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        <EINOfRecipient>362177139</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>146127</AmountOfCashGrant>
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      <RecipientTable>
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          <BusinessNameLine1>University of Colorado Denver</BusinessNameLine1>
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          <AddressLine1>PO Box 6508</AddressLine1>
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          <State>CO</State>
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        <EINOfRecipient>846000555</EINOfRecipient>
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          <BusinessNameLine1>University of Connecticut Health Center</BusinessNameLine1>
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      <RecipientTable>
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          <BusinessNameLine1>University of Illinois at Chicago</BusinessNameLine1>
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          <AddressLine1>PO Box 20787</AddressLine1>
          <City>Springfield</City>
          <State>IL</State>
          <ZIPCode>62708</ZIPCode>
        </AddressUS>
        <EINOfRecipient>376000511</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>375551</AmountOfCashGrant>
        <PurposeOfGrant>Research support</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>University of Illinois at Urbana-Champaign</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>PO Box 4610</AddressLine1>
          <City>Springfield</City>
          <State>IL</State>
          <ZIPCode>62708</ZIPCode>
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        <EINOfRecipient>376000511</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>129174</AmountOfCashGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
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        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>144195</AmountOfCashGrant>
        <PurposeOfGrant>Research support</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>University of Kentucky</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>109 Kinkead Hall</AddressLine1>
          <City>Lexington</City>
          <State>KY</State>
          <ZIPCode>40506</ZIPCode>
        </AddressUS>
        <EINOfRecipient>616033693</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>151236</AmountOfCashGrant>
        <PurposeOfGrant>Research support</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>University of Louisville</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>Med Center One</AddressLine1>
          <City>Louisville</City>
          <State>KY</State>
          <ZIPCode>40292</ZIPCode>
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        <EINOfRecipient>237078461</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>237508</AmountOfCashGrant>
        <PurposeOfGrant>Research support</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>University of Maryland</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>PO Box 41428</AddressLine1>
          <City>Baltimore</City>
          <State>MD</State>
          <ZIPCode>21203</ZIPCode>
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        <EINOfRecipient>526002033</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>89412</AmountOfCashGrant>
        <PurposeOfGrant>Research support</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>University of Massachusetts Amherst</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>70 Butterfield Terrance</AddressLine1>
          <City>Amherest</City>
          <State>MA</State>
          <ZIPCode>01003</ZIPCode>
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        <EINOfRecipient>542084125</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>110359</AmountOfCashGrant>
        <PurposeOfGrant>Research support</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>University of Michigan Ann Arbor</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>3003 S State st</AddressLine1>
          <City>Ann Arbor</City>
          <State>MI</State>
          <ZIPCode>48109</ZIPCode>
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        <EINOfRecipient>386006309</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>509691</AmountOfCashGrant>
        <PurposeOfGrant>Research support</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>University of North Carolina at Chapel Hill</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>PO Box 402410</AddressLine1>
          <City>Atlanta</City>
          <State>GA</State>
          <ZIPCode>30384</ZIPCode>
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        <EINOfRecipient>566001393</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>874017</AmountOfCashGrant>
        <PurposeOfGrant>Research support</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>University of Pennsylvania Health System</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>3451 Walnut st</AddressLine1>
          <City>Philadelphia</City>
          <State>PA</State>
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        <EINOfRecipient>311538725</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
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        <PurposeOfGrant>Research support</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>University of Rochester Medical Center</BusinessNameLine1>
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      <RecipientTable>
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        <EINOfRecipient>741717115</EINOfRecipient>
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        <AmountOfCashGrant>146596</AmountOfCashGrant>
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          <State>TX</State>
          <ZIPCode>77030</ZIPCode>
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        <EINOfRecipient>741761309</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>384486</AmountOfCashGrant>
        <PurposeOfGrant>Research support</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>University of Texas Southwestern Medical Center</BusinessNameLine1>
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          <AddressLine1>PO Box 841753</AddressLine1>
          <City>Dallas</City>
          <State>TX</State>
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          <City>Chicago</City>
          <State>IL</State>
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          <BusinessNameLine1>Veterans Administration Medical Center Portland</BusinessNameLine1>
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          <State>OR</State>
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          <State>MO</State>
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          <City>Detroit</City>
          <State>MI</State>
          <ZIPCode>48202</ZIPCode>
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        <EINOfRecipient>386028429</EINOfRecipient>
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        <PurposeOfGrant>Research support</PurposeOfGrant>
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      <TotalNbrOf501C3AndGovtGrants>80</TotalNbrOf501C3AndGovtGrants>
      <TotalNbrOfOtherOrganizations>6</TotalNbrOfOtherOrganizations>
      <Form990ScheduleIPartIV>
        <Identifier>Form 990, Schedule I, Part I, Line 2</Identifier>
        <Explanation>The society utilized a volunteer committee of renowned scientists and neurologists to select research grants for funding in the U.S. and abroad all grantees are required to provide scientific and financial progress reports on a quarterly basis which are reviewed by qualified staff. Upon acceptance of the progress reports, payments are disbursed to grantees.</Explanation>
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    </IRS990ScheduleI>
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    <IRS990ScheduleO documentId="IRS990ScheduleO">
      <GeneralExplanation>
        <Identifier>Form 990, Part III, Line 4d</Identifier>
        <ReturnReference>Form 990, Part III, Line 4d</ReturnReference>
        <Explanation>Public education - represents programs conducted for the purpose of informing and alerting the general public about multiple sclerosis and its various manifestations.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Line 11a</Identifier>
        <Explanation>A copy of the Form 990 and accompanying schedules is provided to the entire board with a period for providing comments, edits or corrections prior to the final review by the Audit Committee. The Audit Committee reviews the Form 990 and accompanying schedules along with any feedback provided by members of the board prior to their final approval and submission to the IRS.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Line 12c</Identifier>
        <Explanation>On an annual basis, the audit committee reviews the conflict of interest forms filed by trustees, officers and employees for potential conflicts. Where potential conflicts exist, the trustee, officer, or employee is not allowed to participate in any vote and transactions are subject to competitive bidding. At the current time, no potential conflicts of interest have been identified.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Line 15a</Identifier>
        <Explanation>The compensation committee which is comprised of at least three independent trustees determines the compensation of the president and other key employees. The committee is provided with comparable salary data for presidents and other key positions at other voluntary health agencies of similar budget size(s) and national influence. In addition, the president's performance is evaluated annually by the committee of independent trustees.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Line 15b</Identifier>
        <Explanation>The president or her designee conducts performance evaluations for the other key employees the outcome of which is shared with the compensation committee to help inform their decisions about compensation.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Line 19</Identifier>
        <Explanation>The organization's financial statements are available on its website and charity navigator. Its governing documents and conflict of interest policy are available upon request.</Explanation>
      </GeneralExplanation>
    </IRS990ScheduleO>
    <IRS990ScheduleR documentId="IRS990ScheduleR">
      <Form990ScheduleRPartI>
        <NameOfDisregardedEntity>
          <BusinessNameLine1>Fast Forward llc</BusinessNameLine1>
        </NameOfDisregardedEntity>
        <AddressUS>
          <AddressLine1>733 Third Avenue</AddressLine1>
          <City>New York</City>
          <State>NY</State>
          <ZIPCode>10017</ZIPCode>
        </AddressUS>
        <EIN>261933619</EIN>
        <PrimaryActivities>research</PrimaryActivities>
        <LegalDomicileState>DE</LegalDomicileState>
        <TotalIncome>4878011</TotalIncome>
        <EOYAssets>5399627</EOYAssets>
        <DirectControllingEntityName>
          <BusinessNameLine1>na</BusinessNameLine1>
        </DirectControllingEntityName>
      </Form990ScheduleRPartI>
    </IRS990ScheduleR>
  </ReturnData>
</Return>