2026-02-20T11:34:29-06:00 2025-06-30 WITHUMSMITHBROWN PC 1835 MARKET STREET SUITE 1710 PHILADELPHIA PA 191032945 990PF 2024-07-01 066034840 The Jane Coffin Childs Memorial Fund for Medical Research % THE FOUNDATION JANE 2037854612 333 Cedar Street SHM L300 New Haven CT 06510 BRONWEN A CHILDS DVM TREASURER 2037854612 2026-05-15 true true Israel Tannenbaum CPA P01589203 2155462140 2024 2025-03-06 01:10:19Z X 59956396 X 1215519 790760 790760 4400749 19012964 4400749 95000 6502028 5191509 0 503400 503400 164855 164855 14375 0 0 14375 24400 0 0 24400 119315 82058 0 37257 13747 0 0 0 49237 0 0 49237 416356 0 0 416356 1305685 82058 0 1209880 4461463 4071767 5767148 82058 0 5281647 734880 5109451 0 2794266 3977652 3977652 2773660 1458737 1458737 768000 478433 478433 47717 73850 73850 1049384 4587841 4587841 29652023 24180193 24180193 4664455 6564789 6564789 2704079 3410374 3410374 16201822 15224527 15224527 60655406 59956396 59956396 142011 100352 7318586 8241909 7460597 8342261 X 53194809 51614135 53194809 51614135 60655406 59956396 53194809 734880 53929689 2315554 51614135 SALE/MATURITY OF INVESTMENTS P 19012964 14612215 4400749 4400749 4400749 71021 71021 71021 0 0 0 1102 72123 false false false false false false false true true CT true false false false false true jccfund.org THE FOUNDATION 2037854612 333 CEDAR STREET SHM L300 NEW HAVEN CT 06510 false false false false false false false false false false false false false false true false false false false false false false John D Childs 333 Cedar Street SHM L300 New Haven CT 06510 Chairman 1.0 0 0 0 Bronwen A Childs D V M 333 Cedar Street SHM L300 New Haven CT 06510 Treasurer 1.0 0 0 0 John W Childs 333 Cedar Street SHM L300 New Haven CT 06510 Secretary 1.0 0 0 0 Robert Berman M D 333 Cedar Street SHM L300 New Haven CT 06510 Director 1.0 0 0 0 Vlad Coric M D 333 Cedar Street SHM L300 New Haven CT 06510 Director 1.0 0 0 0 Rebecca Ehrhardt 333 Cedar Street SHM L300 New Haven CT 06510 Director 1.0 0 0 0 Alexander Garside 333 Cedar Street SHM L300 New Haven CT 06510 Director 1.0 0 0 0 Dune Lawrence 333 Cedar Street SHM L300 New Haven CT 06510 Director 1.0 0 0 0 Avice Meehan 333 Cedar Street SHM L300 New Haven CT 06510 Director 1.0 0 0 0 Hendon C Pingeon 333 Cedar Street SHM L300 New Haven CT 06510 Director 1.0 0 0 0 Jon Rotolo 333 Cedar Street SHM L300 New Haven CT 06510 Director 1.0 0 0 0 Joan Steitz Ph D 333 Cedar Street SHM L300 New Haven CT 06510 Director 1.0 0 0 0 Maurie D McInnis Ph D 333 Cedar Street SHM L300 New Haven CT 06510 Ex-Officio 1.0 0 0 0 Fidelity 245 Summer Street BOSTON MA 02210 Investment Fees 82058 GRANTMAKING 4461463 CONVENING CONFERENCES 294158 41285508 1752307 0 43037815 0 43037815 645567 42392248 2119612 2119612 71021 71021 2048591 2048591 2048591 5281647 0 0 0 0 5281647 2048591 2022 2021 2020 1277574 987389 1022013 2319689 3309205 8915870 5281647 2048591 3233056 12148926 0 1277574 10871352 987389 1022013 2319689 3309205 3233056 ANITA PEPPER 333 CEDAR STREET SHM L300 NEW HAVEN CT 06510 2037854612 FORMAL WRITTEN APPLICATION OUTLINING PROPOSAL AND PREVIOUS WORK EXPERIENCE. FEBRUARY 1ST OF EACH YEAR. POST DOCTORAL FELLOWSHIPS FOR CANDIDATES WHO PERFORM CANCER RESEARCH. Boston Children's Hospital 300 Longwood Ave Boston MA 02115 NONE PC Dissecting the impact of non-coding somatic mutations in the human brain 37000 Boston Medical Center Corporation One Boston Medical Center Place Boston MA 02118 NONE PC Manipulating vascular endocytosis to direct blood and immune cell migration 74000 Brandeis University 415 South St Waltham MA 02453 NONE PC Timing molecular interactions in high throughput via a polymerase stopwatch 39000 Broad Institute of MIT and Harvard 415 Main St Cambridge MA 02142 NONE PC A DNA-encoded library strategy for molecular glue discovery 78000 Broad Institute of MIT and Harvard 415 Main St Cambridge MA 02142 NONE PC Deciphering the Molecular Mechanisms of Alternative Splicing Regulation via Intronic Transposable Elements 74000 California Institute of Technology 1200 E California Blvd Pasadena CA 91125 NONE PC Synthetic protein circuits a conditional triggers of anti-tumor immunity 107417 California Institute of Technology 1200 E California Blvd Pasadena CA 91125 NONE PC Defining the role of protein homeostasis in spermatogenesis 73800 Columbia University 116th and Broadway New York NY 10027 NONE PC Neuronal and immunological dissection of antidepresant responsiveness 106000 Columbia University 116th and Broadway New York NY 10027 NONE PC Learning the modular grammar of phase separation in signaling networks 76000 Dana Farber Cancer Institute 450 Brookline Ave Boston MA 02215 NONE PC Mechanisms and consequences of LINE-1-mediated genome instability 12333 Duke University 2080 Duke University Road Durham NC 27708 NONE PC Dissecting the Dynamics of Tissue Patterning During Regeneration 74000 Duke University 2080 Duke University Road Durham NC 27708 NONE PC Determining how basement membranes stretch and recover to support tissues 74000 Gladstone Institutes 1650 Owens Street San Francisco CA 94158 NONE PC The molecular biology of Obelisk RNAs 73800 Harvard University Massachusetts Hall Cambridge MA 02138 NONE PC How to build (and rebuild) an animal 74000 Harvard University Massachusetts Hall Cambridge MA 02138 NONE PC Reconstruct cell trajectories and communications in brain development 37000 Harvard University Massachusetts Hall Cambridge MA 02138 NONE PC The evolution of complex chemosensation 12333 Harvard University Massachusetts Hall Cambridge MA 02138 NONE PC Neural mechanisms of taste and visceral signal integration in the brainstem 37500 Harvard University Massachusetts Hall Cambridge MA 02138 NONE PC Molecular basis of sensory integration in octopus 74000 Harvard University Massachusetts Hall Cambridge MA 02138 NONE PC Secretory cell innovation in a symbiotic interaction 73800 Harvard University Massachusetts Hall Cambridge MA 02138 NONE PC Learning structure in genotype to phenotype maps 73800 Harvard University Medical School 25 Shattuck Street Boston MA 02115 NONE PC In Vivo tracking of G protein-coupled receptors sensing for gut metabolites 114000 Johns Hopkins University 733 N Broadway Baltimore MD 21205 NONE PC Defining regulatory principles of translation during nutrient shifts 30883 Johns Hopkins University School of Medicine 733 N Broadway Baltimore MD 21205 NONE PC Using single cell transcriptomics to understand homeostatic sleep pressure 74000 Massachusetts General Hospital 55 Fruit Street Boston MA 02114 NONE PC In situ cryoET analysis of cristae biogenesis and morphology 74000 Massachusetts Institute of Technology 77 Massachusetts Ave Cambridge MA 02139 NONE PC Central control of the autonomic nervous system in chronic pain and anxiety 74000 Massachusetts Institute of Technology 77 Massachusetts Ave Cambridge MA 02139 NONE PC LIGHTing up tumor-associated tertiary lymphoid structures through cytokine pharmacokinetic engineering 73800 Massachusetts Institute of Technology 77 Massachusetts Ave Cambridge MA 02139 NONE PC Understanding tissue damage in the pre-neoplasia to neoplasia shift of colorectal cancer 73800 Max Planck Institute of Immunobiology & Epigenetic Hofgartenstr 8 80539 Mnchen GM NONE PC Direct Visualization of DNA Methyltransferase Oligomerization and Its Influence on Neuronal Gene Regulation 74800 Memorial Sloan Kettering Cancer Center 1275 York Avenue New York NY 10065 NONE PC Mechanisms and consequences of APOBEC3 targeting of extrachromosomal DNA 73800 NIAID 5601 Fishers Lane Bethesda MD 20892 NONE PC Sexual recombination and virulence in the success of African trypanosomes 74000 National Institue of HealthNICHD 6 Center Drive Bethesda MD 20892 NONE PC Linking Parts to Process: Probing the Cell-Biological Basis for Tissue Patterning in Developing Mesenchyme 29167 Oregon Health and Science University 3181 SW Sam Jackson Park Road Portland OR 97239 NONE PC Mechanisms of Type I PARP1 Inhibitors in Regulating Cell Fate Decisions in Cancer 73800 Princeton University 70 WASHINGTON RD Princeton NJ 08544 NONE PC Main-Group Chemoproteomic Platforms for Deciphering and Drugging Methionine 106667 Princeton University 70 WASHINGTON RD Princeton NJ 08544 NONE PC Hormone-mediated changes in neural computations that drive flexible social behaviors 73800 Stanford University 450 Jane Stanford Way Stanford CA 94305 NONE PC Examining the neural mechanisms for generalization 113000 Stanford University 450 Jane Stanford Way Stanford CA 94305 NONE PC Decoding Aging Neurogenic Niches: Unraveling Somatic Mutations, Clonal Dynamics, and Functional Decline 73800 Stowers Institute for Medical Research 1000 E 50 Street Kansas City MO 64110 NONE PC Determine how ribosome heterogeneity regulates early embyrogenesis 76000 The Rockefeller University 1230 York Ave New York NY 10065 NONE PC Unraveling lipid transport across the mycobacterial cell envelope 76000 The Rockefeller University 1230 York Ave New York NY 10065 NONE PC Understanding how the whole becomes more than the sum of its parts: Linking subcellular processes to emergent supracellular patterns 44633 The Scripps Research Institute 10550 N Torrey Pines Road La Jolla CA 92037 NONE PC Timing biomolecular interactions in massively high throughput via a polymerase stopwatch 49333 The Scripps Research Institute 10550 N Torrey Pines Road La Jolla CA 92037 NONE PC Illuminating cryptic functional pockets in the human proteome with electrophilic stereoprobes 73800 The Scripps Research Institute 10550 N Torrey Pines Road La Jolla CA 92037 NONE PC Towards a novel tauopathy therapeutic: harnessing biomolecular condensates for targeted protein degradation 41800 The University of Texas at Austin 2515 Speedway Austin TX 78712 NONE PC Structure-based vaccine design targeting mpox antigen A27 73800 University of California Berkeley University Ave and Oxford St Berkeley CA 94720 NONE PC An unprecedented atomistic picture of contranslational protein folding 112000 University of California Berkeley University Ave and Oxford St Berkeley CA 94720 NONE PC Main-group platforms for deciphering and drugging metionine 4200 University of California Berkeley University Ave and Oxford St Berkeley CA 94720 NONE PC Exploring mechanisms for flexible learning in higher-order neural circuits 75000 University of California Berkeley University Ave and Oxford St Berkeley CA 94720 NONE PC Discovery and Synthesis of novel anticancer drugs via enzyme engineering 12334 University of California Berkeley University Ave and Oxford St Berkeley CA 94720 NONE PC Structural basis of Doa10-mediated protein quality control at the ER 75000 University of California San Francisco 513 Parnassus Ave San Francisco CA 94143 NONE PC Ovulation of the fittest 106000 University of California San Francisco 513 Parnassus Ave San Francisco CA 94143 NONE PC Uncovering the functional architecture of the human speech cortex 78000 University of California San Francisco 513 Parnassus Ave San Francisco CA 94143 NONE PC Evolution of human-specific neuronal activity-dependent gene regulation 106000 University of Michigan 500 S State St Ann Arbor MI 48109 NONE PC Interplay of spatial structure and collective drug resistance across scale 57500 University of Minnesota 100 Church Street SE Mineapolis MN 55455 NONE PC Effects of regulatory network divergence on drug resistance in Candida 74000 University of Utah 201 Presidents Circle Salt Lake City UT 84112 NONE PC Classification of exotic ATPase functions using large language models 74000 University of Utah 201 Presidents Circle Salt Lake City UT 84112 NONE PC Ron Tyrosine Kinase deficiency uncovers a critical regulator of anti-tumor T Cell responses 73800 University of Washington 1410 NE Campus Parkway Seattle WA 98195 NONE PC Evaluating neuromodulatory networks across brain states 112667 University of Washington 1410 NE Campus Parkway Seattle WA 98195 NONE PC Mechanisms of Immune Memory Generation in a Native RNA Targeting CRISPR System 113000 Yale University PO Box 208327 New Haven CT 06520 NONE PC Novel Chemical Tools for Targeted Eradication of DNA Repair Proteins and Application to Chemosensitization 73800 4071767 Cincinnati Children's Hospital 3333 Burnet Avenue Cincinnati OH 45229 none PC Multifunctional RNA-binding transcription factors coordinate cell states in development 0 Gladstone Institutes 1650 Owens Street San Francisco CA 94158 none PC Engineering CAR T cells for Enhanced Cancer Immunotherapy via Protein Interaction Network Analysis 0 Harvard Medical School 25 Shattuck Street Boston MA 02115 none PC Organisational logic of the spino-parabrachial pathway for light touch 0 Massachusetts General Hospital 55 Fruit Street Boston MA 02114 none PC A spatial stochasticity theory resolves how host-protective T cell responses emerge amid regulatory T cell immunosuppression 0 Massachusetts Institute of Technology 77 Massachusetts Ave Cambridge MA 02139 none PC Illuminating the cell envelope architecture and assembly of a tick-borne pathogen 0 Massachusetts Institute of Technology 77 Massachusetts Ave Cambridge MA 02139 none PC Role of neoantigen-nonspecific Passenger T cells in cancer-associated immunity and tumor progression 0 Memorial Sloan Kettering Cancer Center 1275 York Avenue New York NY 10065 none PC Understanding how bacteria-bacteria interactions influence antibiotic resistance in a microbiome context 0 Memorial Sloan Kettering Cancer Center 1275 York Avenue New York NY 10065 none PC Recording cell states and signaling events to reveal cell fate decisions during pancreatic islet differentiation 0 Princeton University 70 WASHINGTON RD Princeton NJ 08544 none PC Biochemical basis and function of lipid spatial localization within the brain 0 Stanford University 450 Jane Stanford Way Stanford CA 94305 none PC Deciphering the Role of EBV-Infected B Cells and Autoimmunity in Post-Infectious Syndromes and Developing a Targeted Elimination Strategy 0 The Rockefeller University 1230 York Ave New York NY 10065 none PC A genetic approach to study metabolite sensing and regulation in organelles 0 University of California San Francisco 513 Parnassus Ave San Francisco CA 94143 none PC Neuronal mechanisms of simulations in the brain of sleeping mice 0 University of California Berkeley University Ave and Oxford St Berkeley CA 94720 none PC Harnessing long-range hormone signaling for therapeutic delivery 0 University of Colorado Boulder 3100 Marine St Boulder CO 80303 none PC Unlocking the Bacterial Vault: Novel Organelles Involved in RNA Repair 0 University of Utah 201 Presidents Circle Salt Lake City UT 84112 none PC The early-life microbiome regulates BETA-cell function and type-1 diabetes via gamma-aminobutyric acid 0 University of Washington 1410 NE Campus Parkway Seattle WA 98195 none PC "Healthy aneuploidy": Discovering strategies from the placenta to regulate aneuploidy tolerance 0 University of Washington 1410 NE Campus Parkway Seattle WA 98195 none PC Investigation of immune systems in multicellular bacteria 0 University of Washington 1410 NE Campus Parkway Seattle WA 98195 none PC Decoding the Structural Basis of Immunogenicity 0 Vanderbilt University Medical Center 1211 Medical Center Drive Nashville TN 37232 none PC Defining the targets of the antibody response to natural Oropouche virus infection 0 Washington University in St Louis 1 Brookings Drive St Louis MO 63130 none PC Structural mechanisms for higher-order microtubule assembly function in parasites 0 Washington University in St Louis 1 Brookings Drive St Louis MO 63130 none PC The functional role of transposable element-derived transcripts in cancer progression 0 4458200 14 790760 18 4400749 MANAGEMENT FEES 01 95000 5286509 5286509 false false false false false false false false false false X X 1 John W Childs 333 Cedar Street SHM L300 New Haven CT 06510 200000 X 2 MERCK SHARP DOHME LLC 126 East Lincoln Ave PO Box200 Rahway NJ 07065 399200 X 3 Select Equity Group 380 Lafayette Street New York NY 10003 96894 X 4 Richard Cross 333 Cedar Street SHM L300 New Haven CT 06510 70000 X 5 Robert Berman 333 Cedar Street SHM L300 New Haven CT 06510 50000 X 6 Johnson Johnson 200 Wingo Way Mount Pleasant SC 29464 30000 X 7 THE COMMUNITY FDN FOR GREATER NEW 70 Audubon Street New Haven CT 06510 27464 X 8 Howard Hughes Medical Institute 4000 Jones Bridge Road Chevy Chase MD 208156789 25000 X 9 John D Childs 333 Cedar Street SHM L300 New Haven CT 06510 20000 X 10 James Hagy 333 Cedar Street SHM L300 New Haven CT 06510 10000 X 11 Jon Rotolo 333 Cedar Street SHM L300 New Haven CT 06510 10000 X ACCOUNTING FEES 24400 0 0 24400 Fidelity Investment Management Fees CORPORATE BONDS 6564789 6564789 COMMON STOCKS 19529882 19529882 EQUITY EXCHANGE TRADED FUNDS 3815598 3815598 EQUITY MUTUAL FUNDS 834713 834713 4587841 4587841 PRIVATE EQUITY AT COST 3410374 3410374 LEGAL FEES 14375 0 0 14375 CHARITABLE REMAINDER UNITRUST 16142830 15104453 15104453 ACCRUED INTEREST 47155 104690 104690 DUE FROM CAC 11837 15384 15384 UNREALIZED LOSS 1277177 CHARITABLE REMAINDER UNITRUST 1038377 VENUE, FOOD AND BEVERAGE 245158 0 0 245158 OFFICE EXPENSE 120323 0 0 120323 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