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        <NamePerson>AARON E MILLER MD</NamePerson>
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        <NamePerson>WILLIAM MONAHAN</NamePerson>
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        <NamePerson>KIMBERLY PHILLIPS</NamePerson>
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        <NamePerson>DAN RATTNER</NamePerson>
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        <NamePerson>BRAD W ROBBINS</NamePerson>
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        <NamePerson>Robert Sowinski</NamePerson>
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      <OtherRevenueMisc>
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        <Explanation>MS activism drives change in public policies to bring positive impact for people affected by MS. Together on the frontline, the National MS Society and MS activists nationwide share the stories of those living with MS, connect with decision makers, work with like-minded partners and create systems change to impact the greatest number of people possible. To make this work possible, the National MS Society's home office and chapters work in partnership. In Washington, DC, the Society's Advocacy Department, also referred to as the public policy office, guides our federal policy priorities. State and local activism priorities are determined by both an organizational process and by advocacy staff and government relations volunteers with our 50-state chapter network. Federal Advocacy. The advocacy department is a component of our home office and carries the primary responsibility for federal advocacy, with guidance from the society's federal activism council and input from other interested society members and partners. This office conducts legislative and regulatory issue research on pending issues, sets priorities, develops positions and advocacy strategies for key priority issues, monitors the progress of important bills and proposed regulations, communicates this information to the chapters and MS activists, and manages the advocacy action required to support or oppose various matters. Each spring, the department hosts the national MS society public policy conference in Washington, DC. For the participating chapter volunteers and staff, the conference provides background information on important federal issues, as well as training in advocacy techniques. One of the annual highlights is when conference participants visit their elected federal legislators to gain support for the society's priority issues. The conference is an excellent opportunity for volunteers and chapter staff to engage as ms activists. The Washington, dc office also follows activity in the executive branch agencies that have jurisdiction over important health policy issues. In the federal executive branch, we closely watch any recommendations from the white house on our issues. In addition, we monitor activity in the following departments and programs: department of health and human services (national institutes of Health, Medicare and Medicaid), the social security administration, the food and drug administration (critical path initiatives), and the justice department (equal employment opportunity commission and other offices enforcing the Americans with disabilities act).</Explanation>
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        <Explanation>The endowment fund represents those funds that are designated for the long-term benefit of the Society and are not to be used for operating or capital purposes. However, endowment fund earnings may be used for operating and capital purposes.</Explanation>
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        <PurposeOfGrant>Research Grant</PurposeOfGrant>
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      <RecipientTable>
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          <BusinessNameLine1>Wayne State University</BusinessNameLine1>
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          <AddressLine1>5057 Woodward Avenue Suite 13202</AddressLine1>
          <City>Detroit</City>
          <State>MI</State>
          <ZIPCode>48202</ZIPCode>
        </AddressUS>
        <EINOfRecipient>386028429</EINOfRecipient>
        <IRCSection>501(c)(3)</IRCSection>
        <AmountOfCashGrant>356404</AmountOfCashGrant>
        <PurposeOfGrant>Research Grant</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>Yale University School of Medicine</BusinessNameLine1>
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          <AddressLine1>333 Cedar St</AddressLine1>
          <City>New Haven</City>
          <State>CT</State>
          <ZIPCode>06510</ZIPCode>
        </AddressUS>
        <EINOfRecipient>060646973</EINOfRecipient>
        <IRCSection>501(c)(3)</IRCSection>
        <AmountOfCashGrant>626282</AmountOfCashGrant>
        <PurposeOfGrant>Research Grant</PurposeOfGrant>
      </RecipientTable>
      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>Concert Pharmaceuticals Inc</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>99 Hayden Avenue Suite 500</AddressLine1>
          <City>Lexington</City>
          <State>MA</State>
          <ZIPCode>02421</ZIPCode>
        </AddressUS>
        <EINOfRecipient>204839882</EINOfRecipient>
        <AmountOfCashGrant>705000</AmountOfCashGrant>
        <PurposeOfGrant>Fast Forward-Domestic</PurposeOfGrant>
      </RecipientTable>
      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>Athersys Inc</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>3201 Carnegie Avenue</AddressLine1>
          <City>Cleveland</City>
          <State>OH</State>
          <ZIPCode>44115</ZIPCode>
        </AddressUS>
        <EINOfRecipient>204864095</EINOfRecipient>
        <AmountOfCashGrant>305000</AmountOfCashGrant>
        <PurposeOfGrant>Fast Forward-Domestic</PurposeOfGrant>
      </RecipientTable>
      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>Lineagen Inc</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>423 Wakara Way Suite 200</AddressLine1>
          <City>Salt Lake City</City>
          <State>UT</State>
          <ZIPCode>84108</ZIPCode>
        </AddressUS>
        <EINOfRecipient>204508128</EINOfRecipient>
        <AmountOfCashGrant>280000</AmountOfCashGrant>
        <PurposeOfGrant>Fast Forward-Domestic</PurposeOfGrant>
      </RecipientTable>
      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>DioGenix Inc</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>50 West Watkins Mill Road</AddressLine1>
          <City>Gaithersburg</City>
          <State>MD</State>
          <ZIPCode>20879</ZIPCode>
        </AddressUS>
        <EINOfRecipient>261414582</EINOfRecipient>
        <AmountOfCashGrant>250000</AmountOfCashGrant>
        <PurposeOfGrant>Fast Forward-Domestic</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>The J David Gladstone Institutes</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>Grants and Contracts Officer</AddressLine1>
          <City>San Francisco</City>
          <State>CA</State>
          <ZIPCode>94158</ZIPCode>
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        <EINOfRecipient>237203666</EINOfRecipient>
        <IRCSection>501(c)(3)</IRCSection>
        <AmountOfCashGrant>128690</AmountOfCashGrant>
        <PurposeOfGrant>Fast Forward-Domestic</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>University of California</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>9500 Gilman Dr</AddressLine1>
          <City>La Jolla</City>
          <State>CA</State>
          <ZIPCode>92093</ZIPCode>
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        <EINOfRecipient>946006143</EINOfRecipient>
        <IRCSection>501(c)(3)</IRCSection>
        <AmountOfCashGrant>67285</AmountOfCashGrant>
        <PurposeOfGrant>Fast Forward-Domestic</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>University of Miami</BusinessNameLine1>
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        <AddressUS>
          <AddressLine1>1320 S Dixie Hwy</AddressLine1>
          <City>Coral Gables</City>
          <State>FL</State>
          <ZIPCode>33146</ZIPCode>
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        <EINOfRecipient>590624458</EINOfRecipient>
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      <RecipientTable>
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          <BusinessNameLine1>Acadia</BusinessNameLine1>
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          <AddressLine1>3911 Sorrento Valley Blvd</AddressLine1>
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          <State>CA</State>
          <ZIPCode>92121</ZIPCode>
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        <AmountOfCashGrant>54538</AmountOfCashGrant>
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      <RecipientTable>
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          <City>Pine Brook</City>
          <State>NJ</State>
          <ZIPCode>07058</ZIPCode>
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        <EINOfRecipient>264390281</EINOfRecipient>
        <AmountOfCashGrant>150000</AmountOfCashGrant>
        <PurposeOfGrant>Fast Forward-Domestic</PurposeOfGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>Oregon Health &amp; Science University</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>2525 SW First Avenue Suite 220</AddressLine1>
          <City>Portland</City>
          <State>OR</State>
          <ZIPCode>97201</ZIPCode>
        </AddressUS>
        <EINOfRecipient>931176109</EINOfRecipient>
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        <AmountOfCashGrant>27980</AmountOfCashGrant>
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      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>The Medical Foundation of No Carolina</BusinessNameLine1>
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          <AddressLine1>880 Martin Luther King Jr Blvd</AddressLine1>
          <City>Chapel Hill</City>
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      <RecipientTable>
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          <BusinessNameLine1>Neuroscience Institute NW</BusinessNameLine1>
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          <AddressLine1>IN Methodist Hospital 200 E 89th</AddressLine1>
          <City>Merrilville</City>
          <State>IN</State>
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          <BusinessNameLine1>Mt Sinai School of Medicine</BusinessNameLine1>
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          <AddressLine1>One Gustave L Levy Place</AddressLine1>
          <City>New York</City>
          <State>NY</State>
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        <PurposeOfGrant>Clinical Grant</PurposeOfGrant>
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          <BusinessNameLine1>West County Multiple Sclerosis Center</BusinessNameLine1>
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          <AddressLine1>1176 Town Country Commons</AddressLine1>
          <City>Chesterfield</City>
          <State>MO</State>
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          <BusinessNameLine1>Johns Hopkins University</BusinessNameLine1>
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          <City>Baltimore</City>
          <State>MD</State>
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        <TypeOfGrant>Scholarships</TypeOfGrant>
        <NumberOfRecipients>664</NumberOfRecipients>
        <AmountOfCashGrant>1163425</AmountOfCashGrant>
        <MethodOfValuation>FMV</MethodOfValuation>
        <DescriptionOfNonCashAssistance>N/A</DescriptionOfNonCashAssistance>
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      <Form990ScheduleIPartIII>
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        <NumberOfRecipients>101</NumberOfRecipients>
        <AmountOfCashGrant>105112</AmountOfCashGrant>
        <MethodOfValuation>FMV</MethodOfValuation>
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      <Form990ScheduleIPartIII>
        <TypeOfGrant>Clinical Grant</TypeOfGrant>
        <NumberOfRecipients>1</NumberOfRecipients>
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      <Form990ScheduleIPartIV>
        <Identifier>Form 990, Schedule I, Part I, Line 2</Identifier>
        <Explanation>The society utilized a volunteer committee of renowned scientists and neurolYgists to select research grants for funding in the U.S. and abroad all grantees are required to provide scientific and financial progress reports on a quarterly basis which are reviewed by qualified staff. Upon acceptance of the progress reports, payments are disbursed to grantees.</Explanation>
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    </IRS990ScheduleJ>
    <IRS990ScheduleO documentId="IRS990ScheduleO">
      <GeneralExplanation>
        <Identifier>Form 990, Part III, Line 4d</Identifier>
        <Explanation>Public Education represents programs conducted for the purpose of informing and alerting the general public about multiple sclerosis and its effects, the distribution of literature and other materials designed to increase the public's awareness and knowledge about this disease, including complexity and variety of symptoms or physical conditions, plus all other costs or expenses which directly relate to the performance of health educational service. Professional Education and Training represents activities or programs designed to improve the knowledge, skills and critical judgment of physicians and other healthcare professionals engaged (directly or indirectly) in providing client services by keeping them abreast of new diagnostic techniques, therapies, etc.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Line 7b</Identifier>
        <Explanation>The delegate assembly elects Governing Body, approves any by-law changes and approves the strategic response.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Line 11b</Identifier>
        <Explanation>THE IRS FORM 990 AND ACCOMPANYING SCHEDULES are PROVIDED TO THE AUDIT COMMITTEE MEMBERS FOR REVIEW, COMMENTS,CORRECTIONS AND EDITS. THE REVIEW COMMENTS OF THE AUDIT COMMITTEE ARE INCORPORATED INTO THE IRS FORM 990 BY THE VICE PRESIDENT FINANCE. A MEETING OF THE AUDIT COMMITTEE IS HELD TO APPROVE THE IRS FORM 990, AND TO APPROVE DISTRIBUTION TO THE ENTIRE NATIONAL MULTIPLE SCLEROSIS SOCIETY BOARD OF DIRECTORS. THE BOARD OF DIRECTORS ARE GIVEN A PERIOD OF TIME TO REVIEW BEFORE AND COMMENT THE IRS FORM 990 IS FILED WITH THE INTERNAL REVENUE SERVICE.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Line 12c</Identifier>
        <Explanation>ALL STAFF AND MEMBERS OF THE NATIONAL MULTIPLE SCLEROSIS SOCIETY BOARD OF DIRECTORS ARE REQUIRED TO COMPLETE A CONFLICT OF INTEREST SURVEY. THE SURVEYS ARE REVIEWED BY THE CHIEF LEGAL OFFICER FOR POTENTIAL CONFLICTS. ON A QUARTERLY BASIS, THE CHIEF LEGAL OFFICER PRESENTS ALL EXISTING CONFLICTS TO THE AUDIT COMMITTEE FOR REVIEW. WHERE CONFLICTS EXIST, THE BOARD MEMBER, TRUSTEE, OFFICER, OR EMPLOYEE ARE NOT ALLOWED TO PARTICIPATE IN ANY VOTE AND TRANSACTIONS ARE SUBJECT TO BIDDING. AS OF SEPTERMBER 30, 2012, NO CONFLICTS HAVE BEEN IDENTIFIED.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Line 15a and 15b</Identifier>
        <Explanation>THE COMPENSATION COMMITTEE WHICH IS COMPRISED OF AT LEAST THREE (3) INDEPENDENT BOARD MEMBERS DETERMINES THE COMPENSATION OF THE PRESIDENT &amp; CEO AND ALL OTHER KEY EMPLOYEES. THE COMMITTEE IS PROVIDED WITH COMPARABLE SALARY INFORMATION DATA FOR ALL POSTIONS AT OTHER VOLUNTARY HEALTH CARE AGENCIES OF SIMILAR BUDGET SIZE(S) AND NATIONAL INFLUENCE. THE PRESIDENT &amp; CEO'S PERFORMANCE IS EVALUATED ON AN ANNUAL BASIS BY THE MEMBERS OF THE COMPENSATION COMMITTEE. THE PRESIDENT &amp; CEO, OR HER DESIGNEE CONDUCT PERFORMANCE EVALUATIONS FOR THE OTHER KEY EMPLOYEES. THE OUTCOME OF THESE EVALUATIONS IS SHARED WITH THE COMPENSATION COMMITTEE TO HELP INFORM THEIR DECISIONS ABOUT COMPENSATION.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part VI, Line 19</Identifier>
        <Explanation>THE NATIONAL MULTIPLE SCLEROSIS IRS FORM 990,IRS FORM 990-T, AND AUDITED FINANCIAL STATEMENTS ARE AVAILABLE AT WWW.NMSS.ORG, AND ON THE CHARITY NAVIGATOR WEBSITE. THE GOVERNING DOCUMENTS AND CONFLICT OF INTEREST POLICY AVAILABLE UPON REQUEST.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990 Part X, line 12</Identifier>
        <Explanation>Fast Forward Warrants $801,073-FMV</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part X, Line 15</Identifier>
        <Explanation>Israeli bonds $6,000 Charitable Gift Annuity $116,832 Total other assets: $122,832</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Form 990, Part XI, Line 5</Identifier>
        <Explanation>The other change in net assets is as follows as of September 30, 2012: Unrealized gains on investments $2,313,154</Explanation>
      </GeneralExplanation>
    </IRS990ScheduleO>
    <IRS990ScheduleR documentId="IRS990ScheduleR">
      <Form990ScheduleRPartI>
        <NameOfDisregardedEntity>
          <BusinessNameLine1>Fast Forward llc</BusinessNameLine1>
        </NameOfDisregardedEntity>
        <AddressUS>
          <AddressLine1>733 Third Avenue</AddressLine1>
          <City>New York</City>
          <State>NY</State>
          <ZIPCode>10017</ZIPCode>
        </AddressUS>
        <EIN>261933619</EIN>
        <PrimaryActivities>research</PrimaryActivities>
        <LegalDomicileState>DE</LegalDomicileState>
        <TotalIncome>693961</TotalIncome>
        <EOYAssets>38067</EOYAssets>
        <DirectControllingEntityName>
          <BusinessNameLine1>na</BusinessNameLine1>
        </DirectControllingEntityName>
      </Form990ScheduleRPartI>
    </IRS990ScheduleR>
  </ReturnData>
</Return>