2016-05-19T13:50:21-05:00 2015-09-30 910189318 MOSS ADAMS LLP 101 SECOND STREET SUITE 900 SAN FRANCISCO CA 94105 990 2014-10-01 770207331 PALO ALTO VETERANS INSTITUTE FOR RESEARCH PALO 6508583970 3801 MIRANDA AVENUE PALO ALTO CA 94304 KERSTIN LYNAM CEO 6508583970 2016-05-19 1 RICHARD CROGHAN P00089862 4159561500 2016-05-19 2014 2016-08-17 19:52:53Z KERSTIN LYNAM 3801 MIRANDA AVENUE PALO ALTO CA 94304 27288665 0 X WWW.PAVIR.ORG X 1988 CA ADVANCE VETERAN AND PUBLIC HEALTH THROUGH INNOVATIVE RESEARCH 12 4 331 4 0 0 22064702 24433121 2134015 2839296 17978 16248 32443 0 24249138 27288665 0 0 0 0 13407114 15153604 0 0 0 10902541 11354657 24309655 26508261 -60517 780404 8621232 9968460 2959987 3531805 5661245 6436655 X SEE SCHEDULE O. 0 0 957377 PREDICTING RESILIENCE IN THE HUMAN MICROBIOME - DAVID RELMAN, MDDR. DAVID RELMAN IS THE PROJECT DIRECTOR OF ONE OF PAVIR'S LARGEST RESEARCH PROJECTS. IT AIMS TO ANSWER QUESTIONS RELATING THE RESILIENCE IN THE HUMAN MICROBIOME, THE COLLECTIVE GENOMES OF THE MICROORGANISMS THAT RESIDE IN HUMANS. HUMANS HAVE CO-EVOLVED WITH COMPLEX, DYNAMIC MICROBIAL COMMUNITIES THAT PLAY ESSENTIAL ROLES IN NUTRITION, METABOLISM, IMMUNITY, AND NUMEROUS OTHER ASPECTS OF HUMAN PHYSIOLOGY. HENCE, MAINTENANCE AND RECOVERY OF KEY BENEFICIAL SERVICES BY THE MICROBIOTA IN THE FACE OF DISTURBANCE IS FUNDAMENTAL TO HEALTH. YET, STABILITY AND RESILIENCE VARY IN, AND BETWEEN INDIVIDUALS, AND ARE POORLY UNDERSTOOD. THIS PROJECT'S GOAL IS TO IDENTIFY FEATURES OF THE HUMAN MICROBIOME THAT PREDICT MICROBIAL COMMUNITY STABILITY AND RESILIENCE FOLLOWING DISTURBANCE. THE BREADTH AND MAGNITUDE OF THIS PROJECT'S IMPACT ARE SIGNIFICANT: THE STUDY TEAM ENVISIONS TESTS TO PREDICT MICROBIAL COMMUNITY RESPONSES TO DISTURBANCE, AND PROCEDURES TO STABILIZE OR RESTORE BENEFICIAL MICROBIAL INTERACTIONS AS NEEDED. A PREDICTIVE UNDERSTANDING OF THE STABILITY AND RESILIENCE OF THE GUT MICROBIOTA WILL ADVANCE THE RATIONAL PRACTICE OF MEDICINE. 930465 TREATING PTSD IN DIVERSE POPULATIONSPOST TRAUMATIC STRESS DISORDER (PTSD) IS TYPICALLY THOUGHT OF AS AFFLICTING RETURNING MILITARY AND VETERANS WHO HAVE ENDURED EXTREME WARTIME STRESSORS THAT CHALLENGE THEIR VALUE SYSTEM AND MENTAL HEALTH. BUT PTSD IS MUCH MORE PREVALENT AND IS MORE VARIED THAN THAT. MANY INDIVIDUALS WHO SUFFER FROM PTSD HAVE NO TIES TO THE MILITARY AND DEVELOP PTSD AS A RESULT OF CIVILIAN VIOLENCE IN THE COMMUNITY, IN THE FAMILY AND IN INTIMATE RELATIONSHIPS AND SEEK TREATMENT IN COMMUNITY MENTAL HEALTH SETTINGS. IN ADDITION, MANY VETERANS SEEK THEIR CARE OUTSIDE OF THE VA. THIS IS WHY IT IS IMPORTANT TO EVALUATE THE EFFECTIVENESS OF AN EVIDENCE BASED PTSD TREATMENT THAT INCLUDES FLEXIBLE DELIVERY STRATEGIES FOR DIFFERENT CIRCUMSTANCES IN THE CONTEXT OF THE BROADER COMMUNITY. IN THIS PAVIR ADMINISTERED STUDY, DR. CLOITRE AND HER RESEARCH TEAM WILL ASSESS THE EFFECTIVENESS OF A TREATMENT REFINED HERE IN PALO ALTO, AGAINST THE TREATMENT AS USUAL (TAU) IN THE CONTEXT OF EVERY DAY CLINICAL CARE IN COMMUNITY MENTAL HEALTH SETTINGS. OVER 300 STUDY PARTICIPANTS HAVE BEEN ENROLLED TO BENEFIT FROM THIS NOVEL AND FLEXIBLE CARE OPTION. SOME OF THE STUDY'S PROMISING RESULTS HAVE BEEN PUBLISHED DURING THIS FISCAL YEAR TO EXTEND THE STUDY'S EXPERIENCE TO A WIDER PUBLIC AND TO ENCOURAGE ADOPTATION OF THE NEW CARE OPTION IN ADDITIONAL PUBLIC CARE SETTINGS. 750522 HYPOSALIVATION AND THE HUMAN ORAL MICROBIOME, DAVID RELMAN, MDREDUCED SALIVARY FLOW RATE, OR HYPOSALIVATION, IS A COMMON DISORDER ASSOCIATED WITH AN INCREASED INCIDENCE OF ATYPICAL BUT SEVERE CORONAL AND ROOT SURFACE DENTAL CARIES, AS WELL AS A PROFOUND REDUCTION IN QUALITY OF LIFE. ALTHOUGH IT IS KNOWN THAT THE MICROBIAL COMMUNITIES OF THE EXPOSED TOOTH SURFACE PLAY A CRITICAL ROLE IN CARIES FORMATION, LITTLE IS KNOWN ABOUT THE COMMUNITIES ASSOCIATED WITH HYPOSALIVATION AND THEIR ROLE IN ATYPICAL CARIES FORMATION, ESPECIALLY ON A TOOTH-SPECIFIC BASIS. WE PROPOSE TO STUDY TWO OF THE MOST COMMON CAUSES OF HYPOSALIVATION, MEDICATION USE AND THE AUTOIMMUNE CONDITION, SJOGREN'S SYNDROME, IN ORDER TO DEFINE AND CHARACTERIZE, FOR THE FIRST TIME, CHANGES IN SUPRAGINGIVAL MICROBIAL COMMUNITIES AT MULTIPLE SPATIAL AND TEMPORAL SCALES IN ACUTE AND CHRONIC STATES OF HYPOSALIVATION, AND TO DEVELOP NEW DIAGNOSTIC AND PROGNOSTIC MARKERS FOR HYPOSALIVATION-ASSOCIATED CARIES. 20245102 2839296 THANKS TO STRONG COLLABORATIVE TIES PAVIR IS PRIVILEGED TO WORK WITH A LARGE COMMUNITY OF UNIQUELY TALENTED MEDICAL RESEARCHERS ACROSS A BROAD SPECTRUM OF RESEARCH AREAS AS WE FULFILL OUR MISSION OF ADVANCING VETERANS AND PUBLIC HEALTH THROUGH INNOVATIVE RESEARCH.THE RANGE OF RESEARCH ACTIVITIES IS BROAD AND INCLUDES SPECIAL EMPHASIS ON MAJOR DISEASES CATEGORIES, ALL OF WHICH ARE PREVALENT IN THE VA'S PATIENT POPULATION. THESE INCLUDE CARDIOVASCULAR MEDICINE, MENTAL HEALTH, CHRONIC INFLAMMATORY DISEASE, STEM CELL/REGENERATIVE MEDICINE, PAIN, SLEEP DISORDERS, AND MANY OTHERS. IN ADDITION TO DISEASE SPECIFIC RESEARCH, PAVIR IS ALSO ENGAGED IN SUPPORTING RESEARCH AIMED AT OPTIMIZING HEALTH CARE. PAVIR'S RESEARCH PORTFOLIO INCLUDES COMPARATIVE STUDIES IN WHICH RESEARCH TEAMS ARE LEARNING WHICH TREATMENTS ARE SUPERIOR TO OTHERS, HOW TO AUGMENT OR IMPROVE STANDARD OF CARE, AS WELL AS HOW TO ENHANCE THE OPERATION OF HEALTH CARE. 20245102 2839296 22883466 1 1 0 1 0 0 0 0 0 0 1 0 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 49 0 1 331 1 0 0 0 0 0 0 0 0 0 0 X 12 4 0 0 0 0 0 0 0 1 0 0 0 1 1 1 1 1 1 1 1 0 CA X LILY IBRAGIMOV 6508583970 3801 MIRANDA AVENUE PALO ALTO CA 94304 ELIZABETH JOYCE FREEMAN STATUTORY VA DIRECTOR 0.50 40.00 X 0 0 0 PHILLIP L JELSMA DIRECTOR, AUDIT COMMITTEE MEMBER 0.50 X 0 0 0 JOHN POLLARD STATUTORY VA DIRECTOR, AUDIT COMMITTEE MEMBER 0.50 40.00 X 0 0 0 LAWRENCE LEUNG STATUTORY VA DIRECTOR, SECRETARY/TREASURER 1.00 40.00 X 0 0 0 DAVID CLARK DIRECTOR, BOARD CHAIR (THRU 7/1/15) 1.00 40.00 X 0 0 0 ODETTE HARRIS SINCE 92315 DIRECTOR 0.50 40.00 X 0 0 0 CHARLIE CONZ SINCE 11415 DIRECTOR 0.50 X 0 0 0 ROBERTA OKA THRU 083115 DIRECTOR 0.50 40.00 X 0 0 0 BARCLAY KAMB THRU 092615 STATUTORY NON-FEDERAL DIRECTOR 0.50 X 0 0 0 CAROL OLSON STATUTORY NON-FEDERAL DIRECTOR 0.50 X 0 0 0 PHILIP TSAO STATUTORY VA DIRECTOR 1.00 40.00 X 0 0 0 MARK NICOLLS SINCE 7215 DIRECTOR, BOARD CHAIR 1.00 40.00 X 0 0 0 KERSTIN LYNAM CEO 40.00 X 258233 0 15759 BONNIE LIANG SINCE 7815 CFO 40.00 X 0 0 0 MARY THORNTON THRU 53115 COO 40.00 X 157245 0 21645 STEPHANY HENSEY DATABASE ADMINISTRATOR 40.00 X 139442 0 20177 BRIAN DOHERTY IT MANAGER 40.00 X 134588 0 17062 LILY IBRAGIMOV CONTROLLER 40.00 X 123910 0 18136 MICHELLE HERNANDEZ HR DIRECTOR 40.00 X 119272 0 17697 IRINA GORODETSKAYA PROGRAM MANAGER I 40.00 X 117165 0 13223 1049855 0 123699 12 0 1 0 0 23028368 1404753 8295 24433121 MEDICAL RESEARCH 541700 2200708 2200708 GOVT FEES & CONTRACTS 541700 638588 638588 2839296 16248 16248 27288665 2839296 0 16248 514694 514694 11846056 10353754 1492302 585882 529367 56515 1254343 1043100 211243 952629 808749 143880 40170 3287 36883 101200 101200 1709712 1199813 509899 107270 41929 65341 603417 382619 220798 213358 195146 18212 119005 119005 195181 152522 42659 324047 312266 11781 40669 40669 RESEARCH MATERIAL COSTS 3671789 3671789 SUBRECIPIENTS 1927433 1927433 PERSONNEL COST 1624088 1489095 134993 EQUIPMENT RENTAL & MAIN 443185 439894 3291 234133 213698 20435 26508261 22883466 3624795 0 1019700 2167073 3568124 3475791 3111896 3038299 48485 212068 2807640 1739011 866427 1068629 6600 6600 8621232 9968460 769292 1049555 859922 1193271 1330773 1288979 2959987 3531805 X 4815714 5449542 845531 987113 5661245 6436655 8621232 9968460 780404 -4994 0 X 0 1 X 1 1 1 X VA PALO ALTO HEALTH CARE SYSTEM PALO ALTO CA RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 0 0 0 0 0 1 435 0 0 0 435 0 PART II-B, LINE 1: OUR ORGANIZATION PAID MEMBERSHIP DUES TO THE NATIONAL ASSOCIATION OF VETERANS RESEARCH AND EDUCATION FOUNDATIONS (NAVREF). THE REPORTED FIGURE IS THE PORTION OF THOSE DUES WHICH NAVREF ESTIMATES WENT TOWARD ITS LOBBYING ACTIVITIES. 2807640 1739011 1068629 1068629 PAYROLL PAYABLE 513556 ACCRUED VACATION 719130 OTHER ACCRUED LIABILITIES 56293 1288979 X 27283671 -4994 -4994 27288665 0 27288665 26508261 0 26508261 0 26508261 PART X, LINE 2: PALO ALTO VETERANS INSTITUTE FOR RESEARCH IS A NONPROFIT CORPORATION EXEMPT FROM FEDERAL INCOME TAX UNDER INTERNAL REVENUE CODE SECTION 501(C)(3) AND STATE INCOME TAX UNDER CALIFORNIA REVENUE AND TAXATION CODE SECTION 23701D. THE ORGANIZATION QUALIFIES FOR THE CHARITABLE CONTRIBUTION DEDUCTION UNDER IRC SECTION 170(B)(1)(A)(III) AND HAS BEEN CLASSIFIED AS AN ORGANIZATION THAT IS NOT A PRIVATE FOUNDATION UNDER SECTION 509(A)(1). AS OF SEPTEMBER 30, 2015, THE ORGANIZATION HAD NO UNRECOGNIZED TAX BENEFITS OR UNCERTAIN TAX POSITIONS REQUIRING ACCRUAL. THEREFORE, NO PROVISION FOR INCOME TAXES HAS BEEN PROVIDED IN THE FINANCIAL STATEMENTS. X X X 0 0 0 0 0 0 0 0 0 KERSTIN LYNAM CEO 258233 0 0 0 0 0 9685 0 6074 0 273992 0 0 0 MARY THORNTON THRU 53115 COO 157245 0 0 0 0 0 15533 0 6112 0 178890 0 0 0 STEPHANY HENSEY DATABASE ADMINISTRATOR 139442 0 0 0 0 0 14065 0 6112 0 159619 0 0 0 BRIAN DOHERTY IT MANAGER 134588 0 0 0 0 0 13728 0 3334 0 151650 0 0 0 990, PART III, LINE 1 MISSION STATEMENT: THE MISSION OF THE PALO ALTO VETERANS INSTITUTE FOR RESEARCH (PAVIR) IS ADVANCING VETERANS AND PUBLIC HEALTH THROUGH INNOVATIVE RSEARCH. PAVIR WORKS WITH MORE THAN 100 RESEARCHERS AND 250 STAFF TO ADDRESS BASIC SCIENCE AND CLINICAL RESEARCH QUESTIONS TO REALIZE ITS MISSION. PAVIR'S RESEARCH SPANS THE INVESTIGATION OF DISEASES IN THE LABORATORY TO TESTING NEW DRUG TREATMENTS, TO DEVELOPING IMPROVED MODELS OF HEALTH CARE DELIVERY. PAVIR'S MEDICAL RESEARCH COVERS MENTAL HEALTH INCLUDING POST TRAUMATIC STRESS DISORDER AND TRAUMATIC BRAIN INJURY, GERIATRIC MEDICINE, REHABILITATION, SLEEP, AND OTHER MEDICAL SPECIALTITES. IN ADDITION TO RESEARCHERS' APPOINTMENT AT THE VA PALO ALTO HEALTH CARE SYSTEM, MOST HOLD DUAL APPOINTMENTS AT THE STANFORD UNIVERSITY SCHOOL OF MEDICINE. FORM 990, PART VI, SECTION A, LINE 8B IN ACCORDANCE WITH THE BYLAWS THE BOARD HAS PREPARED MINUTES THAT ARE APPROVED BY ALL MEMBERS DOCUMENTING ITS ACTIONS. STANDING COMMITTES ARE NOT AUTHORIZED TO ACT ON BEHALF OF THE GOVERNING BODY. FORM 990, PART VI, SECTION B, LINE 11 THE FORM 990 HAS BEEN PROVIDED TO ALL BOARD MEMBERS FOR THEIR REVIEW AND APPROVAL PRIOR TO THE FILING OF ALL RELATED TAX FORMS. FORM 990, PART VI, SECTION B, LINE 12C EACH YEAR, PAVIR'S DIRECTORS AND OFFICERS MUST REVIEW PAVIR'S CONFLICT OF INTEREST POLICY AND COMPLETE AND SIGN A CONFLICT OF INTEREST DISCLOSURE QUESTIONNAIRE, DISCLOSING ANY POTENTIAL AREAS OF CONFLICT OF INTEREST OCCURRING DURING THE PRECEDING 12 MONTHS. FORM 990, PART VI, SECTION B, LINE 15 THE PAVIR HR DIRECTOR CONDUCTED A COMPENSATION STUDY FOR EXECUTIVE POSITIONS, UTILIZING DATA FROM COMPARABLE ORGANIZATIONS BASED ON GEOGRAPHY, INDUSTRY AND REVENUE. THE STUDY WAS PRESENTED TO THE BOARD OF DIRECTORS FOR REVIEW AND APPROVAL. THE BOARD CONVENED AN EXECUTIVE SESSION, DURING WHICH THE COMPENSATION DATA WAS USED TO MAKE EXECUTIVE COMPENSATION DECISIONS. THE BOARD DECISIONS REGARDING EXECUTIVE COMPENSATION WAS DOCUMENTED IN FILE. FORM 990, PART VI, SECTION C, LINE 19 THE AUDITED FINANCIAL STATEMENTS, ORGANIZING/GOVERNING DOCUMENTS, AND CONFLICT OF INTEREST POLICY ARE AVAILABLE UPON WRITTEN REQUEST. FORM 990 PART VII; SCH. J, PART II; SCH. L, PART IV; & SCH. R, PART V, 1N COMPENSATION FROM RELATED ORGANIZATION: ON 4/26/16 PALO ALTO VETERANS INSTITUTE FOR RESEARCH WROTE TO EACH OF THE 8 BOARD MEMBERS WHO ARE COMPENSATED BY THE VA PALO ALTO HEALTH CARE SYSTEM REQUESTING PERMISSION TO OBTAIN HIS/HER COMPENSATION INFORMATION FOR THE TAX YEAR ENDING 12/31/2014. IN RESPONSE, ALL BOARD MEMBERS DECLINED IN WRITING TO PROVIDE THEIR COMPENSATION INFORMATION. VA PALO ALTO HEALTH CARE SYSTEM 3801 MIRANDA AVENUE PALO ALTO CA 94304 941179505 TEACHING HOSPITAL, PROVIDING A FULL RANGE OF PATIENT CARE SERVICES CA 501(C)(1) N/A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 VA PALO ALTO HEALTH CARE SYSTEM N 165137 FAIR MARKET VALUE