2013-11-08T15:50:56-06:00 2012-12-31 720398470 HEARD MCELROY & VESTAL LLC 333 TEXAS STREET SUITE 1525 SHREVEPORT LA 71101 990 2012-01-01 760497352 INSTITUTE OF ORTHOPEDIC RESEARCH AND EDUCATION INST 7136104270 6550 FANNIN STREET SUITE 2512 HOUSTON TX 77030 JIM BOCELL MD 7136104270 2013-11-07 1 ROY E PRESTWOOD P00419967 3184291525 2012 2016-02-25 16:41:14Z JIM BOCELL MD 6550 FANNIN STREET SUITE 2512 HOUSTON TX 77030 1274848 0 X WWW.IORE.NET X 1995 TX IORE'S FUNDAMENTAL RESEARCH MISSION IS TO PROVIDE THE STAFF AND FACILITIES REQUIRED TO ENABLE ORTHOPEDIC FACULTY, RESIDENTS AND FELLOWS TO ACHIEVE NATIONAL AND INTERNATIONAL PROMINENCE THROUGH APPLIED RESEARCH OF THE VERY HIGHEST STANDARD. 5 5 25 15 0 0 600000 850000 307577 422957 12020 800 99383 1091 1018980 1274848 0 0 0 0 735210 879994 0 0 0 394886 459845 1130096 1339839 -111116 -64991 323970 275138 0 16159 323970 258979 X IORE'S FUNDAMENTAL RESEARCH MISSION IS TO PROVIDE THE STAFF AND FACILITIES REQUIRED TO ENABLE ORTHOPEDIC FACULTY, RESIDENTS AND FELLOWS TO ACHIEVE NATIONAL AND INTERNATIONAL PROMINENCE THROUGH APPLIED RESEARCH OF THE VERY HIGHEST STANDARD. 0 0 133959 97418 BAYLOR COLLEGE OF MEDICINE: POST-GRADUATE RESEARCH PROJECTS IN SPORTS MEDICINE.DURING THE 2012, IORE SUPPORTED ACADEMIC RESEARCH PROJECTS COMPLETED BY POST-GRADUATE SPORTS MEDICINE FELLOWS FROM BAYLOR COLLEGE OF MEDICINE. THESE PROJECTS RANGED FROM CADAVERIC STUDIES SIMULATING MUSCULO-SKELETAL FUNCTION TO COMPUTER SIMULATION OF THE RESULTS OF SURGICAL PROCEDURES. TYPICAL RESEARCH STUDIES INCLUDED:WE WORKED WITH A POST-GRADUATE FELLOW IN SPORTS MEDICINE TO INVESTIGATE THE MOTION OF REPAIRED TEARS WITHIN THE KNEE MENISCUS UNDER SIMULATED WEIGHT-BEARING CONDITIONS IN CADAVERS. AN EXPERIMENTAL METHOD WAS DEVELOPED IN WHICH MINIATURE SPHERICAL METAL BEADS WERE IMPLANTED IN THE MENISCUS AND TRACKED USING BIPLANAR RADIOSTEREOMETRY. THIS ALLOWED MOTION WITHIN THE SUBSTANCE OF THE MENISCAL TISSUE TO BE MEASURED IN THE INTACT CONDITION, AND AFTER REPAIR OF AN EXPERIMENTALLY-GENERATED TEAR. WE STUDIED THE EFFECT OF ALTERNATIVE METHODS OF PLACEMENT OF LIGAMENT GRAFTS WITHIN THE KNEE FOR REPLACEMENT OF THE INJURED ANTERIOR CRUCIATE LIGAMENT. THE EFFECTS OF THE PRECISE LOCATION OF THE POINTS OF GRAFT ATTACHMENT TO THE FEMUR AND TIBIA WERE SYSTEMATICALLY STUDIED IN TERMS OF THE STABILITY OF THE KNEE DURING ROTATORY ACTIVITIES AND THE MOTION OF THE BONES AND LOADING OF THE MENISCI.WE SIMULATED THE MOTION OF THE HIP JOINT USING COMPUTER RECONSTRUCTIONS OF THE FEMUR AND THE PELVIS AND THEN INVESTIGATED FACTORS CAUSING REDUCTION OF THE INNATE MOTION OF THE HIP IN INTERNAL ROTATION AND FLEXION. THE EFFECT OF RESCULPTING THE HEAD-NECK JUNCTION OF THE FEMUR WAS ASSESSED IN TERMS OF THE IMPROVEMENT IN JOINT MOTION RESULTING FROM REMOVAL OF UP TO 2, 4, AND 6MM OF BONE FROM THE ANTERIOR HEAD-NECK JUNCTION. WE DEVELOPED A CADAVERIC MODEL OF THE SHOULDER FOR PERFORMING ROTATOR CUFF REPAIRS AND THEN EXAMINED THE EFFECT OF AUGMENTING THE REPAIR WITH THE BICEPS TENDON. THE EFFECT OF AUGMENTATION WAS ASSESSED BY MEASURING THE STRENGTH OF EXPERIMENTAL REPAIRS AND THE CONTACT AREA BETWEEN HARD AND SOFT TISSUES IN 7 PAIRS OF CADAVERIC SHOULDERS. SPECIMENS WERE LOADED TO FAILURE USING AN INCREMENTAL LOADING PROTOCOL WHICH ALLOWED US TO MEASURE THE LOADS NEEDED TO GENERATE GAPS OF 3MM, 4MM, AND 5MM BETWEEN THE REATTACHED TENDON AND THE UNDERLYING BONE. 92034 FUNDAMENTAL INVESTIGATIONS OF THE LUBRICATION MECHANISMS OF THE HUMAN HIP JOINTIORE EMBARKED UPON A RESEARCH PROGRAM INVESTIGATING A POSTULATED MECHANISM FOR THE DEVELOPMENT OF OSTEOARTHRITIS OF THE HIP. RECENT CLINICAL AND EXPERIMENTAL STUDIES IN SWITZERLAND AND OTHER CENTERS HAVE SUGGESTED THAT CRIPPLING HIP ARTHRITIS IS THE END RESULT OF A SERIES OF EVENTS STARTING WITH ABNORMALITIES IN THE MORPHOLOGY OF THE FEMUR AND THE PELVIS, LEADING TO DAMAGE TO CRITICAL SOFT TISSUES LINING THE JOINT, AND EVENTUALLY LEADING TO CHANGES WITHIN THE LUBRICATION OF THE CARTILAGE OF THE JOINT, AND ULTIMATELY, OSTEOARTHRITIS. PART OF THIS PATHWAY INVOLVES THE CONNECTION BETWEEN THE STRUCTURE OF THE HIP JOINT AND THE FLUID TRANSPORT IN AND OUT OF THE JOINT WHICH IS ESSENTIAL TO KEEP CARTILAGE HEALTHY. HOWEVER, LITTLE IS KNOWN ABOUT HOW THIS OCCURS AND HOW INJURY TO THE JOINT MAY LEAD TO DETRIMENTAL CHANGES. TO INVESTIGATE THESE QUESTIONS , A TEAM OF IORE RESEARCH STAFF, INCLUDING A POST-DOCTORAL FELLOW, DEVELOPED A CADAVERIC MODEL OF THE HUMAN HIP JOINT WITH THE SEALING STRUCTURES OF THE HEALTHY JOINT FULLY PERSEVERED. EXPERIMENTAL METHODS WERE DEVELOPED TO MEASURE THE FLUID PRESSURES DEVELOPED WITHIN THE INNER AND OUTER COMPARTMENTS OF THE HIP DURING A BATTERY OF SPORTING ACTIVITIES, INCLUDING SEQUENTIAL STAGES OF GAIT, STOOPING, AND PIVOTING. DURING TESTING, THE 3D MOTION OF THE FEMORAL HEAD IN THE ACETABULUM WAS MEASURED WITH MOTION ANALYSIS COMBINED WITH COMPUTER VISUALIZATION. THIS WORK DEMONSTRATED THAT THE SEALING FUNCTION OF THE TISSUES OF THE HIP VARIES WITH HIP DISEASE AND JOINT POSITION AND IS NOT PRESENT IN SOME POSTURES COMMONLY ASSOCIATED WITH EARLY DEGENERATION OF THE JOINT. THIS WORK IS ONGOING. 164845 99637 METHODIST-CORNELL POST-GRADUATE RESEARCH PROJECTS IN JOINT REPLACEMENT.ORTHOPEDIC SURGEONS AFFILIATED WITH IORE HAVE A FUNDAMENTAL INTEREST IN THE OUTCOME OF SURGICAL PROCEDURES AND WAYS TO IMPROVE THE ACCURACY AND RELIABILITY OF THESE PROCEDURES. TOTAL KNEE REPLACEMENT IS A CASE IN POINT. ALTHOUGH THIS OPERATION IS ONE OF THE MOST COMMONLY PERFORMED IN ORTHOPEDICS, AND ONE OF THE MOST SUCCESSFUL FOR ELIMINATING CRIPPLING JOINT PAIN, FULL FUNCTION OF THE KNEE IS GENERALLY NOT COMPLETELY RESTORED, AND A SIGNIFICANT PROPORTION OF PATIENTS HAVE SOME MILD RESIDUAL SYMPTOMS, INCLUDING PAIN, SWELLING AND STIFFNESS. ALTHOUGH MANY FACTORS CONTRIBUTE, A FREQUENT CAUSE IS MALPOSITIONING OF THE TIBIAL AND/OR FEMORAL COMPONENTS COMPARED TO THE SURFACES OF THE ORIGINAL JOINT PRIOR TO THE ONSET OF DEGENERATIVE DISEASE. ANOTHER FACTOR IS THE DESIGN OF THE ACTUAL IMPLANT ITSELF IN COMPARISON WITH THE SHAPE OF THE BONES OF THE KNEE AND THE PROPERTIES OF THE SOFT TISSUES IN PROVIDING STABILITY DURING KNEE MOTION. IN EXPLORING TOPICS RELATED TO THIS THEME, WE PERFORMED THE FOLLOWING STUDIES AS PART OF THE TRAINING OF POST-GRADUATE FELLOWS WORKING IN JOINT REPLACEMENT AT HOUSTON METHODIST HOSPITAL IN THE TEXAS MEDICAL CENTER:AN INVESTIGATION OF THE CONSEQUENCES OF DIFFERENT STRATEGIES FOR PLACEMENT OF THE TIBIAL COMPONENT ON THE PREPARED SURFACE OF THE PROXIMAL TIBIAL DURING TOTAL KNEE REPLACEMENT PROCEDURES.THE ACCURACY AND REPRODUCIBILITY OF ALTERNATIVE ANATOMIC LANDMARKS FOR GUIDING THE POSITIONING OF THE TIBIAL COMPONENT IN TOTAL KNEE REPLACEMENT.THE EFFECT OF IMPLANT DESIGN ON THE STABILITY OF THE KNEE DURING A HIGH DEMAND ACTIVITY, SPECIFICALLY DESCENDING STAIRS. 492720 225902 OTHER ORTHOPEDIC RESEARCH PROJECTS. 492720 225902 883558 1 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 8 0 1 25 1 0 0 0 0 0 0 0 0 0 0 X 5 5 0 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 1 0 X X KIM MCCONN 7136104270 6550 FANNIN STREET SUITE 2512 HOUSTON TX 77030 X WILLIAM J BRYAN MD 0.50 X 0 0 0 BRADLEY WEINER MD 1.00 X X 0 0 0 JAMES R BOCELL MD 1.00 X X 0 0 0 KENNETH B MATHIS MD 1.00 X 0 0 0 STEPHEN INCAVO MD 0.50 X 0 0 0 0 0 0 0 0 0 0 0 850000 850000 RESEARCH SERVICES 541700 422957 422957 422957 800 800 651 651 MISCELLANEOUS 900099 440 440 440 1274848 422957 0 1891 712400 525360 187040 37390 27573 9817 77262 56977 20285 52942 39042 13900 41200 41200 2389 2389 2670 2670 5107 2106 3001 118 118 59754 48374 11380 30565 20078 10487 19847 19847 77595 77595 SUPPLIES 146892 127948 18944 SERVICES 28413 17887 10526 MEALS & ENTERTAINMENT 16570 158 16412 REPAIRS 10790 10750 40 17935 4916 13019 1339839 883558 456281 0 119913 116624 26561 0 51750 41800 532227 415513 125746 116714 323970 275138 0 16159 0 16159 X 0 0 0 0 323970 258979 323970 258979 323970 275138 -64991 0 X 0 0 0 X 615000 150000 600000 850000 2215000 546187 1190936 595087 307577 422957 3062744 1161187 1190936 745087 907577 1272957 5277744 0 236529 556910 196904 151626 1141969 236529 556910 196904 151626 1141969 4135775 9538 104991 86768 109603 1451 312351 9538 104991 86768 109603 1451 312351 1734 1800 440 3974 1170725 1295927 833589 1018980 1274848 5594069 0.73930 0.65040 0.05580 0.06500 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 90000 30097 59903 442227 385416 56811 116714 FORM 990, PART VI, SECTION B, LINE 11 A COPY OF THE 990 IS PROVIDED TO THE ORGANIZATION'S GOVERNING BODY BEFORE IT IS FILED. FORM 990, PART VI, SECTION B, LINE 12C THE BOARD REGULARLY AND CONSISTENTLY MONITORS AND ENFORCES THE COMPLIANCE WITH THE CONFLICT OF INTEREST POLICY BY OVERSEEING THE OPERATIONS OF THE ORGANIZATION. FORM 990, PART VI, SECTION B, LINE 15 THE PROCESS FOR DETERMINING COMPENSATION INCLUDES A REVIEW AND APPROVAL OF THE BOARD, COMPARABILITY DATA, AND CONTEMPORANEOUS SUBSTANTIATION. FORM 990, PART VI, SECTION C, LINE 19 THE ORGANIZATION MAKES ITS GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY, AND FINANCIAL STATEMENTS AVAILABLE TO THE PUBLIC UPON REQUEST. 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