2012-11-13T12:58:33-06:00 2011-12-31 521392008 GELMAN ROSENBERG & FREEDMAN 4550 MONTGOMERY AVE SUITE 650N BETHESDA MD 208142930 990 2011-01-01 830431851 PATH VACCINE SOLUTIONS PATH 2062853500 2201 WESTLAKE AVENUE NO 200 SEATTLE WA 98121 MARLOW KEE 2062853500 2012-11-13 1 3019519090 2011 2016-02-24 21:20:13Z MARLOW KEE 2201 WESTLAKE AVENUE NO 200 SEATTLE WA 98121 42220153 0 X WWW.PATH.ORG X 2006 WA THE MISSION OF PATH VACCINE SOLUTIONS (PVS) IS TO IMPROVE THE HEALTH OF CHILDREN IN LOW-INCOME COUNTRIES BY ACCELERATING THE DEVELOPMENT OF VACCINES THAT WILL BE EFFECTIVE AND AFFORDABLE IN COUNTRIES THAT NEED THEM MOST. FROM INITIAL DISCOVERY THROUGH CLINICAL TRIALS, PVS WORKS WITH COMMERCIAL PARTNERS, SUCH AS VACCINE MANUFACTURERS AND BIOTECHNOLOGY FIRMS, AND NONPROFIT PARTNERS, SUCH AS UNIVERSITIES AND RESEARCH INSTITUTIONS, TO SHORTEN THE TIMELINE FOR VACCINE DEVELOPMENT. 7 3 0 0 0 0 32724826 17377524 3500 0 53857 805398 7148 -1385 32789331 18181537 30660682 30822158 0 0 0 0 0 0 0 5260313 6404407 35920995 37226565 -3131664 -19045028 151102797 133507981 4781234 6691219 146321563 126816762 X PVS WORKS WITH PARTNERS TO DEVELOP NEW VACCINES BY PROVIDING FUNDING AND EXPERTISE IN NONCLINICAL DEVELOPMENT, MANUFACTURING, AND CLINICAL DEVELOPMENT, WITH A FOCUS ON LOW-INCOME COUNTRIES. IN RETURN, PARTNERS AGREE TO TERMS THAT WILL HELP ENSURE THAT THE PRODUCTS ARE AFFORDABLE AND AVAILABLE IN DEVELOPING COUNTRIES. 0 0 37226565 30822158 PVS WORKS TO PREVENT DEATHS FROM PNEUMONIA, INFLUENZA, RESPIRATORY SYNCYTIAL VIRUS, POLIO, AND DIARRHEA AMONG CHILDREN AROUND THE WORLD. WE ACCELERATE THE DEVELOPMENT OF SAFE, EFFICACIOUS, AND AFFORDABLE VACCINES IN PARTNERSHIP WITH PUBLIC AND PRIVATE GROUPS. IN 2011 PVS ADVANCED RESEARCH AND DEVELOPMENT OF A NUMBER OF PROMISING PNEUMOCOCCAL VACCINE CANDIDATES AND RELATED TECHNOLOGIES. THIS WORK RANGED FROM PRELIMINARY RESEARCH TO PRECLINICAL DEVELOPMENT TO CLINICAL TRIALS FOR SEVERAL CANDIDATES. FOR EXAMPLE, WE MADE PREPARATIONS TO ADVANCE AN INACTIVATED WHOLE-CELL VACCINE INTO PHASE 1 CLINICAL TRIALS, AND WE LAUNCHED A TWO-STAGE PHASE 2 CLINICAL TRIAL IN THE GAMBIA OF A VACCINE AGAINST STREPTOCOCCUS PNEUMONIAE. OUR PARTNERS INCLUDED ACADEMIC GROUPS (SUCH AS THE UNIVERSITY OF ADELAIDE, THE UNIVERSITY OF OKLAHOMA, AND THE LONDON SCHOOL OF HYGIENE & TROPICAL MEDICINE), INDUSTRY PARTNERS (INCLUDING GENOCEA BIOSCIENCES, GLAXOSMITHKLINE BIOLOGICALS, LIQUIDIA TECHNOLOGIES, MUCOSIS BV, AND THE SERUM INSTITUTE OF INDIA LTD.), AND HEALTH CARE INSTITUTIONS (SUCH AS BOSTON CHILDREN'S HOSPITAL AND ST. JUDE CHILDREN'S RESEARCH HOSPITAL). DURING 2011 PVS ALSO ADVANCED THE DEVELOPMENT OF PROMISING NEW INFLUENZA VACCINES, FOCUSING ON NOVEL TECHNOLOGIES THAT CAN BE ACCESSIBLE, AFFORDABLE, AND AVAILABLE TO PEOPLE IN LOW-RESOURCE SETTINGS DURING INFLUENZA OUTBREAKS. HIGHLIGHTS INCLUDED COMPLETING PRECLINICAL DEVELOPMENT OF SEVERAL AVIAN LIVE ATTENUATED INFLUENZA VACCINE CANDIDATES, PREPARING FOR TESTING A SEASONAL INFLUENZA VACCINE AMONG CHILDREN IN BANGLADESH, LAUNCHING A CLINICAL STUDY TO DETERMINE THE IMMUNOLOGIC POTENTIAL OF AVIAN LIVE ATTENUATED INFLUENZA VACCINE TO BOOST THE RESPONSE OF INACTIVATED INFLUENZA VACCINES, AND INITIATING A NEW RESPIRATORY SYNCYTIAL VIRUS VACCINE COMPONENT OF OUR INFLUENZA PORTFOLIO. OUR PARTNERS INCLUDED THE INSTITUTE OF EXPERIMENTAL MEDICINE IN RUSSIA, MEDICAGO INC., LENTIGEN, THE UNIVERSITY OF PITTSBURGH, AND THE INFECTIOUS DISEASE RESEARCH INSTITUTE OF SEATTLE.INFECTION WITH ROTAVIRUS IS A MAJOR CAUSE OF SEVERE DIARRHEA AND DEATH AMONG YOUNG CHILDREN IN LOW-INCOME COUNTRIES. PVS AIMS TO ACCELERATE INTRODUCTION OF SAFE, AFFORDABLE, AND EFFECTIVE ROTAVIRUS VACCINES BY PROVIDING TECHNICAL AND FINANCIAL SUPPORT TO EMERGING-COUNTRY MANUFACTURERS. HIGHLIGHTS DURING 2011 INCLUDED WORKING WITH BHARAT BIOTECH INTERNATIONAL LTD. IN INDIA TO SUPPORT THE LAUNCH OF A PHASE 3 EFFICACY TRIAL OF ITS PROMISING VACCINE CANDIDATE; PARTNERING WITH THE SERUM INSTITUTE OF INDIA LTD. TO PREPARE FOR PHASE 3 CLINICAL TRIALS OF ANOTHER TYPE OF ROTAVIRUS VACCINE; AND PROVIDING A SHARED TECHNOLOGY PLATFORM THAT ALLOWS MANUFACTURERS OF NEW ROTAVIRUS VACCINES TO ACCESS A HOST OF NEEDED TECHNOLOGIES, TRAINING, AND TECHNICAL SUPPORT.PVS ALSO ADVANCES RESEARCH AND DEVELOPMENT OF VACCINES AGAINST THE TWO LEADING BACTERIAL CAUSES OF DIARRHEA, SHIGELLA AND ENTEROTOXIGENIC ESCHERICHIA COLI. MUCH OF THIS WORK IS DONE THROUGH PARTNERSHIPS WITH PUBLIC- AND PRIVATE-SECTOR ORGANIZATIONS. KEY ACTIVITIES IN 2011 INCLUDED SIGNING SEVEN NEW PARTNERSHIP AGREEMENTS FOR RESEARCH, DEVELOPMENT, AND TESTING OF VACCINE CANDIDATES AND RELATED TECHNOLOGY; COMPLETING A PHASE 2B CHALLENGE STUDY OF ONE VACCINE CANDIDATE AND HELPING TO SUPPORT THE LAUNCH OF PHASE 1 TRIALS OF TWO OTHER VACCINE CANDIDATES; AND FUNDING AND HOSTING WORKSHOPS IN VIETNAM ON DIARRHEAL DISEASE AND THE USE OF ORAL VACCINES IN INFANTS. OUR PARTNERS INCLUDED THE INTERNATIONAL VACCINE INITIATIVE, OKLAHOMA STATE UNIVERSITY, THE US NAVAL MEDICAL RESEARCH CENTER, MUCOSIS BV, THE UNIVERSITY OF MARYLAND, BALTIMORE, AND THE WALTER REED ARMY INSTITUTE OF RESEARCH. IN 2011, PVS ADDED NEW PROJECTS TO WORK ON VACCINES AGAINST POLIO AND RESPIRATORY SYNCYTIAL VIRUS. 37226565 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 1 1 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 X 7 3 0 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 0 0 0 WA X X MARLOW KEE CHIEF FINANCIAL OFFICER 2062853500 2201 WESTLAKE AVE SUITE 200 SEATTLE WA 98121 CHRISTOPHER J ELIAS 1.00 X X 0 524445 39496 JACQUELINE D SHERRIS 1.00 X X 0 244324 19102 ERIC G WALKER 1.00 X X 0 235336 35164 DAN LASTER 1.00 X 0 216927 27234 N REGINA RABINOVICH 1.00 X 0 0 0 DOUGLAS HOLTZMAN 1.00 X 0 0 0 TOM BREWER 1.00 X 0 0 0 DAVID ALLI 1.00 X 0 143147 25761 0 1364179 146757 0 0 1 0 0 17377524 17377524 754517 754517 24089497 24038616 50881 50881 50881 OTHER REIMBURSEMENT 900099 -1385 -1385 -1385 18181537 0 0 804013 19277039 19277039 11545119 11545119 79876 79876 2883 2883 112832 112832 653828 653828 888 888 277001 277001 5717 5717 32500 32500 2296 2296 1622613 1622613 124793 124793 164384 164384 SUBCONTRACTS 3113499 3113499 LAB SUPPLIES 111374 111374 TAXES 64312 64312 EQUIPMENT R&M & PROCURE 9991 9991 25620 25620 37226565 37226565 0 0 10065380 6827477 80022019 58943532 78013 267335 165118 60937385 67304519 151102797 133507981 4781234 6691219 4781234 6691219 X 146321563 126816762 146321563 126816762 151102797 133507981 X -19045028 -459773 X 0 1 1 X 0 X X X 0 0 0 PATH 911157127 BOX 7 1 37226565 1 37226565 RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 1 EAST ASIA AND THE PACIFIC 0 0 PROGRAM SERVICES VACCINES AND IMMUNIZATIONS 240382 EAST ASIA AND THE PACIFIC 0 0 GRANTS 3850973 EUROPE 0 4 PROGRAM SERVICES VACCINES AND IMMUNIZATIONS 1335193 EUROPE 0 0 GRANTS 2141935 MIDDLE EAST 0 0 PROGRAM SERVICES VACCINES AND IMMUNIZATIONS 520 NORTH AMERICA 0 0 PROGRAM SERVICES VACCINES AND IMMUNIZATIONS 25128 NORTH AMERICA 0 0 GRANTS 575000 RUSSIA AND THE NEWLY INDEPENDENT STATES 0 0 PROGRAM SERVICES VACCINES AND IMMUNIZATIONS 61880 RUSSIA AND THE NEWLY INDEPENDENT STATES 0 0 GRANTS 961913 SOUTH AMERICA 0 0 PROGRAM SERVICES VACCINES AND IMMUNIZATIONS 15 SOUTH ASIA 0 8 PROGRAM SERVICES VACCINES AND IMMUNIZATIONS 656197 SOUTH ASIA 0 0 GRANTS 1759246 SUB-SAHARAN AFRICA 0 0 PROGRAM SERVICES VACCINES AND IMMUNIZATIONS 103756 SUB-SAHARAN AFRICA 0 0 GRANTS 2256051 0 4 0 8 0 12 8231011 5737178 13968189 EAST ASIA VACCINES AND IMMUNIZATIONS 50143 CHECK / WIRE EAST ASIA VACCINES AND IMMUNIZATIONS 6879 CHECK / WIRE EAST ASIA VACCINES AND IMMUNIZATIONS 600000 CHECK / WIRE EAST ASIA VACCINES AND IMMUNIZATIONS 60000 CHECK / WIRE EAST ASIA VACCINES AND IMMUNIZATIONS 900000 CHECK / WIRE EAST ASIA VACCINES AND IMMUNIZATIONS 610000 CHECK / WIRE EAST ASIA VACCINES AND IMMUNIZATIONS 13266 CHECK / WIRE EAST ASIA VACCINES AND IMMUNIZATIONS 19165 CHECK / WIRE EAST ASIA VACCINES AND IMMUNIZATIONS 6554 CHECK / WIRE EAST ASIA VACCINES AND IMMUNIZATIONS 1584965 CHECK / WIRE EUROPE VACCINES AND IMMUNIZATIONS 56349 CHECK / WIRE EUROPE VACCINES AND IMMUNIZATIONS 186711 CHECK / WIRE EUROPE VACCINES AND IMMUNIZATIONS 34507 CHECK / WIRE EUROPE VACCINES AND IMMUNIZATIONS 30387 CHECK / WIRE EUROPE VACCINES AND IMMUNIZATIONS 1147000 CHECK / WIRE EUROPE VACCINES AND IMMUNIZATIONS 211054 CHECK / WIRE EUROPE VACCINES AND IMMUNIZATIONS 35368 CHECK / WIRE EUROPE VACCINES AND IMMUNIZATIONS 289168 CHECK / WIRE EUROPE VACCINES AND IMMUNIZATIONS 150000 CHECK / WIRE NORTH AMERICA VACCINES AND IMMUNIZATIONS 500000 CHECK / WIRE NORTH AMERICA VACCINES AND IMMUNIZATIONS 75000 CHECK / WIRE RUSSIA VACCINES AND IMMUNIZATIONS 961914 CHECK / WIRE SOUTH ASIA VACCINES AND IMMUNIZATIONS 42966 CHECK / WIRE SOUTH ASIA VACCINES AND IMMUNIZATIONS 83227 CHECK / WIRE SOUTH ASIA VACCINES AND IMMUNIZATIONS 65905 CHECK / WIRE SOUTH ASIA VACCINES AND IMMUNIZATIONS 179496 CHECK / WIRE SOUTH ASIA VACCINES AND IMMUNIZATIONS 580974 CHECK / WIRE SOUTH ASIA VACCINES AND IMMUNIZATIONS 143256 CHECK / WIRE SOUTH ASIA VACCINES AND IMMUNIZATIONS 66339 CHECK / WIRE SOUTH ASIA VACCINES AND IMMUNIZATIONS 94057 CHECK / WIRE SOUTH ASIA VACCINES AND IMMUNIZATIONS 449130 CHECK / WIRE SOUTH ASIA VACCINES AND IMMUNIZATIONS 53896 CHECK / WIRE SUB-SAHARAN AFRICA VACCINES AND IMMUNIZATIONS 125494 CHECK / WIRE SUB-SAHARAN AFRICA VACCINES AND IMMUNIZATIONS 241484 CHECK / WIRE SUB-SAHARAN AFRICA VACCINES AND IMMUNIZATIONS 1889073 CHECK / WIRE 23 12 0 0 0 0 0 0 PROCEDURE FOR MONITORING GRANTS OUTSIDE THE U.S.: SCHEDULE F, PART I, LINE 2: SUBRECIPIENTS ARE REQUIRED TO SUBMIT PROGRESS REPORTS, WHICH ARE REVIEWED BY RESPONSIBLE PROGRAM MANAGERS AND PROGRAM ADMINISTRATORS TO ENSURE THAT PROGRAM GOALS ARE ATTAINED IN ACCORDANCE WITH AGREEMENT REQUIREMENTS. THE RESPONSIBLE PROGRAM MANAGERS AND PROGRAM ADMINISTRATORS CONTACT SUBRECIPIENTS WITH QUESTIONS AND FOLLOW UP ON ANY CONCERNS. IN SOME CASES, SUBAWARD TERMS MAY REQUIRE SPECIFIED DELIVERABLES IN ADDITION TO, OR IN LIEU OF, TECHNICAL REPORTS. IN ADDITION, DISCRETIONARY ON-SITE VISITS ARE CONDUCTED TO EVALUATE BOTH COMPLIANCE WITH THE SCIENTIFIC OBJECTIVES OF THE PROJECT AND THE APPROPRIATENESS OF THE SUBRECIPIENT'S ADMINISTRATIVE SYSTEMS AND PROCESSES. 1 UNIVERSITY OF WASHINGTON 4333 BROOKLYN AVE NE BOX 359472 SEATTLE WA 98195 916001537 501(C)(3) 15823 VACCINES AND IMMUNIZATIONS BROOKHAVEN SCIENCE ASSOCIATES LLC BROOKHAVEN NATIONAL LABORATORY BLDG 490-C P O BOX 5000 UPTON NY 119735000 113403915 N/A 6000 VACCINES AND IMMUNIZATIONS TUFTS UNIVERSITY 136 HARRISON AVENUE BOSTON MA 02111 042103634 501(C)(3) 140000 VACCINES AND IMMUNIZATIONS JOHNS HOPKINS UNIVERSITY BLOOMBERG SCHOOL OF PUBLIC HEALTH 615 N WOLFE STREET BALTIMORE MD 21205 520595110 501(C)(3) 119752 VACCINES AND IMMUNIZATIONS WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR) 503 ROBERT GRANT AVENUE SILVER SPRING MD 109107500 520664528 GOVERNMENT 80000 VACCINES AND IMMUNIZATIONS PS3 CORPORATION 13750 SAN PEDRO AVENUE SUITE 640 SAN ANTONIO TX 78232 202159069 N/A 88726 VACCINES AND IMMUNIZATIONS TULANE EDUCATIONAL FUND 1430 TULANE AVENUE TB-32 NEW ORLEANS LA 701122632 720423889 N/A 8000 VACCINES AND IMMUNIZATIONS NAT INS OF ALLERGY & INFECTIOUS DISEASE (NIAID) 6610 ROCKLEDGE DRIVE SUITE 2800 MSC 6606 BETHESDA MD 208926606 520858115 GOVERNMENT 126000 VACCINES AND IMMUNIZATIONS LIQUIDIA TECHNOLOGIES INC 419 DAVIS DRIVE SUITE 100 DURHAM NC 27713 201926605 N/A 1496938 VACCINES AND IMMUNIZATIONS JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH OFFICE OF RESEARCH ADMINISTRATION 615 N WOLFE STREET W1100 BALTIMORE MD 21205 520595110 501(C)(3) 162829 VACCINES AND IMMUNIZATIONS CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER 3333 BURNET AVENUE CINCINNATI OH 45229 310833936 501(C)(3) 46886 VACCINES AND IMMUNIZATIONS INFECTIOUS DISEASE RESEARCH INSTITUTE 1124 COLUMBIA STREET SUITE 400 SEATTLE WA 98104 911608978 501(C)(3) 44181 VACCINES AND IMMUNIZATIONS GENOCEA BIOSCIENCES INC 161 FIRST STREET CAMBRIDGE MA 02139 510596811 N/A 432126 VACCINES AND IMMUNIZATIONS JOHNS HOPKINS UNIVERSITY BLOOMBERG SCHOOL OF PUBLIC HEALTH 615 N WOLFE STREET BALTIMORE MD 21205 520595110 501(C)(3) 28055 VACCINES AND IMMUNIZATIONS EMORY UNIVERSITY 1599 CLIFTON RD NE 4TH FLOOR MAILSTOP 1499/001/1BH ATLANTA GA 303224250 580566256 501(C)(3) 170670 VACCINES AND IMMUNIZATIONS WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR) 503 ROBERT GRANT AVENUE SILVER SPRING MD 109107500 520664528 GOVERNMENT 458063 VACCINES AND IMMUNIZATIONS JOHNS HOPKINS UNIVERSITY BLOOMBERG SCHOOL OF PUBLIC HEALTH 615 N WOLFE STREET BALTIMORE MD 21205 520595110 501(C)(3) 600000 VACCINES AND IMMUNIZATIONS UNIVERSITY OF ALABAMA 701 20TH STREET SOUTH AB 1170 BIRMINGHAM AL 352940111 636005396 501(C)(3) 83685 VACCINES AND IMMUNIZATIONS TULANE UNIVERSITY TULANE SCHOOL OF PUBLIC HEALTH 1440 CANAL ST SUITE 2200 NEW ORLEANS LA 70112 720423889 501(C)(3) 49660 VACCINES AND IMMUNIZATIONS LENTIGEN CORPORATION 910 CLOPPER ROAD SUITE 200 GAITHERSBURG MD 20878 861131845 N/A 400000 VACCINES AND IMMUNIZATIONS FOOD & DRUG ADMINISTRATION (FDA) 10903 NEW HAMPSHIRE AVENUE SILVER SPRING MD 20993 530196965 GOVERNMENT 50000 VACCINES AND IMMUNIZATIONS PURDUE UNIVERSITY 610 PURDUE MALL WEST LAFAYETTE IN 479072040 356002041 501(C)(3) 10848 VACCINES AND IMMUNIZATIONS LELAND STANFORD JUNIOR UNIVERSITY 340 PANAMA ST STANFORD CA 943056203 941156365 501(C)(3) 26930 VACCINES AND IMMUNIZATIONS WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR) 503 ROBERT GRANT AVENUE SILVER SPRING MD 109107500 520664528 GOVERNMENT 523357 VACCINES AND IMMUNIZATIONS INFECTIOUS DISEASE RESEARCH INSTITUTE 1124 COLUMBIA STREET SUITE 400 SEATTLE WA 98104 911608978 501(C)(3) 450000 VACCINES AND IMMUNIZATIONS WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR) 503 ROBERT GRANT AVENUE SILVER SPRING MD 109107500 520664528 GOVERNMENT 96250 VACCINES AND IMMUNIZATIONS UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER 1000 SL YOUNG OKLAHOMA CITY OK 73104 736017987 501(C)(3) 169322 VACCINES AND IMMUNIZATIONS BLAIR AND COMPANY LLC 602 WEST LYON FARM DRIVE GREENWICH CT 06831 061515285 N/A 10788 VACCINES AND IMMUNIZATIONS UNIVERSITY OF PITTSBURGH OFFICE OF RESEARCH 123 UNIVERSITY PLACE LOWER LOBBY PITTSBURGH PA 15213 250965591 501(C)(3) 475000 VACCINES AND IMMUNIZATIONS JOHNS HOPKINS UNIVERSITY 615 N WOLFE STREET BALTIMORE MD 21205 520595110 501(C)(3) 1109651 VACCINES AND IMMUNIZATIONS WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR) 503 ROBERT GRANT AVENUE SILVER SPRING MD 109107500 520664528 GOVERNMENT 122350 VACCINES AND IMMUNIZATIONS CHILDREN'S HOSPITAL BOSTON 300 LONGWOOD AVENUE BOSTON MA 02115 042774441 501(C)(3) 198310 VACCINES AND IMMUNIZATIONS ST JUDE CHILDREN'S RESEARCH 262 DANNY THOMAS PLACE MEMPHIS TN 38105 620646012 501(C)(3) 156840 VACCINES AND IMMUNIZATIONS PROGRAM FOR APPROPRIATE TECHNOLOGY IN HEALTH 2201 WESTLAKE AVENUE STE 200 SEATTLE WA 98121 911157127 501(C)(3) 11312403 VACCINES AND IMMUNIZATIONS 27 7 PROCEDURE FOR MONITORING GRANTS IN THE U.S.: PART I, LINE 2: SCHEDULE I, PART I, LINE 2: SUBRECIPIENTS ARE REQUIRED TO SUBMIT PROGRESS REPORTS, WHICH ARE REVIEWED BY RESPONSIBLE PROGRAM MANAGERS AND PROGRAM ADMINISTRATORS TO ENSURE THAT PROGRAM GOALS ARE ATTAINED IN ACCORDANCE WITH AGREEMENT REQUIREMENTS. THE RESPONSIBLE PROGRAM MANAGERS AND PROGRAM ADMINISTRATORS CONTACT SUBRECIPIENTS WITH QUESTIONS AND FOLLOW UP ON ANY CONCERNS. IN SOME CASES, SUBAWARD TERMS MAY REQUIRE SPECIFIED DELIVERABLES IN ADDITION TO, OR IN LIEU OF, TECHNICAL REPORTS. IN ADDITION, DISCRETIONARY ON-SITE VISITS ARE CONDUCTED TO EVALUATE BOTH COMPLIANCE WITH THE SCIENTIFIC OBJECTIVES OF THE PROJECT AND THE APPROPRIATENESS OF THE SUBRECIPIENT'S ADMINISTRATIVE SYSTEMS AND PROCESSES. 0 0 0 0 0 0 0 0 0 CHRISTOPHER J ELIAS 0 410171 0 114074 0 200 0 28828 0 10668 0 563941 0 0 JACQUELINE D SHERRIS 0 244024 0 0 0 300 0 17711 0 1391 0 263426 0 0 ERIC G WALKER 0 234966 0 0 0 370 0 24546 0 10618 0 270500 0 0 DAN LASTER 0 216927 0 0 0 0 0 16666 0 10568 0 244161 0 0 DAVID ALLI 0 143147 0 0 0 0 0 17177 0 8584 0 168908 0 0 PART I, LINE 3 PVS RELIES ON A RELATED ORGANIZATION, PATH, TO DETERMINE COMPENSATION. PATH USES THE FOLLOWING METHODS TO ESTABLISH COMPENSATION: - COMPENSATION COMMITTEE - INDEPENDENT COMPENSATION CONSULTANT - WRITTEN EMPLOYMENT CONTRACT - COMPENSATION SURVEY OR STUDY - APPROVAL BY THE BOARD OR COMPENSATION COMMITTEE FORM 990, PART VI, SECTION B, LINE 11 THE FORM 990 WAS PREPARED BY THE OUTSIDE ACCOUNTING FIRM USING INFORMATION PROVIDED BY PATH ACCOUNTING SERVICES STAFF. PATH SENIOR MANAGEMENT REVIEWED THE DRAFT FORM. A COPY OF THE FINAL 990 WAS SENT TO THE BOARD OF DIRECTORS FOR COMMENT. AFTER THE COMMENT PERIOD, THE PRESIDENT AND CEO SIGNED THE RETURN. FORM 990, PART VI, SECTION B, LINE 12C BOARD MEMBERS, PVS MANAGEMENT, AND ALL STAFF ABOVE A DESIGNATED LEVEL MUST COMPLETE A CONFLICT OF INTEREST DISCLOSURE FORM EACH YEAR. ALL FORMS ARE REVIEWED AND KEPT ON FILE. A CONFLICT MANAGEMENT PLAN IS DEVELOPED FOR ANY EMPLOYEE WITH A SIGNIFICANT ACTUAL OR PERCEIVED CONFLICT OF INTEREST. EACH YEAR AT THE ANNUAL MEETING, THE GENERAL COUNSEL INFORMS BOARD MEMBERS OF THE REQUIREMENT TO DISCLOSE ANY CONFLICT OF INTEREST. EACH BOARD MEMBER COMPLETES AND SIGNS A CONFLICT FORM ANNUALLY. FORM 990, PART VI, SECTION C, LINE 19 PVS'S FINANCIAL STATEMENTS, GOVERNING DOCUMENTS, AND CONFLICT OF INTEREST POLICY ARE MADE AVAILABLE UPON REQUEST. CHANGES IN NET ASSETS OR FUND BALANCES: FORM 990, PART XI, LINE 5: NET UNREALIZED LOSSES ON INVESTMENTS: -459,773. FORM 990, PART VII, SECTION A, COLUMN (B): CHRISTOPHER J. ELIAS, CHAIR, DEVOTED 40 HOURS PER WEEK TO THE PROGRAM FOR APPROPRIATE TECHNOLOGY IN HEALTH (PATH), AS ITS PRESIDENT AND CEO. JACQUELINE D. SHERRIS, VICE CHAIR, DEVOTED 40 HOURS PER WEEK TO PATH AS ITS VICE PRESIDENT OF GLOBAL PROGRAMS. ERIC G. WALKER, TREASURER, DEVOTED 40 HOURS PER WEEK TO PATH AS ITS VICE PRESIDENT OF CORPORATE SERVICES. DAN LASTER, DIRECTOR, DEVOTED 40 HOURS PER WEEK TO PATH AS ITS GENERAL COUNSEL. DAVID ALLI, BOARD SECRETARY, DEVOTED 40 HOURS PER WEEK TO PATH AS ITS DIRECTOR OF ADMINISTRATION AND FINANCE FOR VACCINE DEVELOPMENT. PROGRAM FOR APPROPRIATE TECHNOLOGY IN HEALTH 2201 WESTLAKE AVE SUITE 200 SEATTLE WA 98109 911157127 GLOBAL HEALTH WA 501(C)(3) BOX 7 N/A 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0