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        <Explanation>Each director, office and key employee is annually provided with a copy of the Foundation's conflict of interest policy. Each of these individuals is annually provided with a questionnaire regarding potential conflicts and required to disclose any potential conflict that he or she might have. In addition, each of these individuals must annually sign a statement affirming that he or she has; received a copy of the conflicts of interest policy, read and understood the policy and agrees to comply with the policy. Once the Foundation has collected annual disclosure statements from all directors, officer and key employees, the Foundation's Governance committee review such information to identify situations in which a conflict exists and is material. If a material conflict is identified, the committee analyzes whether the contemplated transaction may be authorized as just, fair, and reasonable to the Foundation. The Governance Committee then makes a recommendation to the Foundations' Executive Committee regarding the management of all potential conflicts it has identified. The final decision as to the approval and , where applicable, management of all such potential conflicts rests in the sole discretion of the Executive Committee, which make such decisions based upon the welfare of the Foundation and the advancement of its purpose. The recommendations of the Governance Committee and decisions of the Executive Committee are documented in the respective minutes of these Committees' regular meetings.</Explanation>
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        <Explanation>Compensation for Officers is determined and evaluated in May of each year by leadership of the board of directors based on comparability data from widely accepted peer benchmarking salary surveys that are segmented by region and size of entity. Compensation for principal investigators (lead researchers), including any key employees, is determined by Foundation Officers based on the comparability data referenced above and evaluated in May of each year.</Explanation>
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        <Explanation>The Foundation's governing documents, conflicts of interest policy, and financial statements are provided upon request and are publicly available on the Foundation's website.</Explanation>
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        <ReturnReference>Form 990, Part XI, Line 5</ReturnReference>
        <Explanation>Includes decrease in fair value of funds held in trust by others, net investment losses in excess of gains (losses) designated for operations and pension related changes other than net periodic pension costs.</Explanation>
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