2013-08-13T09:52:44-05:00 2012-09-30 990 2011-10-01 042158520 Immune Disease Institute Inc IMMU 6177138000 CLSB 3rd Floor 3 Blackfan Circle Boston MA 02115 Douglas Vanderslice 6173556881 2013-08-09 2011 2016-02-24 21:20:13Z X James Mandell MD 300 Longwood Avenue Boston MA 02115 36276153 0 X www.idi.harvard.edu X 1953 MA Immune Disease Institute, Inc.'s mission is fundamental biomedical research to improve human health, harness inflammation, and strengthen immune defense. X 9 5 244 0 0 0 32291405 30560121 0 0 13332696 277411 5054943 5438621 50679044 36276153 0 0 0 0 13197221 13585479 0 0 18691 25790616 22700977 38987837 36286456 11691207 -10303 21892246 0 8818102 0 13074144 0 Immune Disease Institute, Inc.'s mission is fundamental biomedical research to improve human health, harness inflammation, and strengthen immune defense. 0 0 35370575 0 35853166 Immune Disease Institute, Inc. conducts research on the function and use of components of blood and other tissues. IDI also trains medical and scientific personnel in research. The research projects are funded by private organizations and federal government agencies under grants and contracts that provide for reimbursement of specific expenditures. Annually, IDI publishes over 100 peer reviewed articles in leading journals. 35370575 1 1 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 1 53 0 1 244 1 0 0 0 0 0 0 0 0 0 0 0 X 9 5 0 0 0 0 1 1 1 1 1 0 0 0 1 1 1 1 0 1 1 0 MA X X Douglas Vanderslice - Sr VP of Finance 6173556881 300 Longwood Avenue Boston MA 02115 Carleen Brunelli 1.00 X 0 362496 43562 Robert Carpenter 1.00 X 0 0 0 Gary Fleisher 1.00 X 0 0 0 Harvey Lodish 1.00 X 0 0 0 James Mandell 1.00 X 0 1443499 60386 Walter Pressey 1.00 X 0 0 0 Enid Starr 1.00 X 0 0 0 Frederick Alt 1.00 X X 1471 0 0 David Kirshner 1.00 X X 0 643090 52795 Stuart Novick 1.00 X 0 635237 53286 Rachelle Rosenbaum 1.00 X 90161 0 23462 Steven Simmons 40.00 X 207944 0 33531 Klaus Rajewsky 40.00 X 269809 0 38333 Michael Carroll 40.00 X 248090 0 51524 Denisa Wagner 40.00 X 240319 0 53195 Judy Lieberman 40.00 X 241321 0 49195 Tomas Kirchhausen 40.00 X 213954 0 32401 1513069 3084322 491670 17 0 1 0 Paradigm Construction Co 8 Cook Street Billerica MA 01821 Construction Services 1156730 Wise Construction 21 East Street Winchester MA 01890 Construction Services 996986 Nixon Peabody LLP 100 Summer Street Boston MA 02110 Legal Services 307217 Winter Street Architects 209 Essex Street Salem MA 01970 Architectural Services 194002 Fish & Richardson PC One Marina Park Drive Boston MA 02210 Legal Services 103530 5 2109316 20798070 7652735 30560121 74197 74197 145576 145576 203214 0 203214 203214 203214 CHB/HMS Sublease 531120 3012289 3012289 Contract Revennue 900099 2000000 2000000 Miscellaneous 900099 280756 280756 5293045 36276153 5293045 0 422987 299576 299576 10273721 10139747 119152 14822 717330 706176 10516 638 1570490 1554766 13513 2211 724362 717109 6233 1020 365581 365581 280631 223639 56992 19322 19322 11682466 11672216 10250 366817 366817 82459 50941 31518 1817228 1330301 486927 Supplies 3152432 3135097 17335 Subcontractors 2626802 2626802 Miscellaneous 1047838 903084 144754 Stipends 1030784 1030784 228617 228617 36286456 35370575 897190 18691 932952 0 0 2269831 0 1765399 0 324136 0 0 0 0 752540 0 0 0 3892371 0 6063335 0 3947793 0 0 0 1943889 0 21892246 0 2392567 0 3124837 0 2635305 0 665393 0 0 0 8818102 0 X 11144355 0 269842 0 1659947 0 13074144 0 21892246 0 X -10303 -13063841 X 0 1 1 X 1 1 X 37567240 33014604 45590431 30142165 30560121 176874561 37567240 33014604 45590431 30142165 30560121 176874561 176874561 859316 462357 321812 83501 219773 1946759 1261618 4870850 6947961 20468378 5293045 38841852 217663172 0.81260 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 0 0 0 0 0 0 0 0 1 720 720 0 Explanation of Lobbying Activities: Part II-B, Line 1: Immune Disease Institute, Inc. paid annual membership dues to the Association of Independent Research Institute of $4,800. 15% of the membership dues are applied to lobbying expenses. 1624056 197000 73000 1748056 1643129 0 13993 33066 1624056 1372381 17752 252996 0 1643129 1849439 15000 -350060 141998 1372381 0.05030 0.94970 0.00000 0 1 1 0 Description of Intended Use of Endowment Funds: Part V, Line 4: Part V, line 4: The Uniform Prudent Management of Institutional Funds Act (UPMIFA) permits IDI to appropriate for expenditure or accumulate so much of an endowment fund as IDI determines to be prudent for the uses, benefits, purposes and duration for which the endowment fund is established, thereby eliminating the restriction that a fund could not be spent below its historical dollar value. Seven criteria are to be used to guide IDI in its yearly expenditure decisions: 1) Duration and preservation of the endowment fund; 2) The purposes of IDI and the endowment fund; 3) General economic conditions; 4) Effect of inflation or deflation; 5) The expected total return from income and the appreciation of investments; 6) Other resources of IDI; 7) The investment policy of IDI. Fin 48 (ASC 740) Footnote Part X, Line 2 There is no FIN 48 footnote in the organization's audited financial statements. East Asia and the Pacific 0 0 Program Services Conferences/Education 7522 Europe (Including Iceland & Greenland) 0 0 Program Services Conferences/Education 58994 North America 0 0 Program Services Conferences/Education 18003 0 0 0 0 0 0 84519 0 84519 0 0 0 0 0 0 X X X 0 1 0 0 0 0 0 0 0 Carleen Brunelli 0 278518 0 39150 0 44828 0 22050 0 21512 0 406058 0 9788 James Mandell 0 757427 0 269000 0 417072 0 26950 0 33436 0 1503885 0 67250 David Kirshner 0 489394 0 80000 0 73696 0 24500 0 28295 0 695885 0 20000 Stuart Novick 0 421457 0 86000 0 127780 0 26950 0 26336 0 688523 0 21500 Steven Simmons 207944 0 0 0 0 0 24132 0 9399 0 241475 0 0 0 Klaus Rajewsky 269809 0 0 0 0 0 30625 0 7708 0 308142 0 0 0 Michael Carroll 248090 0 0 0 0 0 30625 0 20899 0 299614 0 0 0 Denisa Wagner 240319 0 0 0 0 0 30502 0 22693 0 293514 0 0 0 Judy Lieberman 241321 0 0 0 0 0 30502 0 18693 0 290516 0 0 0 Tomas Kirchhausen 213954 0 0 0 0 0 24642 0 7759 0 246355 0 0 0 Part I, Line 4b Children's Hospital Corporation, a related organization, made contributions to a supplemental non-qualified retirement plan for the following individuals: Carleen Brunelli $23,100 James Mandell $383,214 David Kirshner $54,708 Stuart Novick $109,080 Supplemental Information Part III Compensation from a Related Organization Part II Compensation provided by a related organization is for executive/employee services to Children's Hospital Corporation; not for trustee or officer service to Immune Disease Institute. Compensation Reported in Prior Form 990 Part II, Column F The compensation reported in Part II, Column B of this Schedule J (Form 990) is for the calendar year 2011 and a portion of it may have already been reported on a prior year Form 990 as deferred compensation. Compensation amounts in Column F reflects the compensation already reported in a prior return and needs to be taken into consideration to correct the overstatement of the cumulative compensation reported as paid to the individuals listed. All assets, Liabilities and Net Assets were merged into Children's Hospital Corporation 2012-09-30 13974732 Book Value 042774441 Children's Hospital Corporation 300 Longwood Avenue Boston MA 02115 501(c)(3) 0 1 0 0 1 1 1 1 0 0 Part I, Line 2e: Frederick Alt, PhD Part I, Line 2e: Upon the merger of Immune Disease Institute (IDI) into Children's Hospital Corporation, IDI will become the Program in Cellular and Molecular Medicine at Children's Hospital. Fred Alt will serve as the program director. Form 990, Part VI, Section A, line 6 On December 24, 2008, the Board of Trustees of IDI and the members of the Board of Trustees of The Children's Medical Center Corporation (CMCC), a Massachusetts nonprofit corporation, entered into a five year affiliation agreement (the agreement) to make IDI CMCC's sixth multidisciplinary research program, the program in cellular and molecular medicine (the program). The effectuation of the affiliation was subject to naming CMCC as the sole corporate member of IDI, adoption by IDI of amended and restated articles of organization, adoption of amended and restated bylaws, and the modification of the IDI Board of Trustees. The date these conditions were satisfied is considered the "closing" date of the affiliation agreement. On February 20, 2009 (the closing date) pursuant to the affiliation agreement, IDI amended its articles of organization and bylaws to name CMC as its sole corporate member. The composition of IDI's Board of Trustees was amended such that CMCC has the authority to appoint the majority of trustees. On March 3, 2010, Immune Disease Institute changed their fiscal year end from June 30 to September 30. Form 990, Part VI, Section A, line 7a Children's Medical Center Corporation has the authority to appoint the majority of trustees of Immune Disease Institute, Inc. Form 990, Part VI, Section A, line 7b On December 24, 2008, the Board of Trustees of IDI and the members of the Board of Trustees of The Children's Medical Center Corporation (CMCC), a Massachusetts nonprofit corporation, entered into a five year affiliation agreement (the agreement) to make IDI CMCC's sixth multidisciplinary research program, the program in cellular and molecular medicine (the program). The effectuation of the affiliation was subject to naming CMCC as the sole corporate member of IDI, adoption by IDI of amended and restated articles of organization, adoption of amended and restated bylaws, and the modification of the IDI Board of Trustees. The date these conditions were satisfied is considered the "closing" date of the affiliation agreement. On February 20, 2009 (the closing date) pursuant to the affiliation agreement, IDI amended its articles of organization and bylaws to name CMC as its sole corporate member. The composition of IDI's Board of Trustees was amended such that CMCC has the authority to appoint the majority of trustees. On March 3, 2010, Immune Disease Institute changed their fiscal year end from June 30 to September 30. Form 990, Part VI, Section B, line 11 The Form 990 was completed by the staff of The Children's Hospital Corporation. The return was reviewed by senior management of the Children's Hospital Corporation. Form 990, Part VI, Section B, line 12c Employees shall conduct business activities in a professional manner consistent with their fiduciary responsibilities to IDI and shall exercise particular care so that no detriment to IDI results from conflicts between their personal financial interests and those of IDI. An employee is considered to have a conflict of interest when the employee, or any of his family or associates: "has an existing or potential financial or other interest which impairs or might appear to impair the employee's independence of judgment in the discharge of his responsibilities to IDI," or "may receive a material, financial or other benefit from knowledge of information confidential to IDI." The "family" of an employee includes his or her spouse, parents, siblings, children and, if living in the same household, other relatives. An "associate' includes any person, trust or organization in which the employee or any member of his or her family "is a director, officer, employee, member, partner, or trustee," or "has a financial interest that enables him or her, acting alone or in conjunction with others, to exercise control or influence policy significantly," or "has any other material association." This policy is to be interpreted and applied in a manner that will best serve the interests of IDI. If an employee or other member of the IDI organization believes that he or she may have a conflict of interest, he or she shall promptly and fully disclose the conflict to the President. This will be documented using the Conflict of Interest Disclosure Form. The employee in question shall refrain from participating in the matter to which the conflict relates until that conflict question has been resolved. In some cases, however, it may be determined that, after full disclosure to those concerned, IDI's interests are best served by the participation of the employee despite the conflict. All employees and trustees are required to complete the conflict of interest disclosure form annually. If a conflict of interest is identified as a result of completing the disclosure or for any other reason, the employee (trustee) and the President will work to resolve the matter including taking whatever action is necessary to preclude the possibility that the identified conflict will impact on an IDI purchasing or business decision. The President will report the conflict to IDI's Board of Trustees. A further aspect of the IDI's conflict of interest policy is intended to assure the proper use of IDI's resources. In the absence of the appropriate written disclosure of conflict of interest and acceptable resolution thereof, no member of the IDI organization shall involve or utilize IDI personnel, resources or vendors in any manner to conduct personal business activities or to use them for personal financial benefit. This does not apply to the occasional use of the telephone or computer to deal with incidental family or personal matters. The routine use of IDI resources to conduct personal business outside of IDI's mission constitutes a breach of the NIH guidelines and is a violation of IDI's conflict of interest policy. The repeated violation of this policy by any individual is a basis for dismissal. IDI investigators at the level of instructor, assistant professor, and full professor are members of the Harvard Faculty of Medicine. As such they are required to file a conflict of interest statement with Harvard Medical School (HMS) on the Ecommons website each year in order to retain their academic appointment and conduct business with the University. Copies of the HMS policy, the form filed, and the statement on research sponsored by industry are available by request. A faculty member is considered to have a conflict of Interest when he/she, any of his/her family, or any associated entity possesses a financial interest in an activity which involves his/her responsibilities as a member of the Faculty of Medicine. Included in these responsibilities are all activities in which the faculty member is engaged in the areas of teaching, research, patient care and administration. The standing committee on conflicts of interest and commitment at HMS is responsible for reviewing the implementation of the policy on a regular basis and providing oversight to assure that the policy s applied consistently to all faculty. Form 990, Part VI, Section B, line 15 All compensation for top management, officers and key employees is approved by the Board of Directors. IDI reviews several independent compensation surveys including the AIRI survey, TSG survey, and the Mass Bio-Counsel survey. All compensation for senior investigators, investigators and junior investigators is developed by comparables within the Longwood Medical Area for basic research scientists and approved by the Board of Directors. Form 990, Part VI, Section C, line 19 Form 990, Part VI, Section C, Line 19: The Form 990, the Audited Financial Statements, and the Organization's governing documents are available upon request. The Audited Financial Statements are posted on the Organization's website. In addition, the Form 990 is available on the website of The Massachusetts Attorney General. Changes in Net Assets or Fund Balances: Form 990, Part XI, line 5: Net unrealized gains on investments: 910,891. Merger with Children's Hospital Corporation -13,974,732. Total to Form 990, Part XI, Line 5: -13,063,841. Children's Hospital Corporation 300 Longwood Avenue Boston MA 02115 042774441 Healthcare MA 501(c)(3) 3 N/A 0 Blood Research Institute CLSB 3rd Floor 3 Blackfan Circle Boston MA 02115 043136318 Lease Prop. MA 501(c)(3) 11C N/A 0 Children's Medical Center Corporation 300 Longwood Avenue Boston MA 02115 041174680 Healthcare MA 501(c)(3) 11B N/A 0 0 0 1 0 0 0 0 0 1 1 0 1 1 1 1 1 1 1