISITION OF 100 TISSUES FROM THE MARYLAND BRAIN AND TISSUE BANK, FIVE CORD BLOOD SAMPLES FROM INFANTS WITHOUT TSC TO USE AS CONTROLS IN FUTURE EXPERIMENTS FOR THE NEWBORN SCREENING INITIATIVE, AND ONE CORD BLOOD SAMPLE FROM AN INDIVIDUAL WITH TSC. TO ENCOURAGE AND ENABLE MORE RESEARCHERS TO UTILIZE BIOSAMPLES, THE TSC ALLIANCE FUNDED THREE SEED GRANTS IN 2021, TOTALING $54,940.80, TO LABS THAT SUBMITTED MERITORIOUS AND INNOVATIVE IDEAS FOR RESEARCH ON TSC BIOSAMPLES.IN 2021, THE TSC ALLIANCE COMPLETED A WHOLE-GENOME SEQUENCING (WGS) PILOT STUDY USING DNA FROM BLOOD SAMPLES IN OUR BIOSAMPLE REPOSITORY TO DEMONSTRATE THE FEASIBILITY OF THIS APPROACH. THE TSC ALLIANCE SUBMITTED 20 DNA SAMPLES WHICH HAD NOT BEEN PREVIOUSLY ANALYZED TO THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (TGEN) FOR WGS. RESULTS REVEALED DISEASE-CAUSING VARIANTS IN 19 OF 20 SAMPLES AND DEMONSTRATED FEASIBILITY OF WGS TO DELIVER VALUABLE INFORMATION TO BOTH PATIENTS AND RESEARCHERS. WE INTEND TO SCALE UP WGS IN COMING YEARS AS FUNDS ARE RAISED FOR THIS INITIATIVE.IN DECEMBER 2021, THE TSC ALLIANCE ADDED THE TSC SELF-REPORT PORTAL TO THE TSC NATURAL HISTORY DATABASE. THIS NEW PORTAL WILL PERMIT THE COLLECTION OF PATIENT-REPORTED OUTCOMES ON HOW TSC AFFECTS INDIVIDUALS AND FAMILIES, WHICH WILL COMPLEMENT MEDICAL DATA IN THE NATURAL HISTORY DATABASE. THE PURPOSE OF THIS INITIATIVE IS TO HELP THE TSC ALLIANCE AND TSC RESEARCHERS BETTER UNDERSTAND THE PERSPECTIVE OF THOSE AFFECTED BY TSC TO DEVELOP TOOLS TO MEASURE IMPROVEMENT IN AREAS MOST IMPORTANT TO THE TSC COMMUNITY. EVENTUALLY, THESE MEASUREMENTS CAN BE USED TO IDENTIFY ENDPOINTS FOR CLINICAL TRIALS AND EVIDENCE-BASED GUIDELINES FOR TREATMENT.ONE OF THE MOST IMPACTFUL ASPECTS OF TSC ON THE QUALITY OF LIFE FOR PEOPLE LIVING WITH TSC IS TSC-ASSOCIATED NEUROPSYCHIATRIC DISORDERS (TAND). THEREFORE, THE TSC ALLIANCE'S FIRST USE OF THE PORTAL IS THROUGH COLLABORATION WITH THE TANDEM PROJECT (EMPOWERING FAMILIES THROUGH TECHNOLOGY: A MOBILE-HEALTH PROJECT TO REDUCE THE TAND IDENTIFICATION AND TREATMENT GAP) BY ALLOWING THE COMMUNITY TO COMPLETE THE SELF-QUANTIFIED TAND CHECKLIST (TAND-SQ). THE TSC ALLIANCE IS HELPING THE TANDEM PROJECT TEAM VALIDATE THE UTILITY OF THE TAND-SQ FOR FUTURE USE IN A MOBILE APPLICATION.THE TSC ALLIANCE LAUNCHED THE TSC PRECLINICAL CONSORTIUM IN 2015 TO HELP ADVANCE MORE DRUG CANDIDATES INTO CLINICAL TESTING. TO ACHIEVE THIS END, THE PRECLINICAL CONSORTIUM PROVIDES THE INFRASTRUCTURE TO FOSTER COLLABORATION BETWEEN ACADEMIA AND PHARMACEUTICAL INDUSTRY RESEARCHERS AND FOR ACCESS TO RESOURCES DESIGNED TO HELP FACILITATE DRUG DEVELOPMENT IN TSC. COLLABORATING WITH THE TSC COMMUNITY, THE CONSORTIUM HAS IDENTIFIED AND IMPLEMENTED ROBUST AND REPRODUCIBLE CELL AND ANIMAL MODELS FOR TSC MANIFESTATIONS INCLUDING TUMORS, EPILEPSY, AND TAND. THE TSC ALLIANCE HAS LICENSES TO USE SPECIFIC TSC MOUSE MODELS FOR EXPERIMENTS CARRIED OUT BY THE PRECLINICAL CONSORTIUM, AND ALL MOUSE LICENSE AGREEMENTS INCLUDE THE RIGHTS FOR THE TSC ALLIANCE TO PERFORM EXPERIMENTS UNDER CONTRACT FOR COMMERCIAL ENTITIES. THIS ENSURES DATA GENERATED BY THE PRECLINICAL CONSORTIUM CAN BE USED TO ACCELERATE THE DEVELOPMENT OF NEW TREATMENTS BY COMMERCIAL ENTITIES AS WELL AS ACADEMIC INVESTIGATORS. EXPERIMENTS ARE EXECUTED AT PARTNERING RESEARCH INSTITUTIONS TO ENSURE CONSISTENCY IN TESTING, DATA ACQUISITION AND INTERPRETATION. EPILEPSY STUDIES ARE CONDUCTED AT PSYCHOGENICS (US), AND THE TUMOR GRAFT MODEL AND CELL-BASED ASSAYS ARE CONDUCTED AT PORSOLT (FRANCE). THE VAN ANDEL RESEARCH INSTITUTE, A NON-PROFIT RESEARCH ORGANIZATION, MAINTAINS A COLONY OF TSC2+/- AJ MICE AND BREEDING PAIRS OF L7-CRE-TSC2 MICE ON BEHALF OF THE PRECLINICAL CONSORTIUM.	Desc

Prog Srvc Accom Acty2 ProgSrvcAccomActy2Grp

Field	Value	IRS element (for citing)
Expense	$648,010	ExpenseAmt
Grant	$0	GrantAmt
Revenue	$183,500	RevenueAmt
Desc	SUPPORT SERVICES DEVELOPS PROGRAMS AND SERVICES THAT PROVIDE INDIVIDUALS WITH TSC DIRECT ACCESS TO INFORMATION, RESOURCES, AND SPECIALISTS EXPERIENCED IN THE DIAGNOSIS, TREATMENT AND MANAGEMENT OF TSC. IN 2021 THE TSC ALLIANCE FACILITATED 8,742 PEER-TO-PEER SUPPORTS FROM ADULT REGIONAL COORDINATORS (12 VOLUNTEERS IN 8 REGIONS NATIONWIDE), CLINIC AMBASSADORS (16 VOLUNTEERS IN 19 TSC CLINICS AND TSC CENTERS OF EXCELLENCE NATIONWIDE), DEPENDENT ADULT TRANSITION RESOURCE COORDINATORS (31 VOLUNTEERS IN 26 STATES AND PUERTO RICO), EDUCATION PARENT MENTORS (29 VOLUNTEERS IN 21 STATES), AND COMMUNITY ALLIANCE LEADERS (47 VOLUNTEERS IN 33 REGIONS ACROSS THE UNITED STATES) WITH ACTIVE FUTURE LEADERS (8 VOLUNTEERS) AND PAST FUTURE LEADERS (6 VOLUNTEERS) WHO HAVE AGREED TO REMAIN AS LEADERS FOR OTHER YOUNG ADULTS WITH TSC.EDUCATION PARENT MENTORS ATTENDED 55 SCHOOL MEETINGS (IEPS, EVALUATION TEAM MEETINGS, 504 PLAN MEETINGS, RESOLUTION MEETINGS, AND MEDIATIONS) IN PERSON, THROUGH SKYPE/ZOOM, AND VIA CONFERENCE CALLS TO SUPPORT FAMILIES IN ATTAINING EDUCATIONAL SERVICES FOR THEIR CHILDREN THROUGHOUT THE COUNTRY. SEVERAL SCHOOL SYSTEMS ALSO REQUESTED "TSC 101" IN AN EFFORT TO HELP THEM UNDERSTAND THE COMPLEXITIES OF TSC AND LEARNING ISSUES FOR CHILDREN WITH TSC. THE COMMUNITY PROGRAMS TEAM SUPPORTS A NETWORK OF 33 VOLUNTEER BRANCHES OF THE ORGANIZATION, CALLED COMMUNITY ALLIANCES, THAT PROVIDE SUPPORT AND COMMUNITY EDUCATION IN ALL 50 STATES. TO ENSURE THE TSC COMMUNITY CONTINUE TO RECEIVE UPDATED INFORMATION ABOUT TSC, TSC-ASSOCIATED NEUROPSYCHIATRIC DISORDERS (TAND),TRANSITION AND RESEARCH, THE TSC ALLIANCE DEVELOPED AN E-WEBINAR SERIES. IN 2021, WE HOSTED 27 E-WEBINARS WITH 1,219 CUMULATIVE LIVE ATTENDEES, 5,567 CUMULATIVE RECORDING VIEWS AND 3,123 CUMULATIVE LANDING PAGES VISITS. ADDITIONALLY, WE HELD THE FOLLOWING WEBINARS: APRIL COVID VACCINE TOWN HALL - 66 LIVE ATTENDEES, 304 VIDEO VIEWS; ABC TO SAP WEBINAR - 50 LIVE ATTENDEES, 458 VIDEO VIEWS; AUGUST COVID UPDATE TOWN HALL - 307 LIVE ATTENDEES, 463 VIDEO VIEWS. ADDING IN LIVE ATTENDEES WITH ADDITIONAL WEBINARS TOTAL LIVE AUDIENCE FOR WEBINARS IS 1,642, TOTAL CUMULATIVE RECORDING VIEWS IS 6,636 AND 3,123 CUMULATIVE LANDING PAGE VISITS.IN 2021, THE TSC ALLIANCE LAUNCHED THE TSC NAVIGATOR, AN EASY-TO-USE, INTERACTIVE ONLINE TOOL TO HELP GUIDE INDIVIDUALS AND FAMILIES THROUGH THE COMPLEXITIES OF TSC ACROSS THE LIFESPAN, PROACTIVELY MANAGE THEIR CARE, AND LIVE THEIR FULLEST LIVES. USERS CAN ACCESS INFORMATION BASED ON THE AGE OF ONE'S DIAGNOSIS, SUCH AS PRENATAL, CHILDHOOD, OR ADULT, TO HELP DETERMINE WHICH STEPS WILL HELP EMPOWER THEM THROUGHOUT THEIR INDIVIDUAL JOURNEYS. REGARDLESS OF AGE, TSC NAVIGATOR ALSO HELPS INDIVIDUALS WITH TSC AND THEIR CAREGIVERS FACE COMPLEX SITUATIONS, OVERCOME ACCESS ISSUES, AND ADDRESS INSURANCE BARRIERS. THE TSC NAVIGATOR LAUNCHED OCTOBER 14, 2019 AND RECEIVED MORE THAN 2,700 VISITS BETWEEN LAUNCH AND YEAR END.587 INDIVIDUALS AND FAMILIES WERE ASSISTED DIRECTLY BY THE DIRECTOR OF MEDICAL AFFAIRS AND TEAM ACTING AS SUPPORT NAVIGATORS. OF THE ASSISTANCE PROVIDED, 78 WERE MEDICATION-RELATED, 60 WERE TAND-RELATED, 88 WERE NEW DIAGNOSIS, AND 252 WERE FOR ASSISTANCE WITH ACCESS TO CARE WITH 46 COVID-19 RELATED. THE REMAINDER SERVED A VARIETY OF OTHER NEEDS.	Desc

Prog Srvc Accom Acty3 ProgSrvcAccomActy3Grp

Field	Value	IRS element (for citing)
Expense	$524,283	ExpenseAmt
Grant	$0	GrantAmt
Revenue	$69,500	RevenueAmt
Desc	PUBLIC HEALTH EDUCATION HEIGHTENS AWARENESS OF TSC THROUGHOUT THE GENERAL PUBLIC TO BROADEN THE SCOPE OF SUPPORT AND UNDERSTANDING BEYOND TSC INDIVIDUALS AND THEIR FAMILIES. ONE MAJOR PROJECT IN 2021 WAS CHANGING THE ORGANIZATION'S NAME TO TSC ALLIANCE, WHICH WAS FORMALLY ANNOUNCED SUNDAY, MAY 16.DURING 2021, THE TSC ALLIANCE ALSO PRODUCED TWO ISSUES OF ITS NATIONAL MAGAZINE, PERSPECTIVE, WHICH IS MAILED TO APPROXIMATELY 17,900 CONSTITUENTS AS WELL AS POSTED ON THE WEBSITE. THE TSC ALLIANCE'S PODCAST SERIES, CALLED TSC NOW, PRODUCED 12 EPISODES WITH 2,186 DOWNLOADS. SIX ISSUES OF THE ELECTRONIC TSC MATTERS NEWSLETTER WERE DISTRIBUTED TO 1,340 SUBSCRIBERS. THE TSC ALLIANCE'S WEBSITE INCREASES AWARENESS AND PROVIDES EXTENSIVE EDUCATION THROUGH AN AVERAGE OF MORE THAN 24,000 UNIQUE VISITORS EACH MONTH. THE TSC ALLIANCE ALSO RELIES HEAVILY ON SOCIAL MEDIA TO EDUCATE CONSTITUENTS AND PROMOTE NEW RESOURCES AND EVENTS. ITS PRIVATE FACEBOOK TSC DISCUSSION GROUP BOASTS MORE THAN 10,000 MEMBERS, WHILE ITS TWITTER ACCOUNT HAS 2,579 FOLLOWERS AND INSTAGRAM HAS 2,762 FOLLOWERS. TO INCREASE PUBLIC AWARENESS, THE TSC ALLIANCE PARTICIPATED IN THE SEVENTH ANNUAL TSC GLOBAL AWARENESS DAY ON MAY 15 AS WELL AS TSC AWARENESS MONTH THROUGHOUT MAY. THE TSC ALLIANCE ALSO HEAVILY PROMOTED THE INAUGURAL SEIZURE ACTION PLAN AWARENESS WEEK (FEBRUARY 8-14) AND INFANTILE SPASMS AWARENESS WEEK (DECEMBER 1 TO 7). THESE AWARENESS CAMPAIGNS ALONG WITH THE ORGANIZATIONS VARIOUS NEWS RELEASES CULMINATED IN MORE THAN 1 BILLION CUMULATIVE IMPRESSIONS.	Desc

Prog Srvc Accom Acty Other ProgSrvcAccomActyOtherGrp

Field	Value	IRS element (for citing)
Expense	$353,569	ExpenseAmt
Revenue	$34,070	RevenueAmt
Desc	GOVERNMENT RELATIONS EFFORTS FOCUS ON INCREASING FEDERAL AND STATE APPROPRIATIONS FOR TSC RESEARCH, RAISING AWARENESS, AND COLLABORATING WITH GOVERNMENT PARTNERS TO DRIVE TSC RESEARCH FORWARD AND IMPROVE CLINICAL CARE AND TREATMENT OPTIONS FOR INDIVIDUALS WITH TSC. ON THE STATE LEVEL, THE TSC ALLIANCE ADVOCATED FOR STATE FUNDING FOR TSC CENTERS IN MISSOURI AND MARYLAND, RESULTING IN AT LEAST $750,000 IN STATE APPROPRIATIONS. THE ANNUAL TSC ALLIANCE MARCH ON CAPITOL HILL TO ADVOCATE FOR FEDERAL FUNDING FOR THE TUBEROUS SCLEROSIS COMPLEX RESEARCH PROGRAM (TSCRP) AT THE DEPARTMENT OF DEFENSE'S (DOD) CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAM (CDMRP) TOOK PLACE IN EARLY MARCH 2021. MORE THAN 135 PEOPLE PARTICIPATED IN THE VIRTUAL MARCH ON CAPITOL HILL THE WEEK OF MARCH 1-5, 2021. ADVOCATES MADE VIRTUAL APPOINTMENTS WITH 75 SENATE AND 280 HOUSE OFFICES TO ADVOCATE FOR A CONTINUATION OF $8 MILLION IN FUNDING FOR THE TSCRP. THE HOUSE TSCRP DEAR COLLEAGUE LETTER SPONSORED BY REPRESENTATIVES MULLIN (R-OK) AND RASKIN (D-MD) CLOSED WITH 202 SIGNERS. THE SENATE LETTER SPONSORED BY SENATORS CRAMER (R-ND) AND HEINRICH (D-NM) CLOSED WITH 34 SIGNERS. TOTAL FUNDING FOR THE TSCRP HAS BEEN $105 MILLION SINCE 2002. PRESIDENT BIDEN JUST SIGNED THE FY22 DEFENSE BILL INTO LAW ON MARCH 15, 2022, WHICH INCLUDED $8 MILLION FOR THE TSCRP.RESEARCH PERFORMED THROUGH THIS PROGRAM HAS RECENTLY LED TO ADDITIONAL CLINICAL TRIALS INCLUDING DETERMINING IF IMATINIB, A DRUG FDA-APPROVED FOR CANCER, CAN SAFELY IMPROVE LEVELS OF VEGF-D, A BIOMARKER OF LYMPHANGIOLEIOMYOMATOSIS (LAM), A LIFE-THREATENING LUNG MANIFESTATION OF TSC, FUNDED IN FY2013; TESTING A COMBINATION OF TWO DRUGS TO TREAT LAM FUNDED IN FY2012; A MULTI-SITE CLINICAL TRIAL TESTING THE EFFICACY OF AN EXPERIMENTAL TOPICAL RAPAMYCIN CREAM TO TREAT THE DISFIGURING FACIAL TUMORS, CALLED FACIAL ANGIOFIBROMAS, CAUSED BY TSC FUNDED IN FY2010; A CLINICAL RESEARCH NETWORK WAS CREATED TO TEST POTENTIAL NEW THERAPIES, TO VALIDATE BIOMARKERS, AND TO LEARN THE NATURAL HISTORY OF LEADING TO A CLINICAL TRIAL FUNDED IN FY2012. DATA OBTAINED FROM AN FY2010 TSCRP CLINICAL RESEARCH AWARD TO DEFINE EARLY AUTISM PREDICTORS IN TSC AND AN FY2014 TSCRP AWARD FOR A PILOT CLINICAL TRIAL IS BEING TESTED IN A LARGE, NIH-FUNDED CLINICAL TRIAL LOOKING AT THE EFFECTIVENESS OF A BEHAVIORAL INTERVENTION STRATEGY, JASPER, TO IMPROVE OUTCOMES IN CHILDREN WITH AUTISM. THE TSCRP HAS ALSO FUNDED RESEARCH TO DEVELOP ANIMAL MODELS OF TSC THAT HAVE SEIZURES, ENABLING A BETTER UNDERSTANDING OF THE ETIOLOGY OF TSC. BASED ON DATA FROM TSCRP-FUNDED ANIMAL MODELS OF TSC THAT HAVE SEIZURES AND SHARE PATHOLOGY RELATED TO THAT OF TRAUMATIC BRAIN INJURY, AN INDUSTRY-SPONSORED CLINICAL TRIAL DEMONSTRATED THE EFFECTIVENESS THE MTOR INHIBITOR, EVEROLIMUS, AT TREATING EPILEPSY IN MANY INDIVIDUALS WITH TSC. NONE OF THIS PROGRESS WOULD HAVE BEEN POSSIBLE WITHOUT THE CRITICAL SUPPORT PROVIDED THROUGH THE TSCRP.GLOBAL OUTREACH WORKS TO ADDRESS UNMET NEEDS WITHIN THE GLOBAL TSC COMMUNITY. THE PROGRAM PROVIDES THE OPPORTUNITY FOR THE TSC ALLIANCE TO SHARE EXPERIENCES AND ASSIST IN THE START-UP OF SUPPORT OF TSC-RELATED ORGANIZATIONS IN OTHER COUNTRIES. A GLOBAL ALLIANCE IS A STRUCTURED GROUP OF EMPOWERED AND CARING VOLUNTEERS WHO WORK CLOSELY WITH THE TSC ALLIANCE TO FACILITATE LOCAL CONNECTIONS FOR INDIVIDUALS AND FAMILIES AFFECTED BY TSC AND RAISE REVENUE AND AWARENESS WHILE SUPPORTING THE MISSION OF THE ORGANIZATION. THE TSC ALLIANCE HAS SIX GLOBAL PARTNERSHIPS, INCLUDING: TSC ALLIANCE OF ISRAEL, TS CANADA ST, TSC ALLIANCE OF MEXICO, TSC ALLIANCE FOUNDATION (IN THAILAND), HUNGARIAN FOUNDATION FOR TUBEROUS SCLEROSIS, AND TSC ALLIANCE OF INDIA. THE TSC ALLIANCE RECOGNIZES 10 TSC CLINICS IN GLOBAL ALLIANCE COUNTRIES. PROFESSIONAL EDUCATION EXPANDS PROGRAMS TO TARGET RESEARCHERS AND HEALTHCARE PROVIDERS CARING FOR INDIVIDUALS WITH TSC, MEDICAL STUDENTS, GENETIC COUNSELORS AND EDUCATORS TO MINIMIZE THE CONSEQUENCES OF IGNORANCE AND MISINFORMATION. IN AUGUST, TWO NEW PUBLICATIONS WERE ACCEPTED BY PEDIATRIC NEUROLOGY, "UPDATED INTERNATIONAL TSC DIAGNOSTIC CRITERIA AND SURVEILLANCE AND MANAGEMENT RECOMMENDATIONS AND "BEYOND THE GUIDELINES: HOW WE CAN IMPROVE HEALTHCARE FOR PEOPLE WITH TSC AROUND THE WORLD." THE NEW PAPERS PROVIDE THE FIRST SIGNIFICANT UPDATES TO THE INTERNATIONAL GUIDELINES SINCE 2013 BECAUSE OF NEW MEDICATIONS AND ADVANCES IN TREATMENTS. TO ADDRESS THE CHANGES, A WORKING GROUP LED BY DARCY A. KRUEGER, MD, PHD, OF CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER, AND HOPE NORTHRUP, MD, MCGOVERN MEDICAL SCHOOL, UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON, INCLUDED 80 PARTICIPANTS FROM 16 COUNTRIES.THE TSC ALLIANCE PARTICIPATED IN OR PRESENTED AT 37 PROFESSIONAL MEETINGS IN 2021 INCLUDING CURING THE EPILEPSIES 2020: SETTING RESEARCH PRIORITIES, NIMH 2021 VIRTUAL WORKSHOP: GENE-BASED THERAPEUTICS FOR RARE NEURODEVELOPMENTAL PSYCHIATRIC DISORDERS, TSC ALLIANCE: NEWBORN SCREENING WORKSHOP, ATS BOARD OF DIRECTORS MEETING, RARE DISEASE DAY AT NIH, ISAN MEMBERSHIP MEETING, INAUGURAL O'DONNELL BRAIN INSTITUTE SYMPOSIUM ON AUTISM SPECTRUM DISORDERS, OVERCOMING BARRIERS TO DIVERSIFYING CLINICAL TRIALS (RDCRN), ELHS SPRING LEARNING SESSION, HEALTH RESEARCH ALLIANCE CULTURAL COMPETENCY WORKSHOP WITH BME, RESEARCH!AMERICA ANNUAL MEETING OF THE MEMBERS, MEDICAID AND CHIP PAYMENT AND ACCESS COMMISSION (MACPAC) WEBINAR, ICARE MEETING, TRANS-NIH MEETING, ATS PAR MEET-THE-EXPERTS PATIENT/FAMILY FORUM, ATS SCIENTIFIC SYMPOSIUM, USF DIVERSITY, EQUITY, AND INCLUSION IN THE WORKPLACE SERIES, ISAN MEMBERSHIP MEETING-SUMMER, GLOBAL GENES RARE DRUG DEVELOPMENT SYMPOSIUM: PRECLINICAL MODELING-WHAT ADVOCATES NEED TO KNOW ABOUT ANIMAL & CELL MODELS, INTERNATIONAL TSC RESEARCH CONFERENCE-UK, RARE DISEASE PATIENT-FOCUSED DRUG DEVELOPMENT (PFDD) GUIDANCE COMPENDIUM, GLOBAL GENES ACCESS WORKING GROUP LUNCH BRIEFING: MEDICAID COVERAGE FOR GENOMIC SEQUENCING, NINDS NONPROFIT FORUM ADVISORY BOARD MEETING-INDUSTRY PARTNER, GLOBAL GENES: ACCESS WORKING GROUP, LGS FOUNDATION MEETING OF THE MINDS, EVERYLIFE VIRTUAL NEWBORN SCREENING BOOTCAMP, CNF SYMPOSIUM (WITHIN CNS), RDCRN FALL MEETING, NIAMS, BIO, VIRTUAL INTERNATIONAL TSC & LAM RESEARCH CONFERENCE, ATS PAR ANNUAL PLANNING MEETING, TSCI VIRTUAL WORKSHOP, TSCRP PROGRAMMATIC REVIEW & VISION SETTING, AMERICAN EPILEPSY SOCIETY ANNUAL MEETING, AND INFANTILE SPASMS ACTION NETWORK MEMBERS MEETING.	Desc

Field	Value	IRS element (for citing)
Total Other Prog Srvc Expense	$353,569	TotalOtherProgSrvcExpenseAmt
Total Other Prog Srvc Revenue	$34,070	TotalOtherProgSrvcRevenueAmt
Total Program Service Expenses	$5,465,347	TotalProgramServiceExpensesAmt
Described In Section501c3	Yes (1)	DescribedInSection501c3Ind
Schedule B Required	Yes (1)	ScheduleBRequiredInd
Political Campaign Acty	0	PoliticalCampaignActyInd
Lobbying Activities	Yes (1)	LobbyingActivitiesInd
Subject To Proxy Tax	0	SubjectToProxyTaxInd
Donor Advised Fund	0	DonorAdvisedFundInd
Conservation Easements	0	ConservationEasementsInd
Collections Of Art	0	CollectionsOfArtInd
Credit Counseling	0	CreditCounselingInd
Donor Rstr Or Quasi Endowments	Yes (1)	DonorRstrOrQuasiEndowmentsInd
Report Land Building Equipment	Yes (1)	ReportLandBuildingEquipmentInd
Report Investments Other Sec	0	ReportInvestmentsOtherSecInd
Report Program Related Invst	0	ReportProgramRelatedInvstInd
Report Other Assets	Yes (1)	ReportOtherAssetsInd
Report Other Liabilities	Yes (1)	ReportOtherLiabilitiesInd
Include FIN48 Footnote	0	IncludeFIN48FootnoteInd
Independent Audit Fincl Stmt	0	IndependentAuditFinclStmtInd
Consolidated Audit Fincl Stmt	Yes (1)	ConsolidatedAuditFinclStmtInd
School Operating	0	SchoolOperatingInd
Foreign Office	0	ForeignOfficeInd
Foreign Activities	Yes (1)	ForeignActivitiesInd
More Than5000 K To Org	Yes (1)	MoreThan5000KToOrgInd
More Than5000 K To Individuals	0	MoreThan5000KToIndividualsInd
Professional Fundraising	0	ProfessionalFundraisingInd
Fundraising Activities	Yes (1)	FundraisingActivitiesInd
Gaming Activities	0	GamingActivitiesInd
Operate Hospital	0	OperateHospitalInd
Grants To Organizations	Yes (1)	GrantsToOrganizationsInd
Grants To Individuals	0	GrantsToIndividualsInd
Schedule J Required	Yes (1)	ScheduleJRequiredInd
Tax Exempt Bonds	0	TaxExemptBondsInd
Engaged In Excess Benefit Trans	0	EngagedInExcessBenefitTransInd
PY Excess Benefit Trans	0	PYExcessBenefitTransInd
Loan Outstanding	0	LoanOutstandingInd
Grant To Related Person	0	GrantToRelatedPersonInd
Business Rln With Org Mem	0	BusinessRlnWithOrgMemInd
Business Rln With Fam Mem	0	BusinessRlnWithFamMemInd
Business Rln With35 Ctrl Ent	0	BusinessRlnWith35CtrlEntInd
Deductible Non Cash Contri	Yes (1)	DeductibleNonCashContriInd
Deductible Art Contribution	0	DeductibleArtContributionInd
Terminate Operations	0	TerminateOperationsInd
Partial Liquidation	0	PartialLiquidationInd
Disregarded Entity	0	DisregardedEntityInd
Related Entity	Yes (1)	RelatedEntityInd
Related Organization Ctrl Ent	0	RelatedOrganizationCtrlEntInd
Trnsfr Exmpt Non Chrtbl Rltd Org	0	TrnsfrExmptNonChrtblRltdOrgInd
Activities Conducted Prtshp	0	ActivitiesConductedPrtshpInd
Schedule O Required	Yes (1)	ScheduleORequiredInd
IRP Document	31	IRPDocumentCnt
IRP Document W2 G	0	IRPDocumentW2GCnt
Backup Wthld Compliance	Yes (1)	BackupWthldComplianceInd
Employee	22	EmployeeCnt
Employment Tax Returns Filed	Yes (1)	EmploymentTaxReturnsFiledInd
Unrelated Bus Incm Over Limit	0	UnrelatedBusIncmOverLimitInd
Foreign Financial Account	0	ForeignFinancialAccountInd
Prohibited Tax Shelter Trans	0	ProhibitedTaxShelterTransInd
Taxable Party Notification	0	TaxablePartyNotificationInd
Nondeductible Contributions	0	NondeductibleContributionsInd
Quid Pro Quo Contributions	Yes (1)	QuidProQuoContributionsInd
Quid Pro Quo Contri Discl	Yes (1)	QuidProQuoContriDisclInd
Form8282 Property Disposed Of	0	Form8282PropertyDisposedOfInd
Rcv Fnds To Pay Prsnl Bnft Cntrct	0	RcvFndsToPayPrsnlBnftCntrctInd
Pay Premiums Prsnl Bnft Cntrct	0	PayPremiumsPrsnlBnftCntrctInd
Indoor Tanning Services	0	IndoorTanningServicesInd
Subj To Tax Rmnrtn Ex Prcht Pymt	0	SubjToTaxRmnrtnExPrchtPymtInd
Subject To Excs Tax Net Invst Inc	0	SubjectToExcsTaxNetInvstIncInd
Info In Schedule O Part VI	Yes (X)	InfoInScheduleOPartVIInd
Governing Body Voting Members	29	GoverningBodyVotingMembersCnt
Independent Voting Member	29	IndependentVotingMemberCnt
Family Or Business Rln	0	FamilyOrBusinessRlnInd
Delegation Of Mgmt Duties	0	DelegationOfMgmtDutiesInd
Change To Org Documents	0	ChangeToOrgDocumentsInd
Material Diversion Or Misuse	0	MaterialDiversionOrMisuseInd
Members Or Stockholders	Yes (1)	MembersOrStockholdersInd
Election Of Board Members	Yes (1)	ElectionOfBoardMembersInd
Decisions Subject To Approva	0	DecisionsSubjectToApprovaInd
Minutes Of Governing Body	Yes (1)	MinutesOfGoverningBodyInd
Minutes Of Committees	Yes (1)	MinutesOfCommitteesInd
Officer Mailing Address	0	OfficerMailingAddressInd
Local Chapters	Yes (1)	LocalChaptersInd
Policies Reference Chapters	Yes (1)	PoliciesReferenceChaptersInd
Form990 Provided To Gvrn Body	Yes (1)	Form990ProvidedToGvrnBodyInd
Conflict Of Interest Policy	Yes (1)	ConflictOfInterestPolicyInd
Annual Disclosure Covered Prsn	Yes (1)	AnnualDisclosureCoveredPrsnInd
Regular Monitoring Enfrc	Yes (1)	RegularMonitoringEnfrcInd
Whistleblower Policy	Yes (1)	WhistleblowerPolicyInd
Document Retention Policy	Yes (1)	DocumentRetentionPolicyInd
Compensation Process CEO	Yes (1)	CompensationProcessCEOInd
Compensation Process Other	Yes (1)	CompensationProcessOtherInd
Investment In Joint Venture	0	InvestmentInJointVentureInd
States Where Copy Of Return Is Fld	AL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	AR	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	CA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	FL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	GA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	HI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	IL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	IN	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	KS	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	KY	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MD	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MN	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MS	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NH	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NJ	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NM	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NY	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NC	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	OR	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	PA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	RI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	SC	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	TN	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	UT	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	VA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	WI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	WV	StatesWhereCopyOfReturnIsFldCd
Own Website	Yes (X)	OwnWebsiteInd
Other Website	Yes (X)	OtherWebsiteInd
Upon Request	Yes (X)	UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	THE ORGANIZATION	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Phone	3015629890	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	8737 COLESVILLE ROAD 400	AddressLine1Txt
City	SILVER SPRING	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20910	ZIPCd

Form990 Part VII Section A Form990PartVIISectionAGrp (37 entries)

TitleTitleTxt	Average Hours Per WeekAverageHoursPerWeekRt	Average Hours Per Week Rltd OrgAverageHoursPerWeekRltdOrgRt	Individual Trustee Or DirectorIndividualTrusteeOrDirectorInd	OfficerOfficerInd	Reportable Comp From OrgReportableCompFromOrgAmt	Reportable Comp From Rltd OrgReportableCompFromRltdOrgAmt	Other CompensationOtherCompensationAmt	Key EmployeeKeyEmployeeInd	Highest Compensated EmployeeHighestCompensatedEmployeeInd
PETER CRINO MD PHD
CHAIR	5.00	0.00	Yes (X)	Yes (X)	$0	$0	$0
WILLIAM JOSEPH
VICE CHAIR	5.00	1.00	Yes (X)	Yes (X)	$0	$0	$0
CHRIS RUSSELL
IMMEDIATE PAST CHAIR	5.00	0.00	Yes (X)	Yes (X)	$0	$0	$0
LAURA MARKS
SECRETARY	5.00	0.00	Yes (X)	Yes (X)	$0	$0	$0
PAUL WAXLAX
TREASURER	5.00	1.00	Yes (X)	Yes (X)	$0	$0	$0
DEREK BAUER
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
JULIE BLUM
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
MATT BOLGER
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
EDWARD BURKHALTER
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
MARK CARROLL
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
SARAH CHIEFFO
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
DAVID COIT
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
MARGARET COX
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
TIMOTHY DILLS
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
BONNIE HOGUE DUFFY
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
TANJALA GIPSON
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
STEVEN GOLDSTEIN
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
ROBERT GRANDIA
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
DANA HOLINKA
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
JESSICA KREFTING
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
DARCY KRUEGER
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
HEATHER LENS
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
JIM MAGINN
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
DIANE MCSWAIN
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
MUSTAFA SAHIN
BOARD MEMBER	2.00	1.00	Yes (X)		$0	$0	$0
SEAN SHILLINGER
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
MATTHEW SIMONIAN
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
VANESSA VAZQUEZ
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
TARA ZIMMERMAN
BOARD MEMBER	2.00	0.00	Yes (X)		$0	$0	$0
KARI L ROSBECK
PRESIDENT & CEO	54.00	1.00		Yes (X)	$214,608	$3,974	$33,232
RICHARD GOLLUB
CFO	47.00	3.00		Yes (X)	$156,734	$10,004	$32,878
STEVEN L ROBERDS
CHIEF SCIENTIFIC OFFICER	45.00	0.00			$228,854	$0	$26,998	Yes (X)
DEAN RAGER-AGUIAR
DIRECTOR, PRECLINICAL RESEARCH	45.00	0.00			$163,695	$0	$32,110	Yes (X)
JAYE D ISHAM
VP, COMMUNICATIONS STRATEGY	45.00	0.00			$121,765	$0	$4,244		Yes (X)
LISA M MOSS
SR. DIRECTOR, DONOR RELATIONS	45.00	0.00			$109,646	$0	$26,893		Yes (X)
APRIL COOPER
DIRECTOR, COMMUNITY PROGRAMS	45.00	0.00			$108,589	$0	$3,418		Yes (X)
ASHLEY POUNDERS
DIRECTOR, MEDICAL AFFAIRS	45.00	0.00			$101,208	$0	$11,671		Yes (X)

Field	Value	IRS element (for citing)
Total Reportable Comp From Org	$1,205,099	TotalReportableCompFromOrgAmt
Tot Reportable Comp Rltd Org	$13,978	TotReportableCompRltdOrgAmt
Total Other Compensation	$171,444	TotalOtherCompensationAmt
Indiv Rcvd Greater Than100 K	8	IndivRcvdGreaterThan100KCnt
Former Ofcr Employees Listed	0	FormerOfcrEmployeesListedInd
Total Comp Greater Than150 K	Yes (1)	TotalCompGreaterThan150KInd
Compensation From Other Srcs	0	CompensationFromOtherSrcsInd

Contractor Compensation ContractorCompensationGrp (3 entries)

Address Line1ContractorAddress/USAddress/AddressLine1Txt	CityContractorAddress/USAddress/CityNm	State AbbreviationContractorAddress/USAddress/StateAbbreviationCd	ZIPContractorAddress/USAddress/ZIPCd	ServicesServicesDesc	CompensationCompensationAmt
PSYCHOGENICS INC
20 GRAMERCY PARK SOUTH	NEW YORK	NY	10003	RESEARCH LAB SERVICES	$1,564,533
VAN ANDEL RESEARCH INSTITUTE
333 BOSTWICK AVE NE	GRAND RAPIDS	MI	49503	LABORATORY SERVICES	$227,915
CAVAROCCHI RUSCIO DENNIS AND ASSOCIATES
600 MARYLAND AVE SW	WASHINGTON	DC	20024	GOVERNMENT RELATIONS	$112,980

Field	Value	IRS element (for citing)
Cntrct Rcvd Greater Than100 K	3	CntrctRcvdGreaterThan100KCnt
Federated Campaigns	$50,596	FederatedCampaignsAmt
Membership Dues	$4,132	MembershipDuesAmt
Fundraising	$955,330	FundraisingAmt
Related Organizations	$226,000	RelatedOrganizationsAmt
All Other Contributions	$4,532,995	AllOtherContributionsAmt
Noncash Contributions	$285,267	NoncashContributionsAmt
Total Contributions	$5,769,053	TotalContributionsAmt

Program Service Revenue ProgramServiceRevenueGrp (2 entries)

DescDesc	BusinessBusinessCd	Total Revenue ColumnTotalRevenueColumnAmt	Related Or Exempt Func IncomeRelatedOrExemptFuncIncomeAmt
CONTRACT REVENUE	900099	$2,120,485	$2,120,485
CONFERENCE REVENUE	900099	$113,777	$113,777

Field	Value	IRS element (for citing)
Total Program Service Revenue	$2,234,262	TotalProgramServiceRevenueAmt

Investment Income InvestmentIncomeGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$3,809	TotalRevenueColumnAmt
Exclusion	$3,809	ExclusionAmt

Gross Amount Sales Assets GrossAmountSalesAssetsGrp

Field	Value	IRS element (for citing)
Securities	$1,861	SecuritiesAmt

Less Cost Oth Basis Sales Expnss LessCostOthBasisSalesExpnssGrp

Field	Value	IRS element (for citing)
Securities	$0	SecuritiesAmt

Gain Or Loss GainOrLossGrp

Field	Value	IRS element (for citing)
Securities	$1,861	SecuritiesAmt

Net Gain Or Loss Investments NetGainOrLossInvestmentsGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$1,861	TotalRevenueColumnAmt
Exclusion	$1,861	ExclusionAmt

Field	Value	IRS element (for citing)
Fundraising Gross Income	$234,482	FundraisingGrossIncomeAmt
Contri Rpt Fundraising Event	$955,330	ContriRptFundraisingEventAmt
Fundraising Direct Expenses	$45,716	FundraisingDirectExpensesAmt

Net Incm From Fundraising Evt NetIncmFromFundraisingEvtGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$188,766	TotalRevenueColumnAmt
Exclusion	$188,766	ExclusionAmt

Other Revenue Misc OtherRevenueMiscGrp

Field	Value	IRS element (for citing)
Desc	CHANGE INT-ENDOWMENT	Desc
Business	900099	BusinessCd
Total Revenue Column	$818,236	TotalRevenueColumnAmt
Exclusion	$818,236	ExclusionAmt

Field	Value	IRS element (for citing)
Other Revenue Total	$818,236	OtherRevenueTotalAmt

Total Revenue TotalRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$9,015,987	TotalRevenueColumnAmt
Related Or Exempt Func Income	$2,234,262	RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue	$0	UnrelatedBusinessRevenueAmt
Exclusion	$1,012,672	ExclusionAmt

Grants To Domestic Orgs GrantsToDomesticOrgsGrp

Field	Value	IRS element (for citing)
Total	$833,329	TotalAmt
Program Services	$833,329	ProgramServicesAmt

Foreign Grants ForeignGrantsGrp

Field	Value	IRS element (for citing)
Total	$114,907	TotalAmt
Program Services	$114,907	ProgramServicesAmt

Comp Current Ofcr Directors CompCurrentOfcrDirectorsGrp

Field	Value	IRS element (for citing)
Total	$797,701	TotalAmt
Program Services	$489,000	ProgramServicesAmt
Management And General	$223,016	ManagementAndGeneralAmt
Fundraising	$85,685	FundraisingAmt

Other Salaries And Wages OtherSalariesAndWagesGrp

Field	Value	IRS element (for citing)
Total	$1,242,312	TotalAmt
Program Services	$792,478	ProgramServicesAmt
Management And General	$103,838	ManagementAndGeneralAmt
Fundraising	$345,996	FundraisingAmt

Other Employee Benefits OtherEmployeeBenefitsGrp

Field	Value	IRS element (for citing)
Total	$275,780	TotalAmt
Program Services	$173,018	ProgramServicesAmt
Management And General	$38,279	ManagementAndGeneralAmt
Fundraising	$64,483	FundraisingAmt

Payroll Taxes PayrollTaxesGrp

Field	Value	IRS element (for citing)
Total	$140,147	TotalAmt
Program Services	$87,925	ProgramServicesAmt
Management And General	$19,453	ManagementAndGeneralAmt
Fundraising	$32,769	FundraisingAmt

Fees For Services Legal FeesForServicesLegalGrp

Field	Value	IRS element (for citing)
Total	$38,838	TotalAmt
Program Services	$25,875	ProgramServicesAmt
Management And General	$10,766	ManagementAndGeneralAmt
Fundraising	$2,197	FundraisingAmt

Fees For Services Accounting FeesForServicesAccountingGrp

Field	Value	IRS element (for citing)
Total	$26,179	TotalAmt
Management And General	$26,179	ManagementAndGeneralAmt

Fees For Services Lobbying FeesForServicesLobbyingGrp

Field	Value	IRS element (for citing)
Total	$112,980	TotalAmt
Program Services	$112,980	ProgramServicesAmt

Fees For Services Other FeesForServicesOtherGrp

Field	Value	IRS element (for citing)
Total	$369,033	TotalAmt
Program Services	$228,093	ProgramServicesAmt
Management And General	$16,900	ManagementAndGeneralAmt
Fundraising	$124,040	FundraisingAmt

Advertising AdvertisingGrp

Field	Value	IRS element (for citing)
Total	$24,836	TotalAmt
Program Services	$24,608	ProgramServicesAmt
Fundraising	$228	FundraisingAmt

Office Expenses OfficeExpensesGrp

Field	Value	IRS element (for citing)
Total	$256,679	TotalAmt
Program Services	$140,716	ProgramServicesAmt
Management And General	$8,501	ManagementAndGeneralAmt
Fundraising	$107,462	FundraisingAmt

Information Technology InformationTechnologyGrp

Field	Value	IRS element (for citing)
Total	$172,599	TotalAmt
Program Services	$90,501	ProgramServicesAmt
Management And General	$20,808	ManagementAndGeneralAmt
Fundraising	$61,290	FundraisingAmt

Occupancy OccupancyGrp

Field	Value	IRS element (for citing)
Total	$128,139	TotalAmt
Program Services	$80,284	ProgramServicesAmt
Management And General	$17,669	ManagementAndGeneralAmt
Fundraising	$30,186	FundraisingAmt

Travel TravelGrp

Field	Value	IRS element (for citing)
Total	$13,890	TotalAmt
Program Services	$8,415	ProgramServicesAmt
Management And General	$1,692	ManagementAndGeneralAmt
Fundraising	$3,783	FundraisingAmt

Conferences Meetings ConferencesMeetingsGrp

Field	Value	IRS element (for citing)
Total	$76,847	TotalAmt
Program Services	$76,630	ProgramServicesAmt
Management And General	$55	ManagementAndGeneralAmt
Fundraising	$162	FundraisingAmt

Depreciation Depletion DepreciationDepletionGrp

Field	Value	IRS element (for citing)
Total	$73,200	TotalAmt
Program Services	$50,381	ProgramServicesAmt
Management And General	$6,465	ManagementAndGeneralAmt
Fundraising	$16,354	FundraisingAmt

Insurance InsuranceGrp

Field	Value	IRS element (for citing)
Total	$11,222	TotalAmt
Program Services	$7,040	ProgramServicesAmt
Management And General	$1,558	ManagementAndGeneralAmt
Fundraising	$2,624	FundraisingAmt

Other Expenses OtherExpensesGrp (4 entries)

DescDesc	TotalTotalAmt	Program ServicesProgramServicesAmt	Management And GeneralManagementAndGeneralAmt	FundraisingFundraisingAmt
PRECLINICAL CONSORTIUM	$1,824,180	$1,824,180
NHD BIOSAMPLE REPOSIT	$266,285	$266,285
DUES AND SUBSCRIPTIONS	$48,878	$29,979	$12,767	$6,132
MISCELLANEOUS EXPENSES	$8,527	$3,443	$3,848	$1,236

All Other Expenses AllOtherExpensesGrp

Field	Value	IRS element (for citing)
Total	$13,074	TotalAmt
Program Services	$5,280	ProgramServicesAmt
Management And General	$5,898	ManagementAndGeneralAmt
Fundraising	$1,896	FundraisingAmt

Total Functional Expenses TotalFunctionalExpensesGrp

Field	Value	IRS element (for citing)
Total	$6,869,562	TotalAmt
Program Services	$5,465,347	ProgramServicesAmt
Management And General	$517,692	ManagementAndGeneralAmt
Fundraising	$886,523	FundraisingAmt

Field	Value	IRS element (for citing)
Joint Costs	Yes (X)	JointCostsInd

Total Joint Costs TotalJointCostsGrp

Field	Value	IRS element (for citing)
Total	$33,150	TotalAmt
Program Services	$16,575	ProgramServicesAmt
Management And General	$0	ManagementAndGeneralAmt
Fundraising	$16,575	FundraisingAmt

Cash Non Interest Bearing CashNonInterestBearingGrp

Field	Value	IRS element (for citing)
BOY	$1,097,500	BOYAmt
EOY	$1,459,324	EOYAmt

Savings And Temp Cash Invst SavingsAndTempCashInvstGrp

Field	Value	IRS element (for citing)
BOY	$1,238,876	BOYAmt
EOY	$1,242,438	EOYAmt

Pledges And Grants Receivable PledgesAndGrantsReceivableGrp

Field	Value	IRS element (for citing)
BOY	$1,578,285	BOYAmt
EOY	$2,698,495	EOYAmt

Accounts Receivable AccountsReceivableGrp

Field	Value	IRS element (for citing)
BOY	$113,491	BOYAmt
EOY	$99,173	EOYAmt

Prepaid Expenses Defrd Charges PrepaidExpensesDefrdChargesGrp

Field	Value	IRS element (for citing)
BOY	$392,003	BOYAmt
EOY	$620,148	EOYAmt

Field	Value	IRS element (for citing)
Land Bldg Equip Cost Or Other Bss	$719,159	LandBldgEquipCostOrOtherBssAmt
Land Bldg Equip Accum Deprec	$281,990	LandBldgEquipAccumDeprecAmt

Land Bldg Equip Basis Net LandBldgEquipBasisNetGrp

Field	Value	IRS element (for citing)
BOY	$510,367	BOYAmt
EOY	$437,169	EOYAmt

Other Assets Total OtherAssetsTotalGrp

Field	Value	IRS element (for citing)
BOY	$6,727,351	BOYAmt
EOY	$7,490,119	EOYAmt

Total Assets TotalAssetsGrp

Field	Value	IRS element (for citing)
BOY	$11,657,873	BOYAmt
EOY	$14,046,866	EOYAmt

Accounts Payable Accr Expnss AccountsPayableAccrExpnssGrp

Field	Value	IRS element (for citing)
BOY	$435,478	BOYAmt
EOY	$472,049	EOYAmt

Deferred Revenue DeferredRevenueGrp

Field	Value	IRS element (for citing)
BOY	$422,226	BOYAmt
EOY	$676,798	EOYAmt

Other Liabilities OtherLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$1,337,608	BOYAmt
EOY	$1,289,033	EOYAmt

Total Liabilities TotalLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$2,195,312	BOYAmt
EOY	$2,437,880	EOYAmt

Field	Value	IRS element (for citing)
Organization Follows FASB117	Yes (X)	OrganizationFollowsFASB117Ind

No Donor Restriction Net Assets NoDonorRestrictionNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$5,954,477	BOYAmt
EOY	$6,580,605	EOYAmt

Donor Restriction Net Assets DonorRestrictionNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$3,508,084	BOYAmt
EOY	$5,028,381	EOYAmt

Total Net Assets Fund Balance TotalNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$9,462,561	BOYAmt
EOY	$11,608,986	EOYAmt

Tot Liab Net Assets Fund Balance TotLiabNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$11,657,873	BOYAmt
EOY	$14,046,866	EOYAmt

Field	Value	IRS element (for citing)
Reconcilation Revenue Expnss	$2,146,425	ReconcilationRevenueExpnssAmt
Other Changes In Net Assets	$0	OtherChangesInNetAssetsAmt
Method Of Accounting Accrual	Yes (X)	MethodOfAccountingAccrualInd
Accountant Compile Or Review	0	AccountantCompileOrReviewInd
FS Audited	Yes (1)	FSAuditedInd

FS Audited Basis FSAuditedBasisGrp

Field	Value	IRS element (for citing)
Consolidated Basis Fincl Stmt	Yes (X)	ConsolidatedBasisFinclStmtInd

Field	Value	IRS element (for citing)
Audit Committee	Yes (1)	AuditCommitteeInd
Federal Grant Audit Required	0	FederalGrantAuditRequiredInd

Schedule A IRS990ScheduleA

Field	Value	IRS element (for citing)
Public Organization170	Yes (X)	PublicOrganization170Ind

Gifts Grants Contri Rcvd170 GiftsGrantsContriRcvd170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$3,949,953	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$4,105,376	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$5,527,543	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$4,345,011	CurrentTaxYearMinus1YearAmt
Current Tax Year	$5,769,053	CurrentTaxYearAmt
Total	$23,696,936	TotalAmt

Total Calendar Year170 TotalCalendarYear170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$3,949,953	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$4,105,376	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$5,527,543	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$4,345,011	CurrentTaxYearMinus1YearAmt
Current Tax Year	$5,769,053	CurrentTaxYearAmt
Total	$23,696,936	TotalAmt

Field	Value	IRS element (for citing)
Substantial Contributors Tot	$3,559,289	SubstantialContributorsTotAmt
Public Support Total170	$20,137,647	PublicSupportTotal170Amt

Gross Investment Income170 GrossInvestmentIncome170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$10,393	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$13,784	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$27,444	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$11,188	CurrentTaxYearMinus1YearAmt
Current Tax Year	$3,809	CurrentTaxYearAmt
Total	$66,618	TotalAmt

Other Income170 OtherIncome170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$642	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$1,243	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$714	CurrentTaxYearMinus2YearsAmt
Total	$2,599	TotalAmt

Field	Value	IRS element (for citing)
Total Support	$23,766,153	TotalSupportAmt
Gross Receipts Rltd Activities	$10,327,170	GrossReceiptsRltdActivitiesAmt
Public Support CY170	0.84730	PublicSupportCY170Pct
Public Support PY170	0.84300	PublicSupportPY170Pct
Thirty Thr Pct Suprt Tests CY170	Yes (X)	ThirtyThrPctSuprtTestsCY170Ind

Form990 Schedule A Part VI Form990ScheduleAPartVIGrp

Field	Value	IRS element (for citing)
Form And Line Reference	SCHEDULE A, PART II, LINE 10, EXPLANATION OF OTHER INCOME:	FormAndLineReferenceDesc
Explanation	INCOME FROM ACTIVITIES NOT REGULARLY CARRIED ON - 2017 AMOUNT: $ 642. 2018 AMOUNT: $ 1,243. 2019 AMOUNT: $ 714.	ExplanationTxt

Schedule B IRS990ScheduleB

Contributor Information ContributorInformationGrp

Field	Value	IRS element (for citing)
Contributor	RESTRICTED	ContributorNum

Contributor Business Name ContributorBusinessName

Field	Value	IRS element (for citing)
Business Name Line1	RESTRICTED	BusinessNameLine1

Contributor US Address ContributorUSAddress

Field	Value	IRS element (for citing)
Address Line1	RESTRICTED	AddressLine1
Address Line2	RESTRICTED	AddressLine2
City	RESTRICTED	City
State	RESTRICTED	State
ZIP Code	RESTRICTED	ZIPCode

Field	Value	IRS element (for citing)
Total Contributions	RESTRICTED	TotalContributionsAmt

Schedule C IRS990ScheduleC

Total Grassroots Lobbying TotalGrassrootsLobbyingGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$1,127	FilingOrganizationsTotalAmt

Total Direct Lobbying TotalDirectLobbyingGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$153,012	FilingOrganizationsTotalAmt

Total Lobbying Expend TotalLobbyingExpendGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$154,139	FilingOrganizationsTotalAmt

Other Exempt Purpose Expend OtherExemptPurposeExpendGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$6,795,167	FilingOrganizationsTotalAmt

Total Exempt Purpose Expend TotalExemptPurposeExpendGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$6,949,306	FilingOrganizationsTotalAmt

Lobbying Nontaxable Amount LobbyingNontaxableAmountGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$497,465	FilingOrganizationsTotalAmt

Grassroots Nontaxable GrassrootsNontaxableGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$124,366	FilingOrganizationsTotalAmt

Tot Lbbyng Grassroot Mns Non Tx TotLbbyngGrassrootMnsNonTxGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$0	FilingOrganizationsTotalAmt

Tot Lbby Expend Mns Lbbyng Non Tx TotLbbyExpendMnsLbbyngNonTxGrp

Field	Value	IRS element (for citing)
Filing Organizations Total	$0	FilingOrganizationsTotalAmt

Avg Lobbying Nontaxable Amount AvgLobbyingNontaxableAmountGrp

Field	Value	IRS element (for citing)
Current Year Minus3	$450,555	CurrentYearMinus3Amt
Current Year Minus2	$445,393	CurrentYearMinus2Amt
Current Year Minus1	$423,685	CurrentYearMinus1Amt
Current Year	$497,465	CurrentYearAmt
Total	$1,817,098	TotalAmt

Field	Value	IRS element (for citing)
Lobbying Ceiling	$2,725,647	LobbyingCeilingAmt

Avg Total Lobbying Expend AvgTotalLobbyingExpendGrp

Field	Value	IRS element (for citing)
Current Year Minus3	$149,340	CurrentYearMinus3Amt
Current Year Minus2	$165,226	CurrentYearMinus2Amt
Current Year Minus1	$123,014	CurrentYearMinus1Amt
Current Year	$154,139	CurrentYearAmt
Total	$591,719	TotalAmt

Avg Grassroots Nontaxable AvgGrassrootsNontaxableGrp

Field	Value	IRS element (for citing)
Current Year Minus3	$112,639	CurrentYearMinus3Amt
Current Year Minus2	$111,348	CurrentYearMinus2Amt
Current Year Minus1	$105,921	CurrentYearMinus1Amt
Current Year	$124,366	CurrentYearAmt
Total	$454,274	TotalAmt

Field	Value	IRS element (for citing)
Grassroots Ceiling	$681,411	GrassrootsCeilingAmt

Avg Grassroots Lobbying Expend AvgGrassrootsLobbyingExpendGrp

Field	Value	IRS element (for citing)
Current Year Minus3	$823	CurrentYearMinus3Amt
Current Year Minus2	$2,491	CurrentYearMinus2Amt
Current Year Minus1	$895	CurrentYearMinus1Amt
Current Year	$1,127	CurrentYearAmt
Total	$5,336	TotalAmt

Schedule D IRS990ScheduleD

CY Endwmt Fund CYEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$5,893,521	BeginningYearBalanceAmt
Contributions	$132,476	ContributionsAmt
Investment Earnings Or Losses	$1,053,588	InvestmentEarningsOrLossesAmt
Other Expenditures	$333,813	OtherExpendituresAmt
Administrative Expenses	$34,024	AdministrativeExpensesAmt
End Year Balance	$6,711,748	EndYearBalanceAmt

CY Minus1 Yr Endwmt Fund CYMinus1YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$5,915,805	BeginningYearBalanceAmt
Contributions	$54,645	ContributionsAmt
Investment Earnings Or Losses	$416,431	InvestmentEarningsOrLossesAmt
Other Expenditures	$463,721	OtherExpendituresAmt
Administrative Expenses	$29,639	AdministrativeExpensesAmt
End Year Balance	$5,893,521	EndYearBalanceAmt

CY Minus2 Yr Endwmt Fund CYMinus2YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$5,193,934	BeginningYearBalanceAmt
Contributions	$78,962	ContributionsAmt
Investment Earnings Or Losses	$959,121	InvestmentEarningsOrLossesAmt
Other Expenditures	$288,356	OtherExpendituresAmt
Administrative Expenses	$27,856	AdministrativeExpensesAmt
End Year Balance	$5,915,805	EndYearBalanceAmt

CY Minus3 Yr Endwmt Fund CYMinus3YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$5,655,555	BeginningYearBalanceAmt
Contributions	$82,346	ContributionsAmt
Investment Earnings Or Losses	-$439,321	InvestmentEarningsOrLossesAmt
Other Expenditures	$50,000	OtherExpendituresAmt
Administrative Expenses	$54,646	AdministrativeExpensesAmt
End Year Balance	$5,193,934	EndYearBalanceAmt

CY Minus4 Yr Endwmt Fund CYMinus4YrEndwmtFundGrp

Field	Value	IRS element (for citing)
Beginning Year Balance	$5,293,989	BeginningYearBalanceAmt
Contributions	$92,635	ContributionsAmt
Investment Earnings Or Losses	$739,072	InvestmentEarningsOrLossesAmt
Other Expenditures	$403,000	OtherExpendituresAmt
Administrative Expenses	$67,141	AdministrativeExpensesAmt
End Year Balance	$5,655,555	EndYearBalanceAmt

Field	Value	IRS element (for citing)
Board Designated Balance EOY	0.84560	BoardDesignatedBalanceEOYPct
Prmnnt Endowment Balance EOY	0.13100	PrmnntEndowmentBalanceEOYPct
Term Endowment Balance EOY	0.02340	TermEndowmentBalanceEOYPct
Endowments Held Unrelated Org	0	EndowmentsHeldUnrelatedOrgInd
Endowments Held Related Org	Yes (1)	EndowmentsHeldRelatedOrgInd
Related Org List Sch R	Yes (1)	RelatedOrgListSchRInd

Leasehold Improvements LeaseholdImprovementsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$449,272	OtherCostOrOtherBasisAmt
Depreciation	$71,475	DepreciationAmt
Book Value	$377,797	BookValueAmt

Equipment EquipmentGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$189,615	OtherCostOrOtherBasisAmt
Depreciation	$134,797	DepreciationAmt
Book Value	$54,818	BookValueAmt

Other Land Buildings OtherLandBuildingsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$80,272	OtherCostOrOtherBasisAmt
Depreciation	$75,718	DepreciationAmt
Book Value	$4,554	BookValueAmt

Field	Value	IRS element (for citing)
Total Book Value Land Buildings	$437,169	TotalBookValueLandBuildingsAmt

Other Assets Org OtherAssetsOrgGrp (2 entries)

DescDesc	Book ValueBookValueAmt
INTEREST IN NET ASSETS OF AFFILIATE	$6,711,748
OPERATING LEASE RIGHT-OF-USE ASSET	$778,371

Field	Value	IRS element (for citing)
Total Book Value Other Assets	$7,490,119	TotalBookValueOtherAssetsAmt

Other Liabilities Org OtherLiabilitiesOrgGrp (2 entries)

DescDesc	AmtAmt
DEFERRED RENT & LEASE INCENTIVE	$1,285,691
DUE TO AFFILIATE	$3,342

Field	Value	IRS element (for citing)
Total Liability	$1,289,033	TotalLiabilityAmt
Total Rev Etc Audited Fincl Stmt	$9,050,015	TotalRevEtcAuditedFinclStmtAmt
Donated Services And Use Fclts	$34,028	DonatedServicesAndUseFcltsAmt
Revenue Not Reported	$34,028	RevenueNotReportedAmt
Revenue Subtotal	$9,015,987	RevenueSubtotalAmt
Revenue Not Reported Fincl Stmt	$0	RevenueNotReportedFinclStmtAmt
Total Revenue Per Form990	$9,015,987	TotalRevenuePerForm990Amt
Tot Expns Etc Audited Fincl Stmt	$6,903,590	TotExpnsEtcAuditedFinclStmtAmt
Donated Services Use Fclts	$34,028	DonatedServicesUseFcltsAmt
Expenses Not Reported	$34,028	ExpensesNotReportedAmt
Expenses Subtotal	$6,869,562	ExpensesSubtotalAmt
Expenses Not Rpt Fincl Stmt	$0	ExpensesNotRptFinclStmtAmt
Total Expenses Per Form990	$6,869,562	TotalExpensesPerForm990Amt

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	PART V, LINE 4:	FormAndLineReferenceDesc
Explanation	THE ALLIANCE'S ENDOWMENTS CONSIST OF TWO FUNDS ESTABLISHED FOR DIFFERENT PURPOSES. THE ALLIANCE'S ENDOWMENT INCLUDE ONE TRADITIONAL DONOR-RESTRICTED ENDOWMENT FUNDS AND ONE BOARD-DESIGNATED ENDOWMENT FUND. THE BOARD-DESIGNATED ENDOWMENT FUND SOLELY CONSISTS OF THE ENDOWMENT FUND'S UNRESTRICTED NET ASSET BALANCE.	ExplanationTxt

Schedule F IRS990ScheduleF

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (1)	GrantRecordsMaintainedInd

Account Activities Outside US AccountActivitiesOutsideUSGrp (4 entries)

RegionRegionTxt	Type Of Activities ConductedTypeOfActivitiesConductedTxt	Region Total ExpendituresRegionTotalExpendituresAmt	Specific Services ProvidedSpecificServicesProvidedTxt
EUROPE (INCLUDING ICELAND & GREENLAND)	GRANTMAKING	$19,907
MIDDLE EAST AND NORTH AFRICA	GRANTMAKING	$75,000
EUROPE (INCLUDING ICELAND & GREENLAND)	PROGRAM SERVICE ACTIVITIES	$4,177	PRECLINICAL RESEARCH STUDIES
NORTH AMERICA	GRANTMAKING	$20,000

Field	Value	IRS element (for citing)
Subtotal Offices	0	SubtotalOfficesCnt
Subtotal Employees	0	SubtotalEmployeesCnt
Continuation Total Office	0	ContinuationTotalOfficeCnt
Continuation Total Employee	0	ContinuationTotalEmployeeCnt
Total Office	0	TotalOfficeCnt
Total Employee	0	TotalEmployeeCnt
Subtotal Spent	$119,084	SubtotalSpentAmt
Continuation Spent	$0	ContinuationSpentAmt
Total Spent	$119,084	TotalSpentAmt

Grants To Org Outside US GrantsToOrgOutsideUSGrp (3 entries)

RegionRegionTxt	Purpose Of GrantPurposeOfGrantTxt	Cash GrantCashGrantAmt	Manner Of Cash DisbursementMannerOfCashDisbursementTxt	Non Cash AssistanceNonCashAssistanceAmt
MIDDLE EAST AND NORTH AFRICA	RESEARCH ON TUBEROUS SCLEROSIS COMPLEX	$75,000	WIRE	$0
EUROPE (INCLUDING ICELAND & GREENLAND)	PROGRAMMATIC SUPPORT	$19,907	WIRE	$0
NORTH AMERICA	GRANTMAKING	$20,000	CHECK	$0

Field	Value	IRS element (for citing)
Total501c3 Org	0	Total501c3OrgCnt
Total Other Org	3	TotalOtherOrgCnt
Transfer To Foreign Corp	0	TransferToForeignCorpInd
Interest In Foreign Trust	0	InterestInForeignTrustInd
Foreign Corp Ownership	0	ForeignCorpOwnershipInd
Passive Foreign Investmest Co	0	PassiveForeignInvestmestCoInd
Foreign Partnership	0	ForeignPartnershipInd
Boycott Countries	0	BoycottCountriesInd

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
PART I, LINE 2:	GRANTEE ORGANIZATIONS ARE EXPECTED TO FILE ANNUAL PROGRESS REPORTS TO OUTLINED GRANT GOALS AND MILESTONES. THESE REPORTS ARE REVIEWED BY A COMMITTEE OF PEERS. THIS COMMITTEE MAKES DETERMINATIONS BASED ON QUALITY OF WORK TO GOALS AND IF THE GRANTEE WILL CONTINUE TO RECEIVE FUNDING. A FINAL WRITTEN AND FINANCIAL REPORT IS REQUIRED OF ALL GRANTEES.
PART III ACCOUNTING METHOD:

Schedule G IRS990ScheduleG

Fundraising Event Information FundraisingEventInformationGrp

Field	Value	IRS element (for citing)
Event1	VIRTUAL WALKS	Event1Nm
Gross Receipts Event1	$806,174	GrossReceiptsEvent1Amt
Charitable Contri Event1	$650,809	CharitableContriEvent1Amt
Gross Revenue Event1	$155,365	GrossRevenueEvent1Amt
Non Cash Prizes Event1	$20,365	NonCashPrizesEvent1Amt
Rent Facility Costs Event1	$154	RentFacilityCostsEvent1Amt
Event2	COMEDY FOR A CURE	Event2Nm
Gross Receipts Event2	$142,870	GrossReceiptsEvent2Amt
Charitable Contri Event2	$100,282	CharitableContriEvent2Amt
Gross Revenue Event2	$42,588	GrossRevenueEvent2Amt
Non Cash Prizes Event2	$1,093	NonCashPrizesEvent2Amt
Rent Facility Costs Event2	$15,891	RentFacilityCostsEvent2Amt
Entertainment Event2	$1,400	EntertainmentEvent2Amt
Other Events Total	7	OtherEventsTotalCnt
Gross Receipts Other Events	$240,768	GrossReceiptsOtherEventsAmt
Charitable Contri Other Events	$204,239	CharitableContriOtherEventsAmt
Gross Revenue Other Events	$36,529	GrossRevenueOtherEventsAmt
Non Cash Prizes Other Events	$2,313	NonCashPrizesOtherEventsAmt
Rent Fclty Costs Other Events	$4,500	RentFcltyCostsOtherEventsAmt
Gross Receipts Total	$1,189,812	GrossReceiptsTotalAmt
Charitable Contributions Tot	$955,330	CharitableContributionsTotAmt
Gross Revenue Total Events	$234,482	GrossRevenueTotalEventsAmt
Non Cash Prizes Total Events	$23,771	NonCashPrizesTotalEventsAmt
Rent Fclty Costs Total Events	$20,545	RentFcltyCostsTotalEventsAmt
Entertainment Total Events	$1,400	EntertainmentTotalEventsAmt
Direct Expense Summary Events	$45,716	DirectExpenseSummaryEventsAmt
Net Income Summary	$188,766	NetIncomeSummaryAmt

Schedule I IRS990ScheduleI

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (1)	GrantRecordsMaintainedInd

Recipient Table RecipientTable (12 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	Recipient EINRecipientEIN	IRC SectionIRCSectionDesc	Cash GrantCashGrantAmt	Non Cash AssistanceNonCashAssistanceAmt	Purpose Of GrantPurposeOfGrantTxt
BRIGHAM & WOMEN'S HOSPITAL
75 FRANCIS STREET	BOSTON	MA	02115	042312909	501(C)(3)	$109,963	$0	RESEARCH GRANTS
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER
5323 HARRY HINES BLVD	DALLAS	TX	75287	756002868	501(C)(3)	$18,750	$0	RESEARCH GRANTS
NATIONAL ORGANIZATION FOR RARE DISORDERS
55 KENOSIA AVENUE	DANBURY	CT	06810	133223946	501(C)(3)	$225,000	$0	TSC TRAVEL AND LODGING ASSISTANCE PROGRAM
NORTHWESTERN UNIVERSITY
7TH FLOOR RUBLOFF BUILDING	CHICAGO	IL	60611	362167818	501(C)(3)	$56,250	$0	RESEARCH GRANTS
CHILDREN'S HOSPITAL CORPORATION
300 LONGWOOD AVENUE	BOSTON	MA	02115	042774441	501(C)(3)	$112,500	$0	RESEARCH GRANTS
UNIVERSITY OF CALIFORNIA BERKELEY
1608 FOURTH ST STE 220	BERKELEY	CA	94710	946002123	501(C)(3)	$28,125	$0	RESEARCH GRANT
VANDERBILT UNIVERSITY
1161 21ST AVE SOUTH	NASHVILLE	TN	37232	352528741	501(C)(3)	$28,125	$0	RESEARCH GRANT
UNIVERSITY OF MARYLAND BALTIMORE
PO BOX 41428	BALTIMORE	MD	21203	526002033	501(C)(3)	$18,634	$0	RESEARCH GRANT
UNIVERSITY OF WASHINGTON
4333 BROOKLYN AVE NE BOX 359472	SEATTLE	WA	98195	916001537	501(C)(3)	$25,000	$0	RESEARCH GRANT
CHILDREN'S HOSPITAL MEDICAL CENTER
3333 BURNET AVENUE	CINCINNATI	OH	45229	310833936	501(C)(3)	$100,000	$0	CLINICAL RESEARCH
BROWN UNIVERSITY
69 BROWN STREET BOX 1911	PROVIDENCE	RI	02912	050258809	501(C)(3)	$55,000	$0	CLINICAL RESEARCH
BOSTON CHILDREN'S HOSPITAL
PO BOX 414413	BOSTON	MA	022414413	042774441	501(C)(3)	$57,409	$0	CLINICAL RESEARCH

Field	Value	IRS element (for citing)
Total501c3 Org	12	Total501c3OrgCnt
Total Other Org	0	TotalOtherOrgCnt

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	PART I, LINE 2:	FormAndLineReferenceDesc
Explanation	THE TSC ALLIANCE HAS FUNDED $31 MILLION IN RESEARCH ON TSC SINCE 1984. DIRECTED BY STEVEN L. ROBERDS, PH.D, CHIEF SCIENTIFIC OFFICER, THE TSC ALLIANCE RESEARCH GRANTS PROGRAM FUNDS RESEARCH FOCUSED ON TSC WITH PRIORITIES SET BY THE RESEARCHERS TOGETHER WITH THE TSC ALLIANCE. COLLABORATIONS BETWEEN BASIC AND CLINICAL RESEARCHERS ARE ENCOURAGED AND FOSTERED, AND THE TSC ALLIANCE IS WORKING TO INCREASE FUNDING FOR RESEARCH ON TSC. THROUGH THE TSC ALLIANCE RESEARCH GRANTS PROGRAM, APPLICATIONS CAN BE SUBMITTED FOR POSTDOCTORAL FELLOWSHIPS AND TSC RESEARCH GRANTS. GRANTS ARE REVIEWED IN A THREE-STEP PROCESS: 1. A GRANT REVIEW COMMITTEE COMPOSED OF INDIVIDUALS KNOWLEDGEABLE ABOUT THE CLINICAL AND BASIC COMPONENTS OF TSC AS WELL AS CONSUMERS REVIEW ALL GRANT APPLICATIONS FOR SCIENTIFIC MERIT, RELEVANCY TO THE FUNDING PRIORITIES OF THE ORGANIZATION AND WITH A FOCUS ON UNDERSTANDING THE MECHANISMS OF TSC AND/OR THE DEVELOPMENT OF TREATMENTS AND THERAPIES FOR THE MANIFESTATIONS OF THE DISEASE. 2. THE SCIENCE AND MEDICAL COMMITTEE OF THE BOARD OF DIRECTORS THEN REVIEWS THE GRANT REVIEW COMMITTEE'S CONCLUSIONS AND MAKES FUNDING RECOMMENDATIONS TO THE BOARD OF DIRECTORS. 3. THE BOARD OF DIRECTORS THEN REVIEWS THE RECOMMENDATIONS OF THE SCIENCE AND MEDICAL COMMITTEE AND MAKES FINAL APPROVAL FOR THE FUNDING OF GRANTS.	ExplanationTxt

Schedule J IRS990ScheduleJ

Field	Value	IRS element (for citing)
Compensation Committee	Yes (X)	CompensationCommitteeInd
Form990 Of Other Organizations	Yes (X)	Form990OfOtherOrganizationsInd
Compensation Survey	Yes (X)	CompensationSurveyInd
Board Or Committee Approval	Yes (X)	BoardOrCommitteeApprovalInd
Severance Payment	0	SeverancePaymentInd
Supplemental Nonqual Rtr Plan	0	SupplementalNonqualRtrPlanInd
Equity Based Comp Arrngm	0	EquityBasedCompArrngmInd
Comp Based On Revenue Of Flng Org	Yes (1)	CompBasedOnRevenueOfFlngOrgInd
Comp Bsd On Rev Related Orgs	0	CompBsdOnRevRelatedOrgsInd
Comp Bsd Net Earns Flng Org	Yes (1)	CompBsdNetEarnsFlngOrgInd
Comp Bsd Net Earns Rltd Orgs	0	CompBsdNetEarnsRltdOrgsInd
Any Non Fixed Payments	0	AnyNonFixedPaymentsInd
Initial Contract Exception	0	InitialContractExceptionInd

Rltd Org Officer Trst Key Empl RltdOrgOfficerTrstKeyEmplGrp (4 entries)

TitleTitleTxt	Base Compensation Filing OrgBaseCompensationFilingOrgAmt	Compensation Based On Rltd OrgsCompensationBasedOnRltdOrgsAmt	Bonus Filing OrganizationBonusFilingOrganizationAmount	Bonus Related OrganizationsBonusRelatedOrganizationsAmt	Other Compensation Filing OrgOtherCompensationFilingOrgAmt	Other Compensation Rltd OrgsOtherCompensationRltdOrgsAmt	Deferred Compensation Flng OrgDeferredCompensationFlngOrgAmt	Deferred Comp Rltd OrgsDeferredCompRltdOrgsAmt	Nontaxable Benefits Filing OrgNontaxableBenefitsFilingOrgAmt	Nontaxable Benefits Rltd OrgsNontaxableBenefitsRltdOrgsAmt	Total Compensation Filing OrgTotalCompensationFilingOrgAmt	Total Compensation Rltd OrgsTotalCompensationRltdOrgsAmt	Comp Report Prior990 Filing OrgCompReportPrior990FilingOrgAmt	Comp Report Prior990 Rltd OrgsCompReportPrior990RltdOrgsAmt
STEVEN L ROBERDS
CHIEF SCIENTIFIC OFFICER	$212,421	$0	$16,175	$0	$258	$0	$7,007	$0	$24,311	$0	$260,172	$0	$0	$0
KARI L ROSBECK
PRESIDENT & CEO	$196,498	$3,638	$17,866	$331	$244	$5	$6,806	$0	$30,738	$0	$252,152	$3,974	$0	$0
RICHARD GOLLUB
CFO	$146,390	$9,344	$9,972	$636	$372	$24	$5,207	$0	$32,130	$0	$194,071	$10,004	$0	$0
DEAN RAGER-AGUIAR
DIRECTOR, PRECLINICAL RESEARCH	$157,178	$0	$6,379	$0	$138	$0	$5,180	$0	$31,130	$0	$200,005	$0	$0	$0

Supplemental Information Detail SupplementalInformationDetail (2 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
PART I, LINE 5	KARI LUTHER ROSBECK, RICHARD GOLLUB, STEVE ROBERDS, DEAN AGUIAR, JAYE ISHAM, LISA MOSS AND APRIL COOPER ALL HAVE INCENTIVE COMPENSATION EQUAL TO A PERCENTAGE OF THEIR SALARIES BASED ON KEY PERFORMANCE OBJECTIVES AS ESTABLISHED BY THE COMPENSATION COMMITTEE.
PART I, LINE 6	KARI LUTHER ROSBECK, RICHARD GOLLUB, STEVE ROBERDS, DEAN AGUIAR, JAYE ISHAM, LISA MOSS AND APRIL COOPER ALL HAVE INCENTIVE COMPENSATION EQUAL TO A PERCENTAGE OF THEIR SALARIES BASED ON KEY PERFORMANCE OBJECTIVES AS ESTABLISHED BY THE COMPENSATION COMMITTEE.

Schedule M IRS990ScheduleM

Books And Publications BooksAndPublicationsGrp

Field	Value	IRS element (for citing)
Non Cash Checkbox	Yes (X)	NonCashCheckboxInd
Noncash Contributions Rpt F990	$34,028	NoncashContributionsRptF990Amt
Method Of Determining Revenues	FMV	MethodOfDeterminingRevenuesTxt

Clothing And Household Goods ClothingAndHouseholdGoodsGrp

Field	Value	IRS element (for citing)
Non Cash Checkbox	Yes (X)	NonCashCheckboxInd
Noncash Contributions Rpt F990	$724	NoncashContributionsRptF990Amt
Method Of Determining Revenues	FMV	MethodOfDeterminingRevenuesTxt

Securities Publicly Traded SecuritiesPubliclyTradedGrp

Field	Value	IRS element (for citing)
Non Cash Checkbox	Yes (X)	NonCashCheckboxInd
Contribution	7	ContributionCnt
Noncash Contributions Rpt F990	$250,515	NoncashContributionsRptF990Amt
Method Of Determining Revenues	FMV	MethodOfDeterminingRevenuesTxt

Field	Value	IRS element (for citing)
Form8283 Received	0	Form8283ReceivedCnt
Any Property That Must Be Held	0	AnyPropertyThatMustBeHeldInd
Review Process Unusual NC Gifts	Yes (1)	ReviewProcessUnusualNCGiftsInd
Third Parties Used	0	ThirdPartiesUsedInd

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	PART I, COLUMN (B):	FormAndLineReferenceDesc
Explanation	REPORTING THE NUMBER OF CONTRIBUTIONS	ExplanationTxt

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (8 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
FORM 990, PART III, LINE 4A	THE PRECLINICAL CONSORTIUM INVITES COMPOUND NOMINATIONS FROM ACADEMIC AND INDUSTRY RESEARCHERS TO CONTINUE TO REFRESH OUR PIPELINE BASED ON THE LATEST DATA AND NOVEL IDEAS. THE NOMINATIONS ARE PEER-REVIEWED BY CONSORTIUM MEMBERS AND PRIORITIZED BY THE PRECLINICAL CONSORTIUM STEERING COMMITTEE FOR FUNDING BY THE TSC ALLIANCE. IF THE TSC ALLIANCE FUNDS THE STUDY, THE DATA ARE SHARED WITH THE CONSORTIUM FOR TRANSPARENCY AND STIMULATION OF ADDITIONAL HYPOTHESES. AN ANNUAL FACE-TO-FACE MEMBERS MEETING IS TYPICALLY HELD EACH YEAR IN APRIL TO KEEP MEMBERS ENGAGED AND ALIGNED ON THE CONSORTIUM'S STRATEGY AND PRIORITIES. PARTNERSHIP WITH PHARMACEUTICAL COMPANIES IS AN IMPORTANT ASPECT OF THE CONSORTIUM, AS THESE ORGANIZATIONS HAVE THE INFRASTRUCTURE TO EFFICIENTLY MOVE PRECLINICAL RESEARCH FINDINGS TO CLINICAL TESTING AND EVENTUALLY COMMERCIAL DISTRIBUTION. AS OF DECEMBER 2021, 10 COMPANIES WERE ACTIVE MEMBERS OF THE CONSORTIUM. THE CONSORTIUM HAS HAD 17 COMPANY MEMBERS SINCE 2016. THERE IS NATURAL TURNOVER OF INDUSTRY MEMBERSHIP, PRINCIPALLY DRIVEN BY RESEARCH DATA GENERATED BY TESTING THEIR DRUGS. DUE TO INTELLECTUAL PROPERTY CONSIDERATIONS, MOST COMPANIES FULLY FUND THEIR STUDIES THROUGH THE TSC ALLIANCE, WHICH ALLOWS THE COMPANY TO KEEP ITS DATA CONFIDENTIAL. THESE CONFIDENTIAL STUDIES ALSO INCUR A 10% OVERHEAD PAID BY THE COMPANY, WHICH IS A SOURCE OF REVENUE FOR THE TSC ALLIANCE. SINCE INCEPTION, THE CONSORTIUM HAS HELPED ADVANCE THE EVALUATION OF DRUGS FOR TSC BY CONDUCTING 90 STUDIES, EVALUATING 57 CANDIDATE DRUGS. IN 2020, THE TSC PRECLINICAL CONSORTIUM EVALUATED 9 CANDIDATE COMPOUNDS AND CONDUCTED 22 EXPERIMENTS. IN 2012, THE TSC ALLIANCE HELPED CREATE THE TSC CLINICAL RESEARCH CONSORTIUM IN PARTNERSHIP WITH INVESTIGATORS RUNNING CLINICAL STUDIES TO ENSURE CLINICAL RESEARCH IN TSC IS AS EFFICIENT AND EFFECTIVE AS POSSIBLE. SINCE THEN, TSC CLINICAL RESEARCH CONSORTIUM INVESTIGATORS HAVE BEEN AWARDED MORE THAN $39 MILLION BY THE NATIONAL INSTITUTES OF HEALTH (NIH) AND FOOD AND DRUG ADMINISTRATION (FDA) THROUGH COMPETITIVE GRANT PROCESSES. TSC ALLIANCE PERSONNEL SERVE ON THE LEADERSHIP TEAM FOR THE CONSORTIUM, ACTIVELY TRACK ENROLLMENT, AND RAISE COMMUNITY AWARENESS TO HELP IDENTIFY POTENTIAL PARTICIPANTS FOR CLINICAL STUDIES. TSC ALLIANCE ALSO PROVIDES SUPPLEMENTAL FINANCIAL SUPPORT TO ACCELERATE OR EXPAND NIH-FUNDED STUDIES. THE PREVENT TRIAL - PREVENTING EPILEPSY USING VIGABATRIN IN INFANTS WITH TSC - IS THE FIRST PREVENTATIVE TRIAL IN THE UNITED STATES FOR ANY FORM OF EPILEPSY AND HAS COMPLETED ENROLLMENT OF 86 PARTICIPANTS. WE EXPECT THE FIRST RESULTS IN THE FIRST QUARTER OF 2022 AND FINAL RESULTS IN EARLY 2023. THIS TRIAL BUILDS DIRECTLY UPON THE CLINICAL RESEARCH CONSORTIUM'S FIRST CLINICAL STUDY, WHICH IDENTIFIED SPECIFIC EEG CHANGES IN INFANTS WITH TSC PRIOR TO THE ONSET OF SEIZURES. IN THE PREVENT TRIAL, INFANTS WITH TSC RECEIVE REGULAR EEG MONITORING, AND THOSE WHO DEVELOP EEG ABNORMALITIES ARE PLACED ON EITHER VIGABATRIN OR PLACEBO. ANY INFANT WHO SUBSEQUENTLY DEVELOPS CLINICAL SEIZURES IS IMMEDIATELY PLACED ON STANDARD TREATMENT. THIS TRIAL WILL DETERMINE WHETHER TREATMENT WITH VIGABATRIN PRIOR TO THE ONSET OF CLINICAL SEIZURES IN TSC IS BENEFICIAL TO CHILDREN'S DEVELOPMENTAL AND NEUROLOGIC OUTCOMES. MORE DETAILS ABOUT THIS STUDY ARE ONLINE AT WWW.CLINICALTRIALS.GOV/CT2/SHOW/NCT02849457. IMMEDIATELY AFTER THE PREVENT TRIAL ENROLLMENT COMPLETED, A SIMILAR CLINICAL TRIAL BEGAN ENROLLING NEWBORNS WITH TSC BEFORE THE ONSET OF SEIZURES TO TEST THE EFFECTS OF SIROLIMUS ON PREVENTING OR DELAYING SEIZURE ONSET. THE STOPPING TSC ONSET AND PROGRESSION 2 (STOP-2) TRIAL ENROLLED FIVE INFANTS AT CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER AS AN INITIAL SAFETY STUDY. THE SECOND STAGE OF THE TRIAL IS NOW CALLED "SIROLIMUS TSC EPILEPSY PREVENTION STUDY (TSC-STEPS) AND THE TSC ALLIANCE HAS CONTRIBUTED $200,000 TO ENABLE THE TRIAL TO BE EXPANDED TO ADDITIONAL SITES ACROSS THE COUNTRY. THE TSC ALLIANCE IS ALSO PROVIDING SUPPLEMENTAL FUNDING AND COLLECTING BLOOD SAMPLES FOR THE DEVELOPMENTAL SYNAPTOPATHIES CONSORTIUM (DSC), AN NIH-FUNDED PROJECT THAT INCLUDES STUDIES OF TSC AND THE RELATED RARE DISORDERS PHELAN-MCDERMID SYNDROME AND PTEN HAMARTOMA SYNDROME. THESE THREE RARE DISEASES SEEM TO AFFECT CERTAIN SHARED PATHWAYS INFLUENCING THE DEVELOPMENT OF BRAIN CONNECTIONS, OR SYNAPSES. RESEARCHERS IN THIS STUDY ARE TRYING TO FIND EARLIER SIGNS OF AUTISM SPECTRUM DISORDER (ASD) AND INTELLECTUAL DISABILITY (ID) TO GAIN A BETTER UNDERSTANDING OF ASD/ID IN INDIVIDUALS WITH TSC AND ENABLE EFFECTIVE TREATMENTS AND INTERVENTIONS FOR ASD/ID TO BE FOUND. THE DSC WAS RENEWED IN 2019 FOR A SECOND 5-YEAR FUNDING PERIOD. THE TSC ALLIANCE FUNDS A PORTION OF CLINICAL RESEARCH COORDINATORS' SALARIES AT 5 SITES. IN 2021, THE TSC ALLIANCE AWARDED A TWO-YEAR CLINICAL RESEARCH TSC-DSC FELLOWSHIP TO FELIX CHAN, PHD, AT BROWN UNIVERSITY. IN ADDITION TO SPECIFIC COLLABORATIVE PROJECTS DETAILED ABOVE, THE TSC ALLIANCE STIMULATES COLLABORATION AND INNOVATION THROUGH CONVENING EXPERTS AND STAKEHOLDERS WITHIN AND OUTSIDE THE TSC FIELD. IN 2020, THE TSC ALLIANCE INTRODUCED THE CONCEPT OF AN AD HOC INNOVATION WORKSHOP FOCUSED ON A SPECIFIC RESEARCH GAP OR OPPORTUNITY. THE FIRST INNOVATION WORKSHOP TOPIC WAS NEWBORN SCREENING, HELD USING ZOOM AND POWERNOODLE IN LATE 2020 AND CULMINATING IN A ZOOM MEETING ON JANUARY 29, 2021. PARTICIPANTS INCLUDED 20 RESEARCHERS WITH TSC EXPERTISE; 19 RESEARCHERS WITH NEWBORN SCREENING EXPERIENCE FROM CDC, NIH, AND ACADEMIC LABORATORIES; AND FIVE REPRESENTATIVES OF NON-TSC ADVOCACY ORGANIZATIONS WITH NEWBORN SCREENING EXPERIENCE. FOLLOWING PEER-REVIEW BY EXPERTS IN TSC AND SCREENING RESEARCH, THE TSC ALLIANCE FULLY FUNDED TWO PROPOSALS TOTALING $164,856 FOR HYPOTHESIS-DRIVEN RESEARCH IN ASSAY DEVELOPMENT FOR EARLY DETECTION OF TSC. THE 2021 VIRTUAL INTERNATIONAL TSC & LAM RESEARCH CONFERENCE: DRIVING DISCOVERIES BEYOND BOUNDARIES HELD OCTOBER 28-30, 2021, WELCOMED 179 PEOPLE FROM 18 COUNTRIES. CO-SPONSORED BY THE TSC ALLIANCE AND THE LAM FOUNDATION, THE CONFERENCE FEATURED THREE PLENARY SESSIONS WITH 17 ORAL PRESENTATIONS AND TWO POSTER SESSIONS WITH 14 POSTERS. ADDITIONALLY, TWO HALF-DAY SESSIONS OF "TOPIC-BASED DISCUSSION" BROUGHT TOGETHER CLINICAL AND BASIC SCIENCE RESEARCHERS TO DISCUSS CROSS-CUTTING TOPICS, INCLUDING BIG DATA AND CLINICAL TRANSLATION.
FORM 990, PART VI	THE FORM 990 IS REVIEWED, IN DETAIL, BY THE BOARD OF DIRECTORS' AUDIT COMMITTEE. RECOMMENDATIONS ARE MADE BY THE COMMITTEE MEMBERS FOR ANY CHANGES/EDITS/ADDITIONS. AFTER THOSE HAVE BEEN INCORPORATED, THE AUDIT COMMITTEE VOTES WHETHER TO APPROVE AND THEN FORWARD THE 990 TO THE FINANCE AND EXECUTIVE COMMITTEES. THE FINANCE AND EXECUTIVE COMMITTEES PERFORM THE FINAL REVIEW AND THEN VOTE WHETHER TO APPROVE ON BEHALF OF THE BOARD OF DIRECTORS. A COPY OF THE APPROVED 990 IS SHARED WITH THE ENTIRE BOARD PRIOR TO ITS FILING WITH THE IRS.
FORM 990, PART VI, SECTION A, LINE 6	MEMBERSHIP IS AVAILABLE TO ANY PERSON WHO SUBSCRIBES TO THE PURPOSES AND OBJECTIVES OF THE CORPORATION, WITHOUT REGARD TO RACE, RELIGION, GENDER, SEXUAL ORIENTATION, AGE, COLOR, NATIONAL ORIGIN OR MENTAL OR PHYSICAL HANDICAP OR DISABILITY. THERE SHALL BE NO LIMIT TO THE NUMBER OF MEMBERS IN THE CORPORATION. 1) THERE MAY BE ONE OR MORE CLASSES OF MEMBERSHIP AS DETERMINED BY THE BOARD. 2) MEMBERSHIP IS NOT TRANSFERABLE OR ASSIGNABLE.
FORM 990, PART VI, SECTION A, LINE 7A	THE TSC ALLIANCE IS A MEMBERSHIP-BASED ORGANIZATION, WHICH MEANS MEMBERS HELP ELECT THE BOARD OF DIRECTORS. THE TSC ALLIANCE MEMBERSHIP PROGRAM ALLOWS INDIVIDUALS TO STATE THEIR INTENT TO BE A MEMBER FOR THE PURPOSE OF GOVERNANCE. THERE WERE NO LEVELS TO MEMBERSHIP IN 2021. ANYONE CAN BE A MEMBER AT NO COST.
FORM 990, PART VI, SECTION B, LINE 11B	THE FORM 990 IS REVIEWED, IN DETAIL, BY THE BOARD OF DIRECTORS' AUDIT COMMITTEE. RECOMMENDATIONS ARE MADE BY THE COMMITTEE MEMBERS FOR ANY CHANGES/EDITS/ADDITIONS. AFTER THOSE HAVE BEEN INCORPORATED, THE AUDIT COMMITTEE VOTES WHETHER TO APPROVE AND THEN FORWARD THE 990 TO THE FINANCE AND EXECUTIVE COMMITTEES. THE FINANCE AND EXECUTIVE COMMITTEES PERFORM THE FINAL REVIEW AND THEN VOTE WHETHER TO APPROVE ON BEHALF OF THE BOARD OF DIRECTORS. A COPY OF THE APPROVED 990 IS SHARED WITH THE ENTIRE BOARD PRIOR TO ITS FILING WITH THE IRS.
FORM 990, PART VI, SECTION B, LINE 12C	ANNUALLY EACH MEMBER OF THE BOARD OF DIRECTORS WILL RECEIVE NOTICE OF THE ORGANIZATION'S CONFLICT OF INTEREST STATEMENT. EACH MEMBER WILL BE PROVIDED WITH A STATEMENT TO MAKE DISCLOSURE OF ANY POTENTIAL CONFLICT OF INTEREST. IF DURING THE COURSE OF THE YEAR A POTENTIAL CONFLICT OF INTEREST ARISES THAT HAS NOT PREVIOUSLY BEEN DISCLOSED, THE BOARD MEMBER WILL MAKE WRITTEN NOTICE OF A POTENTIAL CONFLICT OF INTEREST AND RECUSE HIMSELF OR HERSELF FROM ANY DISCUSSIONS AND VOTES IN CONNECTION WITH THE ISSUE IDENTIFIED. ANY TIME A MEMBER IS RECUSED FROM DISCUSSION ON AN ISSUE, THE MINUTES OF COMMITTEE MEETING AND BOARD MEETING WILL DULY RECORD SUCH ACTIONS. THE FOLLOWING POTENTIAL CONFLICTS OF INTEREST WERE DISCLOSED FOR 2021: BOARD MEMBER MUSTAFA SAHIN, PH.D., M.D., IS EMPLOYED AT BOSTON CHILDREN'S HOSPITAL, WHICH RECEIVED $113,659 IN GRANTS AND $9,015 IN FEES FOR SERVICES FOR PARTICIPATION IN THE TSC NATURAL HISTORY DATABASE. BOARD MEMBER DARCY KRUEGER, MD, MPA, IS EMPLOYED AT THE CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER, WHICH RECEIVED A $100,000 GRANT PAYMENT FOR HIS WORK ON STOP-2 AND $8,190 IN FEES FOR SERVICES FOR PARTICIPATION IN THE TSC NATURAL HISTORY DATABASE. BOARD MEMBER JESSICA KREFTING, RN, IS EMPLOYED AT UNIVERSITY OF ALABAMA AT BIRMINGHAM, WHICH RECEIVED $7,715 IN FEES FOR SERVICES FOR PARTICIPATION IN THE TSC NATURAL HISTORY DATABASE. BOARD MEMBER AND CHAIR PETER CRINO, MD, PHD, IS CHAIR OF THE DEPARTMENT OF NEUROLOGY AT THE UNIVERSITY OF MD, WHICH RECIEVED A $18,634 GRANT PAYMENT.
FORM 990, PART VI, SECTION B, LINE 15	THE COMPENSATION COMMITTEE REVIEWS AND APPROVES THE SALARIES OF THE PRESIDENT/CEO, CHIEF SCIENTIFIC OFFICER, CFO, AND ANY EMPLOYEE APPEARING ON THE FORM 990, IN ACCORDANCE WITH THE TSC ALLIANCE BYLAWS. SUCH REVIEW AND APPROVAL OCCURS INITIALLY UPON HIRING, UPON ANNUAL REVIEWS, AND WHENEVER MODIFIED. THE ORGANIZATION'S EXECUTIVE REMUNERATION HAS BEEN STRUCTURED TO ENSURE THAT IT: IS REASONABLE; PROVIDES A COMPETITIVE COMPENSATION PROGRAM TO RETAIN, ATTRACT AND REWARD KEY EMPLOYEES AND ACHIEVES CLEAR ALIGNMENT BETWEEN TOTAL REMUNERATION AND DELIVERED BUSINESS AND PERSONAL PERFORMANCE OVER THE SHORT AND LONG-TERMS. THE COMPENSATION IS REVIEWED BY THE COMPENSATION COMMITTEE TO ENSURE: - COMPARABILITY, - PROPER REVIEW, AND - SUBSTANTIATION IN SETTING THE COMPENSATION.
FORM 990, PART VI, SECTION C, LINE 19	ALL GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY AND FINANCIAL STATEMENTS ARE AVAILABLE UPON WRITTEN REQUEST.

Schedule R IRS990ScheduleR

Id Related Tax Exempt Org IdRelatedTaxExemptOrgGrp

Disregarded Entity Name DisregardedEntityName

Field	Value	IRS element (for citing)
Business Name Line1	TSC ALLIANCE ENDOWMENT FUND INC	BusinessNameLine1Txt

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	8737 COLESVILLE ROAD NO 400	AddressLine1Txt
City	SILVER SPRING	CityNm
State Abbreviation	MD	StateAbbreviationCd
ZIP	20910	ZIPCd

Field	Value	IRS element (for citing)
EIN	521926919	EIN
Primary Activities	SUPPORT THE MISSION OF THE TSC ALLIANCE	PrimaryActivitiesTxt
Legal Domicile State	MD	LegalDomicileStateCd
Exempt Code Section	501(C)(3)	ExemptCodeSectionTxt
Public Charity Status	LINE 12B, II	PublicCharityStatusTxt
Direct Controlling NA	N/A	DirectControllingNACd
Controlled Organization	0	ControlledOrganizationInd

Field	Value	IRS element (for citing)
Receipt Of Int Annts Rnts Rylts	0	ReceiptOfIntAnntsRntsRyltsInd
Gift Grnt Or Cap Contri To Oth Org	0	GiftGrntOrCapContriToOthOrgInd
Gift Grnt Cap Contri From Oth Org	Yes (1)	GiftGrntCapContriFromOthOrgInd
Loans Or Guarantees To Other Org	0	LoansOrGuaranteesToOtherOrgInd
Loans Or Guarantees From Oth Org	0	LoansOrGuaranteesFromOthOrgInd
Div Related Organization	0	DivRelatedOrganizationInd
Asset Sale To Other Org	0	AssetSaleToOtherOrgInd
Asset Purchase From Other Org	0	AssetPurchaseFromOtherOrgInd
Asset Exchange	0	AssetExchangeInd
Rental Of Facilities To Oth Org	0	RentalOfFacilitiesToOthOrgInd
Rental Of Fclts From Oth Org	0	RentalOfFcltsFromOthOrgInd
Perform Of Services For Oth Org	0	PerformOfServicesForOthOrgInd
Perform Of Services By Other Org	0	PerformOfServicesByOtherOrgInd
Sharing Of Facilities	Yes (1)	SharingOfFacilitiesInd
Paid Employees Sharing	Yes (1)	PaidEmployeesSharingInd
Reimbursement Paid To Other Org	0	ReimbursementPaidToOtherOrgInd
Reimbursement Paid By Other Org	0	ReimbursementPaidByOtherOrgInd
Transfer To Other Org	0	TransferToOtherOrgInd
Transfer From Other Org	0	TransferFromOtherOrgInd

Transactions Related Org TransactionsRelatedOrgGrp

Other Organization Name OtherOrganizationName

Field	Value	IRS element (for citing)
Business Name Line1	TSC ALLIANCE ENDOWMENT FUND INC	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Transaction Type	C	TransactionTypeTxt
Involved	$226,000	InvolvedAmt
Method Of Amount Determination	CASH	MethodOfAmountDeterminationTxt