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        <ReturnReference>Schedule J, Part III</ReturnReference>
        <Explanation>First class and business class fares for domestic travel, Canada, the Caribbean, Central America, and Mexico are not reimbursable. However, personal frequent flier mileage and/or coupons may be used for no-cost upgrades. Only the CEO and Founder are approved for first class travel. Whenever possible discounted first class and upgrades are used to minimize cost. Schedule J, Part I, Line 4A Severance payments were made to the following during calendar year 2010: Annette Hewko, Kimberly Earle, Hala Moddelmog, and Marianna Alciati. Schedule J, Part I, Line 6A The SMARTpay Incentive Plan is designed to drive organizational performance, enhance the organizations competitive pay position and positively affect our ability to attract and retain talent. Currently, annual operational financial performance at Headquarters must provide full funding of the board approved budgeted slate of research grants and mission activity while ensuring adjusted net operating activity remains at breakeven. This SMARTpay Incentive Plan is an annual program, giving full discretion to the organizations Board of Directors for renewal, suspension, or termination of the plan. The SmartPay Incentive plan is available to all employees of the Parent. No amounts were paid for calendar year 2010. Schedule J, Part J-2 Jennifer Luray was an officer of the Susan G. Komen Breast Cancer Foundation, Inc. 100% of her compensation is being reported on Susan G. Komen for the Cure Advocacy Alliance's form 990, Part VII and Schedule J.</Explanation>
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        <Identifier>Volunteers</Identifier>
        <ReturnReference>Form 990, Part I, Question 6</ReturnReference>
        <Explanation>Volunteers serve in a variety of ways but the greatest number of volunteers assist with the Breast Cancer 3 Day series.</Explanation>
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        <Identifier>Program Service Accomplishments</Identifier>
        <ReturnReference>Part III</ReturnReference>
        <Explanation>Nancy G. Brinker promised her dying sister, Susan G. Komen, that she would do everything in her power to end breast cancer forever. In 1982, that promise became Susan G. Komen for the Cure (Komen) and launched the global breast cancer movement. Today, Komen for the Cure is the world's largest grassroots network of breast cancer survivors and activists fighting to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Komen Race for the Cure, Komen has invested nearly $2 billion to fulfill its promise, becoming the largest source of nonprofit funds dedicated to the fight against breast cancer in the world. A - Research and Training Komen has touched virtually every major advance in breast cancer research over the past 30 years. By funding the best scientists around the world, Komen is speeding the translation of research discoveries to reduce breast cancer incidence and mortality within the next decade. To ensure maximum impact for its research dollars, Komen for the Cure is guided by a Scientific Advisory Board, a group of internationally recognized doctors, scientists and advocates, and the consultation of the Komen Scholars, almost 70 scientists and advocates. Komen made 183 grants in fiscal year 2011 through the granting programs, described below, to support research and training in 26 US states and other countries including Australia, Belgium, Canada, England, Israel, Italy, and Switzerland. Komen supports research and training through several different types of grants, each designed to meet specific objectives. The following grant opportunities were offered by Komen during fiscal year 2011: - Promise Grants: Large-scale grants, up to $6.5 million each, during a five-year period, targeted to research that brings science to the bedside quicker than ever before. - Post-Doctoral Fellowships: Grants of $60,000 per year for two or three years to attract and retain promising young researchers. - Career Catalyst Research: Grants of $150,000 per year for two to three years to fill a critical gap in support and stimulate the transition from training to independence among promising cancer investigators. - Investigator Initiated Research: Grants of up to $200,000 per year for two to three years to explore new ideas and approaches with significant potential to lead to reductions in breast cancer mortality and/or incidence within the decade. - Post Baccalaureate in Disparities Research: Grants up to $135,000 per year over three years to support training programs for graduate students in the area of breast cancer disparities. Approximately 40% of these grants are exploring the biology of breast cancer, including how cancer starts, grows and spreads. The next largest group of grants (20%) is for research on new and improved ways to detect cancer earlier. Almost 15% are supporting research into new breast cancer treatments, with several focusing on especially aggressive forms of the disease such as triple negative breast cancer. Another 15% of the grants are specifically looking for ways to prevent breast cancer. Below are three examples of promising research grants funded in fiscal year 2011: Researchers at Washington University School of Medicine in St. Louis are working to develop personalized breast cancer DNA vaccines, targeting unique tumor antigens identified by sequencing patients' genomes (DNA). The vaccines are being tested as a way to prevent breast cancer recurrence, but in the future may be given in conjunction with chemotherapy and radiation, or even in place of those treatments. A personalized cancer vaccine strategy is potentially applicable to all breast cancer patients, regardless of the subtype (e.g., triple negative, ER+, HER2+), and likely could be applied to other types of cancer as well. University of Michigan researchers have teamed up to develop novel therapies for triple negative breast cancer (TNBC) by targeting cancer stem cells (CSCs), which are resistant to radiation and chemotherapy and are highly invasive. Cancer stems cells are more abundant in TNBC and may also be more frequent in Black African and African-American women, which may account for the aggressive nature of TNBC and contribute to racial disparities in outcomes. About 5% to 10% of breast cancer cases are thought to be hereditary, resulting directly from gene defects (mutations) inherited from a parent. The known mutations are very rare in the population, but their effect on breast cancer risk is very strong. A research team at New York University is working to discover these genetic mutations, leading to more reliable identification of individuals at high-risk for breast cancer, and better therapies targeted against the mutations. Komen also supported dozens of partnerships and special projects to advance research and our understanding of breast cancer around the world. These grants respond to unique opportunities, leverage the work of different organizations, and address critical challenges and cross-cutting issues in research, clinical practice, and public health. Examples of special research efforts committed in fiscal year 2011 include the following: American Association for Cancer Research (AACR) - Komen has partnered with AACR to bring a variety of programming to the breast cancer research community, including researchers and advocates. In fiscal year 2011 alone, Komen awarded $1M to the AACR in support of five major scientific conferences - on topics ranging from molecular diagnostics to the science of health disparities -- and for the Scientist-Survivor Program. Workshop on Systems Toxicology Analysis of Targeted Anti-Cancer Therapies - The Reagan-Udall Foundation for the FDA and Friends of Cancer Research convened experts from academia, government, and industry to study the cardio-toxic effects of a class of anti-cancer drugs called tyrosine kinase inhibitors (TKIs). The goal is to use this knowledge about the signaling pathways leading to these side effects to develop biomarkers that could help identify patients with favorable risk/benefit profiles, or consider approaches to prevention of toxicity. The Institute of Medicine (IOM) Breast Cancer and the Environment Project - With widely divergent opinions within the scientific community on the role of chemicals, the environment and lifestyle in cancer development, Komen is working with the IOM for a second year to review and assess the strength of the science regarding possible links between breast cancer and the environment. The IOM will publish its findings and recommendations in a technical report and accompanying lay summary. B - Education Komen is a trusted source of breast health and breast cancer information for people all over the world and is instrumental in connecting people with the resources they need in their fight against breast cancer. Our award-winning website, www.komen.org, provides safe, accurate, comprehensive, and unbiased information about breast cancer based upon scientific evidence, as well as information about our research programs, community programs, volunteer opportunities, and events. The "Understanding Breast Cancer" section of the website, co-developed with Harvard Medical School, received over 2.4 million visits during fiscal year 2011. Komen also produces science-based, easy-to-read educational materials. Nearly 6.5 million educational materials were distributed in fiscal year 2011. Examples of Komen educational materials include the following: - Breast Self-Awareness cards in 18 languages for 20 specific audiences - General breast health awareness and breast cancer specific brochures and fact sheets - Booklets with support information for survivors and co-survivors Komen's trained and caring breast care helpline staff (1-877 GO KOMEN) provide answers to questions, local resources and moral support. Last fiscal year, the Susan G. Komen for the Cure breast cancer helpline responded to nearly 14,000 calls. While African American women are less likely to be diagnosed with breast cancer than Caucasian women, they are more likely to die from the disease. Susan G. Komen for the Cure Circle of Promise further engages African American women, and black women around the world, in the fight against breast cancer. At the end of fiscal year 2011, a total of 100,000 ambassadors had been recruited to do the following: - Mobilize the community to ensure that women everywhere have access to the care they need - Empower women to make a promise to reclaim their lives, their health and to be strong advocates in their communities - Dispel myths in the African American community that prevent women from getting early treatment for breast cancer</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Program Service Accomplishments Continued</Identifier>
        <ReturnReference>Part III</ReturnReference>
        <Explanation>I AM THE CURE is an educational program that teaches simple, action-oriented, breast health information to participants in the Susan G. Komen Race for the Cure series. Last year, nearly 1.7 million people participated in a Race for the Cure event. A formal evaluation showed that 82% of participants recalled the message that early detection is key to survival. The mobile community education and outreach tour, Komen On the Go, shares important information about breast cancer with all generations. This nationwide initiative is a fun, hands-on learning experience that engages people at community locations such as health fairs, shopping malls, churches, colleges and university campuses. Last year, the Komen On the Go vehicles were in more than 40 communities and reached 30,000 people with educational messages. Cancer kills more people, worldwide, than TB, HIV/AIDS and Malaria combined. Komen is waging the global fight against breast cancer by building and strengthening grassroots programs through networking, training, capacity building and financial support. In fiscal year 2011, 244 breast cancer advocates in six countries (Brazil, Egypt, Mexico, Panama, Romania, and Ukraine) were trained through the Course for the Cure, which is the cornerstone of the Komen's Global Initiative for Breast Cancer Awareness. Course for the Cure is a series of easily adaptable training modules that are based on Komen's best practices and experience in breast cancer awareness and advocacy. Additionally, Komen awarded grants for outreach programs in Bosnia and Herzegovina, Colombia, Costa Rica, Egypt, Ghana, Hungary, Israel, Kenya, Montenegro, Panama, Romania, Russia, and Ukraine and conferences in Brazil and Egypt. C - Screening Getting regular screening tests is the best way for women to lower their risk of dying from breast cancer. Screening tests can find breast cancer early, when it's most treatable. Komen supports free and low-cost mammogram programs in communities for women without health insurance or those with high co-pays and deductibles that make getting a mammogram too costly. D - Treatment Countless numbers of patients delay or forgo breast cancer treatment each year and as a result, these women are less likely to survive. For this reason, Komen supports programs that connect people with local resources, provide emergency financial assistance, and help coordinate care. Komen also supports two national patient assistance programs. One grant was awarded to the national cancer support organization, CancerCare, to support the Linking A.R.M.S. program. The program provides direct financial assistance to approximately 1,200 women for treatment-related expenses for including pain and anti-nausea medication, lymphedema care, oral chemotherapy, and durable medical equipment. CancerCare also provides counseling and other support services that enable breast cancer patients to make informed treatment decisions, cope with the emotional effects of the disease, and experience an improved quality of life. In addition, Komen made a $2 million grant to the Patient Advocate Foundation, a national non-profit organization that handles medical debt crisis management. The grant will provide pharmaceutical co-payment help to more than 850 breast cancer patients nationwide and will also allow PAF to directly reach out to African American and Hispanic/Latina breast cancer patients, increasing awareness about resources available to them. All told, Komen has committed more than $1.3 billion to community programs since 1982, and in FY 2011 partnered with almost 2,000 organizations to provide education, screening, treatment support and psychosocial programs. For more information about any of the accomplishments described here or to learn more about Susan G. Komen for the Cure, visit www.komen.org or call 1-877 GO KOMEN. Description of Relationships Form 990, Part VI, Question 2 Eric Brinker, Board Member, is the son of Nancy G. Brinker, CEO and Board member. Describe the Process used by Management &amp;/or Governing Body to Review 990 Form 990, Part VI, Question 11b Management prepares the materials for the Form 990, with the assistance and review by external accountants. Senior levels of management review and comment on the final draft of the Form 990 for presentation to the audit committee of the board of directors. The audit committee of the Board of the Directors reviews and approves the Form 990 prior to being filed. Thereafter, each member of the Board of Directors receives an electronic copy of the Form 990 via email prior to the form being filed. Description of Process to Monitor Transactions for Conflicts of Interest Form 990, Part VI, Question 12c The organization produces an annual survey requiring all employees, board members, committee members and advisory boards to inform on conflicts. Any conflicts are then reviewed by management and the audit committee and appropriate measures are taken. In addition, those same people have the obligation to update the conflict of interest statements during the year.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Offices &amp; Positions for Which Process was Used, &amp; Year Process was Begun</Identifier>
        <ReturnReference>Form 990, Part VI, Question 15a and 15b</ReturnReference>
        <Explanation>The Compensation Committee of the Board of Directors assists the Board of Susan G. Komen for the Cure in overseeing compensation policies and practices. Responsibilities include oversight of the compensation of the President/ Chief Executive Officer, the range of compensation levels for the organizations other officers, disqualified persons, and other employees, granting the CEO authority to determine actual compensation levels within an approved range, and incentive/bonus compensation programs. The current policy was adopted in 2010. A formal Compensation Policy governs pay practices. Periodically, all positions in the organization are reviewed against external market data, engaging independent experts to conduct the benchmarking process. Compensation is then based upon comparable market rates of pay with consideration for internal equity and the financial position of the organization. The process was last conducted this fiscal year. Salary increases, promotions or other forms of compensation are provided without regard to race, color, religion, gender, national origin, disability, veteran status or sexual orientation.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Avail of Gov Docs, Conflict of Interest Policy, &amp; Fin Stmts to Gen Public</Identifier>
        <ReturnReference>Form 990, Part VI, Question 19</ReturnReference>
        <Explanation>The Organizations financial statements, conflict of interest policy and the 990 are publicly available on our website. The Articles of Incorporation are available from the Texas Secretary of State and other governing documents are made available as required by state law. Form 1023 is not online but available to the public upon request. ADDITIONAL DETAIL ON RACE PRODUCTION EXPENSES INCLUDED ON OTHER EXP LINE Form 990, Part IX, Line 24 THE SUSAN G. KOMEN BREAST CANCER FOUNDATION, INC. PURCHASES ALL T-SHIRTS FOR THE 100 PLUS RACES HELD BY THE KOMEN AFFILIATES DURING THE YEAR. Other changes in Net Assets Part XI Reconciliation of Net Assets Unrealized gains on investments = $11,234,103 In Kind services Revenues = $20,645,021 In Kind services expenses =($21,593,231) Rescinded Grants = $954,975 Rounding = ($4) ------------- Total $11,240,864</Explanation>
      </GeneralExplanation>
    </IRS990ScheduleO>
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