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      <TotalSupport>2500319</TotalSupport>
      <PublicSupportPertcentage170>0.85600</PublicSupportPertcentage170>
      <PublicSupportPertcentPriorYear>0.93310</PublicSupportPertcentPriorYear>
      <ThirtyThreePercntTestsCY170>X</ThirtyThreePercntTestsCY170>
      <GeneralExplanation>SCHEDULE A, PART IV, LIST OF UNUSUAL GRANTS: ACCRUED ROYALTY FEES DATE: 04/21/11 AMOUNT: 1400000. CHANGE IN DISCOUNTED PLEDGE DATE: 12/31/09 AMOUNT: 56017.</GeneralExplanation>
    </IRS990ScheduleA>
    <IRS990ScheduleB documentId="RetDoc1234500001">
      <ContributorInfo>
        <ContributorNumber>RESTRICTED</ContributorNumber>
        <ContributorNameBusiness>
          <BusinessNameLine1>RESTRICTED</BusinessNameLine1>
        </ContributorNameBusiness>
        <ContributorAddressUS>
          <AddressLine1>RESTRICTED</AddressLine1>
          <AddressLine2>RESTRICTED</AddressLine2>
          <City>RESTRICTED</City>
          <State>RESTRICTED</State>
          <ZIPCode>RESTRICTED</ZIPCode>
        </ContributorAddressUS>
        <AggregateContributions>RESTRICTED</AggregateContributions>
      </ContributorInfo>
    </IRS990ScheduleB>
    <IRS990ScheduleD documentId="RetDoc1040000001">
      <Equipment>
        <OtherCostOrOtherBasis>12400</OtherCostOrOtherBasis>
        <Depreciation>3268</Depreciation>
        <BookValue>9132</BookValue>
      </Equipment>
      <TotalOfBookValueLandBuildings>9132</TotalOfBookValueLandBuildings>
      <OtherAssets>
        <Description>DEFERRED RESEARCH AND DEVELOPMENT</Description>
        <BookValue>881229</BookValue>
      </OtherAssets>
      <TotalBookValueOtherAssets>881229</TotalBookValueOtherAssets>
      <TotalRevenue>1865458</TotalRevenue>
      <TotalExpenses>856697</TotalExpenses>
      <ExcessOrDeficitForYear>1008761</ExcessOrDeficitForYear>
      <OtherAmount>-50000</OtherAmount>
      <TotalAdjustments>-50000</TotalAdjustments>
      <ExcessOrDeficitPerFS>958761</ExcessOrDeficitPerFS>
      <TotRevenueEtcAuditedFinclStmt>1977794</TotRevenueEtcAuditedFinclStmt>
      <DonatedSrvcAndUseOfFacilities>162336</DonatedSrvcAndUseOfFacilities>
      <RevenueNotRptdF990>162336</RevenueNotRptdF990>
      <RevenueSubtotal>1815458</RevenueSubtotal>
      <OtherRevenuesNotIncluded>50000</OtherRevenuesNotIncluded>
      <RevenueNotRptdOnFinStmt>50000</RevenueNotRptdOnFinStmt>
      <TotalRevenuePerForm990>1865458</TotalRevenuePerForm990>
      <TotExpensesEtcAuditedFinclStmt>1019033</TotExpensesEtcAuditedFinclStmt>
      <DonatedServicesUseOfFacilities>162336</DonatedServicesUseOfFacilities>
      <ExpensesNotRptdF990>162336</ExpensesNotRptdF990>
      <ExpensesSubtotal>856697</ExpensesSubtotal>
      <ExpensesNotRptdOnFinStmt>0</ExpensesNotRptdOnFinStmt>
      <TotalExpensesPerForm990>856697</TotalExpensesPerForm990>
      <Form990ScheduleDPartXIV>
        <Identifier>DESCRIPTION OF UNCERTAIN TAX POSITIONS UNDER FIN 48:</Identifier>
        <ReturnReference>PART X:</ReturnReference>
        <Explanation>THE FOUNDATION HAS RECEIVED A DETERMINATION LETTER FROM THE INTERNAL REVENUE SERVICE INDICATING THAT IT IS EXEMPT FROM INCOME TAXES UNDER SECTION 501(C)(3) OF INTERNAL REVENUE CODE AND IS CLASSIFIED AS AN ORGANIZATION THAT IS NOT A PRIVATE FOUNDATION. ACCORDINGLY, NO PROVISION FOR INCOME TAXES IS INCLUDED IN THE FINANCIAL STATEMENTS. THE FOUNDATION RECOGNIZES UNCERTAIN INCOME TAX POSITIONS USING THE MORE-LIKELY-THAN-NOT APPROACH AS DEFINED IN THE ACCOUNTING STANDARDS CODIFICATION. NO LIABILITY FOR UNCERTAIN TAX POSITIONS HAS BEEN RECORDED IN THE ACCOMPANYING FINANCIAL STATEMENTS. THE FOUNDATIONS 2008 - 2011 TAX YEARS REMAIN OPEN AND SUBJECT TO EXAMINATION.</Explanation>
      </Form990ScheduleDPartXIV>
      <Form990ScheduleDPartXIV>
        <Identifier>PART XI, LINE 8 - OTHER ADJUSTMENTS:</Identifier>
        <Explanation>RETURNED GRANT -50,000.</Explanation>
      </Form990ScheduleDPartXIV>
      <Form990ScheduleDPartXIV>
        <Identifier>PART XII, LINE 4B - OTHER ADJUSTMENTS:</Identifier>
        <Explanation>RETURNED GRANT 50,000.</Explanation>
      </Form990ScheduleDPartXIV>
    </IRS990ScheduleD>
    <IRS990ScheduleI documentId="RetDoc1041900001">
      <RecordsMaintained>1</RecordsMaintained>
      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>CONTROLLERS OFFICE UNIVERSITY OF</AddressLine1>
          <AddressLine2>LOUISVILLE</AddressLine2>
          <City>LOUISVILLE</City>
          <State>KY</State>
          <ZIPCode>40292</ZIPCode>
        </AddressUS>
        <EINOfRecipient>611029626</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>406248</AmountOfCashGrant>
        <AmountOfNonCashAssistance>5297</AmountOfNonCashAssistance>
        <MethodOfValuation>COST</MethodOfValuation>
        <DescriptionOfNonCashAssistance>CRITICAL REAGENTS</DescriptionOfNonCashAssistance>
        <PurposeOfGrant>RESEARCH AND ADVANCEMENT OF CLINICAL TRIALS ASSOCIATED WITH ADULT STEM CELL THERAPIES.</PurposeOfGrant>
      </RecipientTable>
      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>NORTHWESTERN UNIVERSITY</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>633 CLARK STREET</AddressLine1>
          <City>EVANSTON</City>
          <State>IL</State>
          <ZIPCode>60208</ZIPCode>
        </AddressUS>
        <EINOfRecipient>362167817</EINOfRecipient>
        <IRCSection>501(C)(3)</IRCSection>
        <AmountOfCashGrant>37002</AmountOfCashGrant>
        <PurposeOfGrant>RESEARCH AND ADVANCEMENT OF CLINICAL TRIALS ASSOCIATED WITH ADULT STEM CELL THERAPIES.</PurposeOfGrant>
      </RecipientTable>
      <TotalNbrOf501C3AndGovtGrants>2</TotalNbrOf501C3AndGovtGrants>
      <Form990ScheduleIPartIV>
        <Identifier>PROCEDURE FOR MONITORING GRANTS IN THE U.S.:</Identifier>
        <ReturnReference>PART I, LINE 2:</ReturnReference>
        <Explanation>SCHEDULE I, PART I, LINE 2: THE ORGANIZATION MEETS REGULARLY WITH REPRESENTATIVES FROM THE GRANT RECIPIENT(S) AND RECEIVES UPDATES AND REPORTS REGARDING EXPENDITURE OF THE FUNDS.</Explanation>
      </Form990ScheduleIPartIV>
    </IRS990ScheduleI>
    <IRS990ScheduleO documentId="RetDoc1044400001">
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION A, LINE 2</ReturnReference>
        <Explanation>PAULA GRISANTI, CHAIRMAN OF THE BOARD, AND MICHAEL GRISANTI, DIRECTOR, HAVE A FAMILY RELATIONSHIP.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION A, LINE 3</ReturnReference>
        <Explanation>THE ORGANIZATION HAS CONTRACTED ITS FINANCIAL MANAGEMENT OVERSIGHT TO AN OUTSIDE CHIEF FINANCIAL OFFICER AND ITS DAY TO DAY FINANCIAL DUTIES TO A CONTROLLER.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION B, LINE 11</ReturnReference>
        <Explanation>FORM 990 WAS PREPARED BY OUTSIDE ACCOUNTING FIRM AND REVIEWED IN DETAIL BY CONTRACT CFO, CONTRACT CONTROLLER AND BOARD CHAIR. A COPY WAS THEN SENT TO EACH BOARD MEMBER FOR THEIR REVIEW BEFORE THE FORM 990 WAS FILED.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION B, LINE 12C</ReturnReference>
        <Explanation>EVERY PROPOSED TRANSACTION IS REVIEWED TO DETERMINE WHETHER A POSSIBLE CONFLICT COULD EXIST. TO DATE NO POTENTIAL CONFLICTS HAVE BEEN IDENTIFIED.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION B, LINE 15</ReturnReference>
        <Explanation>POLICY HAS BEEN ADOPTED; HOWEVER CURRENTLY THE CHAIR AND OTHER OFFICERS SERVE WITHOUT COMPENSATION. CONTRACTED CFO AND CONTRACTED CONTROLLER ARE PAID ON AN HOURLY BASIS.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION C, LINE 19</ReturnReference>
        <Explanation>THE ORGANIZATION MAKES ITS GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY AND FINANCIAL STATEMENTS AVAILABLE TO THE PUBLIC UPON REQUEST.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>CHANGES IN NET ASSETS OR FUND BALANCES:</Identifier>
        <ReturnReference>FORM 990, PART XI, LINE 5:</ReturnReference>
        <Explanation>RETURNED GRANT -50,000. TOTAL TO FORM 990, PART XI, LINE 5: -50,000.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART XII, LINE 2C:</ReturnReference>
        <Explanation>THE PROCESS HAS NOT CHANGED FROM PRIOR YEAR. THE ORGANIZATIONS BOARD OF DIRECTORS CONTINUE TO SELECT THE INDEPENDENT ACCOUNTANT. THE COMMITTEE CONTINUES TO MEET WITH THE INDEPENDENT AUDITOR AT THE CONCLUSION OF THE ANNUAL AUDIT.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>DESCRIPTION OF RETURNED GRANT</Identifier>
        <ReturnReference>FORM 990, PART XI, LINE 5 AND SCHEDULE D, PART XI, LINE 8</ReturnReference>
        <Explanation>IN 2009 AND 2010, THE FOUNDATION WAS AWARDED GRANTS TO PROVIDE A SPECIFIC TREATMENT TO A DEFINED PATIENT CLASS. AS PART OF THE GRANT AGREEMENT, THE FUNDS WERE TO BE USED PRIOR TO AUGUST 31, 2010 AND 2011, RESPECTIVELY. CERTAIN PROTOCOLS, OUT OF THE CONTROL OF THE FOUNDATION, WERE NOT APPROVED WITHIN THE TIME FRAME ALLOWED IN THE GRANT AGREEMENTS, THUS THE FUNDS WERE UNABLE TO BE USED AND THE GRANTS EXPIRED. THE DONOR HAS INDICATED THAT THE FOUNDATION COULD BE ELIGIBLE FOR FUTURE FUNDING ONCE THE PROTOCOL ISSUES THAT PREVENTED THE FUNDS BEING USED ARE RESOLVED.</Explanation>
      </GeneralExplanation>
    </IRS990ScheduleO>
  </ReturnData>
</Return>