2014-02-05T12:13:55-08:00 2013-06-30 STACK & ASSOCIATES CPAS 600 W BROADWAY STE 3150 SAN DIEGO CA 921010908 990 2012-07-01 330903864 Vaccine Research Institute of San Diego VACC 8585813960 3030 Bunker Hill Street San Diego CA 92109 Leah Johnson 2014-02-05 true ROBERT STACK P00380610 6192313150 2012 2015-11-30 17:44:51Z 1511437 false false X www.vrisd.org X CA DEVELOPMENT OF PRODUCTS TO TREAT AND/OR PREVENT VIRAL INFECTIONS & CERTAIN OTHER INFECTIOUS DISEASES. 3 2 20 0 2336479 1475851 0 636 269 22000 35317 2359115 1511437 265496 329206 0 1273145 605120 0 0 764332 506632 2302973 1440958 56142 70479 399200 387454 368090 285865 31110 101589 X OUR MISSION IS SCIENTIFIC RESEARCH FOCUSING ON DEVELOPMENT OF PREVENTATIVE AND THERAPEUTIC TREATMENTS FOR BOTH INFECTIOUS (MALARIA, HEPATITIS B AND C, AND INFLUENZA) AND NON-INFECTIOUS DISEASES (CANCER AND CARDIOVASCULAR DISEASE). false false 488720 OTHER VARIOUS R&D PROGRAMS/CONTRACTS 456628 329116 456628 MALARIA-HYBRID-WHCAG VLPS CARRYING 2 CS-REPEAT B CELL EPITOPES AND 4 CS-NONREPEAT B CELL EPITOPES WERE PRODUCED, PURIFIED AND USED TO IMMUNIZE MICE. ALL CONSTRUCTS ELICITED HIGH LEVES OF ANTI-INSERT ANTIBODIES. THE HYBRID-WHCAG VLPS CARRYING CS-REPEAT B CELL EPITOPES CONFERRED 98.7% PROTECTION AGAINST A 10,000 HYBRID SPOROZOITE CHALLENGE, WHEREAS THE NON-REPEAT B CELL EPITOPES WERE MINIMALLY TO NON-PROTECTIVE. HUM CD4+ / CD8+ T CELL RECOGNITION SITES WERE ALSO INSERTED ONTO HYBRID-WHCAG VLPS (I.E. UTC, TH.3R, CS.T3) AND A VLP CONSTRUCT CONTAINING ALL 3 WELL CHARACTERIZED T CELL DOMAINS PRIMED MURINE CS-SPECIFIC T CELLS AS WELL AS WHCAG-SPECIFIC T CELLS. 243071 243071 SALMONELLA GENES ASSOCIATED WITH COLOIZATION OF SPECIFIC HOSTS. THIS PROJECT HAS GENERATED A RESOURCE OF MUTANTS IN ALMOST EVERY PROTEIN CODING GENE IN THE PATHOGEN SALMONELLA. THIS RESOURCE IS BEING USED IN RESEARCH LABORATORIES WORLDWIDE TO UNDERSTAND HOW THIS ORGANISM INFECTS HUMANS AND DOMESTIC ANIMALS. BEYOND THE SCOPE OF THIS PROJECT, THE RESOURCE IS NOW ALSO BEING USED TO IMPROVE SALMONELLA AS A VECTOR FOR VACCINES AND FOR DELIVERING CANCER THERAPEUTICS. 112708 112708 1301127 true false false false false false false false false false true false false false true false true false false false false false false false false false false true false false false false false false false false true false false false false false false false false false true false false false false true 2 0 false 20 true false false false false false false false false 0 false false false false false false false false false false X 3 2 false false false false false false false true true false false false true true true true true true true false X Leah Johnson 8585813960 3030 Bunker Hill St Suite 203 San Diego CA 92109 TERRY DILLMAN 1.00 0.00 X 0 0 0 RANDY HORTON 1.00 0.00 X 0 0 0 DAVID R MILICH PHD 40.00 0.00 X 61101 0 0 JOHN WELSH PHD 40.00 0.00 X 58845 0 0 119946 0 false false false 0 833291 642560 1475851 0 269 269 0 0 0 0 0 0 0 LICENSE 541900 35317 35317 INTEREST 35317 1511437 35586 329206 329206 0 0 0 119946 107951 11995 0 366894 330205 36689 0 118280 106452 11828 0 0 0 0 0 0 0 0 0 0 0 0 165223 132178 33045 2458 2458 0 0 0 0 9486 9486 13247 2649 10598 EQUIPMENT REPAIR AND MAINTENAN 12322 12322 OTHER DIRECT EXPENSES 54353 54353 SUPPLIES 107016 96314 10702 GRANT AND CONTRACT EXPENSE 122080 122080 20447 4959 15488 1440958 1301127 139831 0 48566 286322 134898 8627 8004 41325 151299 31397 0 0 0 0 14944 3664 117254 105307 8338 11947 0 0 0 0 33151 4172 399200 387454 106275 75060 74827 4805 186988 206000 368090 285865 X 31110 101589 31110 101589 399200 387454 70479 X false true X true true true X 1514979 2925657 3135707 2336479 1475851 11388673 0 0 1514979 2925657 3135707 2336479 1475851 11388673 0 11388673 24003 28542 24833 22636 10586 110600 0 0 11499273 0.99040 0.99040 X 13094 4515 8579 104160 100792 3368 11947 UNEARNED REVENUE 206000 206000 1511437 1511437 1511437 1440958 1440958 1440958 false Virginia CW University Stranger Hall Box 614 Richmond VA 23298 520595110 69953 0 RESEARCH GRANTS JOHN HOPKINS UNIV 615 N WOLFE ST STE E3630 BALTIMORE MD 21205 546001758 259253 0 RESEARCH GRANTS 2 0 MICHAEL MCCLELLAND fmr off general X 100000 4805 false true true 4805 Form 990, Part VI, Line 19 Form 990, Part VI, Line 19: Other Organization Documents Publicly Available THE ORGANIZATIONAL DOCUMENTS OF THE ORGANIZATION WILL BE AVAILABLE (FOR INSPECTION OR COPYING) AT THE ORGANIZATION'S MAIN OFFICE DURING NORMAL BUSINESS HOURS.THE PUBLIC INSPECTION COPY OF THE ORGANIZATION'S FORM 990, FROM THE PREVIOUS THREE YEARS, WILL BE AVAILABLE (FOR INSPECTION OR COPYING) AT THE ORGANIZATION'S MAIN OFFICE DURING NORMAL BUSINESS HOURS.THE AUDITED FINANCIAL STATEMENTS WILL BE AVAILABLE (FOR INSPECTION OR COPYING) AT THE ORGANIZATION'S MAIN OFFICE DURING NORMAL BUSINESS HOURS.WHEN RESPONDING TO A PUBLIC INSPECTION REQUEST FOR ANY ORGANIZATIONAL DOCUMENT OR FORM 990 BY ANYONE, THE ORGANIZATION SHALL FULFILL SUCH REQUEST IN A TIMELY FASHION WITHOUT INQUIRING AS TO THE REASON FOR THE PUBLIC INSPECTION REQUEST. Form 990, Part VI, Line 15b Form 990, Part VI, Line 15b: Compensation Review and Approval Process for Officers and Key Employees SALARIES NOT TO EXCEED NEW HIRE CAP OF $197,700. SALARY INCREASES ARE VOTED ON BY THE BOARD OF DIRECTORS. Form 990, Part VI, Line 15a Form 990, Part VI, Line 15a: Compensation Review & Approval Process - CEO, Top Management SALARIES NOT TO EXCEED NEW HIRE CAP OF $197,700. SALARY INCREASES ARE VOTED ON BY THE BOARD OF DIRECTORS. Form 990, Part VI, Line 12c Form 990, Part VI, Line 12c: Explanation of Monitoring and Enforcement of Conflicts ALL BOARD MEMBERS MUST FILL OUT AN ANNUAL STATEMENT ON ANY POSSIBLE CONFLICT OF INTEREST. Form 990, Part VI, Line 11b Form 990, Part VI, Line 11b: Form 990 Review Process THE CEO REVIEWS THE 990 PRIOR TO FILING. Form 990, Part III, Line 4d Form 990, Part III, Line 4d: Other Program Services Description OTHER PROGRAM SERVICES 4: VLP BIOTECH INC 303 Bunker Hill Street 205 SAN DIEGO CA 92109 200425548 BIOTECHNOLOGY CA NA C CORP false false false false false false false false false false true false false false false false false false false false VLP BIOTECH INC j 10317 license agrmnt