J CRAIG VENTER INSTITUTE INC: Form 990, tax year 2023

View the entire original 990 at ProPublica ↗

Organization: J CRAIG VENTER INSTITUTE INC (EIN 52-1842938)
Tax period: 2023-01-01 to 2023-12-31
Filed: 2024-11-05
IRS object ID: 202443109349303919
Schema version: 2023v5.1
Source: Download XML · Original 990 at ProPublica

Every field in the e-filed return. Faint text is the IRS element name, for citing.

Return header
Form 990
Schedule A
Schedule B
Schedule D
Schedule F
Schedule I
Schedule J
Schedule O

Return header ReturnHeader

Field	Value	IRS element (for citing)
Return	2024-11-05T17:38:05-06:00	ReturnTs
Tax Period End	2023-12-31	TaxPeriodEndDt

Preparer Firm PreparerFirmGrp

Field	Value	IRS element (for citing)
Preparer Firm EIN	910189318	PreparerFirmEIN

Preparer Firm Name PreparerFirmName

Field	Value	IRS element (for citing)
Business Name Line1	MOSS ADAMS LLP	BusinessNameLine1Txt

Preparer US Address PreparerUSAddress

Field	Value	IRS element (for citing)
Address Line1	4747 EXECUTIVE DR SUITE 1300	AddressLine1Txt
City	SAN DIEGO	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92121	ZIPCd

Field	Value	IRS element (for citing)
Return Type	990	ReturnTypeCd
Tax Period Begin	2023-01-01	TaxPeriodBeginDt

Filer Filer

Field	Value	IRS element (for citing)
EIN	521842938	EIN

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	J CRAIG VENTER INSTITUTE	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Business Name Control	JCRA	BusinessNameControlTxt
Phone	8582001800	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	4120 CAPRICORN LANE	AddressLine1Txt
City	LA JOLLA	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92037	ZIPCd

Business Officer BusinessOfficerGrp

Field	Value	IRS element (for citing)
Person	JOHN CRAIG VENTER	PersonNm
Person Title	CHAIRMAN AND CEO	PersonTitleTxt
Phone	8582001800	PhoneNum
Signature	2024-11-05	SignatureDt
Discuss With Paid Preparer	Yes (1)	DiscussWithPaidPreparerInd

Field	Value	IRS element (for citing)
IRS Responsible Prty Info Curr	0	IRSResponsiblePrtyInfoCurrInd

Preparer Person PreparerPersonGrp

Field	Value	IRS element (for citing)
Preparer Person	PATRICIA J MAYER	PreparerPersonNm
PTIN	P00188643	PTIN
Phone	8586271400	PhoneNum

Field	Value	IRS element (for citing)
Tax	2023	TaxYr
Build TS	2024-10-15 13:58:12Z	BuildTS

Form 990 IRS990

Field	Value	IRS element (for citing)
Principal Officer	JOHN CRAIG VENTER	PrincipalOfficerNm

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	4120 CAPRICORN LANE	AddressLine1Txt
City	LA JOLLA	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92037	ZIPCd

Field	Value	IRS element (for citing)
Gross Receipts	$20,423,227	GrossReceiptsAmt
Group Return For Affiliates	0	GroupReturnForAffiliatesInd
Organization501c3	Yes (X)	Organization501c3Ind
Website Address	WWW.JCVI.ORG	WebsiteAddressTxt
Type Of Organization Corp	Yes (X)	TypeOfOrganizationCorpInd
Formation	1993	FormationYr
Legal Domicile State	MD	LegalDomicileStateCd
Activity Or Mission	JCVI IS ADVANCING THE SCIENCE OF GENOMICS THROUGH BOLD INNOVATIONS. OUR MISSION IS TO UNDERSTAND MORE ABOUT THE BIOLOGICAL WORLD, AND TO DEVELOP UNIQUE INSIGHTS AND ANSWERS ABOUT DISEASE, HEALTH, AND THE ENVIRONMENT FOR THE BENEFIT OF ALL.	ActivityOrMissionDesc
Voting Members Governing Body	9	VotingMembersGoverningBodyCnt
Voting Members Independent	7	VotingMembersIndependentCnt
Total Employee	134	TotalEmployeeCnt
Total Volunteers	7	TotalVolunteersCnt
Total Gross UBI	$9,582	TotalGrossUBIAmt
Net Unrelated Bus Txbl Incm	$5,836	NetUnrelatedBusTxblIncmAmt
PY Contributions Grants	$16,500,408	PYContributionsGrantsAmt
CY Contributions Grants	$15,104,824	CYContributionsGrantsAmt
PY Program Service Revenue	$0	PYProgramServiceRevenueAmt
CY Program Service Revenue	$0	CYProgramServiceRevenueAmt
PY Investment Income	-$15,395,627	PYInvestmentIncomeAmt
CY Investment Income	$18,333	CYInvestmentIncomeAmt
PY Other Revenue	$27,731	PYOtherRevenueAmt
CY Other Revenue	$9,582	CYOtherRevenueAmt
PY Total Revenue	$1,132,512	PYTotalRevenueAmt
CY Total Revenue	$15,132,739	CYTotalRevenueAmt
PY Grants And Similar Paid	$2,934,839	PYGrantsAndSimilarPaidAmt
CY Grants And Similar Paid	$2,483,399	CYGrantsAndSimilarPaidAmt
PY Benefits Paid To Members	$0	PYBenefitsPaidToMembersAmt
CY Benefits Paid To Members	$0	CYBenefitsPaidToMembersAmt
PY Salaries Comp Emp Bnft Paid	$14,376,767	PYSalariesCompEmpBnftPaidAmt
CY Salaries Comp Emp Bnft Paid	$13,562,992	CYSalariesCompEmpBnftPaidAmt
PY Total Prof Fndrsng Expns	$0	PYTotalProfFndrsngExpnsAmt
CY Total Prof Fndrsng Expns	$0	CYTotalProfFndrsngExpnsAmt
CY Total Fundraising Expense	$428,398	CYTotalFundraisingExpenseAmt
PY Other Expenses	$6,002,601	PYOtherExpensesAmt
CY Other Expenses	$5,799,283	CYOtherExpensesAmt
PY Total Expenses	$23,314,207	PYTotalExpensesAmt
CY Total Expenses	$21,845,674	CYTotalExpensesAmt
PY Revenues Less Expenses	-$22,181,695	PYRevenuesLessExpensesAmt
CY Revenues Less Expenses	-$6,712,935	CYRevenuesLessExpensesAmt
Total Assets BOY	$56,307,767	TotalAssetsBOYAmt
Total Assets EOY	$48,982,028	TotalAssetsEOYAmt
Total Liabilities BOY	$9,402,615	TotalLiabilitiesBOYAmt
Total Liabilities EOY	$10,026,647	TotalLiabilitiesEOYAmt
Net Assets Or Fund Balances BOY	$46,905,152	NetAssetsOrFundBalancesBOYAmt
Net Assets Or Fund Balances EOY	$38,955,381	NetAssetsOrFundBalancesEOYAmt
Info In Schedule O Part III	Yes (X)	InfoInScheduleOPartIIIInd
Mission	J. CRAIG VENTER INSTITUTE (JCVI) IS AN INDEPENDENT 501(C)(3) NONPROFIT ORGANIZATION ADVANCING THE SCIENCE OF GENOMICS COMMITTED TO ACCELERATING FOUNDATIONAL SCIENTIFIC RESEARCH TO DRIVE ADVANCES IN HUMAN HEALTH AND ENVIRONMENTAL SUSTAINABILITY. THIS PAST YEAR JCVI COMMITTED RESEARCH EFFORTS IN HUMAN HEALTH, ENVIRONMENTAL SUSTAINABILITY, SYNTHETIC BIOLOGY, AND SOFTWARE TOOLS AND TECHNOLOGY.	MissionDesc
Significant New Program Srvc	0	SignificantNewProgramSrvcInd
Significant Change	0	SignificantChangeInd
Expense	$8,738,224	ExpenseAmt
Grant	$2,412,163	GrantAmt
Revenue	$0	RevenueAmt
Desc	DEPARTMENT OF HEALTH AND HUMAN SERVICES: TWO MILLION PEOPLE IN THE U.S. ARE DIAGNOSED ANNUALLY WITH LIFE-THREATENING INFECTIONS CAUSED BY ANTIBIOTIC RESISTANT BACTERIA THAT ARE RESPONSIBLE FOR 35,000 DEATHS EACH YEAR WITH AN ECONOMIC IMPACT ESTIMATED TO BE AS MUCH AS $20 BILLION A YEAR IN DIRECT HEALTHCARE COSTS. DUE TO THE SPREAD OF ANTIBIOTIC RESISTANCE, VERY FEW DRUGS REMAIN THAT CAN TREAT THESE INFECTIONS. LED BY DERRICK FOUTS, PHD, (JCVI) AND FUNDED BY THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC), THE J. CRAIG VENTER INSTITUTE AND CLEVELAND VA PREVENTION AND INTERVENTION EPICENTER ARE DEVELOPING NOVEL INTERVENTIONS THAT WILL PREVENT THE COLONIZATION AND SPREAD OF ANTIBIOTIC RESISTANT (AR) BACTERIA THAT CAUSE HOSPITAL ACQUIRED INFECTIONS (HAI), AND TO DEVELOP DIAGNOSTICS AND INTERVENTIONS TO COMBAT THE COLONIZATION BY THE RAPIDLY EMERGING FUNGAL PATHOGEN CANDIDA AURIS. RICHARD SCHEUERMANN, PHD, IS LEADING A TEAM OF INVESTIGATORS AT JCVI IN RESPONSE TO THE COVID-19 OUTBREAK. THROUGH HIS NIH-SPONSORED BIOINFORMATICS RESOURCE CENTER PROJECT, HIS TEAM RELEASED A DEDICATED PUBLIC WEB PORTAL FOR THE SARS-COV-2 VIRUS DURING THE EARLY STAGES OF THE OUTBREAK TO ENSURE DATA AND TOOLS ARE ACCESSIBLE TO FRONTLINE RESEARCHERS WORLDWIDE. ADDITIONALLY, IN COLLABORATION WITH INVESTIGATORS FROM LA JOLLA INSTITUTE FOR IMMUNOLOGY, DR. SCHEUERMANN AND HIS TEAM PROVIDED MACHINE LEARNING METHODS TO HELP COMPLETE THE FIRST ANALYSIS THAT IDENTIFIED POTENTIAL TARGETS FOR HUMAN IMMUNE RESPONSES TO SARS-COV-2 INFECTION. THIS INFORMATION IS CRUCIAL TO THE DESIGN AND EVALUATION OF DIAGNOSTICS AND VACCINE CANDIDATES.	Desc

Prog Srvc Accom Acty2 ProgSrvcAccomActy2Grp

Field	Value	IRS element (for citing)
Expense	$799,972	ExpenseAmt
Grant	$0	GrantAmt
Revenue	$0	RevenueAmt
Desc	DEPARTMENT OF ENERGY: JCVI IS THE RECIPIENT OF A LARGE COLLABORATIVE ASSISTANCE AWARD FROM THE US DEPARTMENT OF ENERGY. AWARDED TO THE VALUE OF $10.7M. LED BY ANDREW ALLEN, PHD, THE JCVI AND ITS COLLABORATORS, COLORADO STATE UNIVERSITY, VANDERBILT UNIVERSITY AND THE UNIVERSITY OF CALIFORNIA, SAN DIEGO, SEEK TO LEVERAGE SIGNIFICANT RECENT ADVANCES IN DIATOM GENOME ENGINEERING AND METABOLIC MODELING; INCLUDING THE ABILITY TO INTRODUCE CHROMOSOME-LIKE EXPRESSION PLATFORMS, WHICH SUBSTANTIALLY ADVANCE POSSIBILITIES FOR HIGH-THROUGHPUT GENERATION AND SCREENING OF GENETICALLY ENGINEERED DIATOMS. RESEARCH PROPOSED HERE WILL RESULT IN DRAMATIC IMPROVEMENTS IN THE PREDICATIVE CAPACITY OF EXISTING GENOME SCALE METABOLIC MODELS OF DIATOM METABOLISM. FOR THE FIRST TIME ON A LARGE SCALE, FLUXOMICS, WHICH IS COMPOUND SPECIFIC INCORPORATION OF AN ISOTOPICALLY-LABELED FEEDSTOCK, WILL BE USED TO PROVIDE BETTER FIRST STEP CONSTRAINTS ON CO2 ASSIMILATION OF IN DIATOMS. STATE-OF-THE-ART HIGH THROUGHPUT IN VITRO EXAMINATIONS OF NEARLY ALL 200 DIATOM TRANSCRIPTION FACTORS WILL BE CONDUCTED TO BETTER UNDERSTAND REGULATORY ARCHITECTURE UNDERLYING DIATOM METABOLISM AS WELL AS SERVE AS A SOURCE FOR NEW TOOLS FOR GENOME ENGINEERING. TAKEN TOGETHER, RESEARCH PROPOSED HERE WILL ADDRESS CURRENTLY LIMITING BOTTLENECKS THROUGH FOSTERING STATE-OF-THE-ART INTEGRATION OF GENOME-SCALE MODELING WITH GENOME ENGINEERING TO OPTIMIZE ENERGY AND METABOLTE FLUX THROUGH SUBCELLULAR COMPARTMENTS TO PROMOTE EFFICIENT PRODUCTION OF HIGH VALUE AND FUEL-RELATED METABOLITES.	Desc

Prog Srvc Accom Acty3 ProgSrvcAccomActy3Grp

Field	Value	IRS element (for citing)
Expense	$1,692,603	ExpenseAmt
Grant	$71,236	GrantAmt
Revenue	$0	RevenueAmt
Desc	NATIONAL SCIENCE FOUNDATION CONTINUES TO FUND THE J. CRAIG VENTER INSTITUTE (JCVI) IN THE AREAS OF SYNTHETIC BIOLOGY AND INTEGRATIVE ORGANISMAL SYSTEMS CORE PROGRAMS. UNDER THE DIVISION OF MOLECULAR AND CELLULAR BIOSCIENCE AND IN COLLABORATION WITH THE UNIVERSITY OF ILLINOIS MINIMAL BACTERIAL CELL COMPUTATIONAL MODELING TEAM, LED BY XZAN LUTEHY-SCHULTEN, JCVI RESEARCHERS LED BY DR. JOHN GLASS, ARE CARRYING OUT TRANSCRIPTOME AND METABOLOMIC ANALYSES, BIOCHEMICAL AND GENETIC EXPERIEMENTS TO DISCOVER UNKNOWN GENE FUNCTIONS, OPTIMIZATION OF A MINIMAL CELL DEFINED GROWTH MEDIUM, AND CONSTRCUTION OF MINIMAL CELL MUTANTS TO FACILITATE THE WORK OF JCVI AND OTHER GROUPS INVESTIGATING MINIMAL CELL BIOLOGY. THIS IS A MULTI-YEAR STUDY WITH COLLABORATIVE FUNDING OF $2 MILLION.LED BY DR. ANDREW ALLEN AND IN COLLABORATION WITH THE UNIVERSITY OF CALIFORNIA SAN DIEGO (UCSD), JCVI AND UCSD BRING TOGETHER COLLECTIVE EXPERIENCE WITH DIATOM MOLECULAR GENETICS, CURRENT DIATOM MODEL ORGANISMS, MARINE BIOCHEMISTRY AND MICROSCOPY AND OUR RECENT DISCOVERY AND CHARACTERIZATION OF THE HITHERTO UNKNOWN PATHWAY FOR DA BIOSYNTHESIS, TO ESTABLISH PSEUDO-NITZSCHIA SP., AS NEW MODEL DIATOM. IN SO DOING, MOLECULAR BIOLOGICAL METHODS WILL BE DEVELOPED TO ENABLE GENOME-TO-PHENOME INVESTIGATIONS OF THE REGULATION AND BIOSYNTHESIS OF DA. SPECIFICALLY, A METHOD TO TRANSFORM PSEUDO-NITZSCHIA SP DRIVEN BY BACTERIAL CONJUGATION WILL BE DEVELOPED AND DISSEMINATED TO MARINE LABS WORLDWIDE. THE HARMFUL ALGAL BLOOMS (HABS) THREATENING ECOSYSTEMS, FISHERIES AND HUMAN HEALTH WORLDWIDE, ARE DRIVEN BY ONE DIATOM GENUS, PSEUDO-NITZSCHIA, ALONG WITH SEVERAL DINOFLAGELLATE GENERA AND CYANOBACTERIA. IN THE LAST DECADE, VARIOUS SPECIES OF PSEUDO-NITZSCHIA HAVE PRODUCED DEVASTING BLOOMS OF THE NEUROTOXIN, DOMOIC ACID (DA), IN THE COASTAL WATERS OF AUSTRALIA, BRAZIL, CALIFORNIA, CHILE, FRANCE, THE GULF OF MAINE, INDONESIA, ITALY, AND TUNISIA. CURRENTLY, THERE IS GREAT UNCERTAINTY REGARDING HOW OCEAN ACIDIFICATION, INCREASED CONCENTRATIONS OF ATMOSPHERIC CO2, PRECIPITATION, AND NUTRIENT STRESS WILL SHAPE THE PRODUCTIVITY AND GLOBAL RANGE OF PSEUDO-NITZSCHIA SPECIES. INDEED, LONG TERM TRENDS HAVE EMERGED THAT LINK TOXIC PSEUDO-NITZSCHIA SPP. BLOOMS TO MORE FREQUENT DA CONTAMINATION OF SHELLFISH FISHERIES IN THE WARMER OCEAN TEMPERATURES THAT PREVAIL DURING WARMER YEARS. THIS IS A MULTI-YEAR STUDY WITH COLLABORATIVE FUNDING OF $1.6 MILLION.LED BY DR. JOHN GLASS, THE JCVI IS INVESTIGATING THE MECHANISM OF GENOME TRANSPLANTATION, DEVELOPING GENOME TRANSPLANTATION FOR AT LEAST TWO SPECIES OF NON-MYCOPLASMA BACTERIA, AND USING MICROFLUIDICS TECHNOLOGY TO AUTOMATE AND IMPROVE THE EFFICIENCY OF GENOME TRANSPLANTATION. GENOME TRANSPLANTATION, THE INSERTION OF A COMPLETE BACTERIAL GENOME INTO A SUITABLE RECIPIENT CELL SO THAT THE DONATED GENOME COMMANDEERS THE RECIPIENT CELL TO PRODUCE A NEW CELL WITH THE GENOTYPE AND PHENOTYPE OF THE DONATED GENOME, WAS THE FUNDAMENTAL TECHNICAL DEVELOPMENT THAT ENABLED THE CONSTRUCTION OF THE FIRST BACTERIUM WITH A SYNTHETIC GENOME. AT THE ANNOUNCEMENT OF THE CREATION OF THE WORLD'S FIRST SYNTHETIC CELL, JCVI-SYN1.0, THE WORK WAS HERALDED AS A MAJOR ACCOMPLISHMENT FOR MANKIND. TO DATE, GENOME TRANSPLANTATION HAS ONLY BEEN ACHIEVED USING A SMALL SUBSET OF THE ATYPICAL BACTERIA CALLED MYCOPLASMAS. THIS IS A MULTI-YEAR STUDY WITH COLLABORATIVE FUNDING OF $1 MILLION.	Desc

Prog Srvc Accom Acty Other ProgSrvcAccomActyOtherGrp

Field	Value	IRS element (for citing)
Expense	$38,090	ExpenseAmt
Grant	$0	GrantAmt
Revenue	$0	RevenueAmt
Desc	OTHER: AS PART OF THEIR INAUGURAL GRANT CYCLE, THE CONRAD PREBYS FOUNDATION FUNDED THE INSTITUTES RESEARCH WORK IN BOTH CORONARY ARTERY DISEASE AND SARS-COV-2. HEART DISEASE IS THE LEADING CAUSE OF DEATH IN THE US AND CORONARY ARTERY DISEASE (CAD) IS THE MOST COMMON TYPE OF HEART DISEASE, KILLING ~366,000 PEOPLE ANNUALLY IN THE US. ABOUT 6.7% (18.2 MILLION) US ADULTS HAVE CAD AND ~20% OF DEATHS FROM CAD OCCUR BEFORE AGE 65. A LIST OF GENETIC FACTORS LINKED TO CAD HAS BEEN FOUND OVER THE LAST FEW DECADES. BUT THEY ONLY EXPLAIN A SMALL PORTION OF THE HERITABILITY IN CAD. TO BETTER UNDERSTAND THE GENETICS AND ETIOLOGY OF CAD AT GENOMIC LEVEL, MORE RARE GENETIC VARIANTS NEED TO BE INVESTIGATED. LED BY WEIZHONG LI, THIS PROJECT, ANALYZED THE WHOLE GENOME DEEP SEQUENCE DATA OF A LARGE COHORT OF ~1000 CAD PATIENTS. USING THE CLOUD-BASED GENOME ANALYSIS PIPELINE, HUNDREDS OF TERABYTES OF SEQUENCE DATA WERE PROCESSED AND MILLIONS OF VARIOUS TYPES OF GENETIC VARIANTS WERE IDENTIFIED. A LIST OF VARIANTS ARE FOUND TO BE ASSOCIATED WITH CAD AND THE EXTENT OF DISEASE IN CAD. BY USING MACHINE LEARNING APPROACHES, WE BUILT VERY ACCURATE PREDICTIVE MODELS FOR THE PREDICTION OF CAD RISKS AND DISEASE SEVERITY. EARLY WARNING SYSTEM FOR SARS-COV-2 IMMUNE ESCAPE PROJECT. NEUTRALIZING ANTIBODIES ELICITED AGAINST THE SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS (SARS-COV-2) SPIKE PROTEIN IS WIDELY ACCEPTED AS THE MAIN CORRELATE OF PROTECTION. TO BETTER UNDERSTAND THE ROLE OF ANTIBODIES IN NEUTRALIZATION AND PROTECTION, JCVI, LED BY RICHARD SCHEUERMANN, PHD, AND GENE TAN, PHD, IS CONSTRUCTING A PANEL OF CHIMERIC PSEUDOVIRUSES (BASED ON THE VESICULAR STOMATITIS VIRUS PLATFORM) THAT WE HYPOTHESIZE CAN REVEAL THE IMMUNOLOGICAL DOMINANT AND SUBDOMINANT ANTIGENIC REGIONS OF THE SPIKE PROTEIN. NOTABLY, OUR APPROACH CAN IDENTIFY SUBDOMINANT REGIONS WITHIN THE SPIKE THAT ARE HIGHLY CONSERVED EVEN AMONGST SARS-COV-2 VARIANTS OF CONCERN (VOCS). COVID19 CONTINUES TO IMPACT GLOBAL HEALTH, HIGHLIGHTING THE NEED TO DEVELOP NOVEL THERAPEUTICS. MARCELO FREIRE, PHD, AND HIS LABORATORY DISCOVERED THAT SALIVA IS A BIOFLUID IMPORTANT FOR MEASURING THE VIRUS BUT ALSO THE IMMUNE RESPONSE PRESENTING DIVERSE IMMUNE CELL POPULATIONS. WHITIN SALIVA, WE FIND VARIOUS ANTIVIRAL, ANTI-INFLAMMATORY AND ANTI-BACTERIAL FUNCTIONS. DIFFERENT FROM BLOOD, SALIVARY IMMUNE CELLS ARE IN DIRECT CONTACT WITH THE LIVE VIRUS. IN THIS PROPOSAL WE INVESTIGATED (I) THE COMPOSITION OF ANTIVIRAL IMMUNE CELLS, (II) THE PROTEIN SEQUENCE OF ANTIVIRAL MOLECULES DERIVED FROM INNATE IMMUNE CELLS, AND (III) THEIR MECHANISM OF ACTION. THE FREIRE LAB HAVE SUCCESSFULLY COLLECTED SAMPLES FROM COVID-19 AND HEALTHY CONTROL SAMPLES AND INITIATED SEQUENCING OF SALIVA CELLS IN HEALTH AND IN COVID-19. IN ADDITION, WE ALSO RECRUITED SAMPLES LONGITUDINALLY AT JCVI TO EVALUATE HEALTHY VERSUS DISEASE. TO DATE, WE COMPLETED IMMUNOGLOBULIN IMMUNOASSAYS OF ALL OUR SAMPLES INCLUDING INVESTIGATIONS TO CUSTOM ELISA ASSAYS FOR SARS-COV-2 ANTIGENS (RBD, S1, S2, NP PROTEINS). WE HAVE IDENTIFIED THAT SALIVARY IMMUNOGLOBULIN IGA AS HIGHLY SIGNIFICANT COMPARED TO BLOOD PLASMA LEVELS. SEVERAL MARKERS FROM IGG AND IGA RESPONSES WERE FOUND IN SALIVA AS WELL AS PLASMA. SIMPLE LINEAR REGRESSION MODEL VERIFIED SIGNIFICANT CORRELATIONS BETWEEN SALIVA AND PLASMA ANTIBODY RESPONSES, SPECIFICALLY FOR THE IGA (P=0.001), IGG (P=0.037), AND IGM (P=0.0054) SPECIFIC TO THE SARS-COV-2 RECEPTOR BINDING SITE (RBD). THESE ARE ANTIVIRAL MOLECULES THAT HAVE POTENTIAL TO BLOCK VIRAL ACTIVITY. TO TEST THIS FURTHER FROM OUR ASSAYS, JCVI PERFORMED A NEUTRALIZATION ASSAY AND COMPARATIVE ANALYSIS TO UNDERSTAND IF THESE MOLECULES HAVE A FUNCTIONAL RESPONSE. DESPITE THAT SALIVA CONTAINED ROBUST IGA RESPONSE TO THE SARS-COV-2, WHICH WAS EVEN HIGHER THAN PLASMA, MOST OF SALIVA SAMPLES DEMONSTRATED LEVEL OF NEUTRALIZATION OF VESICULAR STOMATITIS VIRUS (VSV) PSEUDOVIRUSES BEARING S OF SARS-COV-2 (RVSV-GFPG*SPIKE). IT WAS CONTRASTED WITH THAT THE PLASMA DISPLAYED A SIGNIFICANT LEVEL OF NEUTRALIZING ACTIVITY EVEN FROM HEALTHY INDIVIDUALS. THESE RESULTS SUGGEST THAT THE ORAL MUCOSAL IMMUNE COMPONENTS COOPERATE WITH SYSTEMIC IMMUNE RESPONSE IN RESPONSE TO THE SARS-COV-2 INFECTION. SALIVA AND PLASMA SAMPLES CONTAINED SIGNIFICANTLY HIGHER LEVELS OF SARS-COV-2 SPECIFIC ANTIBODIES THAN HEALTHY AND WE DISCOVERED MULTIPLE PEPTIDES PRESENT A ROLE AGAINST VIRAL PARTICLES. ULTIMATELY, THIS PROJECT AIMS TO MAP THE SALIVARY MOLECULAR CONTENT WHEN EXPOSED TO THE VIRUS. WE AIM PROVIDE TO THE SCIENTIFIC COMMUNITY A NEW LAYER OF IMMUNE RESPONSE COMPOSITION AND FUNCTION RELATED TO MUCOSAL LINING WHEN FACING VIRAL ATTACK. THIS WILL THEN GUIDE NEW CLINICAL APPROACHES WITH THE FORMATION OF THE THERAPEUTICS THAT EMULATE HOW AND WHY THE MUCOSAL TISSUES KEEP DISEASE IN CHECK. SANJAY VASHEE, PHD, COLLABORATING WITH INVESTIGATORS AT THE UNIVERSITY OF MARYLAND TO USE SYNTHETIC GENOMICS TO DEVELOP A SARS-COV-2 INFECTIOUS CLONE. THEY ARE PAIRING THIS WITH A RAPID, MODULAR REVERSE GENETIC SYSTEM TO ASSESS GENOMIC VARIANTS IDENTIFIED IN THE WEALTH OF GLOBAL SEQUENCING DATA, DEVELOP AND TEST VACCINE CANDIDATES, AND GENERATE NEEDED REAGENTS, INCLUDING FLUORESCENT AND TAGGED VIRUS STRAINS. MARCELO FREIRE, PHD, IS LEADING EFFORTS IN THE DEVELOPMENT OF A SALIVARY SEROLOGICAL AND IMMUNE TESTING. MONITORING SALIVA IMMUNITY PROVIDES NON-INVASIVE MOLECULAR INFORMATION, ESSENTIAL FOR DIAGNOSTICS, AND RESPONSE TO THERAPY DURING THE PANDEMIC. HIS LABORATORY IS COMPARING COVID-19 PATIENTS' BLOOD AND SALIVARY IMMUNOGLOBULINS LEVELS TO FIND BETTER WAYS TO EVALUATE IMMUNE RESPONSE TO SARS-COV-2.	Desc

Field	Value	IRS element (for citing)
Total Other Prog Srvc Expense	$38,090	TotalOtherProgSrvcExpenseAmt
Total Other Prog Srvc Grant	$0	TotalOtherProgSrvcGrantAmt
Total Other Prog Srvc Revenue	$0	TotalOtherProgSrvcRevenueAmt
Total Program Service Expenses	$11,268,889	TotalProgramServiceExpensesAmt
Described In Section501c3	Yes (1)	DescribedInSection501c3Ind
Schedule B Required	Yes (1)	ScheduleBRequiredInd
Political Campaign Acty	0	PoliticalCampaignActyInd
Lobbying Activities	0	LobbyingActivitiesInd
Subject To Proxy Tax	0	SubjectToProxyTaxInd
Donor Advised Fund	0	DonorAdvisedFundInd
Conservation Easements	0	ConservationEasementsInd
Collections Of Art	Yes (1)	CollectionsOfArtInd
Credit Counseling	0	CreditCounselingInd
Donor Rstr Or Quasi Endowments	0	DonorRstrOrQuasiEndowmentsInd
Report Land Building Equipment	Yes (1)	ReportLandBuildingEquipmentInd
Report Investments Other Sec	0	ReportInvestmentsOtherSecInd
Report Program Related Invst	0	ReportProgramRelatedInvstInd
Report Other Assets	Yes (1)	ReportOtherAssetsInd
Report Other Liabilities	Yes (1)	ReportOtherLiabilitiesInd
Include FIN48 Footnote	Yes (1)	IncludeFIN48FootnoteInd
Independent Audit Fincl Stmt	Yes (1)	IndependentAuditFinclStmtInd
Consolidated Audit Fincl Stmt	0	ConsolidatedAuditFinclStmtInd
School Operating	0	SchoolOperatingInd
Foreign Office	0	ForeignOfficeInd
Foreign Activities	Yes (1)	ForeignActivitiesInd
More Than5000 K To Org	Yes (1)	MoreThan5000KToOrgInd
More Than5000 K To Individuals	0	MoreThan5000KToIndividualsInd
Professional Fundraising	0	ProfessionalFundraisingInd
Fundraising Activities	0	FundraisingActivitiesInd
Gaming Activities	0	GamingActivitiesInd
Operate Hospital	0	OperateHospitalInd
Grants To Organizations	Yes (1)	GrantsToOrganizationsInd
Grants To Individuals	0	GrantsToIndividualsInd
Schedule J Required	Yes (1)	ScheduleJRequiredInd
Tax Exempt Bonds	0	TaxExemptBondsInd
Engaged In Excess Benefit Trans	0	EngagedInExcessBenefitTransInd
PY Excess Benefit Trans	0	PYExcessBenefitTransInd
Loan Outstanding	0	LoanOutstandingInd
Grant To Related Person	0	GrantToRelatedPersonInd
Business Rln With Org Mem	0	BusinessRlnWithOrgMemInd
Business Rln With Fam Mem	0	BusinessRlnWithFamMemInd
Business Rln With35 Ctrl Ent	0	BusinessRlnWith35CtrlEntInd
Deductible Non Cash Contri	0	DeductibleNonCashContriInd
Deductible Art Contribution	0	DeductibleArtContributionInd
Terminate Operations	0	TerminateOperationsInd
Partial Liquidation	0	PartialLiquidationInd
Disregarded Entity	0	DisregardedEntityInd
Related Entity	0	RelatedEntityInd
Related Organization Ctrl Ent	0	RelatedOrganizationCtrlEntInd
Trnsfr Exmpt Non Chrtbl Rltd Org	0	TrnsfrExmptNonChrtblRltdOrgInd
Activities Conducted Prtshp	0	ActivitiesConductedPrtshpInd
Schedule O Required	Yes (1)	ScheduleORequiredInd
IRP Document	14	IRPDocumentCnt
IRP Document W2 G	0	IRPDocumentW2GCnt
Backup Wthld Compliance	Yes (1)	BackupWthldComplianceInd
Employee	134	EmployeeCnt
Employment Tax Returns Filed	Yes (1)	EmploymentTaxReturnsFiledInd
Unrelated Bus Incm Over Limit	Yes (1)	UnrelatedBusIncmOverLimitInd
Form990 T Filed	Yes (1)	Form990TFiledInd
Foreign Financial Account	0	ForeignFinancialAccountInd
Prohibited Tax Shelter Trans	0	ProhibitedTaxShelterTransInd
Taxable Party Notification	0	TaxablePartyNotificationInd
Nondeductible Contributions	0	NondeductibleContributionsInd
Quid Pro Quo Contributions	0	QuidProQuoContributionsInd
Form8282 Property Disposed Of	0	Form8282PropertyDisposedOfInd
Rcv Fnds To Pay Prsnl Bnft Cntrct	0	RcvFndsToPayPrsnlBnftCntrctInd
Pay Premiums Prsnl Bnft Cntrct	0	PayPremiumsPrsnlBnftCntrctInd
Indoor Tanning Services	0	IndoorTanningServicesInd
Subj To Tax Rmnrtn Ex Prcht Pymt	Yes (1)	SubjToTaxRmnrtnExPrchtPymtInd
Subject To Excs Tax Net Invst Inc	0	SubjectToExcsTaxNetInvstIncInd
Info In Schedule O Part VI	Yes (X)	InfoInScheduleOPartVIInd
Governing Body Voting Members	9	GoverningBodyVotingMembersCnt
Independent Voting Member	7	IndependentVotingMemberCnt
Family Or Business Rln	Yes (1)	FamilyOrBusinessRlnInd
Delegation Of Mgmt Duties	0	DelegationOfMgmtDutiesInd
Change To Org Documents	0	ChangeToOrgDocumentsInd
Material Diversion Or Misuse	0	MaterialDiversionOrMisuseInd
Members Or Stockholders	0	MembersOrStockholdersInd
Election Of Board Members	0	ElectionOfBoardMembersInd
Decisions Subject To Approva	0	DecisionsSubjectToApprovaInd
Minutes Of Governing Body	Yes (1)	MinutesOfGoverningBodyInd
Minutes Of Committees	Yes (1)	MinutesOfCommitteesInd
Officer Mailing Address	0	OfficerMailingAddressInd
Local Chapters	0	LocalChaptersInd
Form990 Provided To Gvrn Body	Yes (1)	Form990ProvidedToGvrnBodyInd
Conflict Of Interest Policy	Yes (1)	ConflictOfInterestPolicyInd
Annual Disclosure Covered Prsn	Yes (1)	AnnualDisclosureCoveredPrsnInd
Regular Monitoring Enfrc	Yes (1)	RegularMonitoringEnfrcInd
Whistleblower Policy	Yes (1)	WhistleblowerPolicyInd
Document Retention Policy	Yes (1)	DocumentRetentionPolicyInd
Compensation Process CEO	Yes (1)	CompensationProcessCEOInd
Compensation Process Other	Yes (1)	CompensationProcessOtherInd
Investment In Joint Venture	0	InvestmentInJointVentureInd
States Where Copy Of Return Is Fld	AL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	AR	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	CA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	FL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	GA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	HI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	IL	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	KS	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	KY	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MA	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MD	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MI	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MN	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	MS	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NC	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	ND	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NH	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	NJ	StatesWhereCopyOfReturnIsFldCd
States Where Copy Of Return Is Fld	VA	StatesWhereCopyOfReturnIsFldCd
Upon Request	Yes (X)	UponRequestInd

Books In Care Of Detail BooksInCareOfDetail

Business Name BusinessName

Field	Value	IRS element (for citing)
Business Name Line1	KATHARINE WARDLE	BusinessNameLine1Txt

Field	Value	IRS element (for citing)
Phone	8582001800	PhoneNum

US Address USAddress

Field	Value	IRS element (for citing)
Address Line1	4120 CAPRICORN LANE	AddressLine1Txt
City	LA JOLLA	CityNm
State Abbreviation	CA	StateAbbreviationCd
ZIP	92037	ZIPCd

Form990 Part VII Section A Form990PartVIISectionAGrp (20 entries)

TitleTitleTxt	Average Hours Per WeekAverageHoursPerWeekRt	Individual Trustee Or DirectorIndividualTrusteeOrDirectorInd	OfficerOfficerInd	Reportable Comp From OrgReportableCompFromOrgAmt	Reportable Comp From Rltd OrgReportableCompFromRltdOrgAmt	Other CompensationOtherCompensationAmt	Key EmployeeKeyEmployeeInd	Highest Compensated EmployeeHighestCompensatedEmployeeInd
VENTER JOHN CRAIG
CHAIRMAN & CEO	40.00	Yes (X)	Yes (X)	$1,190,386	$0	$18,720
KOWALSKI HEATHER
CHIEF OPERATING OFFICER	40.00	Yes (X)	Yes (X)	$359,154	$0	$19,533
PEAKE ANTONY G
VP RESEARCH ADMINISTRATION	40.00			$301,718	$0	$8,314	Yes (X)
SCHEUERMANN RICHARD H
DIRECTOR, LA JOLLA CAMPUS	40.00			$282,405	$0	$26,860	Yes (X)
MULLEN JILL
SR. VP OF PHILANTHROPY	32.00			$281,136	$0	$27,622		Yes (X)
YUMUL MARY
VP OF HUMAN RESOURCES	40.00			$256,429	$0	$14,463		Yes (X)
STOUT MARTIN
CHIEF TECHNOLOGY OFFICER	40.00			$220,186	$0	$13,652	Yes (X)
SINGH INDRESH
SR. SOFTWARE ENGINEER	40.00			$217,234	$0	$12,243		Yes (X)
STAYEAS TIMOTHY
NETWORK TEAM LEAD	40.00			$214,596	$0	$14,204		Yes (X)
FOUTS DERRICK
PROFESSOR	40.00			$211,599	$0	$7,712		Yes (X)
SHADFAN AIDA
VP OF FINANCE (THRU 09/23)	40.00		Yes (X)	$202,897	$0	$7,858
ADELSON JULIE
VP, LEG. AFFRS/GENERAL COUNSEL	20.00		Yes (X)	$196,958	$0	$6,600
WARDLE KATHARINE
TREAS/VP OF FINANCE (FROM 09/23)	40.00		Yes (X)	$139,527	$0	$7,989
BADR-EL-DIN AMIN PHD
TRUSTEE	1.00	Yes (X)		$0	$0	$0
BRENNER DAVID
TRUSTEE (FROM 2/8/23)	1.00	Yes (X)		$0	$0	$0
NORRBY ERLING
TRUSTEE	1.00	Yes (X)		$0	$0	$0
PERRY MEREDITH
TRUSTEE (FROM 2/8/23)	1.00	Yes (X)		$0	$0	$0
RUGGLES RUDY
TRUSTEE	1.00	Yes (X)		$0	$0	$0
WEI WU
TRUSTEE	1.00	Yes (X)		$0	$0	$0
WOLF RICHMOND
TRUSTEE	1.00	Yes (X)		$0	$0	$0

Field	Value	IRS element (for citing)
Total Reportable Comp From Org	$4,074,225	TotalReportableCompFromOrgAmt
Tot Reportable Comp Rltd Org	$0	TotReportableCompRltdOrgAmt
Total Other Compensation	$185,770	TotalOtherCompensationAmt
Indiv Rcvd Greater Than100 K	34	IndivRcvdGreaterThan100KCnt
Former Ofcr Employees Listed	0	FormerOfcrEmployeesListedInd
Total Comp Greater Than150 K	Yes (1)	TotalCompGreaterThan150KInd
Compensation From Other Srcs	0	CompensationFromOtherSrcsInd

Contractor Compensation ContractorCompensationGrp (2 entries)

Address Line1ContractorAddress/USAddress/AddressLine1Txt	CityContractorAddress/USAddress/CityNm	State AbbreviationContractorAddress/USAddress/StateAbbreviationCd	ZIPContractorAddress/USAddress/ZIPCd	ServicesServicesDesc	CompensationCompensationAmt
MOSS ADAMS LLP
4747 EXECUTIVE DRIVE SUITE 1300	SAN DIEGO	CA	92121	ACCOUNTING AND AUDIT SERVICES	$145,815
TB CONSULTING
8328 E HARTFORD DRIVE SUITE 102	SCOTTSDALE	AZ	85255	COMPUTER SERVICE CONSULTANT	$145,115

Field	Value	IRS element (for citing)
Cntrct Rcvd Greater Than100 K	2	CntrctRcvdGreaterThan100KCnt
Government Grants	$12,889,795	GovernmentGrantsAmt
All Other Contributions	$2,215,029	AllOtherContributionsAmt
Total Contributions	$15,104,824	TotalContributionsAmt

Investment Income InvestmentIncomeGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$627,098	TotalRevenueColumnAmt
Exclusion	$627,098	ExclusionAmt

Gross Amount Sales Assets GrossAmountSalesAssetsGrp

Field	Value	IRS element (for citing)
Securities	$4,681,723	SecuritiesAmt

Less Cost Oth Basis Sales Expnss LessCostOthBasisSalesExpnssGrp

Field	Value	IRS element (for citing)
Securities	$5,248,840	SecuritiesAmt
Other	$41,648	OtherAmt

Gain Or Loss GainOrLossGrp

Field	Value	IRS element (for citing)
Securities	-$567,117	SecuritiesAmt
Other	-$41,648	OtherAmt

Net Gain Or Loss Investments NetGainOrLossInvestmentsGrp

Field	Value	IRS element (for citing)
Total Revenue Column	-$608,765	TotalRevenueColumnAmt
Exclusion	-$608,765	ExclusionAmt

Other Revenue Misc OtherRevenueMiscGrp

Field	Value	IRS element (for citing)
Desc	K-1 PASSTHROUGH	Desc
Business	900001	BusinessCd
Total Revenue Column	$9,582	TotalRevenueColumnAmt
Unrelated Business Revenue	$9,582	UnrelatedBusinessRevenueAmt

Field	Value	IRS element (for citing)
Other Revenue Total	$9,582	OtherRevenueTotalAmt

Total Revenue TotalRevenueGrp

Field	Value	IRS element (for citing)
Total Revenue Column	$15,132,739	TotalRevenueColumnAmt
Related Or Exempt Func Income	$0	RelatedOrExemptFuncIncomeAmt
Unrelated Business Revenue	$9,582	UnrelatedBusinessRevenueAmt
Exclusion	$18,333	ExclusionAmt

Grants To Domestic Orgs GrantsToDomesticOrgsGrp

Field	Value	IRS element (for citing)
Total	$2,412,163	TotalAmt
Program Services	$2,412,163	ProgramServicesAmt

Foreign Grants ForeignGrantsGrp

Field	Value	IRS element (for citing)
Total	$71,236	TotalAmt
Program Services	$71,236	ProgramServicesAmt

Comp Current Ofcr Directors CompCurrentOfcrDirectorsGrp

Field	Value	IRS element (for citing)
Total	$3,002,758	TotalAmt
Management And General	$3,002,758	ManagementAndGeneralAmt

Other Salaries And Wages OtherSalariesAndWagesGrp

Field	Value	IRS element (for citing)
Total	$9,486,427	TotalAmt
Program Services	$6,126,044	ProgramServicesAmt
Management And General	$3,005,073	ManagementAndGeneralAmt
Fundraising	$355,310	FundraisingAmt

Pension Plan Contributions PensionPlanContributionsGrp

Field	Value	IRS element (for citing)
Total	$273,405	TotalAmt
Program Services	$168,167	ProgramServicesAmt
Management And General	$95,483	ManagementAndGeneralAmt
Fundraising	$9,755	FundraisingAmt

Other Employee Benefits OtherEmployeeBenefitsGrp

Field	Value	IRS element (for citing)
Total	$57,877	TotalAmt
Program Services	$49,956	ProgramServicesAmt
Management And General	$5,024	ManagementAndGeneralAmt
Fundraising	$2,897	FundraisingAmt

Payroll Taxes PayrollTaxesGrp

Field	Value	IRS element (for citing)
Total	$742,525	TotalAmt
Program Services	$367,437	ProgramServicesAmt
Management And General	$353,777	ManagementAndGeneralAmt
Fundraising	$21,311	FundraisingAmt

Fees For Services Legal FeesForServicesLegalGrp

Field	Value	IRS element (for citing)
Total	$130,759	TotalAmt
Management And General	$130,759	ManagementAndGeneralAmt

Fees For Services Accounting FeesForServicesAccountingGrp

Field	Value	IRS element (for citing)
Total	$158,050	TotalAmt
Management And General	$158,050	ManagementAndGeneralAmt

Fees For Srvc Invst Mgmnt Fees FeesForSrvcInvstMgmntFeesGrp

Field	Value	IRS element (for citing)
Total	$104,695	TotalAmt
Management And General	$104,695	ManagementAndGeneralAmt

Fees For Services Other FeesForServicesOtherGrp

Field	Value	IRS element (for citing)
Total	$290,985	TotalAmt
Program Services	$130,693	ProgramServicesAmt
Management And General	$160,292	ManagementAndGeneralAmt

Office Expenses OfficeExpensesGrp

Field	Value	IRS element (for citing)
Total	$103,996	TotalAmt
Program Services	$81,844	ProgramServicesAmt
Management And General	$18,454	ManagementAndGeneralAmt
Fundraising	$3,698	FundraisingAmt

Information Technology InformationTechnologyGrp

Field	Value	IRS element (for citing)
Total	$698,310	TotalAmt
Program Services	$184,783	ProgramServicesAmt
Management And General	$513,527	ManagementAndGeneralAmt

Occupancy OccupancyGrp

Field	Value	IRS element (for citing)
Total	$1,196,618	TotalAmt
Program Services	$300,737	ProgramServicesAmt
Management And General	$890,702	ManagementAndGeneralAmt
Fundraising	$5,179	FundraisingAmt

Travel TravelGrp

Field	Value	IRS element (for citing)
Total	$172,991	TotalAmt
Program Services	$96,071	ProgramServicesAmt
Management And General	$60,995	ManagementAndGeneralAmt
Fundraising	$15,925	FundraisingAmt

Depreciation Depletion DepreciationDepletionGrp

Field	Value	IRS element (for citing)
Total	$415,542	TotalAmt
Program Services	$138,190	ProgramServicesAmt
Management And General	$277,352	ManagementAndGeneralAmt

Insurance InsuranceGrp

Field	Value	IRS element (for citing)
Total	$392,982	TotalAmt
Management And General	$392,982	ManagementAndGeneralAmt

Other Expenses OtherExpensesGrp (2 entries)

DescDesc	TotalTotalAmt	Program ServicesProgramServicesAmt	Management And GeneralManagementAndGeneralAmt	FundraisingFundraisingAmt
LAB EQUIPMENT AND SUPPL	$1,312,681	$1,054,937	$257,744
ALL OTHER EXPENSES	$821,674	$86,631	$720,720	$14,323

Total Functional Expenses TotalFunctionalExpensesGrp

Field	Value	IRS element (for citing)
Total	$21,845,674	TotalAmt
Program Services	$11,268,889	ProgramServicesAmt
Management And General	$10,148,387	ManagementAndGeneralAmt
Fundraising	$428,398	FundraisingAmt

Cash Non Interest Bearing CashNonInterestBearingGrp

Field	Value	IRS element (for citing)
BOY	$5,102,233	BOYAmt
EOY	$2,971,911	EOYAmt

Savings And Temp Cash Invst SavingsAndTempCashInvstGrp

Field	Value	IRS element (for citing)
BOY	$395,507	BOYAmt
EOY	$1,274,704	EOYAmt

Pledges And Grants Receivable PledgesAndGrantsReceivableGrp

Field	Value	IRS element (for citing)
BOY	$15,575,492	BOYAmt
EOY	$13,669,583	EOYAmt

Accounts Receivable AccountsReceivableGrp

Field	Value	IRS element (for citing)
BOY	$7,507	BOYAmt
EOY	$11,598	EOYAmt

Prepaid Expenses Defrd Charges PrepaidExpensesDefrdChargesGrp

Field	Value	IRS element (for citing)
BOY	$311,397	BOYAmt
EOY	$576,720	EOYAmt

Field	Value	IRS element (for citing)
Land Bldg Equip Cost Or Other Bss	$14,973,953	LandBldgEquipCostOrOtherBssAmt
Land Bldg Equip Accum Deprec	$13,367,545	LandBldgEquipAccumDeprecAmt

Land Bldg Equip Basis Net LandBldgEquipBasisNetGrp

Field	Value	IRS element (for citing)
BOY	$1,858,655	BOYAmt
EOY	$1,606,408	EOYAmt

Investments Pub Traded Sec InvestmentsPubTradedSecGrp

Field	Value	IRS element (for citing)
BOY	$27,086,686	BOYAmt
EOY	$23,360,705	EOYAmt

Investments Other Securities InvestmentsOtherSecuritiesGrp

Field	Value	IRS element (for citing)
BOY	$689,927	BOYAmt
EOY	$553,787	EOYAmt

Other Assets Total OtherAssetsTotalGrp

Field	Value	IRS element (for citing)
BOY	$5,280,363	BOYAmt
EOY	$4,956,612	EOYAmt

Total Assets TotalAssetsGrp

Field	Value	IRS element (for citing)
BOY	$56,307,767	BOYAmt
EOY	$48,982,028	EOYAmt

Accounts Payable Accr Expnss AccountsPayableAccrExpnssGrp

Field	Value	IRS element (for citing)
BOY	$2,689,803	BOYAmt
EOY	$2,674,079	EOYAmt

Deferred Revenue DeferredRevenueGrp

Field	Value	IRS element (for citing)
BOY	$2,973,249	BOYAmt
EOY	$4,052,856	EOYAmt

Other Liabilities OtherLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$3,739,563	BOYAmt
EOY	$3,299,712	EOYAmt

Total Liabilities TotalLiabilitiesGrp

Field	Value	IRS element (for citing)
BOY	$9,402,615	BOYAmt
EOY	$10,026,647	EOYAmt

Field	Value	IRS element (for citing)
Organization Follows FASB117	Yes (X)	OrganizationFollowsFASB117Ind

No Donor Restriction Net Assets NoDonorRestrictionNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$34,764,101	BOYAmt
EOY	$29,780,872	EOYAmt

Donor Restriction Net Assets DonorRestrictionNetAssetsGrp

Field	Value	IRS element (for citing)
BOY	$12,141,051	BOYAmt
EOY	$9,174,509	EOYAmt

Total Net Assets Fund Balance TotalNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$46,905,152	BOYAmt
EOY	$38,955,381	EOYAmt

Tot Liab Net Assets Fund Balance TotLiabNetAssetsFundBalanceGrp

Field	Value	IRS element (for citing)
BOY	$56,307,767	BOYAmt
EOY	$48,982,028	EOYAmt

Field	Value	IRS element (for citing)
Info In Schedule O Part XI	Yes (X)	InfoInScheduleOPartXIInd
Reconcilation Revenue Expnss	-$6,712,935	ReconcilationRevenueExpnssAmt
Net Unrlzd Gains Losses Invst	$1,742,746	NetUnrlzdGainsLossesInvstAmt
Other Changes In Net Assets	-$2,979,582	OtherChangesInNetAssetsAmt
Method Of Accounting Accrual	Yes (X)	MethodOfAccountingAccrualInd
Accountant Compile Or Review	0	AccountantCompileOrReviewInd
FS Audited	Yes (1)	FSAuditedInd

FS Audited Basis FSAuditedBasisGrp

Field	Value	IRS element (for citing)
Separate Basis Fincl Stmt	Yes (X)	SeparateBasisFinclStmtInd

Field	Value	IRS element (for citing)
Audit Committee	Yes (1)	AuditCommitteeInd
Federal Grant Audit Required	Yes (1)	FederalGrantAuditRequiredInd
Federal Grant Audit Performed	Yes (1)	FederalGrantAuditPerformedInd

Schedule A IRS990ScheduleA

Field	Value	IRS element (for citing)
Public Organization170	Yes (X)	PublicOrganization170Ind

Gifts Grants Contri Rcvd170 GiftsGrantsContriRcvd170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$21,442,951	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$18,613,419	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$24,288,254	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$16,500,408	CurrentTaxYearMinus1YearAmt
Current Tax Year	$15,104,824	CurrentTaxYearAmt
Total	$95,949,856	TotalAmt

Govt Furn Srvc Fclts Vl170 GovtFurnSrvcFcltsVl170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus1 Year	$14,850,000	CurrentTaxYearMinus1YearAmt
Total	$14,850,000	TotalAmt

Total Calendar Year170 TotalCalendarYear170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$21,442,951	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$18,613,419	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$24,288,254	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$31,350,408	CurrentTaxYearMinus1YearAmt
Current Tax Year	$15,104,824	CurrentTaxYearAmt
Total	$110,799,856	TotalAmt

Field	Value	IRS element (for citing)
Public Support Total170	$110,799,856	PublicSupportTotal170Amt

Gross Investment Income170 GrossInvestmentIncome170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus4 Years	$1,158,537	CurrentTaxYearMinus4YearsAmt
Current Tax Year Minus3 Years	$905,885	CurrentTaxYearMinus3YearsAmt
Current Tax Year Minus2 Years	$855,862	CurrentTaxYearMinus2YearsAmt
Current Tax Year Minus1 Year	$726,080	CurrentTaxYearMinus1YearAmt
Current Tax Year	$627,098	CurrentTaxYearAmt
Total	$4,273,462	TotalAmt

Unrelated Business Net Incm170 UnrelatedBusinessNetIncm170Grp

Field	Value	IRS element (for citing)
Current Tax Year Minus1 Year	$15,119	CurrentTaxYearMinus1YearAmt
Current Tax Year	$6,041	CurrentTaxYearAmt
Total	$21,160	TotalAmt

Field	Value	IRS element (for citing)
Total Support	$115,094,478	TotalSupportAmt
Gross Receipts Rltd Activities	$669,522	GrossReceiptsRltdActivitiesAmt
Public Support CY170	0.96270	PublicSupportCY170Pct
Public Support PY170	0.93420	PublicSupportPY170Pct
Thirty Thr Pct Suprt Tests CY170	Yes (X)	ThirtyThrPctSuprtTestsCY170Ind

Schedule B IRS990ScheduleB

Contributor Information ContributorInformationGrp

Field	Value	IRS element (for citing)
Contributor	RESTRICTED	ContributorNum

Contributor Business Name ContributorBusinessName

Field	Value	IRS element (for citing)
Business Name Line1	RESTRICTED	BusinessNameLine1

Contributor US Address ContributorUSAddress

Field	Value	IRS element (for citing)
Address Line1	RESTRICTED	AddressLine1
Address Line2	RESTRICTED	AddressLine2
City	RESTRICTED	City
State	RESTRICTED	State
ZIP Code	RESTRICTED	ZIPCode

Field	Value	IRS element (for citing)
Total Contributions	RESTRICTED	TotalContributionsAmt

Schedule D IRS990ScheduleD

Art Public Exhibition Amounts ArtPublicExhibitionAmountsGrp

Field	Value	IRS element (for citing)
Assets Included	$2,545,000	AssetsIncludedAmt

Field	Value	IRS element (for citing)
Collection Used Pub Exhibition	Yes (X)	CollectionUsedPubExhibitionInd
Coll Used Scholarly Rsrch	Yes (X)	CollUsedScholarlyRsrchInd
Collection Used Preservation	Yes (X)	CollectionUsedPreservationInd
Solicited Assets Sale	0	SolicitedAssetsSaleInd

Leasehold Improvements LeaseholdImprovementsGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$1,395,244	OtherCostOrOtherBasisAmt
Depreciation	$675,640	DepreciationAmt
Book Value	$719,604	BookValueAmt

Equipment EquipmentGrp

Field	Value	IRS element (for citing)
Other Cost Or Other Basis	$13,578,709	OtherCostOrOtherBasisAmt
Depreciation	$12,691,905	DepreciationAmt
Book Value	$886,804	BookValueAmt

Field	Value	IRS element (for citing)
Total Book Value Land Buildings	$1,606,408	TotalBookValueLandBuildingsAmt

Other Assets Org OtherAssetsOrgGrp (2 entries)

DescDesc	Book ValueBookValueAmt
OTHER ASSETS	$2,725,900
RIGHT OF USE ASSETS	$2,230,712

Field	Value	IRS element (for citing)
Total Book Value Other Assets	$4,956,612	TotalBookValueOtherAssetsAmt

Other Liabilities Org OtherLiabilitiesOrgGrp

Field	Value	IRS element (for citing)
Desc	LEASE LIABILITY	Desc
Amt	$3,299,712	Amt

Field	Value	IRS element (for citing)
Total Liability	$3,299,712	TotalLiabilityAmt
Footnote Text	Yes (X)	FootnoteTextInd
Total Rev Etc Audited Fincl Stmt	$16,761,208	TotalRevEtcAuditedFinclStmtAmt
Net Unrealized Gains Invst	$1,742,746	NetUnrealizedGainsInvstAmt
Revenue Not Reported	$1,742,746	RevenueNotReportedAmt
Revenue Subtotal	$15,018,462	RevenueSubtotalAmt
Investment Expenses Not Incld	$104,695	InvestmentExpensesNotIncldAmt
Other Revenues Not Included	$9,582	OtherRevenuesNotIncludedAmt
Revenue Not Reported Fincl Stmt	$114,277	RevenueNotReportedFinclStmtAmt
Total Revenue Per Form990	$15,132,739	TotalRevenuePerForm990Amt
Tot Expns Etc Audited Fincl Stmt	$24,710,979	TotExpnsEtcAuditedFinclStmtAmt
Donated Services Use Fclts	$2,970,000	DonatedServicesUseFcltsAmt
Expenses Not Reported	$2,970,000	ExpensesNotReportedAmt
Expenses Subtotal	$21,740,979	ExpensesSubtotalAmt
Investment Expenses Not Incld2	$104,695	InvestmentExpensesNotIncld2Amt
Expenses Not Rpt Fincl Stmt	$104,695	ExpensesNotRptFinclStmtAmt
Total Expenses Per Form990	$21,845,674	TotalExpensesPerForm990Amt

Supplemental Information Detail SupplementalInformationDetail (3 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
PART III, LINE 4:	COLLECTION OF SCIENTIFIC WRITINGS RELEVANT TO GENOMIC RESEARCH.
PART X, LINE 2:	THE INSTITUTE IS A NOT-FOR-PROFIT ORGANIZATION EXEMPT FROM FEDERAL INCOME TAXES UNDER SECTION 501(C)(3) OF THE INTERNAL REVENUE CODE. THE INSTITUTE DOES NOT BELIEVE THERE ARE ANY MATERIAL UNCERTAIN TAX POSITIONS AND ACCORDINGLY, NO PROVISION FOR INCOME TAXES HAS BEEN MADE IN THE ACCOMPANYING FINANCIAL STATEMENTS. THE INSTITUTE IS SUBJECT TO ROUTINE AUDITS BY TAXING JURISDICTIONS; HOWEVER, THERE ARE CURRENTLY NO AUDITS FOR ANY TAX PERIOD IN PROGRESS.
PART XI, LINE 4B - OTHER ADJUSTMENTS:	K-1 PASSTHROUGH 9,582.

Schedule F IRS990ScheduleF

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (1)	GrantRecordsMaintainedInd

Account Activities Outside US AccountActivitiesOutsideUSGrp (3 entries)

RegionRegionTxt	Type Of Activities ConductedTypeOfActivitiesConductedTxt	Region Total ExpendituresRegionTotalExpendituresAmt	Specific Services ProvidedSpecificServicesProvidedTxt
CAYMAN ISLANDS	INVESTMENTS	$145,119
CENTRAL AMERICA AND THE CARIBBEAN - ANTIGUA & BARBUDA, ARUBA, BAHAMAS,	PROGRAM SERVICES	$40,152	RESEARCH SUBGRANTS
SOUTH AMERICA	PROGRAM SERVICES	$31,084	RESEARCH SUBGRANTS

Field	Value	IRS element (for citing)
Subtotal Offices	0	SubtotalOfficesCnt
Subtotal Employees	0	SubtotalEmployeesCnt
Continuation Total Office	0	ContinuationTotalOfficeCnt
Continuation Total Employee	0	ContinuationTotalEmployeeCnt
Total Office	0	TotalOfficeCnt
Total Employee	0	TotalEmployeeCnt
Subtotal Spent	$216,355	SubtotalSpentAmt
Continuation Spent	$0	ContinuationSpentAmt
Total Spent	$216,355	TotalSpentAmt

Grants To Org Outside US GrantsToOrgOutsideUSGrp (2 entries)

RegionRegionTxt	Purpose Of GrantPurposeOfGrantTxt	Cash GrantCashGrantAmt	Manner Of Cash DisbursementMannerOfCashDisbursementTxt	Non Cash AssistanceNonCashAssistanceAmt
CENTRAL AMERICA AND THE CARIBBEAN	UNIVERSITY OF WEST INDIES, PROGRAM SERVICES/RESEARCH SUBGRANTS	$40,152	WIRE OR CHECK	$0
SOUTH AMERICA	RESEARCH SUBGRANTS	$31,084	WIRE OR CHECK	$0

Field	Value	IRS element (for citing)
Total501c3 Org	2	Total501c3OrgCnt
Total Other Org	0	TotalOtherOrgCnt
Transfer To Foreign Corp	0	TransferToForeignCorpInd
Interest In Foreign Trust	0	InterestInForeignTrustInd
Foreign Corp Ownership	0	ForeignCorpOwnershipInd
Passive Foreign Investmest Co	0	PassiveForeignInvestmestCoInd
Foreign Partnership	Yes (1)	ForeignPartnershipInd
Boycott Countries	0	BoycottCountriesInd

Supplemental Information Detail SupplementalInformationDetail (3 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
PART I, LINE 2:	EACH SUBGRANT IS A PASS THROUGH GRANT FROM A FEDERAL OR NON-FEDERAL GRANT OR CONTRACT AWARDED TO J. CRAIG VENTER INSTITUTE. ALL EXPENSES ARE MONITORED AS INVOICED AT LEAST QUARTERLY, BUT IN MOST CASES MONTHLY. THE INVOICES ARE REVIEWED AND APPROVED BASED ON RECEIPT OF GOODS OR SERVICES AND AGAINST AN APPROVED BUDGET.
PART I, LINE 3:	ACCRUAL BASIS
PART II, LINE 1:	ACCRUAL BASIS

Schedule I IRS990ScheduleI

Field	Value	IRS element (for citing)
Grant Records Maintained	Yes (1)	GrantRecordsMaintainedInd

Recipient Table RecipientTable (12 entries)

Address Line1USAddress/AddressLine1Txt	CityUSAddress/CityNm	State AbbreviationUSAddress/StateAbbreviationCd	ZIPUSAddress/ZIPCd	Recipient EINRecipientEIN	IRC SectionIRCSectionDesc	Cash GrantCashGrantAmt	Non Cash AssistanceNonCashAssistanceAmt	Purpose Of GrantPurposeOfGrantTxt
CASE WESTERN RESERVE UNIVERSITY
10900 EUCLID AVENUE NORD HALL	CLEVELAND	OH	441067037	341018992	501(C)(3)	$409,716	$0	RESEARCH SUBGRANT
COLORADO STATE UNIVERSITY
6015 CAMPUS DELIVERY	FORT COLLINS	CO	80523	846000545	GOVT	$147,113	$0	RESEARCH SUBGRANT
DUKE UNIVERSITY
PO BOX 602651	CHARLOTTE	NC	282602651	560532129	501(C)(3)	$201,837	$0	RESEARCH SUBGRANT
GLOBAL ALGAE INNOVATIONS
486 LIVE OAK DRIVE	EL CAJON	CA	92020	455319556		$22,057	$0	RESEARCH SUBGRANT
LELAND STANFORD JR UNIVERSITY
3145 PORTER DRIVE	PALO ALTO	CA	94304	941156365	501(C)(3)	$79,880	$0	RESEARCH SUBGRANT
NORTHWESTERN UNIVERSITY
633 CLARK STREET G547	EVANSTON	IL	60208	362167817	501(C)(3)	$87,777	$0	RESEARCH SUBGRANT
RHODE ISLAND HOSPITAL
1 HOPPIN STREET BOX 42 SUITE 1300	PROVIDENCE	RI	029034923	050258954	501(C)(3)	$256,018	$0	RESEARCH SUBGRANT
SANTA FE INSTITUTE
1399 HYDE PARK ROAD	SANTA FE	NM	875018943	850325494	501(C)(3)	$30,395	$0	RESEARCH SUBGRANT
UNIVERSITY OF ALABAMA BIRMINGHAM
1720 2ND AVENUE SOUTH	BIRMINGHAM	AL	35294	636005396	GOVT	$46,654	$0	RESEARCH SUBGRANT
UNIVERSITY OF CALIFORNIA SAN DIEGO
9500 GILMAN DRIVE	LA JOLLA	CA	92037	566001393	GOVT	$628,139	$0	RESEARCH SUBGRANT
UNIVERSITY OF MARYLAND
4300 TERRAPIN TRAIL	COLLEGE PARK	MD	20742	526002033	GOVT	$200,549	$0	RESEARCH SUBGRANT
VANDERBILT UNIVERSITY
2201 WEST END AVENUE	NASHVILLE	TN	37235	620476822	501(C)(3)	$302,028	$0	RESEARCH SUBGRANT

Field	Value	IRS element (for citing)
Total501c3 Org	11	Total501c3OrgCnt
Total Other Org	1	TotalOtherOrgCnt

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	PART I, LINE 2:	FormAndLineReferenceDesc
Explanation	EACH SUBGRANT IS A PASS THROUGH GRANT FROM A FEDERAL OR NON-FEDERAL GRANT OR CONTRACT AWARDED TO J. CRAIG VENTER INSTITUTE. ALL EXPENSES ARE MONITORED AS INVOICED AT LEAST QUARTERLY, BUT IN MOST CASES MONTHLY. THE INVOICES ARE REVIEWED AND APPROVED BASED ON RECEIPT OF GOODS OR SERVICES AND AGAINST AN APPROVED BUDGET.	ExplanationTxt

Schedule J IRS990ScheduleJ

Field	Value	IRS element (for citing)
Idemnification Gross Up Pmts	Yes (X)	IdemnificationGrossUpPmtsInd
Written Policy Ref T And E Expnss	Yes (1)	WrittenPolicyRefTAndEExpnssInd
Substantiation Required	Yes (1)	SubstantiationRequiredInd
Compensation Committee	Yes (X)	CompensationCommitteeInd
Independent Consultant	Yes (X)	IndependentConsultantInd
Compensation Survey	Yes (X)	CompensationSurveyInd
Board Or Committee Approval	Yes (X)	BoardOrCommitteeApprovalInd
Severance Payment	0	SeverancePaymentInd
Supplemental Nonqual Rtr Plan	0	SupplementalNonqualRtrPlanInd
Equity Based Comp Arrngm	0	EquityBasedCompArrngmInd
Comp Based On Revenue Of Flng Org	0	CompBasedOnRevenueOfFlngOrgInd
Comp Bsd On Rev Related Orgs	0	CompBsdOnRevRelatedOrgsInd
Comp Bsd Net Earns Flng Org	0	CompBsdNetEarnsFlngOrgInd
Comp Bsd Net Earns Rltd Orgs	0	CompBsdNetEarnsRltdOrgsInd
Any Non Fixed Payments	0	AnyNonFixedPaymentsInd
Initial Contract Exception	0	InitialContractExceptionInd

Rltd Org Officer Trst Key Empl RltdOrgOfficerTrstKeyEmplGrp (12 entries)

TitleTitleTxt	Base Compensation Filing OrgBaseCompensationFilingOrgAmt	Compensation Based On Rltd OrgsCompensationBasedOnRltdOrgsAmt	Bonus Filing OrganizationBonusFilingOrganizationAmount	Bonus Related OrganizationsBonusRelatedOrganizationsAmt	Other Compensation Filing OrgOtherCompensationFilingOrgAmt	Other Compensation Rltd OrgsOtherCompensationRltdOrgsAmt	Deferred Compensation Flng OrgDeferredCompensationFlngOrgAmt	Deferred Comp Rltd OrgsDeferredCompRltdOrgsAmt	Nontaxable Benefits Filing OrgNontaxableBenefitsFilingOrgAmt	Nontaxable Benefits Rltd OrgsNontaxableBenefitsRltdOrgsAmt	Total Compensation Filing OrgTotalCompensationFilingOrgAmt	Total Compensation Rltd OrgsTotalCompensationRltdOrgsAmt	Comp Report Prior990 Filing OrgCompReportPrior990FilingOrgAmt	Comp Report Prior990 Rltd OrgsCompReportPrior990RltdOrgsAmt
VENTER JOHN CRAIG
CHAIRMAN & CEO	$1,160,389	$0	$0	$0	$29,997	$0	$13,200	$0	$5,520	$0	$1,209,106	$0	$0	$0
KOWALSKI HEATHER
CHIEF OPERATING OFFICER	$341,154	$0	$0	$0	$18,000	$0	$13,200	$0	$6,333	$0	$378,687	$0	$0	$0
PEAKE ANTONY G
VP RESEARCH ADMINISTRATION	$278,322	$0	$0	$0	$23,396	$0	$8,314	$0	$0	$0	$310,032	$0	$0	$0
SCHEUERMANN RICHARD H
DIRECTOR, LA JOLLA CAMPUS	$261,409	$0	$0	$0	$20,996	$0	$10,624	$0	$16,236	$0	$309,265	$0	$0	$0
MULLEN JILL
SR. VP OF PHILANTHROPY	$263,468	$0	$0	$0	$17,668	$0	$10,266	$0	$17,356	$0	$308,758	$0	$0	$0
YUMUL MARY
VP OF HUMAN RESOURCES	$235,629	$0	$0	$0	$20,800	$0	$9,533	$0	$4,930	$0	$270,892	$0	$0	$0
STOUT MARTIN
CHIEF TECHNOLOGY OFFICER	$213,427	$0	$0	$0	$6,759	$0	$6,206	$0	$7,446	$0	$233,838	$0	$0	$0
SINGH INDRESH
SR. SOFTWARE ENGINEER	$191,806	$0	$0	$0	$25,428	$0	$7,775	$0	$4,468	$0	$229,477	$0	$0	$0
STAYEAS TIMOTHY
NETWORK TEAM LEAD	$194,354	$0	$0	$0	$20,242	$0	$8,247	$0	$5,957	$0	$228,800	$0	$0	$0
FOUTS DERRICK
PROFESSOR	$181,599	$0	$0	$0	$30,000	$0	$7,712	$0	$0	$0	$219,311	$0	$0	$0
SHADFAN AIDA
VP OF FINANCE (THRU 09/23)	$188,690	$0	$0	$0	$14,207	$0	$7,858	$0	$0	$0	$210,755	$0	$0	$0
ADELSON JULIE
VP, LEG. AFFRS/GENERAL COUNSEL	$168,158	$0	$0	$0	$28,800	$0	$6,600	$0	$0	$0	$203,558	$0	$0	$0

Supplemental Information Detail SupplementalInformationDetail

Field	Value	IRS element (for citing)
Form And Line Reference	PART I, LINE 1A	FormAndLineReferenceDesc
Explanation	SCHEDULE J, PART I, LINE 1A: TAX INDEMIFICATION AND GROSS-UP PAYMENTS - CERTAIN AWARDS ARE GROSSED UP FOR INCOME TAX AND INCLUDED AS TAXABLE COMPENSATION.	ExplanationTxt

Schedule O IRS990ScheduleO

Supplemental Information Detail SupplementalInformationDetail (6 entries)

Form And Line ReferenceFormAndLineReferenceDesc	ExplanationExplanationTxt
FORM 990, PART VI, SECTION A, LINE 2	BOARD MEMBERS HEATHER KOWALSKI AND J. CRAIG VENTER HAVE A FAMILY RELATIONSHIP.
FORM 990, PART VI, SECTION B, LINE 11B	THE FORM 990 IS REVIEWED BY MANAGEMENT AND THE AUDIT COMMITTEE. A COMPLETE COPY OF THE FORM 990 AND SUPPORTING SCHEDULES WAS PROVIDED TO THE FULL BOARD FOR REVIEW PRIOR TO BEING FILED.
FORM 990, PART VI, SECTION B, LINE 12C	JCVI MONITORS COMPLIANCE TO ITS CONFLICT OF INTEREST POLICY THROUGH AN ANNUAL SOLICITATION OF CONFLICT OF INTEREST STATEMENTS FROM TRUSTEES, OFFICERS, AND EMPLOYEES. IF A PERSON HAS A CONFLICT WITH RESPECT TO A TRANSACTION, SUCH PERSON IS NOT ALLOWED TO VOTE ON THAT TRANSACTION.
FORM 990, PART VI, SECTION B, LINE 15	JCVI USES AN OUTSIDE COMPENSATION CONSULTANT TO PROVIDE A LIST OF COMPARABLE SALARIES FOR THE CEO AND OFFICERS THESE ARE REVIEWED BY THE JCVI COMPENSATION COMMITTEE AND CEO BEFORE A FINAL DETERMINATION IS MADE. THIS PROCESS WAS DOCUMENTED AND LAST DONE IN OCTOBER 2018.
FORM 990, PART VI, SECTION C, LINE 19	THE ORGANIZATION'S FINANCIAL STATEMENTS, GOVERNING DOCUMENTS, AND CONFLICT OF INTEREST POLICY ARE MADE AVAILABLE TO THE PUBLIC UPON REQUEST.
FORM 990, PART XI, LINE 9:	K-1 PASSTHROUGH -9,582. DONATED RENT -2,970,000.