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      <RecipientTable>
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      <RecipientTable>
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        <AddressUS>
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          <City>CHAPEL HILL</City>
          <State>NC</State>
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      <Form990ScheduleJPartIII>
        <Identifier>PROVISIONS OF BENEFITS</Identifier>
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        <BondReferenceCd>A</BondReferenceCd>
        <ProcToUndertkCorrectiveAction>true</ProcToUndertkCorrectiveAction>
      </Form990ScheduleKPartV>
    </IRS990ScheduleK>
    <IRS990ScheduleL documentId="IRS990ScheduleL">
      <Form990ScheduleLPartIV>
        <NameOfInterestedPerson>
          <NamePerson>ORACLE CORPORATION</NamePerson>
        </NameOfInterestedPerson>
        <Relationship>SEE PART V</Relationship>
        <AmountOfTransaction>314868</AmountOfTransaction>
        <DescriptionOfTransaction>SOFTWARE LICENSES</DescriptionOfTransaction>
        <SharingOfRevenues>false</SharingOfRevenues>
      </Form990ScheduleLPartIV>
      <Form990ScheduleLPartIV>
        <NameOfInterestedPerson>
          <NamePerson>CAREGROUP INVESTMENT PARTNERSHIP</NamePerson>
        </NameOfInterestedPerson>
        <Relationship>SEE PART V</Relationship>
        <AmountOfTransaction>347942</AmountOfTransaction>
        <DescriptionOfTransaction>INVESTMENT MANAGEMENT FEE</DescriptionOfTransaction>
        <SharingOfRevenues>false</SharingOfRevenues>
      </Form990ScheduleLPartIV>
      <Form990ScheduleLPartIV>
        <NameOfInterestedPerson>
          <NamePerson>APPLE INC</NamePerson>
        </NameOfInterestedPerson>
        <Relationship>SEE PART V</Relationship>
        <AmountOfTransaction>804927</AmountOfTransaction>
        <DescriptionOfTransaction>COMPUTER EQUIPMENT</DescriptionOfTransaction>
        <SharingOfRevenues>false</SharingOfRevenues>
      </Form990ScheduleLPartIV>
      <Form990ScheduleLPartV>
        <Identifier>SCHEDULE L, PART IV, LINE 1</Identifier>
        <ReturnReference>NAME: ORACLE CORPORATION</ReturnReference>
        <Explanation>RELATIONSHIP: OFFICER OF ORACLE IS FAMILY MEMBER OF DIRECTOR.</Explanation>
      </Form990ScheduleLPartV>
      <Form990ScheduleLPartV>
        <Identifier>SCHEDULE L, PART IV, LINE 2</Identifier>
        <ReturnReference>NAME: CAREGROUP INVESTMENT PARTNERSHIP, LLP</ReturnReference>
        <Explanation>RELATIONSHIP: MEMBER OF BOARD OF MANAGERS OF CAREGROUP IS DIRECTOR.</Explanation>
      </Form990ScheduleLPartV>
      <Form990ScheduleLPartV>
        <Identifier>SCHEDULE L, PART IV, LINE 3</Identifier>
        <ReturnReference>NAME: APPLE, INC.</ReturnReference>
        <Explanation>RELATIONSHIP: CHAIRMAN OF APPLE IS DIRECTOR.</Explanation>
      </Form990ScheduleLPartV>
    </IRS990ScheduleL>
    <IRS990ScheduleM documentId="IRS990ScheduleM">
      <WorksOfArt />
      <ArtHistoricalTreasures />
      <ArtFractionalInterest />
      <BooksAndPublications />
      <ClothingAndHouseholdGoods />
      <CarsAndOtherVehicles />
      <BoatsAndPlanes />
      <IntellectualProperty />
      <SecuritiesPubliclyTraded>
        <NonCashCheckbox>X</NonCashCheckbox>
        <NumberOfContributions>3</NumberOfContributions>
        <NoncashContribsRptdF990>1281019</NoncashContribsRptdF990>
        <MethodOfDeterminingRevenues>MKT PRICE</MethodOfDeterminingRevenues>
      </SecuritiesPubliclyTraded>
      <SecuritiesCloselyHeldStock />
      <SecuritiesPrtnrshpTrustIntrsts />
      <SecuritiesMiscellaneous />
      <QualifiedContribHistStruct />
      <QualifiedContribOther />
      <RealEstateResidential />
      <RealEstateCommercial />
      <RealEstateOther />
      <Collectibles />
      <FoodInventory />
      <DrugsAndMedicalSupplies />
      <Taxidermy />
      <HistoricalArtifacts />
      <ScientificSpecimens />
      <ArchaeologicalArtifacts />
      <AnyPropertyThatMustBeHeld>false</AnyPropertyThatMustBeHeld>
      <ReviewProcessUnusualNCGifts>true</ReviewProcessUnusualNCGifts>
      <ThirdPartiesUsed>false</ThirdPartiesUsed>
    </IRS990ScheduleM>
    <IRS990ScheduleO documentId="IRS990ScheduleO">
      <GeneralExplanation>
        <Identifier>VOLUNTEERS</Identifier>
        <ReturnReference>FORM 990, PART I, LINE 6</ReturnReference>
        <Explanation>THE BROAD INSTITUTE DOES NOT FORMALLY TRACK VOLUNTEERS BUT HAS INCLUDED THE NUMBER OF BOARD MEMBERS AND COMMITTEE MEMBERS OF THE BOARD OF DIRECTORS THAT ARE UNCOMPENSATED. STATEMENT OF PROGRAM SERVICE ACCOMPLISHMENTS FORM 990, PART III, LINE 4A THE BROAD INSTITUTE OPERATES FOR EDUCATIONAL AND SCIENTIFIC PURPOSES AND IS A NEW KIND OF RESEARCH INSTITUTION AIMED AT PROPELLING THE TRANSFORMATION OF MEDICINE, BY BRINGING POWERFUL NEW APPROACHES TO BEAR ON THE UNDERSTANDING AND TREATMENT OF DISEASE. ITS RESEARCH PROGRAM ENCOMPASSES MULTIDISCIPLINARY AND INTEGRATED PROGRAMS IN MEDICAL AND POPULATION GENETICS, CANCER, INFECTIOUS DISEASE, METABOLIC AND PSYCHIATRIC DISEASES, AS WELL AS RESEARCH IN GENOME BIOLOGY, CELLULAR CIRCUITRY, COMPUTATIONAL BIOLOGY, CHEMICAL BIOLOGY AND NOVEL THERAPEUTICS. THERE WERE A TOTAL OF 587 PUBLICATIONS IN 2012 RESULTING FROM BROAD RESEARCH. THE BROAD INSTITUTE HOLDS AN ANNUAL SCIENTIFIC RETREAT, A TWO-DAY MEETING FEATURING PRESENTATIONS AND POSTERS ON A VARIETY OF RESEARCH PROJECTS ACROSS THE INSTITUTE, ATTENDED BY ALMOST A THOUSAND RESEARCHERS FROM THE BROAD COMMUNITY. THE BROAD DIRECTOR RECEIVED THE ALBANY MEDICAL PRIZE IN MEDICINE AND BIOMEDICAL RESEARCH TO RECOGNIZE FOUNDATIONAL CONTRIBUTIONS TO THE EFFORTS TO DECODE THE HUMAN GENETIC BLUEPRINT. THE BROAD'S EDUCATIONAL OUTREACH PROGRAM ENGAGES BOSTON-CAMBRIDGE AREA HIGH SCHOOL STUDENTS IN SCIENTIFIC RESEARCH BY PROVIDING SUMMER INTERNSHIPS AND SEMESTER-LONG RESEARCH PROJECTS. IN 2012, 12 STUDENTS PARTICIPATED IN A SUMMER INTERNSHIP AND 4 HIGH SCHOOL STUDENTS CAME TO BROAD THROUGH DIRECT CONTACT WITH SCIENTISTS. IN ADDITION, THE EDUCATIONAL PROGRAM SPONSORS CLASS VISITS TO THE BROAD AND HELD 4 SEMINARS FOR HIGH SCHOOL TEACHERS IN THE COURSE OF THE YEAR, WHICH APPROXIMATELY 80 TEACHERS ATTENDED LAST YEAR. IN 2012, THERE WERE 63 FIELD TRIPS TO BROAD THAT INCLUDED APPROXIMATELY 1300 STUDENTS AND 100 TEACHERS/ADULTS AND 3 VISITS TO SCHOOLS FOR PORTABLE LESSONS TO APPROXIMATELY 200 STUDENTS. BROAD ALSO SPONSORED 4 MIDSUMMER SCIENCE LECTURES WITH APPROXIMATELY 900 ATTENDEES. TO HELP INSPIRE YOUNG PEOPLE AND INCREASE THE NUMBER OF SCIENTISTS FROM DIVERSE BACKGROUNDS, THE BROAD'S DIVERSITY INITIATIVE IN SCIENTIFIC RESEARCH OFFERS PROGRAMS FOR MINORITIES AT DIFFERENT STAGES OF THEIR EDUCATION AND CAREERS. IN 2012, 16 HIGH SCHOOL STUDENTS, 12 UNDERGRADUATE STUDENTS, AND A FACULTY MEMBER PARTICIPATED IN THESE PROGRAMS. IN ADDITION, THIS PROGRAM ATTRACTED 160 HIGH SCHOOL STUDENTS WHO ATTENDED TWO LECTURES DURING THE SUMMER, 45 UNDERGRADUATE STUDENTS WHO ATTENDED A LECTURE ON COMPUTATIONAL BIOLOGY, AND ANOTHER 100 UNDERGRADUATE STUDENTS WHO ATTENDED A ONE-DAY WORKSHOP ON GRADUATE SCHOOL PREPARATION.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>RELATIONSHIPS AMONG</Identifier>
        <ReturnReference>FORM 990 PART VI, LINE 2</ReturnReference>
        <Explanation>PHILLIP SHARP IS AN EMPLOYEE OF THE MASSACHUSETTS INSTITUTE OF TECHNOLOGY AND L. RAFAEL REIF IS THE PRESIDENT OF THE MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THEREFORE THEY HAVE A BUSINESS RELATIONSHIP. THEY ARE BOTH DIRECTORS AT THE BROAD INSTITUTE. JEFFREY FLIER IS AN EMPLOYEE OF HARVARD UNIVERSITY AND DREW GILPIN FAUST IS THE PRESIDENT OF HARVARD UNIVERSITY, THEREFORE THEY HAVE A BUSINESS RELATIONSHIP. THEY ARE BOTH DIRECTORS AT THE BROAD INSTITUTE.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>MEMBERS</Identifier>
        <ReturnReference>FORM 990 PART VI, LINE 6</ReturnReference>
        <Explanation>THE MEMBERS OF THE BROAD INSTITUTE CONSIST OF THE MASSACHUSETTS INSTITUTE OF TECHNOLOGY ("MIT"), PRESIDENT AND FELLOWS OF HARVARD COLLEGE ("HARVARD") AND THE ELI AND EDYTHE BROAD FOUNDATION ("THE FOUNDATION").</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>DECISIONS OF THE GOVERNING BODY SUBJECT TO APPROVAL BY MEMBERS</Identifier>
        <ReturnReference>FORM 990 PART VI, LINE 7B</ReturnReference>
        <Explanation>BROAD MEMBERS (HARVARD, MIT AND THE BROAD FOUNDATION) EXERCISE ALL POWERS CONSISTENT WITH THE ACTIVITIES AND AFFAIRS OF THE BROAD INSTITUTE. THE MEMBERS HAVE ALL POWERS AND RIGHTS AS ARE VESTED IN THEM BY LAW, THE ARTICLES OF ORGANIZATION AND THE BY-LAWS, WHICH INCLUDE AMENDMENTS TO THE BY-LAWS AND ARTICLES OF INCORPORATION, THE ELECTION OR REPLACEMENT OF DIRECTORS, DISTRIBUTIONS OF THE ENDOWMENT PRIOR TO JULY 1, 2014 AND DISSOLUTION OF THE INSTITUTE. THE MEMBERS SHALL HOLD AN ANNUAL MEETING FOR ELECTION OF DIRECTORS AND FOR THE CONDUCT OF SUCH OTHER BUSINESS AS MAY COME BEFORE THE MEETING.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>REVIEW OF 990</Identifier>
        <ReturnReference>FORM 990, PART VI, LINE 11B</ReturnReference>
        <Explanation>THE BROAD INSTITUTE'S FORM 990 WAS PREPARED WITH THE ASSISTANCE OF THE INSTITUTE'S AUDITORS, PRICEWATERHOUSECOOPERS (PWC). THE DRAFT FORM 990 WAS PROVIDED TO THE INSTITUTE'S SENIOR MANAGEMENT AND AUDIT COMMITTEE FOR REVIEW AND COMMENT. THE FULL BOARD RECEIVED A COMPLETED COPY OF THE FORM 990 PRIOR TO THE FORM BEING FILED WITH THE IRS.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>CONFLICT OF INTEREST POLICY</Identifier>
        <ReturnReference>FORM 990, PART VI, LINE 12</ReturnReference>
        <Explanation>EACH DIRECTOR AND OFFICER HAS A DUTY TO PLACE THE INTEREST OF THE INSTITUTE FOREMOST IN ANY DEALING WITH THE INSTITUTE AND HAS A CONTINUING RESPONSIBILITY TO COMPLY WITH THE REQUIREMENTS OF THIS POLICY. EACH DIRECTOR AND OFFICER IS REQUIRED TO ANNUALLY ACKNOWLEDGE HIS OR HER FAMILIARITY WITH THIS POLICY AND DISCLOSE IN WRITING TO THE CHAIRMAN OF THE BOARD ANY EXISTING FINANCIAL OR OTHER MATERIAL INTERESTS SUBJECT TO THIS POLICY BY COMPLETING A CONFLICT OF INTEREST DISCLOSURE STATEMENT. THE CONFLICT OF INTEREST DISCLOSURE STATEMENTS ARE REVIEWED BY THE CHAIRMAN OF THE BOARD. ANY ISSUES NOT PREVIOUSLY DISCLOSED ARE REFERRED BY HIM OR HER TO THE BOARD OR APPROPRIATE COMMITTEE. THE CONFLICT OF INTEREST DISCLOSURE STATEMENTS ARE RETAINED IN THE CONFIDENTIAL FILES OF THE CHAIRMAN OF THE BOARD.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>COMPENSATION</Identifier>
        <ReturnReference>FORM 990, PART VI, LINE 15</ReturnReference>
        <Explanation>THE BROAD INSTITUTE ENGAGED AN OUTSIDE COMPENSATION CONSULTING FIRM (RADFORD) THAT SPECIALIZES IN THE BIOTECHNOLOGY FIELDS EARLY IN 2009 TO CONDUCT AN EXTERNAL BENCHMARK COMPENSATION STUDY OF SPECIFIC LEADERSHIP POSITIONS. RADFORD PRESENTED THEIR FINAL RECOMMENDATIONS AND FINDINGS TO THE COMPENSATION COMMITTEE WHO THEN REVIEWED AND CONTEMPORANEOUSLY DOCUMENTED THEIR DELIBERATIONS AND DECISIONS. THE TOP FIVE HIGHEST PAID EMPLOYEES AND ALL OFFICERS OTHER THAN THE PRESIDENT/CEO WERE INCLUDED IN RADFORD'S STUDY. THE BROAD INSTITUTE ENGAGED SULLIVAN COTTER AND ASSOCIATES, INC. TO CONDUCT AN INDEPENDENT STUDY FOR THE PRESIDENT/CEO'S COMPENSATION. THE STUDY FINDINGS WERE PRESENTED IN MAY OF 2012. THE COMPENSATION COMMITTEE THEN REVIEWED AND CONTEMPORANEOUSLY DOCUMENTED THEIR DELIBERATIONS AND DECISIONS. THE AMENDED TERMS OF THE PRESIDENT/CEO'S COMPENSATION PACKAGE WERE JOINTLY AGREED UPON BY BROAD, HARVARD AND MIT (THE INSTITUTE'S FOUNDING MEMBER ORGANIZATIONS).</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>PUBLIC DISCLOSURE OF DOCUMENTS</Identifier>
        <ReturnReference>FORM 990, PART VI, LINE 18</ReturnReference>
        <Explanation>THE FORM 990 IS MADE AVAILABLE UPON REQUEST AND ON GUIDESTAR.ORG.</Explanation>
      </GeneralExplanation>
      <GeneralExplanation>
        <Identifier>AVAILABILITY OF DOCUMENTS</Identifier>
        <ReturnReference>FORM 990, PART VI, LINE 19</ReturnReference>
        <Explanation>THE INSTITUTE'S AUDITED FINANCIAL STATEMENTS ARE ATTACHED TO THE ANNUALLY FILED MASSACHUSETTS FORM PC, WHICH IS AVAILABLE TO THE PUBLIC.</Explanation>
      </GeneralExplanation>
    </IRS990ScheduleO>
    <IRS990ScheduleR documentId="IRS990ScheduleR">
      <Form990ScheduleRPartI>
        <NameOfDisregardedEntity>
          <BusinessNameLine1>CLINICAL RESEARCH SEQ PLATFORM LLC</BusinessNameLine1>
        </NameOfDisregardedEntity>
        <AddressUS>
          <AddressLine1>SEVEN CAMBRIDGE CENTER</AddressLine1>
          <City>CAMBRIDGE</City>
          <State>MA</State>
          <ZIPCode>02142</ZIPCode>
        </AddressUS>
        <EIN>352469571</EIN>
        <PrimaryActivities>SEQUENCING</PrimaryActivities>
        <LegalDomicileState>MA</LegalDomicileState>
        <TotalIncome>0</TotalIncome>
        <EOYAssets>0</EOYAssets>
        <DirectControllingEntityName>
          <BusinessNameLine1>BROAD INST</BusinessNameLine1>
        </DirectControllingEntityName>
      </Form990ScheduleRPartI>
      <Form990ScheduleRPartI>
        <NameOfDisregardedEntity>
          <BusinessNameLine1>GENOME BRIDGE LLC</BusinessNameLine1>
        </NameOfDisregardedEntity>
        <AddressUS>
          <AddressLine1>SEVEN CAMBRIDGE CENTER</AddressLine1>
          <City>CAMBRIDGE</City>
          <State>MA</State>
          <ZIPCode>02142</ZIPCode>
        </AddressUS>
        <EIN>900984758</EIN>
        <PrimaryActivities>COMBINE DATA</PrimaryActivities>
        <LegalDomicileState>MA</LegalDomicileState>
        <TotalIncome>0</TotalIncome>
        <EOYAssets>0</EOYAssets>
        <DirectControllingEntityName>
          <BusinessNameLine1>BROAD INST</BusinessNameLine1>
        </DirectControllingEntityName>
      </Form990ScheduleRPartI>
    </IRS990ScheduleR>
  </ReturnData>
</Return>