2011-08-22T10:02:24-05:00 2010-12-31 HEARD MCELROY & VESTAL LLC 333 TEXAS STREET SHREVEPORT LA 71101 990 2010-01-01 760497352 INSTITUTE OF ORTHOPEDIC RESEARCH AND EDUCATION INST 7136104270 6550 FANNIN STREET SUITE 2512 HOUSTON TX 77030 JIM BOCELL MD 7136104270 2011-08-08 1 ROY E PRESTWOOD 3184291525 2010 2016-02-24 21:20:13Z JIM BOCELL MD 6550 FANNIN STREET SUITE 2512 HOUSTON TX 77030 969430 0 X WWW.IORE.NET X 1995 TX IORE'S FUNDAMENTAL RESEARCH MISSION IS TO PROVIDE THE STAFF AND FACILITIES REQUIRED TO ENABLE ORTHOPEDIC FACULTY, RESIDENTS AND FELLOWS TO ACHIEVE NATIONAL AND INTERNATIONAL PROMINENCE THROUGH APPLIED RESEARCH OF THE VERY HIGHEST STANDARD. 5 5 25 15 0 0 0 150000 1190936 730928 2635 3264 102356 85238 1295927 969430 0 0 0 0 720041 703795 0 0 0 589234 493368 1309275 1197163 -13348 -227733 663573 435086 754 0 662819 435086 X IORE'S FUNDAMENTAL RESEARCH MISSION IS TO PROVIDE THE STAFF AND FACILITIES REQUIRED TO ENABLE ORTHOPEDIC FACULTY, RESIDENTS AND FELLOWS TO ACHIEVE NATIONAL AND INTERNATIONAL PROMINENCE THROUGH APPLIED RESEARCH OF THE VERY HIGHEST STANDARD. 0 0 99753 69400 ATO ZIMMER KNEEWE RECEIVED FUNDING TO TEST THE TIBIO-FEMORAL AND PATELLO-FEMORAL KINEMATICS OF THREE DESIGNS OF TOTAL KNEE REPLACEMENTS IN WHICH THE SHAPE AND ALIGNMENT OF THE FEMORAL SULCUS HAD BEEN CHANGED TO IMPROVE PATELLAR TRACKING. THESE THREE DESIGNS WERE DEVELOPED WITH PARAMETRIC CHANGES TO COMMON GEOMETRIC PARAMETERS BASED ON MORPHOLOGICAL STUDIES. THESE DESIGNS WERE DEVELOPED AS POTENTIAL SOLUTIONS TO KNEE REPLACEMENT WHEN IMPLANTED USING DIFFERENT STANDARD METHODS OF ALIGNING THE KNEE JOINT BEFORE MAKING BONY RESECTIONS FOR INSTALLATION OF THE PROSTHETIC COMPONENTS. SIX KNEES WERE PREPARED IN THE IORE LABORATORY BY TWO EXPERIENCED KNEE SURGEONS AND THEN TESTED IN OUR CADAVERIC ACTIVITY SIMULATOR. A FINAL REPORT WAS PREPARED DESCRIBING THE DIFFERENCES IN IMPLANT DESIGN AND SURGICAL ALIGNMENT. 89858 149668 TMH PROJECTSDURING THE 2010 CALENDAR YEAR IORE SUPPORTED ACADEMIC RESEARCH PROJECTS COMPLETED BY METHODIST FELLOWS IN JOINT REPLACEMENT AND SPORTS MEDICINE. THESE PROJECTS RANGED FROM CADAVERIC STUDIES SIMULATING MUSCULO-SKELETAL FUNCTION TO QUESTIONNAIRE/OUTCOME STUDIES QUANTIFYING THE RESULTS OF SURGICAL PROCEDURES. TYPICAL RESEARCH STUDIES INCLUDED:1. ANATOMIC ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION WITH PATELLAR TENDON RESTORES KNEE STABILITY AND KINEMATICS IN MEDIAL MENISCAL DEFICIENCY WHICH HYPOTHESIZED THAT ANATOMICALLY PLACED PATELLAR TENDON AUTOGRAFT COULD RESTORE KNEE STABILITY IN VARIED CONDITIONS OF MEDIAL MENISCUS DEFICIENCY. EIGHT FRESH-FROZEN CADAVERIC KNEES WERE TESTED IN VARYING STATES OF MENISCAL AND ACL DEFICIENCY. THE RESULTS WERE SUBMITTED FOR PUBLICATION TO A PEER REVIEWED JOURNAL. 2. A SECOND PROJECT WAS "KNEE INSTABILITY DURING STAIR DESCENT AFTER TKA: EXPERIMENTAL SIMULATION" IN WHICH THE ACTIVITY OF WALKING DOWN STAIRS WAS RECREATED USING CADAVERIC KNEE SPECIMENS ANIMATED IN A KNEE ACTIVITY SIMULATOR. AFTER MEASUREMENT OF THE KINEMATIC RESPONSES OF THE NORMAL KNEE, THE RESEARCH FELLOW PERFORMED A TOTAL KNEE REPLACEMENT AND THE TESTING PROCEDURES WERE REPEATED. THE EXPERIMENT WAS PERFORMED USING 3 DIFFERENT DESIGNS OF KNEE PROSTHESIS WITH HYPOTHETICAL DIFFERENCES IN TRANSLATIONAL AND ROTATIONAL STABILITY. THIS WORK IS THE SUBJECT OF AN ABSTRACT SUBMITTED TO THE ORTHOPEDIC RESEARCH SOCIETY FOR PRESENTATION IN 2012. 242240 273131 FRACTURE PUTTY PROJECTS (LONG BONE AND SPINAL FRACTURES)IORE IS PARTICIPATING IN A STUDY FUNDED BY DEFENSE ADVANCED RESEARCH PROJECTS AGENCY (DARPA) WHICH IS DEVELOPING "FRACTURE PUTTIES" OR MATERIALS FOR THE ACUTE STABILIZATION OF BONY FRACTURES. THESE ADVANCED MATERIALS ARE DESIGNED TO INDUCE HEALING OF LONG BONES AND THE SPINAL COLUMN AFTER IMPLANTATION INTO THE BODY ON THE BATTLEFIELD OR AFTER MEDICAL EVACUATION OF MILITARY PERSONNEL. THIS PROJECT ENTAILS THE USE OF NANO-TECHNOLOGY, ARTIFICIAL BIOMATERIALS AND STEM CELLS AND IS BEING MANAGED BY THE UNIVERSITY OF TEXAS WITH THE ACTIVE COLLABORATION OF SEVERAL DIFFERENT INSTITUTIONS WITHIN TEXAS, INCLUDING RICE UNIVERSITY, A&M UNIVERSITY, AND NORTHWESTERN UNIVERSITY IN ILLINOIS. IORE IS PROVIDING EXPERTISE IN THE DESIGN AND MANUFACTURE OF THE IMPLANTABLE DEVICES TO ACCELERATE REPAIR, AND IN THE TESTING AND SIMULATION OF THE FINAL DESIGNS BEFORE AND AFTER IMPLANTATION IN SHEEP. A SIDE PROJECT ALSO ENTAILS STABILIZATION OF ACUTE SPINE FRACTURES USING BIOLOGICALLY ACTIVE PUTTIES. ALL OF THE DEVELOPMENT WORK AND BACKGROUND RESEARCH PERTAINING TO THIS APPLICATION IS BEING CONDUCTED AT IORE, IN COLLABORATION WITH DR BRAD WEINER, A SPINE SURGEON AND MEMBER OF THE IORE BOARD. THE ULTIMATE GOAL OF THIS PROJECT IS TO ACUTELY RESTORE THE STRENGTH AND STABILITY OF THE SPINE AFTER A CATASTROPHIC INJURY AND THEN TO ADMINISTER IMMEDIATE IMPLANTABLE THERAPIES TO DIRECT THE ACUTE REPAIR OF ASSOCIATED INJURIES OF THE SPINAL CORD. 449583 238729 OTHER ORTHOPEDIC RESEARCH PROJECTS. 449583 238729 881434 1 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 15 0 1 25 1 0 0 0 0 0 0 0 0 0 0 X 5 5 0 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 1 0 X X KIM MCCONN 7136104270 6550 FANNIN STREET SUITE 2512 HOUSTON TX 77030 X WILLIAM J BRYAN MD 0.50 X 0 0 0 BRADLEY WEINER MD 1.00 X X 0 0 0 JAMES R BOCELL MD 1.00 X X 0 0 0 KENNETH B MATHIS MD 1.00 X 0 0 0 STEPHEN INCAVO MD 0.50 X 0 0 0 0 0 0 0 0 0 0 0 150000 150000 RESEARCH SERVICES 541700 730928 730928 730928 3264 3264 83504 83504 MISCELLANEOUS INCOME 900099 1734 1734 1734 969430 730928 0 88502 570381 528880 41501 25178 23633 1545 63337 59449 3888 44899 42143 2756 42000 42000 1675 1675 3793 3793 7461 5642 1819 233 233 57383 49923 7460 33761 20451 13310 4564 3674 890 26245 26245 46187 46187 SUPPLIES 122566 100675 21891 LOSS ON DISPOSAL OF ASS 76589 76589 LAB EQUIPMENT EXPENSE 21729 21729 CONTRACT LABOR 18229 9000 9229 POSTAGE & SHIPPING 7609 6075 1534 23344 8485 14859 1197163 881434 315729 0 287639 148488 161299 26558 135840 502434 381164 214635 121270 0 2930 663573 435086 754 754 0 X 0 0 0 0 662819 435086 662819 435086 663573 435086 -227733 0 X 0 0 0 X 675133 343580 615000 150000 1783713 575789 463751 546187 1190936 595087 3371750 1250922 807331 1161187 1190936 745087 5155463 0 612349 320042 236529 556910 196904 1922734 612349 320042 236529 556910 196904 1922734 3232729 21495 23933 9538 104991 86768 246725 21495 23933 9538 104991 86768 246725 1734 1734 1272417 831264 1170725 1295927 833589 5403922 0.59820 0.54610 0.04570 0.01250 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 0 90000 25481 64519 412434 355683 56751 0 121270 FORM 990, PART VI, SECTION B, LINE 11 A COPY OF THE 990 IS PROVIDED TO THE ORGANIZATION'S GOVERNING BODY BEFORE IT IS FILED. FORM 990, PART VI, SECTION B, LINE 12C THE BOARD REGULARLY AND CONSISTENTLY MONITORS AND ENFORCES THE COMPLIANCE WITH THE CONFLICT OF INTEREST POLICY BY OVERSEEING THE OPERATIONS OF THE ORGANIZATION. FORM 990, PART VI, SECTION B, LINE 15 THE PROCESS FOR DETERMINING COMPENSATION INCLUDES A REVIEW AND APPROVAL OF THE BOARD, COMPARABILITY DATA, AND CONTEMPORANEOUS SUBSTANTIATION. FORM 990, PART VI, SECTION C, LINE 19 THE ORGANIZATION MAKES ITS GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY, AND FINANCIAL STATEMENTS AVAILABLE TO THE PUBLIC UPON REQUEST. 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