2017-05-23T17:51:18-05:00 2016-09-30 910189318 Moss Adams LLP 101 Second Street Suite 900 San Francisco CA 94105 990 2015-10-01 770207331 Palo Alto Veterans Institute for Research PALO 6508583970 3801 Miranda Avenue Palo Alto CA 94304 Bonnie Liang CFO/COO 6508583970 2017-05-23 1 Richard Croghan P00089862 4159561500 2017-05-23 2015 2021-01-29 14:40:06Z Kerstin Lynam 3801 Miranda Avenue Palo Alto CA 94304 28236469 0 X www.pavir.org X 1988 CA ADVANCE VETERAN AND PUBLIC HEALTH THROUGH INNOVATIVE RESEARCH 9 2 338 9 0 0 24433121 23247661 2839296 4963804 16248 2208 0 6300 27288665 28219973 0 0 0 0 15153604 15765025 0 0 0 11354657 11121114 26508261 26886139 780404 1333834 9968460 10945542 3531805 3175921 6436655 7769621 X See Schedule O. 0 0 1528327 PREDICTING RESILIENCE IN THE HUMAN MICROBIOME - DAVID RELMAN, MDDR. DAVID RELMAN IS THE PROJECT DIRECTOR OF ONE OF PAVIR'S LARGEST, MULTI-YEAR RESEARCH PROJECTS. IT IS ON THE CUTTING EDGE OF EXAMINING THE HUMAN MICROBIOME, THE COLLECTIVE GENOMES OF THE MICRO-ORGANISMS THAT RESIDE IN HUMANS. SPECIFICALLY, THE PROJECT AIMS TO ANSWER QUESTIONS RELATING TO THE RESILIENCE IN THE HUMAN MICROBIOME. HUMANS HAVE CO-EVOLVED WITH COMPLEX, DYNAMIC MICROBIAL COMMUNITIES THAT PLAY ESSENTIAL ROLES IN NUTRITION, METABOLISM, IMMUNITY, AND NUMEROUS OTHER ASPECTS OF HUMAN PHYSIOLOGY. HENCE, MAINTENANCE AND RECOVERY OF KEY BENEFICIAL SERVICES BY THE MICROBIOTA IN THE FACE OF DISTURBANCE IS FUNDAMENTAL TO HEALTH. THE GOAL IS TO IDENTIFY FEATURES OF THE HUMAN MICROBIOME THAT PREDICT MICROBIAL COMMUNITY STABILITY AND RESILIENCE FOLLOWING DISTURBANCE. THE BREADTH AND MAGNITUDE OF THIS PROJECT'S IMPACT ARE SIGNIFICANT: THE STUDY TEAM TESTS TO PREDICT MICROBIAL COMMUNITY RESPONSES TO DISTURBANCE, AND WORKS ON PROCEDURES TO STABILIZE OR RESTORE BENEFICIAL MICROBIAL INTERACTIONS AS NEEDED. A PREDICTIVE UNDERSTANDING OF THE STABILITY AND RESILIENCE OF THE GUT MICROBIOTA WILL ADVANCE THE RATIONAL PRACTICE OF MEDICINE. THIS PROJECT'S PARTICIPANT RECRUITMENT IS NEARLY COMPLETE, DATA COLLECTION HAS BEEN OPTIMIZED RESULTING IN REDUCTION OF TECHNICAL VARIANCE AND REDUCED COMPLEXITY OF THE OVERALL PROTOCOL. AN ADDITIONAL AREA OF RECENT PROGRESS HAS BEEN IN DEVELOPING STANDARDS TO USE A LIQUID HANDLING ROBOT TO FACILITATE SEVERAL STEPS OF THE OVERALL WORK FLOW. 809841 800351 DEFENSE AND VETERANS BRAIN INJURY CENTER (DVBIC) - ODETTE HARRIS, M.D., M.P.H.THE DEFENSE AND VETERANS BRAIN INJURY CENTER (DVBIC) IS A KEY COMPONENT OF THE U.S. MILITARY HEALTH SYSTEM, AND FUNCTIONS AS THE TRAUMATIC BRAIN INJURY (TBI) OPERATIONAL COMPONENT OF THE DEFENSE CENTERS OF EXCELLENCE FOR PSYCHOLOGICAL HEALTH AND TRAUMATIC BRAIN INJURY (DCOE). FOUNDED IN 1992 BY THE UNITED STATES CONGRESS, DVBIC'S RESPONSIBILITIES HAVE GROWN AS ITS MULTI-SITE NETWORK COMPRISING CLINICAL RESEARCH, EDUCATION, OUTREACH, AND CARE COORDINATION AND TREATMENT HAS EXPANDED. DVBIC'S MISSION IS TO ASSIST THE DEPARTMENT OF DEFENSE (DOD) AND VA IN OPTIMIZING CARE FOR ACTIVE DUTY MILITARY, THEIR BENEFICIARIES, AND VETERANS WHO HAVE SUSTAINED A TBI AT HOME AND IN THE DEPLOYED SETTING, THROUGH STATE-OF-THE-ART CLINICAL CARE, INNOVATIVE CLINICAL RESEARCH INITIATIVES, EDUCATIONAL PROGRAMS, AND SUPPORT FOR FORCE HEALTH PROTECTION SERVICES. PROJECTS UNDERTAKEN IN PALO ALTO INCLUDE POST-ACUTE MANAGEMENT OF HEAD INJURIES IN MILITARY AND VA HOSPITALS; LONG-TERM OUTCOME AFTER TBI; PROSPECTIVE TBI CLINICAL TRACKING STUDY, STRUCTURED TELEPHONIC TESTING 5-15 YEARS AFTER TBI; WOMEN AND TRAUMATIC BRAIN INJURY: RETROSPECTIVE COHORT ANALYSIS; AND REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION (RTMS) TO IMPROVE COGNITIVE FUNCTION IN TBI. 761379 A BIOORTHOGONAL APPROACH TO STUDY MAMMALIAN AGING - TONY WYSS-CORAY, PH.D. AGING IS THE MAJOR RISK FACTOR FOR A MAJORITY OF THE LEADING CAUSES OF DEATLH IN THE US INCLUDING HEART DISEASE, CANCER, STROKE AND DEMENTIA. DR. WYSS-CORAY'S LABORATORY IS WORKING ON A NEW TECHNOLOGY WHICH WILL ENABLE RESEARCHER TO IDENTIFY FACTORS THAT CAN REJUVENATE THE BRAIN AND OTHER ORGANS AND ACCELERATE OUR UNDERSTANDING OF THE BASIC BIOLOGY OF AGING. THE WYSS-CORAY LABORATORY IS POISED TO FACILITATE THE IDENTIFICATON, LOCALIZATION, AND TRACKING OF FACTORS SECREATED FROM SPECIFIC ORGANELLES, CELL TYPES, OR ORGANS IN VIVO. THIS IS TRULY INNOVATIVE AND HAS NOT BEEN DONE BEFORE. THE POTENTIAL APPLICATIONS OF THIS TECHNOLOGY FOR DISEASE AND BIOLOGICAL RESEARCH IN GENERAL COULD BE ENORMOUS, AND WILL GET US CLOSER TO ANSWERING FUNDAMENTAL QUESTIONS ON WHAT CONTROLS ORGANISMAL AGING. THESE QUESTIONS INCLUDE WHETHER AGING STARTS IN ONE TISSUE AND SPREAD TO ANOTHER, OR STARTS IN ONE CELL TYPE AND SPREAD TO OTHER CELLS AND TISSUES, OR STARTS SIMULTANEOUSLY IN ALL CELLS, OR DRIVEN BY OTHER FACTORS. THIS PROJECT FOLLOWS A PREVIOUS GROUNDBREAKING DISCOVERY IN DR. WYSS-CORAY'S LABORATORY THAT SOLUBLE, HEAT LABILE FACTORS IN BLOOD PLASMA ARE SUFFICIENT TO ACCELERATE BRAIN AGING OR REGENERATE AND REJUVINATE OLD BRAINS. 19717790 4163453 PAVIR IS PRIVILEGED TO WORK WITH A LARGE COMMUNITY OF UNIQUELY TALENTED MEDICAL RESEARCHERS ACROSS A BROAD SPECTRUM OF RESEARCH AREAS AS WE FULFILL OUR MISSION OF ADVANCING VETERANS AND PUBLIC HEALTH THROUGH INNOVATIVE RESEARCH.THE RANGE OF RESEARCH ACTIVITIES IS BROAD AND INCLUDES SPECIAL EMPHASIS ON MAJOR DISEASE CATEGORIES, ALL OF WHICH ARE PREVALENT IN THE VA'S PATIENT POPULATION. THESE INCLUDE CARDIOVASCULAR MEDICINE, MENTAL HEALTH, CHRONIC INFLAMMATORY DISEASE, STEM CELL/REGENERATIVE MEDICINE, PAIN, SLEEP DISORDERS, AND MANY OTHERS. IN ADDITION TO DISEASE SPECIFIC RESEARCH, PAVIR IS ENGAGED IN SUPPORTING RESEARCH AIMED AT ENHANCING HEALTH CARE. PAVIR'S RESEARCH PORTFOLIO INCLUDES COMPARATIVE STUDIES IN WHICH RESEARCH TEAMS ARE LEARNING WHICH TREATMENTS ARE SUPERIOR TO OTHERS, HOW TO AUGMENT OR IMPROVE STANDARD OF CARE, AS WELL AS HOW TO ENHANCE THE OPERATION OF HEALTH CARE. FURTHERMORE, PAVIR IS SUPPORTING EDUCATIONAL ACTIVITIES, ESPECIALLY IN AREAS OF ADVANCING CLINICAL CARE FOR VETERANS AND FOSTERING THE PROFESSIONAL DEVELOPMENT OF OUR EXPERT STAFF. 19717790 4163453 22817337 1 1 0 1 0 0 0 0 0 0 1 0 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 49 0 1 338 1 0 0 0 0 0 0 0 0 0 0 X 9 2 0 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 1 0 CA X Lily Ibragimov 6508583970 3801 Miranda Avenue Palo Alto CA 94304 MARK NICOLLS DIRECTOR, BOARD CHAIR 1.00 40.00 X 0 0 0 LAWRENCE LEUNG STATUTORY VA DIRECTOR, SECRETARY/TREASURER 1.00 40.00 X 0 0 0 PHILIP TSAO Statutory VA DIRector, CHAIR OF AUDIT Committee 1.00 40.00 X 0 0 0 THOMAS J FITZGERALD III STATUTORY VA DIRECTOR 0.50 40.00 X 0 0 0 JOHN POLLARD STATUTORY VA DIRECTOR, AUDIT Committee MEMBER 0.50 40.00 X 0 0 0 DAVID CLARK VA DIRECTOR 1.00 40.00 X 0 0 0 ODETTE HARRIS VA DIRECTOR 0.50 40.00 X 0 0 0 CHARLIE CONZ DIRECTOR 0.50 X 0 0 0 PHILLIP L JELSMA DIRECTOR 0.50 X 0 0 0 ELIZABETH JOYCE FREEMAN Statutory VA DIRECTOR (Thru 06/2016) 0.50 40.00 X 0 0 0 CAROL OLSON DIRECTOR (Thru 06/2016) 0.50 X 0 0 0 KERSTIN LYNAM CEO 40.00 X 250331 0 35881 BONNIE LIANG CFO/COO 40.00 X 66518 0 2764 MARY THORNTON IT Director 40.00 X 135002 0 19959 STEPHANIE L HENSEY DATABASE MANAGER I 40.00 X 129315 0 22843 MICHELLE HERNANDEZ HR DIRECTOR (Thru 02/2016) 40.00 X 120603 0 21022 LILY IBRAGIMOV CONTROLLER 40.00 X 115197 0 18077 WEN AMY TIAN RESEARCH SCIENTIST II 40.00 X 117899 0 17994 934865 0 138540 12 0 1 0 0 21771514 1476147 588 23247661 Medical Research 541700 3885338 3885338 GOVT FEES & CONTRACTS 541700 1078466 1078466 4963804 18704 18704 16496 -16496 -16496 -16496 Miscellaneous Revenue 541700 6300 6300 6300 28219973 4963804 0 8508 526954 526954 12496177 10543634 1952543 619243 486133 133110 1083546 905314 178232 1039105 853896 185209 41090 10034 31056 109392 109392 1561317 1123630 437687 73273 32262 41011 433715 241097 192618 158771 145663 13108 144562 144562 203735 173184 30551 424076 412292 11784 43955 43955 Research Material Costs 3833775 3833682 93 Subrecipients 1752243 1752243 Personnel Cost 1725408 1595400 130008 Equipment Maintenance 417580 416662 918 198222 147649 50573 26886139 22817337 4068802 0 2167073 1506687 3475791 4088935 3038299 3902244 212068 315443 2993915 1861682 1068629 1132233 6600 0 9968460 10945542 1049555 962519 1193271 758474 1288979 1454928 3531805 3175921 X 5449542 6811348 987113 958273 6436655 7769621 9968460 10945542 1333834 -868 0 X 0 1 X 1 1 1 X va palo alto health care system palo alto CA RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 0 0 0 0 0 1 435 0 0 0 435 0 Part II-B, Line 1: Our organization paid membership dues to the National Association of Veterans Research and Education Foundations (NAVREF). The reported figure is the portion of those dues which NAVREF estimates contributed to its lobbying activities. 2993915 1861682 1132233 1132233 Payroll Payable 511655 Accrued Vacation 747265 Other Accrued Liabilities 196008 1454928 X 28219105 -868 -868 28219973 0 28219973 26886139 0 26886139 0 26886139 Part X, Line 2: Palo Alto Veterans Institute for Research is a nonprofit corporation exempt from federal income tax under Internal Revenue Code section 501(c)(3) and state income tax under California Revenue and Taxation Code section 23701d. The Organization qualifies for the charitable contribution deduction under IRC section 170(b)(1)(A)(iii) and has been classified as an Organization that is not a private foundation under section 509(a)(1). As of September 30, 2016, the Organization had no unrecognized tax benefits or uncertain tax positions requiring accrual. Therefore, no provision for income taxes has been provided in the financial statements. X X 0 0 0 0 0 0 0 0 0 KERSTIN LYNAM CEO 244331 0 6000 0 0 0 23484 0 12397 0 286212 0 0 0 MARY THORNTON IT Director 135002 0 0 0 0 0 12420 0 7539 0 154961 0 0 0 STEPHANIE L HENSEY DATABASE MANAGER I 129315 0 0 0 0 0 12161 0 10682 0 152158 0 0 0 990, Part III, Line 1 Mission Statement: THE MISSION OF THE PALO ALTO VETERANS INSTITUTE FOR RESEARCH (PAVIR) IS ADVANCING VETERANS AND PUBLIC HEALTH THROUGH INNOVATIVE RESEARCH. PAVIR WORKS WITH MORE THAN 100 RESEARCHERS AND 250 STAFF TO SUPPORT BASIC SCIENCE AND CLINICAL RESEARCH TO REALIZE ITS MISSION. PAVIR'S RESEARCH SPANS THE INVESTIGATION OF DISEASES IN THE LABORATORY TO TESTING NEW DRUG TREATMENTS, AND DEVELOPING IMPROVED MODELS OF HEALTH CARE DELIVERY. IN ADDITION TO A FOCUS ON BASIC SCIENCE AND sIGNIFICANT DATA RESEARCH, PAVIR'S MEDICAL RESEARCH ADDRESSES HEALTH CHALLENGES THAT HAVE BEEN FACED ESPECIALLY BY VETERANS, INCLUDING POST TRAUMATIC STRESS DISORDER AND TRAUMATIC BRAIN INJURY, GERIATRIC MEDICINE, REHABILITATION, SLEEP, AND OTHER VETERANS AND PUBLIC HEALTH DISEASES. IN ADDITION TO RESEARCHERS' APPOINTMENT AT THE VA PALO ALTO HEALTH CARE SYSTEM, MOST HOLD DUAL APPOINTMENTS AT THE STANFORD UNIVERSITY SCHOOL OF MEDICINE. Form 990, Part VI, Section B, line 11 THE FORM 990 HAS BEEN PROVIDED TO ALL BOARD MEMBERS FOR THEIR REVIEW AND APPROVAL PRIOR TO THE FILING OF ALL RELATED TAX FORMS. Form 990, Part VI, Section B, line 12c EACH YEAR, PAVIR'S DIRECTORS AND OFFICERS MUST REVIEW PAVIR'S CONFLICT OF INTEREST POLICY AND COMPLETE AND SIGN A CONFLICT OF INTEREST DISCLOSURE QUESTIONNAIRE, DISCLOSING ANY POTENTIAL AREAS OF CONFLICT OF INTEREST OCCURRING DURING THE PRECEDING 12 MONTHS. In addition, directors and officers are required to complete annual conflict of interest policy training. Form 990, Part VI, Section B, line 15 The PAVIR HR Director conducted a compensation study for executive positions, utilizing data from comparable organizations based on geography, industry and revenue. The study was presented to the Board of Directors for review and approval. The Board convened an executive session, during which the compensation data was used to make executive compensation decisions. The Board decisions regarding executive compensation was documented in file. Form 990, Part VI, Section C, line 19 The audited financial statements, organizing/governing documents, and conflict of interest policy are available upon written request. Form 990 PART VII; SCH. J, PART II; SCH. L, PART IV; & Sch. R, Part V, 1n COMPENSATION FROM RELATED ORGANIZATION: ON 3/15/17, BONNIE LIANG WROTE TO EACH OF THE 7 BOARD MEMBERS WHO ARE COMPENSATED BY THE VA PALO ALTO HEALTH CARE SYSTEM REQUESTING PERMISSION TO OBTAIN HIS/HER COMPENSATION INFORMATION FOR THE TAX YEAR ENDING 12/31/15. IN RESPONSE, ALL BOARD MEMBERS DECLINED IN WRITING TO PROVIDE THEIR COMPENSATION INFORMATION. VA PALO ALTO HEALTH CARE SYSTEM 3801 MIRANDA AVENUE PALO ALTO CA 94304 941179505 tEACHING HOSPITAL, PROVIDING A FULL RANGE OF PATIENT CARE SERVICES CA 501(c)(1) N/A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 VA PALO ALTO HEALTH CARE SYSTEM N 185033 Fair Market Value va PALO ALTO HEALTH CARE SYSTEM O 78863 fair Market Value