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        <ProgramServices>37300</ProgramServices>
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      <GrantsToDomesticIndividuals>
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      <ForeignGrants>
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      </ForeignGrants>
      <BenefitsToMembers>
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        <ManagementAndGeneral>77004</ManagementAndGeneral>
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      <OtherExpenses>
        <Description>RESEARCH EXPENDITURES</Description>
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      <OtherExpenses>
        <Description>REPAIRS AND MAINTENANCE</Description>
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      <AllOtherExpenses>
        <Total>357125</Total>
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      <FSAudited>true</FSAudited>
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      <FederalGrantAuditPerformed>true</FederalGrantAuditPerformed>
    </IRS990>
    <IRS990ScheduleA documentId="IRS990ScheduleA">
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      <HospitalNameAndAddress>
        <Name>
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        </Name>
        <City>Pittsburgh</City>
        <State>PA</State>
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          <State>RESTRICTED</State>
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        <AffiliatedGroupTotals>0</AffiliatedGroupTotals>
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      <TotalDirectLobbying>
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      <TotalLobbyingExpenditures>
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      <TotalExemptPurposeExpenditures>
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        <CurrentYear>1000000</CurrentYear>
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        <CurrentYearMinus2>418483</CurrentYearMinus2>
        <CurrentYearMinus1>424588</CurrentYearMinus1>
        <CurrentYear>225684</CurrentYear>
        <Total>1653857</Total>
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      <GrassrootsNontaxableAmount2>
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        <CurrentYearMinus2>250000</CurrentYearMinus2>
        <CurrentYearMinus1>250000</CurrentYearMinus1>
        <CurrentYear>250000</CurrentYear>
        <Total>1000000</Total>
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      <GrassrootsCeilingAmount>1500000</GrassrootsCeilingAmount>
      <GrassrootsLobbyingExpenditures>
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        <CurrentYearMinus2>0</CurrentYearMinus2>
        <CurrentYearMinus1>0</CurrentYearMinus1>
        <CurrentYear>0</CurrentYear>
        <Total>0</Total>
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      <Form990ScheduleCPartIV>
        <Identifier>Election Under IRC Section 501(h)</Identifier>
        <ReturnReference>Schedule C, Page 2, Part II-A</ReturnReference>
        <Explanation>Allegheny Singer Research Institute (ASRI) has made the IRC Section 501(h) election. ASRI has not made any political expenditure and no direct lobbying expenditures. ASRI is a member of the West Penn Allegheny Health System (WPAHS). WPAHS employs an Executive Vice President for External Affairs to lobby issues of importance to WPAHS and all of its members. WPAHS also elected to engage the services of outside consultants to assist us in lobbying issues of importance. The lobbying expenditures of $3,315 attributed to ASRI on Schedule C, Page 2, Part II-A reflect expenditures allocated to ASRI from WPAHS and do not reflect direct expenditures made by ASRI.</Explanation>
      </Form990ScheduleCPartIV>
    </IRS990ScheduleC>
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        <Contributions>72446</Contributions>
        <InvestmentEarningsOrLosses>-59574</InvestmentEarningsOrLosses>
        <OtherExpenditures>105216</OtherExpenditures>
        <AdministrativeExpenses>24229</AdministrativeExpenses>
        <EndOfYearBalance>9686344</EndOfYearBalance>
      </CurrentYear>
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        <Contributions>76610</Contributions>
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        <OtherExpenditures>557204</OtherExpenditures>
        <AdministrativeExpenses>23076</AdministrativeExpenses>
        <EndOfYearBalance>9802917</EndOfYearBalance>
      </CurrentYearMinus1Year>
      <CurrentYearMinus2Years>
        <BeginningOfYearBalance>10029118</BeginningOfYearBalance>
        <Contributions>307611</Contributions>
        <InvestmentEarningsOrLosses>597003</InvestmentEarningsOrLosses>
        <OtherExpenditures>1129262</OtherExpenditures>
        <AdministrativeExpenses>33679</AdministrativeExpenses>
        <EndOfYearBalance>9770791</EndOfYearBalance>
      </CurrentYearMinus2Years>
      <CurrentYearMinus3Years>
        <BeginningOfYearBalance>9786888</BeginningOfYearBalance>
        <Contributions>97987</Contributions>
        <InvestmentEarningsOrLosses>235154</InvestmentEarningsOrLosses>
        <OtherExpenditures>68903</OtherExpenditures>
        <AdministrativeExpenses>22008</AdministrativeExpenses>
        <EndOfYearBalance>10029118</EndOfYearBalance>
      </CurrentYearMinus3Years>
      <PermanentEndowmentEOYBalance>0.80000</PermanentEndowmentEOYBalance>
      <TermEndowmentEOYBalance>0.20000</TermEndowmentEOYBalance>
      <EndowmentsHeldByUnrelatedOrgs>false</EndowmentsHeldByUnrelatedOrgs>
      <EndowmentsHeldByRelatedOrgs>false</EndowmentsHeldByRelatedOrgs>
      <Land />
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        <OtherCostOrOtherBasis>5984192</OtherCostOrOtherBasis>
        <Depreciation>5984192</Depreciation>
        <BookValue>0</BookValue>
      </Buildings>
      <LeaseholdImprovements>
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        <Depreciation>833870</Depreciation>
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      </LeaseholdImprovements>
      <Equipment>
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        <BookValue>410082</BookValue>
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      <FederalIncomeTaxLiability>0</FederalIncomeTaxLiability>
      <OtherLiabilities>
        <Description>ACCRUED PENSION COSTS</Description>
        <Amount>3525086</Amount>
      </OtherLiabilities>
      <OtherLiabilities>
        <Description>WORKERS COMPENSATION SELF INSURANCE</Description>
        <Amount>20655</Amount>
      </OtherLiabilities>
      <OtherLiabilities>
        <Description>GENERAL RESERVE</Description>
        <Amount>148415</Amount>
      </OtherLiabilities>
      <OtherLiabilities>
        <Description>DUE TO AFFILIATED ORGANIZATIONS</Description>
        <Amount>322709</Amount>
      </OtherLiabilities>
      <TotalOfAmounts>4016865</TotalOfAmounts>
      <Form990ScheduleDPartXIV>
        <Identifier>ASRI Inclusion In The Consolidated Audit of WPAHS</Identifier>
        <ReturnReference>Form 990, Schedule D, Part X Line 2, Part XII and XIII</ReturnReference>
        <Explanation>Allegheny Singer Research Institute (ASRI) does not issue independent audited financial statements. ASRI is a member of a regional healthcare system named West Penn Allegheny Health System. The West Penn Allegheny Health System receives a consolidated audit which includes the operations of ASRI. The following analysis represents the reconciliation between the financial statement net income and the net income as reported on Form 990, Page 1, line 19: Net loss per financial statements $ (8,929,867) Less: Income and expense reclassified from restricted net assets on the financial statements to unrestricted income and expense on Form 990 (11,357) ___________ Net income per Form 990 $ (8,941,224) The following is the footnote to the audited consolidated financial statements of the West Penn Allegheny Health System for FASB ASC 740: WPAHS adopted Financial Accounting Standards Board (FASB) Accounting Standards Codification (ASC) 740, Income Taxes, which clarifies the accounting for uncertainty in income taxes recognized in an enterprise's financial statements. FASB ASC 740 prescribes a more-likely than-not recognition threshold and measurement attribute for the financial statement recognition and measurement of a tax position taken or expected to be taken. Under FASB ASC 740, tax positions will be evaluated for recognition, derecognition, and measurement using consistent criteria and will provide more information about the uncertainty in income tax assets and liabilities. Based on an analysis prepared by WPAHS, it was determined that the application of FASB ASC 740 had no material effect on the recorded assets and liabilities of WPAHS.</Explanation>
      </Form990ScheduleDPartXIV>
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        <Identifier>Intended Use of the Organizations Endowment Funds</Identifier>
        <ReturnReference>Schedule D, Part V, Line 4</ReturnReference>
        <Explanation>The intended use of Allegheny Singer Research Institute's permanent and term endowments are for, but not exclusive to: capital improvements, research, education, departmental needs, operating efficiencies, and overall patient care. The earnings off of the permanent amount are expendable, based on the specific use of the fund.</Explanation>
      </Form990ScheduleDPartXIV>
    </IRS990ScheduleD>
    <IRS990ScheduleG documentId="IRS990ScheduleG">
      <EventsInformation>
        <NameOfEvent1>Big Blue Quest</NameOfEvent1>
        <GrossReceiptsEvent1>26784</GrossReceiptsEvent1>
        <CharitableContributionsEvent1>19089</CharitableContributionsEvent1>
        <GrossRevenueEvent1>7695</GrossRevenueEvent1>
        <NonCashPrizesEvent1>4268</NonCashPrizesEvent1>
        <RentFacilityCostsEvent1>5681</RentFacilityCostsEvent1>
        <OtherDirectExpensesEvent1>2931</OtherDirectExpensesEvent1>
        <TotalNumberOfOtherEvents>0</TotalNumberOfOtherEvents>
        <GrossReceiptsTotal>26784</GrossReceiptsTotal>
        <CharitableContributionsTotal>19089</CharitableContributionsTotal>
        <GrossRevenueTotalEvents>7695</GrossRevenueTotalEvents>
        <NonCashPrizesTotalEvents>4268</NonCashPrizesTotalEvents>
        <RentFacilityCostsTotalEvents>5681</RentFacilityCostsTotalEvents>
        <OtherDirectExpensesTotalEvents>2931</OtherDirectExpensesTotalEvents>
        <DirectExpenseSummaryEvents>12880</DirectExpenseSummaryEvents>
        <NetIncomeSummary>-5185</NetIncomeSummary>
      </EventsInformation>
      <Form990ScheduleGPartIV>
        <Identifier>Fundraising Event Net Income</Identifier>
        <ReturnReference>Schedule G, Part II, Line 11</ReturnReference>
        <Explanation>Allegheny Singer Research Institute conducted a fundraising event named the Big Blue Quest during the fiscal year. Schedule G, Part II, Line 11 reflects a loss on this event of $5,185. The reporting requirements dictate that we remove the charitable contribution portion of money received from the event to arrive at the figure on Line 11. In reality, the event raised $26,784 of total receipts. When the total receipts are netted against the event expense of $12,880, the result is a net gain of $13,904 from the event.</Explanation>
      </Form990ScheduleGPartIV>
    </IRS990ScheduleG>
    <IRS990ScheduleI documentId="IRS990ScheduleI">
      <RecordsMaintained>true</RecordsMaintained>
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        <RecipientNameBusiness>
          <BusinessNameLine1>Open Door Inc</BusinessNameLine1>
        </RecipientNameBusiness>
        <AddressUS>
          <AddressLine1>PO Box 99242</AddressLine1>
          <City>Pittsburgh</City>
          <State>PA</State>
          <ZIPCode>15233</ZIPCode>
        </AddressUS>
        <EINOfRecipient>300354607</EINOfRecipient>
        <IRCSection>501(c)(3)</IRCSection>
        <AmountOfCashGrant>20000</AmountOfCashGrant>
        <PurposeOfGrant>To further the charitable mission of the organization.</PurposeOfGrant>
      </RecipientTable>
      <RecipientTable>
        <RecipientNameBusiness>
          <BusinessNameLine1>Prevention Point Pittsburgh</BusinessNameLine1>
        </RecipientNameBusiness>
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          <AddressLine1>907 West Street 5th Floor</AddressLine1>
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          <State>PA</State>
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        <Identifier>Additional Compensation Disclosures</Identifier>
        <ReturnReference>Schedule J, Page 1, Line 4a</ReturnReference>
        <Explanation>Schedule J, Page 1, Line 4a: The following represents additional disclosure for Schedule J, line 4a pertaining to officers and key employees listed in Form 990, Part VII, Section A, Line 1a receiving severance pay during the calendar year ending within the June 30, 2012 fiscal year end: Christopher Olivia, MD $625,000 Dawn Gideon $520,867 Judy Hlafcsak $259,157 Thomas Albanesi $228,782 Diane Dismukes $166,673 Roy Santarella $117,174 Sanford Kurtz, MD $334,768 Schedule J, Page 1, Line 8: During the fiscal year ended June 30, 2012 Allegheny Singer Research Institute paid one individual compensation pursuant to a contract that was subject to the initial contract exeption described in Regulations section 53.4958-4(a)(3). Schedule J - General Explanation of Listed Individual Dates Served: The following list represents Officers, Directors, Key Employees and the 5 Highest Paid Employees of Allegheny Singer Research Institute listed on Form 990, Part VII who left the employment of Allegheny Singer Research Institute or an affiliated organization during the year ended June 30, 2012. The term of the service to Allegheny Singer Research Institute during the fiscal year ended June 30, 2012 is noted below: Diane Dismukes 07-01-2011 - 10-31-2011 Roy Santarella 07-01-2011 - 11-01-2011 David Kiehn 07-01-2011 - 12-30-2011 Deborah Olszewski 01-31-2012 - 06-30-2012 Matthew Peterson 01-31-2012 - 06-30-2012</Explanation>
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        <Identifier>Deferred Compensation</Identifier>
        <ReturnReference>Schedule J, Page 2, Column C</ReturnReference>
        <Explanation>Retirement and other deferred compensation reflect amounts accrued to the benefit of the applicable individuals related to qualified pension and severance plans. In this regard, the following individuals have amounts accrued related to future severance payments to be made: Christopher Olivia, MD Roy Santarella Judy Hlafcsak Thomas Albanesi Sanford Kurtz Diane Dismukes David Kiehn</Explanation>
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      <GeneralExplanation>
        <Identifier>Subsequent Event - Corporate Affiliation</Identifier>
        <ReturnReference>Form 990 - General Information</ReturnReference>
        <Explanation>West Penn Allegheny Health System, Inc., the sole member of Allegheny Singer Research Institute has consummated a formal affiliation on April 29, 2013 to establish a regional integrated health care services delivery system. The details of the affiliation are documented in the footnotes to the Audited Financial Statements attached to the IRS Form 990 of West Penn Allegheny Health System, Inc., EIN: 25-0969492. Please refer to the Audited Financial Statements for additional details.</Explanation>
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      <GeneralExplanation>
        <Identifier>Allegheny Singer Research Institute - Board Independence</Identifier>
        <ReturnReference>Form 990, Page 1, Part I, Line 4</ReturnReference>
        <Explanation>The appointment of the Allegheny Singer Research Institute Board of Directors is made by the sole member of the organization, West Penn Allegheny Health System, Inc. The Bylaws of Allegheny Singer Research Institute provides that the sole member has the exclusive power to fix the number of, and elect, appoint, fill vacancies in and remove, with or without cause, the Directors; and elect and remove, with or without cause, the Chair and Vice Chair of the Board of Directors of the Corporation, and the Secretary and Treasurer of the Corporation. The Board of Directors of the sole member of Allegheny Singer Research Institute is comprised of a majority of independent Board Members. The Board of Directors of Allegheny Singer Research Institute consists of two members who have voting rights on matters pertinent to the organization. Of these two members, none are deemed to be independent to the organization. Because of the independence of the Board of Directors of the sole member, and the rights and powers of the sole member to appoint and fix the Board of Directors of Allegheny Singer Research Institute, we deem that the Board of Directors of Allegheny Singer Research Institute is in fact controlled by a majority of independent Board Members.</Explanation>
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      <GeneralExplanation>
        <Identifier>Statement of Program Service Accomplishments</Identifier>
        <ReturnReference>Form 990, Page 2, Part III, Line 4a</ReturnReference>
        <Explanation>INRODUCTION TO ALLEGHENY SINGER RESEARCH INSTITUTE (ASRI) ASRI is part of the West Penn Allegheny Health System (WPAHS). Organized in 2000, WPAHS (www.wpahs.org) is comprised of West Penn Allegheny Health System, Inc. (WPAHS, Inc.), Alle-Kiski Medical Center (AKMC), Canonsburg General Hospital (CGH), Allegheny Specialty Practice Network (ASPN), Allegheny Medical Practice Network (AMPN), West Penn Physician Practice Network (WPPPN), West Penn Allegheny Oncology Network (WPAON), Canonsburg General Hospital Ambulance Service, Inc. (CGH Ambulance), Alle-Kiski Medical Center Trust (AKMC Trust), Forbes Health Foundation (FHF) and The Western Pennsylvania Hospital Foundation (WPHF). ASRI was established in 1977 as a Pennsylvania non-profit 501(c)(3) corporation and functions as the entity through which research at WPAHS, Inc. - Allegheny General Hospital (AGH), is conducted. Both ASRI and AGH are located in Pittsburgh, PA. ASRI has a distinguished history of pioneering biomedical research. Its leaders have recognized that through innovative research, ASRI can improve the quality of healthcare. Through its research efforts, ASRI has had a profound impact on many breakthroughs in innovative technology and research, including Pennsylvania's first heart-valve replacement and one of the first heart transplant procedures performed in the United States. This innovative environment continued with the performance of the nation's first bilateral ventricular assist, the first percutaneous automated discectomy, and the nation's first dynamic cardiomyoplasty (muscle flap procedure). ASRI was one of 10 U.S. medical centers to study drugs to reduce damage from spinal cord injuries. The ASRI Center for Genomic Sciences became the first in the world to map the gene for gastroesophageal reflux disease in children. ASRI is in a unique position to lead translational research that will improve patient care at a rapid pace. ASRI is focused on research that transfers innovation from the laboratory bench to the bedside so that patient care is advanced at a much more rapid pace than conventional research efforts. To accomplish this, ASRI has positioned its research culture uniquely at the midway point between an academic health center and the health-care industry, thus leveraging the strengths of both. MISSION, VISION &amp; VALUES The vision for ASRI is to facilitate advancement of basic and clinical research. ASRI's mission is to sponsor superior programs in health, education, and research and to fully integrate medical education and biomedical research in its clinical settings in order to continuously improve the patient care rendered, while containing costs to the community. COMMUNITY ASSESSMENT ASRI provides its community benefit through the cutting-edge technology and research it develops. Results of this type of research are ultimately felt by the local community in which ASRI is located and is served by WPAHS. ASRI provided this benefit at an estimated cost of $588,653. ASRI facilities are also home to a wide spectrum of biochemical, physiological and medical device research and development projects. With hundreds of active research projects in progress, the following represents a sample of the research and innovative solutions currently in process at ASRI: Stem Cell Transplantation - Cancer remains a formidable foe and kills more than 560,000 Americans each year. ASRI researchers are developing and testing novel therapies that could save more lives and even lead to cures. Of all the newer therapies being developed, stem cell transplantation, using stem cells from a patient's own body (autologous stem cell transplant) or stem cells from a donor (allogeneic stem cell transplant), is allowing oncologists to improve survival rates for cancer patients. ASRI researchers are conducting a landmark trial to assess the safety and efficacy of a treatment for hematological malignancies, including leukemia and lymphoma, in a global study. The study involves a graft of expanded stem/progenitor cells, derived from a single unit of umbilical cord blood and transplanted in combination with non-expanded cells from the same unit. Sublingual Immunotherapy - Pediatric researchers at ASRI are involved in several Phase III clinical trials testing sublingual immunotherapy, a method of allergy treatment that uses an allergen solution under the tongue. The allergen interacts with the immune system and changes the body's ability to react to allergens. Popular in Europe for many years, sublingual immunotherapy is beginning to gain interest in the United States as a more tolerable allergy management option when compared to injection immunotherapy. Typically, a person has to get allergy shots for 3 to 5 years to become tolerant to an allergen. Since allergy shots can be a traumatic experience for a pre-school child, it is not surprising that many parents discontinue treatment, putting their children at greater risk for developing bothersome allergies later in life. This new form of treatment may encourage more parents to start their children on allergy therapy. In addition, ASRI researchers are testing the effectiveness of an asthma medication in reducing the severity and length of the common cold, as well as testing a new vaccine that could prevent RSV, or the respiratory syncytial virus. Researchers also continue to test new medications for the treatment of allergy and asthma in both adults and children. Bioremediation Technologies - With estimated reserves of over 500 trillion cubic feet of natural gas, the Marcellus Shale has the potential to fulfill America's natural gas needs for years to come. One of the major challenges in manufacturing this natural resource is disposing of millions of gallons of contaminated waste water used in the shale fracturing process. Researchers from ASRI are developing and commercializing a customized suite of biofilm-based bioremediation technologies that will not only decontaminate the waste water, but also make it available for recycling. These bioremediation technologies could also be applied to acid rock drainage (ARD) - providing an on-site biofilm-based bioremediation system to remove heavy metals from frac water, as well as using biofilms to remediate ARD. The Positive Health Clinic - The Positive Health Clinic provides HIV education, prevention, testing and treatment to countless individuals. During 2012 the ASRI Clinic, which is only one of two such locations serving residents of Southwest Pennsylvania, provided one or more services to over 780 individuals, the majority of whom are infected with HIV. All services were provided regardless of their ability to pay. The Clinic provides a holistic approach to HIV education, prevention and care, often providing services that are not covered by insurance such as transportation to appointments, social workers, mental health therapists and psychiatric care. The Clinic provides services to all who seek them, approximately 21% of whom are uninsured. ASRI receives federal funding for its HIV patient screening and care initiatives through the Ryan White Program. The Ryan White Comprehensive AIDS Resources Emergency (CARE) Act (Ryan White CARE Act, Ryan White, Pub.L. 101-381, 104 Stat. 576, enacted August 18, 1990) is the United States' largest federally funded program for people living with HIV/AIDS. The act sought funding to improve availability of care for low-income, uninsured and under-insured victims of AIDS and their families. It funds heavily impacted metropolitan areas, states, and local community-based organizations to provide life-saving medical care, medications, and support services to more than half a million people each year. In relation to this program, ASRI participated in the following activities at no cost to the participants: Community HIV testing and counseling in the clinic and at Light of Life Shelter, support for local AIDS Service Organizations (ASO's) including the Open Door Housing Program, The Pittsburgh AIDS Task Force, The Persad Center, The Shepherd Wellness Community and the Beaver County Project Hope. The Positive Health Clinic participated in HIV education and outreach for Allegheny community College (northside campus), Pittsburgh Pride, and the House of Infinity Balls. The clinic supports a women's empowerment group that meets two time a year and a bi-weekly HIV support group.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Statement of Program Service Accomplishments - Continued</Identifier>
        <ReturnReference>Form 990, Page 2, Part III, Line 4a</ReturnReference>
        <Explanation>SciTech Exhibit - SciTech is an event that is presented by the Carnegie Science Center to inspire interest in science and technology among high school and middle school students. Our goal is to engage with SciTech visitors and share research conducted at ASRI and the biomedical application within WPAHS. During SciTech, students also learn about the diverse range of careers available within the allied health fields. The scientists, physicians and nurses who participate in the exhibit have been very enthusiastic and have succeeded in putting a professional and personal face on ASRI and WPAHS for science educators and students as well as the general public. Science and health educators also benefit as they learn cutting edge research and field trip opportunities to our facilities. Over 6000 teachers and students attended the SciTech Event last year. We believe that educational outreach programs such as SciTech are an important venue for informing the Greater Pittsburgh area about ASRI's vision to advance basic, translational and clinical research in concert with the clinical strengths of WPAHS. In the past we have had a very successful exhibit and an excellent response. Last year we featured the Gerald McGinnis Cardiovascular Institute, The Comprehensive Stroke Center, The Lupus Center of Excellence, Radiation Oncology, Pharmacy, and Nursing Education as well as research centers such as the Center for Neurosciences Research, Simulation, Teaching, and Academic Research Center (STAR), Orthopaedic Surgery Biomechanics Laboratory, and the Center for Genomic Sciences. SciTech has recruited talented high school students for research internships and gives high school students the opportunity to watch a live open heart surgery at AGH. SciTech also provides a recruitment mechanism for area high school teachers to participate in a professional development project that we have funded through the U.S. Department of Education. Finally, it also enlightens people about AGH's long-standing role in research. Pittsburgh Regional Science and Engineering Fair - The Pittsburgh Regional Science and Engineering Fair celebrated its 73rd year of open competition of research projects in the fields of science, mathematics, and engineering in 2012. ASRI is a Silver Sponsor of this event and appoints employees to judge the fair and distribute awards. This competition is open to all students in grades 6-12 from the 26 counties within Western Pennsylvania and West Virginia. The Science Fair has been a Pittsburgh tradition since 1940. It is also the third oldest science fair in the United States under the affiliation of Society for Science and the Public, which facilitates the International Science and Engineering Fair. The Science Fair has become the venue to connect bright and motivated young scientists with this region's industry, academia, and professional organizations like ASRI to promote economic development within Western Pennsylvania. Introducing students to the science and technology opportunities within our region will facilitate the cultivation and retention of a tremendous resource-our youth. In 2012, more than 1,100 students from 120 schools competed for $1M in cash prizes, scholarships and trips. The 2012 Science Fair was co-sponsored by various foundations, universities, colleges, industries, corporations, and professional societies including ASRI. Months before the Science Fair, the students develop a project by utilizing the scientific method. ASRI makes suggestions at the beginning of the school year for topics that are of interest (e.g., stroke, cardiovascular system, etc.). Students may choose one of these topics to focus their project. At the Science Fair, they exhibit their research on a presentation board and are interviewed by judges who consist of the area's most distinguished scientists and engineers including those from ASRI. The next day, an award ceremony is held honoring the participants and winners of the Science Fair. National Surgical Adjuvant Breast and Bowel Project - NASRI is the host campus for the National Surgical Adjuvant Breast and Bowel Project (NSABP) where advancements have dramatically altered the standard treatment for breast cancer, and where efforts are now being applied to prevention trials. The Center for Genomic Sciences is pioneering work with biofilms; germ communities that are responsible for scores of diseases and many hospital-acquired infections. The Center for Neuroscience Research continues to expand upon its groundbreaking work in deep brain stimulation and post-stroke epilepsy. In Cardiology they are developing groundbreaking treatments for pulmonary hypertension, drug resistant hypertension, myocardial infarction and other cardiovascular conditions. There are also studies being done that focusing on cardiac imaging which could result in earlier and more aggressive therapeutic intervention for patients with patients with risk for stroke or heart attack. The Disadvantaged Women's Program - The Allegheny Women's Biotechnology Workforce Collaborative (AWBWC) has brought together several large, neighborhood organizations with a small, localized group of disadvantaged women to address the economic, health and financial needs of a region, and more particularly, a community. The AWBWC provides a psychosocial educational intervention which builds both scientific and life-skills for these women. While working with a dedicated staff of case managers, social workers, academic tutors, mental healthcare providers, the women attend the Community College of Allegheny County (CCAC). This program incorporates the Associate's Degree program in Biotechnology with additional support through a learning community. The learning community meets weekly to develop strategies for behaviors which contribute to success in their personal lives and success in their future workplace. The AWBWC is comprised of local stakeholders in education, healthcare, research, civic organizations, philanthropy and potential Science, Technology, Engineering and Math, (STEM) employers. The training program has as its goal the training and career placement of disadvantaged women into the biotechnology workforce. Unlike other interventions, the foundation of the AWBWC is to develop an individualized approach to meet the specific needs of these women guided by a licensed clinical social worker and case manager. Additionally, they learn to navigate the existing resources available at the community college because historically they are apprehensive and uncomfortable dealing directly with institutions. The social worker directly advocates on behalf of the women in the learning community composed of educators and administrators. During their training, qualitative and quantitative data is captured on the participants, as well as on their children, with regard to both learning and social advancement. The qualitative data takes the format of weekly correspondence by email, text message and frequent face to face interviews. The quantitative data includes participant GPA and attrition rates. This family-based approach is designed to lift entire families out of poverty. These women and their children live at 60% below the poverty level and 100% have been victimized with manifestations of Post-Traumatic Stress Disorder (PTSD). The first class, includes not only the 12 enrollees, but over 20 children as well. The second class which received funding to compensate for tuition through a grant provided by the National Science Foundation includes 10 women and 18 children. Both cohorts are doing exceptionally well, experiencing less than 50% attrition while maintaining excellent grades. As of December 2011, 10 students graduated from the program and either gained employment or continued onto a bachelor's degree program. Initial self-reporting through a focus group suggests that the children are benefiting from a ripple effect and take pride in their mother's accomplishments, as well as performing better in school. We will follow up with children's teacher reports and quantitative evaluations of the children's academic performance to document any trickle-down effect. The graduates from this program are working in the biotech or healthcare industry at several different Pittsburgh area entities. ASRI provides total support for the social worker component of the program, with this position being responsible for recruitment and retention, providing intensive case management and counseling. ASRI continues to maintain dedicated lab space for the biotech students to practice their skills under the supervision of an ASRI scientist. FINANCIAL CONTRIBUTIONS ASRI supports the community through cash contributions made at the discretion of the entity, benefiting not only the non-profit recipient but ultimately the community as a whole. ASRI made the following cash contributions during Fiscal 2012 totaling $37,300: Open Door Inc. Prevention Point Pittsburgh</Explanation>
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      <GeneralExplanation>
        <Identifier>Operational Oversight By A Third Party Management Company</Identifier>
        <ReturnReference>Form 990, Page 6, Part VI, Section A, Line 3</ReturnReference>
        <Explanation>Allegheny Singer Research Institute (ASRI) is a member of the West Penn Allegheny Health System (System). The System consists of thirteen operational IRC Section 501(c)(3) organizations. The parent organization for ASRI and the other eleven operational IRC Section 501(c)(3) organizations is West Penn Allegheny Health System, Inc. (WPAHS, Inc.). The board of directors of WPAHS, Inc. is comprised of a majority of independent members. Effective November 7, 2011 (Effective Date), the board of directors of WPAHS, Inc. engaged Alvarez &amp; Marsal Healthcare Industry Group, LLC (A&amp;M) to assign an Interim Chief Executive Officer of the System, Interim Chief Operating Officer of the System and Interim Chief Financial Officer of the System. All individuals appointed to their respective positions are under the employment of A&amp;M and have daily oversight of all matters pertinent to the operation of the System as a whole and all organizations on an independent basis. All interim management personnel under the employment of A&amp;M are responsible to and report to the WPAHS, Inc. board of directors. The term of the engagement is to last one year from the effective date with the option to renew the engagement beyond the initial one year term. During the course of the engagement, the WPAHS, Inc. board of directors upon written notice may cause any individual employed by A&amp;M to be removed from their respective position and replaced by another similarly qualified individual. ASRI did not directly compensate A&amp;M for their management services. WPAHS, Inc. compensates A&amp;M directly for these services. The decision was made to allocate a portion of the expenditures of WPAHS, Inc. to ASRI. Thus, the portion of management expense allocated from WPAHS, Inc. to ASRI is reflected on Form 990, Page 10, Line 11a. As of the date of the filing of this tax return, A&amp;M continues to provide management oversight to ASRI and the System under the supervision of the WPAHS, Inc. board of directors.</Explanation>
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      <GeneralExplanation>
        <Identifier>Form 990 Review Process</Identifier>
        <ReturnReference>Form 990, Page 6, Part VI, Section B, Line 11a</ReturnReference>
        <Explanation>Form 990 is prepared internally by an employee of the West Penn Allegheny Health System, Inc. (Health System) Tax Department who is a certified public accountant. The document is then reviewed internally by top management officials of the Health System. A detailed external review is conducted by Health System external tax advisors, who sign the return as preparer. Members of the Audit and Compliance committee of the Health System Board review the Form 990 and recommend changes or accept the document as presented. A copy of the Form 990 is made available to every board member for review prior to filing the document with the Internal Revenue Service.</Explanation>
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      <GeneralExplanation>
        <Identifier>Monitoring and Enforcement of the Conflict of Interest Policy</Identifier>
        <ReturnReference>Form 990, Page 6, Part VI, Section B, Line 12c</ReturnReference>
        <Explanation>Allegheny Singer Research Institute is a member of the West Penn Allegheny Health System (WPAHS). WPAHS has a corporate compliance department that monitors and oversees compliance with the conflict of interest policy of all organizations in the health system. The following describes the manner in which the corporate compliance department monitors and oversees compliance with the conflict of interest policy for Allegheny Singer Research Institute as well as the other WPAHS affiliates: Conflict of Interest disclosure forms are completed on an annual basis by all board members, officers, employees who have a title of Manager and above, physicians in leadership roles, Pharmacy and Therapeutic Committee members, all employees of the System's Compliance and Internal Audit Departments as well as personnel involved with contracting in the Corporate Purchasing Department. Upon completion of the above disclosure statement by all applicable individuals, a report is generated listing all individuals that have reported a conflict. The System Compliance Officer and General Counsel review the conflicts disclosed. Those that require additional information or clarification receive a letter from the Compliance Officer requesting such. Once received, all additional information is added to the report and again reviewed by the Compliance Officer and General Counsel. Those conflicts that require a mitigation plan are sent to the respective organization's senior management for development of the mitigation plan. The organization's senior management is responsible to discuss the mitigation plan with the individual as needed and monitor compliance with the mitigation plan. Once mitigation is received, a final report is reviewed with the System Executive Compliance Council and finally the Audit &amp; Compliance Committee of the Board.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Executive Compensation Review Process</Identifier>
        <ReturnReference>Form 990, Page 6, Part VI, Section B, Line 15b</ReturnReference>
        <Explanation>The West Penn Allegheny Health Systems (WPAHS) process for determining compensation for executive positions (including officers, key employees and other management positions) within Allegheny Singer Research Institute is covered by the WPAHS Executive Compensation Policy. This policy was approved by the West Penn Allegheny Health System, Inc. Board of Directors. It is the policy of WPAHS and its Board of Directors to compensate its executives in accordance with the market and in relation to the experience, service and accomplishments of the individual both prior to and during their service with WPAHS. The Compensation Committee of the West Penn Allegheny Health System, Inc. Board of Directors approves the compensation for WPAHS senior executives. The Compensation Committee approves the initial compensation for newly hired senior executives, which shall include all compensation components, including without limitation, base compensation, incentive compensation, deferred compensation, fringe and other benefits, as well as the total compensation. It shall also approve all base compensation adjustments and all incentive compensation awards, as well as material changes to deferred compensation, fringe, or other benefits. The Compensation Committee uses comparability data provided by the System Human Resources Department, which may include industry surveys, expert compensation studies, documented compensation of persons holding similar positions, or other comparable data in approving any executive compensation. The Compensation Committee shall periodically retain the services of an independent compensation consultant to provide an expert opinion report as to the reasonableness of total compensation of Allegheny Singer Research Institute officers and key employees. Each Compensation Committee member voting on a senior executive's compensation arrangement ensures that he or she has no conflict of interest, including that he or she (a) does not economically benefit from the proposed employment; (b) does not receive compensation subject to the approval of the proposed employee; and (c) has no material financial interest affected by the transaction. The Compensation Committee consists of five independent Board Members of West Penn Allegheny Health System, Inc. All decisions of the Compensation Committee regarding executive compensation matters are documented.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Public Access To Organizational Documents</Identifier>
        <ReturnReference>Form 990, Page 6, Part VI, Section C, Line 19</ReturnReference>
        <Explanation>Allegheny Singer Research Institute (ASRI) does not make its governing documents available to the public. ASRI is a member of the West Penn Allegheny Health System (WPAHS). The WPAHS makes available their annual and quarterly financial statements through the use of a dissemination agent. These financial statements are on a consolidated basis with ASRI being one of the consolidated entities. In addition, the WPAHS annual report and quarterly financial results are available on the WPAHS website. WPAHS has adopted a conflict of interest policy that is uniformly applied to all organizations of the health system, including ASRI. A condensed version of this conflict of interest policy is available on the WPAHS website.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Officer, Director and Key Employee Hour Allocation</Identifier>
        <ReturnReference>Form 990, Page 7, Part VII, Section A, Column B</ReturnReference>
        <Explanation>Allegheny Singer Research Institute (ASRI) is part of an integrated healthcare delivery system named West Penn Allegheny Health System. Individuals employed by one organization may be assigned to provide management for an affiliated organization. As such, many individuals play key roles or serve as officers or directors on multiple affiliated organizations. Each individual will be assigned forty hours to the organization of their actual employment. If the individual is employed by one organization and appointed as an officer, director or key employee of affiliated organizations the hour allocation on Form 990, Part VII, Page 7, Column (B) takes various factors into account when attempting to assign hours in a reasonable manner. Thus, it is possible for a single individual to have hours assigned in excess of forty hours per week if all affiliated organization IRS Forms 990 is taken into account. The actual time served for all individuals disclosed in IRS Form 990 can vary based upon the need of the organization.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Rental Expense</Identifier>
        <ReturnReference>Form 990, Page 9, Part VIII, Line 6b</ReturnReference>
        <Explanation>Allegheny Singer Research Institute does not account for rental expense in a manner that would allow us to net the expense against the income on Form 990, Page 9, Line 6b. The rental expense is included as a component of the Statement of Functional Expense on Form 990, Page 10.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Health System Tax Exempt Bond Issuance</Identifier>
        <ReturnReference>Form 990, Page 11, Part X, Line 20</ReturnReference>
        <Explanation>Allegheny Singer Research Institute is a member of the West Penn Allegheny Health System obligated group in regards to 2007 Allegheny County Hospital Development Authority tax-exempt bonds. The purpose of the issue of the Allegheny County Hospital Development Authority (ACHDA) Hospital Revenue Bonds, Series 2007 A is to refund the outstanding ACHDA Series 2000A and B Bond Issues, refund the Dauphin County General Authority (DCGA) Series 1992A and B Hospital Bonds, the Pennsylvania Higher Education Facility Authority (PHEFA) Series 1991A Revenue Bonds, the Monroeville Hospital Authority (MHA) Series 1992 and 1995 Revenue Bonds, the funding of a project fund for certain prior and future capital expenditures and to pay the cost of issuing Series 2007A Debt. No internal allocation of debt has been made to Allegheny Singer Research Institute, however, the organization's assets are security for purposes of this bond issue.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>Other Changes In Net Assets</Identifier>
        <ReturnReference>Form 990, Page 12, Part XI, Line 5</ReturnReference>
        <Explanation>The following is a reconciliation of the Other Changes In Net Assets of Allegheny Singer Research Institute for the year ended June 30, 2012: Transfers From Affiliated Organizations $9,006,199 Unrealized Loss on Investments (103,512) Net Change in Minimum Pension Liability (1,283,303) __________ Other Changes In Net Assets $7,619,384</Explanation>
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          <Country>CJ</Country>
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        <Identifier>Transactions With Affiliated Organizations</Identifier>
        <ReturnReference>Schedule R, Part V, Line 2</ReturnReference>
        <Explanation>Allegheny Singer Research Institute has chosen not to complete Schedule R, Part V, line 2. The disclosure of this information is only required for organizations listed in Schedule R, Part V, line 2 that are controlled entities within the meaning of section 512(b)(13). No organization listed in Schedule R, Part V, line 2 is a controlled entity within the meaning of section 512(b)(13) for Allegheny Singer Research Institute.</Explanation>
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</Return>