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      <ReconcilationRevenueExpenses>-8912510</ReconcilationRevenueExpenses>
      <MethodOfAccountingAccrual>X</MethodOfAccountingAccrual>
      <AccountantCompileOrReview>false</AccountantCompileOrReview>
      <FSAudited>true</FSAudited>
      <AuditCommittee>true</AuditCommittee>
      <FinancialStatementSeparate>X</FinancialStatementSeparate>
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        <CurrentTaxYear>77455</CurrentTaxYear>
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      <TotalSupport>87710442</TotalSupport>
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      <EndowmentsHeldByRelatedOrgs>false</EndowmentsHeldByRelatedOrgs>
      <AreRelatedOrgsListedScheduleR>false</AreRelatedOrgsListedScheduleR>
      <LeaseholdImprovements>
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        <Depreciation>118086</Depreciation>
        <BookValue>162342</BookValue>
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      <Equipment>
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        <Depreciation>610546</Depreciation>
        <BookValue>52491</BookValue>
      </Equipment>
      <TotalOfBookValueLandBuildings>214833</TotalOfBookValueLandBuildings>
      <Form990ScheduleDPartXIV>
        <Identifier>LIABILITY UNDER FIN 48 FOOTNOTE</Identifier>
        <ReturnReference>SCHEDULE D, PAGE 3, PART X</ReturnReference>
        <Explanation>THE ORGANIZATION HAS EVALUATED ITS TAX POSITIONS TAKEN FOR ALL OPEN TAX YEARS AND HAS NOT IDENTIFIED ANY UNCERTAIN TAX POSITIONS WHICH WOULD REQUIRE DISCLOSURE IN THE CONSOLIDATED FINANCIAL STATEMENTS. CURRENTLY, THE ORGANIZATION IS NO LONGER SUBJECT TO EXAMINATION BY THE INTERNAL REVENUE SERVICE (IRS) FOR YEARS BEFORE 2007. THE ORGANIZATION IS NOT CURRENTLY UNDER AUDIT NOR HAS THE ORGANIZATION BEEN CONTACTED BY THE IRS.</Explanation>
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    <IRS990ScheduleI documentId="RetDoc6">
      <RecordsMaintained>true</RecordsMaintained>
      <RecipientTable>
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          <BusinessNameLine1>JAEB CENTER RESEARCH TRUST</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>15310 AMBERLY DRIVE SUITE 350</AddressLine1>
          <City>TAMPA</City>
          <State>FL</State>
          <ZIPCode>33647</ZIPCode>
        </AddressUS>
        <EINOfRecipient>270717710</EINOfRecipient>
        <IRCSection>501</IRCSection>
        <AmountOfCashGrant>7303579</AmountOfCashGrant>
        <PurposeOfGrant>SUPPORT</PurposeOfGrant>
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      <Form990ScheduleIPartIV>
        <Identifier>PROCEDURES FOR MONITORING THE USE OF GRANT FUNDS INSIDE THE UNITED STATES</Identifier>
        <ReturnReference>SCHEDULE I, PAGE 1, PART I, LINE 2</ReturnReference>
        <Explanation>THE ORGANIZATION GIVES GRANTS TO THEIR RELATED NON-PROFIT ORGANIZATION TO INVEST. WHEN FUNDS ARE GIVEN BACK TO JAEB CENTER FOR HEALTH RESEARCH, INC., THEY ARE USED BY THE ORGANIZATION IN THEIR EXEMPT PURPOSE.</Explanation>
      </Form990ScheduleIPartIV>
    </IRS990ScheduleI>
    <IRS990ScheduleJ documentId="RetDoc7">
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      <IndependentConsultant>X</IndependentConsultant>
      <BoardOrCommitteeApproval>X</BoardOrCommitteeApproval>
      <SeverancePayment>false</SeverancePayment>
      <SupplementalNonqualRetirePlan>false</SupplementalNonqualRetirePlan>
      <EquityBasedCompArrangement>false</EquityBasedCompArrangement>
      <CompBasedOnRevenueOfFilingOrg>false</CompBasedOnRevenueOfFilingOrg>
      <CompBasedOnRevenueRelatedOrgs>false</CompBasedOnRevenueRelatedOrgs>
      <CompBasedNetEarningsFilingOrg>false</CompBasedNetEarningsFilingOrg>
      <CompBasedNetEarningsRelateOrgs>false</CompBasedNetEarningsRelateOrgs>
      <AnyNonFixedPayments>false</AnyNonFixedPayments>
      <InitialContractException>false</InitialContractException>
      <Form990ScheduleJPartII>
        <NamePerson>ROY W BECK MD PHD</NamePerson>
        <BaseCompensationFilingOrg>373000</BaseCompensationFilingOrg>
        <NontaxableBenefitsFilingOrg>92877</NontaxableBenefitsFilingOrg>
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      <Form990ScheduleJPartII>
        <NamePerson>CRAIG KOLLMAN</NamePerson>
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        <TotalCompensationFilingOrg>200443</TotalCompensationFilingOrg>
        <CompReportPrior990FilingOrg>172362</CompReportPrior990FilingOrg>
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      <Form990ScheduleJPartII>
        <NamePerson>PAMELA MOKE</NamePerson>
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        <NontaxableBenefitsFilingOrg>40645</NontaxableBenefitsFilingOrg>
        <TotalCompensationFilingOrg>197575</TotalCompensationFilingOrg>
        <CompReportPrior990FilingOrg>163619</CompReportPrior990FilingOrg>
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      <Form990ScheduleJPartII>
        <NamePerson>B MICHELLE MELIA</NamePerson>
        <BaseCompensationFilingOrg>140100</BaseCompensationFilingOrg>
        <NontaxableBenefitsFilingOrg>36286</NontaxableBenefitsFilingOrg>
        <TotalCompensationFilingOrg>176386</TotalCompensationFilingOrg>
        <CompReportPrior990FilingOrg>137763</CompReportPrior990FilingOrg>
      </Form990ScheduleJPartII>
      <Form990ScheduleJPartII>
        <NamePerson>JAMES PYNER</NamePerson>
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        <NontaxableBenefitsFilingOrg>31063</NontaxableBenefitsFilingOrg>
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    <IRS990ScheduleL documentId="RetDoc8">
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        <NamePerson>ROY W BECK</NamePerson>
        <PurposeOfLoan>WORKING CAPITAL</PurposeOfLoan>
        <LoanToOrganization>X</LoanToOrganization>
        <OriginalPrincipalAmount>59500</OriginalPrincipalAmount>
        <BalanceDue>59500</BalanceDue>
        <Default>false</Default>
        <ApprovedByBoard>true</ApprovedByBoard>
        <WrittenAgreement>true</WrittenAgreement>
      </LoanTable>
      <TotalBalanceDue>59500</TotalBalanceDue>
    </IRS990ScheduleL>
    <IRS990ScheduleN documentId="RetDoc9">
      <DispositionTable>
        <DescriptionOfAsset>GRANT</DescriptionOfAsset>
        <DateOfDistribution>2010-07-08</DateOfDistribution>
        <FMVOfAsset>7303579</FMVOfAsset>
        <MethodOfFMVDetermination>CASH</MethodOfFMVDetermination>
        <EIN>270717710</EIN>
        <NamePerson>JAEB CENTER RESEARCH TRUST INC</NamePerson>
        <AddressUS>
          <AddressLine1>15310 AMBERLY DRIVE SUITE 350</AddressLine1>
          <City>TAMPA</City>
          <State>FL</State>
          <ZIPCode>33647</ZIPCode>
        </AddressUS>
        <IRCSection>501C3</IRCSection>
      </DispositionTable>
      <DirectorOfSuccessor2>false</DirectorOfSuccessor2>
      <EmployeeOfSuccessor2>false</EmployeeOfSuccessor2>
      <OwnerOfSuccessor2>false</OwnerOfSuccessor2>
      <ReceiveCompensation2>false</ReceiveCompensation2>
      <Form990ScheduleNPartIII>
        <Identifier>ADDITIONAL INFORMATION</Identifier>
        <ReturnReference>SCHEDULE N</ReturnReference>
        <Explanation>THE ORGANIZATION GIVES GRANTS TO THEIR RELATED NONPROFIT ORGANIZATION TO INVEST WHEN FUNDS ARE GIVEN BACK TO JAEB CENTER FOR HEALTH RESEARCH INC THEY ARE USED BY THE ORGANIZATION FOR THEIR EXEMPT PURPOSE</Explanation>
      </Form990ScheduleNPartIII>
    </IRS990ScheduleN>
    <IRS990ScheduleO documentId="RetDoc10">
      <GeneralExplanation>
        <Identifier>ORGANIZATION'S MISSION</Identifier>
        <ReturnReference>FORM 990 - ORGANIZATION'S MISSION</ReturnReference>
        <Explanation>DEVELOP, DESIGN AND COORDINATE CLINICAL TRIALS IN OPHTHALMOLOGY AND DIABETES INCLUDING FUNCTIONING AS THE COORDINATING CENTER FOR THOSE TRIALS AND CONDUCTING THE STATISTICAL ANALYSIS AND PREPARATION OF MANUSCRIPTS AND OTHER PUBLICATIONS RESULTING FROM THOSE TRIALS</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>ORGANIZATION'S PROCESS USED TO REVIEW FORM 990</Identifier>
        <ReturnReference>FORM 990, PAGE 6, PART VI, LINE 11B</ReturnReference>
        <Explanation>THE BOARD OF DIRECTORS RECEIVE FORM 990 VIA E-MAIL AND ARE INVITED TO PROVIDE QUESTIONS, COMMENTS, AND SUGGESTIONS PRIOR TO THE FORM'S FILING.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>ENFORCEMENT OF CONFLICTS POLICY</Identifier>
        <ReturnReference>FORM 990, PAGE 6, PART VI, LINE 12C</ReturnReference>
        <Explanation>CONFLICT OF INTEREST FORMS ARE REQUESTED EVERY YEAR AND REVIEWED BY PROJECT CHAIRPERSON FOR INVESTIGATORS/COORDINATORS ETC., BY COMPLIANCE OFFICER AND IRB CHAIR FOR INVESTIGATORS THAT ARE COVERED BY JAEB IRB AND BY HR DIRECTOR FOR JAEB CENTER FOR HEALTH RESEARCH, INC. EMPLOYEES NOT COVERED BY JAEB IRB.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>COMPENSATION PROCESS FOR TOP OFFICIAL</Identifier>
        <ReturnReference>FORM 990, PAGE 6, PART VI, LINE 15A</ReturnReference>
        <Explanation>SALARY OF EXECUTIVE DIRECTOR IS BASED ON A STUDY PERFORMED BY AN INDEPENDENT COMPENSATION CONSULTANT AND REVIEWED ANNUALLY BY THE SALARY SUB-COMMITTEE OF THE BOARD. INCREASES ARE HELD AT 3% PER YEAR.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>COMPENSATION PROCESS FOR OFFICERS</Identifier>
        <ReturnReference>FORM 990, PAGE 6, PART VI, LINE 15B</ReturnReference>
        <Explanation>ALL OTHER SALARIES ARE REVIEWED BY EXECUTIVE DIRECTOR IN CONJUNCTION WITH WRITTEN ANNUAL PERFORMANCE REVIEW.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>GOVERNING DOCUMENTS DISCLOSURE EXPLANATION</Identifier>
        <ReturnReference>FORM 990, PAGE 6, PART VI, LINE 19</ReturnReference>
        <Explanation>ANY MEMBER OF THE PUBLIC CAN COME IN AND INSPECT THE PUBLICLY AVAILABLE PORTIONS OF OUR GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY, AND FINANCIAL STATEMENTS IN OUR OFFICE DURING REGULAR OFFICE HOURS.</Explanation>
      </GeneralExplanation>
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        <AddressUS>
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          <City>TAMPA</City>
          <State>FL</State>
          <ZIPCode>33647</ZIPCode>
        </AddressUS>
        <EIN>270717710</EIN>
        <PrimaryActivities>SUPPORT</PrimaryActivities>
        <LegalDomicileState>FL</LegalDomicileState>
        <ExemptCodeSection>501C3</ExemptCodeSection>
        <PublicCharityStatus>11B</PublicCharityStatus>
        <DirectControllingEntityNA>N/A</DirectControllingEntityNA>
        <ControlledOrg>false</ControlledOrg>
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      <GiftGrantOrCapContrFrOtherOrg>false</GiftGrantOrCapContrFrOtherOrg>
      <LoansOrGuaranteesToOtherOrg>false</LoansOrGuaranteesToOtherOrg>
      <LoansOrGuaranteesFromOtherOrg>false</LoansOrGuaranteesFromOtherOrg>
      <SaleOfAssetsToOtherOrg>false</SaleOfAssetsToOtherOrg>
      <PurchaseOfAssetsFromOtherOrg>false</PurchaseOfAssetsFromOtherOrg>
      <ExchangeOfAssets>false</ExchangeOfAssets>
      <RentalOfFacilitiesToOtherOrgs>false</RentalOfFacilitiesToOtherOrgs>
      <RentalOfFacilitiesFrOtherOrgs>false</RentalOfFacilitiesFrOtherOrgs>
      <PerformOfServicesForOtherOrgs>false</PerformOfServicesForOtherOrgs>
      <PerformOfServicesByOtherOrgs>false</PerformOfServicesByOtherOrgs>
      <SharingOfFacilities>true</SharingOfFacilities>
      <SharingOfPaidEmployees>true</SharingOfPaidEmployees>
      <ReimbursementPaidToOtherOrg>false</ReimbursementPaidToOtherOrg>
      <ReimbursementPaidByOtherOrg>false</ReimbursementPaidByOtherOrg>
      <OtherTransferToOtherOrg>false</OtherTransferToOtherOrg>
      <OtherTransferFromOtherOrg>false</OtherTransferFromOtherOrg>
      <TransactionsRelatedOrgsTable>
        <NameOfOtherOrganization>
          <BusinessNameLine1>JAEB CENTER RESEARCH TRUST INC</BusinessNameLine1>
        </NameOfOtherOrganization>
        <TransactionType>B</TransactionType>
        <AmountInvolved>7303579</AmountInvolved>
        <MethodOfAmtDetermination>CASH</MethodOfAmtDetermination>
      </TransactionsRelatedOrgsTable>
      <TransactionsRelatedOrgsTable>
        <NameOfOtherOrganization>
          <BusinessNameLine1>JAEB CENTER RESEARCH TRUST INC</BusinessNameLine1>
        </NameOfOtherOrganization>
        <TransactionType>M</TransactionType>
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      <TransactionsRelatedOrgsTable>
        <NameOfOtherOrganization>
          <BusinessNameLine1>JAEB CENTER RESEARCH TRUST INC</BusinessNameLine1>
        </NameOfOtherOrganization>
        <TransactionType>N</TransactionType>
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      <Form990ScheduleRPartVII>
        <Identifier>ADDITIONAL INFORMATION</Identifier>
        <ReturnReference>SCHEDULE R</ReturnReference>
        <Explanation>SCHEDULE R PART V LINE 1M TRANSACTIONS WITH RELATED ORGANIZATIONS THE ORGANIZATION SHARES FACILITIES AND EQUIPMENT WITH JAEB CENTER RESEARCH TRUST INC NEITHER ORGANIZATION ASSIGNS A VALUE TO THIS TRANSACTION SCHEDULE R PART V LINE 1N TRANSACTIONS WITH RELATED ORGANIZATIONS THE ORGANIZATION SHARES PAID EMPLOYEES WITH JAEB CENTER RESEARCH TRUST INC AN EMPLOYEE OF JAEB CENTER FOR HEALTH RESEARCH INC DOES THE BOOKKEEPING FOR THE TRUST</Explanation>
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    </IRS990ScheduleR>
  </ReturnData>
</Return>