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        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>TERRIAWKIA WOODS-CAMPBELL MD</PersonNm>
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        <HighestCompensatedEmployeeInd>X</HighestCompensatedEmployeeInd>
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        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>HAYLEY VOIGE DO</PersonNm>
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        <ReportableCompFromRltdOrgAmt>0</ReportableCompFromRltdOrgAmt>
        <OtherCompensationAmt>7825</OtherCompensationAmt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>ROBERT C RAINEY MD</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>FLOYD C WATSON MD</PersonNm>
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        <HighestCompensatedEmployeeInd>X</HighestCompensatedEmployeeInd>
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      <Form990PartVIISectionAGrp>
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        <HighestCompensatedEmployeeInd>X</HighestCompensatedEmployeeInd>
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      <ProgramServiceRevenueGrp>
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        <TotalRevenueColumnAmt>86259</TotalRevenueColumnAmt>
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        <RelatedOrExemptFuncIncomeAmt>12302707</RelatedOrExemptFuncIncomeAmt>
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        <ProgramServicesAmt>27083913</ProgramServicesAmt>
        <ManagementAndGeneralAmt>837647</ManagementAndGeneralAmt>
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        <ProgramServicesAmt>1685389</ProgramServicesAmt>
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        <ProgramServicesAmt>1893134</ProgramServicesAmt>
        <ManagementAndGeneralAmt>92563</ManagementAndGeneralAmt>
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      <FeesForServicesLegalGrp>
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        <ManagementAndGeneralAmt>23556</ManagementAndGeneralAmt>
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      <FeesForServicesAccountingGrp>
        <TotalAmt>81798</TotalAmt>
        <ManagementAndGeneralAmt>81798</ManagementAndGeneralAmt>
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      <FeesForServicesOtherGrp>
        <TotalAmt>849123</TotalAmt>
        <ProgramServicesAmt>679299</ProgramServicesAmt>
        <ManagementAndGeneralAmt>169824</ManagementAndGeneralAmt>
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      <OfficeExpensesGrp>
        <TotalAmt>285494</TotalAmt>
        <ProgramServicesAmt>256945</ProgramServicesAmt>
        <ManagementAndGeneralAmt>28549</ManagementAndGeneralAmt>
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      <InformationTechnologyGrp>
        <TotalAmt>160722</TotalAmt>
        <ProgramServicesAmt>144650</ProgramServicesAmt>
        <ManagementAndGeneralAmt>16072</ManagementAndGeneralAmt>
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      <OccupancyGrp>
        <TotalAmt>4259882</TotalAmt>
        <ProgramServicesAmt>4046888</ProgramServicesAmt>
        <ManagementAndGeneralAmt>212994</ManagementAndGeneralAmt>
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      <TravelGrp>
        <TotalAmt>496811</TotalAmt>
        <ProgramServicesAmt>447130</ProgramServicesAmt>
        <ManagementAndGeneralAmt>49681</ManagementAndGeneralAmt>
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      <DepreciationDepletionGrp>
        <TotalAmt>718466</TotalAmt>
        <ProgramServicesAmt>718466</ProgramServicesAmt>
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      <InsuranceGrp>
        <TotalAmt>126557</TotalAmt>
        <ProgramServicesAmt>40000</ProgramServicesAmt>
        <ManagementAndGeneralAmt>86557</ManagementAndGeneralAmt>
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      <OtherExpensesGrp>
        <Desc>PHARMACEUTICALS</Desc>
        <TotalAmt>3690615</TotalAmt>
        <ProgramServicesAmt>3690615</ProgramServicesAmt>
      </OtherExpensesGrp>
      <OtherExpensesGrp>
        <Desc>CLINICAL SUPPLIES</Desc>
        <TotalAmt>2728303</TotalAmt>
        <ProgramServicesAmt>2728303</ProgramServicesAmt>
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      <OtherExpensesGrp>
        <Desc>RECRUITING</Desc>
        <TotalAmt>156192</TotalAmt>
        <ProgramServicesAmt>140573</ProgramServicesAmt>
        <ManagementAndGeneralAmt>15619</ManagementAndGeneralAmt>
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      <OtherExpensesGrp>
        <Desc>MISCELLANEOUS</Desc>
        <TotalAmt>151112</TotalAmt>
        <ProgramServicesAmt>136001</ProgramServicesAmt>
        <ManagementAndGeneralAmt>15111</ManagementAndGeneralAmt>
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      <TotalFunctionalExpensesGrp>
        <TotalAmt>49747887</TotalAmt>
        <ProgramServicesAmt>47227729</ProgramServicesAmt>
        <ManagementAndGeneralAmt>2520158</ManagementAndGeneralAmt>
        <FundraisingAmt>0</FundraisingAmt>
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      <CashNonInterestBearingGrp>
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        <EOYAmt>10840</EOYAmt>
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      <SavingsAndTempCashInvstGrp>
        <BOYAmt>11229200</BOYAmt>
        <EOYAmt>10095312</EOYAmt>
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      <AccountsReceivableGrp>
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        <EOYAmt>7316069</EOYAmt>
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      <OthNotesLoansReceivableNetGrp>
        <BOYAmt>1587949</BOYAmt>
        <EOYAmt>1270287</EOYAmt>
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      <InventoriesForSaleOrUseGrp>
        <BOYAmt>539508</BOYAmt>
        <EOYAmt>511633</EOYAmt>
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      <PrepaidExpensesDefrdChargesGrp>
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        <EOYAmt>85827</EOYAmt>
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      <LandBldgEquipCostOrOtherBssAmt>10843542</LandBldgEquipCostOrOtherBssAmt>
      <LandBldgEquipAccumDeprecAmt>3701381</LandBldgEquipAccumDeprecAmt>
      <LandBldgEquipBasisNetGrp>
        <BOYAmt>7731468</BOYAmt>
        <EOYAmt>7142161</EOYAmt>
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        <EOYAmt>26432129</EOYAmt>
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      <AccountsPayableAccrExpnssGrp>
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        <EOYAmt>2487377</EOYAmt>
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      <DeferredRevenueGrp>
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        <EOYAmt>1695908</EOYAmt>
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      <TotalLiabilitiesGrp>
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        <EOYAmt>4183285</EOYAmt>
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      <OrgDoesNotFollowSFAS117Ind>X</OrgDoesNotFollowSFAS117Ind>
      <CapStkTrPrinCurrentFundsGrp>
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        <EOYAmt>22248844</EOYAmt>
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      <PdInCapSrplsLandBldgEqpFundGrp>
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        <EOYAmt>0</EOYAmt>
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      <RtnEarnEndowmentIncmOthFndsGrp>
        <BOYAmt>0</BOYAmt>
        <EOYAmt>0</EOYAmt>
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      <TotalNetAssetsFundBalanceGrp>
        <BOYAmt>21404361</BOYAmt>
        <EOYAmt>22248844</EOYAmt>
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      <TotLiabNetAssetsFundBalanceGrp>
        <BOYAmt>26595411</BOYAmt>
        <EOYAmt>26432129</EOYAmt>
      </TotLiabNetAssetsFundBalanceGrp>
      <ReconcilationRevenueExpnssAmt>844483</ReconcilationRevenueExpnssAmt>
      <OtherChangesInNetAssetsAmt>0</OtherChangesInNetAssetsAmt>
      <InfoInScheduleOPartXIIInd>X</InfoInScheduleOPartXIIInd>
      <MethodOfAccountingAccrualInd>X</MethodOfAccountingAccrualInd>
      <AccountantCompileOrReviewInd>0</AccountantCompileOrReviewInd>
      <FSAuditedInd>1</FSAuditedInd>
      <FSAuditedBasisGrp>
        <SeparateBasisFinclStmtInd>X</SeparateBasisFinclStmtInd>
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      <AuditCommitteeInd>1</AuditCommitteeInd>
      <FederalGrantAuditRequiredInd>1</FederalGrantAuditRequiredInd>
      <FederalGrantAuditPerformedInd>1</FederalGrantAuditPerformedInd>
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    <IRS990ScheduleA documentId="RetDoc1039100001">
      <PublicOrganization170Ind>X</PublicOrganization170Ind>
      <GiftsGrantsContriRcvd170Grp>
        <CurrentTaxYearMinus4YearsAmt>31535584</CurrentTaxYearMinus4YearsAmt>
        <CurrentTaxYearMinus3YearsAmt>29387770</CurrentTaxYearMinus3YearsAmt>
        <CurrentTaxYearMinus2YearsAmt>29758843</CurrentTaxYearMinus2YearsAmt>
        <CurrentTaxYearMinus1YearAmt>35962988</CurrentTaxYearMinus1YearAmt>
        <CurrentTaxYearAmt>38203404</CurrentTaxYearAmt>
        <TotalAmt>164848589</TotalAmt>
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      <TotalCalendarYear170Grp>
        <CurrentTaxYearMinus4YearsAmt>31535584</CurrentTaxYearMinus4YearsAmt>
        <CurrentTaxYearMinus3YearsAmt>29387770</CurrentTaxYearMinus3YearsAmt>
        <CurrentTaxYearMinus2YearsAmt>29758843</CurrentTaxYearMinus2YearsAmt>
        <CurrentTaxYearMinus1YearAmt>35962988</CurrentTaxYearMinus1YearAmt>
        <CurrentTaxYearAmt>38203404</CurrentTaxYearAmt>
        <TotalAmt>164848589</TotalAmt>
      </TotalCalendarYear170Grp>
      <PublicSupportTotal170Amt>164848589</PublicSupportTotal170Amt>
      <GrossInvestmentIncome170Grp>
        <CurrentTaxYearMinus4YearsAmt>203907</CurrentTaxYearMinus4YearsAmt>
        <CurrentTaxYearMinus3YearsAmt>162963</CurrentTaxYearMinus3YearsAmt>
        <CurrentTaxYearMinus2YearsAmt>132823</CurrentTaxYearMinus2YearsAmt>
        <CurrentTaxYearMinus1YearAmt>125685</CurrentTaxYearMinus1YearAmt>
        <CurrentTaxYearAmt>86259</CurrentTaxYearAmt>
        <TotalAmt>711637</TotalAmt>
      </GrossInvestmentIncome170Grp>
      <TotalSupportAmt>165560226</TotalSupportAmt>
      <GrossReceiptsRltdActivitiesAmt>56003472</GrossReceiptsRltdActivitiesAmt>
      <PublicSupportCY170Pct>0.99570</PublicSupportCY170Pct>
      <PublicSupportPY170Pct>0.99460</PublicSupportPY170Pct>
      <ThirtyThrPctSuprtTestsCY170Ind>X</ThirtyThrPctSuprtTestsCY170Ind>
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    <IRS990ScheduleB documentId="RetDoc1234500001">
      <ContributorInformationGrp>
        <ContributorNum>RESTRICTED</ContributorNum>
        <ContributorBusinessName>
          <BusinessNameLine1>RESTRICTED</BusinessNameLine1>
        </ContributorBusinessName>
        <ContributorUSAddress>
          <AddressLine1>RESTRICTED</AddressLine1>
          <AddressLine2>RESTRICTED</AddressLine2>
          <City>RESTRICTED</City>
          <State>RESTRICTED</State>
          <ZIPCode>RESTRICTED</ZIPCode>
        </ContributorUSAddress>
        <TotalContributionsAmt>RESTRICTED</TotalContributionsAmt>
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    <IRS990ScheduleD documentId="RetDoc1040000001">
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        <OtherCostOrOtherBasisAmt>228680</OtherCostOrOtherBasisAmt>
        <BookValueAmt>228680</BookValueAmt>
      </LandGrp>
      <BuildingsGrp>
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        <DepreciationAmt>269358</DepreciationAmt>
        <BookValueAmt>1192858</BookValueAmt>
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      <LeaseholdImprovementsGrp>
        <OtherCostOrOtherBasisAmt>5408222</OtherCostOrOtherBasisAmt>
        <DepreciationAmt>1151469</DepreciationAmt>
        <BookValueAmt>4256753</BookValueAmt>
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      <EquipmentGrp>
        <OtherCostOrOtherBasisAmt>3744424</OtherCostOrOtherBasisAmt>
        <DepreciationAmt>2280554</DepreciationAmt>
        <BookValueAmt>1463870</BookValueAmt>
      </EquipmentGrp>
      <TotalBookValueLandBuildingsAmt>7142161</TotalBookValueLandBuildingsAmt>
      <FootnoteTextInd>X</FootnoteTextInd>
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      <RevenueNotReportedAmt>0</RevenueNotReportedAmt>
      <RevenueSubtotalAmt>49841575</RevenueSubtotalAmt>
      <OtherRevenuesNotIncludedAmt>750795</OtherRevenuesNotIncludedAmt>
      <RevenueNotReportedFinclStmtAmt>750795</RevenueNotReportedFinclStmtAmt>
      <TotalRevenuePerForm990Amt>50592370</TotalRevenuePerForm990Amt>
      <TotExpnsEtcAuditedFinclStmtAmt>47819892</TotExpnsEtcAuditedFinclStmtAmt>
      <ExpensesNotReportedAmt>0</ExpensesNotReportedAmt>
      <ExpensesSubtotalAmt>47819892</ExpensesSubtotalAmt>
      <OtherExpensesNotIncludedAmt>1927995</OtherExpensesNotIncludedAmt>
      <ExpensesNotRptFinclStmtAmt>1927995</ExpensesNotRptFinclStmtAmt>
      <TotalExpensesPerForm990Amt>49747887</TotalExpensesPerForm990Amt>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>PART X, LINE 2:</FormAndLineReferenceDesc>
        <ExplanationTxt>FEDERAL AND STATE TAXES THE INTERNAL REVENUE SERVICE HAS RULED THAT THE CENTER QUALIFIES AS AN ORGANIZATION DESCRIBED IN SECTION 501(C)(3) OF THE INTERNAL REVENUE CODE AND, ACCORDINGLY, IS GENERALLY EXEMPT FROM FEDERAL INCOME TAXES. ADDITIONALLY, THE CENTER HAS BEEN GRANTED EXEMPTION FROM STATE INCOME AND SALES TAXES BY THE STATE OF TEXAS COMPTROLLER'S OFFICE. THE CENTER RECOGNIZES THE EFFECT OF INCOME TAX POSITIONS (INCLUDING WHETHER EXEMPT INCOME MIGHT BE DETERMINED TO BE UNRELATED BUSINESS INCOME AND WHETHER IT HAS PROPERLY MAINTAINED ITS EXEMPT STATUS) IF SUCH POSITIONS ARE PROBABLE OF BEING SUSTAINED (I.E., PROBABLE THAT ADJUSTMENTS WOULD NOT BE DETECTED AND MADE BY TAXING AUTHORITIES). RECOGNIZED INCOME TAX PROVISIONS ARE MEASURED AT THE LARGEST AMOUNT THAT IS GREATER THAN 50% OF BEING REALIZED. CHANGES IN THE RECOGNITION OR MEASUREMENT ARE REFLECTED IN THE PERIOD IN WHICH THE CHANGE IN JUDGMENT OCCURS. THE CENTER RECORDS INTEREST AND PENALTIES RELATED TO UNRECOGNIZED TAX BENEFITS IN MANAGEMENT AND GENERAL EXPENSES.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>PART XI, LINE 4B - OTHER ADJUSTMENTS:</FormAndLineReferenceDesc>
        <ExplanationTxt>FISCAL YEAR OF 9/30 ON AUDIT VS. CALENDAR YEAR 12/31 ON FORM 990(TIMING) 750,795.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>PART XII, LINE 4B - OTHER ADJUSTMENTS:</FormAndLineReferenceDesc>
        <ExplanationTxt>FISCAL YEAR OF 9/30 ON AUDIT VS CALENDAR YEAR 12/31 ON FORM 990 (TIMING DIFF 1,927,995.</ExplanationTxt>
      </SupplementalInformationDetail>
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      <CompensationSurveyInd>X</CompensationSurveyInd>
      <BoardOrCommitteeApprovalInd>X</BoardOrCommitteeApprovalInd>
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      <SupplementalNonqualRtrPlanInd>0</SupplementalNonqualRtrPlanInd>
      <EquityBasedCompArrngmInd>0</EquityBasedCompArrngmInd>
      <CompBasedOnRevenueOfFlngOrgInd>0</CompBasedOnRevenueOfFlngOrgInd>
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      <CompBsdNetEarnsFlngOrgInd>0</CompBsdNetEarnsFlngOrgInd>
      <CompBsdNetEarnsRltdOrgsInd>0</CompBsdNetEarnsRltdOrgsInd>
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      <InitialContractExceptionInd>0</InitialContractExceptionInd>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>ROLAND GOERTZ MD</PersonNm>
        <TitleTxt>CEO</TitleTxt>
        <BaseCompensationFilingOrgAmt>440672</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>0</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>0</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>0</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>0</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>0</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>7825</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>448497</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>D MICHAEL HARDIN MD</PersonNm>
        <TitleTxt>RESIDENCY PROGRAM DIRECTOR</TitleTxt>
        <BaseCompensationFilingOrgAmt>222312</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>0</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>0</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>0</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>0</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>0</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>7825</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>230137</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
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        <ExplanationTxt>THE ORGANIZATION WAS A PARTY TO A BUSINESS TRANSACTION WITH ANOTHER CHARITABLE ORGANIZATION OF WHICH SOME OF THE CURRENT OFFICERS OR DIRECTORS ARE ALSO OFFICERS OR DIRECTORS. ACCORDING TO THE IRS INSTRUCTIONS FOR SCHEDULE L, TAX-EXEMPT ORGANIZATIONS ARE NOT INCLUDED IN THE DEFINITION OF INTERESTED PARTIES FOR WHICH DISCLOSURE OF TRANSACTIONS MUST BE MADE; THEREFORE, THE TRANSACTIONS ARE NOT INLCUDED IN PART IV OF SCHEDULE L. BECAUSE THE QUESTION ON PAGE 4, LINE 28C DOES NOT INDICATE THE EXCEPTION,THE ORGANIZATION HAS ANSWERED "YES" TO LINE 28C.</ExplanationTxt>
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        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION B, LINE 11B</FormAndLineReferenceDesc>
        <ExplanationTxt>COPY MAILED TO BOARD MEMBERS. OPPORTUNITY TO DISCUSS PRESENTED AT BOARD MEETING.</ExplanationTxt>
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      <SupplementalInformationDetail>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION B, LINE 15</FormAndLineReferenceDesc>
        <ExplanationTxt>COMPENSATION IS DETERMINED BY THE BOARD ANNUALLY FOR THE EXECUTIVE DIRECTOR(CEO) AND BY THE EXECUTIVE DIRECTOR ANNUALLY FOR OTHER KEY EMPLOYEES. SALARIES ARE SET BASED ON INDUSTRY STANDARDS. THE DECISIONS REGARDING SALARIES ARE RECORDED IN THE BOARD MINUTES AND IN EMPLOYEE RECORDS AS PART OF THEIR PERFORMANCE REVIEW PROCESS. ALSO, THE DETERMINATION OF SALARIES IS AN INHERENT ASPECT OF THE ANNUAL BUDGETING PROCESS.</ExplanationTxt>
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      <SupplementalInformationDetail>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART XII, LINE 2C:</FormAndLineReferenceDesc>
        <ExplanationTxt>THE PROCESS HAS NOT CHANGED FROM THE PRIOR YEARS.</ExplanationTxt>
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</Return>