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      <Desc>PVS WORKS TO PREVENT DEATHS FROM PNEUMONIA, INFLUENZA, RESPIRATORY SYNCYTIAL VIRUS, POLIO, AND DIARRHEA AMONG CHILDREN AROUND THE WORLD. WE ACCELERATE THE DEVELOPMENT OF SAFE, EFFICACIOUS, AND AFFORDABLE VACCINES IN PARTNERSHIP WITH PUBLIC AND PRIVATE GROUPS. IN 2013 PVS MADE ADDITIONAL PROGRESS IN ADVANCING RESEARCH AND DEVELOPMENT OF A NUMBER OF PROMISING PNEUMOCOCCAL VACCINE CANDIDATES AND RELATED TECHNOLOGIES. WE ANALYZED THE RESULTS OF A PHASE 1 TRIAL OF A PNEUMOCOCCAL WHOLE CELL VACCINE WE ARE DEVELOPING IN PARTNERSHIP WITH BOSTON CHILDREN'S HOSPITAL AND PREPARED FOR A PHASE 1 AND 2 STUDY IN ADULTS AND TODDLERS IN KENYA. WE ALSO ADVANCED A PNEUMOCOCCAL CONJUGATE VACCINE CONTAINING TEN SEROTYPES (PCV-10) IN PARTNERSHIP WITH THE SERUM INSTITUTE OF INDIA. TAILORED TO CHILDREN'S NEEDS IN LOW-RESOURCE COUNTRIES, THE PCV-10 CANDIDATE IS DESIGNED TO BE AFFORDABLE AND FOCUSES ON VARIETIES OF THE PNEUMOCOCCUS BACTERIUM THAT ARE PREVALENT IN THESE COUNTRIES. INFECTION WITH ROTAVIRUS IS A MAJOR CAUSE OF SEVERE DIARRHEA AND DEATH AMONG YOUNG CHILDREN IN LOW-RESOURCE COUNTRIES. PVS ACCELERATES THE INTRODUCTION OF SAFE, AFFORDABLE, AND EFFECTIVE ROTAVIRUS VACCINES BY PROVIDING TECHNICAL AND FINANCIAL SUPPORT TO EMERGING-COUNTRY MANUFACTURERS. IN PARTNERSHIP WITH BHARAT BIOTECH OF INDIA, WE CONDUCTED A PHASE 3 TRIAL TO DETERMINE THE EFFICACY OF ONE OF THESE VACCINES. WE ACCUMULATED SUFFICIENT CASES TO HAVE THE DATA REVIEWED BY THE STUDY'S DATA AND SAFETY MONITORING BOARD. THE VACCINE WAS SHOWN TO SIGNIFICANTLY REDUCE SEVERE ROTOVIRUS DIARRHEA BY MORE THAN HALF (56 PERCENT DURING THE FIRST YEAR OF LIFE) WITH PROTECTION CONTINUING INTO THE SECOND YEAR OF LIFE. THE VACCINE EFFICACY COMPARES FAVORABLY WITH THAT OF THE CURRENTLY LICENSED VACCINES BUT WILL BE FAR MORE AFFORDABLE. WE SUBMITTED A LICENSE APPLICATION TO THE DRUG CONTROLLER GENERAL OF INDIA AND RECEIVED A FAVORABLE RECOMMENDATION IN AUGUST 2013 FROM INDIA'S NEW DRUG ADVISORY COMMITTEE. WE ALSO SUPPORTED THE GOVERNMENT TO HOST A SCIENTIFIC CONFERENCE TO PRESENT THE RESULTS. SUBSEQUENTLY, WE COMPLETED THE PHASE 3 STUDY AND FINAL DATA SET, WHICH SHOWED ROBUST EFFICACY OF THE VACCINE IN THE SECOND YEAR OF LIFE.IN ADDITION, IN 2013 PVS COMPLETED A PHASE 1 STUDY OF A NOVEL, NON-REPLICATING ROTAVIRUS VACCINE. BECAUSE THE RESULTS WERE ENCOURAGING, WE BEGAN PREPARATIONS FOR A PHASE 2 TRIAL IN SOUTH AFRICA. PVS ALSO PARTNERS WITH PUBLIC- AND PRIVATE-SECTOR ORGANIZATIONS TO ADVANCE THE RESEARCH AND DEVELOPMENT OF VACCINES AGAINST THE TWO LEADING BACTERIAL CAUSES OF DIARRHEA, SHIGELLA AND ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC). KEY ACTIVITIES IN 2013 INCLUDED COMPLETING A PHASE 1 TRIAL OF THE INACTIVATED TRIVALENT WHOLE CELL SHIGELLA VACCINE; INITIATING A PHASE 1 STUDY OF A LIVE, ATTENUATED SHIGELLA SONNEI VACCINE CANDIDATE; COMPLETING A PHASE 1 TRIAL OF A LIVE, ATTENUATED ETEC VACCINE; CONDUCTING A PHASE 1 TRIAL OF THAT SAME VACCINE WITH A NOVEL ADJUVANT (AN INGREDIENT THAT BOOSTS THE BODY'S IMMUNE RESPONSE); AND CONVENING A WORKSHOP OF LEADING SCIENTIFIC EXPERTS TO ASSESS OPTIONS FOR A COMBINED SHIGELLA/ETEC VACCINE.</Desc>
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        <CashGrantAmt>124406</CashGrantAmt>
        <MannerOfCashDisbursementTxt>CHECK/WIRE</MannerOfCashDisbursementTxt>
      </GrantsToOrgOutsideUSGrp>
      <GrantsToOrgOutsideUSGrp>
        <RegionTxt>SOUTH ASIA</RegionTxt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
        <CashGrantAmt>174911</CashGrantAmt>
        <MannerOfCashDisbursementTxt>CHECK/WIRE</MannerOfCashDisbursementTxt>
      </GrantsToOrgOutsideUSGrp>
      <GrantsToOrgOutsideUSGrp>
        <RegionTxt>SOUTH ASIA</RegionTxt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
        <CashGrantAmt>200000</CashGrantAmt>
        <MannerOfCashDisbursementTxt>CHECK/WIRE</MannerOfCashDisbursementTxt>
      </GrantsToOrgOutsideUSGrp>
      <GrantsToOrgOutsideUSGrp>
        <RegionTxt>SOUTH ASIA</RegionTxt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
        <CashGrantAmt>271688</CashGrantAmt>
        <MannerOfCashDisbursementTxt>CHECK/WIRE</MannerOfCashDisbursementTxt>
      </GrantsToOrgOutsideUSGrp>
      <GrantsToOrgOutsideUSGrp>
        <RegionTxt>SOUTH ASIA</RegionTxt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
        <CashGrantAmt>298054</CashGrantAmt>
        <MannerOfCashDisbursementTxt>CHECK/WIRE</MannerOfCashDisbursementTxt>
      </GrantsToOrgOutsideUSGrp>
      <GrantsToOrgOutsideUSGrp>
        <RegionTxt>SOUTH ASIA</RegionTxt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
        <CashGrantAmt>375690</CashGrantAmt>
        <MannerOfCashDisbursementTxt>CHECK/WIRE</MannerOfCashDisbursementTxt>
      </GrantsToOrgOutsideUSGrp>
      <GrantsToOrgOutsideUSGrp>
        <RegionTxt>SOUTH ASIA</RegionTxt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
        <CashGrantAmt>523035</CashGrantAmt>
        <MannerOfCashDisbursementTxt>CHECK/WIRE</MannerOfCashDisbursementTxt>
      </GrantsToOrgOutsideUSGrp>
      <GrantsToOrgOutsideUSGrp>
        <RegionTxt>SUB SAHARAN AFRICA</RegionTxt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
        <CashGrantAmt>935845</CashGrantAmt>
        <MannerOfCashDisbursementTxt>CHECK/WIRE</MannerOfCashDisbursementTxt>
      </GrantsToOrgOutsideUSGrp>
      <GrantsToOrgOutsideUSGrp>
        <RegionTxt>EAST ASIA AND PACIFIC</RegionTxt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
        <CashGrantAmt>-98165</CashGrantAmt>
        <MannerOfCashDisbursementTxt>CHECK/WIRE</MannerOfCashDisbursementTxt>
      </GrantsToOrgOutsideUSGrp>
      <Total501c3OrgCnt>13</Total501c3OrgCnt>
      <TotalOtherOrgCnt>5</TotalOtherOrgCnt>
      <TransferToForeignCorpInd>1</TransferToForeignCorpInd>
      <InterestInForeignTrustInd>0</InterestInForeignTrustInd>
      <ForeignCorpOwnershipInd>0</ForeignCorpOwnershipInd>
      <PassiveForeignInvestmestCoInd>0</PassiveForeignInvestmestCoInd>
      <ForeignPartnershipInd>0</ForeignPartnershipInd>
      <BoycottCountriesInd>0</BoycottCountriesInd>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>PART I, LINE 2:</FormAndLineReferenceDesc>
        <ExplanationTxt>SUBRECIPIENTS ARE REQUIRED TO SUBMIT PROGRESS REPORTS, WHICH ARE REVIEWED BY RESPONSIBLE PROGRAM MANAGERS AND PROGRAM ADMINISTRATORS TO ENSURE THAT PROGRAM GOALS ARE ATTAINED IN ACCORDANCE WITH AGREEMENT REQUIREMENTS. THE RESPONSIBLE PROGRAM MANAGERS AND PROGRAM ADMINISTRATORS CONTACT SUBRECIPIENTS WITH QUESTIONS AND FOLLOW UP ON ANY CONCERNS. IN SOME CASES, SUBAWARD TERMS MAY REQUIRE SPECIFIED DELIVERABLES IN ADDITION TO, OR IN LIEU OF, TECHNICAL AND FINANCIAL REPORTS. DISCRETIONARY ON-SITE VISITS ARE ALSO CONDUCTED TO EVALUATE BOTH COMPLIANCE WITH THE SCIENTIFIC OBJECTIVES OF THE PROJECT AND APPROPRIATENESS OF THE SUBRECIPIENT'S ADMINISTRATIVE SYSTEMS AND PROCESSES.</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleF>
    <IRS990ScheduleI documentId="RetDoc1041900001">
      <GrantRecordsMaintainedInd>1</GrantRecordsMaintainedInd>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>701 20TH STREET SOUTH AB 1170</AddressLine1>
          <City>BIRMINGHAM</City>
          <State>AL</State>
          <ZIPCode>352940111</ZIPCode>
        </USAddress>
        <RecipientEIN>636005396</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>9121</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>UNIVERSITY OF WASHINGTON</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>4333 BROOKLYN AVE NE BOX 359472</AddressLine1>
          <City>SEATTLE</City>
          <State>WA</State>
          <ZIPCode>98195</ZIPCode>
        </USAddress>
        <RecipientEIN>916001537</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>13087</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>TULANE EDUCATIONAL FUND</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>1430 TULANE AVENUE TB-32</AddressLine1>
          <City>NEW ORLEANS</City>
          <State>LA</State>
          <ZIPCode>701122632</ZIPCode>
        </USAddress>
        <RecipientEIN>720423889</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>18000</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>JOHNS HOPKINS UNIVERSITY (JHU)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>3400 N CHARLES ST</AddressLine1>
          <City>BALTIMORE</City>
          <State>MD</State>
          <ZIPCode>21218</ZIPCode>
        </USAddress>
        <RecipientEIN>131687001</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>25887</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>3333 BURNET AVENUE</AddressLine1>
          <City>CINCINNATI</City>
          <State>OH</State>
          <ZIPCode>45229</ZIPCode>
        </USAddress>
        <RecipientEIN>310833936</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>27144</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>503 ROBERT GRANT DRIVE</AddressLine1>
          <City>SILVER SPRING</City>
          <State>MD</State>
          <ZIPCode>20910</ZIPCode>
        </USAddress>
        <RecipientEIN>520664528</RecipientEIN>
        <IRCSectionDesc>GOVERNMENT</IRCSectionDesc>
        <CashGrantAmt>27500</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>BIOPROCESS TECHNOLOGY CONSULTANTS INC (BPTC)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>12 GILL STREET SUITE 5450</AddressLine1>
          <City>WOBURN</City>
          <State>MA</State>
          <ZIPCode>01801</ZIPCode>
        </USAddress>
        <RecipientEIN>100002382</RecipientEIN>
        <IRCSectionDesc>N/A</IRCSectionDesc>
        <CashGrantAmt>27537</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>SEATTLE CHILDREN'S HOSPITAL</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>4800 SAND POINT WAY NE</AddressLine1>
          <City>SEATTLE</City>
          <State>WA</State>
          <ZIPCode>98105</ZIPCode>
        </USAddress>
        <RecipientEIN>911156519</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>30179</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>340 PANAMA ST</AddressLine1>
          <City>STANFORD</City>
          <State>CA</State>
          <ZIPCode>943056203</ZIPCode>
        </USAddress>
        <RecipientEIN>941156365</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>34235</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>UNIVERSITY OF WASHINGTON</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>4333 BROOKLYN AVE NE BOX 359472</AddressLine1>
          <City>SEATTLE</City>
          <State>WA</State>
          <ZIPCode>98195</ZIPCode>
        </USAddress>
        <RecipientEIN>916001537</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>39212</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>TUFTS UNIVERSITY</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>136 HARRISON AVENUE</AddressLine1>
          <City>BOSTON</City>
          <State>MA</State>
          <ZIPCode>02111</ZIPCode>
        </USAddress>
        <RecipientEIN>042103634</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>42096</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>503 ROBERT GRANT DRIVE</AddressLine1>
          <City>SILVER SPRING</City>
          <State>MD</State>
          <ZIPCode>20910</ZIPCode>
        </USAddress>
        <RecipientEIN>520664528</RecipientEIN>
        <IRCSectionDesc>GOVERNMENT</IRCSectionDesc>
        <CashGrantAmt>42258</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>OKLAHOMA STATE UNIVERSITY</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>203 WHITEHURST HALL</AddressLine1>
          <City>STILLWATER</City>
          <State>OK</State>
          <ZIPCode>74078</ZIPCode>
        </USAddress>
        <RecipientEIN>736017987</RecipientEIN>
        <IRCSectionDesc>GOVERNMENT</IRCSectionDesc>
        <CashGrantAmt>60000</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>JOHNS HOPKINS UNIVERSITY (JHU)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>3400 N CHARLES ST</AddressLine1>
          <City>BALTIMORE</City>
          <State>MD</State>
          <ZIPCode>21218</ZIPCode>
        </USAddress>
        <RecipientEIN>131687001</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>63215</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>JOHNS HOPKINS UNIVERSITY (JHU)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>3400 N CHARLES ST</AddressLine1>
          <City>BALTIMORE</City>
          <State>MD</State>
          <ZIPCode>21218</ZIPCode>
        </USAddress>
        <RecipientEIN>131687001</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>69353</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>UNIVERSITY OF PITTSBURGH</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>OFFICE OF RESEARCH 123 UNIVERSITY</AddressLine1>
          <AddressLine2>PLACE LOWER LOBBY</AddressLine2>
          <City>PITTSBURGH</City>
          <State>PA</State>
          <ZIPCode>15213</ZIPCode>
        </USAddress>
        <RecipientEIN>250965591</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>88084</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>FAMILY HEALTH INTERNATIONAL (FHI) 360</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>PO BOX 13950 2224 E NC HWY 54</AddressLine1>
          <City>DURHAM</City>
          <State>NC</State>
          <ZIPCode>27713</ZIPCode>
        </USAddress>
        <RecipientEIN>237413005</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>100000</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>SEATTLE CHILDREN'S HOSPITAL</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>4800 SAND POINT WAY NE</AddressLine1>
          <City>SEATTLE</City>
          <State>WA</State>
          <ZIPCode>98105</ZIPCode>
        </USAddress>
        <RecipientEIN>911156519</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>111816</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>1600 CLIFTON ROAD</AddressLine1>
          <City>ATLANTA</City>
          <State>GA</State>
          <ZIPCode>30333</ZIPCode>
        </USAddress>
        <RecipientEIN>586051157</RecipientEIN>
        <IRCSectionDesc>GOVERNMENT</IRCSectionDesc>
        <CashGrantAmt>123746</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>JOHNS HOPKINS UNIVERSITY (JHU)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>3400 N CHARLES ST</AddressLine1>
          <City>BALTIMORE</City>
          <State>MD</State>
          <ZIPCode>21218</ZIPCode>
        </USAddress>
        <RecipientEIN>131687001</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>138713</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>503 ROBERT GRANT DRIVE</AddressLine1>
          <City>SILVER SPRING</City>
          <State>MD</State>
          <ZIPCode>20910</ZIPCode>
        </USAddress>
        <RecipientEIN>520664528</RecipientEIN>
        <IRCSectionDesc>GOVERNMENT</IRCSectionDesc>
        <CashGrantAmt>139837</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>503 ROBERT GRANT DRIVE</AddressLine1>
          <City>SILVER SPRING</City>
          <State>MD</State>
          <ZIPCode>20910</ZIPCode>
        </USAddress>
        <RecipientEIN>520664528</RecipientEIN>
        <IRCSectionDesc>GOVERNMENT</IRCSectionDesc>
        <CashGrantAmt>160000</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>UNIVERSITY OF ALABAMA AT BIRMINGHAM</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>701 20TH STREET SOUTH AB 1170</AddressLine1>
          <City>BIRMINGHAM</City>
          <State>AL</State>
          <ZIPCode>352940111</ZIPCode>
        </USAddress>
        <RecipientEIN>636005396</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>183350</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>FINA BIOSOLUTIONS LLC</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>9610 MEDICAL CENTER DRIVE SUITE 200</AddressLine1>
          <AddressLine2>200</AddressLine2>
          <City>ROCKVILLE</City>
          <State>MD</State>
          <ZIPCode>20850</ZIPCode>
        </USAddress>
        <RecipientEIN>205448275</RecipientEIN>
        <IRCSectionDesc>N/A</IRCSectionDesc>
        <CashGrantAmt>193453</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>503 ROBERT GRANT DRIVE</AddressLine1>
          <City>SILVER SPRING</City>
          <State>MD</State>
          <ZIPCode>20910</ZIPCode>
        </USAddress>
        <RecipientEIN>520664528</RecipientEIN>
        <IRCSectionDesc>GOVERNMENT</IRCSectionDesc>
        <CashGrantAmt>199657</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>CHILDREN'S HOSPITAL BOSTON</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>300 LONGWOOD AVENUE</AddressLine1>
          <City>BOSTON</City>
          <State>MA</State>
          <ZIPCode>02115</ZIPCode>
        </USAddress>
        <RecipientEIN>042774441</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>200342</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>CHILDREN'S GMP LLC</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>262 DANNY THOMAS PLACE</AddressLine1>
          <City>MEMPHIS</City>
          <State>TN</State>
          <ZIPCode>38105</ZIPCode>
        </USAddress>
        <RecipientEIN>620646012</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>225889</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>NOVARTIS VACCINES AND DIAGNOSTICS</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>350 MASSACHUSETTS AVENUE</AddressLine1>
          <City>CAMBRIDGE</City>
          <State>MA</State>
          <ZIPCode>02139</ZIPCode>
        </USAddress>
        <RecipientEIN>942754624</RecipientEIN>
        <IRCSectionDesc>N/A</IRCSectionDesc>
        <CashGrantAmt>238463</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>JOHNS HOPKINS UNIVERSITY (JHU)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>3400 N CHARLES ST</AddressLine1>
          <City>BALTIMORE</City>
          <State>MD</State>
          <ZIPCode>21218</ZIPCode>
        </USAddress>
        <RecipientEIN>131687001</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>256204</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>503 ROBERT GRANT DRIVE</AddressLine1>
          <City>SILVER SPRING</City>
          <State>MD</State>
          <ZIPCode>20910</ZIPCode>
        </USAddress>
        <RecipientEIN>520664528</RecipientEIN>
        <IRCSectionDesc>GOVERNMENT</IRCSectionDesc>
        <CashGrantAmt>315451</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>MOUNT SINAI SCHOOL OF MEDICINE</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>ONE GUSTAVE L LEVY PLACE</AddressLine1>
          <City>NEW YORK</City>
          <State>NY</State>
          <ZIPCode>100296574</ZIPCode>
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        <RecipientEIN>136171197</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>575000</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
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      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>JOHNS HOPKINS UNIVERSITY (JHU)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>3400 N CHARLES ST</AddressLine1>
          <City>BALTIMORE</City>
          <State>MD</State>
          <ZIPCode>21218</ZIPCode>
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        <RecipientEIN>131687001</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>1113278</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>JOHNS HOPKINS UNIVERSITY (JHU)</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>3400 N CHARLES ST</AddressLine1>
          <City>BALTIMORE</City>
          <State>MD</State>
          <ZIPCode>21218</ZIPCode>
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        <RecipientEIN>131687001</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>1656608</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
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      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>NOVAVAX INC</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>20 FIRSTFIELD ROAD</AddressLine1>
          <City>ROCKVILLE</City>
          <State>MD</State>
          <ZIPCode>20878</ZIPCode>
        </USAddress>
        <RecipientEIN>222816046</RecipientEIN>
        <IRCSectionDesc>N/A</IRCSectionDesc>
        <CashGrantAmt>1950450</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
      </RecipientTable>
      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>LIQUIDIA TECHNOLOGIES INC</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>419 DAVIS DRIVE SUITE 100</AddressLine1>
          <City>DURHAM</City>
          <State>NC</State>
          <ZIPCode>27713</ZIPCode>
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        <RecipientEIN>201926605</RecipientEIN>
        <IRCSectionDesc>N/A</IRCSectionDesc>
        <CashGrantAmt>2149874</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
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      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>PATH</BusinessNameLine1>
        </RecipientBusinessName>
        <USAddress>
          <AddressLine1>2201 WESTLAKE AVE SUITE 200</AddressLine1>
          <City>SEATTLE</City>
          <State>WA</State>
          <ZIPCode>98121</ZIPCode>
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        <RecipientEIN>830431851</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>12702315</CashGrantAmt>
        <PurposeOfGrantTxt>GENERAL SUPPORT</PurposeOfGrantTxt>
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      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>INFECTIOUS DISEASE RESEARCH INSTITUTE (IDRI)</BusinessNameLine1>
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          <AddressLine1>1616 EASTLAKE AVENUE EAST</AddressLine1>
          <City>SEATTLE</City>
          <State>WA</State>
          <ZIPCode>98102</ZIPCode>
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        <RecipientEIN>911608978</RecipientEIN>
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      <RecipientTable>
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          <BusinessNameLine1>CHILDREN'S HOSPITAL BOSTON</BusinessNameLine1>
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          <AddressLine1>300 LONGWOOD AVE</AddressLine1>
          <City>BOSTON</City>
          <State>MA</State>
          <ZIPCode>02115</ZIPCode>
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        <RecipientEIN>042774441</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
        <CashGrantAmt>-26686</CashGrantAmt>
        <PurposeOfGrantTxt>PRODUCT DEVELOPMENT</PurposeOfGrantTxt>
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      <RecipientTable>
        <RecipientBusinessName>
          <BusinessNameLine1>DIAGNOSEARCH LIFE SCIENCES INC</BusinessNameLine1>
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          <AddressLine1>1140 AVENUE OF THE AMERICAS 9TH</AddressLine1>
          <AddressLine2>FLOOR</AddressLine2>
          <City>NEW YORK</City>
          <State>NY</State>
          <ZIPCode>10036</ZIPCode>
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        <RecipientEIN>030507787</RecipientEIN>
        <IRCSectionDesc>N/A</IRCSectionDesc>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>PART I, LINE 2:</FormAndLineReferenceDesc>
        <ExplanationTxt>SUBRECIPIENTS ARE REQUIRED TO SUBMIT PROGRESS REPORTS, WHICH ARE REVIEWED BY RESPONSIBLE PROGRAM MANAGERS AND PROGRAM ADMINISTRATORS TO ENSURE THAT PROGRAM GOALS ARE ATTAINED IN ACCORDANCE WITH AGREEMENT REQUIREMENTS. THE RESPONSIBLE PROGRAM MANAGERS AND PROGRAM ADMINISTRATORS CONTACT SUBRECIPIENTS WITH QUESTIONS AND FOLLOW UP ON ANY CONCERNS. IN SOME CASES, SUBAWARD TERMS MAY REQUIRE SPECIFIED DELIVERABLES IN ADDITION TO, OR IN LIEU OF, TECHNICAL AND FINANCIAL REPORTS. IN ADDITION, DISCRETIONARY ON-SITE VISITS ARE CONDUCTED TO EVALUATE BOTH COMPLIANCE WITH THE SCIENTIFIC OBJECTIVES OF THE PROJECT AND THE APPROPRIATENESS OF THE SUBRECIPIENT'S ADMINISTRATIVE SYSTEMS AND PROCESSES.</ExplanationTxt>
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        <ExplanationTxt>THE FORM 990 WAS PREPARED BY THE OUTSIDE ACCOUNTING FIRM USING INFORMATION PROVIDED BY PATH ACCOUNTING SERVICES STAFF. PATH SENIOR MANAGEMENT REVIEWED THE DRAFT FORM. A COPY OF THE FINAL 990 WAS SENT TO THE BOARD OF DIRECTORS FOR COMMENT. AFTER THE COMMENT PERIOD, THE CFO SIGNED THE RETURN.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION B, LINE 12C</FormAndLineReferenceDesc>
        <ExplanationTxt>PVS HAS A WRITTEN CONFLICT OF INTEREST POLICY UNDER WHICH ALL PVS BOARD MEMBERS AND OFFICERS MUST COMPLETE A CONFLICT OF INTEREST DISCLOSURE FORM EACH YEAR. PVS DOES NOT HAVE EMPLOYEES. PVS IS A SUPPORTING ORGANIZATION TO PATH WITHIN THE MEANING OF IRC SECTION 509(A)(3), AND PVS CONTRACTS WITH PATH FOR MANAGEMENT SERVICES. PATH HAS A WRITTEN CONFLICT OF INTEREST POLICY UNDER WHICH ALL PATH BOARD MEMBERS, OFFICERS, AND STAFF ABOVE A DESIGNATED LEVEL MUST COMPLETE A CONFLICT OF INTEREST DISCLOSURE FORM EACH YEAR. ALL PVS AND PATH DISCLOSURE FORMS ARE REVIEWED AND KEPT ON FILE. A CONFLICT MANAGEMENT PLAN IS DEVELOPED FOR ANY EMPLOYEE WITH A SIGNIFICANT ACTUAL OR PERCEIVED CONFLICT OF INTEREST.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION C, LINE 19</FormAndLineReferenceDesc>
        <ExplanationTxt>PVS'S FINANCIAL STATEMENTS, GOVERNING DOCUMENTS, AND CONFLICT OF INTEREST POLICY ARE MADE AVAILABLE TO THE PUBLIC UPON REQUEST.</ExplanationTxt>
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          <City>KYIV</City>
          <Country>UP</Country>
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        <PrimaryActivitiesTxt>REDUCE THE TB BURDEN IN UKRAINE</PrimaryActivitiesTxt>
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          <City>GENEVA</City>
          <Country>SZ</Country>
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      <TransferFromOtherOrgInd>0</TransferFromOtherOrgInd>
    </IRS990ScheduleR>
  </ReturnData>
</Return>