2026-05-12T13:35:25-05:00 2025-12-31 334358135 SAX ADVISORS LLC 389 INTERPACE PARKWAY STE 3 PARSIPPANY NJ 07054 990 2025-01-01 237376197 HUNTINGTON'S DISEASE FOUNDATION HUNT 2129282121 601 WEST 168TH STREET 54 NEW YORK NY 10032 MEGHAN DONALDSON CEO 2129282121 2026-05-12 1 MARQUS WHITE P00053187 9734726250 2026-04-28 2025 2025-03-06 01:10:19Z X MEGHAN DONALDSON 601 WEST 168TH STREET 54 NEW YORK NY 10032 11041255 0 X WWW.HDFOUNDATION.ORG X 1968 CA TO FUND TRANSFORMATIVE RESEARCH TO FIND TREATMENTS, AND ULTIMATELY A CURE, FOR HUNTINGTON'S DISEASE. 17 15 4 45 0 0 6573281 3254595 0 52500 1243205 634776 82735 139798 7899221 4081669 2869473 3152522 0 0 654479 618915 0 0 245674 1000193 554954 4524145 4326391 3375076 -244722 21978294 23135759 2828419 2314242 19149875 20821517 X TO FUND TRANSFORMATIVE RESEARCH TO FIND TREATMENTS, AND ULTIMATELY A CURE, FOR HUNTINGTON'S DISEASE. 0 0 3796690 3152522 52500 HUNTINGTON'S DISEASE FOUNDATION (HDF) ADVANCES PARADIGM-CHANGING HUNTINGTON'S DISEASE (HD) RESEARCH THROUGH A COLLABORATIVE APPROACH TO SCIENTIFIC DISCOVERY. WE INVEST IN RESEARCH BY PROVIDING SENIOR SCIENTISTS WITH GRANTS, INCLUDING OUR MILLION-DOLLAR TRANSFORMATIVE RESEARCH AWARDS, WHICH BEGAN IN 2023, AND FUNDING THE WORK OF EARLY CAREER SCIENTISTS THROUGH POSTDOCTORAL FELLOWSHIPS. WE CHAMPION COLLABORATIVE SCIENCE BY ORGANIZING BOTH SMALL THINKTANK-STYLE WORKSHOPS AND LARGE SCIENTIFIC CONFERENCES WHICH ENABLE EXPERTS IN HD TO SHARE THEIR LATEST DISCOVERIES, EXPLORE CUTTING-EDGE TECHNOLOGIES, AND FORM COLLABORATIONS. WE HIGHLIGHT FOR THE PUBLIC NOTABLE WORK OF SCIENTISTS THROUGH OUR WEBINARS.(CONTINUED ON SCHEDULE O)IN ITS EARLY YEARS, RESEARCH ORGANIZED AND FUNDED BY THE HDF WAS THE CATALYST FOR THE WORK THAT ISOLATED THE GENE THAT CAUSES HUNTINGTON'S DISEASE. THIS FINDING LED TO THE DEVELOPMENT OF A GENETIC TEST FOR HD AND LAUNCHED MODERN RESEARCH EFFORTS. THE HUNTINGTON'S DISEASE FOUNDATION SUPPORTS RESEARCH THROUGH SEVERAL FUNDING OPPORTUNITIES.HDF RESEARCH GRANTS: ONE-YEAR GRANTS PROVIDE SENIOR RESEARCHERS WITH SEED FUNDING TO ENABLE THEM TO COLLECT THE PRELIMINARY DATA NEEDED TO OBTAIN MAJOR, LONG-TERM FUNDING FROM OTHER ORGANIZATIONS, INCLUDING THE NIH.HDF POSTDOCTORAL FELLOWSHIPS: TWO-YEAR FELLOWSHIPS FUND THE WORK OF EARLY-CAREER SCIENTISTS. THESE FELLOWSHIPS ARE INTENDED TO ENCOURAGE AND CULTIVATE INTEREST IN HUNTINGTON'S DISEASE RESEARCH.TRANSFORMATIVE RESEARCH AWARDS: THESE MILLION-DOLLAR RESEARCH AWARDS, HDF'S LARGEST GRANTS, FUND COLLABORATIVE RESEARCH TEAMS TO CREATE INNOVATIVE WAYS TO STUDY NEW PATHOGENIC DISEASE MECHANISMS AND TREATMENT MODALITIES IN HUNTINGTON'S DISEASE.HD CAREER ADVANCEMENT GRANTS: THESE ARE OUR NEWEST AWARDS WITH GRANTS BEGINNING IN 2025. THIS INCUBATOR PROGRAM SUPPORTS YOUNG INVESTIGATORS BY PROVIDING RESOURCES AND TOOLS TO BUILD THE NECESSARY SKILLS TO BRIDGE THE TRANSITION FROM POSTDOCTORAL POSITION TO TENURE-TRACK PRIMARY INVESTIGATOR. OUR GOAL THROUGH THIS PROGRAM AND OUR POSTDOCTORAL FELLOWSHIPS IS TO ENGAGE AND RETAIN THE BRIGHTEST MINDS IN HD RESEARCH BY FUNDING AND MENTORING EARLY-CAREER SCIENTISTS.HDF-FUNDED RESEARCHERS HAVE MADE SIGNIFICANT STRIDES IN APPLYING ADVANCED TECHNIQUES SUCH AS ARTIFICIAL INTELLIGENCE (AI), CRISPR AND BRAIN MAPPING, LEADING TO TREMENDOUS PROMISE FOR POTENTIAL TREATMENTS FOR HUNTINGTON'S DISEASE. 3796690 1 1 0 0 0 0 0 0 0 1 0 0 0 0 1 1 1 0 0 0 1 1 0 0 0 0 0 1 0 1 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 1 11 0 1 4 1 0 0 0 0 0 0 0 0 0 0 0 0 X 17 15 1 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 0 0 CA NY X X CAREY & CO 6469161782 601 WEST 168TH STREET 54 NEW YORK NY 10032 MEGHAN DONALDSON CEO 40.00 X X 50000 0 0 KAREN NEWMAN CHAIR 24.00 X X 72000 0 0 NANCY S WEXLER PHD PRESIDENT 1.00 X X 0 0 0 ANNE B YOUNG MD PHD VICE CHAIR 1.00 X X 0 0 0 BRUCE DONALDSON TREASURER 1.00 X X 0 0 0 ALICE WEXLER PHD SECRETARY 1.00 X X 0 0 0 C FRANK BENNETT PHD DIRECTOR 1.00 X 0 0 0 ROBI BLUMENSTEIN DIRECTOR 1.00 X 0 0 0 SANDY FOX DIRECTOR 1.00 X 0 0 0 TACIE FOX DIRECTOR 1.00 X 0 0 0 BERTA A GEHRY DIRECTOR 1.00 X 0 0 0 FRANK O GEHRY DIRECTOR (THROUGH 12/5/25) 1.00 X 0 0 0 DAVID HOUSMAN PHD DIRECTOR 1.00 X 0 0 0 THOMAS OBERSTEINER DIRECTOR (JOINED 4/25) 1.00 X 0 0 0 LAUREN BAKER PINKUS DIRECTOR 1.00 X 0 0 0 LESLIE M THOMPSON PHD DIRECTOR 1.00 X 0 0 0 DAVID ZWALLY DIRECTOR 1.00 X 0 0 0 MELISSA MOSER DIRECTOR 1.00 X 0 0 0 TIM KELLEHER CFO 6.00 X 31521 0 0 SARAH HERNANDEZ PHD DIR. OF RESEARCH PROGRAMS 40.00 X 155000 0 61927 JULIE PORTER DIR. OF ADMINISTRATION 40.00 X 124000 0 33541 432521 0 95468 2 0 1 0 0 3254595 158189 3254595 PROGRAM EVENTS 900099 52500 52500 52500 496182 496182 7098180 6959586 138594 138594 138594 MISCELLANEOUS 900099 139798 139798 139798 4081669 52500 0 774574 1403692 1403692 1748830 1748830 370448 270727 64521 35200 184852 92885 18485 73482 33542 23478 3355 6709 30073 21052 2706 6315 38000 38000 96596 96596 147505 61843 37662 48000 13828 51 8250 5527 41152 28806 3704 8642 104740 94941 538 9261 6293 4406 566 1321 COMPUTER SUPPORT AND MA 49452 13554 4717 31181 OTHER EXPENSE 38255 32366 2326 3563 POSTAGE & PRINTING 19133 59 2601 16473 4326391 3796690 284027 245674 386234 357497 1654084 1375164 986607 300600 50271 148831 13760642 20950224 5137263 3193 3443 21978294 23135759 17125 111742 2791613 2153747 19681 48753 2828419 2314242 X 3390111 4315422 15759764 16506095 19149875 20821517 21978294 23135759 -244722 1916364 0 X 0 1 X 1 0 X 2827274 4399874 2087245 6573281 3254595 19142269 2827274 4399874 2087245 6573281 3254595 19142269 9871883 9270386 245544 270807 373677 357558 496182 1743768 139069 36718 3396 82735 139798 401716 21287753 52500 0.43550 0.47310 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 10887744 1620851 544387 57373 11906835 10208361 1248253 510418 58452 10887744 8982275 1732681 449114 57481 10208361 11593322 -1958855 579666 72526 8982275 10244052 1932598 512203 71125 11593322 0.71600 0.28400 0 0 0 FUNDS HELD FOR OTHERS 48753 48753 X 5901437 1916364 1916364 3985073 96596 96596 4081669 4229795 0 4229795 96596 96596 4326391 PART X, LINE 2: HDF DOES NOT BELIEVE ITS FINANCIAL STATEMENTS INCLUDE ANY MATERIAL, UNCERTAIN TAX POSITIONS. TAX FILINGS FOR THE PERIODS ENDING DECEMBER 31, 2022 AND LATER ARE SUBJECT TO EXAMINATION BY APPLICABLE TAXING AUTHORITIES. 0 NORTH AMERICA - CANADA AND MEXICO, BUT NOT THE UNITED STATES 0 0 GRANTS TO RECIPIENTS SCIENTIFIC RESEARCH 1648909 EUROPE (INCLUDING ICELAND & GREENLAND) - ALBANIA, ANDORRA, AUSTRIA, BELGIUM 0 0 GRANTS TO RECIPIENTS SCIENTIFIC RESEARCH 99921 0 0 0 0 0 0 1748830 0 1748830 CANADA SCIENTIFIC RESEARCH 1150000 WIRE 0 CANADA SCIENTIFIC RESEARCH 100000 WIRE 0 CANADA SCIENTIFIC RESEARCH 100000 WIRE 0 CANADA SCIENTIFIC RESEARCH 100000 WIRE 0 CANADA SCIENTIFIC RESEARCH 99067 WIRE 0 CANADA SCIENTIFIC RESEARCH 99842 WIRE 0 FRANCE SCIENTIFIC RESEARCH 99921 WIRE 0 0 0 0 0 0 0 PART I, LINE 2: HDF MONITORS THE USE OF ITS GRANTS BY REQUIRING SCIENCE RESEARCH PROGRESS REPORTS EVERY 6 MONTHS FROM ITS GRANTEES WHICH MUST BE APPROVED BY THE HDF'S DIRECTOR OF RESEARCH PROGRAMS AS A CONDITION TO FURTHER PAYMENTS TO THE GRANTEE. HDF PAYS ITS GRANTS IN INSTALLMENTS EVERY SIX MONTHS AND REQUIRES A FINAL REPORT UPON COMPLETION OF THE RESEARCH. 1 CHAN ZUCKERBERG BIOHUB (SAN FRANCISCO) 499 ILLINOIS STREET SAN FRANCISCO CA 94158 882010111 501 (C) (3) 100000 0 SCIENTIFIC RESEARCH MASSACHUSETTS GENERAL HOSPITAL (MASS GENERAL) 399 REVOLUTIONARY DRIVE SOMMERVILLE MA 02114 042697983 501 (C) (3) 100000 0 SCIENTIFIC RESEARCH MASSACHUSETTS GENERAL HOSPITAL (MASS GENERAL) 399 REVOLUTIONARY DRIVE SOMMERVILLE MA 02114 042697983 501 (C) (3) 200000 0 SCIENTIFIC RESEARCH MASSACHUSETTS INSTITUTE OF TECHNOLOGY - MIT 77 MASSACHUSETTS AVENUE CAMBRIDGE MA 021394307 042103594 501 (C) (3) 200000 0 SCIENTIFIC RESEARCH MASSACHUSETTS INSTITUTE OF TECHNOLOGY - MIT 77 MASSACHUSETTS AVENUE CAMBRIDGE MA 021394307 042103594 501 (C) (3) 100000 0 SCIENTIFIC RESEARCH THE CORPORATION OF MERCER UNIVERSITY 1501 MERCER UNIVERSITY DRIVE MACON GA 312071515 580566167 501 (C) (3) 100000 0 SCIENTIFIC RESEARCH THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 485 BROADWAY UNIVERSITY HALL 3RD FLOOR REDWOOD CITY CA 94063 941156365 501 (C) (3) 200000 0 SCIENTIFIC RESEARCH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA LOS ANGELES 405 HILGARD AVENUE LOS ANGELES CA 900957089 956006143 501 (C) (3) 200000 0 SCIENTIFIC RESEARCH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA LOS ANGELES 405 HILGARD AVENUE LOS ANGELES CA 900957089 956006143 501 (C) (3) 50000 0 SCIENTIFIC RESEARCH WASHINGTON UNIVERSITY 325 9TH AVENUE SEATTLE WA 98104 916001537 501 (C) (3) 100000 0 SCIENTIFIC RESEARCH THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 615 WEST 131ST STREET 6TH FLOOR NEW YORK NY 10027 135598093 501 (C) (3) 50000 0 SCIENTIFIC RESEARCH 11 PART I, LINE 2: HDF MONITORS THE USE OF ITS GRANTS BY REQUIRING SCIENCE RESEARCH PROGRESS REPORTS EVERY 6 MONTHS FROM ITS GRANTEES WHICH MUST BE APPROVED BY THE HDF'S DIRECTOR OF RESEARCH PROGRAMS AS A CONDITION TO FURTHER PAYMENTS TO THE GRANTEE. HDF PAYS ITS GRANTS IN INSTALLMENTS EVERY SIX MONTHS AND REQUIRES A FINAL REPORT UPON COMPLETION OF THE RESEARCH. X X 0 0 0 0 0 0 0 0 0 SARAH HERNANDEZ PHD DIR. OF RESEARCH PROGRAMS 155000 0 0 0 0 0 0 0 61927 0 216927 0 0 0 JULIE PORTER DIR. OF ADMINISTRATION 124000 0 0 0 0 0 0 0 33541 0 157541 0 0 0 DAVID HOUSMAN BOARD MEMBER 100000 RESEARCH GRANT SEE PT V SCHEDULE L, PART III, LINE 1 GRANT PAID TO MIT TO FUND SCIENTIFIC RESEARCH CONDUCTED BY DR HOUSMAN'S LAB. X 5 158189 FMV 0 0 0 FORM 990, PAGE 1, BOX C IN 2025 HEREDITARY DISEASE FOUNDATION OFFICIALLY CHANGED THE NAME OF THE ORGANIZATION TO HUNTINGTON'S DISEASE FOUNDATION IN ORDER TO BRING THE NAME IN LINE WITH THE ORGANIZATION'S OVERALL MISSION AND PURPOSE. FORM 990, PART VI, SECTION A, LINE 2 NANCY WEXLER, PRESIDENT, AND ALICE WEXLER, SECRETARY, ARE SISTERS AND BOTH ARE MEMBERS OF THE BOARD OF DIRECTORS. MEGHAN DONALDSON, CEO, AND BRUCE DONALDSON, BOARD MEMBER, ARE MARRIED AND ARE BOTH MEMBERS OF THE BOARD OF DIRECTORS. FRANK GEHRY AND BERTA GEHRY WERE MARRIED AND BOTH WERE MEMBERS OF THE BOARD OF DIRECTORS. FRANK PASSED AWAY ON 12/5/25. SANDY FOX IS THE AUNT OF DAVID ZWALLY AND BOTH ARE MEMBERS OF THE BOARD OF DIRECTORS. TACIE FOX IS THE DAUGHTER OF SANDY FOX AND BOTH ARE MEMBERS OF THE BOARD OF DIRECTORS. THOMAS OBERSTEINER IS THE SON-IN LAW TO LAUREN PINKUS AND BOTH ARE MEMBERS OF THE BOARD OF DIRECTORS. FORM 990, PART VI, SECTION B, LINE 11B THE FOUNDATION PROVIDES THE 990 TO THE BOARD OF DIRECTORS FOR APPROVAL. FORM 990, PART VI, SECTION B, LINE 12C ANNUAL CONFLICT OF INTEREST STATEMENTS ARE CIRCULATED TO ALL OFFICERS, DIRECTORS, AND KEY EMPLOYEES AT THE BOARD OF DIRECTORS MEETING. MANAGEMENT MAINTAINS SIGNED COPIES OF THESE STATEMENTS FOR ALL SUCH INDIVIDUALS TO ENSURE COMPLIANCE WITH THIS POLICY. FORM 990, PART VI, SECTION B, LINE 15A A WRITTEN EMPLOYEE CONTRACT IS ESTABLISHED AND APPROVED BY THE BOARD OR COMPENSATION COMMITTEE. FORM 990, PART VI, SECTION C, LINE 19 THE FOUNDATION MAKES ITS FINANCIAL STATEMENTS AND 990 AVAILABLE TO THE PUBLIC ON ITS WEBSITE, WWW.HDFOUNDATION.ORG. THE FOUNDATION MAKES ITS GOVERNING DOCUMENTS AND CONFLICT OF INTEREST POLICY AVAILABLE TO THE PUBLIC UPON REQUEST.