2013-08-14T13:22:06-07:00 2012-12-31 990 2012-01-01 236434390 THE WISTAR INSTITUTE OF ANATOMY & BIOLOGY WIST 2158989910 3601 Spruce Street Philadelphia PA 191044265 Alan Stiles 2158983742 2013-08-14 2012 2016-02-25 16:41:14Z Alan Stiles 3601 Spruce Street Philadelphia PA 191044265 97600000 0 X www.wistar.org X 1892 PA Biomedical research with special expertise in cancer research and vaccine development 33 33 362 11 52000 -49000 68019000 47565000 1526000 1693000 4061000 2242000 18705000 15924000 92311000 67424000 0 0 0 0 29496000 30151000 0 0 722000 30565000 31921000 60061000 62072000 32250000 5352000 159446000 193555000 27404000 50741000 132042000 142814000 Founded in 1892 as the first independent nonprofit biomedical research institute in the counrty, Wistar has long held the prestigious Cancer Center designation from the National Cancer Institute. Multidisclipinary research at The Wistar Institute focuses on the molecular and cellular bases of cancer, autoimmune disorders, several age-associated disorders and other serious illnesses. The Wistar Institute is dedicated to basic biomedical research-investigation driven by the desire of Wistar researchers to answer fundamental scientific questions. Throughout its history, the ability of Wistar scientists to explore their research interests has yielded new therapies, vaccines, and insights that have profoundly influenced the progress of both science and medicine. Wistar scientists are international leaders in their fields, defining the questions that must be asked and devising the tools needed to answer those questions. 0 0 49262000 0 1693000 CANCER RESEARCH - The Wistar Institute Cancer Center has a history of significant advances in cancer genetics, cancer biology, tumor biology, and virology and merges basic cancer research with translational advances toward cancer prevention, diagnosis, and therapy. Cancer Center scientists conduct research on gene expression and regulation, molecular and cellular oncogenesis , and tumor microenvironment and metastasis. Deciphering cancer genetics: Wistar is a national leader in illuminating how mutations in genes lead to various cancers. Leading the fight against melanoma: Wistar oversees one of the most prestigious melanoma research programs in the world, studying the development of the disease and pursuing treatments for advanced melanoma. Stem cell investigations: Institute researchers are identifying and characterizing cancer stem cells that appears to be responsible for recurrent and treatment-resistant forms of cancer. Exploring the role of the tumor microenviornment: The tumor microenviornment involves the chemical conversations that occur between cancerous cells and the healthy cells that surround and support them. It is the tumor microenvironment that makes it possible for tumors to change from benign to malignant to metastatic. Targeting these cells could greatly increase the effectiveness of traditional anti-cancer treatments. 0 0 0 IMMUNOLOGY AND VIROLOGY - The Wistar Institute remains a world leader in advancing the scientific understanding of the immune system and its role in disease. Among its successes are vaccines against rabies, rubella and rotavirus, as well as patenting the method of producing monoclonal antibodies, a process that informs the development of many of today's targeted therapies. Working together to fight disease: Wistar researchers are collaborating with leading scientists worldwide to develop vaccines for hepatitis C, malaria, and other potentially deadly diseases. A global reach: The Institute has licensed its rabies and rubella vaccine seed stock to companies in China, India, and Russia to help these countries develop affordable vaccines for their own populations. Easing the pain: Wistar Immunologists also are developing novel therapies for autoimmune diseases such as lupus and rheumatoid arthritis. 0 0 0 TRAINING THE NEXT GENERATION OF SCIENTISTS - At the Wistar Institute, science and cancer education is our priority. Our educational and training programs cover the full spectrum from high school students and undergraduates to pre-doctoral candidates and post-doctoral researchers, with an emphasis on reaching underserved and minority populations. High School Programs: Wistar offers internships, tours, and essay contests to area high school students to stimulate and nurture their interests in science. Wistar's Summer Fellowship Program allows students to become directly involved in experimental biological research projects at the bench level. Students may work on active research projects in cancer genetics, control of tumor progression, and vaccine development. Biomedical Training Program: The Biomedical Technician Training Program prepares Community College of Philadelphia students for an exciting career in the growing field of basic and applied biomedical research. The program combines academic course work with specialized training in research laboratories at the Institute. This dual experience offers students seeking an associate's degree the opportunity to acquire the skills necessary to qualify for positions as technicians in biomedical research laboratories ususally only available to graduates of four-year baccalaurate programs. Postdoctoral Programs: Postdoctoral fellows come to The Wistar Institute to carry out research under the mentorship of one of the Institute's faculty members. The postdoctoral training program emphasizes research experience and takes advantage of the cooperative interactions among the participating faculty as well as seminar courses and speaker programs. Cancer Biology Graduate Program: The cancer biology graduate degree program-jointly administered by The Wistar Institute and University of the Sciences (USciences)-trains individuals with outstanding potential for a successful academic or industrial career in cancer biology and drug development. This Ph.D. program fills a reginal gap in specific training in cancer biology, and includes cutting-edge strategies in translational aspects, such as cancer prevention and therapy. 0 0 0 49262000 1 1 0 1 0 0 0 1 0 1 1 1 0 0 1 1 1 0 0 0 0 0 0 0 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0 1 1 1 0 0 0 0 1 1 1 0 0 1 95 0 1 362 1 1 1 0 0 0 0 1 1 0 0 0 0 X 33 33 1 0 0 0 0 1 0 1 1 0 0 1 1 1 1 1 1 1 1 0 CA FL NJ NY PA X Stephen E Tustin CPA 2154956887 3601 Spruce Street Philadelphia PA 191044265 Helen P Pudlin 3.00 0.00 X X 0 0 0 Richard Horowitz 3.00 0.00 X X 0 0 0 Maida Milone 2.00 0.00 X X 0 0 0 Seymour S Preston III 1.00 0.00 X X 0 0 0 Elizabeth McKee Anderson 1.00 0.00 X 0 0 0 Robert S Blank 1.00 0.00 X 0 0 0 Van Billet 1.00 0.00 X 0 0 0 Douglas D Briggs 1.00 0.00 X 0 0 0 Ira Brind 1.00 0.00 X 0 0 0 Ronald Caplan 2.00 0.00 X 0 0 0 Brian H Dovey 1.00 0.00 X 0 0 0 Daniel Fitzpatrick 1.00 0.00 X 0 0 0 Robert A Fox 2.00 0.00 X 0 0 0 Joseph A Goldblum 1.00 0.00 X 0 0 0 Herbert Kean MD 1.00 0.00 X 0 0 0 Faye Olivieri-Kozich 1.00 0.00 X 0 0 0 Susan S McDonald 2.00 0.00 X 0 0 0 Abraham L Morris 1.00 0.00 X 0 0 0 I Wistar Morris 1.00 0.00 X 0 0 0 Albert Ominsky Esq 1.00 0.00 X 0 0 0 Arthur M Pappas 1.00 0.00 X 0 0 0 Vincent Price PhD 1.00 0.00 X 0 0 0 Samuel V Rhoads 1.00 0.00 X 0 0 0 Robert H Rock 1.00 0.00 X 0 0 0 Gerald B Rorer 1.00 0.00 X 0 0 0 Adele K Schaeffer 1.00 0.00 X 0 0 0 Paul J Schmitt 1.00 0.00 X 0 0 0 Milton S Schneider 1.00 0.00 X 0 0 0 Judith Soltz Esq 1.00 0.00 X 0 0 0 Lawrence V Stein 1.00 0.00 X 0 0 0 David V Wachs 1.00 0.00 X 0 0 0 Daniel H Wheeler Esq 1.00 0.00 X 0 0 0 Edward Ziff PhD 1.00 0.00 X 0 0 0 Russel Kaufman MD 65.00 0.00 X 681000 0 43000 Dario Altieri 55.00 0 X 413000 0 46000 Alan Stiles 55.00 0.00 X 110000 0 17000 Larry Keinath 55.00 0 X 268000 0 43000 Elizabeth O'Brien 55.00 0 X 266000 0 58000 Peter Corrado 55.00 0 X 203000 0 47000 Meenhard Herlyn DVM 55.00 0 X 241000 0 54000 David Speicher PhD 55.00 0 X 238000 0 34000 Hildegund Ertl MD 55.00 0 X 229000 0 40000 Frank Rauscher PhD 55.00 0 X 214000 0 32000 Ellen Pure PhD 55.00 0 X 213000 0 40000 3076000 0 454000 46 0 1 0 L F Driscoll Co LLC 9 Presidential Blvd P O Box 468 Bala Cynwyd PA 19004 Construction Management 17041000 Ballinger 833 Chestnut Street Suite 1400 Philadelphia PA 19107 Architecture Engineering Planning Interior Design 837000 Laredo Mechanical LLC P O Box 250 Plymouth Meeting PA 19462 HVAC Services 658000 ABM Mid-Atlantic Inc 420 Feheley Drive King of Prussia PA 19406 Janitorial 422000 AlliedBarton Security Services 161 Washington Street Suite 600 Conshohocken PA 19428 Security services 333000 19 0 0 152000 0 33751000 13662000 6359000 47565000 Scientific Research 541700 1693000 1693000 0 0 0 0 0 0 1693000 947000 0 0 947000 0 0 0 0 15148000 0 0 15148000 0 0 31410000 0 30115000 0 1295000 0 1295000 0 0 1295000 31000 152000 61000 -30000 0 -30000 Other Investment Income 900099 754000 0 0 754000 Sale of Specialized Services 541700 52000 0 52000 0 0 0 0 0 806000 67424000 1693000 52000 18114000 2196000 470000 1726000 0 0 20119000 14698000 5084000 337000 2452000 1681000 734000 37000 4000000 2785000 1145000 70000 1384000 949000 414000 21000 314000 311000 3000 87000 87000 181000 181000 97000 97000 1745000 543000 1162000 40000 34000 29000 5000 436000 71000 354000 11000 662000 86000 565000 11000 5953000 166000 5787000 337000 221000 105000 11000 94000 72000 21000 1000 35000 35000 5940000 5940000 218000 218000 Subcontracts 8301000 8301000 0 0 Lab supplies and equipment maintenance agreements 6374000 4956000 1418000 0 Allocation of Operations and Maintenance 0 8194000 -8284000 90000 Allocation of Depreciation reported in C 0 5563000 -5601000 38000 1113000 506000 560000 47000 62072000 49262000 12088000 722000 638000 1586000 27667000 23932000 14806000 14784000 81000 57000 889000 908000 97101000 45138000 33415000 51963000 51569000 66831000 30258000 33353000 123000 141000 159446000 193555000 11614000 12579000 0 0 1493000 2694000 519000 16231000 0 0 0 0 9940000 13356000 0 0 3838000 5881000 27404000 50741000 X 75305000 83113000 33472000 35401000 23265000 24300000 132042000 142814000 159446000 193555000 X 5352000 6942000 0 0 0 -1522000 X 0 1 X 1 1 1 X 35346000 41600000 49900000 68019000 47565000 242430000 35346000 41600000 49900000 68019000 47565000 242430000 8004000 234426000 12727000 11019000 14623000 20332000 16849000 75550000 0 0 0 0 0 0 3000 53000 51000 20000 0 127000 318107000 9624000 0.73694 0.76861 X Miscellaneous income RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 1 1 0 1 0 1 0 0 1 181000 1 0 0 181000 0 SchC_P2B_S00_L01 Schedule C, Part II-B, Line 1 The Wistar Institute engaged the services of several lobbying firms whose responsibilities are to provide government relations services to The Wistar Institute at the federal and state level, respectively, with regard to both regulatory and legislative issues. Duties include monitoring and tracking legislation which may be of interest to The Wistar Institute and assisting in finding funding sources for programs. In addition, a number of Wistar staff participate in government affairs advocacy on a fairly regular basis (e.g. visits to Congressional offices to advocate for increases in the NIH budget). We also occasionally ask our board, employees or friends/volunteers to write letters or call their representatives regarding legislation that may impact Wistar. 0 0 X X X 0 12084000 247000 1555000 0 424000 0 13462000 12652000 50000 -214000 0 404000 0 12084000 11357000 73000 1502000 0 280000 0 12652000 8726000 1515000 1386000 0 270000 0 11357000 11374000 64000 -2436000 0 276000 0 8726000 0.1824 0.6518 0.1658 0 0 0 162000 162000 0 37471000 22515000 14956000 0 3539000 2154000 1385000 0 27772000 20469000 7303000 0 28157000 0 28157000 51963000 Isaac J Wistar 1898 fund - BNY Mellon 10870000 F Isaac j Wistar 1893 fund - PNC Bank 1208000 F Isaac J Wistar 1902 Contingent Fund - BNY Mellon 581000 F Effingham B Morris Biological Fund - BNY Mellon 1523000 F Carlos Frederick MacDonald Res fd - BNY Mellon 197000 F Milton J and Francis H Greenman fd - BNY Mellon 659000 F Charles M and Josephine A Shander fd - PNC Bank 348000 F Hedge and absolute return funds 12434000 F Statutory trust 5533000 F 33353000 Accrued pension expense 5881000 5881000 X 75231000 6942000 0 0 804000 7746000 67485000 0 -61000 -61000 67424000 62133000 0 0 0 61000 61000 62072000 0 0 0 62072000 SchD_P03_S00_L01 Schedule D, Part III, Line 1 Collections consist of Family Memorabilia which is not used in the Institute's operations. SchD_P03_S00_L04 Schedule D, Part III, Line 4 The Institute's Collections constitute a history of medical science in Philadelphia and the history of vaccine development. The museum collections are tied to our Deeds of Trusts and have significant historical value as Wistar was established as the first independent nonprofit biomedical research institute in the country. SchD_P05_S00_L04 Schedule D, Part V, Line 4 The Board of Trustees determines the prudent use for the endowment funds for general purposes and to support research and training programs as specified by the various endowment programs. SchD_P10_S00_L02 Schedule D, Part X, Line 2 The Institute is a not-for-profit institution which has been determined by the Internal Revenue Service to be exempt from federal income taxes under Section 501(c)(3) of the Internal Revenue Code (IRC). The Institute accounts for uncertainties in income taxes in accordance with authoritative guidance, which prescribes a recognition threshold of more-likely-than-not to be sustained upon examination by the appropriate taxing authority. Measurement of the tax uncertainty occurs if the recognition threshold has been met. Management determined that there were no tax uncertainties that met the recognition threshold for the years ended December 31, 2012 and 2011. As of May 3, 2013, the Institute's federal Return of Organization Exempt from Income Tax Returns for 2011, 2010, and 2009 remain subject to examination by the IRS. SchD_P11_S00_L02d Schedule D, Part XI, Line 2d Net gain on Beneficial Interests in Trusts SchD_P11_S00_L04b Schedule D, Part XI, Line 4b Fundraising event expenses SchD_P12_S00_L02d Schedule D, Part XII, Line 2d Fundraising event expenses Taxin Golf Tournament 183000 152000 31000 0 9000 39000 0 0 13000 0 0 183000 152000 31000 0 9000 39000 0 0 13000 61000 -30000 X X X X 0 1 X X X X 0 0 0 0 0 0 0 1 0 Russel Kaufman MD 541000 0 78000 0 62000 0 32000 0 11000 0 724000 0 0 0 Dario Altieri 360000 0 52000 0 1000 0 32000 0 14000 0 459000 0 0 0 Larry Keinath 232000 0 34000 0 2000 0 32000 0 11000 0 311000 0 0 0 Elizabeth O'Brien 208000 0 31000 0 27000 0 33000 0 25000 0 324000 0 0 0 Alan Stiles 110000 0 0 0 0 0 10000 0 7000 0 127000 0 0 0 Peter Corrado 171000 0 5000 0 27000 0 24000 0 23000 0 250000 0 0 0 Meenhard Herlyn DVM 238000 0 0 0 3000 0 33000 0 21000 0 295000 0 0 0 David Speicher PhD 237000 0 0 0 1000 0 31000 0 3000 0 272000 0 0 0 Hildegund Ertl MD 228000 0 0 0 1000 0 30000 0 10000 0 269000 0 0 0 Frank Rauscher PhD 213000 0 0 0 1000 0 28000 0 4000 0 246000 0 0 0 Ellen Pure PhD 212000 0 0 0 1000 0 28000 0 12000 0 253000 0 0 0 SchJ_P01_S00_L01a Schedule J, Part I, Line 1a Tax Indemnification and gross-up payments - for tuition benefits; Discretionary spending account - travel and auto allowance for CEO only; Housing allowance for CEO only; Social club dues for CEO only. All amounts included in taxable compensation. SchJ_P01_S00_L01b Schedule J, Part I, Line 1b Tax Indemnification and gross-up payments - yes written policy provided; Discretionary spending account, Housing allowance, and social club dues are provided via employment contract with CEO. SchJ_P01_S00_L07 Schedule J, Part I, Line 7 Non-fixed payments in the form of bonuses. A Philadelphia Authority for Industrial Development 232237287 2011-07-29 55000000 Capital project financing 0 0 0 A 0 0 16231000 0 99000 0 519000 0 0 15613000 0 0 0 0 0 1 A 0 0 0 0 0 0 0 0 0 1 A 0 1 0 0 1 0 0 0 1 A 1 SchK_P02_S00_L03 Schedule K, Part II, Line 3 Proceeds are drawn as construction costs are incurred. Josh Goldblum Family member of Joseph A Goldblum, Trustee 20000 Independent Contractor 0 Citizens Bank of Pennsylvania Officer at Citizens Bank and Wistar Board Member, Dan Fitzpatrick 377000 Banking Services 0 X 23 6359000 Fair Market Value 0 0 1 0 SchM_P01_S00_L09 Schedule M, Part I, Line 9 Based on the number of contributions. F990_P06_S0A_L02 Form 990, Part VI, Section A, Line 2 Daniel Wheeler (Trustee) and Robert Fox (Trustee) are in-Laws. Robert Fox (Trustee) and Richard Horowitz (Trustee) are business associates. F990_P06_S0A_L07a Form 990, Part VI, Section A, Line 7a The University of Pennsylvania and the Wistar family have the right to designate representation to the Board of Trustees. The University of Pennsylvania also approves the Board of Trustees. F990_P06_S0B_L11b Form 990, Part VI, Section B, Line 11b The Audit Committee of the Board of Trustees reviews the 990 prior to filing the return. Also, prior to submission, the Institute posts a copy to the board's website and notifies members of its availability for their information. F990_P06_S0B_L12c Form 990, Part VI, Section B, Line 12c Annually covered persons are required to submit Conflict of Interest Disclosures which are reviewed by management. Covered persons include The Wistar Institute's trustees, officers, "key employees", and next 5 most highly compensated employees. If an individual has any power or influence to approve or disapprove a contract or transaction proposed to be entered into between the Institute and any entity or person having a significant relationship to that individual, that individual has a potential conflict of interest and may not participate in the process leading to the approval, or disapproval of the contract or transaction unless the underlying facts giving rise to the potential conflict of interest are disclosed and approval for participation is obtained. In case of the Board of Trustees, no individual with a potential conflict of interest with respect to a contract or transaction or any other potential conflict of interest may vote to approve or disapprove the contract or transaction. F990_P06_S0B_L15 Form 990, Part VI, Section B, Line 15 The organization uses the following methods to establish compensation of its officers; Compensation committee; independent compensation consultant; Compensation survey or study; and the approval by the Board Compensation committee. The Compensation Committee of the Board of Trustees documents its decisions in the minutes to it's meetings. The Committee obtains an opinion from the independent compensation consultant that the CEO's compensation is reasonable. F990_P06_S0C_L19 Form 990, Part VI, Section C, Line 19 The Institute's governing documents and conflict of Interest policy are available on the Institute's website (www.wistar.org) The Institute's financial statements are available upon request. F990_P11_S00_L09 Form 990, Part XI, Line 9 Loss on disposal of land, buildings and equipment (972,000); Gain on beneficial interest in trusts 804,000; and Pension-net loss (1,354,000). Issac J Wistar Foundation 3601 Spruce Street Philadelphia PA 19104 232593436 Inactive PA 501 (c) (3) PF N/A 0 Tall Cell Technology L P c/o The Connelly Fdn One Tower Bridge Suite 1450 West Conshohocken PA 19428 232811246 Licensing PA N/A Related 157000 2000 0 0 1 0.9 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Tall Cell Technology L P a-iii 157000 Cash payment received representing The Wistar Institute's portion in the partnership's royalties.