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      <DeferredRevenue>
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        <EOY>141067</EOY>
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        <EOY>575013</EOY>
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      <FollowSFAS117>X</FollowSFAS117>
      <UnrestrictedNetAssets>
        <BOY>5179586</BOY>
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      <TemporarilyRestrictedNetAssets>
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      <TotalNetAssetsFundBalances>
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      <TotalLiabNetAssetsFundBalances>
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        <EOY>7317764</EOY>
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      <ReconcilationRevenueExpenses>-1118868</ReconcilationRevenueExpenses>
      <ReconcilationOtherChanges>0</ReconcilationOtherChanges>
      <MethodOfAccountingAccrual>X</MethodOfAccountingAccrual>
      <AccountantCompileOrReview>0</AccountantCompileOrReview>
      <FSAudited>1</FSAudited>
      <FSAuditedBasis>
        <FinancialStatementSeparate>X</FinancialStatementSeparate>
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      <AuditCommittee>1</AuditCommittee>
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        <CurrentTaxYearMinus3Years>12165768</CurrentTaxYearMinus3Years>
        <CurrentTaxYearMinus2Years>1528919</CurrentTaxYearMinus2Years>
        <CurrentTaxYearMinus1Year>1761904</CurrentTaxYearMinus1Year>
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        <Total>26998019</Total>
      </GiftsGrantsContribReceived170>
      <Total170>
        <CurrentTaxYearMinus4Years>7112757</CurrentTaxYearMinus4Years>
        <CurrentTaxYearMinus3Years>12165768</CurrentTaxYearMinus3Years>
        <CurrentTaxYearMinus2Years>1528919</CurrentTaxYearMinus2Years>
        <CurrentTaxYearMinus1Year>1761904</CurrentTaxYearMinus1Year>
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        <Total>26998019</Total>
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      <AmountsSubstContributorsTotal>15411120</AmountsSubstContributorsTotal>
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        <CurrentTaxYearMinus1Year>7382</CurrentTaxYearMinus1Year>
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        <Total>85794</Total>
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        <CurrentTaxYearMinus2Years>23960</CurrentTaxYearMinus2Years>
        <CurrentTaxYearMinus1Year>67204</CurrentTaxYearMinus1Year>
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        <Total>277199</Total>
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      <TotalSupport>27361012</TotalSupport>
      <PublicSupportPertcentage170>0.42350</PublicSupportPertcentage170>
      <PublicSupportPertcentPriorYear>0.42320</PublicSupportPertcentPriorYear>
      <ThirtyThreePercntTestsCY170>X</ThirtyThreePercntTestsCY170>
      <GeneralExplanation>SCHEDULE A, PART IV, LIST OF UNUSUAL GRANTS: BEQUEST DATE: 01/11/13 AMOUNT: 1999996.</GeneralExplanation>
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          <State>RESTRICTED</State>
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        <BookValue>24693</BookValue>
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      <TotalOfBookValueLandBuildings>63807</TotalOfBookValueLandBuildings>
      <FootnoteInPartXIII>X</FootnoteInPartXIII>
      <TotRevenueEtcAuditedFinclStmt>4617385</TotRevenueEtcAuditedFinclStmt>
      <DonatedSrvcAndUseOfFacilities>181328</DonatedSrvcAndUseOfFacilities>
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      <RevenueSubtotal>4436057</RevenueSubtotal>
      <OtherRevenuesNotIncluded>-56500</OtherRevenuesNotIncluded>
      <RevenueNotRptdOnFinStmt>-56500</RevenueNotRptdOnFinStmt>
      <TotalRevenuePerForm990>4379557</TotalRevenuePerForm990>
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      <DonatedServicesUseOfFacilities>181328</DonatedServicesUseOfFacilities>
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      <ExpensesNotRptdF990>237828</ExpensesNotRptdF990>
      <ExpensesSubtotal>5498425</ExpensesSubtotal>
      <ExpensesNotRptdOnFinStmt>0</ExpensesNotRptdOnFinStmt>
      <TotalExpensesPerForm990>5498425</TotalExpensesPerForm990>
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        <Identifier>DESCRIPTION OF UNCERTAIN TAX POSITIONS UNDER FIN 48:</Identifier>
        <ReturnReference>PART X, LINE 2:</ReturnReference>
        <Explanation>THE FOUNDATION IS EXEMPT FROM FEDERAL INCOME AND CALIFORNIA FRANCHISE TAXES UNDER SECTION 501(C)(3) OF THE INTERNAL REVENUE CODE AND SECTION 23701(D) OF THE CALIFORNIA REVENUE AND TAXATION CODE, RESPECTIVELY. ADDITIONALLY, THE FOUNDATION HAS BEEN DETERMINED BY THE INTERNAL REVENUE SERVICE NOT TO BE A PRIVATE FOUNDATION WITHIN THE MEANING OF SECTION 509(A) OF THE INTERNAL REVENUE CODE. THE FOUNDATION FOLLOWS FINANCIAL ACCOUNTING STANDARDS BOARD'S ACCOUNTING STANDARDS CODIFICATION TOPIC 740 INCOME TAXES TO ACCOUNT FOR UNCERTAIN TAX POSITIONS. MANAGEMENT HAS CONCLUDED THAT THE FOUNDATION HAS TAKEN NO UNCERTAIN TAX POSITIONS THAT WOULD REQUIRE ADJUSTMENT TO THE FINANCIAL STATEMENTS TO COMPLY WITH PROVISIONS OF THIS GUIDANCE. THE FOUNDATION IS GENERALLY NO LONGER SUBJECT TO INCOME TAX EXAMINATIONS BY FEDERAL AND STATE TAX AUTHORITIES FOR YEARS PRIOR TO 2009 AND 2008, RESPECTIVELY.</Explanation>
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      <TotalNumberOfOffices>0</TotalNumberOfOffices>
      <TotalNumberOfEmployees>0</TotalNumberOfEmployees>
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      <ContAmountSpent>0</ContAmountSpent>
      <TotalAmountSpent>60000</TotalAmountSpent>
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      <RecipientTable>
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        <ReturnReference>PART I, LINE 2:</ReturnReference>
        <Explanation>SCHEDULE I, PART I, LINE 2: THE VP OF DRUG DISCOVERY CAREFULLY REVIEWS EACH AWARD AND RESEARCH CONTRACT TO ENSURE COMPLIANCE WITH ALL FINANCIAL AND PROGRAMMATIC PROVISIONS.</Explanation>
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        <NoncashContribsRptdF990>1987510</NoncashContribsRptdF990>
        <MethodOfDeterminingRevenues>FAIR MARKET VALUE</MethodOfDeterminingRevenues>
      </SecuritiesPubliclyTraded>
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        <Explanation>THE NUMBER OF CONTRIBUTIONS REFLECTS THE NUMBER OF DONORS, NOT THE NUMBER OF ITEMS DONATED.</Explanation>
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      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION B, LINE 11</ReturnReference>
        <Explanation>THE TAXPAYER'S ACCOUNTING FIRM FORWARDED THE FORM 990 TO THE CFO WHO THEN FORWARDED THE FORM 990 TO THE BOARD MEMBERS FOR THEIR REVIEW PRIOR TO FILING THE FORM 990. BOARD MEMBERS WERE ENCOURAGED TO REVIEW THE FORM AND TO FORWARD THEIR QUESTIONS, IF ANY, TO THE CFO.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION B, LINE 15</ReturnReference>
        <Explanation>THE COMPENSATION COMMITTEE, WHICH IS COMPOSED OF THREE OF THE INDEPENDENT DIRECTORS, MUST REVIEW AND APPROVE ALL MANAGEMENT COMPENSATION.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <ReturnReference>FORM 990, PART VI, SECTION C, LINE 19</ReturnReference>
        <Explanation>FINANCIAL STATEMENTS ARE LINKED TO THE WEBSITE. CONFLICT OF INTEREST POLICY AND GOVERNING DOCUMENTS ARE AVAILABLE UPON REQUEST.</Explanation>
      </GeneralExplanation>
    </IRS990ScheduleO>
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