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EXPENDITURE RESPONSIBILITY GRANT AGREEMENT EXECUTED BY GRANTEE PRIOR TO THE GRANT. THE PURPOSE OF THE GRANT IS TO SUPPORT GRANTEE'S MISSION TO IMPROVE HUMAN HEALTH THROUGH INTERNATIONAL EFFORTS TO COMBAT CARDIOVASCULAR AND NEUROVASCULAR DISEASE. THIS GRANT WAS SENT IN THE FOLLOWING INSTALLMENTS: JAN 1, 2024; MAY 10, 2024; AUGUST 23, 2024; NOVEMBER 8, 2024. 198060 NONE TO THE KNOWLEDGE OF THE LEDUCQ FOUNDATION. 2024 FORMAL WRITTEN REPORT WAS RECEIVED ON MARCH 4, 2025. 2025-03-04 THE 2024 FORMAL WRITTEN REPORT FOR THE PERIOD COVERING THE 2024 GRANT REFLECTS EXPENDITURE OF ENTIRE 2024 GRANT. CARLYLE EUROPE REAL ESTATE PARTNERS III, L.P. FMV 1071420 24458 DEERFIELD PRIVATE DESIGN FUND III, L.P. FMV 2916624 2625857 DEERFIELD PRIVATE DESIGN FUND IV, L.P. FMV 3903273 6035152 OF IV INVESTORS, LP FMV 1143205 2096617 PIVOTNORTH FUND II, LP FMV 246539 1519172 RESOURCE CAPITAL FUND VI L.P. 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