2013-04-29T08:06:17-05:00 2012-06-30 861065772 DELOITTE TAX LLP 100 PEABODY PLACE STE 800 MEMPHIS TN 38103 990 2011-07-01 620646012 ST JUDE CHILDREN'S RESEARCH HOSPITAL INC STJU 9015952261 262 DANNY THOMAS PLACE MEMPHIS TN 381053678 MICHAEL C CANARIOS 9015953301 2013-04-29 1 P00752421 9013226700 2011 2016-03-07 17:11:31Z WILLIAM E EVANS 262 DANNY THOMAS PLACE MEMPHIS TN 381053678 640541108 0 X WWW.STJUDE.ORG X 1959 TN ST. JUDE CHILDREN'S RESEARCH HOSPITAL IS A RESEARCH, TREATMENT AND EDUCATION CENTER. THE MISSION OF ST. JUDE CHILDREN'S RESEARCH HOSPITAL IS TO ADVANCE CURES, AND MEANS OF PREVENTION, FOR PEDIATRIC CATASTROPHIC DISEASES THROUGH RESEARCH AND TREATMENT. CONSISTENT WITH THE VISION OF OUR FOUNDER, DANNY THOMAS, NO CHILD IS DENIED TREATMENT BASED ON RACE, RELIGION OR A FAMILY'S ABILITY TO PAY. 47 42 4134 532 0 0 476590185 537180258 88718150 95536676 -10080 -1847021 8438765 7517144 573737020 638387057 22000 2525909 0 0 321457685 338633780 0 0 0 278552019 293861412 600031704 635021101 -26294684 3365956 2859908493 2930417846 318269139 312661581 2541639354 2617756265 X ST. JUDE CHILDREN'S RESEARCH HOSPITAL IS A RESEARCH, TREATMENT AND EDUCATION CENTER. THE MISSION OF ST. JUDE CHILDREN'S RESEARCH HOSPITAL IS TO ADVANCE CURES, AND MEANS OF PREVENTION, FOR PEDIATRIC CATASTROPHIC DISEASES THROUGH RESEARCH AND TREATMENT. CONSISTENT WITH THE VISION OF OUR FOUNDER, DANNY THOMAS, NO CHILD IS DENIED TREATMENT BASED ON RACE, RELIGION OR A FAMILY'S ABILITY TO PAY. 0 0 309831750 RESEARCH: THE CURRENT BASIC SCIENCE AND CLINICAL RESEARCH AT THE HOSPITAL INCLUDES WORK IN GENE THERAPY, CHEMOTHERAPY, THE BIOCHEMISTRY OF NORMAL AND CANCEROUS CELLS, RADIATION TREATMENT, BLOOD DISEASES, RESISTANCE TO THERAPY, VIRUSES, HEREDITARY DISEASES, INFLUENZA, PEDIATRIC AIDS AND PHYSIOLOGICAL EFFECTS OF CATASTROPHIC ILLNESSSES. THE HOSPITAL AWARDS NO GRANTS TO OUTSIDE AGENCIES. ALL RESEARCH ACTIVITIES ARE CONDUCTED BY HOSPITAL PERSONNEL. 7527349 EDUCATION AND TRAINING: AS PART OF ITS EDUCATIONAL MISSION, THE HOSPITAL PROVIDES APPROXIMATELY 350 POSTDOCTORAL FELLOWSHIPS TO INDIVIDUALS WHO ALREADY HAVE EARNED AN MD, PHD, PHARMD, OR DVM. THE HOSPITAL IS ALSO AFFILIATED WITH THE UNIVERSITY OF TENNESSEE HEALTH SCIENCES CENTER AT MEMPHIS, SERVING AS A TRAINING SITE FOR GRADUATE STUDENTS, MEDICAL STUDENTS, MEDICAL RESIDENTS, AND UNDERGRADUATE STUDENTS IN RELEVANT APPLIED HEALTH PROGRAMS. THIS TRAINING IS PROVIDED IN A VARIETY OF SUBSPECIALTIES AND RESEARCH DISCIPLINES IN THE CLINICAL AND BASIC SCIENCES UNDER THE DIRECTION OF SENIOR CLINICAL AND RESEARCH FACULTY. A PEDIATRIC ONCOLOGY EDUCATION PROGRAM, OFFERING SUMMER TRAINING IN RESEARCH AND CLINICAL DISCIPLINES TO COLLEGE STUDENTS, IS AN INTEGRAL PART OF ST. JUDE'S COMMUNITY EDUCATION ACTIVITIES. ST. JUDE ALSO HAS GRADUATE PROGRAMS CONDUCTED UNDER FORMAL AFFILIATION AGREEMENTS WITH THE UNIVERSITY OF MEMPHIS AND THE UNIVERSITY OF MISSISSIPPI. UNDERGRADUATE PROGRAMS INCLUDE THE RHODES COLLEGE SUMMER PLUS PROGRAM (RHODES COLLEGE) AND CHRISTIAN BROTHERS UNIVERSITY. 289489762 95536676 PATIENT CARE: THE HOSPITAL PROVIDED 16,090 INPATIENT DAYS OF CARE DURING THE YEAR. OUR BONE MARROW TRANSPLANTATION PROGRAM ACCOUNTED FOR 5,016 OR 31% OF THOSE INPATIENT DAYS. PATIENTS MADE 65,964 CLINIC VISITS DURING THE YEAR. 606848861 1 1 0 1 0 0 0 0 0 0 1 0 0 1 1 1 1 1 0 1 1 0 0 0 0 0 1 1 1 0 1 1 0 0 0 0 0 0 0 1 1 1 0 0 0 0 1 1 1 0 0 0 1 733 0 1 4134 1 0 0 0 0 0 0 0 X 47 42 1 0 1 0 0 0 0 1 1 0 1 1 1 1 1 1 1 1 1 1 0 TN X X MICHAEL C CANARIOS 9015952261 262 DANNY THOMAS PLACE MEMPHIS TN 381053678 X JOYCE ABOUSSIE 4.00 X 0 0 0 SUSAN MACK AGUILLARD MD 4.00 X 0 0 0 MAHIR AWDEH MD 4.00 X 0 0 0 JOSEPH S AYOUB JR ESQ 4.00 X 0 0 0 PAUL J AYOUB ESQ 4.00 X 0 0 0 JAMES B BARKATE 4.00 X 0 0 0 MARTHA PERINE BEARD 8.00 X 0 0 0 SHERYL BOURISK 4.00 X 0 0 0 ROBERT A BREIT MD 8.00 X 0 0 0 TERRY BURMAN 8.00 X 0 0 0 STEPHEN J CAMER MD 4.00 X 0 0 0 TONY CHARAF 4.00 X 0 0 0 ANN M DANNER 4.00 X 0 0 0 MICHAEL FRANCIS 4.00 X 0 0 0 FRED P GATTAS JR 4.00 X 0 0 0 FRED P GATTAS III PHARMD 4.00 X 0 0 0 CHRISTOPHER GEORGE MD 4.00 X 0 0 0 JUDY HABIB 4.00 X 0 0 0 GABRIEL GABY HADDAD MD 4.00 X 0 0 0 PAUL K HAJAR 4.00 X 0 0 0 CHUCK HAJJAR 4.00 X 0 0 0 FOUAD HAJJAR MD 4.00 X 0 0 0 FRED R HARRIS 4.00 X 0 0 0 BRUCE B HOPKINS 4.00 X 0 0 0 RICHARD IEYOUB 4.00 X 0 0 0 RICHARD KARAM ESQ 4.00 X 0 0 0 SALLI LEVAN 4.00 X 0 0 0 PAUL MARCUS 4.00 X 0 0 0 MICHAEL D MCCOY 4.00 X 0 0 0 ROBERT T MOLINET 4.00 X 0 0 0 JIM NAIFEH JR 4.00 X 0 0 0 HELEN NUGENT 4.00 X 0 0 0 RAMZI NUWAYHID 4.00 X 0 0 0 THOMAS PENN III 4.00 X 0 0 0 CAMILLE F SARROUF SR ESQ 4.00 X 0 0 0 CAMILLE F SARROUF JR ESQ 4.00 X 0 0 0 JOSEPH G SHAKER 4.00 X 0 0 0 GEORGE A SIMON II 4.00 X 0 0 0 PAUL J SIMON 4.00 X 0 0 0 TERRE THOMAS 4.00 X 0 0 0 TONY THOMAS 4.00 X 0 0 0 RICHARD M UNES 4.00 X 0 0 0 PAUL H WEIN ESQ 4.00 X 0 0 0 TOM WERTZ 4.00 X 0 0 0 RAMZI YOUNIS MD 4.00 X 0 0 0 TAMA ZAYDON 4.00 X 0 0 0 RICHARD C SHADYAC JR 1.00 X 0 593162 41732 WILLIAM E EVANS 55.00 X X 904243 0 35736 JAMES R DOWNING 55.00 X 751130 0 51443 JOSEPH H LAVER 55.00 X 607955 0 80943 RICHARD GILBERTSON 55.00 X 450728 0 59397 MICHAEL B KASTAN 55.00 X 431774 0 42300 MICHAEL CANARIOS 55.00 X 381076 0 78734 GEORGE BIKHAZI 55.00 X 494338 0 46019 ANDREW DAVIDOFF 55.00 X 554719 0 97162 LARRY KUN 55.00 X 654539 0 47851 THOMAS MERCHANT 55.00 X 624902 0 69634 CHING-HON PUI 55.00 X 518464 0 35117 6373868 593162 686068 427 0 1 0 UNIVERSITY OF TENNESSEE 62 S DUNLAP ROOM 300 MEMPHIS TN 38163 MEDICAL 7544857 FLINTCO LLC 2179 HILLSHIRE CIRCLE MEMPHIS TN 38133 GENERAL CONTRACTING 7217359 THE CRUMP FIRM INC 81 MONROE BUILDING MEMPHIS TN 38103 GENERAL CONTRACTING 4453475 CERNER CORP 2800 ROCKCREEK PARKWAY KANSAS CITY MO 64117 CONSULTING 3870433 DYNAMIX GROUP INC PO BOX 116609 ATLANTA GA 303686609 MAINTENANCE SERVICE 2469470 158 441990544 76346395 18843319 537180258 PATIENT CARE 621110 95536676 95536676 95536676 268941 38089 240454 1913597 28487 -1875508 -1847021 -1847021 CAFETERIA/VENDING 722212 2873022 2873022 PATENTS/LICENSING INCO 900099 2551868 2551868 CHGME/CHCA 900099 1267080 1267080 825174 825174 7517144 638387057 101206799 0 0 2525909 2525909 3794976 2371749 1423227 260640463 244431719 16208744 16640894 15606028 1034866 39815353 37339311 2476042 17742094 16638746 1103348 23146610 22024078 1122532 1648180 1568249 79931 174819 166341 8478 31587 31587 55474858 50317396 5157462 657269 625394 31875 2242247 2207185 35062 9860090 9381909 478181 21858290 19724921 2133369 10414587 9912232 502355 1460784 1151316 309468 10034890 10016249 18641 62566580 60102740 2463840 2662524 1822485 840039 LABORATORY SUPPLIES 31733422 31237205 496217 0 PHAMACEUTICAL SUPPLIES 28521912 28075913 445999 0 TELEPHONE 1261843 1130444 131399 0 ALLOCATION ADJUSTMENTS 0 11008242 -11008242 0 30110920 27431513 2679407 635021101 606848861 28172240 0 2426793 630443 10099500 10208625 11133917 8142964 11816086 13199254 3732709 5642230 11203641 9430833 972426144 546492432 423272461 425933712 1494392 1479342 2384728994 2455750443 2859908493 2930417846 75926446 74492116 6415432 5893609 234467223 229186492 1460038 3089364 318269139 312661581 X 1704992562 1782242015 46913705 52799597 789733087 782714653 2541639354 2617756265 2859908493 2930417846 X 3365956 72750955 X 0 1 1 X 1 1 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 0 1 0 0 0 0 1 13750 0 1 17837 31587 0 EXPLANATION OF LOBBYING ACTIVITIES: PART II-B, LINE 1: ST. JUDE RETAINED ALSTON & BIRD FOR FEDERAL POLICY CONSULTING AND SMITH HARRIS & CARR FOR STATE POLICY CONSULTING. AMOUNT LISTED IS RETAINER FEES PRORATED FOR DIRECT FEDERAL AND STATE LEGISLATIVE CONTACTS. 664764341 340263866 324500475 301489069 203465321 98023748 6172734 2763245 3409489 425933712 INTEREST IN THE NET ASSETS OF AMERICAN SYRIAN LEBANESE ASSOCIATED CHARITIES 2454455103 UNAMORTIZED BOND ISSUANCE COSTS 1295340 2455750443 SELF INSURANCE LIABILITY 1975731 WORKMAN'S COMPENSATION 1113633 3089364 638387057 635021101 3365956 -58183 72809138 72750955 76116911 198213838 -58183 -58183 198272021 440115036 440115036 638387057 635021101 0 635021101 0 635021101 DESCRIPTION OF UNCERTAIN TAX POSITIONS UNDER FIN 48: PART X: AS OF JUNE 30, 2012, THE HOSPITAL HAD NOT IDENTIFIED ANY UNCERTAIN TAX POSITIONS UNDER ASC TOPIC 740, INCOME TAXES, REQUIRING ADJUSTMENT TO ITS CONSOLIDATED FINANCIAL STATEMENTS. IN THE EVENT THE HOSPITAL WERE TO RECOGNIZE INTEREST AND PENALTIES RELATED TO UNCERTAIN TAX POSITIONS, IT WOULD BE RECOGNIZED IN THE CONSOLIDATED FINANCIAL STATEMENTS AS INTEREST EXPENSE FOR INTEREST AND MISCELLANEOUS FOR PENALTIES. GENERALLY, TAX YEARS ENDING IN 2009 THROUGH 2012 ARE OPEN TO EXAMINATION BY THE FEDERAL AND STATE TAXING AUTHORITIES, RESPECTIVELY. THERE ARE NO INCOME TAX EXAMINATIONS CURRENTLY IN PROCESS. PART XI, LINE 8 - OTHER ADJUSTMENTS: CHANGE IN INTEREST IN UNRESTRICTED NET ASSETS ALSAC 72,841,983. CHANGE IN INTEREST IN NET ASSETS OF ALSAC -32,845. TOTAL TO SCHEDULE D, PART XI, LINE 8: 72,809,138. PART XII, LINE 4B - OTHER ADJUSTMENTS: NET SUPPORT RECEIVED FROM ALSAC 441,990,544. LOSS FROM DISPOSAL OF PROPERTY AND EQUIPMENT -1,875,508. CENTRAL AMERICA & THE CARIBBEAN 0 0 PROGRAM SERVICES EDUCATION & TRAINING 679182 EAST ASIA AND THE PACIFIC 0 0 PROGRAM SERVICES EDUCATION & TRAINING 369940 MIDDLE EAST AND NORTH AFRICA 0 1 PROGRAM SERVICES EDUCATION & TRAINING 1195362 NORTH AMERICA 0 0 PROGRAM SERVICES EDUCATION & TRAINING 174263 SOUTH AMERICA 0 0 PROGRAM SERVICES EDUCATION & TRAINING 652710 RUSSIA & THE NEWLY INDEPENDENT STATES 0 0 PROGRAM SERVICES EDUCATION & TRAINING 3153 0 1 0 0 0 1 3074610 0 3074610 0 0 0 0 0 0 1 1 0 0 1 1 1 0 0 39467880 245582 39222298 0.06180 102281140 24254418 78026722 0.12290 141749020 24500000 117249020 0.18470 12508353 379 12507974 0.01970 6951650 237842 6713808 0.01060 15223592 15223592 0.02400 280343426 2551868 277791558 0.43740 2917568 2917568 0.00460 317944589 2790089 315154500 0.49630 459693609 27290089 432403520 0.68100 128651 128651 0.00020 13820 13820 0.00000 54288 54288 0.00010 196759 196759 0.00030 0 558000 734088 2064669 -1330581 X 1 1 1 1 ST JUDE CHILDREN'S RESEARCH HOSPITAL

262 DANNY THOMAS PLACE MEMPHIS TN 381053678

X X X SEE SCHEDULE H, PART VI ST JUDE CHILDREN'S RESEARCH HOSPITAL 1 1 0 0 0 1 1 X X X X 1 X 0 1 X 0 0 PART I, LINE 3C: NO FAMILY EVER PAYS ST. JUDE FOR ANYTHING. A BILLING SYSTEM IS MAINTAINED FOR EACH PATIENT SO THAT THE HOSPITAL CAN RECOVER INSURANCE IF IT IS AVAILABLE, BUT ST. JUDE COVERS ALL COSTS NOT REIMBURSED BY INSURANCE, INCLUDING CO-PAYS AND DEDUCTIBLES. WE COVER TOTAL COSTS FOR THOSE WITHOUT INSURANCE. IN ADDITION, ST. JUDE PROVIDES AN UNPARALLELED LEVEL OF SUPPORT SERVICES AT NO COST TO FAMILIES INCLUDING LODGING, TRANSPORTATION AND MEALS. THANKS LARGELY TO DONATIONS FROM THE PUBLIC, WE ARE ABLE TO PROVIDE THESE SERVICES TO ALL PATIENTS, REGARDLESS OF INCOME, SO WE DO NOT NEED TO DETERMINE ELIGIBILITY FOR THIS ASSISTANCE. BY DEFAULT, ALL PATIENTS ARE ELIGIBLE. TO ENSURE FAMILIES ARE TAPPING ALL RESOURCES FOR WHICH THEY ARE ELIGIBLE, WE DO HAVE PROGRAMS TO ASSIST FAMILIES IN ENROLLING IN VARIOUS PUBLIC ASSISTANCE PROGRAMS FOR WHICH THEY MAY QUALIFY, INCLUDING BUT NOT LIMITED TO TENNCARE/MEDICAID, COVER TN, COVER KIDS, CHIPS AND SOCIAL SECURITY. DOING SO ENSURES AN APPROPRIATE SAFETY NET SHOULD THE FAMILY SEEK TREATMENT OUTSIDE OF ST. JUDE AND IT ALLOWS US TO BE GOOD STEWARDS OF DONOR DOLLARS. PART I, LINE 7: COST-TO-CHARGE RATIO DERIVED FROM WORKSHEET 2, RATIO OF PATIENT CARE COST TO CHARGES. COST-TO-CHARGE RATIO USED FOR LINE 7A FINANCIAL ASSISTANCE AT COST AND LINE 7B MEDICAID. PART I, LINE 7G: ST. JUDE CHILDREN'S RESEARCH HOSPITAL INCLUDED AS SUBSIDIZED HEALTH SERVICES SUPPORT FOR SIX AFFILIATE CLINICS TOTALING APPROXIMATELY $5 MILLION. PART I, LINE 7C: CHIPS IS INCLUDED IN MEDICAID IN PART I, LINE 7B BECAUSE IN MANY STATES THE CHIPS PROGRAMS ARE MANAGED BY THE SAME THIRD PARTY ADMINISTRATORS AND IT IS DIFFICULT TO DISTINGUISH BETWEEN CHIPS AND MEDICAID COVERAGE. PART II THE ST. JUDE CHILDREN'S RESEARCH HOSPITAL CEO IS A MEMBER OF MEMPHIS TOMORROW. MEMPHIS TOMORROW IS AN ASSOCIATION OF CHIEF EXECUTIVE OFFICERS OF MEMPHIS' LARGEST ENTERPRISES. THE PURPOSE IS TO BRING TOP BUSINESS LEADERS TOGETHER WITH GOVERNMENT AND CIVIC LEADERS TO FOSTER ECONOMIC PROSPERITY FOR ALL WHO LIVE IN OUR COMMUNITY. ST. JUDE ALSO PARTICIPATES WITH MEMPHIS FAST FORWARD WHOSE STRATEGIES ARE BASED ON THE COMMON SENSE PREMISE THAT ECONOMIC GROWTH AND PROSPERITY, AND IMPROVED QUALITY OF LIFE, WILL FOLLOW ONCE MEMPHIS AND SHELBY COUNTY SUCCESSFULLY ADDRESS THE BASICS: GOOD JOBS, QUALITY EDUCATION, SAFE STREETS AND EFFICIENT GOVERNMENT. THE ST. JUDE CHIEF INFORMATION OFFICER SERVES ON THE BOARD OF THE MEMPHIS COALITION FOR ADVANCED NETWORKING (MCAN) THROUGH THE MEMPHIS RESEARCH CONSORTIUM. MCAN SERVES EDUCATION, RESEARCH, PUBLIC SERVICE, AND ECONOMIC DEVELOPMENT INITIATIVES. MCAN ESTABLISHES VERY HIGH SPEED OPTICAL BROADBAND COMMUNICATION CONNECTIONS WITH OTHER REGIONAL INITIATIVES IN TENNESSEE TO FORM A STATEWIDE HIGH SPEED RESEARCH BACKBONE. FURTHER, MCAN CONNECTS THE MEMPHIS REGION WITH NATIONAL AND INTERNATIONAL RESEARCH AND SCIENTIFIC NETWORKS, ENABLING MEMPHIS AND TENNESSEE A SIGNIFICANT COMPETITIVE ADVANTAGE IN RESEARCH-DRIVEN ECONOMIC DEVELOPMENT. THE ST. JUDE COMPREHENSIVE CANCER CENTER DIRECTOR SERVES ON THE BOARD OF THE MEMPHIS BIOWORKS FOUNDATION. THE MEMPHIS BIOWORKS FOUNDATION IS EXECUTING A STRATEGIC BUSINESS PLAN THAT LEVERAGES THE COMPETITIVE STRENGTHS WITHIN THE REGION WHILE EXPANDING THE INFRASTRUCTURE, EDUCATIONAL OPPORTUNITIES, AND ENTREPRENEUR SUPPORT NEEDED TO EXPAND BIOSCIENCE INDUSTRIES. ST. JUDE IS A MEMBER OF THE ASPIRING FOR PURCHASING EXCELLENCE (APEX) ASSOCIATION OF MEMPHIS. APEX IS AN ASSOCIATION OF PURCHASING AND PROCUREMENT PROFESSIONALS FROM MEMPHIS ORGANIZATIONS WHOSE PURPOSE IS TO PROMOTE BEST PRACTICES IN SUPPLIER DIVERSITY. ADDITIONALLY, ST. JUDE IS SILVER SPONSOR FOR THE MID-SOUTH MINORITY BUSINESS COUNCIL (MMBC) ECONOMIC DEVELOPMENT FAIR. THE MMBC SERVES AS THE MID-SOUTH'S FOREMOST MINORITY BUSINESS DEVELOPMENT ORGANIZATION. THE MMBC HELPS TO DEVELOP A STRONG MINORITY AND WOMEN BUSINESS COMMUNITY IN AN EFFORT TO IMPACT ECONOMICALLY THE ENTIRE MID-SOUTH REGION. THE ST. JUDE OFFICE OF GOVERNMENT AFFAIRS DIRECTOR CO-CHAIRED THE TENNESSEE CANCER COALITION (TCC) WHICH EXISTS TO IDENTIFY AREAS OF GREATEST CANCER BURDEN ON THE CITIZENS OF TENNESSEE. HE CURRENTLY CHAIRS THE ADVOCACY COMMITTEE. THE ST. JUDE COMPREHENSIVE CANCER CENTER DIRECTOR HAS MET WITH STATE LEADERS TO DISCUSS PUBLIC POLICY INITIATIVES DESIGNED TO PROMOTE CANCER CONTROL AND PREVENTION IN TENNESSEE. OTHER ST. JUDE EMPLOYEES ARE ALSO INVOLVED IN THE TCC. ST. JUDE EMPLOYEES PARTICIPATE IN HEALTHY MEMPHIS COMMON TABLE WHICH FOCUSES ITS ENERGIES ON BUILDING COMMUNITY-WIDE COLLABORATION FOR POPULATION HEALTH, HEALTH EQUITY, AND IMPROVING THE HEALTH CARE DELIVERY SYSTEMS OF CARE.THE ST. JUDE CHIEF NURSE OFFICER SERVES ON THE BOARD OF THE NURSING INSTITUTE OF THE MID-SOUTH, A NOT-FOR-PROFIT COLLABORATIVE COMPRISED OF LOCAL HOSPITALS AND SCHOOLS OF NURSING CHALLENGED WITH PROVIDING COMPREHENSIVE HEALTH EDUCATION AND SERVICES TO A WIDELY DIVERSE, POVERTY-RIDDEN COMMUNITY AND WITH ADDRESSING THE HEALTH DISPARITIES FOUND AMONG THESE RESIDENTS. TENNESSEE HAS A SIGNIFICANT PROJECTED NURSING WORKFORCE SHORTAGE; RANKING FIFTH WORST IN 2010.THE PEDIATRIC ONCOLOGY PROGRAM BRINGS FIFTY TO SIXTY STUDENTS EACH SUMMER FOR INTERNSHIPS IN BASIC SCIENCE OR CLINICAL RESEARCH. ADDITIONALLY, EXPERIENTIAL LEARNING INTERNSHIPS ARE STRUCTURED IN MANY AREAS FROM SCIENCE TO ACCOUNTING. THESE PROGRAMS SUPPORT INCREASING THE AWARENESS OF CAREERS IN RESEARCH SCIENCE OR HEALTHCARE AND CONTRIBUTE TO PREPARING STUDENTS TO ENTER THESE CAREERS.CLINICAL EDUCATION AND TRAINING HOSTS THIRTY TO FORTY STUDENTS AS PATIENT CARE OBSERVERS; THESE STUDENTS ARE AT DIFFERENT STAGES OF TRAINING FROM HIGH SCHOOL TO COLLEGE OR MEDICAL SCHOOL AS WELL AS RESIDENTS; THE OBSERVERS ARE DECIDING ON CAREER OPTIONS.THE VOLUNTEER SERVICES DEPARTMENT PROVIDES SUMMER PROGRAMS FOR HIGH SCHOOL AND COLLEGE STUDENTS THAT DRIVE ENTRY INTO HEALTH CAREERS. ST. JUDE EMPLOYEES ARE INVOLVED WITH THE INSTITUTE OF ELECTRICAL AND ELECTRONICS ENGINEERS AND THE MID-SOUTH STEM (SCIENCE, TECHNOLOGY, ENGINEERING, MATHEMATICS) ALLIANCE WHICH HAVE GOALS TO INCREASE THE NUMBER OF STUDENTS WHO CHOOSE SCIENCE AND HEALTH CAREERS AND INCREASE THE QUALITY OF STEM EDUCATION. PART III, LINE 4: BAD DEBT EXPENSE EXPLANATION IN FINANCIAL STATEMENTS FOOTNOTES IS AS FOLLOWS:"NET PATIENT SERVICE REVENUES AND RECEIVABLES - NO FAMILY EVER PAYS THE HOSPITAL FOR THE CARE THEIR CHILD RECEIVES. ACCORDINGLY, NET PATIENT SERVICE REVENUE CONSISTS ONLY OF ESTIMATED NET REALIZABLE AMOUNTS FROM THIRD-PARTY PAYORS FOR SERVICES RENDERED, INCLUDING ESTIMATED RETROACTIVE REVENUE ADJUSTMENTS (IF NECESSARY) DUE TO FUTURE AUDITS, REVIEWS, AND INVESTIGATIONS. RETROACTIVE ADJUSTMENTS ARE CONSIDERED IN THE RECOGNITION OF REVENUE ON AN ESTIMATED BASIS IN THE PERIOD THE RELATED SERVICES ARE RENDERED, AND SUCH AMOUNTS ARE ADJUSTED IN FUTURE PERIODS AS ADJUSTMENTS BECOME KNOWN OR AS YEARS ARE NO LONGER SUBJECT TO SUCH AUDITS, REVIEWS, AND INVESTIGATIONS. PATIENT SERVICE REVENUE HAS BEEN REDUCED BY ADJUSTMENTS FOR UNCOLLECTIBLE ACCOUNTS TOTALING APPROXIMATELY $558,000 AND $532,000 IN 2012 AND 2011 RESPECTIVELY." BAD DEBT EXPENSE IS EQUAL TO CHARGES ON ACCOUNTS DETERMINED TO BE UNCOLLECTIBLE. SEE NARRATIVE FOR PART 1, LINE 3C REGARDING THE ORGANIZATION'S FINANCIAL ASSISTANCE POLICY. ST. JUDE CHILDREN'S RESEARCH HOSPITAL DOES NOT CONSIDER BAD DEBT EXPENSE A COMMUNITY BENEFIT. PART III, LINE 8: ST. JUDE CHILDREN'S RESEARCH HOSPITAL DOES NOT CONSIDER THE MEDICARE SHORTFALL A COMMUNITY BENEFIT. THE SAME COST METHODOLOGY WAS USED FOR FINANCIAL ASSISTANCE, MEANS-TESTED GOVERNMENT PROGRAMS, AND MEDICARE-THE COST TO CHARGE RATIO DERIVED FROM WORKSHEET 2. PART III, LINE 9B: COLLECTION POLICIES ARE THE SAME FOR ALL PATIENTS. ANY LEGAL OBLIGATION OF PAYMENT FOR A PATIENT'S COSTS THAT ARE NOT COVERED BY INSURANCE IS COVERED BY THE GENEROUS ASSISTANCE OF ST. JUDE DONORS WITH THE RESULTS THAT ST. JUDE DOES NOT ASK A PATIENT TO PAY. 'OTHER' COLUMN PART V, SECTION A PHARMACY, ANATOMIC PATHOLOGY LAB, CLINICAL PHARMACOKINETICS LAB, CLINICAL PATHOLOGY LAB PART V, SECTION B, LINE 9: SEE NARRATIVE FOR PART 1, LINE 3C REGARDING THE ORGANIZATION'S FINANCIAL ASSISTANCE POLICY. PART V, SECTION B, LINE 10: SEE NARRATIVE FOR PART 1, LINE 3C REGARDING THE ORGANIZATION'S FINANCIAL ASSISTANCE POLICY. PART V, SECTION B, LINE 15E: SEE NARRATIVE FOR PART 1, LINE 3C REGARDING THE ORGANIZATION'S FINANCIAL ASSISTANCE POLICY. PART V, SECTION B, LINE 19D: SEE NARRATIVE FOR PART 1, LINE 3C REGARDING THE ORGANIZATION'S FINANCIAL ASSISTANCE POLICY. PART VI, LINE 2: IN 1962, INSPIRED TO OPEN A HOSPITAL TO TREAT CHILDREN WITH CATASTROPHIC DISEASES, DANNY THOMAS FOUNDED ST. JUDE CHILDREN'S RESEARCH HOSPITAL. THE HOSPITAL'S MISSION AT THAT TIME WAS TO STUDY AND TREAT DISEASES THAT THREATEN CHILDREN'S LIVES. DANNY THOMAS OPENED ST. JUDE ON THE PREMISE THAT NO CHILD SHOULD DIE IN THE DAWN OF LIFE.CANCERCHILDHOOD CANCERS ARE RARE, ONLY 12,060 NEW CASES ARE EXPECTED TO OCCUR AMONG CHILDREN 14 YEARS OF AGE AND YOUNGER IN 2012; HOWEVER, CANCER IS THE LEADING CAUSE OF DISEASE RELATED DEATH IN U.S. CHILDREN (AMERICAN CANCER SOCIETY. CANCER FACTS & FIGURES 2012. ATLANTA: AMERICAN CANCER SOCIETY; 2012). THE PRINCIPLE FOCUS OF ST. JUDE CHILDREN'S RESEARCH HOSPITAL IS CANCER. SEVENTY-FIVE PERCENT OF ALL RESOURCES AT ST. JUDE ARE INVESTED IN ELUCIDATING BASIC BIOLOGICAL MECHANISMS OF PEDIATRIC CANCERS, AND TRANSLATING THIS KNOWLEDGE INTO IMPROVED DIAGNOSTIC TOOLS AND CURATIVE THERAPIES, WHILE MINIMIZING LONG-TERM SIDE EFFECTS. SEVENTY PERCENT OF OUR CANCER PATIENTS ARE FROM A 10-STATE REGION. THIS INCLUDES THE IMMEDIATE VICINITY STATES OF TN, MS, AR, MO, AL, KY, GA AND STATES WITH ST. JUDE AFFILIATE CLINICS (LA, IL, MO, AL, EASTERN TN). THE DISTRIBUTION OF ST. JUDE CANCER CASES IN RELATION TO RACE, ETHNICITY, AND GENDER IS CONSISTENTLY ALIGNED WITH THE GENERAL DEMOGRAPHICS OF THAT 10-STATE REGION (BASED ON 2010 DATA FROM THE US CENSUS BUREAU) AND WITH THE CANCER SPECIFIC DEMOGRAPHICS (BASED ON SURVEILLANCE EPIDEMIOLOGY AND END RESULTS (SEER) 2009 DATA). FOR EXAMPLE, ESTIMATES FROM THE 2009 SEER DATA SUGGEST THAT WHITES COMPRISE 63%, BLACKS 18.8% AND HISPANICS 15.9% OF THE PEDIATRIC CANCER CASES IN THE 10-STATE REGION. REMARKABLY, 67%, 21%, AND 11%, RESPECTIVELY, OF WHITES, BLACKS AND HISPANICS CONSTITUTE OUR CANCER PATIENT POPULATION (FOR THE PERIOD FROM OCTOBER 1, 2011 TO SEPTEMBER 30, 2012). DEMOGRAPHICS FROM THE ST. JUDE PEDIATRIC CANCER COHORT ARE COMPARED WITH THE DEMOGRAPHICS OF THE 10-STATE REGION ANNUALLY TO MONITOR DEMOGRAPHIC REPRESENTATION OF OUR CANCER PATIENTS IN RELATION TO THE 10-STATE REGION. ALSO MONITORED ANNUALLY IS THE DISTRIBUTION OF SPECIFIC CANCERS IN THE 10-STATE REGION AND COMPARED WITH THE ST. JUDE CANCER POPULATION.OUR RESEARCH AND CLINICAL TRIALS ARE INFORMED BY THE CHILDREN TREATED AT ST. JUDE AND OUR AFFILIATE CLINICS. ST. JUDE OFFERS THERAPEUTIC TRIALS FOR A VARIETY OF CANCERS INCLUDING CENTRAL NERVOUS SYSTEM (CNS) TUMORS, NON-CNS SOLID TUMORS, AND LEUKEMIA/LYMPHOMA. MANY OF THESE TRIALS ARE INSTITUTIONALLY SPONSORED; HOWEVER, ST. JUDE ALSO PARTICIPATES IN A NUMBER OF CLINICAL TRIALS CONSORTIA PROVIDING OUR CANCER PATIENTS ACCESS TO A VARIETY OF THERAPEUTIC STUDIES. PEDIATRIC CANCER PATIENTS MAY EXPERIENCE TREATMENT-RELATED SIDE EFFECTS MANY YEARS AFTER DIAGNOSIS. THE CHILDHOOD CANCER SURVIVOR STUDY AND ST. JUDE LIFE ARE TWO STUDIES, ACTIVE AT ST. JUDE, ASSESSING LATE EFFECTS OF CANCER THERAPY ON PEDIATRIC CANCER SURVIVORS. INFORMATION FROM THESE STUDIES WILL BE USED TO DEFINE RISK GROUPS FOR VARIOUS LATE EFFECTS AND ASSESS INTERVENTIONS.THE RARITY OF PEDIATRIC CANCERS AND OUR UNIQUE POSITION AS A NATIONAL RESOURCE FOR THE RESEARCH AND TREATMENT OF CANCER MEANS THAT OUR REACH IS EXTENSIVE, INCLUDING LOCAL, REGIONAL, NATIONAL, AND INTERNATIONAL LEVELS. MANY OF OUR INITIATIVES ARE DESIGNED TO IMPACT PEDIATRIC CANCER TREATMENT ON A GLOBAL SCALE. THE NATIONAL COMPREHENSIVE CANCER NETWORK (NCCN), A NOT-FOR-PROFIT ALLIANCE OF 21 OF THE WORLD'S LEADING CANCER CENTERS, IS DEDICATED TO IMPROVING THE QUALITY AND EFFECTIVENESS OF CARE PROVIDED TO PATIENTS WITH CANCER (WWW.NCCN.ORG). ST. JUDE, A NCCN MEMBER IN COLLABORATION WITH THE UNIVERSITY OF TENNESSEE CANCER INSTITUTE, PARTICIPATES IN A NUMBER OF THE VARIOUS COMMITTEES AND GUIDELINES PANELS THAT WORK TOWARD THE GOAL OF IMPROVING THE QUALITY AND EFFECTIVENESS OF CARE PROVIDED TO PATIENTS WITH CANCER. THE NCCN GUIDELINES HAVE BECOME THE MOST WIDELY USED GUIDELINES IN ONCOLOGY PRACTICE AND HAVE BEEN REQUESTED BY CANCER CARE PROFESSIONALS IN OVER 115 COUNTRIES.HEMATOLOGY THE GEOGRAPHIC TREATMENT AREA FOR ST. JUDE ENCOMPASSES 21 COUNTIES IN WESTERN TENNESSEE INCLUDING MEMPHIS, AND AREAS IN EAST ARKANSAS AND NORTH MISSISSIPPI. MORE THAN 70,000 PEOPLE IN THE UNITED STATES HAVE SICKLE CELL DISEASE (SCD), AND IT IS ESTIMATED THAT MORE THAN 1 MILLION PEOPLE WORLDWIDE SUFFER FROM THE DISEASE. IT IS THE MOST FREQUENT GENETIC BLOOD DISORDER IN THE WORLD. ST. JUDE HAS ONE OF THE LARGEST PEDIATRIC SCD PROGRAMS IN THE COUNTRY AND PROVIDES COMPREHENSIVE TREATMENT AND EDUCATION TO MORE THAN 800 CHILDREN WITH SCD IN THE GEOGRAPHIC TREATMENT AREA. THE NUMBER OF NEW PATIENTS WITH SCD ACCEPTED TO THE SCD PROGRAM AT ST. JUDE HAS REMAINED STABLE OVER MANY YEARS. SCD IS DIAGNOSED BY STATE-WIDE NEWBORN SCREENING. OUR SCD INFANT TODDLER PROGRAM CONTACTS AND ACCEPTS ALL CHILDREN DIAGNOSED WITH THE DISEASE OR TRAIT TO ITS COMPREHENSIVE CARE SERVICE OR TRAIT COUNSELING SERVICE. ST. JUDE PROVIDES CONFIRMATORY TESTING, EDUCATION AND COMPREHENSIVE CARE AND FOLLOW-UP THROUGHOUT CHILDHOOD. THIS INCLUDES COMMUNITY OUTREACH AND EDUCATION OF THE LOCAL COMMUNITY. ST. JUDE HAS ESTABLISHED A FORMAL TRANSITION PROGRAM TO ADULT CARE FOR PATIENTS WITH SCD AND PROVIDES SUPPORT TO PATIENTS AND FAMILIES THROUGHOUT THE TRANSITION PROCESS. THE TRANSITION PROGRAM STAFF AT ST. JUDE CLOSELY COLLABORATES WITH THE NEWLY OPENED LOCAL, ADULT SCD CENTER AND ALL OTHER COMMUNITY PHYSICIANS.ST. JUDE HAS CONDUCTED CLINICAL AND EXPERIMENTAL LABORATORY RESEARCH ON SCD SINCE IT WAS FOUNDED. ST. JUDE HAS A HISTORY OF DEVELOPING COLLABORATIVE RESEARCH PARTNERSHIPS WITH THE NATIONAL INSTITUTES OF HEALTH AND OTHER INSTITUTIONS THROUGHOUT THE WORLD. SOME OF THESE PARTNERSHIPS HAVE LED TO MAJOR IMPROVEMENTS IN THE TREATMENT OF CHILDREN WITH SCD WHICH HAVE BENEFITED CHILDREN AND ADULTS WITH SCD WORLDWIDE. FOR EXAMPLE, THE PROPHYLACTIC PENICILLIN STUDIES I AND II LED TO SCREENING FOR NEWBORNS WITH SCD AFTER SHOWING THAT GIVING PENICILLIN TO INFANTS HELPED REDUCE THE RISK OF DEATH FROM INFECTION BY 85%. BEFORE THIS STUDY WAS CONDUCTED, LESS THAN 14 STATES SCREENED NEWBORNS FOR SCD. TODAY ALL 50 STATES SCREEN NEWBORNS FOR SCD. ST. JUDE WAS THE FIRST INSTITUTION TO CURE SCD THROUGH BONE MARROW TRANSPLANTATION (BMT) WHICH REMAINS THE ONLY CURE FOR THE DISEASE. AS A RESULT, HUNDREDS OF CHILDREN AROUND THE WORLD HAVE RECEIVED BMT TO CURE SCD; HOWEVER, IT IS NOT A VIABLE CURE FOR EVERYONE WITH SCD. WHILE GREAT STRIDES HAVE BEEN MADE IN INCREASING THE LIFESPAN OF CHILDREN WITH SCD, MORE RESEARCH IS NEEDED TO FIND A VIABLE CURE AND/OR TREATMENTS THAT PREVENT COMPLICATIONS OF THE DISEASE AND IMPROVE THE QUALITY OF LIFE FOR CHILDREN WITH SCD. ST. JUDE ALSO PROVIDES CLINICAL SERVICES FOR APPROXIMATELY 800 CHILDREN PER YEAR WITH OTHER NON-MALIGNANT HEMATOLOGICAL DISORDERS THROUGH A STRONG RELATIONSHIP WITH LOCAL COMMUNITY PHYSICIANS. ALL CHILDREN FROM THE GEOGRAPHIC TREATMENT AREA OF ST. JUDE WITH ILLNESSES SUCH AS HEMOPHILIA, APLASTIC ANEMIA, THROMBOSIS, THALASSEMIA, SPHEROCYTOSIS, AND IMMUNE THROMBOCYTOPENIC PURPURA ARE REFERRED TO AND RECEIVE STATE-OF THE-ART CARE FROM ST. JUDE PHYSICIANS AND MEDICAL STAFF. SPECIFICALLY FOR THE LOCAL POPULATION OF ABOUT 250 CHILDREN SEEN FOR EVALUATION AND CARE OF BLEEDING AND THROMBOSIS DISORDERS, ST. JUDE HAS RECENTLY ESTABLISHED A FEDERALLY ACKNOWLEDGED PEDIATRIC HEMOPHILIA TREATMENT CENTER WHICH NOW PROVIDES STATE-OF-THE-ART COMPREHENSIVE CARE AND ALSO PARTICIPATES IN REGIONAL AND NATIONAL CLINICAL RESEARCH.HIVTHE ADOLESCENT MEDICINE TRIALS NETWORK (ATN)-SPONSORED NATIONAL PROJECT, CONNECT TO PROTECT (C2P), HAS BEEN A MAJOR CONTRIBUTION TO THE STRONG COMMUNITY TIES THAT THE ST. JUDE ADOLESCENT TRIALS UNIT HAS ESTABLISHED AND STRENGTHENED OVER THE PAST SIX YEARS. THE C2P MEMPHIS COALITION DEVELOPS SUSTAINABLE POLICIES, PROGRAMS AND PRACTICES FOR THE SOLE PURPOSE OF REDUCING THE NUMBER OF HIV INFECTED INDIVIDUALS IN VULNERABLE POPULATIONS. THE COALITION INCLUDES 26 AGENCIES REPRESENTING A RICH AND DIVERSE MIX OF INDIVIDUALS FROM VARIOUS SECTORS IN THE MEMPHIS COMMUNITY, INCLUDING FAITH-BASED, SCHOOL, BUSINESS, CIVIC/COMMUNITY, HOSPITAL, YOUNG ADULTS AND HEALTHCARE ORGANIZATIONS. THESE STRATEGIC PARTNERSHIPS HAVE ALLOWED FOR SHARED RESPONSIBILITY IN THE TRANSFORMATION OF OUR COMMUNITIES. THIS IS ESPECIALLY IMPORTANT TO ENSURE OUR EFFORTS ARE DEVELOPED IN A MANNER THAT GUARANTEES SUSTAINABILITY. THE C2P TEAM USED FEDERAL, STATE AND LOCAL RESOURCES TO IDENTIFY AT-RISK YOUTH AND CREATE A PROFILE OF AVAILABLE COMMUNITY RESOURCES. REPRESENTING SEVEN DIFFERENT SECTORS, THIS TEAM COMPARED DISEASE AND RISK RATES WITH SERVICE AVAILABILITY, NEIGHBORHOOD STRENGTHS, AND NEIGHBORHOOD NEEDS TO ZERO IN ON PREVENTION STRATEGIES MOST NEEDED TO PROTECT THE HEALTH OF OUR CITY'S YOUTH. THE C2P MEMPHIS COALITION HAS IDENTIFIED HIGH-RISK ZIP CODES WITHIN THE COMMUNITY AND AREAS OF HIGH PREVALENCE IN SURROUNDING RURAL AREAS. THE IDENTIFIED ROOT CAUSES GATHERED THROUGH MIXED METHODS TOOLS-QUANTITATIVE AND QUALITATIVE-HELPED TO SHAPE A STRATEGIC PLAN AND IDENTIFY OPPORTUNITIES FOR IMPLEMENTATION OF STRUCTURAL AND SYSTEMATIC CHANGES. THROUGH THIS YEAR, THE COALITION HAS SUCCESSFULLY COMPLETED SIX STRUCTURAL CHANGE OBJECTIVES AND MORE THAN 75 COMMUNITY ACTION STEPS TOWARD OUR STRATEGIC PLAN.OTHER COMMUNITY INITIATIVES INCLUDE THE STRATEGIC MULTISITE INITIATIVE FOR THE IDENTIFICATION, LINKAGE AND ENGAGEMENT IN CARE OF YOUTH WITH & UNDIAGNOSED HIV INFECTION (SMILE) AND HISPANIC OUTREACH. OUR SMILE OUTREACH STAFF OFFERS INDIVIDUAL SUPPORT SERVICES TO ENSURE LINKAGE AND FULL ENGAGEMENT IN MEDICAL CARE FOR HIV POSITIVE YOUTH AND YOUNG ADULTS AGES 13-24. TO DATE, WE HAVE INITIATED CONTACT WITH APPROXIMATELY 300 NEWLY INFECTED YOUTH AND YOUNG ADULTS. PARTICIPANTS IN THE SMILE PROJECT RECEIVE: ASSISTANCE WITH LINKAGE AND ENGAGEMENT IN CARE, CASE MANAGEMENT, CRISIS INTERVENTION, AND REFERRALS TO COMMUNITY SERVICES AND RESOURCES. OUR NEWEST INITIATIVE, HISPANIC OUTREACH, FOCUSES ON IDENTIFYING UNDIAGNOSED ASYMPTOMATIC HIV INFECTION IN HISPANIC/LATINO ADOLESCENTS AND YOUNG ADULTS BY USING SOCIAL AND SEXUAL NETWORK-BASED HIV TESTING STRATEGIES FOR REACHING THOSE MOST AT RISK. USE OF THIS APPROACH INCLUDES IDENTIFICATION OF INDIVIDUALS WHO ARE HIV-INFECTED OR INDIVIDUALS WHO ARE AT INCREASED RISK FOR HIV INFECTION WHO ARE THEN ASKED TO IDENTIFY AND REFER OTHERS IN THEIR SOCIAL AND SEXUAL NETWORKS WHO THEY THINK MAY BE AT RISK FOR HIV FOR COUNSELING, TESTING REFERRAL SERVICES. THROUGH COMMUNITY SUPPORT AND BUY-IN FROM APPROXIMATELY 20 PARTNER AGENCIES, WE HAVE SUCCESSFULLY ENGAGED 94 PARTICIPANTS IN OUTREACH PROTOCOLS. PART VI, LINE 3: AS NOTED IN PART I, LINE 3C, NO FAMILY EVER PAYS ST. JUDE FOR ANYTHING. THIS NOT ONLY INCLUDES TREATMENT-RELATED EXPENSES, BUT A LARGE NUMBER OF SUPPORT SERVICES. HOWEVER, WE ALSO HAVE PROGRAMS TO ASSIST FAMILIES IN ENROLLING IN VARIOUS PUBLIC ASSISTANCE PROGRAMS FOR WHICH THEY MAY QUALIFY, INCLUDING BUT NOT LIMITED TO TENNCARE/MEDICAID, COVER TN, COVER KIDS, CHIPS AND SOCIAL SECURITY. DOING SO ENSURES AN APPROPRIATE SAFETY NET SHOULD THE FAMILY SEEK TREATMENT OUTSIDE OF ST. JUDE AND IT ALLOWS US TO BE GOOD STEWARDS OF DONOR DOLLARS. WE UTILIZE AN OUTSIDER CONTRACTOR TO PROVIDE APPLICATION ASSISTANCE. THE HOSPITAL'S FINANCIAL ASSISTANCE POLICY IS POSTED ON WWW.STJUDE.ORG. THE POLICY IS COMMUNICATED IN ENGLISH AND SPANISH. FOR FAMILIES SPEAKING OTHER LANGUAGES, WE UTILIZE ONSITE INTERPRETER SERVICES AND/OR PROFESSIONAL CONTRACTED TRANSLATION SERVICES. PART VI, LINE 4: ST. JUDE CHILDREN'S RESEARCH HOSPITAL HAS BEEN DESCRIBED AS "A HOSPITAL WITHOUT WALLS" BECAUSE THE HOSPITAL'S OUTREACH INCLUDES THE LOCAL MARKET, AFFILIATE INSTITUTIONS, OTHER AREAS OF THE UNITED STATES/U.S. TERRITORIES, AND THE INTERNATIONAL COMMUNITY. THE LOCAL MARKET ENCOMPASSES MEMPHIS, TENNESSEE AND THE SURROUNDING GEOGRAPHIC AREA WITH APPROXIMATELY 25% OF NEW ONCOLOGY PATIENTS RESIDING WITHIN THIS AREA. FY 12 NEW CANCER PATIENTS REFERRAL AREA NUMBER OF PATIENTS % OF TOTALMEMPHIS, TN AND 115 24.84%SURROUNDING AREAAFFILIATE REFERRAL 159 34.34%NATIONAL REFERRAL 176 38.01% (OTHER AREAS OF U.S.)INTERNATIONAL REFERRAL 13 2.81%GRAND TOTAL 463 100.00%THE DOMESTIC AFFILIATE PROGRAM (DAP) EXTENDS THE PROTOCOL-STRUCTURED TREATMENT AND RESEARCH AT ST. JUDE TO CHILDREN BEYOND OUR PHYSICAL WALLS THROUGH CLINICAL, RESEARCH AND ACADEMIC PARTNERSHIPS WITH PEDIATRIC PROGRAMS WITHIN THE UNITED STATES. THE DAP IS A NETWORK OF PEDIATRIC HEMATOLOGY-ONCOLOGY CLINICS, HOSPITALS AND UNIVERSITIES UNITED TO EXTEND THE MISSION OF ST. JUDE. THE PHYSICIANS AND STAFF AT THESE SITES WORK IN COLLABORATION WITH THE STAFF AT ST. JUDE TO DELIVER PROTOCOL RELATED CARE TO PEDIATRIC HEMATOLOGY-ONCOLOGY PATIENTS, SO THAT PATIENTS CAN RECEIVE CARE CLOSER TO HOME. AFFILIATES ARE CURRENTLY LOCATED IN BATON ROUGE, LA, HUNTSVILLE, AL, JOHNSON CITY, TN, PEORIA, IL, SHREVEPORT, LA, AND SPRINGFIELD, MO. THE AFFILIATES' ENROLLMENT OF PATIENTS ON ST. JUDE CLINICAL TRIALS HELPS ST. JUDE FIND CURES FASTER AND SAVE MORE CHILDREN. THE AFFILIATE PERCENTAGES OF TOTAL ENROLLMENTS VARY BY DISEASE AND CANCER INCIDENCE, BUT FOR NINE RECENT STUDIES THE AFFILIATES ENROLLED APPROXIMATELY 15-70% OF ALL PATIENTS. ST. JUDE PROVIDES FINANCIAL SUPPORT FOR CLINICAL OPERATIONS TO ENSURE EXCELLENT QUALITY OF CARE THAT MEETS ST. JUDE PROTOCOL GUIDELINES AND TO PROVIDE PATIENT ASSISTANCE. THE ST. JUDE AFFILIATE PROGRAM AND OTHER STAFF ASSIST THE AFFILIATES IN THE DEVELOPMENT OF NEW PEDIATRIC HEMATOLOGY-ONCOLOGY PROGRAMS; PROVIDE MONITORING AND CONSULTATION TO IMPROVE PATIENT CARE AND CLINICAL PROCESSES FOR THE AFFILIATE CLINIC, CHILDREN'S HOSPITAL; AND PROVIDE NUMEROUS EDUCATIONAL OFFERINGS AND MENTORING FOR AFFILIATE STAFF. IN ADDITION, ST. JUDE HAS MANY PROCESSES TO ENSURE GOOD CONTINUITY OF CARE BETWEEN THE AFFILIATES AND ST. JUDE. THE AFFILIATES' CLINICAL RECORDS FOR SHARED PATIENTS ARE AVAILABLE IN ST. JUDE MEDICAL RECORDS AND EVERY AFFILIATE HAS ACCESS TO ST. JUDE ELECTRONIC MEDICAL RECORDS OF SHARED PATIENTS. THE AFFILIATES ALSO HAVE ACCESS TO ALL ELECTRONIC RESOURCES, E.G., PATIENT EDUCATION MATERIALS, RESEARCH PROTOCOLS, CLINICAL GUIDELINES AND RESOURCES, EVERYTHING ON THE ST. JUDE INTRANET. IN ADDITION TO ASSISTING THE AFFILIATES, ST. JUDE PROVIDES CONSULTATION SERVICES FOR MORE THAN 2000 NATIONAL AND 500 INTERNATIONAL PHYSICIAN REQUESTS. FOR FISCAL YEAR 2012 (JULY 2011 - JUNE 2012) THE PATIENT CONSULTATIONS BY CONTINENT TOTALED 2,617 AS FOLLOWS:CONTINENT NO. OF PATIENT CONSULTATIONSNORTH AMERICA 2,182 CENTRAL AMERICA & THE CARIBBEAN 69 SOUTH AMERICA 74 EUROPE 70 AFRICA 26 ASIA 160 AUSTRALIA 16 UNKNOWN LOCATION 20 TOTAL 2,617THE MISSION OF THE INTERNATIONAL OUTREACH PROGRAM (IOP) AT ST. JUDE IS TO IMPROVE THE SURVIVAL RATE OF CHILDREN WITH CANCER AND OTHER CATASTROPHIC DISEASES WORLDWIDE, THROUGH THE SHARING OF KNOWLEDGE, TECHNOLOGY AND ORGANIZATIONAL SKILLS. THERE ARE AN ESTIMATED 160,000 NEWLY DIAGNOSED CASES OF CHILDHOOD CANCER WORLDWIDE EACH YEAR, AND CANCER IS EMERGING AS A MAJOR CAUSE OF CHILDHOOD DEATH IN ALL DEVELOPING COUNTRIES. CHILDHOOD CANCER IS BOTH BEING IDENTIFIED THROUGH ACCURATE DIAGNOSIS AND REPLACING OTHER CAUSES OF CHILDHOOD MORTALITY (E.G. HIV, MALNUTRITION, INFECTIONS) AS A MAJOR CAUSE OF DEATH IN DEVELOPING COUNTRIES. WHILE OVER THE PAST 30 YEARS IMPROVED THERAPY HAS DRAMATICALLY INCREASED SURVIVAL RATES FOR CHILDREN WITH CANCER, STILL MORE THAN 70% OF THE WORLD'S CHILDREN WITH CANCER DO NOT HAVE ACCESS TO MODERN TREATMENT. ST. JUDE STRIVES TO ADDRESS THE NEEDS OF THOSE CHILDREN IN COUNTRIES THAT LACK SUFFICIENT RESOURCES AND HELP THEM MANAGE THEIR OWN BURDEN OF CASES EFFECTIVELY. WHILE SICK CHILDREN FROM AROUND THE WORLD HAVE TRAVELED TO OUR HOSPITAL IN MEMPHIS, RECEIVING TREATMENT IN THEIR OWN COUNTRIES IS MORE EFFICIENT AND LESS DISRUPTIVE FOR THEM AND THEIR FAMILIES. BECAUSE OF OUR INTERNATIONAL EFFORTS, WE ARE ABLE TO REACH FAR MORE CHILDREN THAN WOULD EVER BE ABLE TO COME TO MEMPHIS. A BASIC HEALTHCARE INFRASTRUCTURE IS NEEDED TO SUPPORT PEDIATRIC ONCOLOGY PROGRAMS, WHICH IN TURN FURTHER IMPROVES THE DEVELOPMENT OF BASIC HEALTHCARE. AT THE LOCAL LEVEL, THE IOP DEVELOPS PARTNERSHIPS WITH MEDICAL INSTITUTIONS AND FUND-RAISING ORGANIZATIONS AND FACILITATES THE INVOLVEMENT OF OTHER AGENCIES AND ORGANIZATIONS TO SUPPORT KEY PROGRAMS AND THE EDUCATION OF LOCAL PERSONNEL. AT THE REGIONAL LEVEL, THE IOP DEVELOPS PROGRAMS THROUGH THE USE OF TECHNOLOGY. THE PRIMARY GOAL IS TO DEVELOP LOCAL AND REGIONAL SELF-SUFFICIENCY. THIS MODEL RESULTS IN SIGNIFICANT OVERALL IMPROVEMENT IN HEALTHCARE FACILITIES, THE LEVEL OF PRACTICE, THE SELF-CONFIDENCE OF HEALTHCARE PROVIDERS, AND LOCAL COMMUNITY INVOLVEMENT. WE EMPHASIZE THE BUILDING OF REGIONAL EXPERTISE AND DIAGNOSTIC CAPABILITIES, WHICH PROVIDE A CRITICAL MASS OF PROFESSIONALS WHO CONTINUALLY LEARN FROM AND ASSIST EACH OTHER. COST EFFICIENCY IS ALSO REALIZED BECAUSE OF SHARED RESOURCES.ST. JUDE HAS PARTNER SITES ALL AROUND THE WORLD; THERE ARE CURRENTLY 20 OFFICIAL PARTNER SITES IN 14 DIFFERENT COUNTRIES AROUND THE WORLD-BRAZIL, CHILE, CHINA, COSTA RICA, ECUADOR, EL SALVADOR, GUATEMALA, HONDURAS, JORDAN, LEBANON, MEXICO, MOROCCO, PHILIPPINES, VENEZUELA. ST. JUDE HELPS PARTNER MEDICAL INSTITUTIONS DEVELOP TAILORED EVIDENCED-BASED PROTOCOLS FOR TREATING CHILDREN WITH CANCER AND OTHER CATASTROPHIC DISEASES. ST. JUDE PHYSICIANS SERVE AS MENTORS TO PHYSICIANS AT OUR PARTNER SITES AND CONSULT ON DIFFICULT CASES. WE TRAIN NURSES IN BEST PRACTICES IN CLINICAL CARE AND WORK WITH PATHOLOGISTS ON TECHNIQUES FOR ACCURATE DIAGNOSIS. WE ALSO PARTNER WITH LOCAL FUNDRAISING FOUNDATIONS THAT SUPPORT THE MEDICAL PROGRAMS. THIS MODEL HAS PROVEN TO BE HIGHLY EFFECTIVE IN PROVIDING POOR CHILDREN IN DEVELOPING COUNTRIES ACCESS TO MODERN TREATMENT AND CARE.BY SHARING KNOWLEDGE AND TECHNOLOGY WITH THE LOCAL GOVERNMENTS, HEALTHCARE PROVIDERS, AND THE PRIVATE SECTOR IN THESE COUNTRIES, ST. JUDE IS IMPROVING DIAGNOSES AND TREATMENTS TO INCREASE THE SURVIVAL RATES OF CHILDREN ALL ACROSS THE GLOBE. SPECIFICALLY BY* DELIVERING BROAD BASED EDUCATION AND TRAINING ONSITE AT ST. JUDE, IN EACH SPECIFIC COUNTRY SITE, AND THROUGH THE ST. JUDE CURE4KIDSTM WEB SITE. * BUILDING CAPACITY WITHIN PARTICULAR COUNTRIES FOR TREATMENT, CARE AND RESEARCH. PART VI, LINE 5: ST. JUDE CHILDREN'S RESEARCH HOSPITAL WAS OPENED IN 1962 BY ENTERTAINER DANNY THOMAS, WITH THE PURPOSE OF "IMPROVING CHILD HEALTH THROUGH RESEARCH IN BIOLOGY AND PEDIATRICS." OUR MISSION IS TO ADVANCE CURES, AND MEANS OF PREVENTION, FOR PEDIATRIC CATASTROPHIC DISEASES THROUGH RESEARCH AND TREATMENT. CONSISTENT WITH THE VISION OF OUR FOUNDER, NO CHILD IS DENIED TREATMENT BASED ON RACE, RELIGION OR A FAMILY'S ABILITY TO PAY. OUR VISION IS TO BE THE WORLD LEADER IN ADVANCING THE TREATMENT AND PREVENTION OF CATASTROPHIC DISEASES IN CHILDREN. THIS VISION IS PURSUED BY PROVIDING OUTSTANDING PATIENT CARE; BY CONDUCTING BASIC, TRANSLATIONAL AND CLINICAL RESEARCH DESIGNED TO ELUCIDATE BIOLOGICAL MECHANISMS, UNDERSTAND DISEASE PATHOGENESIS, IMPROVE DIAGNOSIS, ENHANCE TREATMENT OUTCOME, PREVENT DISEASES AND MINIMIZE ADVERSE CONSEQUENCES OF TREATMENT; AND BY EDUCATING HEALTHCARE AND SCIENTIFIC RESEARCH PROFESSIONALS. THROUGH THESE EFFORTS WE SEEK TO CURE AND ENHANCE THE QUALITY OF LIFE FOR AN INCREASING PROPORTION OF CHILDREN WHO COME TO US FOR TREATMENT, AND BY EXPANDING AND SHARING KNOWLEDGE, TO ADVANCE TREATMENT OF CHILDREN WITH CATASTROPHIC DISEASES WORLD-WIDE, WHILE DEVELOPING STRATEGIES TO PREVENT CATASTROPHIC DISEASES IN CHILDREN.ST. JUDE COMBINES LABORATORY AND CLINICAL RESEARCH TO ADVANCE THE CARE OF CHILDREN WITH CANCER AND OTHER CATASTROPHIC DISEASES. FOCUSING ON PROVIDING OUTSTANDING PATIENT CARE RESULTS IN RESEARCH FINDINGS THAT TRANSLATE INTO IMPROVED PATIENT OUTCOME. ST. JUDE HAS AN ACADEMIC FACULTY ENGAGED IN A BROAD SPECTRUM OF RESEARCH INCLUDING THERAPEUTIC TRIALS, INVESTIGATION OF DISEASE PATHOGENESIS AND DISCOVERY-ORIENTED BASIC RESEARCH.HOSPITAL OPERATIONS ARE OVERSEEN BY A BOARD OF GOVERNORS; THE MAJORITY ARE NEITHER EMPLOYEES NOR CONTRACTORS OF THE ORGANIZATION, NOR FAMILY MEMBERS THEREOF. RESEARCH ACTIVITIES ARE REVIEWED ANNUALLY BY A SCIENTIFIC ADVISORY BOARD COMPOSED OF INTERNATIONALLY PROMINENT PHYSICIANS AND SCIENTISTS.ST. JUDE CONTRIBUTED TO THE BUILDING OF A STATE-OF-THE ART NEUROSURGICAL FACILITY FOR TREATING PEDIATRIC PATIENTS IN THE SURROUNDING VICINITY AND ST. JUDE BRAIN TUMOR PATIENTS. THE FACILITY IS EQUIPPED WITH INTRA-OPERATIVE IMAGING EQUIPMENT (IMRI). WHEN PURCHASED, ONLY TWO NEUROSURGICAL FACILITIES IN THE UNITED STATES PROVIDED PATIENTS THIS LEVEL OF TREATMENT WHICH ALLOWS IMAGING TO TAKE PLACE DURING SURGICAL PROCEDURES. IMRI EQUIPMENT ALLOWS SURGEONS TO MAKE INFORMED DECISIONS DURING THE SURGERY. LIVE WEB CASTS ALLOW OTHERS TO VIEW PROCEDURES. OUR ASSISTANCE WITH THIS FACILITY HELPS ASSURE THAT CHILDREN IN THE AREA HAVE ACCESS TO THE BEST NEUROSURGICAL TREATMENT AVAILABLE.ST. JUDE IN COLLABORATION WITH WASHINGTON UNIVERSITY IN ST. LOUIS HAS EMBARKED ON AN UNPRECEDENTED PROJECT TO SEARCH THE HUMAN GENOME TO DISCOVER MUTATIONS THAT DRIVE CHILDHOOD CANCER. THE TEAMS JOINED FORCES TO DECODE THE GENOMES OF OVER 600 CHILDHOOD CANCER PATIENTS WHO CONTRIBUTED TUMOR SAMPLES. DISCOVERIES FROM THIS PROJECT WILL CONTRIBUTE TO FINDING TREATMENTS THAT WILL BE USED WORLDWIDE IN DEVELOPING NEW DIAGNOSTIC TESTS AND MORE EFFECTIVE DRUGS TO SAVE THE LIVES OF CHILDREN WITH CANCER. THE THREE-YEAR, $65 MILLION PROJECT WILL HELP SCIENTISTS IDENTIFY THE GENETIC MISSTEPS THAT TURN A WHITE BLOOD CELL INTO A CANCER CELL AND BENEFIT FUTURE CANCER DIAGNOSTICS AND THERAPEUTICS. TO SPEED UP PROGRESS IN DEVELOPING TREATMENTS AGAINST CANCER AND OTHER DISEASES, THE ST. JUDE CHILDREN'S RESEARCH HOSPITAL - WASHINGTON UNIVERSITY PEDIATRIC CANCER GENOME PROJECT RELEASED RESEARCH RESULTS OF COMPREHENSIVE HUMAN CANCER GENOME DATA FOR FREE ACCESS BY THE GLOBAL SCIENTIFIC COMMUNITY. THE AMOUNT OF INFORMATION RELEASED MORE THAN DOUBLES THE VOLUME OF HIGH-COVERAGE, WHOLE GENOME DATA CURRENTLY AVAILABLE FROM ALL HUMAN GENOME SOURCES COMBINED. THIS INFORMATION IS VALUABLE NOT JUST TO CANCER RESEARCHERS, BUT ALSO TO SCIENTISTS STUDYING ALMOST ANY DISEASE. HTTP://EXPLORE.PEDIATRICCANCERGENOMEPROJECT.ORG/ THE CYCLOTRON (PARTICLE ACCELERATOR) AT ST. JUDE ENABLES RESEARCHERS TO TRACK THE GROWTH OF CANCER CELLS, PINPOINT THE PRODUCTION OF NEW DNA BY TUMOR CELLS AND STUDY THE HEARTS OF ADULT PATIENTS RETURNING TO ST. JUDE FOR LIFETIME FOLLOW-UP. THE CYCLOTRON HELPS RESEARCHERS BETTER UNDERSTAND CHILDHOOD CANCER BY ENABLING THEM TO PRODUCE NEW, VERY SHORT-ACTING TRACERS.ST. JUDE LEASES THE SERVICES OF CHILDREN'S GMP, LLC (OF WHICH ST. JUDE IS THE SOLE MEMBER). CHILDREN'S GMP, LLC MANAGES AND OPERATES A GOOD MANUFACTURING PRACTICE (GMP) FACILITY WHICH ENGAGES IN THE PRODUCTION OF BIOLOGICS AND DRUGS FOR RESEARCH. THE GMP OFFERS RESOURCES TO STUDY RARE DISEASES OVERLOOKED BY PHARMACEUTICAL COMPANIES BECAUSE THERE IS LITTLE PROFIT IN MANUFACTURING DRUGS FOR LESSER KNOWN DISEASES. THE FACILITY, OPERATING ACCORDING TO APPROVED FDA STANDARDS, ALLOWS DOCTORS TO TAILOR TREATMENTS SPECIFICALLY FOR AN INDIVIDUAL CHILD.THE CELL AND TISSUE IMAGING CENTER INCLUDES ELECTRON MICROSCOPY AND LIGHT MICROSCOPY. THE FACILITY PROVIDES INVESTIGATORS ACCESS TO TRANSMISSION ELECTRON MICROSCOPY, CONFOCAL LASER SCANNING MICROSCOPY, MULTIPHOTON MICROSCOPY, IMAGE ANALYSIS, CELL MICROINJECTION AND LIVE CELL IMAGING. THE FEI TECNAI 20 200KV FEG ELECTRON MICROSCOPE, WHICH CAN MAGNIFY AN OBJECT 700,000 TIMES, IS AT THE HEART OF THIS PROGRAM. THE ELECTRON MICROSCOPE INSTRUMENT IS ONE OF ONLY 200 OF ITS TYPE IN THE WORLD. THIS TECHNOLOGY ALLOWS RESEARCHERS TO GET A CLOSER LOOK AT CANCER TO BETTER UNDERSTAND HOW IT GROWS AND SPREADS AND RESPONDS TO THERAPY. USING THE ELECTRON MICROSCOPE, RESEARCHERS LEARN HOW CANCER CELLS BREAK AWAY FROM THE TUMOR AND SPREAD THROUGHOUT THE BODY.CONSTRUCTION ON A NEW PATIENT CARE AND RESEARCH BUILDING ON THE ST. JUDE CAMPUS IS UNDERWAY. THE FACILITY WILL HOUSE PROTON BEAM RADIATION THERAPY TECHNOLOGY DESIGNED TO DELIVER RADIATION THERAPY FOR TREATING CHILDREN WITH BRAIN TUMORS AND SEVERAL OTHER CHILDHOOD CANCERS. PROTON THERAPY IS FAR LESS DAMAGING TO SURROUNDING HEALTHY TISSUE THAN OTHER CURRENT RADIATION THERAPIES. THIS EQUIPMENT WILL ENABLE ST. JUDE TO PROVIDE THIS THERAPY IN A MORE INTEGRATED MANNER TO OUTPATIENTS AND ALLOW OUR RADIATION ONCOLOGISTS TO LEAD THE DEVELOPMENT OF NEW TREATMENTS WITH PROTONS. CURRENTLY THERE ARE NO OTHER PROTON THERAPY CENTERS IN THE WORLD DEDICATED SOLELY TO THE TREATMENT OF CHILDREN.ST. JUDE ADMINISTRATIVE LEADERS AND PHARMACEUTICAL DEPARTMENT FACULTY MEMBERS HAVE BEEN AT THE FOREFRONT OF BRINGING NATIONAL ATTENTION TO THE PEDIATRIC CANCER DRUG SHORTAGE TOPIC, ACTIVELY ENGAGING REGULATORY AND LEGISLATIVE BODIES TO UNDERSTAND THE IMPACT THESE DRUG SHORTAGES HAVE ON PEDIATRIC CARE AND RESEARCH. PRESENTATIONS OR WRITTEN TESTIMONY HAVE BEEN PROVIDED TO THE FDA CENTER FOR DRUG EVALUATION AND RESEARCH WORKSHOP, TWO SENATE HEARINGS, AND HEALTH SUBCOMMITTEE OF THE HOUSE COMMITTEE ON ENERGY AND COMMERCE. ST. JUDE FOCUSES ON EDUCATING AND TRAINING THE NEXT GENERATION OF DOCTORS, NURSES, RESEARCHERS AND ACADEMIC LEADERS. FROM PROGRAMS FOR HIGH SCHOOL STUDENTS TO THE POST-DOCTORAL LEVEL, THE HOSPITAL PLAYS A MAJOR ROLE IN PREPARING FUTURE LEADERS OF SCIENCE AND MEDICINE. IN ADDITION TO ONSITE EDUCATION, THE INTERNATIONAL OUTREACH PROGRAM PROVIDES AN EDUCATION AND COLLABORATION WEB SITE, CURE4KIDS [TM] (WWW.CURE4KIDS.ORG). THE WEB SITE HAS OVER 33,000 USERS IN 185 COUNTRIES. THE ONLINE CONTENT HAS BEEN ACCESSED MORE THAN 6 MILLION TIMES SINCE ITS INCEPTION IN 2002.IN CONJUNCTION WITH MEMPHIS CITY SCHOOLS, ST. JUDE HOLDS KYSS (KNOW YOUR SICKLE STATUS) TRAINING SESSIONS TO TEACH STUDENTS AND SPORTS MANAGERS TO RECOGNIZE THE ONSET OF SCD SYMPTOMS AND HOW TO RESPOND OR HELP STUDENTS WITH SCD MANAGE THEIR SYMPTOMS. THE SICKLE CELL CENTER'S COMMUNITY FOCUS IS THE ENHANCEMENT OF PUBLIC AWARENESS ABOUT SCD AND OTHER HEMOGLOBINOPATHIES, AS WELL AS, THE AVAILABILITY OF COUNSELING AND TREATMENT SERVICES. ST. JUDE DOES THIS THROUGH ADVOCACY PROGRAMS THAT COORDINATE WITH LOCAL SCHOOL SYSTEMS AND COMMUNITY HEALTHCARE AGENCIES. VIA THE CONNECT2PROTECT PROGRAM, ST. JUDE COLLABORATES WITH CHURCHES, OTHER HEALTHCARE ORGANIZATIONS AND CIVIC GROUPS TO RAISE AWARENESS ABOUT PREVENTING THE SPREAD OF HIV/AIDS. THE PRIMARY TARGET IS THE AFRICAN AMERICAN COMMUNITY ALTHOUGH OTHER ETHNIC GROUPS ARE ALSO SERVED INCLUDING ASIAN, CAUCASIAN, AND HISPANIC.THE CANCER EDUCATION PROGRAM FOR SCHOOL STUDENTS TEACHES HEALTHY EATING AND EXERCISE HABITS AS WELL AS DISCOURAGES SMOKING.THE TOLL-FREE QUITLINE IS AVAILABLE TO ANYONE WHO HAS BEEN TREATED FOR PEDIATRIC CANCER IN ORDER TO ENCOURAGE SURVIVORS TO KICK THE SMOKING HABIT. CALLERS TALK TO COUNSELORS FOR SUPPORT AND TOOLS TO SUSTAIN THEIR EFFORTS.THE FUNDRAISING SOURCE FOR ST. JUDE IS ALSAC WHICH RAISES FUNDS SOLELY FOR THE HOSPITAL. BECAUSE OF THE HOSPITAL'S MISSION, PEOPLE NATIONWIDE CONTRIBUTE VIA TENS OF THOUSANDS OF FUNDRAISING EFFORTS. ALSAC CONTRIBUTED $442 MILLION IN FISCAL YEAR 2012 TO MEET THE OPERATING COST OF ST. JUDE. VOLUNTEERS ENHANCE THE QUALITY OF PATIENT CARE BY PARTNERING WITH CLINICAL STAFF TO PROVIDE THAT ADDITIONAL PERSONAL TOUCH. VOLUNTEERS ALSO HELP ENSURE A SAFE ENVIRONMENT. THEY LEND ASSISTANCE AND PROVIDE COMPASSIONATE CONCERN BY OFFERING A LISTENING EAR TO FAMILIES AT A TIME WHEN THEY NEED IT MOST. THEY ARE VITAL AMBASSADORS BETWEEN THE HOSPITAL AND COMMUNITY. 1 NURSING INSTITUTE OF THE MID-SOUTH INC 920 MADISON AVENUE SUITE 815 MEMPHIS TN 381630000 261325853 501(C)(3) 25000 NURSING WORKFORCE DEVELOPMENT UNIVERSITY OF TENNESSEE HEALTH SCIENCES CENTER 62 S DUNLAP SUITE 103 MEMPHIS TN 381630000 626001636 GOV'T ENTITY 2000000 COLLABORATION AND SUPPORT OSF SAINT FRANCIS MEDICAL CENTER 530 NE GLEN OAK AVENUE PEORIA IL 616370000 370662569 501(C)(3) 490909 OPERATION OF THE ST. JUDE CLINIC AT OSF SIU FOUNDATION SIU SCHOOL OF MEDICINE PO BOX 19678 19678 SPRINGFIELD IL 627949676 376024575 501(C)(3) 10000 GENERAL SUPPORT 4 0 PROCEDURE FOR MONITORING GRANTS IN THE U.S.: PART I, LINE 2: SCHEDULE I, PART I, LINE 2: ST. JUDE CHILDREN'S RESEARCH HOSPITAL IS ACTIVELY INVOLVED WITH THE DONEE. THROUGH THIS ACTIVE INVOLVEMENT, THE ORGANIZATIONS ARE MONITORED TO ENSURE THE SUPPORT IS USED APPROPRIATELY. X X 1 1 X X X X X 0 1 0 0 0 0 0 0 0 RICHARD C SHADYAC JR 0 591920 0 0 0 1242 0 25027 0 16705 0 634894 0 0 WILLIAM E EVANS 782166 0 0 0 122077 0 26950 0 8786 0 939979 0 0 0 JAMES R DOWNING 663322 0 0 0 87808 0 26950 0 24493 0 802573 0 0 0 JOSEPH H LAVER 597397 0 0 0 10558 0 56450 0 24493 0 688898 0 0 0 RICHARD GILBERTSON 332797 0 50683 0 67248 0 36586 0 22811 0 510125 0 0 0 MICHAEL B KASTAN 430028 0 0 0 1746 0 26950 0 15350 0 474074 0 0 0 MICHAEL CANARIOS 356473 0 0 0 24603 0 51786 0 26948 0 459810 0 0 0 GEORGE BIKHAZI 473877 0 12000 0 8461 0 26950 0 19069 0 540357 0 0 0 ANDREW DAVIDOFF 517287 0 0 0 37432 0 72837 0 24325 0 651881 0 0 0 LARRY KUN 636157 0 10000 0 8382 0 26950 0 20901 0 702390 0 0 0 THOMAS MERCHANT 475030 0 10000 0 139872 0 37641 0 31993 0 694536 0 26538 0 CHING-HON PUI 462008 0 12500 0 43956 0 26950 0 8167 0 553581 0 0 0 PART I, LINE 1A PART I, LINE 1A: TRAVEL FOR COMPANIONS: FAMILY MEMBER OF ONE OFFICER AND AN EMPLOYEE OF THE HOSPITAL, TRAVELS ON HOSPITAL BUSINESS AS REQUIRED BY THE POSITION. TRAVEL EXPENSES ARE REIMBURSED UNDER AN ACCOUNTABLE PLAN AND NOT RECORDED AS COMPENSATION. TAX INDEMNICATIONS AND GROSS UP PAYMENTS: FOUR OFFICERS WERE REIMBURSED GROSS UP DEPENDENT TUITION WHICH IS INCLUDED AS COMPENSATION TO THE OFFICERS. PART I, LINE 4B WILLIAM E. EVANS, $117,693.00; JAMES R. DOWNING, $74,340.00; MICHAEL CANARIOS, $24,836.29; RICHARD GILBERTSON, $52,632.29 MICHAEL B. KASTAN, $38,660.00; JOSEPH H. LAVER, $29,500.00; THOMAS MERCHANT, $138,318.65; ANDREW DAVIDOFF, $45,886.50; CHING-HON PUI, $39,599.97 SUPPLEMENTAL INFORMATION PART III PART II: RICHARD C. SHADYAC, JR. SERVES AS A VOTING DIRECTOR OF THE BOARD OF ST. JUDE. MR.SHADYAC IS EMPLOYED AS AN OFFICER OF ALSAC A RELATED ORGANIZATION TO ST.JUDE. THE COMPENSATION SHOWN IN COLUMNS (B), (C), (D) AND (E) WAS PAID TO MR. SHADYAC BY ALSAC FOR HIS DUTIES AS CEO OF ALSAC. THE HEALTH EDUCATIONAL & HOUSING FACILITY BOARD OF THE COUNTY OF SHELBYTN 521283414 821697XJ3 2006-12-21 250725271 $130.7 MILLION FOR CONSTRUCTION OF INTEGRATED PATIENT CARE AND RESEARCH 0 0 0 21538779 252012996 3026125 1658551 2188865 129840961 115298494 2008 0 1 1 1 0 0 0 1 1 0.01400 0.01400 1 0 0 0 0 0 0 X FACILITY; 120 MILLION TO ADVANCE REFUND 1999 SERIES ISSUE. PART II, LINE 3, TOTAL PROCEEDS OF ISSUE INCLUDE INVESTMENT EARNINGS IN THE AMOUNT OF $1,278,726. SUSANNA M DOWNING FAMILY MEMBER OF JAMES R. DOWNING, EVP/SCIENTIFIC DIRECTOR 34996 EMPLOYMENT 0 RACHEL LAVER FAMILY MEMBER OF JOSEPH H. LAVER, EVP/CLINICAL DIRECTOR 19259 EMPLOYMENT 0 MARY V RELLING FAMILY MEMBER OF WILLIAM E. EVANS, DIRECTOR/CEO AND EX-OFFICIO DIRECTOR 382969 EMPLOYMENT 0 SHAKER RECRUITMENT ADVERTISING AND COMMUNICATIONS ENTITY MORE THAN 35% OWNED BY DIRECTORS JOSEPH G. SHAKER & ROBERT A. BREIT 544501 ADVERTISING 0 FORM 990, PART VI, SECTION A, LINE 2 FAMILY RELATIONSHIP AMONG DIRECTORS: JOSEPH S. AYOUB, JR. AND PAUL J. AYOUB; FRED P. GATTAS, III AND FRED P. GATTAS, JR.; CAMILLE F. SARROUF, SR. AND CAMILLE F. SARROUF, JR.; GEORGE A. SIMON II AND PAUL J. SIMON; TERRE THOMAS AND TONY THOMAS; ROBERT A. BREIT AND JOSEPH G. SHAKER BUSINESS RELATIONSHIP AMONG DIRECTORS: ROBERT A. BREIT AND JOSEPH G. SHAKER FORM 990, PART VI, SECTION A, LINE 4 THE ST. JUDE BYLAWS WERE REVIEWED AND REVISED BY THE LEGAL AND COMPLIANCE COMMITTEE AND APPROVED BY THE BOARD. THERE WERE TECHNICAL AND CLARIFICATION EDITS TO EVERY ARTICLE OF THE BYLAWS AND THE FOLLOWING REPRESENTS A SUMMARY OF THE SIGNIFICANT EDITS: 1)ARTICLE II - THE PURPOSE OF THE HOSPITAL: THE PURPOSE OF THE HOSPITAL IS MORE CLEARLY DEFINED TO ENSURE ITS PURPOSE IS MORE INCLUSIVE OF THE MEDICAL CARE, HUMANITARIAN EFFORTS AND RESEARCH OF THE HOSPITAL. 2)ARTICLE IV, SECTION 4 - POWERS AND DUTIES OF THE BOARD: THE BYLAW PROVISION RELATIVE TO APPROVAL OF EXPENDITURES BY THE BOARD WAS AMENDED TO PROVIDE THAT IF MANAGEMENT ANTICIPATES THAT EXPENDITURES OF THE OPERATING OR CAPITAL BUDGETS WILL EXCEED THE BOARD APPROVED FISCAL YEAR BUDGET BY MORE THAN ONE MILLION DOLLARS ($1,000,000), THE CEO SHALL NOTIFY THE BOARD CHAIRPERSON AND RECEIVE PRIOR BOARD APPROVAL. 3)ARTICLE IV SECTION 8 - ACTION BY CONSENT OF BOARD: THIS PROVISION WAS AMENDED TO PROVIDE THAT BOARD ACTION MAY BE TAKEN WITHOUT A MEETING IF ALL VOTING MEMBERS CONSENT IN WRITING AND CERTAIN OTHER PROCEDURAL AND NOTICE REQUIREMENTS ARE MET. 4)ARTICLE IV SECTION 9 - QUORUM REQUIREMENTS: THE BOARD QUORUM REQUIREMENT WAS INCREASED FROM ONE THIRD (1/3) TO ONE HALF (1/2) THE NUMBER OF VOTING, ELECTED MEMBERS OF THE BOARD. 5)ARTICLE IV SECTION 11 - COMPENSATION: THIS SECTION WAS CLARIFIED TO PROVIDE THAT NO BOARD MEMBER SHALL RECEIVE COMPENSATION FOR BOARD SERVICE AND THAT ALL RELATIONSHIPS BETWEEN BOARD MEMBERS AND ST. JUDE SHALL BE SUBJECT TO THE CONFLICTS OF INTEREST POLICY. 6)ARTICLE V, SECTION 6 - HOSPITAL DIRECTOR AND CEO: THE CEO DUTIES WERE CLARIFIED AND IT IS PROVIDED THAT THE CEO IS AN EX OFFICIO, VOTING MEMBER OF THE BOARD AND A NON-VOTING, EX OFFICIO MEMBER OF ALL STANDING COMMITTEES EXCEPT AUDIT, COMPENSATION, CONFLICTS OF INTEREST, LIAISON OR NOMINATING. 7)ARTICLE VI, SECTION 1 - STANDING COMMITTEES: THE NAME OF THE LEGAL & BYLAWS COMMITTEE WAS CHANGED TO THE LEGAL AND COMPLIANCE COMMITTEE, AND THE CONFLICT OF INTEREST AND GOVERNANCE COMMITTEES WERE ADDED TO THE LIST OF STANDING COMMITTEES. 8)ARTICLE VII - EXECUTIVE MANAGEMENT BOARD: THIS SECTION RELATED TO A SUBSET OF THE BOARD, WHICH HAD AUTHORITY TO ACT IN CERTAIN INSTANCES WITHOUT THE APPROVAL OF THE ENTIRE BOARD, AND WAS DELETED IN ITS ENTIRETY. 9)ARTICLE X - MEDICAL STAFF: LANGUAGE HAS BEEN ADDED TO ENSURE COMPLIANCE WITH A JOINT COMMISSION STANDARD WHICH PROHIBITS EITHER THE MEDICAL STAFF OR THE BOARD FROM UNILATERALLY AMENDING THE MEDICAL STAFF BYLAWS. ANY DISAGREEMENTS REGARDING PROPOSED REVISIONS OR AMENDMENTS TO THE MEDICAL STAFF BYLAWS SHOULD BE DISCUSSED AT A JOINT CONFERENCE OF THE MEDICAL STAFF AND THE BOARD. REFERENCES TO THE QUALITY ASSURANCE AND PATIENT CARE COMMITTEE'S REVIEW AND APPROVAL AUTHORITY FOR CLINICAL STAFF APPOINTMENTS AND RE-APPOINTMENTS HAVE BEEN CHANGED TO REFLECT THE COMMITTEE'S ACTUAL FUNCTION, WHICH IS TO REVIEW MEDICAL STAFF APPOINTMENTS AND RE-APPOINTMENTS. THE MEDICAL STAFF CONSISTS OF MEDICAL DOCTORS, DOCTORS OF OSTEOPATHY, DENTISTS AND CLINICAL PSYCHOLOGISTS. THE CLINICAL STAFF CONSISTS OF THE MEDICAL STAFF, AS WELL AS CLINICAL PHARMACISTS, PHYSICIAN ASSISTANTS, NURSE PRACTITIONERS, AND CERTIFIED REGISTERED NURSE ANESTHETISTS. 10)ARTICLE XVI - UNIVERSITY AFFILIATION: THE REQUIREMENT THAT THE HOSPITAL BE AFFILIATED WITH THE UNIVERSITY OF TENNESSEE HEALTH SCIENCES CENTER WAS DELETED. 11)PROVISIONS REQUIRING APPROVAL BY THE BOARD OF THE APPOINTMENT OF CERTAIN MEMBERS OF THE MANAGEMENT TEAM HAVE BEEN DELETED. FORM 990, PART VI, SECTION B, LINE 11 IN FEBRUARY OF EACH YEAR, THE AUDIT COMMITTEE AND OFFICERS OF THE BOARD ARE PROVIDED WITH A DRAFT COPY OF THE FORM 990 AND ALL REQUIRED SCHEDULES. THE AUDIT COMMITTEE MEETS WITH ITS TAX PREPARER TO REVIEW THE DRAFT FORM 990 BEFORE IT IS FILED WITH THE IRS. ADDITIONALLY THE COMPENSATION COMMITTEE OF THE BOARD IS PROVIDED WITH A DRAFT COPY OF THE COMPENSATION SECTIONS OF THE FORM 990 FOR REVIEW BEFORE IT IS FILED WITH THE IRS. EACH VOTING MEMBER OF THE BOARD IS PROVIDED WITH A FINAL COPY OF THE FORM 990 AND ALL REQURIED SCHEDULES BEFORE IT IS FILED WITH THE IRS. FORM 990, PART VI, SECTION B, LINE 12C NEW BOARD MEMBERS ARE GIVEN A COPY OF THE CONFLICTS OF INTEREST POLICY, COMPLETE THE ORGANIZATION'S CONFLICTS OF INTEREST DISCLOSURE FORM AND RECEIVE TRAINING ON CONFLICTS OF INTEREST. THERE IS A CONFLICTS OF INTEREST COMMITTEE OF THE BOARD OF DIRECTORS THAT REVIEWS THE ANNUAL CONFLICTS OF INTEREST DISCLOSURE STATEMENTS THAT ARE COMPLETED BY EACH BOARD MEMBER AND DISCUSSES AND RESOLVES CONFLICTS OF INTEREST WITH APPEAL TO THE FULL BOARD. IN ADDITION TO THE CONFLICTS OF INTEREST COMMITTEE, THE ORGANIZATION HAS A COMPLIANCE OFFICER. AMONG OTHER THINGS, THE COMPLIANCE OFFICER CONDUCTS ANNUAL TRAINING FOR ALL EMPLOYEES ON CONFLICTS OF INTEREST. CERTAIN EMPLOYEES ANNUALLY COMPLETE A CONFLICTS OF INTEREST DISCLOSURE FORM WHICH IS REVIEWED BY THE COMPLIANCE OFFICER. CONFLICTS OF INTEREST OF EMPLOYEES ARE HANDLED BY THE COMPLIANCE OFFICER WITH INVOLVEMENT FROM THE BOARD AS APPROPRIATE. DEPENDING UPON THE FACTS AND CIRCUMSTANCES OF THE CONFLICT, POTENTIAL RESTRICTIONS RANGE FROM PROHIBITING A TRANSACTION TO PROHIBITING SOMEONE FROM PARTICIPATING IN A DELIBERATION OR TRANSACTION TO DISCLOSURE TO THE BOARD OF THE CONFLICT OF INTEREST. FORM 990, PART VI, SECTION B, LINE 15 THE EXECUTIVE COMPENSATION COMMITTEE OF THE BOARD COMMISSIONS BIANNUAL THIRD PARTY SALARY SURVEYS TO DETERMINE COMPENSATION FOR THE FOLLOWING OFFICERS: CHIEF EXECUTIVE OFFICER, CHIEF FINANCIAL OFFICER, SCIENTIFIC DIRECTOR, CANCER CENTER DIRECTOR, CLINICAL DIRECTOR. ALL CHANGES TO SALARY FOR THE OFFICERS ARE APPROVED BY THE BOARD. THE LAST REVIEW WAS COMPLETED IN 2011. FORM 990, PART VI, SECTION C, LINE 19 GOVERNING DOCUMENTS AND THE CONFLICT OF INTEREST POLICY ARE NOT AVAILABLE FOR PUBLIC INSPECTION. FINANCIAL STATEMENTS ARE AVAILABLE UPON REQUEST. AVG HOURS DEVOTED TO RELATED ORG(S) WHEN RELATED COMP IS REPORTED: FORM 990, PART VII: RICHARD C. SHADYAC, JR. SERVES AS A VOTING DIRECTOR ON THE BOARD OF ST. JUDE. MR. SHADYAC IS EMPLOYED AS AN OFFICER OF ALSAC, A RELATED ORGANIZATION TO ST. JUDE. THE COMPENSATION SHOWN IN COLUMN (E) WAS PAID TO MR. SHADYAC BY ALSAC FOR HIS DUTIES AS CEO OF ALSAC. CHANGES IN NET ASSETS OR FUND BALANCES: FORM 990, PART XI, LINE 5: NET UNREALIZED LOSSES ON INVESTMENTS: -58,183. CHANGE IN INTEREST IN UNRESTRICTED NET ASSETS ALSAC 72,841,983. CHANGE IN INTEREST IN NET ASSETS OF ALSAC -32,845. TOTAL TO FORM 990, PART XI, LINE 5: 72,750,955. CHILDREN'S GMP LLC 262 DANNY THOMAS PLACE MEMPHIS TN 381053678 620646012 VACCINE MANUFACTURER TN -2802047 774517 N/A THANKS & GIVING LLC 262 DANNY THOMAS PLACE MEMPHIS TN 381053678 201310435 ROYALTY INCOME FROM RECORD SALES TN 184 10632 N/A THE RIGHT WORDS LLC 262 DANNY THOMAS PLACE MEMPHIS TN 381053678 954878579 ROYALTY INCOME FROM BOOK SALES NY 0 0 N/A AMERICAN LEBANESE SYRIAN ASSOCIATED CHARITIES INC 501 ST JUDE PLACE MEMPHIS TN 38105 351044585 SOLICIT SUPPORT FOR THE OPERATION OF ST. JUDE IL 501(C)(3) SEC 170 (B)(1)(A)(IV N/A 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 1 1 0 0 AMERICAN LEBANESE SYRIAN ASSOCIATED CHARITIES INC C 441990544 CASH VALUE AMERICAN LEBANESE SYRIAN ASSOCIATED CHARITIES INC L 441990544 CASH VALUE AMERICAN LEBANESE SYRIAN ASSOCIATED CHARITIES INC O 898773 CASH VALUE AMERICAN LEBANESE SYRIAN ASSOCIATED CHARITIES INC P 830803 CASH VALUE