ALPHA-1 FOUNDATION INC: Form 990, tax year 2021

View the entire original 990 at ProPublica ↗

Organization
ALPHA-1 FOUNDATION INC (EIN 65-0585415)
Tax period
2021-07-01 to 2022-06-30
Filed
2023-02-16
IRS object ID
202330479349300533
Schema version
2021v4.2
Source
Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header ReturnHeader

FieldValueIRS element (for citing)
Return2023-02-16T11:06:52-06:00ReturnTs
Tax Period End2022-06-30TaxPeriodEndDt
Return Type990ReturnTypeCd
Tax Period Begin2021-07-01TaxPeriodBeginDt

Filer Filer

FieldValueIRS element (for citing)
EIN650585415EIN

Business Name BusinessName

FieldValueIRS element (for citing)
Business Name Line1Alpha-1 FoundationBusinessNameLine1Txt
Business Name Line2Alpha One FoundationBusinessNameLine2Txt
FieldValueIRS element (for citing)
In Care Of% Mark M DelvauxInCareOfNm
Business Name ControlALPHBusinessNameControlTxt
Phone3055679888PhoneNum

US Address USAddress

FieldValueIRS element (for citing)
Address Line13300 Ponce de Leon BoulevardAddressLine1Txt
CityMiamiCityNm
State AbbreviationFLStateAbbreviationCd
ZIP331347211ZIPCd

Business Officer BusinessOfficerGrp

FieldValueIRS element (for citing)
PersonMARK M DELVAUXPersonNm
Person TitleCFOPersonTitleTxt
Phone3055679888PhoneNum
Signature2023-02-16SignatureDt
Discuss With Paid PreparerfalseDiscussWithPaidPreparerInd

Signing Officer SigningOfficerGrp

Person Full Name PersonFullName

FieldValueIRS element (for citing)
Person FirstMARKPersonFirstNm
Person LastDELVAUXPersonLastNm
FieldValueIRS element (for citing)
SSNXXX-XX-XXXXSSN

Preparer Person PreparerPersonGrp

FieldValueIRS element (for citing)
Preparer PersonPATRICK M LUNNPreparerPersonNm
PTINP01874332PTIN
Phone3054421776PhoneNum
Preparation2023-02-16PreparationDt
Self EmployedYes (X)SelfEmployedInd

Additional Filer Information AdditionalFilerInformation

Trusted Customer TrustedCustomerGrp

FieldValueIRS element (for citing)
Trusted Customer2TrustedCustomerCd
Identity Assurance LevelIAL1IdentityAssuranceLevelCd
FieldValueIRS element (for citing)
Tax2021TaxYr
Build TS2023-03-07 01:45:13ZBuildTS

Form 990 IRS990

Doing Business As Name DoingBusinessAsName

FieldValueIRS element (for citing)
Business Name Line1Alpha One FoundationBusinessNameLine1Txt
FieldValueIRS element (for citing)
Principal OfficerMARK B DELVAUXPrincipalOfficerNm

US Address USAddress

FieldValueIRS element (for citing)
Address Line13300 Ponce de Leon BoulevardAddressLine1Txt
CityCoral GablesCityNm
State AbbreviationFLStateAbbreviationCd
ZIP33134ZIPCd
FieldValueIRS element (for citing)
Gross Receipts$17,207,677GrossReceiptsAmt
Group Return For AffiliatesfalseGroupReturnForAffiliatesInd
Organization501c3Yes (X)Organization501c3Ind
Website Addresswww.alpha1.orgWebsiteAddressTxt
Type Of Organization CorpYes (X)TypeOfOrganizationCorpInd
Formation1995FormationYr
Legal Domicile StateFLLegalDomicileStateCd
Activity Or MissionThe Alpha1 Foundation is committed to finding a cure for Alpha1 Antitrypsin Deficiency and to improving the lives of Alphas worldwideActivityOrMissionDesc
Voting Members Governing Body11VotingMembersGoverningBodyCnt
Voting Members Independent11VotingMembersIndependentCnt
Total Employee20TotalEmployeeCnt
Total Volunteers300TotalVolunteersCnt
Total Gross UBI$366,000TotalGrossUBIAmt
Net Unrelated Bus Txbl Incm$137,860NetUnrelatedBusTxblIncmAmt
PY Contributions Grants$7,939,893PYContributionsGrantsAmt
CY Contributions Grants$9,050,130CYContributionsGrantsAmt
PY Program Service Revenue$240,000PYProgramServiceRevenueAmt
CY Program Service Revenue$366,000CYProgramServiceRevenueAmt
PY Investment Income$2,701,074PYInvestmentIncomeAmt
CY Investment Income$1,460,203CYInvestmentIncomeAmt
PY Other Revenue$61,472PYOtherRevenueAmt
CY Other Revenue$13,751CYOtherRevenueAmt
PY Total Revenue$10,942,439PYTotalRevenueAmt
CY Total Revenue$10,890,084CYTotalRevenueAmt
PY Grants And Similar Paid$2,915,188PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid$2,583,468CYGrantsAndSimilarPaidAmt
CY Benefits Paid To Members$0CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid$1,734,769PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid$1,692,512CYSalariesCompEmpBnftPaidAmt
CY Total Prof Fndrsng Expns$0CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense$584,227CYTotalFundraisingExpenseAmt
PY Other Expenses$1,606,146PYOtherExpensesAmt
CY Other Expenses$2,088,226CYOtherExpensesAmt
PY Total Expenses$6,256,103PYTotalExpensesAmt
CY Total Expenses$6,364,206CYTotalExpensesAmt
PY Revenues Less Expenses$4,686,336PYRevenuesLessExpensesAmt
CY Revenues Less Expenses$4,525,878CYRevenuesLessExpensesAmt
Total Assets BOY$34,603,486TotalAssetsBOYAmt
Total Assets EOY$35,496,616TotalAssetsEOYAmt
Total Liabilities BOY$2,367,672TotalLiabilitiesBOYAmt
Total Liabilities EOY$2,623,720TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY$32,235,814NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY$32,872,896NetAssetsOrFundBalancesEOYAmt
Info In Schedule O Part IIIYes (X)InfoInScheduleOPartIIIInd
MissionThe Alpha-1 Foundation is committed to finding a cure for Alpha-1 Antitrypsin Deficiency and to improving the lives of people affected by Alpha-1 worldwide.MissionDesc
Significant New Program SrvcYes (true)SignificantNewProgramSrvcInd
Significant ChangefalseSignificantChangeInd
Expense$2,946,630ExpenseAmt
Grant$2,247,268GrantAmt
Revenue$1,760,096RevenueAmt
DescAlpha-1 Research Network: The Alpha-1 research infrastructure provides support for a network of Alpha-1 investigators worldwide. It is one of the Foundation's most valuable assets and includes the DNA & Tissue Bank, Therapeutic Development Network, and Clinical Resource Centers. The Foundation's mission is served by scientific meetings that bring together stakeholders with the intent to promote scientific discovery, identify new approaches to the detection of Alpha-1, and educate physicians and patients on Alpha-1. The Alpha-1 Grants and Awards program is the heart of the Foundation's research activities and has established itself as the worldwide leader of Alpha-1 research support.Desc

Prog Srvc Accom Acty2 ProgSrvcAccomActy2Grp

FieldValueIRS element (for citing)
Expense$443,089ExpenseAmt
Grant$257,700GrantAmt
Revenue$180,000RevenueAmt
DescAlpha-1 Registry and ACT Study: The Research Registry is a confidential database of diagnosed Alphas and carriers willing and able to participate in research studies and clinical trials for new therapies. It is comprised of both patient-supported and clinical data. The Registry represents the largest cohort of Alphas in the world. The goal of the Alpha-1 Coded Testing (ACT) Study is to provide a way for those at risk, including family members of diagnosed Alphas, to learn their genotype. The study includes a research questionnaire, a finger-stick testing kit, and is free and confidential.Desc

Prog Srvc Accom Acty3 ProgSrvcAccomActy3Grp

FieldValueIRS element (for citing)
Expense$305,120ExpenseAmt
Revenue$500,000RevenueAmt
DescAlpha-1 National Conference: The 31st annual Alpha-1 National Educational Conference was a hybrid conference held on June 8-11, 2022. As the largest annual gathering of the Alpha-1 community, the National Conference provides important opportunities for networking, education, and advocacy. The speakers included some of the leading clinicians and researchers in the Alpha-1 field to bring incredible subject matter expertise and education to the community. The program covered a wide range of medical education and supportive topics to inform, empower and motivate patients to take charge of their health. The last six years of presentations are available on the Foundation's website at www.alpha1.org.Desc

Prog Srvc Accom Acty Other ProgSrvcAccomActyOtherGrp (5 entries)

ExpenseExpenseAmtRevenueRevenueAmtDescDescGrantGrantAmt
$160,882$130,000The mission of Alpha-1 Global is to develop a collaborative global network of Alpha-1 patient leaders, physicians, and researchers.
$268,797$230,000The Foundation's Public Policy program monitors relevant legislation and regulatory issues and publicizes the Foundation's positions on such issues.
$227,140$366,000The Alpha-1-To-One Magazine is designed to inform the community of research developments, education, advocacy and fund raising opportunities.
$164,608$390,000Alpha-1 Education Days provide access to current medical information and resources to hundreds of Alphas, their families, and caregivers.
$561,694$333,500Other Alpha-1 services include patient education (materials, website, etc), a Patient Support Network, and a targeted detection program.$78,500
FieldValueIRS element (for citing)
Total Other Prog Srvc Expense$1,383,121TotalOtherProgSrvcExpenseAmt
Total Other Prog Srvc Grant$78,500TotalOtherProgSrvcGrantAmt
Total Other Prog Srvc Revenue$1,449,500TotalOtherProgSrvcRevenueAmt
Total Program Service Expenses$5,077,960TotalProgramServiceExpensesAmt
Described In Section501c3Yes (true)DescribedInSection501c3Ind
Schedule B RequiredYes (true)ScheduleBRequiredInd
Political Campaign ActyfalsePoliticalCampaignActyInd
Lobbying ActivitiesYes (true)LobbyingActivitiesInd
Subject To Proxy TaxfalseSubjectToProxyTaxInd
Donor Advised FundYes (true)DonorAdvisedFundInd
Conservation EasementsfalseConservationEasementsInd
Collections Of ArtfalseCollectionsOfArtInd
Credit CounselingfalseCreditCounselingInd
Donor Rstr Or Quasi EndowmentsfalseDonorRstrOrQuasiEndowmentsInd
Report Land Building EquipmentYes (true)ReportLandBuildingEquipmentInd
Report Investments Other SecfalseReportInvestmentsOtherSecInd
Report Program Related InvstfalseReportProgramRelatedInvstInd
Report Other AssetsfalseReportOtherAssetsInd
Report Other LiabilitiesYes (true)ReportOtherLiabilitiesInd
Include FIN48 FootnoteYes (true)IncludeFIN48FootnoteInd
Independent Audit Fincl StmtYes (true)IndependentAuditFinclStmtInd
Consolidated Audit Fincl StmtfalseConsolidatedAuditFinclStmtInd
School OperatingfalseSchoolOperatingInd
Foreign OfficefalseForeignOfficeInd
Foreign ActivitiesYes (true)ForeignActivitiesInd
More Than5000 K To OrgYes (true)MoreThan5000KToOrgInd
More Than5000 K To IndividualsYes (true)MoreThan5000KToIndividualsInd
Professional FundraisingfalseProfessionalFundraisingInd
Fundraising ActivitiesYes (true)FundraisingActivitiesInd
Gaming ActivitiesfalseGamingActivitiesInd
Operate HospitalfalseOperateHospitalInd
Grants To OrganizationsYes (true)GrantsToOrganizationsInd
Grants To IndividualsYes (true)GrantsToIndividualsInd
Schedule J RequiredYes (true)ScheduleJRequiredInd
Tax Exempt BondsfalseTaxExemptBondsInd
Engaged In Excess Benefit TransfalseEngagedInExcessBenefitTransInd
PY Excess Benefit TransfalsePYExcessBenefitTransInd
Loan OutstandingfalseLoanOutstandingInd
Grant To Related PersonfalseGrantToRelatedPersonInd
Business Rln With Org MemfalseBusinessRlnWithOrgMemInd
Business Rln With Fam MemfalseBusinessRlnWithFamMemInd
Business Rln With35 Ctrl EntfalseBusinessRlnWith35CtrlEntInd
Deductible Non Cash ContriYes (true)DeductibleNonCashContriInd
Deductible Art ContributionfalseDeductibleArtContributionInd
Terminate OperationsfalseTerminateOperationsInd
Partial LiquidationfalsePartialLiquidationInd
Disregarded EntityfalseDisregardedEntityInd
Related EntityYes (true)RelatedEntityInd
Related Organization Ctrl EntYes (true)RelatedOrganizationCtrlEntInd
Transaction With Control EntYes (true)TransactionWithControlEntInd
Trnsfr Exmpt Non Chrtbl Rltd OrgfalseTrnsfrExmptNonChrtblRltdOrgInd
Activities Conducted PrtshpfalseActivitiesConductedPrtshpInd
Schedule O RequiredYes (true)ScheduleORequiredInd
IRP Document20IRPDocumentCnt
IRP Document W2 G0IRPDocumentW2GCnt
Backup Wthld CompliancefalseBackupWthldComplianceInd
Employee20EmployeeCnt
Employment Tax Returns FiledYes (true)EmploymentTaxReturnsFiledInd
Unrelated Bus Incm Over LimitYes (true)UnrelatedBusIncmOverLimitInd
Form990 T FiledYes (true)Form990TFiledInd
Foreign Financial AccountfalseForeignFinancialAccountInd
Prohibited Tax Shelter TransfalseProhibitedTaxShelterTransInd
Taxable Party NotificationfalseTaxablePartyNotificationInd
Nondeductible ContributionsfalseNondeductibleContributionsInd
Quid Pro Quo ContributionsYes (true)QuidProQuoContributionsInd
Quid Pro Quo Contri DisclYes (true)QuidProQuoContriDisclInd
Form8282 Property Disposed OffalseForm8282PropertyDisposedOfInd
Rcv Fnds To Pay Prsnl Bnft CntrctfalseRcvFndsToPayPrsnlBnftCntrctInd
Pay Premiums Prsnl Bnft CntrctfalsePayPremiumsPrsnlBnftCntrctInd
Form8899 FiledindfalseForm8899Filedind
Form1098 C FiledfalseForm1098CFiledInd
DAF Excess Business HoldingsfalseDAFExcessBusinessHoldingsInd
Taxable DistributionsfalseTaxableDistributionsInd
Distribution To DonorfalseDistributionToDonorInd
Indoor Tanning ServicesfalseIndoorTanningServicesInd
Subj To Tax Rmnrtn Ex Prcht PymtfalseSubjToTaxRmnrtnExPrchtPymtInd
Subject To Excs Tax Net Invst IncfalseSubjectToExcsTaxNetInvstIncInd
Excs Tax Sect4951 Or4952 Or4953falseExcsTaxSect4951Or4952Or4953Ind
Info In Schedule O Part VIYes (X)InfoInScheduleOPartVIInd
Governing Body Voting Members11GoverningBodyVotingMembersCnt
Independent Voting Member11IndependentVotingMemberCnt
Family Or Business RlnfalseFamilyOrBusinessRlnInd
Delegation Of Mgmt DutiesfalseDelegationOfMgmtDutiesInd
Change To Org DocumentsfalseChangeToOrgDocumentsInd
Material Diversion Or MisusefalseMaterialDiversionOrMisuseInd
Members Or StockholdersfalseMembersOrStockholdersInd
Election Of Board MembersfalseElectionOfBoardMembersInd
Decisions Subject To ApprovafalseDecisionsSubjectToApprovaInd
Minutes Of Governing BodyYes (true)MinutesOfGoverningBodyInd
Minutes Of CommitteesYes (true)MinutesOfCommitteesInd
Officer Mailing AddressfalseOfficerMailingAddressInd
Local ChaptersfalseLocalChaptersInd
Form990 Provided To Gvrn BodyYes (true)Form990ProvidedToGvrnBodyInd
Conflict Of Interest PolicyYes (true)ConflictOfInterestPolicyInd
Annual Disclosure Covered PrsnYes (true)AnnualDisclosureCoveredPrsnInd
Regular Monitoring EnfrcYes (true)RegularMonitoringEnfrcInd
Whistleblower PolicyYes (true)WhistleblowerPolicyInd
Document Retention PolicyYes (true)DocumentRetentionPolicyInd
Compensation Process CEOYes (true)CompensationProcessCEOInd
Compensation Process OtherYes (true)CompensationProcessOtherInd
Investment In Joint VenturefalseInvestmentInJointVentureInd
States Where Copy Of Return Is FldALStatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is FldARStatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is FldCAStatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is FldCTStatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is FldFLStatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is FldGAStatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is FldHIStatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is FldILStatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is FldKSStatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is FldKYStatesWhereCopyOfReturnIsFldCd
Own WebsiteYes (X)OwnWebsiteInd
Upon RequestYes (X)UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

FieldValueIRS element (for citing)
PersonMARK B DELVAUXPersonNm
Phone3055679888PhoneNum

US Address USAddress

FieldValueIRS element (for citing)
Address Line13300 Ponce de Leon BoulevardAddressLine1Txt
CityCoral GablesCityNm
State AbbreviationFLStateAbbreviationCd
ZIP33134ZIPCd
FieldValueIRS element (for citing)
Info In Schedule O Part VIIYes (X)InfoInScheduleOPartVIIInd

Form990 Part VII Section A Form990PartVIISectionAGrp (17 entries)

TitleTitleTxtAverage Hours Per WeekAverageHoursPerWeekRtOfficerOfficerIndReportable Comp From OrgReportableCompFromOrgAmtReportable Comp From Rltd OrgReportableCompFromRltdOrgAmtOther CompensationOtherCompensationAmtHighest Compensated EmployeeHighestCompensatedEmployeeIndFormer Ofcr Director TrusteeFormerOfcrDirectorTrusteeIndIndividual Trustee Or DirectorIndividualTrusteeOrDirectorInd
SCOTT T SANTARELLA
President and CEO40.00Yes (X)$76,853$0$491
RANDEL H PLANT
Sen Dir Research Progs40.00$129,239$0$11,915Yes (X)
ANGELA T MCBRIDE
Sen Dir Corp Relations40.00$115,193$0$15,483Yes (X)
MIRIAM A O'DAY
President and CEO40.00$187,865$0$3,695Yes (X)
LINDA M RODRIGUEZ
Senior Dir Development40.00$104,627$0$2,578Yes (X)
JEANINE D'ARMIENTO
Immediate Past Chair8.000Yes (X)$0$0$0Yes (X)
ELIZABETH JOHNSON
Director4.000$0$0$0Yes (X)
FRED C WALSH
Vice Chair8.000Yes (X)$0$0$0Yes (X)
JON HAGSTROM
Chair8.000Yes (X)$0$0$0Yes (X)
KENNETH IRVINE
Treasurer8.000Yes (X)$0$0$0Yes (X)
PEGGY IVERSON
Director4.000$0$0$0Yes (X)
ANN KNEBEL
Secretary8.000Yes (X)$0$0$0Yes (X)
NOEL G MCELVANEY
Director4.000$0$0$0Yes (X)
FARON SCHONFELD
Director4.000$0$0$0Yes (X)
JAMES K STOLLER
Director4.000$0$0$0Yes (X)
CATHERINE VERNON
Director4.000$0$0$0Yes (X)
MARK B DELVAUX
CFO10.00Yes (X)$0$0$0
FieldValueIRS element (for citing)
Total Reportable Comp From Org$613,777TotalReportableCompFromOrgAmt
Total Other Compensation$34,162TotalOtherCompensationAmt
Indiv Rcvd Greater Than100 K4IndivRcvdGreaterThan100KCnt
Former Ofcr Employees ListedYes (true)FormerOfcrEmployeesListedInd
Total Comp Greater Than150 KYes (true)TotalCompGreaterThan150KInd
Compensation From Other SrcsYes (true)CompensationFromOtherSrcsInd

Contractor Compensation ContractorCompensationGrp (2 entries)

Address Line1ContractorAddress/USAddress/AddressLine1TxtCityContractorAddress/USAddress/CityNmState AbbreviationContractorAddress/USAddress/StateAbbreviationCdZIPContractorAddress/USAddress/ZIPCdServicesServicesDescCompensationCompensationAmt
AlphaNet Inc
3300 Ponce de Leon BoulevardCoral GablesFL33134Management services$194,680
Original Impressions LLC
PO Box 31792 Dept 18890TampaFL33631Printing and publication$115,769
FieldValueIRS element (for citing)
Cntrct Rcvd Greater Than100 K2CntrctRcvdGreaterThan100KCnt
All Other Contributions$9,050,130AllOtherContributionsAmt
Noncash Contributions$216,394NoncashContributionsAmt
Total Contributions$9,050,130TotalContributionsAmt

Program Service Revenue ProgramServiceRevenueGrp

FieldValueIRS element (for citing)
DescPublication incomeDesc
Business511120BusinessCd
Total Revenue Column$366,000TotalRevenueColumnAmt
Unrelated Business Revenue$366,000UnrelatedBusinessRevenueAmt
FieldValueIRS element (for citing)
Total Program Service Revenue$366,000TotalProgramServiceRevenueAmt

Investment Income InvestmentIncomeGrp

FieldValueIRS element (for citing)
Total Revenue Column$465,635TotalRevenueColumnAmt
Related Or Exempt Func Income$465,635RelatedOrExemptFuncIncomeAmt

Gross Rents GrossRentsGrp

FieldValueIRS element (for citing)
Real$8,788RealAmt

Rental Income Or Loss RentalIncomeOrLossGrp

FieldValueIRS element (for citing)
Real$8,788RealAmt

Net Rental Income Or Loss NetRentalIncomeOrLossGrp

FieldValueIRS element (for citing)
Total Revenue Column$8,788TotalRevenueColumnAmt
Related Or Exempt Func Income$8,788RelatedOrExemptFuncIncomeAmt

Gross Amount Sales Assets GrossAmountSalesAssetsGrp

FieldValueIRS element (for citing)
Securities$7,267,974SecuritiesAmt

Less Cost Oth Basis Sales Expnss LessCostOthBasisSalesExpnssGrp

FieldValueIRS element (for citing)
Securities$6,273,406SecuritiesAmt

Gain Or Loss GainOrLossGrp

FieldValueIRS element (for citing)
Securities$994,568SecuritiesAmt

Net Gain Or Loss Investments NetGainOrLossInvestmentsGrp

FieldValueIRS element (for citing)
Total Revenue Column$994,568TotalRevenueColumnAmt
Related Or Exempt Func Income$994,568RelatedOrExemptFuncIncomeAmt
FieldValueIRS element (for citing)
Fundraising Gross Income$49,150FundraisingGrossIncomeAmt
Fundraising Direct Expenses$44,187FundraisingDirectExpensesAmt

Net Incm From Fundraising Evt NetIncmFromFundraisingEvtGrp

FieldValueIRS element (for citing)
Total Revenue Column$4,963TotalRevenueColumnAmt
Exclusion$4,963ExclusionAmt

Total Revenue TotalRevenueGrp

FieldValueIRS element (for citing)
Total Revenue Column$10,890,084TotalRevenueColumnAmt
Related Or Exempt Func Income$1,468,991RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue$366,000UnrelatedBusinessRevenueAmt
Exclusion$4,963ExclusionAmt
FieldValueIRS element (for citing)
Info In Schedule O Part IXYes (X)InfoInScheduleOPartIXInd

Grants To Domestic Orgs GrantsToDomesticOrgsGrp

FieldValueIRS element (for citing)
Total$1,723,851TotalAmt
Program Services$1,723,851ProgramServicesAmt

Grants To Domestic Individuals GrantsToDomesticIndividualsGrp

FieldValueIRS element (for citing)
Total$53,500TotalAmt
Program Services$53,500ProgramServicesAmt

Foreign Grants ForeignGrantsGrp

FieldValueIRS element (for citing)
Total$806,117TotalAmt
Program Services$806,117ProgramServicesAmt

Other Salaries And Wages OtherSalariesAndWagesGrp

FieldValueIRS element (for citing)
Total$1,369,894TotalAmt
Program Services$1,010,855ProgramServicesAmt
Management And General$83,978ManagementAndGeneralAmt
Fundraising$275,061FundraisingAmt

Pension Plan Contributions PensionPlanContributionsGrp

FieldValueIRS element (for citing)
Total$18,789TotalAmt
Program Services$13,510ProgramServicesAmt
Management And General$1,833ManagementAndGeneralAmt
Fundraising$3,446FundraisingAmt

Other Employee Benefits OtherEmployeeBenefitsGrp

FieldValueIRS element (for citing)
Total$200,345TotalAmt
Program Services$155,670ProgramServicesAmt
Management And General$6,952ManagementAndGeneralAmt
Fundraising$37,723FundraisingAmt

Payroll Taxes PayrollTaxesGrp

FieldValueIRS element (for citing)
Total$103,484TotalAmt
Program Services$75,616ProgramServicesAmt
Management And General$6,772ManagementAndGeneralAmt
Fundraising$21,096FundraisingAmt

Fees For Services Management FeesForServicesManagementGrp

FieldValueIRS element (for citing)
Total$220,000TotalAmt
Program Services$120,000ProgramServicesAmt
Management And General$100,000ManagementAndGeneralAmt

Fees For Services Legal FeesForServicesLegalGrp

FieldValueIRS element (for citing)
Total$115,164TotalAmt
Program Services$89,736ProgramServicesAmt
Management And General$25,428ManagementAndGeneralAmt

Fees For Services Accounting FeesForServicesAccountingGrp

FieldValueIRS element (for citing)
Total$63,779TotalAmt
Management And General$63,779ManagementAndGeneralAmt

Fees For Services Lobbying FeesForServicesLobbyingGrp

FieldValueIRS element (for citing)
Total$10,000TotalAmt
Program Services$10,000ProgramServicesAmt

Fees For Srvc Invst Mgmnt Fees FeesForSrvcInvstMgmntFeesGrp

FieldValueIRS element (for citing)
Total$146,362TotalAmt
Management And General$146,362ManagementAndGeneralAmt

Fees For Services Other FeesForServicesOtherGrp

FieldValueIRS element (for citing)
Total$358,316TotalAmt
Program Services$283,073ProgramServicesAmt
Management And General$67,961ManagementAndGeneralAmt
Fundraising$7,282FundraisingAmt

Office Expenses OfficeExpensesGrp

FieldValueIRS element (for citing)
Total$419,293TotalAmt
Program Services$298,119ProgramServicesAmt
Management And General$29,772ManagementAndGeneralAmt
Fundraising$91,402FundraisingAmt

Information Technology InformationTechnologyGrp

FieldValueIRS element (for citing)
Total$79,249TotalAmt
Program Services$51,797ProgramServicesAmt
Management And General$20,152ManagementAndGeneralAmt
Fundraising$7,300FundraisingAmt

Occupancy OccupancyGrp

FieldValueIRS element (for citing)
Total$219,483TotalAmt
Program Services$161,958ProgramServicesAmt
Management And General$13,455ManagementAndGeneralAmt
Fundraising$44,070FundraisingAmt

Travel TravelGrp

FieldValueIRS element (for citing)
Total$36,102TotalAmt
Program Services$17,863ProgramServicesAmt
Management And General$16,189ManagementAndGeneralAmt
Fundraising$2,050FundraisingAmt

Conferences Meetings ConferencesMeetingsGrp

FieldValueIRS element (for citing)
Total$153,092TotalAmt
Program Services$102,826ProgramServicesAmt
Management And General$46,273ManagementAndGeneralAmt
Fundraising$3,993FundraisingAmt

Depreciation Depletion DepreciationDepletionGrp

FieldValueIRS element (for citing)
Total$8,766TotalAmt
Program Services$6,468ProgramServicesAmt
Management And General$538ManagementAndGeneralAmt
Fundraising$1,760FundraisingAmt

Insurance InsuranceGrp

FieldValueIRS element (for citing)
Total$36,235TotalAmt
Program Services$18,196ProgramServicesAmt
Management And General$13,097ManagementAndGeneralAmt
Fundraising$4,942FundraisingAmt

Other Expenses OtherExpensesGrp (3 entries)

DescDescTotalTotalAmtProgram ServicesProgramServicesAmtManagement And GeneralManagementAndGeneralAmtFundraisingFundraisingAmt
Telephones$22,715$16,583$894$5,238
Dues and Subscriptions$126,145$62,222$19,136$44,787
Licenses, Fees and Taxes$73,525$39,448$34,077

Total Functional Expenses TotalFunctionalExpensesGrp

FieldValueIRS element (for citing)
Total$6,364,206TotalAmt
Program Services$5,077,960ProgramServicesAmt
Management And General$702,019ManagementAndGeneralAmt
Fundraising$584,227FundraisingAmt

Cash Non Interest Bearing CashNonInterestBearingGrp

FieldValueIRS element (for citing)
BOY$4,319,457BOYAmt
EOY$7,943,740EOYAmt

Savings And Temp Cash Invst SavingsAndTempCashInvstGrp

FieldValueIRS element (for citing)
BOY$4,294,626BOYAmt
EOY$4,433,622EOYAmt

Accounts Receivable AccountsReceivableGrp

FieldValueIRS element (for citing)
BOY$982,721BOYAmt
EOY$675,118EOYAmt

Prepaid Expenses Defrd Charges PrepaidExpensesDefrdChargesGrp

FieldValueIRS element (for citing)
BOY$21,728BOYAmt
EOY$167,500EOYAmt
FieldValueIRS element (for citing)
Land Bldg Equip Cost Or Other Bss$414,903LandBldgEquipCostOrOtherBssAmt
Land Bldg Equip Accum Deprec$401,921LandBldgEquipAccumDeprecAmt

Land Bldg Equip Basis Net LandBldgEquipBasisNetGrp

FieldValueIRS element (for citing)
BOY$21,749BOYAmt
EOY$12,982EOYAmt

Investments Pub Traded Sec InvestmentsPubTradedSecGrp

FieldValueIRS element (for citing)
BOY$24,801,956BOYAmt
EOY$21,875,585EOYAmt

Investments Program Related InvestmentsProgramRelatedGrp

FieldValueIRS element (for citing)
BOY$136,115BOYAmt
EOY$363,069EOYAmt

Other Assets Total OtherAssetsTotalGrp

FieldValueIRS element (for citing)
BOY$25,134BOYAmt
EOY$25,000EOYAmt

Total Assets TotalAssetsGrp

FieldValueIRS element (for citing)
BOY$34,603,486BOYAmt
EOY$35,496,616EOYAmt

Accounts Payable Accr Expnss AccountsPayableAccrExpnssGrp

FieldValueIRS element (for citing)
BOY$1,937,857BOYAmt
EOY$1,889,700EOYAmt

Deferred Revenue DeferredRevenueGrp

FieldValueIRS element (for citing)
BOY$416,000BOYAmt
EOY$715,000EOYAmt

Other Liabilities OtherLiabilitiesGrp

FieldValueIRS element (for citing)
BOY$13,815BOYAmt
EOY$19,020EOYAmt

Total Liabilities TotalLiabilitiesGrp

FieldValueIRS element (for citing)
BOY$2,367,672BOYAmt
EOY$2,623,720EOYAmt
FieldValueIRS element (for citing)
Organization Follows FASB117Yes (X)OrganizationFollowsFASB117Ind

No Donor Restriction Net Assets NoDonorRestrictionNetAssetsGrp

FieldValueIRS element (for citing)
BOY$29,114,292BOYAmt
EOY$29,569,884EOYAmt

Donor Restriction Net Assets DonorRestrictionNetAssetsGrp

FieldValueIRS element (for citing)
BOY$3,121,522BOYAmt
EOY$3,303,012EOYAmt

Total Net Assets Fund Balance TotalNetAssetsFundBalanceGrp

FieldValueIRS element (for citing)
BOY$32,235,814BOYAmt
EOY$32,872,896EOYAmt

Tot Liab Net Assets Fund Balance TotLiabNetAssetsFundBalanceGrp

FieldValueIRS element (for citing)
BOY$34,603,486BOYAmt
EOY$35,496,616EOYAmt
FieldValueIRS element (for citing)
Info In Schedule O Part XIYes (X)InfoInScheduleOPartXIInd
Reconcilation Revenue Expnss$4,525,878ReconcilationRevenueExpnssAmt
Net Unrlzd Gains Losses Invst-$4,115,749NetUnrlzdGainsLossesInvstAmt
Other Changes In Net Assets$226,953OtherChangesInNetAssetsAmt
Method Of Accounting AccrualYes (X)MethodOfAccountingAccrualInd
Accountant Compile Or ReviewfalseAccountantCompileOrReviewInd
FS AuditedYes (true)FSAuditedInd

FS Audited Basis FSAuditedBasisGrp

FieldValueIRS element (for citing)
Consolidated Basis Fincl StmtYes (X)ConsolidatedBasisFinclStmtInd
FieldValueIRS element (for citing)
Audit CommitteeYes (true)AuditCommitteeInd
Federal Grant Audit RequiredfalseFederalGrantAuditRequiredInd

Schedule A IRS990ScheduleA

FieldValueIRS element (for citing)
Public Organization170Yes (X)PublicOrganization170Ind

Gifts Grants Contri Rcvd170 GiftsGrantsContriRcvd170Grp

FieldValueIRS element (for citing)
Current Tax Year Minus4 Years$7,669,714CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years$8,335,339CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years$7,936,556CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year$7,939,893CurrentTaxYearMinus1YearAmt
Current Tax Year$9,050,130CurrentTaxYearAmt
Total$40,931,632TotalAmt

Total Calendar Year170 TotalCalendarYear170Grp

FieldValueIRS element (for citing)
Current Tax Year Minus4 Years$7,669,714CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years$8,335,339CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years$7,936,556CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year$7,939,893CurrentTaxYearMinus1YearAmt
Current Tax Year$9,050,130CurrentTaxYearAmt
Total$40,931,632TotalAmt
FieldValueIRS element (for citing)
Substantial Contributors Tot$28,336,460SubstantialContributorsTotAmt
Public Support Total170$12,595,172PublicSupportTotal170Amt

Gross Investment Income170 GrossInvestmentIncome170Grp

FieldValueIRS element (for citing)
Current Tax Year Minus4 Years$493,565CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years$507,839CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years$512,763CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year$469,516CurrentTaxYearMinus1YearAmt
Current Tax Year$474,423CurrentTaxYearAmt
Total$2,458,106TotalAmt

Unrelated Business Net Incm170 UnrelatedBusinessNetIncm170Grp

FieldValueIRS element (for citing)
Current Tax Year Minus4 Years$104,576CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years$17,767CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years$73,156CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year$62,038CurrentTaxYearMinus1YearAmt
Current Tax Year$137,860CurrentTaxYearAmt
Total$395,397TotalAmt
FieldValueIRS element (for citing)
Total Support$43,785,135TotalSupportAmt
Public Support CY1700.28766PublicSupportCY170Pct
Public Support PY1700.27184PublicSupportPY170Pct
Ten Pct Facts Crcmstncs Test CYYes (X)TenPctFactsCrcmstncsTestCYInd

Form990 Schedule A Part VI Form990ScheduleAPartVIGrp (18 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Part II, Line 17The Alpha-1 Foundation maintains an ongoing solicitation program
Part II, Line 17from the general public. During the fiscal year ended June 30,
Part II, Line 172022, the Foundation received 3,867 contributions from donors
Part II, Line 17from across the United States. As shown on Schedule B, 52 donors
Part II, Line 17contributed amounts of $5,000 or higher. Fund raising activities
Part II, Line 17include a general campaign, special events, and other fund
Part II, Line 17raising appeals. The public support percentage for fiscal 2022
Part II, Line 17would be above 35% if the support received from AlphaNet, Inc.,
Part II, Line 17a Section 501(c)(3) Type 2 charity, was excluded from this
Part II, Line 17computation. The support received from AlphaNet has provided
Part II, Line 17funding to support detection of Alpha-1 affected persons,
Part II, Line 17research for improved therapies, and a cure for Alpha-1. The
Part II, Line 17Board of Directors is comprised of 11 individuals, geographically
Part II, Line 17distributed across the United States and abroad, including 6
Part II, Line 17members who have been diagnosed with Alpha-1, 1 who had a family
Part II, Line 17member diagnosed with Alpha-1, 1 registered nurse, and 3 medical
Part II, Line 17doctors who are experts in the field. All members are
Part II, Line 17independent.

Schedule B IRS990ScheduleB

Contributor Information ContributorInformationGrp

FieldValueIRS element (for citing)
ContributorRESTRICTEDContributorNum

Contributor Business Name ContributorBusinessName

FieldValueIRS element (for citing)
Business Name Line1RESTRICTEDBusinessNameLine1

Contributor US Address ContributorUSAddress

FieldValueIRS element (for citing)
Address Line1RESTRICTEDAddressLine1
Address Line2RESTRICTEDAddressLine2
CityRESTRICTEDCity
StateRESTRICTEDState
ZIP CodeRESTRICTEDZIPCode
FieldValueIRS element (for citing)
Total ContributionsRESTRICTEDTotalContributionsAmt

Schedule C IRS990ScheduleC

Total Grassroots Lobbying TotalGrassrootsLobbyingGrp

FieldValueIRS element (for citing)
Filing Organizations Total$10,000FilingOrganizationsTotalAmt

Total Lobbying Expend TotalLobbyingExpendGrp

FieldValueIRS element (for citing)
Filing Organizations Total$10,000FilingOrganizationsTotalAmt

Other Exempt Purpose Expend OtherExemptPurposeExpendGrp

FieldValueIRS element (for citing)
Filing Organizations Total$6,364,206FilingOrganizationsTotalAmt

Total Exempt Purpose Expend TotalExemptPurposeExpendGrp

FieldValueIRS element (for citing)
Filing Organizations Total$6,374,206FilingOrganizationsTotalAmt

Lobbying Nontaxable Amount LobbyingNontaxableAmountGrp

FieldValueIRS element (for citing)
Filing Organizations Total$468,710FilingOrganizationsTotalAmt

Grassroots Nontaxable GrassrootsNontaxableGrp

FieldValueIRS element (for citing)
Filing Organizations Total$117,178FilingOrganizationsTotalAmt
FieldValueIRS element (for citing)
Form4720 FiledfalseForm4720FiledInd

Avg Lobbying Nontaxable Amount AvgLobbyingNontaxableAmountGrp

FieldValueIRS element (for citing)
Current Year Minus3$540,927CurrentYearMinus3Amt
Current Year Minus2$451,409CurrentYearMinus2Amt
Current Year Minus1$462,805CurrentYearMinus1Amt
Current Year$468,710CurrentYearAmt
Total$1,923,851TotalAmt
FieldValueIRS element (for citing)
Lobbying Ceiling$2,885,777LobbyingCeilingAmt

Avg Total Lobbying Expend AvgTotalLobbyingExpendGrp

FieldValueIRS element (for citing)
Current Year Minus3$10,000CurrentYearMinus3Amt
Current Year Minus2$10,000CurrentYearMinus2Amt
Current Year Minus1$10,000CurrentYearMinus1Amt
Current Year$10,000CurrentYearAmt
Total$40,000TotalAmt

Avg Grassroots Nontaxable AvgGrassrootsNontaxableGrp

FieldValueIRS element (for citing)
Current Year Minus3$135,232CurrentYearMinus3Amt
Current Year Minus2$112,852CurrentYearMinus2Amt
Current Year Minus1$115,701CurrentYearMinus1Amt
Current Year$117,178CurrentYearAmt
Total$480,963TotalAmt
FieldValueIRS element (for citing)
Grassroots Ceiling$721,445GrassrootsCeilingAmt

Avg Grassroots Lobbying Expend AvgGrassrootsLobbyingExpendGrp

FieldValueIRS element (for citing)
Current Year Minus3$10,000CurrentYearMinus3Amt
Current Year Minus2$10,000CurrentYearMinus2Amt
Current Year Minus1$10,000CurrentYearMinus1Amt
Current Year$10,000CurrentYearAmt
Total$40,000TotalAmt
FieldValueIRS element (for citing)
VolunteersfalseVolunteersInd
Paid Staff Or ManagementfalsePaidStaffOrManagementInd
Media AdvertisementsfalseMediaAdvertisementsInd
Mailings MembersfalseMailingsMembersInd
Publications Or BroadcastfalsePublicationsOrBroadcastInd
Grants Other OrganizationsfalseGrantsOtherOrganizationsInd
Direct Contact LegislatorsfalseDirectContactLegislatorsInd
Rallies DemonstrationsfalseRalliesDemonstrationsInd
Other ActivitiesfalseOtherActivitiesInd
Not Described Section501c3falseNotDescribedSection501c3Ind
Form4720 Filed4912 TaxfalseForm4720Filed4912TaxInd

Schedule D IRS990ScheduleD

FieldValueIRS element (for citing)
Donor Advised Funds Held1DonorAdvisedFundsHeldCnt
Donor Advised Funds Vl EOY$28,369DonorAdvisedFundsVlEOYAmt
Disclosed Org Leg CtrlYes (true)DisclosedOrgLegCtrlInd
Disclosed For Charitable PrpsYes (true)DisclosedForCharitablePrpsInd
Written Policy MonitoringfalseWrittenPolicyMonitoringInd
Section170h Rqr StsfdfalseSection170hRqrStsfdInd
Solicited Assets SalefalseSolicitedAssetsSaleInd
Agent Trustee EtcfalseAgentTrusteeEtcInd
Incl Escrow Custodial Acct LiabfalseInclEscrowCustodialAcctLiabInd

Leasehold Improvements LeaseholdImprovementsGrp

FieldValueIRS element (for citing)
Investment Cost Or Other Basis$200,825InvestmentCostOrOtherBasisAmt
Depreciation$200,825DepreciationAmt

Equipment EquipmentGrp

FieldValueIRS element (for citing)
Investment Cost Or Other Basis$214,078InvestmentCostOrOtherBasisAmt
Depreciation$201,096DepreciationAmt
Book Value$12,982BookValueAmt
FieldValueIRS element (for citing)
Total Book Value Land Buildings$12,982TotalBookValueLandBuildingsAmt

Invst Program Related Org InvstProgramRelatedOrgGrp

FieldValueIRS element (for citing)
DescThe Alpha1 ProjectDesc
Book Value$363,069BookValueAmt
Method ValuationCMethodValuationCd
FieldValueIRS element (for citing)
Total Book Value Program Rltd$363,069TotalBookValueProgramRltdAmt

Other Assets Org OtherAssetsOrgGrp

FieldValueIRS element (for citing)
DescDepositsDesc
Book Value$25,000BookValueAmt
FieldValueIRS element (for citing)
Total Book Value Other Assets$25,000TotalBookValueOtherAssetsAmt
Federal Income Tax Liability$19,020FederalIncomeTaxLiabilityAmt
Total Liability$19,020TotalLiabilityAmt
Footnote TextYes (X)FootnoteTextInd
Total Rev Etc Audited Fincl Stmt$6,672,159TotalRevEtcAuditedFinclStmtAmt
Net Unrealized Gains Invst-$4,115,749NetUnrealizedGainsInvstAmt
Other Revenue-$1OtherRevenueAmt
Revenue Not Reported-$4,115,750RevenueNotReportedAmt
Revenue Subtotal$10,787,909RevenueSubtotalAmt
Investment Expenses Not Incld$146,362InvestmentExpensesNotIncldAmt
Other Revenues Not Included-$44,187OtherRevenuesNotIncludedAmt
Revenue Not Reported Fincl Stmt$102,175RevenueNotReportedFinclStmtAmt
Total Revenue Per Form990$10,890,084TotalRevenuePerForm990Amt
Tot Expns Etc Audited Fincl Stmt$6,262,031TotExpnsEtcAuditedFinclStmtAmt
Other Expenses Included$44,187OtherExpensesIncludedAmt
Expenses Not Reported$44,187ExpensesNotReportedAmt
Expenses Subtotal$6,217,844ExpensesSubtotalAmt
Investment Expenses Not Incld2$146,362InvestmentExpensesNotIncld2Amt
Expenses Not Rpt Fincl Stmt$146,362ExpensesNotRptFinclStmtAmt
Total Expenses Per Form990$6,364,206TotalExpensesPerForm990Amt

Supplemental Information Detail SupplementalInformationDetail (15 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
P10, Ln 2The Foundation has adopted the provisions of ASC No. 740 "Income Taxes."
P10, Ln 2Under ASC 740, the Foundation must recognize the tax liability (or benefit)
P10, Ln 2associated with tax positions taken for tax return purposes when it is
P10, Ln 2more-likely-than-not that the position will be sustained. The adoption of
P10, Ln 2ASC 740 had no impact on the Foundation's consolidated financial
P10, Ln 2statements. Management of the Foundation does not believe there are any
P10, Ln 2material uncertain tax positions and accordingly has not recorded any
P10, Ln 2liability for unrecognized tax benefits.
P11, Ln 4bThis amount reflects special event expenses that are reported at gross in
P11, Ln 4bthe audited financial statements, rather than netted against special event
P11, Ln 4brevenues as is the case on the Form 990.
P12, Ln 2dThis amount reflects special event expenses that are reported at gross in
P12, Ln 2dthe audited financial statements, rather than netted against special event
P12, Ln 2drevenues as is the case on the Form 990.
P11, Ln 2dThis amount is an adjustment for rounding.

Schedule F IRS990ScheduleF

FieldValueIRS element (for citing)
Grant Records MaintainedYes (true)GrantRecordsMaintainedInd

Account Activities Outside US AccountActivitiesOutsideUSGrp

FieldValueIRS element (for citing)
RegionEuropeRegionTxt
Offices0OfficesCnt
Employee1EmployeeCnt
Type Of Activities ConductedProgram servicesTypeOfActivitiesConductedTxt
Specific Services ProvidedEuropean public policySpecificServicesProvidedTxt
Region Total Expenditures$41,027RegionTotalExpendituresAmt
FieldValueIRS element (for citing)
Subtotal Employees1SubtotalEmployeesCnt
Total Employee1TotalEmployeeCnt
Subtotal Spent$41,027SubtotalSpentAmt
Total Spent$41,027TotalSpentAmt

Grants To Org Outside US GrantsToOrgOutsideUSGrp (11 entries)

RegionRegionTxtPurpose Of GrantPurposeOfGrantTxtCash GrantCashGrantAmtManner Of Cash DisbursementMannerOfCashDisbursementTxt
EuropeResearch$99,000Wire
EuropeResearch$89,000Wire
EuropeResearch$99,000Wire
EuropeResearch$78,000Wire
EuropeResearch$99,583Wire
EuropeResearch$100,000Wire
East Asia and the PacificResearch$100,000Wire
EuropeResearch$18,750Wire
EuropeResearch$9,617Wire
EuropeResearch$13,167Wire
EuropeResearch$100,000Wire
FieldValueIRS element (for citing)
Total501c3 Org11Total501c3OrgCnt
Transfer To Foreign CorpfalseTransferToForeignCorpInd
Interest In Foreign TrustfalseInterestInForeignTrustInd
Foreign Corp OwnershipfalseForeignCorpOwnershipInd
Passive Foreign Investmest CofalsePassiveForeignInvestmestCoInd
Foreign PartnershipfalseForeignPartnershipInd
Boycott CountriesfalseBoycottCountriesInd

Supplemental Information Detail SupplementalInformationDetail (3 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
P1, Ln 2Please see Schedule I, Part IV. The grant-making processes are the same as
P1, Ln 2those for organizations in the United States.
P1, Ln 3, Col FThe organization uses accrual accounting for its grants paid.

Schedule G IRS990ScheduleG

Fundraising Event Information FundraisingEventInformationGrp

FieldValueIRS element (for citing)
Event1TournamentEvent1Nm
Gross Receipts Event1$49,150GrossReceiptsEvent1Amt
Gross Revenue Event1$49,150GrossRevenueEvent1Amt
Rent Facility Costs Event1$44,187RentFacilityCostsEvent1Amt
Gross Receipts Total$49,150GrossReceiptsTotalAmt
Gross Revenue Total Events$49,150GrossRevenueTotalEventsAmt
Rent Fclty Costs Total Events$44,187RentFcltyCostsTotalEventsAmt
Direct Expense Summary Events$44,187DirectExpenseSummaryEventsAmt
Net Income Summary$4,963NetIncomeSummaryAmt

Schedule I IRS990ScheduleI

FieldValueIRS element (for citing)
Grant Records MaintainedYes (true)GrantRecordsMaintainedInd

Recipient Table RecipientTable (16 entries)

Address Line1USAddress/AddressLine1TxtCityUSAddress/CityNmState AbbreviationUSAddress/StateAbbreviationCdZIPUSAddress/ZIPCdRecipient EINRecipientEINIRC SectionIRCSectionDescCash GrantCashGrantAmtNon Cash AssistanceNonCashAssistanceAmtPurpose Of GrantPurposeOfGrantTxt
University of Florida
PO Box 113001GainesvilleFL32611596002052501c3$441,615$0Research
Columbia University
630 West 168th St Ste 39New YorkNY10027135598093501c3$300,000$0Research
Clemson University
105 Sikes HallClemsonSC29634576000254501c3$74,000$0Research
University of Kentucky
741 South Limestone Ste B259LexingtonKY40536616033693501c3$94,340$0Research
National Jewish Health
1400 Jackson StDenverCO80206742044647501c3$124,873$0Research
Northwestern University
303 E Chicago AveChicagoIL60611362167817501c3$67,850$0Research
University of Alabama
1720 2nd Avenue South Ste AB 1170BirminghamAL35294636001138501c3$74,000$0Research
Saint Louis University
1100 South Grand BoulevardSaint LouisMO63103430654872501c3$81,996$0Research
University of Colorado
1600 BroadwayDenverCO80202846000555501c3$15,628$0Research
Mass Inst of Technology
77 Massachusetts AvenueCambridgeMA021394301042103594501c3$74,250$0Research
Brigham & Women's Hospital
75 Francis StreetBostonMA02115042312909501c3$100,000$0Research
Mayo Clinic
200 First St SWRochesterMN55902416011702501c3$100,000$0Research
Baylor College of Medicine
1 Baylor PlazaHoustonTX77030741613878501c3$100,000$0Research
University of N Carolina
104 Airport DrChapel HillNC27599566001393501c3$25,000$0Research
American Thoracic Society
25 Broadway 18th FloorNew YorkNY10004202138855501c3$20,000$0Research
Nat Org Rare Disorders
55 Kenosia AvenueDanburyCT06810133223946501c3$25,000$0Patient support
FieldValueIRS element (for citing)
Total501c3 Org16Total501c3OrgCnt
Total Other Org0TotalOtherOrgCnt

Grants Other Asst To Indiv In US GrantsOtherAsstToIndivInUSGrp

FieldValueIRS element (for citing)
Grant TypeEducational scholarshipsGrantTypeTxt
Recipient22RecipientCnt
Cash Grant$53,500CashGrantAmt

Supplemental Information Detail SupplementalInformationDetail (9 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Part I Line 2The Foundation has a Grants Advisory Committee consisting of 22 members
Part I Line 2and 2 staff members assigned to the committee The membership of the
Part I Line 2committee consists of medical doctors who are Alpha1 experts and
Part I Line 2researchers The committee reviews grant applications for quality and
Part I Line 2applicability of research funds Prior to acceptance the prospective
Part I Line 2grantee is checked against the US Treasurys OFAC list On a quarterly
Part I Line 2basis all grants are peerreviewed for progress before subsequent payments
Part I Line 2are made Final reseach reports are submitted and peerreviewed before
Part I Line 2final grant payments are made

Schedule J IRS990ScheduleJ

FieldValueIRS element (for citing)
Compensation CommitteeYes (X)CompensationCommitteeInd
Independent ConsultantYes (X)IndependentConsultantInd
Form990 Of Other OrganizationsYes (X)Form990OfOtherOrganizationsInd
Written Employment ContractYes (X)WrittenEmploymentContractInd
Compensation SurveyYes (X)CompensationSurveyInd
Board Or Committee ApprovalYes (X)BoardOrCommitteeApprovalInd
Severance PaymentfalseSeverancePaymentInd
Supplemental Nonqual Rtr PlanfalseSupplementalNonqualRtrPlanInd
Equity Based Comp ArrngmfalseEquityBasedCompArrngmInd
Comp Based On Revenue Of Flng OrgfalseCompBasedOnRevenueOfFlngOrgInd
Comp Bsd On Rev Related OrgsfalseCompBsdOnRevRelatedOrgsInd
Comp Bsd Net Earns Flng OrgfalseCompBsdNetEarnsFlngOrgInd
Comp Bsd Net Earns Rltd OrgsfalseCompBsdNetEarnsRltdOrgsInd
Any Non Fixed PaymentsfalseAnyNonFixedPaymentsInd
Initial Contract ExceptionfalseInitialContractExceptionInd

Rltd Org Officer Trst Key Empl RltdOrgOfficerTrstKeyEmplGrp (17 entries)

TitleTitleTxtBase Compensation Filing OrgBaseCompensationFilingOrgAmtDeferred Compensation Flng OrgDeferredCompensationFlngOrgAmtTotal Compensation Filing OrgTotalCompensationFilingOrgAmt
SCOTT T SANTARELLA
President and CEO$76,853$491$77,344
RANDEL H PLANT
Sen Dir Research Progs$129,239$11,915$141,154
ANGELA T MCBRIDE
Sen Dir Corp Relations$115,193$15,483$130,676
MIRIAM A O'DAY
President and CEO$187,865$3,695$191,560
LINDA M RODRIGUEZ
Senior Dir Development$104,627$2,578$107,205
JEANINE D'ARMIENTO
Immediate Past Chair
ELIZABETH JOHNSON
Director
FRED C WALSH
Vice Chair
JON HAGSTROM
Chair
KENNETH IRVINE
Treasurer
PEGGY IVERSON
Director
ANN KNEBEL
Secretary
NOEL G MCELVANEY
Director
FARON SCHONFELD
Director
JAMES K STOLLER
Director
CATHERINE VERNON
Director
MARK B DELVAUX
CFO

Supplemental Information Detail SupplementalInformationDetail (4 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Part IIAlphaNet, Inc., another Section 501(c)(3) organization, provided the fiscal
Part II2022 services of the CFO under an administrative services agreement in the
Part IIamount of $100,000. The amount is based on a reasonable estimate of the
Part IIservices provided to the Alpha-1 Foundation.

Schedule M IRS990ScheduleM

Securities Publicly Traded SecuritiesPubliclyTradedGrp

FieldValueIRS element (for citing)
Non Cash CheckboxYes (X)NonCashCheckboxInd
Contribution3ContributionCnt
Noncash Contributions Rpt F990$8,894NoncashContributionsRptF990Amt
Method Of Determining RevenuesFMVMethodOfDeterminingRevenuesTxt

Other Non Cash Contri Table OtherNonCashContriTableGrp

FieldValueIRS element (for citing)
Non Cash CheckboxYes (X)NonCashCheckboxInd
DescOffice rentDesc
Contribution1ContributionCnt
Noncash Contributions Rpt F990$207,500NoncashContributionsRptF990Amt
Method Of Determining RevenuesFMVMethodOfDeterminingRevenuesTxt
FieldValueIRS element (for citing)
Any Property That Must Be HeldfalseAnyPropertyThatMustBeHeldInd
Review Process Unusual NC GiftsYes (true)ReviewProcessUnusualNCGiftsInd
Third Parties UsedfalseThirdPartiesUsedInd

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (37 entries)

Form And Line ReferenceFormAndLineReferenceDescExplanationExplanationTxt
Part III Line 2The Foundation launched a therapeutic development network, classified
Part III Line 2under the Alpha-1 Research Network.
Part VI Line 11bThe Form 990 is provided to members of management and the Board of
Part VI Line 11bDirectors for review prior to filing.
Part VI Line 12cWritten conflict of interest statements are obtained from all officers,
Part VI Line 12cboard members, and committee members on an annual basis.
Part VI Line 15a or bCompensation levels are developed using salary surveys and a review of 990s
Part VI Line 15a or bfor comparable not-for-profit organizations.
Part VI Line 18Form 990 is available on www.alpha1.org, and also upon request.
Part VI Line 19Audited financial statements are available on www.alpha1.org. Governing
Part VI Line 19documents and the conflict of interest policy are available upon request.
Part XI Line 9This amount refers to an audit adjustment made to reflect the value of
Part XI Line 9Alpha-1 Foundation's wholly owned subsidiary, The Alpha-1 Project.
Part III Line 4dExpenses: $160882.00 including grants of: $0.00 Revenue: $130000.00
Part III Line 4dThe mission of Alpha-1 Global is to develop a collaborative global network
Part IIIof Alpha-1 patient leaders, physicians, and researchers.
Part III Line 4dExpenses: $268797.00 including grants of: $0.00 Revenue: $230000.00
Part III Line 4dThe Foundation's Public Policy program monitors relevant legislation and
Part III Line 4dregulatory issues and publicizes the Foundation's positions on such issues.
Part III Line 4dExpenses: $227140.00 including grants of: $0.00 Revenue: $366000.00
Part III Line 4dThe Alpha-1-To-One Magazine is designed to inform the community of research
Part III Line 4ddevelopments, education, advocacy and fund raising opportunities.
Part III Line 4dExpenses: $164608.00 including grants of: $0.00 Revenue: $390000.00
Part III Line 4dAlpha-1 Education Days provide access to current medical information and
Part III Line 4dresources to hundreds of Alphas, their families, and caregivers.
Part III Line 4dExpenses: $561694.00 including grants of: $78500.00 Revenue: $333500.00
Part III Line 4dOther Alpha-1 services include patient education (materials, website, etc),
Part III Line 4da Patient Support Network, and a targeted detection program.
Part VI, Line 17The Alpha-1 Foundation is registered to accept charitable donations in all
Part VI, Line 17states that require it.
Part VII, Line 1aThe Chief Financial Officer is an employee of AlphaNet, Inc., an unrelated
Part VII, Line 1anot-for-profit organization which provides its services through an
Part VII, Line 1aadministrative services agreement.
Part VII, Line 5AlphaNet, Inc., another 501(c)(3) organization, provides the services of
Part VII, Line 5the Chief Financial Officer under an administrative services agreement in
Part VII, Line 5the amount of $100,000. The amount is based on the reasonable estimate of
Part VII, Line 5the value of the services provided to the Alpha-1 Foundation.

Schedule R IRS990ScheduleR

Id Related Org Txbl Corp Tr IdRelatedOrgTxblCorpTrGrp

Related Organization Name RelatedOrganizationName

FieldValueIRS element (for citing)
Business Name Line1The Alpha-1 ProjectBusinessNameLine1Txt

US Address USAddress

FieldValueIRS element (for citing)
Address Line13300 Ponce de Leon BoulevardAddressLine1Txt
CityCoral GablesCityNm
State AbbreviationFLStateAbbreviationCd
ZIP33134ZIPCd
FieldValueIRS element (for citing)
EIN272040293EIN
Primary ActivitiesDrug therapiesPrimaryActivitiesTxt
Legal Domicile StateDELegalDomicileStateCd
Direct Controlling NAN/ADirectControllingNACd
Entity TypeC CorpEntityTypeTxt
Share Of Total Income$226,954ShareOfTotalIncomeAmt
Share Of EOY Assets$363,826ShareOfEOYAssetsAmt
Ownership1.00000OwnershipPct
Controlled OrganizationYes (true)ControlledOrganizationInd
FieldValueIRS element (for citing)
Receipt Of Int Annts Rnts RyltsfalseReceiptOfIntAnntsRntsRyltsInd
Gift Grnt Or Cap Contri To Oth OrgfalseGiftGrntOrCapContriToOthOrgInd
Gift Grnt Cap Contri From Oth OrgfalseGiftGrntCapContriFromOthOrgInd
Loans Or Guarantees To Other OrgfalseLoansOrGuaranteesToOtherOrgInd
Loans Or Guarantees From Oth OrgfalseLoansOrGuaranteesFromOthOrgInd
Div Related OrganizationfalseDivRelatedOrganizationInd
Asset Sale To Other OrgfalseAssetSaleToOtherOrgInd
Asset Purchase From Other OrgfalseAssetPurchaseFromOtherOrgInd
Asset ExchangefalseAssetExchangeInd
Rental Of Facilities To Oth OrgfalseRentalOfFacilitiesToOthOrgInd
Rental Of Fclts From Oth OrgfalseRentalOfFcltsFromOthOrgInd
Perform Of Services For Oth OrgfalsePerformOfServicesForOthOrgInd
Perform Of Services By Other OrgfalsePerformOfServicesByOtherOrgInd
Sharing Of FacilitiesfalseSharingOfFacilitiesInd
Paid Employees SharingfalsePaidEmployeesSharingInd
Reimbursement Paid To Other OrgfalseReimbursementPaidToOtherOrgInd
Reimbursement Paid By Other OrgYes (true)ReimbursementPaidByOtherOrgInd
Transfer To Other OrgfalseTransferToOtherOrgInd
Transfer From Other OrgfalseTransferFromOtherOrgInd

Transactions Related Org TransactionsRelatedOrgGrp

Other Organization Name OtherOrganizationName

FieldValueIRS element (for citing)
Business Name Line1The Alpha-1 ProjectBusinessNameLine1Txt
FieldValueIRS element (for citing)
Transaction TypeQTransactionTypeTxt
Involved$9,775InvolvedAmt
Method Of Amount DeterminationManagement approvalMethodOfAmountDeterminationTxt

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